Oncology Letters

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Print ISSN: 1792-1074 Online ISSN: 1792-1082

Oncology Letters

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

January-2019 Volume 17 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Patient‑derived xenograft mouse models: A high fidelity tool for individualized medicine (Review)

Cong Xu, Xuelu Li, Pixu Liu, Man Li, Fuwen Luo

Pages: 3-10
Published online on: 16 October 2018

Review Open Access

Clinical significance of exosomal miRNAs and proteins in three human cancers with high mortality in China (Review)

Li‑Man Li, Huan Liu, Xing‑Hui Liu, Hong‑Bin Hu, Song‑Mei Liu

Pages: 11-22
Published online on: 29 October 2018

Review Open Access

Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and cell migration/invasion (Review)

Ganiou Assani, Yunfeng Zhou

Pages: 23-30
Published online on: 29 October 2018

Review Open Access

Novel role of microRNA‑126 in digestive system cancers: From bench to bedside (Review)

Mingli Hu, Shengwei Xiong, Qiaofeng Chen, Shixuan Zhu, Xiaodong Zhou

Pages: 31-41
Published online on: 29 October 2018

Article Open Access

Effects of different doses of X‑ray irradiation on cell apoptosis, cell cycle, DNA damage repair and glycolysis in HeLa cells

Hong Zhao, Yafei Zhuang, Ruibin Li, Yinyin Liu, Zijie Mei, Zhongshi He, Fuxiang Zhou, Yunfeng Zhou

Pages: 42-54
Published online on: 11 October 2018

Article Open Access

MicroRNA 214 inhibits adipocyte enhancer‑binding protein 1 activity and increases the sensitivity of chemotherapy in colorectal cancer

Shouchao Li, Chengren Li, Zhiming Fang

Pages: 55-62
Published online on: 26 October 2018

Article Open Access

Expression pattern and level of ING5 protein in normal and cancer tissues

Xue‑Feng Yang, Dao‑Fu Shen, Shuang Zhao, Tian‑Ren Ren, Yang Gao, Shuai Shi, Ji‑Cheng Wu, Hong‑Zhi Sun, Hua‑Chuan Zheng

Pages: 63-68
Published online on: 16 October 2018

Article Open Access

A clinical study on the expression of PTEN in renal cell carcinoma in children

Hong Lu, Yuxia Tan, Liping Chen

Pages: 69-72
Published online on: 12 October 2018

Article

MiR‑506 inhibits cell proliferation, invasion, migration and epithelial‑to‑mesenchymal transition through targeting RWDD4 in human bladder cancer

Yi Hou

Pages: 73-78
Published online on: 18 October 2018

Article Open Access

Overexpression of Ulk2 inhibits proliferation and enhances chemosensitivity to cisplatin in non‑small cell lung cancer

Hong Cheng, Ze‑Tian Yang, Yu‑Quan Bai, Yan‑Fei Cai, Jin‑Ping Zhao

Pages: 79-86
Published online on: 22 October 2018

Article

miR‑125a is upregulated in cancer stem‑like cells derived from TW01 and is responsible for maintaining stemness by inhibiting p53

Jianjun Chen, Hui Ouyang, Xuemei An, Shixi Liu

Pages: 87-94
Published online on: 16 October 2018

Article Open Access

Significance of TERT and ATRX mutations in glioma

Jiayu Liu, Xuebin Zhang, Xiaoling Yan, Mei Sun, Yueshan Fan, Ying Huang

Pages: 95-102
Published online on: 29 October 2018

Article Open Access

Downregulation of long noncoding RNA FENDRR predicts poor prognosis in renal cell carcinoma

Wang He, Guangzheng Zhong, Pei Wang, Chun Jiang, Ning Jiang, Jian Huang

Pages: 103-112
Published online on: 26 October 2018

Article Open Access

Basic transcription factor 3 expression silencing attenuates colon cancer cell proliferation and migration in vitro

Xu Li, Jinke Sui, Junjie Xing, Fuao Cao, Hao Wang, Chuangang Fu, Hantao Wang

Pages: 113-118
Published online on: 24 October 2018

Article

Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi

Mengge Li, Yalin Zhao, Xiaoli Liu, Zhibo Dang, Xinhui Wang, Yuyong Jiang, Zhiyun Yang

Pages: 119-126
Published online on: 17 October 2018

Article Open Access

Apoptosis of mouse myeloma cells induced by curcumin via the Notch3‑p53 signaling axis

Ying Zhang, Xin‑Yu Lin, Jiao‑Hui Zhang, Zheng‑Lu Xie, Hui Deng, Yi‑Fang Huang, Xiao‑Hong Huang

Pages: 127-134
Published online on: 17 October 2018

Article Open Access

Downregulation of LPXN expression by siRNA decreases the malignant proliferation and transmembrane invasion of SHI‑1 cells

Guo‑Hua Zhu, Hai‑Ping Dai, Qun Shen, Qi Zhang

Pages: 135-140
Published online on: 22 October 2018

Article Open Access

High expression of density‑regulated re‑initiation and release factor drives tumourigenesis and affects clinical outcome

Dazhi Wang, Lanying Wang, Chunling Ren, Pei Zhang, Mengmeng Wang, Shuyu Zhang

Pages: 141-148
Published online on: 25 October 2018

Article Open Access

18F‑FDG‑PET/CT‑guided intensity‑modulated radiotherapy for 42 FIGO III/IV ovarian cancer: A retrospective study

Ya‑Zheng Dang, Xin Li, Yu‑Xin Ma, Xiao‑Long Li, Ting Yang, Wan‑Ling Lu, Shi‑Gao Huang

Pages: 149-158
Published online on: 19 October 2018

Article Open Access

Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer

Shengbo Tang, Xihong Yuan, Jintian Song, Yigui Chen, Xiaojie Tan, Qiyun Li

Pages: 159-164
Published online on: 12 October 2018

Article Open Access

Prognostic value of inflammation‑based indexes for intrahepatic cholangiocarcinoma following curative resection

Yunhua Wu, Fenggang Ren, Yichao Chai, Zhao Xue, Cong Shen, Xufeng Zhang, Yi Lv, Liangshuo Hu

Pages: 165-174
Published online on: 24 October 2018

Article Open Access

Lentiviral vector‑mediated IL‑9 overexpression stimulates cell proliferation by targeting c‑myc and cyclin D1 in colitis‑associated cancer

Linglin Tian, Yuan Li, Ruqi Chang, Peng Zhang, Jian Zhang, Lijuan Huo

Pages: 175-182
Published online on: 11 October 2018

Article Open Access

Association of BRAF gene and TSHR with cervical lymph node metastasis of papillary thyroid microcarcinoma

Changxin Zhou, Jinbo Li, Yu Wang, Shoukun Xue, Yang Zhang

Pages: 183-194
Published online on: 12 October 2018

Article Open Access

Puerarin in inducing apoptosis of bladder cancer cells through inhibiting SIRT1/p53 pathway

Guomei Ye, Shifeng Kan, Jianfeng Chen, Xin Lu

Pages: 195-200
Published online on: 19 October 2018

Article Open Access

Clinical efficacy and mechanism of Pralatrexate combined with Palbociclib Isethionate in treatment of bladder cancer patients

Xiaobin Wang, Huihan Wang, Yongsheng Song

Pages: 201-208
Published online on: 24 October 2018

Article Open Access

Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer

Qiaohong Pan, Jianwu Ji

Pages: 209-214
Published online on: 17 October 2018

Article Open Access

Clinical effects of high frequency hyperthermia-assisted irinotecan chemotherapy on patients with middle and advanced colorectal cancer and its safety assessment

Zichuan Liu

Pages: 215-220
Published online on: 12 October 2018

Article Open Access

MIR31HG promotes cell proliferation and invasion by activating the Wnt/β‑catenin signaling pathway in non‑small cell lung cancer

Shuaiyu Zheng, Xiaojin Zhang, Xian Wang, Jiyuan Li

Pages: 221-229
Published online on: 23 October 2018

Article Open Access

Investigation of the clinical significance and molecular mechanism of miR‑21‑5p in hepatocellular carcinoma: A systematic review based on 24 studies and bioinformatics investigation

Xiao‑Zhu Zhong, Yun Deng, Gang Chen, Hong Yang

Pages: 230-246
Published online on: 26 October 2018

Article Open Access

Identification of plasma RGS18 and PPBP mRNAs as potential biomarkers for gastric cancer using transcriptome arrays

Chen Su, Hanwei Li, Zheng Peng, Dong Ke, Hanjiang Fu, Xiaofei Zheng

Pages: 247-255
Published online on: 23 October 2018

Article Open Access

Long non‑coding RNA XIST predicts poor prognosis and promotes malignant phenotypes in osteosarcoma

Wei Wang, Huiliang Shen, Guanglei Cao, Jiang Huang

Pages: 256-262
Published online on: 18 October 2018

Article Open Access

FRAIL scale as a predictor of complications and mortality in older patients undergoing reconstructive surgery for non‑melanoma skin cancer

Luigi Valdatta, Gianpaolo Perletti, Francesca Maggiulli, Federico Tamborini, Igor Pellegatta, Mario Cherubino

Pages: 263-269
Published online on: 11 October 2018

Article Open Access

Gadofosveset‑enhanced MRI as simple surrogate parameter for real‑time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF‑NGR

Anna Höink, Thorsten Persigehl, Robert Kwiecien, Martin Balthasar, Rolf Mesters, Wolfgang Berdel, Walter Heindel, Christoph Bremer, Christian Schwöppe

Pages: 270-280
Published online on: 29 October 2018

Case Report Open Access

Clinicopathological features of primary thyroid leiomyosarcoma without Epstein‑Barr virus infection: A case report

Jianguo Wei, Jianfeng Yang, Wenqing Liang, Chunwei Xu, Yuanyuan Wen

Pages: 281-287
Published online on: 23 October 2018

Article Open Access

Knockdown of DNA/RNA‑binding protein KIN17 promotes apoptosis of triple‑negative breast cancer cells

Xiang Gao, Zhenping Liu, Meifeng Zhong, Kunhe Wu, Yuzhao Zhang, Hongmei Wang, Tao Zeng

Pages: 288-293
Published online on: 18 October 2018

Article Open Access

MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma

Yi Sang, Ruhua Zhang, Longhua Sun, Kaddie Kwok Chen, Si‑Wei Li, Longxin Xiong, Yongjian Peng, Lei Zeng, Guofu Huang

Pages: 294-302
Published online on: 16 October 2018

Article Open Access

Cistanche tubulosa phenylethanoid glycosides induce apoptosis in Eca‑109 cells via the mitochondria‑dependent pathway

Changshuang Fu, Jinyu Li, Adila Aipire, Lijie Xia, Yi Yang, Qiuyan Chen, Jie Lv, Xinhui Wang, Jinyao Li

Pages: 303-313
Published online on: 29 October 2018

Article Open Access

Ferritin: A potential serum marker for lymph node metastasis in head and neck squamous cell carcinoma

Zhangwei Hu, Lei Wang, Yong Han, Fen Li, Anyuan Zheng, Yong Xu, Fei Wang, Bokui Xiao, Chen Chen, Zezhang Tao

Pages: 314-322
Published online on: 30 October 2018

Article Open Access

Exosomes derived from HBV‑associated liver cancer promote chemoresistance by upregulating chaperone‑mediated autophagy

Dian‑Xing Liu, Peng‑Peng Li, Jia‑Pei Guo, Lei‑Lei Li, Bin Guo, Hong‑Bin Jiao, Jing‑Hua Wu, Jun‑Mao Chen

Pages: 323-331
Published online on: 16 October 2018

Article Open Access

Correlation between microsatellite instability and RAS gene mutation and stage Ⅲ colorectal cancer

Wenbo Niu, Guiying Wang, Jun Feng, Zheng Li, Chenhui Li, Baoen Shan

Pages: 332-338
Published online on: 23 October 2018

Article Open Access

Effects of complement and serum IgG on rituximab‑dependent natural killer cell‑mediated cytotoxicity against Raji cells

Yang Li, Ke Huang, Ling Liu, Yuhua Qu, Yan Huang, Yanfeng Wu, Jing Wei

Pages: 339-347
Published online on: 29 October 2018

Article Open Access

Analysis of the inhibitory effects of miR‑124 and miR-152 on human epithelial ovarian cancer xenografts in a nude mouse model

Weiwei Liu, Lixia Zhang, Jing Wang, Xiaoli Wang, Hong Sun

Pages: 348-354
Published online on: 24 October 2018

Article Open Access

Values of thoracic contrast‑enhanced computed tomography in detecting incidental pulmonary thromboembolism in patients with malignant tumors

Lijuan Dai, Gaofeng Shi, Yang Li, Bo Zhao

Pages: 355-359
Published online on: 15 October 2018

Article Open Access

A hybrid technique for treating multilevel cervical myelopathy: Cervical artificial disc replacement combined with fusion

Yunrong Zhu, Jianfeng Fang, Guohua Xu, Xiaojian Ye, Yunqing Zhang

Pages: 360-364
Published online on: 12 October 2018

Article Open Access

MicroRNA‑24‑3p regulates Hodgkin's lymphoma cell proliferation, migration and invasion by targeting DEDD

Jing Wang, Kai Yin, Xianping Lv, Qiankun Yang, Ming Shao, Xin Liu, Hui Sun

Pages: 365-371
Published online on: 19 October 2018

Article Open Access

miR-149-5p inhibits cell proliferation and invasion through targeting GIT1 in medullary thyroid carcinoma

Xiaojuan Ye, Xiaofang Chen

Pages: 372-378
Published online on: 26 October 2018

Article

Transgenic overexpression of human LY6K in mice suppresses mature T cell development in the thymus

Dasom Son, Hyun-Kyung Kong, Yesol Kim, Min-Ji Song, Hyong Pyo Kim, Han Woong Lee, Jong Hoon Park

Pages: 379-387
Published online on: 04 October 2018

Article

circRNA of AR‑suppressed PABPC1 91 bp enhances the cytotoxicity of natural killer cells against hepatocellular carcinoma via upregulating UL16 binding protein 1

Yuanming Ma, Chunjun Zhang, Bo Zhang, Haibo Yu, Qingsong Yu

Pages: 388-397
Published online on: 22 October 2018

Article

Increased serum levels of miR‑214 in patients with PCa with bone metastasis may serve as a potential biomarker by targeting PTEN

Yi Fang, Jun Qiu, Zong‑Bin Jiang, Sheng‑Rong Xu, Zeng‑Hua Zhou, Rui‑Lin He

Pages: 398-405
Published online on: 28 September 2018

Article

miR‑30a regulates the proliferation and invasion of breast cancer cells by targeting Snail

Baoqiang Xiao, Xuejing Shi, Jianping Bai

Pages: 406-413
Published online on: 05 October 2018

Article

Silencing of miR‑19a‑3p enhances osteosarcoma cells chemosensitivity by elevating the expression of tumor suppressor PTEN

Bo Zhang, Yuan Liu, Jiangnan Zhang

Pages: 414-421
Published online on: 17 October 2018

Article

Su Yang Decoction induces human colon carcinoma cell apoptosis by activating caspases

Yazhong Ge, Qing Gao, Fengjiao Yan, Xiaona Zhang, Yurong Liu, Yi Zhou

Pages: 422-431
Published online on: 26 October 2018

Article

Identification of prognostic genes in colorectal cancer through transcription profiling of multi‑stage carcinogenesis

Ning An, Chen Zhao, Zhuang Yu, Xue Yang

Pages: 432-441
Published online on: 29 October 2018

Article

Cancer stem cell associated eight gene‑based signature predicts clinical outcomes of colorectal cancer

Chuanpeng Dong, Danni Cui, Gang Liu, Huilin Xu, Xueqing Peng, Juan Duan, Lei Liu

Pages: 442-449
Published online on: 01 October 2018

Article

Effects of tanshinones mediated by forkhead box O3a transcription factor on the proliferation and apoptosis of lung cancer cells

Dongjie Liu, Renbing Yuan, Fang Yang, Dehui Zhang

Pages: 450-455
Published online on: 01 October 2018

Article

Norcantharidin inhibits viability and induces cell cycle arrest and apoptosis in osteosarcoma

Yingchun Zhu, Yunfeng Mi, Zheyang Wang, Xuewen Jia, Zhanping Jin

Pages: 456-461
Published online on: 24 October 2018

Case Report

Urothelial bladder carcinoma metastasizing to the eye: A systematic review and case report

Guido Giordano, Nunzio Olivieri, Mario Rosario D'Andrea, Tania Di Raimo, Erminia Manfrin, Andrea Remo, Massimo Pancione, Matteo Brunelli, Elena De Santis, Giulia Coppola, Aldo Scarpa, Luigi Coppola, Pietro Parcesepe

Pages: 462-467
Published online on: 15 October 2018

Article

Identification of core genes and prediction of miRNAs associated with osteoporosis using a bioinformatics approach

Yi Chai, Feng Tan, Sumin Ye, Feixiang Liu, Qiaoling Fan

Pages: 468-481
Published online on: 26 September 2018

Article

Forkhead box O1 as an indicator of prognosis is inactivated in urothelial carcinoma of the upper urinary tract

Hiroki Ide, Guiyang Jiang, Taichi Mizushima, Kazutoshi Fujita, Satoshi Inoue, Seiji Yamaguchi, Hiroaki Fushimi, Norio Nonomura, Hiroshi Miyamoto

Pages: 482-487
Published online on: 26 September 2018

Case Report

ROS1‑rearranged high‑PD‑L1‑expressing lung adenocarcinoma manifesting as mediastinal tumor: A case report

Hiroyuki Ogawa, Yugo Tanaka, Motoko Tachihara, Keiichiro Uehara, Nahoko Shimizu, Takefumi Doi, Daisuke Hokka, Yoshimasa Maniwa

Pages: 488-491
Published online on: 25 October 2018

Article

Identification of potential genes and pathways for response prediction of neoadjuvant chemoradiotherapy in patients with rectal cancer by systemic biological analysis

Qiliang Peng, Kaisu Lin, Yi Shen, Ping Zhou, Shaonan Fan, Yuntian Shen, Yaqun Zhu

Pages: 492-501
Published online on: 18 October 2018

Article

Clinical significance of reduced GPRC5A expression in surgically resected non‑small cell lung cancer

Er Jin, Wenzhe Wang, Mengdie Fang, Wei Wang, Ruifei Xie, Hong Zhou, Jian Ye, Rujun Xu, Shenglin Ma

Pages: 502-507
Published online on: 02 October 2018

Article

Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma

Lijian Gao, Hongda Zhao, Dongqing Zhang, Changkuo Zhou, Hui Wang, Chantao Ren, Yaxiao Liu, Yangyang Xia, Benkang Shi

Pages: 508-513
Published online on: 15 October 2018

Case Report

Glomus tumor of the stomach treated by laparoscopic distal gastrectomy: A case report

Tsutomu Namikawa, Sachi Tsuda, Kazune Fujisawa, Jun Iwabu, Sunao Uemura, Shigehiro Tsujii, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazaki

Pages: 514-517
Published online on: 25 October 2018

Article

Use of ANGPTL2 mRNA levels in formalin‑fixed paraffin‑embedded tissues as a biomarker to diagnose gastric cancer and to evaluate the extent of vascular invasion

Takuma Yoshinaga, Hiroto Nishimata, Sadao Tanaka, Emiko Hori, Ayako Tomiyoshi, Erena Tokudome, Takayuki Takei, Masahiro Yoshida

Pages: 518-524
Published online on: 23 October 2018

Article

Lentiviral RNA interference‑mediated downregulation of Forkhead box M1 expression suppresses growth of oral squamous cell carcinoma in vitro

Jing Qiu, Juan Zhao, Anjun Zuo, Lan Liu, Qiaoqiao Liu, Huazheng Pan, Xiao Yuan

Pages: 525-531
Published online on: 02 October 2018

Article

Müllerian inhibiting substance/anti‑Müllerian hormone type II receptor protein and mRNA expression in the healthy and cancerous endometria

Su Mi Kim, Yun Oh Kim, Min Kyoung Lee, Youn Jee Chung, In Cheul Jeung, Mee Ran Kim, Jang Heub Kim

Pages: 532-538
Published online on: 10 October 2018

Article

Characterizing the landscape of peritoneal exosomal microRNAs in patients with ovarian cancer by high‑throughput sequencing

Yuankun Li, Cuihua Liu, Yumei Liao, Wuliang Wang, Bin Hu, Xiaoqin Lu, Jinquan Cui

Pages: 539-547
Published online on: 09 October 2018

Article

MicroRNA‑183 inhibits A375 human melanoma cell migration and invasion by targeting Ezrin and MMP‑9

Yusen Zhang, Guoqiang Wang

Pages: 548-554
Published online on: 22 October 2018

Article

NANOGP8 expression regulates gastric cancer cell progression by transactivating DBC1 in gastric cancer MKN‑45 cells

Li Li, Ru Feng, Sujuan Fei, Jiang Cao, Qinqin Zhu, Guozhong Ji, Jianwei Zhou

Pages: 555-563
Published online on: 18 October 2018

Article

Capn4 regulates migration and invasion of ovarian carcinoma cells via targeting osteopontin‑mediated PI3K/AKT signaling pathway

Yuanyuan Chen, Gang Wang, Yingmei Wang, Xiaoli Gao, Kan Wang, Jie Li, Fengxia Xue

Pages: 564-570
Published online on: 28 September 2018

Article

miR‑218 suppresses the proliferation of osteosarcoma through downregulation of E2F2

Chengmin Xuan, Mingwei Jin, Yong Gao, Shumei Xu, Lei Wang, Yuan Wang, Rui Han, Qi An

Pages: 571-577
Published online on: 15 October 2018

Article

Carcinosarcoma of the esophagus: A report of 6 cases associated with zinc finger E‑box‑binding homeobox 1 expression

Hiroki Harada, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Marie Washio, Mariko Kikuchi, Yoshimasa Kosaka, Masahiko Watanabe, Keishi Yamashita

Pages: 578-586
Published online on: 16 October 2018

Article

An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma

Rei Suzuki, Tadayuki Takagi, Takuto Hikichi, Mitsuru Sugimoto, Naoki Konno, Hiroyuki Asama, Ko Watanabe, Jun Nakamura, Shigeru Marubashi, Hiromasa Ohira

Pages: 587-593
Published online on: 26 October 2018

Article

Nedaplatin‑based chemotherapy regimens combined with concurrent radiotherapy as first‑line treatment for stage II‑III esophageal squamous cell carcinoma

Huiping Zhu, Xiaolin Ge, Yufeng Lu, Yun Zuo, Qin Qin, Xinchen Sun, Min Yang

Pages: 594-602
Published online on: 10 October 2018

Article

Synergistic action of microwave‑induced mild hyperthermia and paclitaxel in inducing apoptosis in the human breast cancer cell line MCF‑7

Sina Liao, Xiaohua Hu, Zhihui Liu, Yan Lin, Rong Liang, Yumei Zhang, Qian Li, Yongqiang Li, Xiaoli Liao

Pages: 603-615
Published online on: 29 October 2018

Article

Ki‑67 index value and progesterone receptor status can predict prognosis and suitable treatment in node‑negative breast cancer patients with estrogen receptor‑positive and HER2‑negative tumors

Nobuyuki Arima, Reiki Nishimura, Tomofumi Osako, Yasuhiro Okumura, Masahiro Nakano, Mamiko Fujisue, Yasuyuki Nishiyama, Yasuo Toyozumi

Pages: 616-622
Published online on: 29 October 2018

Article

Genetic influence of cytokine polymorphisms on the clinical outcome of Japanese gastrointestinal cancer patients in palliative care

Asahi Hishida, Yoshinaga Okugawa, Yuhki Morimoto, Yumiko Shirai, Kyoko Okamoto, Sachiko Momokita, Aki Ogawa, Koji Tanaka, Ryutaro Nishikawa, Yuji Toiyama, Yasuhiro Inoue, Hiroyuki Sakurai, Hisashi Urata, Motoyoshi Tanaka, Donald C. McMillan, Chikao Miki

Pages: 623-629
Published online on: 24 October 2018

Article

Rotundic acid induces Cas3‑MCF‑7 cell apoptosis through the p53 pathway

Min‑Lun Nan, Xue Wang, Hai‑Jun Li, De‑Hai Yu, Wen‑Yi Sun, Hong‑Mei Xu, Yu‑Fang He, Quan‑Cheng Zhao

Pages: 630-637
Published online on: 24 October 2018

Article

Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A

John Chun‑Hao Chen, Hui‑Yen Chuang, Yi‑Jen Liao, Fei‑Ting Hsu, Yen‑Chung Chen, Wei‑Hsun Wang, Jeng‑Jong Hwang

Pages: 638-645
Published online on: 16 October 2018

Article

MicroRNA‑153 affects nasopharyngeal cancer cell viability by targeting TGF‑β2

Guangliang Guo, Ying Zhang, Limin Hu, Xue Bian

Pages: 646-651
Published online on: 12 October 2018

Article

Upregulation of TMEFF2 is involved in the antiproliferative effects of vitamin C and tyrphostin AG490 on GES‑1 and AGS cells

Hongchao Han, Jie Xu, Weiwei Ji, Lisheng Wang, Aikun Wang

Pages: 652-659
Published online on: 25 October 2018

Article

Trichostatin A induces p53‑dependent endoplasmic reticulum stress in human colon cancer cells

Limeng Dai, Gang He, Kun Zhang, Xingying Guan, Yan Wang, Bo Zhang

Pages: 660-667
Published online on: 30 October 2018

Article

Association between circadian and chemotherapeutic cycle effects on plasma concentration of 5‑fluorouracil and the clinical outcome following definitive 5‑fluorouracil/cisplatin‑based chemoradiotherapy in patients with esophageal squamous cell carcinoma

Akiko Kuwahara, Shinji Kobuchi, Takao Tamura

Pages: 668-675
Published online on: 16 October 2018

Article

Rhamnetin induces apoptosis in human breast cancer cells via the miR‑34a/Notch‑1 signaling pathway

Lan Lan, Yue Wang, Zhanyu Pan, Bin Wang, Zhensong Yue, Zhansheng Jiang, Ling Li, Cong Wang, Hongmei Tang

Pages: 676-682
Published online on: 15 October 2018

Article

Evaluation of the cytotoxic effect of Ly2109761 on HeLa cells using the xCELLigence RTCA system

İdi̇l Çeti̇n, Mehmet R. Topçul

Pages: 683-687
Published online on: 09 October 2018

Article

MicroRNA‑342‑3p functions as a tumor suppressor by targeting LIM and SH3 protein 1 in oral squamous cell carcinoma

Xiaoyan Song, Yong Jin, Mingyu Yan, Yonggang Zhang, Bing Chen

Pages: 688-696
Published online on: 29 October 2018

Article

Resveratrol integrates metabolic and growth effects in PC3 prostate cancer cells‑involvement of prolyl hydroxylase and hypoxia inducible factor‑1

Joao Fonseca, Fereshteh Moradi, Lucas A. Maddalena, Bruna Ferreira‑Tollstadius, Shehab Selim, Jeffrey A. Stuart

Pages: 697-705
Published online on: 28 September 2018

Article

miR‑34a inhibits esophageal squamous cell carcinoma progression via regulation of FOXM1

Haibo Zhou, Li Yang, Xinhua Xu, Mingqian Lu, Rong Guo, Daojun Li, Qiao Huang, Yang Liu, Glenn Deng, Yalin Xu

Pages: 706-712
Published online on: 17 October 2018

Article

Anticancer activity and phytochemical composition of wild Gundelia tournefortii

Saleh Abu‑Lafi, Baraa Rayan, Sleman Kadan, Malek Abu‑Lafi, Anwar Rayan

Pages: 713-717
Published online on: 19 October 2018

Correction Open Access

[Erratum] Prognostic value of heterogeneous ribonucleoprotein A1 expression and inflammatory indicators for patients with surgically resected hepatocellular carcinoma: Perspectives from a high occurrence area of hepatocellular carcinoma in China

Ruisheng Ke, Lizhi Lv, Jiayan Li, Xiaojin Zhang, Fang Yang, Kun Zhang, Yi Jiang

Pages: 718-718
Published online on: 15 October 2018

Retraction Open Access

[Retracted] Effect of galectin‑3 on vasculogenic mimicry in esophageal cancer cells

Jingxin Zhang, Guodong Deng, Lili Qiao, Hui Luo, Qiqi Liu, Ning Liang, Jian Xie, Jiandong Zhang

Pages: 719-719
Published online on: 30 October 2018

Review

Sirtuin 1 and oral cancer (Review)

Shajedul Islam, Yoshihiro Abiko, Osamu Uehara, Itsuo Chiba

Pages: 729-738
Published online on: 16 November 2018

Article Open Access

Fibrinogen is associated with EGFR mutation status and lymphatic metastasis in non‑small cell lung cancer

Jian Guan, Nan Xiao, Chun Qiu, Qin Li, Min Chen, Yao Zhang, Yong Dai, Lu Li, Yue Zhang, Mi Yang, Long Chen, Lai Yu Liu

Pages: 739-746
Published online on: 01 November 2018

Article Open Access

Macrophages activate mesenchymal stem cells to acquire cancer‑associated fibroblast‑like features resulting in gastric epithelial cell lesions and malignant transformation in vitro

Qiang Zhang, Shuo Chai, Wei Wang, Chengcheng Wan, Feng Zhang, Yuyun Li, Fengchao Wang

Pages: 747-756
Published online on: 15 November 2018

Article Open Access

JS‑K enhances chemosensitivity of prostate cancer cells to Taxol via reactive oxygen species activation

Mingning Qiu, Sai Zhang, Longzhi Ke, Huancheng Tang, Xin Zeng, Jianjun Liu

Pages: 757-764
Published online on: 09 November 2018

Article Open Access

Knockdown of CHCHD2 inhibits migration and angiogenesis of human renal cell carcinoma: A potential molecular marker for treatment of RCC

Qian Cheng, Debao Qu, Zheng Lu, Longzhen Zhang

Pages: 765-772
Published online on: 12 November 2018

Article Open Access

AKR1B10 expression predicts response of gastric cancer to neoadjuvant chemotherapy

Syed Minhaj Uddin Ahmed, Zi Nong Jiang, Zhao Hong Zheng, Yulong Li, Xiu Jun Wang, Xiuwen Tang

Pages: 773-780
Published online on: 15 November 2018

Article Open Access

MicroRNA‑525 enhances chondrosarcoma malignancy by targeting F‑spondin 1 Retraction in /10.3892/ol.2024.14676

Bo Liu, Xiandong Song, Zhaowei Yan, Hao Yang, Yingchao Shi, Jintao Wu

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Ping Chen, Qi Zhong, Zufei Li, Yang Zhang, Zhigang Huang

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Wei Wang, Ying He, Jing Rui, Mao‑Qi Xu

Pages: 807-814
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Inhibition of colorectal cancer liver metastasis in BALB/c mice following intratumoral injection of oncolytic herpes simplex virus type 2 for the induction of specific antitumor immunity

Wen Zhang, Feifei Wang, Xiao Hu, Jing Liang, Binlei Liu, Qi Guan, Shangmei Liu

Pages: 815-822
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A case of intrahepatic cholangiocarcinoma that was difficult to diagnose prior to surgery: A case report

Ken Nagata, Takahiro Einama, Akifumi Kimura, Michinori Murayama, Hiroteru Takeo, Makoto Nishikawa, Mayumi Hoshikawa, Takuji Noro, Sho Ogata, Suefumi Aosasa, Yoshiki Kajiwara, Eiji Shinto, Yoshihisa Yaguchi, Shuichi Hiraki, Hironori Tsujimoto, Kazuo Hase, Hideki Ueno, Junji Yamamoto

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Takao Iemoto, Shin Nishiumi, Takashi Kobayashi, Seiji Fujigaki, Tetsuya Hamaguchi, Ken Kato, Hirokazu Shoji, Yasuhiro Matsumura, Kazufumi Honda, Masaru Yoshida

Pages: 831-842
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miR‑205 targets runt‑related transcription factor 2 to inhibit human pancreatic cancer progression

Lu Zhuang, Jia Guo, Yao Yao, Zhaoshen Li

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Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma

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Wei Xu, Xiaogai Qi, Xia Wang, Jize Sun

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Zhengfeng Xu, Jiajun Wu, Pan Cai, Xiaoxiao Zhou, Cunguo Yi, Bin Wang

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miR-29 promotes osteosarcoma cell proliferation and migration by targeting PTEN

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Guozhang Hu, Wei Fang, Naijie Liu, Chang Li

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Identification of key pathways and genes in endometrial cancer using bioinformatics analyses

Yan Liu, Teng Hua, Shuqi Chi, Hongbo Wang

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Efficacy and safety of TE/TEC/intensive paclitaxel neoadjuvant chemotherapy for the treatment of breast cancer

Yang Liu, Zhaoguo Xu, Zhenyong Zhang, Guangfu Wen, Jiaxing Sun, Feng Han

Pages: 907-912
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Masakazu Yoneda, Ryuji Imamura, Hidetoshi Nitta, Keisuke Taniguchi, Fumitaka Saito, Ken Kikuchi, Hidenao Ogi, Takuya Tanaka, Hidetaka Katabuchi, Hideki Nakayama, Takahisa Imamura

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Yasuyuki Kanke, Motonobu Saito, Noriko Abe, Katsuharu Saito, Akiteru Goto, Tohru Ohtake, Yoshinori Murakami, Koji Kono

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Cytokeratin expression in epidermal stem cells in skin adnexal tumors

Xiaoqiu Zhou, Guoyong Li, Dongguan Wang, Xiyin Sun, Xingong Li

Pages: 927-932
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Honghu Xie, Qicheng Lu, Haitao Wang, Xianbo Zhu, Zhong Guan

Pages: 933-936
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Sirtuin‑7 knockdown inhibits the growth of endometrial cancer cells by inducing apoptosis via the NF‑κB signaling pathway

Shiqin Mao, Jimin Ma, Hong Yu

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Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen

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SNHG20 serves as a predictor for prognosis and promotes cell growth in oral squamous cell carcinoma

Pengjie Gao, Rui Fan, Tao Ge

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Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity

Na Qin, Fengli Han, Li Li, Yingwei Ge, Wei Lin, Jiang Wang, Lin Wu, Gang Zhao, Yanchun Deng, Jian Zhang

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Ginsenoside Rg3 inhibits the migration and invasion of liver cancer cells by increasing the protein expression of ARHGAP9

Meng‑Yao Sun, Ya‑Nan Song, Miao Zhang, Chun‑Yan Zhang, Li‑Jun Zhang, Hong Zhang

Pages: 965-973
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Ki‑67 is an independent prognostic marker for the recurrence and relapse of oral squamous cell carcinoma

Yue Jing, Qian Zhou, Huidong Zhu, Ye Zhang, Yuxian Song, Xiaoxin Zhang, Xiaofeng Huang, Yan Yang, Yanhong Ni, Qingang Hu

Pages: 974-980
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Local suture ligation‑assisted percutaneous sclerotherapy for Kasabach‑Merritt phenomenon‑associated kaposiform haemangioendothelioma

Xiao Li, Ming‑Zhe Wen, Li‑Xin Su, Xi‑Tao Yang, Yi‑Feng Han, Xin‑Dong Fan

Pages: 981-989
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miR‑1207‑5p regulates the sensitivity of triple‑negative breast cancer cells to Taxol treatment via the suppression of LZTS1 expression

Xiaoke Hou, Zhaofeng Niu, Leilei Liu, Qiang Guo, Haiyang Li, Xiaojun Yang, Xia Zhang

Pages: 990-998
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Bone mesenchymal stromal cells exhibit functional inhibition but no chromosomal aberrations in chronic myelogenous leukemia

Jieqiong Xie, Jiadi Chen, Bin Wang, Xuchun He, Huifang Huang

Pages: 999-1007
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Anti‑neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells via the regulation of YAP

Wenjing He, Yaodong You, Suya Du, Tiantian Lei, Hailian Wang, Xiang Li, Xia He, Rongsheng Tong, Yi Wang

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Association between NF-κB expression and drug resistance of liver cancer

Tao Liu, Rendong Wei, Yiting Zhang, Wen Chen, Haidong Liu

Pages: 1030-1034
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Identification of hub genes and pathways in glioblastoma by bioinformatics analysis

Shoubo Yang, Kaidi Gao, Wenbin Li

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Case Report Open Access

Ex situ hepatectomy and liver autotransplantation for a treating giant solitary fibrous tumor: A case report

Zhongquan Sun, Yuan Ding, Yuancong Jiang, Qiyi Zhang, Zhiwei Li, Jie Xiang, Jixuan Duan, Sheng Yan, Weilin Wang

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Low‑density lipoprotein promotes lymphatic metastasis of esophageal squamous cell carcinoma and is an adverse prognostic factor

Hongbin Deng, Tao Zhou, Xinkai Mo, Chengxin Liu, Yong Yin

Pages: 1053-1061
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Correlation between tumor microenvironment‑associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer

Siyu Zhang, Wenqi Bai, Xunan Tong, Peng Bu, Jing Xu, Yanfeng Xi

Pages: 1062-1070
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p53‑independent role of MYC mutant T58A in the proliferation and apoptosis of breast cancer cells

Dandan Jiang, Yuhua Song, Weihong Cao, Xingang Wang, Danni Jiang, Zhidong Lv, Zhaochuan Yang, Funian Li

Pages: 1071-1079
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Identification of dysregulated microRNAs in canine malignant melanoma

Norio Ushio, Md Mahfuzur Rahman, Tadashi Maemura, Yu‑Chang Lai, Tomoko Iwanaga, Hiroaki Kawaguchi, Noriaki Miyoshi, Yasuyuki Momoi, Naoki Miura

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Lili Yang, Shuquan Zhang, Rui Gu, Chuangang Peng, Minfei Wu

Pages: 1089-1093
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HNF1B expression regulates ECI2 gene expression, potentially serving a role in prostate cancer progression

Chao Dan, Haiyan Zhang, Wenjing Zeng, Li Huang, Xiaoxin Gong, Hao Li, Erjiang Yang, Li Wang, Qisheng Yao

Pages: 1094-1100
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Perineural invasion as a prognostic risk factor in patients with early cervical cancer

Mei Tang, Qiuli Liu, Xueqing Yang, Ling Chen, Jinjin Yu, Xiaowei Qi, Yuan Wang

Pages: 1101-1107
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Curcumin‑induced promoter hypermethylation of the mammalian target of rapamycin gene in multiple myeloma cells

Jiaqi Chen, Yongli Ying, Hongjun Zhu, Tingjun Zhu, Chunsheng Qu, Jinhong Jiang, Bingmu Fang

Pages: 1108-1114
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Intestinal bacteria detected in cancer and adjacent tissue from patients with colorectal cancer

Chen‑Jian Liu, Yuan‑Lian Zhang, Yun Shang, Bian Wu, En Yang, Yi‑Yong Luo, Xiao‑Ran Li

Pages: 1115-1127
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Association and clinical implication of the USP10 and MSH2 proteins in non‑small cell lung cancer

Zhi Zeng, Dan Li, Tao Yu, Yabing Huang, Honglin Yan, Lijuan Gu, Jingping Yuan

Pages: 1128-1138
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Ginsenoside Rg3 suppresses the proliferation of prostate cancer cell line PC3 through ROS‑induced cell cycle arrest

Yanfei Peng, Ran Zhang, Xu Yang, Zhaiyi Zhang, Ning Kang, Liying Bao, Yongmei Shen, Hao Yan, Fang Zheng

Pages: 1139-1145
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Sperm‑associated antigen 5 is a potential biomarker for poor prognosis in breast cancer

Xiaoli Zhou, Lizhou Jia, Yangyang Sun, Lingyun Xu, Xudong Wang, Qi Tang

Pages: 1146-1152
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Occurrence of senescence-escaping cells in doxorubicin-induced senescence is enhanced by PD0332991, a cyclin-dependent kinase 4/6 inhibitor, in colon cancer HCT116 cells

Kunio Kitada, Fengling Pu, Masakazu Toi

Pages: 1153-1159
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Bo Fan, Sifeng Shi, Xiaofei Shen, Xiaolong Yang, Na Liu, Guixia Wu, Xiaojuan Guo, Ning Huang

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Aikun Ding, Cuiyun Wang, Lihua Zhang

Pages: 1167-1171
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MicroRNA‑183 and microRNA‑141 are potential risk factors for poor prognosis in patients with nasopharyngeal carcinoma

Junsheng Lian, Yujie Li, Min Yu

Pages: 1172-1176
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Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen‑activated protein kinase signaling pathway

Peng Yin, Nanxin Zheng, Junfeng Dong, Chunyang Xu, Xiaomei Zhang, Guoshan Ding

Pages: 1177-1183
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Comparison of values of CT and MRI imaging in the diagnosis of hepatocellular carcinoma and analysis of prognostic factors

Guibin Wang, Shicai Zhu, Xiukui Li

Pages: 1184-1188
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MicroRNA-153 suppresses cell invasion by targeting SNAI1 and predicts patient prognosis in glioma

Wei Zhao, Chang-You Yin, Jing Jiang, Wei Kong, Hao Xu, Hongtao Zhang

Pages: 1189-1195
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Article

Modern approaches to noninvasive diagnosis of malignant transformation of endometriosis

Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto

Pages: 1196-1202
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Article

Systemic transduction of p16INK4a antitumor peptide inhibits lung metastasis of the MBT‑2 bladder tumor cell line in mice

Toru Shimazui, Kazuhiro Yoshikawa, Ryutaro Ishitsuka, Takahiro Kojima, Shuya Kandori, Takayuki Yoshino, Jun Miyazaki, Kazuhiko Uchida, Hiroyuki Nishiyama

Pages: 1203-1210
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Article

Cancerous inhibitor of protein phosphatase 2A regulates cisplatin resistance in ovarian cancer

Wanbin Li, Hongyan Zhang, Linqing Yang, Yunfei Wang

Pages: 1211-1216
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Article

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Rui Wang, Junhai Wang, Tianfu Dong, Jun Shen, Xitao Gao, Jun Zhou

Pages: 1217-1222
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Article

Deletion of C9orf53 promotes the growth of head and neck squamous cell carcinoma and is associated with poor prognosis of patients with head and neck squamous cell carcinoma

Guo Dong Wang, Jian Tao Huang, Yuan Liu, Yang Wu, Xiao Qing Chen, Yun Fu Zhao, Da Lin Wang

Pages: 1223-1228
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Article

Long non‑coding RNA MIAT competitively binds miR‑150‑5p to regulate ZEB1 expression in osteosarcoma

Hao Jin, Xin Jin, Weiguang Chai, Zhiqiang Yin, Yang Li, Feng Dong, Wenbo Wang

Pages: 1229-1236
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Article

SIRT6 inhibits proliferation and invasion in osteosarcoma cells by targeting N‑cadherin

Yi Gao, Yuxing Qu, Qi Zhou, Yong Ma

Pages: 1237-1244
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Article

Oxygen‑laden mesenchymal stem cells enhance the effect of gastric cancer chemotherapy in vitro

Ya‑Li Zhou, Yu‑Min Li, Wen‑Ting He

Pages: 1245-1252
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Case Report

The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report

Vittorio D'Aguanno, Massimo Ralli, Armando De Virgilio, Antonio Greco, Marco de Vincentiis

Pages: 1253-1256
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Article

Critical relevance of genomic gains of PRL‑3/EGFR/c‑myc pathway genes in liver metastasis of colorectal cancer

Toshimichi Tanaka, Takeshi Kaida, Keigo Yokoi, Satoru Ishii, Nobuyuki Nishizawa, Hiroshi Kawamata, Hiroshi Katoh, Takeo Sato, Takatoshi Nakamura, Masahiko Watanabe, Keishi Yamashita

Pages: 1257-1266
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Article

Inhibition effects of Yuxiao San combined with cisplatin on transplanted tumor growths via upregulation of nm‑23 and downregulation of K‑ras in Lewis lung cancer mice

Mo Tang, Shumei Wang, Yulin Wei, Jianti Fu

Pages: 1267-1273
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Article

Intraocular schwannoma: A case series of 3 patients

Yang Yu, Yong Cheng, Kai Wang, Kunkun Sun, Danhua Shen, Jianhong Liang

Pages: 1274-1278
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Article

Comprehensive bioinformatics analysis of lncRNAs in gastric cancer

Dongdong Qi, Qiang Wang, Meiqing Wu, Xiong Zhang

Pages: 1279-1291
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Article

Periostin serves an important role in the pathogenesis of oral squamous cell carcinoma

Yuanyuan Kang, Xue Wang, Ying Zhang, Yan Sun

Pages: 1292-1298
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Article

Comparison of the 8th union for international cancer control lymph node staging system for gastric cancer with two other lymph node staging systems

Huihua Cao, Zhaoqing Tang, Zhan Yu, Qing Wang, Zhong Li, Qicheng Lu, Yugang Wu

Pages: 1299-1305
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Article

Association of matrix metalloproteinase‑9 and decorin expression with the infiltration of cervical cancer

Tomohito Tanaka, Yoshito Terai, Masahide Ohmichi

Pages: 1306-1312
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Case Report

Conjunctival lymphomas in Japanese monozygotic twins: A case report

Naoya Ishibashi, Satoshi Sugaya, Hiromichi Takahashi, Haruna Nishimaki, Yoko Nakanishi, Yoshiaki Chinen, Toshiya Maebayashi

Pages: 1313-1319
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Article

Prospective analysis of the association between skeletal‑related events and quality of life in patients with advanced lung cancer (CSP‑HOR13)

Hiroshi Kunikane, Isao Yokota, Nobuyuki Katakami, Koji Takeda, Koichi Takayama, Toshiyuki Sawa, Hiroshi Saito, Masao Harada, Soichiro Yokota, Kiyoshi Ando, Yuko Saito, Yasuo Ohashi, Kenji Eguchi

Pages: 1320-1326
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Article

miR‑106a contributes to prostate carcinoma progression through PTEN

Ji Lu, Xupeng Mu, Qinan Yin, Kebang Hu

Pages: 1327-1332
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Article

PTEN inhibits non‑small cell lung cancer cell growth by promoting G0/G1 arrest and cell apoptosis

Libao Liu, Lei Huang, Jinyuan He, Songwang Cai, Yimin Weng, Shaohong Huang, Shaohong Ma

Pages: 1333-1340
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Article

Outcomes of stage II‑IV upper‑tract urothelial carcinoma and adjuvant chemotherapy for locally advanced cancer

Yi‑Huei Chang, Po‑Jen Hsiao, Guang‑Heng Chen, Ching‑Chan Lin, Chao‑Hsiang Chang, Hsi‑Chin Wu, Chi‑Ping Huang, Chi‑Rei Yang, Su‑Peng Yeh

Pages: 1341-1348
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Article

Circulating immune biomarkers as predictors of the response to pembrolizumab and weekly low dose carboplatin and paclitaxel in NSCLC and poor PS: An interim analysis

Marcelo Bonomi, Tamjeed Ahmed, Safoa Addo, Mitra Kooshki, Dario Palmieri, Beverly J. Levine, Jimmy Ruiz, Stefan Grant, William J. Petty, Pierre L. Triozzi

Pages: 1349-1356
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Article

Variation of nicotinic subtype α7 and muscarinic subtype M3 acetylcholine receptor expression in three main types of leukemia

Tawit Suriyo, Sadudee Chotirat, Chirayu U. Auewarakul, Karnjana Chaiyot, Orathai Promsuwicha, Jutamaad Satayavivad

Pages: 1357-1362
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Article

miR‑142‑5p suppresses proliferation and promotes apoptosis of human osteosarcoma cell line, HOS, by targeting PLA2G16 through the ERK1/2 signaling pathway

Deliang Cheng, Jiageng Li, Lijun Zhang, Leiming Hu

Pages: 1363-1371
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Article

Triptolide suppresses the proliferation and induces the apoptosis of nasopharyngeal carcinoma cells via the PI3K/Akt pathway

Mi Wang, Bo Chen , Liang Chai

Pages: 1372-1378
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Article

MicroRNA expression in pediatric intracranial ependymomas and their potential value for tumor grading

Šimon Cipro, Marie Belhajová, Tomáš Eckschlager, Josef Zámečník

Pages: 1379-1383
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Article

Treatment package time predicts cancer‑specific survival and distant metastasis in laryngeal cancer

Hidenori Suzuki, Hoshino Terada, Nobuhiro Hanai, Daisuke Nishikawa, Yusuke Koide, Shintaro Beppu, Takeshi Kodaira, Hiroyuki Tachibana, Yutaro Koide, Hiroshi Tanaka, Yasuhisa Hasegawa

Pages: 1384-1390
Published online on: 05 November 2018

July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing

Article Number: 321
Published online on: 02 June 2026

Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu

Article Number: 320
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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

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Article Number: 319
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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He

Article Number: 318
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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang

Article Number: 317
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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang

Article Number: 316
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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji

Article Number: 315
Published online on: 26 May 2026

Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

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Article Number: 314
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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma

Article Number: 313
Published online on: 25 May 2026

Article Open Access

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Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli

Article Number: 312
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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu

Article Number: 311
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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang

Article Number: 310
Published online on: 21 May 2026

Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu

Article Number: 309
Published online on: 21 May 2026

Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang

Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose

Article Number: 307
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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi

Article Number: 306
Published online on: 20 May 2026

Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang

Article Number: 305
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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li

Article Number: 304
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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong

Article Number: 303
Published online on: 19 May 2026

Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu

Article Number: 302
Published online on: 19 May 2026

Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao

Article Number: 301
Published online on: 19 May 2026

Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun

Article Number: 300
Published online on: 19 May 2026

Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu

Article Number: 299
Published online on: 18 May 2026

Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen

Article Number: 298
Published online on: 18 May 2026

Review Open Access

Ubiquitination and N⁶‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu

Article Number: 297
Published online on: 18 May 2026

Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G₀/G₁ cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao

Article Number: 296
Published online on: 15 May 2026

Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang

Article Number: 295
Published online on: 14 May 2026

Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong

Article Number: 294
Published online on: 14 May 2026

Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu

Article Number: 293
Published online on: 13 May 2026

Article Open Access

Gastrointestinal cancer with indeterminate ¹⁸F‑FDG PET/CT findings: Diagnostic efficacy analysis of ⁶⁸Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang

Article Number: 292
Published online on: 13 May 2026

Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu

Article Number: 291
Published online on: 13 May 2026

Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang

Article Number: 290
Published online on: 11 May 2026

Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang

Article Number: 289
Published online on: 11 May 2026

Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao

Article Number: 288
Published online on: 08 May 2026

Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun

Article Number: 287
Published online on: 08 May 2026

Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang

Article Number: 286
Published online on: 07 May 2026

Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong

Article Number: 285
Published online on: 07 May 2026

Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang

Article Number: 284
Published online on: 06 May 2026

Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis

Article Number: 283
Published online on: 06 May 2026

Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu

Article Number: 282
Published online on: 06 May 2026

Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song

Article Number: 281
Published online on: 05 May 2026

Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding

Article Number: 280
Published online on: 05 May 2026

Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova

Article Number: 279
Published online on: 04 May 2026

Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu

Article Number: 278
Published online on: 04 May 2026

Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang

Article Number: 277
Published online on: 29 April 2026

Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan

Article Number: 276
Published online on: 28 April 2026

Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi

Article Number: 275
Published online on: 28 April 2026

Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura

Article Number: 274
Published online on: 28 April 2026

Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen

Article Number: 273
Published online on: 28 April 2026

Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li

Article Number: 272
Published online on: 28 April 2026

Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar

Article Number: 271
Published online on: 28 April 2026

Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang

Article Number: 270
Published online on: 28 April 2026

Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei

Article Number: 269
Published online on: 28 April 2026

August-2026 Volume 32 Issue 2

Full Size Image

Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang

Article Number: 347
Published online on: 12 June 2026

Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie

Article Number: 346
Published online on: 12 June 2026

Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu

Article Number: 345
Published online on: 12 June 2026

Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang

Article Number: 344
Published online on: 11 June 2026

Correction Open Access

[Corrigendum] Engineered AXL^‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng

Article Number: 343
Published online on: 11 June 2026

Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang

Article Number: 342
Published online on: 11 June 2026

Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang

Article Number: 341
Published online on: 11 June 2026

Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu

Article Number: 340
Published online on: 11 June 2026

Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang

Article Number: 339
Published online on: 11 June 2026

Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu

Article Number: 338
Published online on: 11 June 2026

Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee

Article Number: 337
Published online on: 11 June 2026

Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias

Article Number: 336
Published online on: 11 June 2026

Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding

Article Number: 335
Published online on: 11 June 2026

Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias

Article Number: 334
Published online on: 11 June 2026

Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner

Article Number: 333
Published online on: 10 June 2026

Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li

Article Number: 332
Published online on: 08 June 2026

Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu

Article Number: 331
Published online on: 08 June 2026

Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng

Article Number: 330
Published online on: 05 June 2026

Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long

Article Number: 329
Published online on: 05 June 2026

Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao

Article Number: 328
Published online on: 05 June 2026

Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao

Article Number: 327
Published online on: 05 June 2026

Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang

Article Number: 326
Published online on: 03 June 2026

Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim

Article Number: 325
Published online on: 03 June 2026

Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera

Article Number: 323
Published online on: 03 June 2026

Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song

Article Number: 322
Published online on: 03 June 2026

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Medicine International

Patient‑derived xenograft mouse models: A high fidelity tool for individualized medicine (Review)

Cong Xu, Xuelu Li, Pixu Liu, Man Li, Fuwen Luo Pages: 3-10 Published online on: 16 October 2018

Pages: 3-10 Published online on: 16 October 2018

Clinical significance of exosomal miRNAs and proteins in three human cancers with high mortality in China (Review)

Li‑Man Li, Huan Liu, Xing‑Hui Liu, Hong‑Bin Hu, Song‑Mei Liu Pages: 11-22 Published online on: 29 October 2018

Pages: 11-22 Published online on: 29 October 2018

Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and cell migration/invasion (Review)

Ganiou Assani, Yunfeng Zhou Pages: 23-30 Published online on: 29 October 2018

Pages: 23-30 Published online on: 29 October 2018

Novel role of microRNA‑126 in digestive system cancers: From bench to bedside (Review)

Mingli Hu, Shengwei Xiong, Qiaofeng Chen, Shixuan Zhu, Xiaodong Zhou Pages: 31-41 Published online on: 29 October 2018

Pages: 31-41 Published online on: 29 October 2018

Effects of different doses of X‑ray irradiation on cell apoptosis, cell cycle, DNA damage repair and glycolysis in HeLa cells

Hong Zhao, Yafei Zhuang, Ruibin Li, Yinyin Liu, Zijie Mei, Zhongshi He, Fuxiang Zhou, Yunfeng Zhou Pages: 42-54 Published online on: 11 October 2018

Pages: 42-54 Published online on: 11 October 2018

MicroRNA 214 inhibits adipocyte enhancer‑binding protein 1 activity and increases the sensitivity of chemotherapy in colorectal cancer

Shouchao Li, Chengren Li, Zhiming Fang Pages: 55-62 Published online on: 26 October 2018

Pages: 55-62 Published online on: 26 October 2018

Expression pattern and level of ING5 protein in normal and cancer tissues

Xue‑Feng Yang, Dao‑Fu Shen, Shuang Zhao, Tian‑Ren Ren, Yang Gao, Shuai Shi, Ji‑Cheng Wu, Hong‑Zhi Sun, Hua‑Chuan Zheng Pages: 63-68 Published online on: 16 October 2018

Pages: 63-68 Published online on: 16 October 2018

A clinical study on the expression of PTEN in renal cell carcinoma in children

Hong Lu, Yuxia Tan, Liping Chen Pages: 69-72 Published online on: 12 October 2018

Pages: 69-72 Published online on: 12 October 2018

MiR‑506 inhibits cell proliferation, invasion, migration and epithelial‑to‑mesenchymal transition through targeting RWDD4 in human bladder cancer

Yi Hou Pages: 73-78 Published online on: 18 October 2018

Pages: 73-78 Published online on: 18 October 2018

Overexpression of Ulk2 inhibits proliferation and enhances chemosensitivity to cisplatin in non‑small cell lung cancer

Hong Cheng, Ze‑Tian Yang, Yu‑Quan Bai, Yan‑Fei Cai, Jin‑Ping Zhao Pages: 79-86 Published online on: 22 October 2018

Pages: 79-86 Published online on: 22 October 2018

miR‑125a is upregulated in cancer stem‑like cells derived from TW01 and is responsible for maintaining stemness by inhibiting p53

Jianjun Chen, Hui Ouyang, Xuemei An, Shixi Liu Pages: 87-94 Published online on: 16 October 2018

Pages: 87-94 Published online on: 16 October 2018

Significance of TERT and ATRX mutations in glioma

Jiayu Liu, Xuebin Zhang, Xiaoling Yan, Mei Sun, Yueshan Fan, Ying Huang Pages: 95-102 Published online on: 29 October 2018

Pages: 95-102 Published online on: 29 October 2018

Downregulation of long noncoding RNA FENDRR predicts poor prognosis in renal cell carcinoma

Wang He, Guangzheng Zhong, Pei Wang, Chun Jiang, Ning Jiang, Jian Huang Pages: 103-112 Published online on: 26 October 2018

Pages: 103-112 Published online on: 26 October 2018

Basic transcription factor 3 expression silencing attenuates colon cancer cell proliferation and migration in vitro

Xu Li, Jinke Sui, Junjie Xing, Fuao Cao, Hao Wang, Chuangang Fu, Hantao Wang Pages: 113-118 Published online on: 24 October 2018

Pages: 113-118 Published online on: 24 October 2018

Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi

Mengge Li, Yalin Zhao, Xiaoli Liu, Zhibo Dang, Xinhui Wang, Yuyong Jiang, Zhiyun Yang Pages: 119-126 Published online on: 17 October 2018

Pages: 119-126 Published online on: 17 October 2018

Apoptosis of mouse myeloma cells induced by curcumin via the Notch3‑p53 signaling axis

Ying Zhang, Xin‑Yu Lin, Jiao‑Hui Zhang, Zheng‑Lu Xie, Hui Deng, Yi‑Fang Huang, Xiao‑Hong Huang Pages: 127-134 Published online on: 17 October 2018

Pages: 127-134 Published online on: 17 October 2018

Downregulation of LPXN expression by siRNA decreases the malignant proliferation and transmembrane invasion of SHI‑1 cells

Guo‑Hua Zhu, Hai‑Ping Dai, Qun Shen, Qi Zhang Pages: 135-140 Published online on: 22 October 2018

Pages: 135-140 Published online on: 22 October 2018

High expression of density‑regulated re‑initiation and release factor drives tumourigenesis and affects clinical outcome

Dazhi Wang, Lanying Wang, Chunling Ren, Pei Zhang, Mengmeng Wang, Shuyu Zhang Pages: 141-148 Published online on: 25 October 2018

Pages: 141-148 Published online on: 25 October 2018

18F‑FDG‑PET/CT‑guided intensity‑modulated radiotherapy for 42 FIGO III/IV ovarian cancer: A retrospective study

Ya‑Zheng Dang, Xin Li, Yu‑Xin Ma, Xiao‑Long Li, Ting Yang, Wan‑Ling Lu, Shi‑Gao Huang Pages: 149-158 Published online on: 19 October 2018

Pages: 149-158 Published online on: 19 October 2018

Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer

Shengbo Tang, Xihong Yuan, Jintian Song, Yigui Chen, Xiaojie Tan, Qiyun Li Pages: 159-164 Published online on: 12 October 2018

Pages: 159-164 Published online on: 12 October 2018

Prognostic value of inflammation‑based indexes for intrahepatic cholangiocarcinoma following curative resection

Yunhua Wu, Fenggang Ren, Yichao Chai, Zhao Xue, Cong Shen, Xufeng Zhang, Yi Lv, Liangshuo Hu Pages: 165-174 Published online on: 24 October 2018

Pages: 165-174 Published online on: 24 October 2018

Lentiviral vector‑mediated IL‑9 overexpression stimulates cell proliferation by targeting c‑myc and cyclin D1 in colitis‑associated cancer

Linglin Tian, Yuan Li, Ruqi Chang, Peng Zhang, Jian Zhang, Lijuan Huo Pages: 175-182 Published online on: 11 October 2018

Pages: 175-182 Published online on: 11 October 2018

Association of BRAF gene and TSHR with cervical lymph node metastasis of papillary thyroid microcarcinoma

Cong Xu, Xuelu Li, Pixu Liu, Man Li, Fuwen Luo

Pages: 3-10
Published online on: 16 October 2018

Pages: 3-10
Published online on: 16 October 2018

Li‑Man Li, Huan Liu, Xing‑Hui Liu, Hong‑Bin Hu, Song‑Mei Liu

Pages: 11-22
Published online on: 29 October 2018

Pages: 11-22
Published online on: 29 October 2018

Ganiou Assani, Yunfeng Zhou

Pages: 23-30
Published online on: 29 October 2018

Pages: 23-30
Published online on: 29 October 2018

Mingli Hu, Shengwei Xiong, Qiaofeng Chen, Shixuan Zhu, Xiaodong Zhou

Pages: 31-41
Published online on: 29 October 2018

Pages: 31-41
Published online on: 29 October 2018

Hong Zhao, Yafei Zhuang, Ruibin Li, Yinyin Liu, Zijie Mei, Zhongshi He, Fuxiang Zhou, Yunfeng Zhou

Pages: 42-54
Published online on: 11 October 2018

Pages: 42-54
Published online on: 11 October 2018

Shouchao Li, Chengren Li, Zhiming Fang

Pages: 55-62
Published online on: 26 October 2018

Pages: 55-62
Published online on: 26 October 2018

Xue‑Feng Yang, Dao‑Fu Shen, Shuang Zhao, Tian‑Ren Ren, Yang Gao, Shuai Shi, Ji‑Cheng Wu, Hong‑Zhi Sun, Hua‑Chuan Zheng

Pages: 63-68
Published online on: 16 October 2018

Pages: 63-68
Published online on: 16 October 2018

Hong Lu, Yuxia Tan, Liping Chen

Pages: 69-72
Published online on: 12 October 2018

Pages: 69-72
Published online on: 12 October 2018

Yi Hou

Pages: 73-78
Published online on: 18 October 2018

Pages: 73-78
Published online on: 18 October 2018

Hong Cheng, Ze‑Tian Yang, Yu‑Quan Bai, Yan‑Fei Cai, Jin‑Ping Zhao

Pages: 79-86
Published online on: 22 October 2018

Pages: 79-86
Published online on: 22 October 2018

Jianjun Chen, Hui Ouyang, Xuemei An, Shixi Liu

Pages: 87-94
Published online on: 16 October 2018

Pages: 87-94
Published online on: 16 October 2018

Jiayu Liu, Xuebin Zhang, Xiaoling Yan, Mei Sun, Yueshan Fan, Ying Huang

Pages: 95-102
Published online on: 29 October 2018

Pages: 95-102
Published online on: 29 October 2018

Wang He, Guangzheng Zhong, Pei Wang, Chun Jiang, Ning Jiang, Jian Huang

Pages: 103-112
Published online on: 26 October 2018

Pages: 103-112
Published online on: 26 October 2018

Xu Li, Jinke Sui, Junjie Xing, Fuao Cao, Hao Wang, Chuangang Fu, Hantao Wang

Pages: 113-118
Published online on: 24 October 2018

Pages: 113-118
Published online on: 24 October 2018

Mengge Li, Yalin Zhao, Xiaoli Liu, Zhibo Dang, Xinhui Wang, Yuyong Jiang, Zhiyun Yang

Pages: 119-126
Published online on: 17 October 2018

Pages: 119-126
Published online on: 17 October 2018

Ying Zhang, Xin‑Yu Lin, Jiao‑Hui Zhang, Zheng‑Lu Xie, Hui Deng, Yi‑Fang Huang, Xiao‑Hong Huang

Pages: 127-134
Published online on: 17 October 2018

Pages: 127-134
Published online on: 17 October 2018

Guo‑Hua Zhu, Hai‑Ping Dai, Qun Shen, Qi Zhang

Pages: 135-140
Published online on: 22 October 2018

Pages: 135-140
Published online on: 22 October 2018

Dazhi Wang, Lanying Wang, Chunling Ren, Pei Zhang, Mengmeng Wang, Shuyu Zhang

Pages: 141-148
Published online on: 25 October 2018

Pages: 141-148
Published online on: 25 October 2018

Ya‑Zheng Dang, Xin Li, Yu‑Xin Ma, Xiao‑Long Li, Ting Yang, Wan‑Ling Lu, Shi‑Gao Huang

Pages: 149-158
Published online on: 19 October 2018

Pages: 149-158
Published online on: 19 October 2018

Shengbo Tang, Xihong Yuan, Jintian Song, Yigui Chen, Xiaojie Tan, Qiyun Li

Pages: 159-164
Published online on: 12 October 2018

Pages: 159-164
Published online on: 12 October 2018

Yunhua Wu, Fenggang Ren, Yichao Chai, Zhao Xue, Cong Shen, Xufeng Zhang, Yi Lv, Liangshuo Hu

Pages: 165-174
Published online on: 24 October 2018

Pages: 165-174
Published online on: 24 October 2018

Linglin Tian, Yuan Li, Ruqi Chang, Peng Zhang, Jian Zhang, Lijuan Huo

Pages: 175-182
Published online on: 11 October 2018

Pages: 175-182
Published online on: 11 October 2018

Changxin Zhou, Jinbo Li, Yu Wang, Shoukun Xue, Yang Zhang

Pages: 183-194
Published online on: 12 October 2018

Pages: 183-194
Published online on: 12 October 2018

Guomei Ye, Shifeng Kan, Jianfeng Chen, Xin Lu

Pages: 195-200
Published online on: 19 October 2018

Pages: 195-200
Published online on: 19 October 2018

Xiaobin Wang, Huihan Wang, Yongsheng Song

Pages: 201-208
Published online on: 24 October 2018

Pages: 201-208
Published online on: 24 October 2018

Qiaohong Pan, Jianwu Ji

Pages: 209-214
Published online on: 17 October 2018

Pages: 209-214
Published online on: 17 October 2018

Zichuan Liu

Pages: 215-220
Published online on: 12 October 2018

Pages: 215-220
Published online on: 12 October 2018

Shuaiyu Zheng, Xiaojin Zhang, Xian Wang, Jiyuan Li

Pages: 221-229
Published online on: 23 October 2018

Pages: 221-229
Published online on: 23 October 2018

Xiao‑Zhu Zhong, Yun Deng, Gang Chen, Hong Yang

Pages: 230-246
Published online on: 26 October 2018

Pages: 230-246
Published online on: 26 October 2018

Chen Su, Hanwei Li, Zheng Peng, Dong Ke, Hanjiang Fu, Xiaofei Zheng

Pages: 247-255
Published online on: 23 October 2018

Pages: 247-255
Published online on: 23 October 2018

Wei Wang, Huiliang Shen, Guanglei Cao, Jiang Huang

Pages: 256-262
Published online on: 18 October 2018

Pages: 256-262
Published online on: 18 October 2018

Luigi Valdatta, Gianpaolo Perletti, Francesca Maggiulli, Federico Tamborini, Igor Pellegatta, Mario Cherubino

Pages: 263-269
Published online on: 11 October 2018

Pages: 263-269
Published online on: 11 October 2018

Anna Höink, Thorsten Persigehl, Robert Kwiecien, Martin Balthasar, Rolf Mesters, Wolfgang Berdel, Walter Heindel, Christoph Bremer, Christian Schwöppe

Pages: 270-280
Published online on: 29 October 2018

Pages: 270-280
Published online on: 29 October 2018

Jianguo Wei, Jianfeng Yang, Wenqing Liang, Chunwei Xu, Yuanyuan Wen

Pages: 281-287
Published online on: 23 October 2018

Pages: 281-287
Published online on: 23 October 2018

Xiang Gao, Zhenping Liu, Meifeng Zhong, Kunhe Wu, Yuzhao Zhang, Hongmei Wang, Tao Zeng

Pages: 288-293
Published online on: 18 October 2018

Pages: 288-293
Published online on: 18 October 2018

Yi Sang, Ruhua Zhang, Longhua Sun, Kaddie Kwok Chen, Si‑Wei Li, Longxin Xiong, Yongjian Peng, Lei Zeng, Guofu Huang

Pages: 294-302
Published online on: 16 October 2018

Pages: 294-302
Published online on: 16 October 2018

Changshuang Fu, Jinyu Li, Adila Aipire, Lijie Xia, Yi Yang, Qiuyan Chen, Jie Lv, Xinhui Wang, Jinyao Li

Pages: 303-313
Published online on: 29 October 2018

Pages: 303-313
Published online on: 29 October 2018

Zhangwei Hu, Lei Wang, Yong Han, Fen Li, Anyuan Zheng, Yong Xu, Fei Wang, Bokui Xiao, Chen Chen, Zezhang Tao

Pages: 314-322
Published online on: 30 October 2018

Pages: 314-322
Published online on: 30 October 2018

Dian‑Xing Liu, Peng‑Peng Li, Jia‑Pei Guo, Lei‑Lei Li, Bin Guo, Hong‑Bin Jiao, Jing‑Hua Wu, Jun‑Mao Chen

Pages: 323-331
Published online on: 16 October 2018

Pages: 323-331
Published online on: 16 October 2018

Wenbo Niu, Guiying Wang, Jun Feng, Zheng Li, Chenhui Li, Baoen Shan

Pages: 332-338
Published online on: 23 October 2018

Pages: 332-338
Published online on: 23 October 2018