|
1
|
Worni M, Guller U, White RR, Castleberry
AW, Pietrobon R, Cerny T, Gloor B and Koeberle D: Modest
improvement in overall survival for patients with metastatic
pancreatic cancer: A trend analysis using the surveillance,
epidemiology, and end results registry from 1988 to 2008. Pancreas.
42:1157–1163. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ottaiano A, Capozzi M, De Divitiis C, De
Stefano A, Botti G, Avallone A and Tafuto S: Gemcitabine
mono-therapy versus gemcitabine plus targeted therapy in advanced
pancreatic cancer: A meta-analysis of randomized phase III trials.
Acta Oncol. 56:377–383. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bednar F and Simeone DM: Recent advances
in pancreatic surgery. Curr Opin Gastroenterol. 30:518–523. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ghaneh P, Smith R, Tudor-Smith C, Raraty M
and Neoptolemos JP: Neoadjuvant and adjuvant strategies for
pancreatic cancer. Eur J Surg Oncol. 34:297–305. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Viaud J, Brac C, Artru P, Le Pabic E,
Leconte B, Bodère A, Pracht M, Le Sourd S, Edeline J and Lièvre A:
Gemcitabine as second-line chemotherapy after Folfirinox failure in
advanced pancreatic adenocarcinoma: A retrospective study. Dig
Liver Dis. 49:692–696. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Massari F, Santoni M, Ciccarese C,
Brunelli M, Conti A, Santini D, Montironi R, Cascinu S and Tortora
G: Emerging concepts on drug resistance in bladder cancer:
Implications for future strategies. Crit Rev Oncol Hematol.
96:81–90. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Immordino ML, Brusa P, Rocco F, Arpicco S,
Ceruti M and Cattel L: Preparation, characterization, cytotoxicity
and pharmacokinetics of liposomes containing lipophilic gemcitabine
prodrugs. J Control Release. 100:331–346. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Kim CE, Lim SK and Kim JS: In vivo
antitumor effect of cromolyn in PEGylated liposomes for pancreatic
cancer. J Control Release. 157:190–195. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Maeda H, Wu J, Sawa T, Matsumura Y and
Hori K: Tumor vascular permeability and the EPR effect in
macromolecular therapeutics: A review. J Control Release.
65:271–284. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kirui DK, Celia C, Molinaro R, Bansal SS,
Cosco D, Fresta M, Shen H and Ferrari M: Mild hyperthermia enhances
transport of liposomal gemcitabine and improves in vivo therapeutic
response. Adv Healthc Mater. 4:1092–1103. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Shamir ER and Ewald AJ: Adhesion in
mammary development: Novel roles for E-cadherin in individual and
collective cell migration. Curr Top Dev Biol. 112:353–382. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Nicoletti I, Migliorati G, Pagliacci MC,
Grignani F and Riccardi C: A rapid and simple method for measuring
thymocyte apoptosis by propidium iodide staining and flow
cytometry. J Immunol Methods. 139:271–279. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hobot J, Carlemalm E, Villiger W and
Kellenberger E: Periplasmic Gel: New concept resulting from the
reinvestigation of bacterial cell envelope ultrastructure by new
methods. J Bacteriol. 160:143–152. 1984.PubMed/NCBI
|
|
15
|
Li E, Ambrosini G, Chu EY, Plescia J,
Tognin S, Marchisio PC and Altieri DC: Control of apoptosis and
mitotic spindle checkpoint by survivin. Nature. 396:580–584. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gaitanaki C, Mastri M, Aggeli IK and Beis
I: Differential roles of p38-MAPK and JNKs in mediating early
protection or apoptosis in the hyperthermic perfused amphibian
heart. J Exp Biol. 211:2524–2532. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2016. CA Cancer J Clin. 66:7–30. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
de Sousa Cavalcante L and Monteiro G:
Gemcitabine: Metabolism and molecular mechanisms of action,
sensitivity and chemoresistance in pancreatic cancer. Eur J
Pharmacol. 741:8–16. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
van der Zee J: Heating the patient: A
promising approach? Ann Oncol. 13:1173–1184. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Falk MH and Issels RD: Hyperthermia in
oncology. Int J Hyperthermia. 17:1–18. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
San-Miguel ICB, Vallejo D, Álvarez M,
Prieto J, González-Gallego J and Tuñón MJ: Melatonin modulates the
autophagic response in acute liver failure induced by the rabbit
hemorrhagic disease virus. J Pineal Res. 56:313–321. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Guo Y, Ziesch A, Hocke S, Kampmann E, Ochs
S, De Toni EN, Göke B and Gallmeier E: Overexpression of heat shock
protein 27 (HSP27) increases gemcitabine sensitivity inpancreatic
cancer cells through S-phase arrest and apoptosis. J Cell Mol Med.
19:340–350. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Nakajima K, Yanagawa T, Watanabe H and
Takagishi K: Hyperthermia reduces migration of osteosarcoma by
suppression of autocrine motilityfactor. Oncol Rep. 28:1953–1958.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Jin S, Shen JN, Wang J, Huang G and Zhou
JG: Oridonin induced apoptosis through Akt and MAPKs signaling
pathways in human osteosarcoma cells. Cancer Biol Ther. 6:261–268.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Cheng Y, Qiu F, Ye YC, Tashiro S, Onodera
S and Ikejima T: Oridonin induces G2/M arrest and apoptosis via
activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK
survival pathway in murine fibrosarcoma L929 cells. Arch Biochem
Biophys. 490:70–75. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Shi Y: Caspase activation: Revisiting the
induced proximity model. Cell. 117:855–858. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Takeda H, Okada M, Suzuki S, Kuramoto K,
Sakaki H, Watarai H, Sanomachi T, Seino S, Yoshioka T and Kitanaka
C: Rho-associated protein kinase (ROCK) inhibitors inhibit survivin
expression and sensitize pancreatic cancer stem cells to
gemcitabine. Anticancer Res. 36:6311–6318. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Filomeni G, De Zio D and Cecconi F:
Oxidative stress and autophagy: The clash between damage and
metabolic needs. Cell Death Differ. 22:377–388. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Renschler MF: The emerging role of
reactive oxygen species in cancer therapy. Eur J Cancer.
40:1934–1940. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Toler SM, Noe D and Sharma A: Selective
enhancement of cellular oxidative stress by chloroquine:
Implications for the treatment of glioblastoma multiforme.
Neurosurg Focus. 21:E102006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Scandalios JG: Oxidative stress: Molecular
perception and transduction of signals triggering antioxidant gene
defenses. Braz J Med Biol Res. 38:995–1014. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Son Y, Cheong YK, Kim NH, Chung HT, Kang
DG and Pae HO: Mitogen-activated protein kinases and reactive
oxygen species: How can ROS activate MAPK pathways? J Signal
Transduct 2011. 7926392011.
|
|
33
|
Dhillon AS, Hagan S, Rath O and Kolch W:
MAP kinase signalling pathways in cancer. Oncogene. 26:3279–3290.
2017. View Article : Google Scholar
|
|
34
|
Liu QR, Liu JM, Chen Y, Xie XQ, Xiong XX,
Qiu XY, Pan F, Liu D, Yu SB and Chen XQ: Piperlongumine inhibits
migration of glioblastoma cells via activation of ROS-dependent p38
and JNK signaling pathways. Oxid Med Cell Longev. 2014:6537322014.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Goldsmith EJ, Min X, He H and Zhou T:
Structural studies of MAP kinase cascade components. Methods Mol
Biol. 661:223–237. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Johnson GL and Lapadat R:
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and
p38 protein kinases. Science. 298:1911–1912. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Lencioni R, Chen XP, Dagher L and Venook
AP: Treatment of intermediate/advanced hepatocellular carcinoma in
the clinic: How can outcomes be improved? Oncologist. 15 Suppl
4:S42–S52. 2010. View Article : Google Scholar
|
|
38
|
Katz M, Amit I and Yarden Y: Regulation of
MAPKs by growth factors and receptor tyrosine kinases. Biochim
Biophys Acta. 1773:1161–1176. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Tobiume K, Matsuzawa A, Takahashi T,
Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T and
Ichijo H: ASK1 is required for sustained activations of JNK/p38 MAP
kinases and apoptosis. EMBO Rep. 2:222–228. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Takeda K, Noguchi T, Naguro I and Ichijo
H: Apoptosis signal-regulating kinase 1 in stress and immune
response. Annu Rev Pharmacol Toxicol. 48:199–225. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Wu CC and Bratton SB: Regulation of the
intrinsic apoptosis pathway by reactive oxygen species. Antioxid
Redox Signal. 19:546–558. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Dhanasekaran DN and Reddy EP: JNK
signaling in apoptosis. Oncogene. 27:6245–6251. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chang L and Karin M: Mammalian MAP kinase
signalling cascades. Nature. 410:37–40. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Suzuki S, Okada M, Shibuya K, Seino M,
Sato A, Takeda H, Seino S, Yoshioka T and Kitanaka C: JNK
suppression of chemotherapeutic agents-induced ROS confers
chemoresistance on pancreatic cancer stem cells. Oncotarget.
6:458–470. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Sun ZL, Dong JL and Wu J: Juglanin induces
apoptosis and autophagy in human breast cancer progression via
ROS/JNK promotion. Biomed Pharmacother. 85:303–312. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Weston CR and Davis RJ: The JNK signal
transduction pathway. Curr Opin Genet Dev. 12:14–21. 2002.
View Article : Google Scholar : PubMed/NCBI
|
