Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
January-2019 Volume 17 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2019 Volume 17 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma

  • Authors:
    • Yi Sang
    • Ruhua Zhang
    • Longhua Sun
    • Kaddie Kwok Chen
    • Si‑Wei Li
    • Longxin Xiong
    • Yongjian Peng
    • Lei Zeng
    • Guofu Huang
  • View Affiliations / Copyright

    Affiliations: Nanchang Key Laboratory of Cancer Pathogenesis and Translational Research, Center Laboratory, The Third Affiliated Hospital, Nanchang University, Nanchang, Jiangxi 330008, P.R. China, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat‑sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China, Respiratory Department, Nanchang Hospital of Integrative Traditional Chinese and Western Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330008, P.R. China, College of Arts and Sciences, Cornell University, Ithaca, NY 14850, USA, Department of Radiation Oncology, The Affiliated Hospital of Guilin Medical University, Guilin, Guangxi 541000, P.R. China, Department of Radiation Oncology, Jiangxi Cancer Hospital, Nanchang, Jiangxi 330029, P.R. China
    Copyright: © Sang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 294-302
    |
    Published online on: October 16, 2018
       https://doi.org/10.3892/ol.2018.9588
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Mortality factor 4‑like 1 (MORF4L1) is a member of a subgroup of histone acetyltransferases and belongs to the mortality factor on chromosome 4 (MORF4) class of proteins. However, the role of MORF4L1 in cancers is largely unknown. Using reverse transcription‑quantitative polymerase chain reaction and published datasets, the present study demonstrated that the expression of MORF4L1 is decreased in several cancers, including nasopharyngeal carcinoma (NPC). Additionally, the methylation rate of the promoter of MORF4L1 was identified to be significantly higher in tumour cells than in normal cells. The ectopic expression of MORF4L1 was also revealed to inhibit cell proliferation, colony formation, migration and invasion in NPC, whereas the knockdown of MORF4L1 promoted cell proliferation, colony formation, migration and invasion. Mechanistically, the present study demonstrated that MORF4L1 functions as a tumour suppressor by increasing p21 and E‑cadherin levels. These findings may be useful novel targets for treating patients with NPC.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

View References

1 

Sang Y, Chen MY, Luo D, Zhang RH, Wang L, Li M, Luo R, Qian CN, Shao JY, Zeng YX and Kang T: TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma. Oncotarget. 6:29240–29253. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Wang L, Sang Y, Tang J, Zhang RH, Luo D, Chen M, Deng WG and Kang T: Down-regulation of prostate stem cell antigen (PSCA) by Slug promotes metastasis in nasopharyngeal carcinoma. J Pathol. 237:411–422. 2015. View Article : Google Scholar : PubMed/NCBI

3 

Sang Y, Wang L, Tang JJ, Zhang MF, Zhang MX, Liu X, Zhang RH, Kang TB and Chen MY: Oncogenic roles of carbonic anhydrase IX in human nasopharyngeal carcinoma. Int J Clin Exp Pathol. 7:2942–2949. 2014.PubMed/NCBI

4 

Chen QY, Wen YF, Guo L, Liu H, Huang PY, Mo HY, Li NW, Xiang YQ, Luo DH, Qiu F, et al: Concurrent chemoradiotherapy vs radiotherapy alone in stage II nasopharyngeal carcinoma: Phase III randomized trial. J Natl Cancer Inst. 103:1761–1770. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Liu X, Lv XB, Wang XP, Sang Y, Xu S, Hu K, Wu M, Liang Y, Liu P, Tang J, et al: MiR-138 suppressed nasopharyngeal carcinoma growth and tumorigenesis by targeting the CCND1 oncogene. Cell Cycle. 11:2495–2506. 2012. View Article : Google Scholar : PubMed/NCBI

6 

Li N, Feng L, Han HQ, Yuan J, Qi XK, Lian YF, Kuang BH, Zhang YC, Deng CC, Zhang HJ, et al: A novel Smac mimetic APG-1387 demonstrates potent antitumor activity in nasopharyngeal carcinoma cells by inducing apoptosis. Cancer Lett. 381:14–22. 2016. View Article : Google Scholar : PubMed/NCBI

7 

Bei JX, Li Y, Jia WH, Feng BJ, Zhou G, Chen LZ, Feng QS, Low HQ, Zhang H, He F, et al: A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. Nat Genet. 42:599–603. 2010. View Article : Google Scholar : PubMed/NCBI

8 

Ye SB, Zhang H, Cai TT, Liu YN, Ni JJ, He J, Peng JY, Chen QY, Mo HY, Jun-Cui, et al: Exosomal miR-24-3p impedes T-cell function by targeting FGF11 and serves as a potential prognostic biomarker for nasopharyngeal carcinoma. J Pathol. 240:329–340. 2016. View Article : Google Scholar : PubMed/NCBI

9 

Wen X, Tang X, Li Y, Ren X, He Q, Yang X, Zhang J, Wang Y, Ma J and Liu N: Microarray expression profiling of long non-coding RNAs involved in nasopharyngeal carcinoma metastasis. Int J Mol Sci. 17:19562016. View Article : Google Scholar

10 

Li W, Li J, Wang Y, Zhang K, Li N, Tian Z, Ni B, Wang H and Ruan Z: Sphingosine kinase 1 is a potential therapeutic target for nasopharyngeal carcinoma. Oncotarget. 7:80586–80598. 2016.PubMed/NCBI

11 

Zhang L, Su B, Sun W, Li W, Luo M, Liu D, Mei Q, Long G and Hu G and Hu G: Twist1 promotes radioresistance in nasopharyngeal carcinoma. Oncotarget. 7:81332–81340. 2016.PubMed/NCBI

12 

Zhang P, Du J, Sun B, Dong X, Xu G, Zhou J, Huang Q, Liu Q, Hao Q and Ding J: Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3. Nucleic Acids Res. 34:6621–6628. 2006. View Article : Google Scholar : PubMed/NCBI

13 

Pardo PS, Leung JK, Lucchesi JC and Pereira-Smith OM: MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation. J Biol Chem. 277:50860–50866. 2002. View Article : Google Scholar : PubMed/NCBI

14 

Bryce SD, Forsyth NR, Fitzsimmons SA, Clark LJ, Bertram MJ, Cuthbert AP, Newbold RF, Pereira-Smith OM and Parkinson EK: Genetic and functional analyses exclude mortality factor 4 (MORF4) as a keratinocyte senescence gene. Cancer Res. 59:2038–2040. 1999.PubMed/NCBI

15 

Yochum GS and Ayer DE: Role for the mortality factors MORF4, MRGX and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split. Mol Cell Biol. 22:7868–7876. 2002. View Article : Google Scholar : PubMed/NCBI

16 

Chen Y, Li J, Dunn S, Xiong S, Chen W, Zhao Y, Chen BB, Mallampalli RK and Zou C: Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization. J Biol Chem. 289:7092–7098. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Tominaga K, Kirtane B, Jackson JG, Ikeno Y, Ikeda T, Hawks C, Smith JR, Matzuk MM and Pereira-Smith OM: MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol. 25:2924–2937. 2005. View Article : Google Scholar : PubMed/NCBI

18 

Zou C, Li J, Xiong S, Chen Y, Wu Q, Li X, Weathington NM, Han S, Snavely C, Chen BB and Mallampalli RK: Mortality factor 4 like 1 protein mediates epithelial cell death in a mouse model of pneumonia. Sci Transl Med. 7:311ra1712015. View Article : Google Scholar : PubMed/NCBI

19 

Liang Y, Lin JC, Wang K, Chen YJ, Liu HH, Luan R, Jiang S, Che T, Zhao Y, Li de F, et al: A nuclear ligand MRG15 involved in the proapoptotic activity of medicinal fungal galectin AAL (Agrocybe aegerita lectin). Biochim Biophys Acta. 1800:474–480. 2010. View Article : Google Scholar : PubMed/NCBI

20 

Garcia SN, Kirtane BM, Podlutsky AJ, Pereira-Smith OM and Tominaga K: Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA-repair defects post exposure to gamma ionizing radiation. FEBS Lett. 581:5275–5281. 2007. View Article : Google Scholar : PubMed/NCBI

21 

Martrat G, Maxwell CM, Tominaga E, Porta-de-la-Riva M, Bonifaci N, Gómez-Baldó L, Bogliolo M, Lázaro C, Blanco I, Brunet J, et al: Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Res. 13:R402011. View Article : Google Scholar : PubMed/NCBI

22 

Yin Y, Zhong J, Li SW, Li JZ, Zhou M, Chen Y, Sang Y and Liu L: TRIM11, a direct target of miR-24-3p, promotes cell proliferation and inhibits apoptosis in colon cancer. Oncotarget. 7:86755–86765. 2016. View Article : Google Scholar : PubMed/NCBI

23 

Lv XB, Liu L, Cheng C, Yu B, Xiong L, Hu K, Tang J, Zeng L and Sang Y: SUN2 exerts tumor suppressor functions by suppressing the Warburg effect in lung cancer. Sci Rep. 5:179402015. View Article : Google Scholar : PubMed/NCBI

24 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar : PubMed/NCBI

25 

Huang WY, Hsu SD, Huang HY, Sun YM, Chou CH, Weng SL and Huang HD: MethHC: A database of DNA methylation and gene expression in human cancer. Nucleic Acids Res. 43:(Database Issue). D856–D861. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Zhang RL, Peng LX, Yang JP, Zheng LS, Xie P, Wang MY, Huang BJ, Zhao HR, Bao YX and Qian CN: IL-8 suppresses E-cadherin expression in nasopharyngeal carcinoma cells by enhancing E-cadherin promoter DNA methylation. Int J Oncol. 48:207–214. 2016. View Article : Google Scholar : PubMed/NCBI

27 

Zhao L, Lin L, Pan C, Shi M, Liao Y, Bin J and Liao W: Flotillin-2 promotes nasopharyngeal carcinoma metastasis and is necessary for the epithelial-mesenchymal transition induced by transforming growth factor-beta. Oncotarget. 6:9781–9793. 2015.PubMed/NCBI

28 

Chen C, Lu Z, Yang J, Hao W, Qin Y, Wang H, Xie C and Xie R: MiR-17-5p promotes cancer cell proliferation and tumorigenesis in nasopharyngeal carcinoma by targeting p21. Cancer Med. 5:3489–3499. 2016. View Article : Google Scholar : PubMed/NCBI

29 

Yi C, Wang Q, Wang L, Huang Y, Li L, Liu L, Zhou X, Xie G, Kang T, Wang H, et al: MiR-663, a microRNA targeting p21(WAF1/CIP1), promotes the proliferation and tumorigenesis of nasopharyngeal carcinoma. Oncogene. 31:4421–4433. 2012. View Article : Google Scholar : PubMed/NCBI

30 

Sang Y, Cheng C, Tang XF, Zhang MF and Lv XB: Hypermethylation of TET1 promoter is a new diagnosic marker for breast cancer metastasis. Asian Pac J Cancer Prev. 16:1197–1200. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Tang B, Li Y, Qi G, Yuan S, Wang Z, Yu S, Li B and He S: Clinicopathological significance of CDKN2A promoter hypermethylation frequency with pancreatic cancer. Sci Rep. 5:135632015. View Article : Google Scholar : PubMed/NCBI

32 

Chen M, Pereira-Smith OM and Tominaga K: Loss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor. Stem Cell Res. 7:75–88. 2011. View Article : Google Scholar : PubMed/NCBI

33 

Chen J, Hao Y, Chen J, Huang L, Ao W, Yang J, Li L, Heng J, Chen Z, Liang W, et al: Colony stimulating factor-1 receptor promotes proliferation, migration and invasion in the human nasopharyngeal carcinoma 6-10B cell line via the phosphoinositide 3-kinase/Akt pathway. Oncol Lett. 16:1205–1211. 2018.PubMed/NCBI

34 

Nie GH, Li Z, Duan HF, Luo L, Hu HY, Yang WQ, Nie LP, Zhu RF, Chen XF and Zhang W: lncRNA C22orf32-1 contributes to the tumorigenesis of nasopharyngeal carcinoma. Oncol Lett. 13:4487–4492. 2017. View Article : Google Scholar : PubMed/NCBI

35 

Yuan Y, Du Y, Hu XY, Liu MY, Du JK, Liu XM, Yu HE, Wang TZ, Pu JX, Zhong Q and Zou QF: Longikaurin A, a natural ent-kaurane, suppresses stemness in nasopharyngeal carcinoma cells. Oncology Lett. 13:1672–1680. 2017. View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Sang Y, Zhang R, Sun L, Chen KK, Li SW, Xiong L, Peng Y, Zeng L and Huang G: MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma. Oncol Lett 17: 294-302, 2019.
APA
Sang, Y., Zhang, R., Sun, L., Chen, K.K., Li, S., Xiong, L. ... Huang, G. (2019). MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma. Oncology Letters, 17, 294-302. https://doi.org/10.3892/ol.2018.9588
MLA
Sang, Y., Zhang, R., Sun, L., Chen, K. K., Li, S., Xiong, L., Peng, Y., Zeng, L., Huang, G."MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma". Oncology Letters 17.1 (2019): 294-302.
Chicago
Sang, Y., Zhang, R., Sun, L., Chen, K. K., Li, S., Xiong, L., Peng, Y., Zeng, L., Huang, G."MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma". Oncology Letters 17, no. 1 (2019): 294-302. https://doi.org/10.3892/ol.2018.9588
Copy and paste a formatted citation
x
Spandidos Publications style
Sang Y, Zhang R, Sun L, Chen KK, Li SW, Xiong L, Peng Y, Zeng L and Huang G: MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma. Oncol Lett 17: 294-302, 2019.
APA
Sang, Y., Zhang, R., Sun, L., Chen, K.K., Li, S., Xiong, L. ... Huang, G. (2019). MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma. Oncology Letters, 17, 294-302. https://doi.org/10.3892/ol.2018.9588
MLA
Sang, Y., Zhang, R., Sun, L., Chen, K. K., Li, S., Xiong, L., Peng, Y., Zeng, L., Huang, G."MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma". Oncology Letters 17.1 (2019): 294-302.
Chicago
Sang, Y., Zhang, R., Sun, L., Chen, K. K., Li, S., Xiong, L., Peng, Y., Zeng, L., Huang, G."MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma". Oncology Letters 17, no. 1 (2019): 294-302. https://doi.org/10.3892/ol.2018.9588
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team