|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Center MM, Jemal A, Smith RA and Ward E:
Worldwide variations in colorectal cancer. CA Cancer J Clin.
59:366–378. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cottrell S, Bicknell D, Kaklamanis L and
Bodmer WF: Molecular analysis of apc mutations in familial
adenomatous polyposis and sporadic colon carcinomas. Lancet.
340:626–630. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lengauer C, Kinzler KW and Vogelstein B:
Genetic instabilities in human cancers. Nature. 396:643–649. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Macfarlane SR, Seatter MJ, Kanke T, Hunter
GD and Plevin R: Proteinase-activated receptors. Pharmacol Rev.
53:245–282. 2001.PubMed/NCBI
|
|
6
|
Yu G, Jiang P, Xiang Y and Zhang Y, Zhu Z,
Zhang C, Lee S, Lee W and Zhang Y: Increased expression of
protease-activated receptor 4 and trefoil factor 2 in human
colorectal cancer. PLoS One. 10:e01226782015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Zhang Y, Yu G, Jiang P, Xiang Y, Li W, Lee
W and Zhang Y: Decreased expression of protease-activated receptor
4 in human gastric cancer. Int J Biochem Cell Biol. 43:1277–1283.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Li SM, Jiang P, Xiang Y, Wang WW, Zhu YC,
Feng WY, Li SD and Yu GY: Protease-activated receptor (par)1, par2
and par4 expressions in esophageal squamous cell carcinoma.
Dongwuxue Yanjiu. 35:420–425. 2014.PubMed/NCBI
|
|
9
|
Jiang P, Yu GY and Zhang Y, Xiang Y, Hua
HR, Bian L, Wang CY, Lee WH and Zhang Y: Down-regulation of
protease-activated receptor 4 in lung adenocarcinoma is associated
with a more aggressive phenotype. Asian Pac J Cancer Prev.
14:3793–3798. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lee S, Jiang P, Wang W, Feng W and Yu G:
The decreased expression of protease-activated receptor 4 in
esophageal squamous carcinoma. Neoplasma. 61:546–552. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Elste AP and Petersen I: Expression of
proteinase-activated receptor 1–4 (par 1–4) in human cancer. J Mol
Histol. 41:89–99. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Darmoul D, Gratio V, Devaud H, Lehy T and
Laburthe M: Aberrant expression and activation of the thrombin
receptor protease-activated receptor-1 induces cell proliferation
and motility in human colon cancer cells. Am J Pathol.
162:1503–1513. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Booden MA, Eckert LB, Der CJ and Trejo J:
Persistent signaling by dysregulated thrombin receptor trafficking
promotes breast carcinoma cell invasion. Mol Cell Boil.
24:1990–1999. 2004. View Article : Google Scholar
|
|
14
|
Kaufmann R, Rahn S, Pollrich K, Hertel J,
Dittmar Y, Hommann M, Henklein P, Biskup C, Westermann M,
Hollenberg MD and Settmacher U: Thrombin-mediated hepatocellular
carcinoma cell migration: Cooperative action via
proteinase-activated receptors 1 and 4. J Cell Physiol.
211:699–707. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Kaufmann R, Junker U, Nuske K, Westermann
M, Henklein P, Scheele J and Junker K: Par-1- and par-3-type
thrombin receptor expression in primary cultures of human renal
cell carcinoma cells. Int J Oncol. 20:177–180. 2002.PubMed/NCBI
|
|
16
|
Segal L, Katz LS, Shapira H, Sandbank J,
Geras-Raaka E, Gershengorn MC and Oron Y: Par-3 knockdown enhances
adhesion rate of panc-1 cells via increased expression of
integrinalphav and e-cadherin. PloS One. 9:e938792014. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Greenberg DL, Mize GJ and Takayama TK:
Protease-activated receptor mediated rhoa signaling and
cytoskeletal reorganization in lncap cells. Biochemistry.
42:702–709. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Huang YQ, Li JJ and Karpatkin S: Thrombin
inhibits tumor cell growth in association with up-regulation of
p21(waf/cip1) and caspases via a p53-independent, stat-1-dependent
pathway. J Boil Chem. 275:6462–6468. 2000. View Article : Google Scholar
|
|
19
|
Gratio V, Walker F, Lehy T, Laburthe M and
Darmoul D: Aberrant expression of proteinase-activated receptor 4
promotes colon cancer cell proliferation through a persistent
signaling that involves src and erbb-2 kinase. Int J Cancer.
124:1517–1525. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yu G, Lee YC, Cheng CJ, Wu CF, Song JH,
Gallick GE, Yu-Lee LY, Kuang J and Lin SH: Rsk promotes prostate
cancer progression in bone through ing3, ckap2, and ptk6-mediated
cell survival. Mol Cancer Res. 13:348–357. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang Y, Yu G, Wang Y, Xiang Y, Gao Q,
Jiang P, Zhang J, Lee W and Zhang Y: Activation of
protease-activated receptor (par) 1 by frog trefoil factor (tff) 2
and par4 by human tff2. Cell Mol Life Sci. 68:3771–3780. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Sambrano GR, Weiss EJ, Zheng YW, Huang W
and Coughlin SR: Role of thrombin signalling in platelets in
haemostasis and thrombosis. Nature. 413:74–78. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kataoka H, Hamilton JR, McKemy DD, Camerer
E, Zheng YW, Cheng A, Griffin C and Coughlin SR: Protease-activated
receptors 1 and 4 mediate thrombin signaling in endothelial cells.
Blood. 102:3224–3231. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Bretschneider E, Kaufmann R, Braun M,
Nowak G, Glusa E and Schror K: Evidence for functionally active
protease-activated receptor-4 (par-4) in human vascular smooth
muscle cells. Br J Pharmacol. 132:1441–1446. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mußbach F, Henklein P, Westermann M,
Settmacher U, Bohmer FD and Kaufmann R: Proteinase-activated
receptor 1- and 4-promoted migration of hep3b hepatocellular
carcinoma cells depends on ros formation and rtk transactivation. J
Cancer Res Clin Oncol. 141:813–825. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sedda S, Marafini I, Caruso R, Pallone F
and Monteleone G: Proteinase activated-receptors-associated
signaling in the control of gastric cancer. World J Gastroenterol.
20:11977–11984. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Smith TH, Coronel LJ, Li JG, Dores MR,
Nieman MT and Trejo J: Protease-activated receptor-4 signaling and
trafficking is regulated by the clathrin adaptor protein complex-2
independent of β-arrestins. J Boil Chem. 291:18453–18464. 2016.
View Article : Google Scholar
|
