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Article

Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer

  • Authors:
    • Jinling Zhang
    • Xueyuan Heng
    • Yi Luo
    • Luning Li
    • Haiyan Zhang
    • Fengyuan Che
    • Baosheng Li
  • View Affiliations / Copyright

    Affiliations: Department of Radiation Oncology, Shandong Cancer Hospital, Shandong Academy of Medical Sciences, Shandong University, Jinan, Shandong 250117, P.R. China, Department of Oncology, Linyi People's Hospital, Shandong University, School of Medicine, Linyi, Shandong 276000, P.R. China, Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48105, USA
  • Pages: 6705-6712
    |
    Published online on: September 18, 2018
       https://doi.org/10.3892/ol.2018.9456
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Abstract

A negative lymph node (NLN) may represent a stronger predictor for the overall survival (OS) rate of patients with esophageal squamous cell carcinoma (ESCC), when compared with a positive LN (PLN). The present study aimed to investigate which LN station, containing the NLN, was associated with OS rate. A retrospective review was conducted in 216 patients with ESCC and a forward stepwise Cox regression model analysis was used to assess the relationship between clinical parameters and OS rate. Patients were divided into subgroups according to the status of the LN at station 108. Survival analysis was performed using the Kaplan‑Meier method. The ratio of albumin‑to‑globulin (AGR), and of lymphocytes to neutrophil granulocytes (LNR) in the subgroups were also investigated. Overall, 105p (the PLN number at station 105), 108p, 109p and 7p were confirmed to be risk factors for OS rate (all P<0.05). Conversely, 108n (the NLN number at station 108) was identified as a protective factor for OS rate [hazard ratio (HR) 0.457, P=0.001]. Survival analysis demonstrated that patients with an NLN identified at the station 108 had an improved OS rate compared with those with a PLN identified at station 108 (P=0.006). Patients with only an NLN identified at station 108 had the best OS rate among all the sub‑groups examined, and the AGR of this group of patients was higher than those of the other groups. The LN status at station 108 may indicate the prognosis of patients with ESCC, and an NLN may reflect the reaction of the immune system to tumor metastasis in these patients.
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1 

Li B, Chen H, Xiang J, Zhang Y, Kong Y, Garfield DH and Li H: Prevalence of lymph node metastases in superficial esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. 146:1198–1203. 2013. View Article : Google Scholar : PubMed/NCBI

2 

Merkow RP, Bilimoria KY, Keswani RN, Chung J, Sherman KL, Knab LM, Posner MC and Bentrem DJ: Treatment trends, risk of lymph node metastasis, and outcomes for localized esophageal cancer. J Natl Cancer Inst. 106:pii: dju1332014. View Article : Google Scholar

3 

McCormack VA, Menya D, Munishi MO, Dzamalala C, Gasmelseed N, Roux Leon M, Assefa M, Osano O, Watts M, Mwasamwaja AO, et al: Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting-specific exposures to known and putative risk factors. Int J Cancer. 140:259–271. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Du D, Song T, Liang X, Fang M and Wu S: Concurrent chemoradiotherapy with elective lymph node irradiation for esophageal cancer: A systemic review and pooled analysis of the literature. Dis Esophagus. 30:1–9. 2017.

5 

Liu J, Liu Q, Wang Y, Xia Z and Zhao G: Nodal skip metastasis is associated with a relatively poor prognosis in thoracic esophageal squamous cell carcinoma. Eur J Surg Oncol. 42:1202–1205. 2016. View Article : Google Scholar : PubMed/NCBI

6 

Dubecz A, Kern M, Solymosi N, Schweigert M and Stein HJ: Predictors of lymph node metastasis in surgically resected T1 esophageal cancer. Ann Thorac Surg. 99:1879–1886. 2015. View Article : Google Scholar : PubMed/NCBI

7 

Ren X, Zhao Z, Huang W, Liu H, Dong C and Li Y: Analysis of the characteristics and factors influencing lymph node metastasis in thoracic esophageal carcinoma and cancer of the gastric cardia. Hepatogastroenterology. 62:73–76. 2015.PubMed/NCBI

8 

Zhang D, Zheng Y, Wang Z, Huang Q, Cao X, Wang F and Liu S: Comparison of the 7th and proposed 8th editions of the AJCC/UICC TNM staging system for esophageal squamous cell carcinoma underwent radical surgery. Eur J Surg Oncol. 43:1949–1955. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Baba Y, Watanabe M, Shigaki H, Iwagami S, Ishimoto T, Iwatsuki M and Baba H: Negative lymph-node count is associated with survival in patients with resected esophageal squamous cell carcinoma. Surgery. 153:234–241. 2013. View Article : Google Scholar : PubMed/NCBI

10 

Kim KH, Chang JS, Cha JH, Lee IJ, Kim DJ, Cho BC, Park KR and Lee CG: Optimal adjuvant treatment for curatively resected thoracic esophageal squamous cell carcinoma: A radiotherapy perspective. Cancer Res Treat. 49:168–177. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Wang S, Wang Z, Yang Z, Liu Y, Liu X, Shang B and Jiang WP: Postoperative radiotherapy improves survival in stage pT2N0M0 esophageal squamous cell carcinoma with high risk of poor prognosis. Ann Surg Oncol. 23:265–272. 2016. View Article : Google Scholar : PubMed/NCBI

12 

Kajiyama Y: New Japanese classification of esophageal cancer (11th Edition). Gan To Kagaku Ryoho. 43:1049–1052. 2016.(In Japanese). PubMed/NCBI

13 

Cheng J, Kong L, Huang W, Li B, Li H, Wang Z, Zhang J, Zhou T and Sun H: Explore the radiotherapeutic clinical target volume delineation for thoracic esophageal squamous cell carcinoma from the pattern of lymphatic metastases. J Thorac Oncol. 8:359–365. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Greenstein AJ, Litle VR, Swanson SJ, Divino CM, Packer S and Wisnivesky JP: Effect of the number of lymph nodes sampled on postoperative survival of lymph node-negative esophageal cancer. Cancer. 112:1239–1246. 2008. View Article : Google Scholar : PubMed/NCBI

15 

Zhu Z, Chen H, Yu W, Fu X, Xiang J, Li H, Zhang Y, Sun M, Wei Q, Zhao W and Zhao K: Number of negative lymph nodes is associated with survival in thoracic esophageal squamous cell carcinoma patients undergoing three-field lymphadenectomy. Ann Surg Oncol. 21:2857–2863. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Hsu PK, Huang CS, Wang BY, Wu YC, Chou TY and Hsu WH: The prognostic value of the number of negative lymph nodes in esophageal cancer patients after transthoracic resection. Ann Thorac Surg. 96:995–1001. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Luketich JD, Kassis ES, Shriver SP, Nguyen NT, Schauer PR, Weigel TL, Yousem SA and Siegfried JM: Detection of micrometastases in histologically negative lymph nodes in esophageal cancer. Ann Thorac Surg. 66:1715–1718. 1998. View Article : Google Scholar : PubMed/NCBI

18 

Komukai S, Nishimaki T, Watanabe H, Ajioka Y, Suzuki T and Hatakeyama K: Significance of immunohistochemically demonstrated micrometastases to lymph nodes in esophageal cancer with histologically negative nodes. Surgery. 127:40–46. 2000. View Article : Google Scholar : PubMed/NCBI

19 

de Meer SG, Dauwan M, de Keizer B, Valk GD, Rinkes Borel IH and Vriens MR: Not the number but the location of lymph nodes matters for recurrence rate and disease-free survival in patients with differentiated thyroid cancer. World J Surg. 36:1262–1267. 2012. View Article : Google Scholar : PubMed/NCBI

20 

Tanaka H, Ohira M, Kubo N, Muguruma K, Yamashita Y, Sawada T and Hirakawa K: Association of location of lymph node metastases with postoperative recurrence of esophageal squamous cell carcinoma. Anticancer Res. 32:3421–3426. 2012.PubMed/NCBI

21 

Yang HX, Xu Y, Fu JH, Wang JY, Lin P and Rong TH: An evaluation of the number of lymph nodes examined and survival for node-negative esophageal carcinoma: Data from China. Ann Surg Oncol. 17:1901–1911. 2010. View Article : Google Scholar : PubMed/NCBI

22 

Lagergren J, Mattsson F, Zylstra J, Chang F, Gossage J, Mason R, Lagergren P and Davies A: Extent of lymphadenectomy and prognosis after esophageal cancer surgery. JAMA Surg. 151:32–39. 2016. View Article : Google Scholar : PubMed/NCBI

23 

van der Schaaf M, Johar A, Wijnhoven B, Lagergren P and Lagergren J: Extent of lymph node removal during esophageal cancer surgery and survival. J Natl Cancer Inst. 107:pii: djv0432015.

24 

Yodying H, Matsuda A, Miyashita M, Matsumoto S, Sakurazawa N, Yamada M and Uchida E: Prognostic significance of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in oncologic outcomes of esophageal cancer: A systematic review and meta-analysis. Ann Surg Oncol. 23:646–654. 2016. View Article : Google Scholar : PubMed/NCBI

25 

Sharaiha RZ, Halazun KJ, Mirza F, Port JL, Lee PC, Neugut AI, Altorki NK and Abrams JA: Elevated preoperative neutrophil: Lymphocyte ratio as a predictor of postoperative disease recurrence in esophageal cancer. Ann Surg Oncol. 18:3362–3369. 2011. View Article : Google Scholar : PubMed/NCBI

26 

Zhang F, Sun P, Wang ZQ, de Wang S, Wang Y, Zhang DS, Wang FH, Fu JH, Xu RH and Li YH: Low preoperative albumin-globulin score predicts favorable survival in esophageal squamous cell carcinoma. Oncotarget. 7:30550–30560. 2016.PubMed/NCBI

27 

Fukushima H, Kobayashi M, Kawano K and Morimoto S: Prognostic value of albumin/globulin ratio in patients with upper tract urothelial carcinoma patients treated with radical nephroureterectomy. Anticancer Res. 38:2329–2334. 2018.PubMed/NCBI

28 

He J, Pan H, Liang W, Xiao D, Chen X, Guo M and He J: Prognostic effect of Albumin-to-Globulin ratio in patients with solid tumors: A systematic review and meta-analysis. J Cancer. 8:4002–4010. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Suh B, Park S, Shin DW, Yun JM, Keam B, Yang HK, Ahn E, Lee H, Park JH and Cho B: Low albumin-to-globulin ratio associated with cancer incidence and mortality in generally healthy adults. Ann Oncol. 25:2260–2266. 2014. View Article : Google Scholar : PubMed/NCBI

30 

Shibutani M, Maeda K, Nagahara H, Ohtani H, Iseki Y, Ikeya T, Sugano K and Hirakawa K: The pretreatment albumin to globulin ratio predicts chemotherapeutic outcomes in patients with unresectable metastatic colorectal cancer. BMC Cancer. 15:3472015. View Article : Google Scholar : PubMed/NCBI

31 

Ji WH, Jiang YH, Ji YL, Li B and Mao WM: Prechemotherapy neutrophil : lymphocyte ratio is superior to the platelet : Lymphocyte ratio as a prognostic indicator for locally advanced esophageal squamous cell cancer treated with neoadjuvant chemotherapy. Dis Esophagus. 29:403–411. 2016. View Article : Google Scholar : PubMed/NCBI

32 

Yutong H, Xiaoli X, Shumei L, Shan S, Di L and Baoen S: Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with esophageal cancer in a high incidence area in China. Arch Med Res. 46:557–563. 2015. View Article : Google Scholar : PubMed/NCBI

33 

Xie X, Luo KJ, Hu Y, Wang JY and Chen J: Prognostic value of preoperative platelet-lymphocyte and neutrophil-lymphocyte ratio in patients undergoing surgery for esophageal squamous cell cancer. Dis Esophagus. 29:79–85. 2016. View Article : Google Scholar : PubMed/NCBI

34 

Matsuda S, Tsubosa Y, Niihara M, Sato H, Takebayashi K, Kawamorita K, Mori K, Tsushima T, Yasui H, Takeuchi H and Kitagawa Y: Distribution of lymph node metastasis and clinical validity of gastric tube reconstruction in lower thoracic esophageal squamous cell carcinoma with gastric invasion. Ann Surg Oncol. 22:617–623. 2015. View Article : Google Scholar : PubMed/NCBI

35 

Wilke TJ, Bhirud AR and Lin C: A review of the impact of preoperative chemoradiotherapy on outcome and postoperative complications in esophageal cancer patients. Am J Clin Oncol. 38:415–421. 2015. View Article : Google Scholar : PubMed/NCBI

36 

Yuasa Y, Seike J, Yoshida T, Takechi H, Yamai H, Yamamoto Y, Furukita Y, Goto M, Minato T, Nishino T, et al: Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer. Ann Surg Oncol. 19:486–493. 2012. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Zhang J, Heng X, Luo Y, Li L, Zhang H, Che F and Li B: Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer. Oncol Lett 16: 6705-6712, 2018.
APA
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., & Li, B. (2018). Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer. Oncology Letters, 16, 6705-6712. https://doi.org/10.3892/ol.2018.9456
MLA
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., Li, B."Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer". Oncology Letters 16.5 (2018): 6705-6712.
Chicago
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., Li, B."Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer". Oncology Letters 16, no. 5 (2018): 6705-6712. https://doi.org/10.3892/ol.2018.9456
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang J, Heng X, Luo Y, Li L, Zhang H, Che F and Li B: Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer. Oncol Lett 16: 6705-6712, 2018.
APA
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., & Li, B. (2018). Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer. Oncology Letters, 16, 6705-6712. https://doi.org/10.3892/ol.2018.9456
MLA
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., Li, B."Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer". Oncology Letters 16.5 (2018): 6705-6712.
Chicago
Zhang, J., Heng, X., Luo, Y., Li, L., Zhang, H., Che, F., Li, B."Negative lymph node at station 108 is a strong predictor of overall survival in esophageal cancer". Oncology Letters 16, no. 5 (2018): 6705-6712. https://doi.org/10.3892/ol.2018.9456
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