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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January-2019 Volume 17 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Patient‑derived xenograft mouse models: A high fidelity tool for individualized medicine (Review)

Cong Xu, Xuelu Li, Pixu Liu, Man Li, Fuwen Luo
Pages: 3-10
Published online on: 16 October 2018

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Review Open Access

Clinical significance of exosomal miRNAs and proteins in three human cancers with high mortality in China (Review)

Li‑Man Li, Huan Liu, Xing‑Hui Liu, Hong‑Bin Hu, Song‑Mei Liu
Pages: 11-22
Published online on: 29 October 2018

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Review Open Access

Effect of modulation of epithelial‑mesenchymal transition regulators Snail1 and Snail2 on cancer cell radiosensitivity by targeting of the cell cycle, cell apoptosis and cell migration/invasion (Review)

Ganiou Assani, Yunfeng Zhou
Pages: 23-30
Published online on: 29 October 2018

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Review Open Access

Novel role of microRNA‑126 in digestive system cancers: From bench to bedside (Review)

Mingli Hu, Shengwei Xiong, Qiaofeng Chen, Shixuan Zhu, Xiaodong Zhou
Pages: 31-41
Published online on: 29 October 2018

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Article Open Access

Effects of different doses of X‑ray irradiation on cell apoptosis, cell cycle, DNA damage repair and glycolysis in HeLa cells

Hong Zhao, Yafei Zhuang, Ruibin Li, Yinyin Liu, Zijie Mei, Zhongshi He, Fuxiang Zhou, Yunfeng Zhou
Pages: 42-54
Published online on: 11 October 2018

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Article Open Access

MicroRNA 214 inhibits adipocyte enhancer‑binding protein 1 activity and increases the sensitivity of chemotherapy in colorectal cancer

Shouchao Li, Chengren Li, Zhiming Fang
Pages: 55-62
Published online on: 26 October 2018

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Article Open Access

Expression pattern and level of ING5 protein in normal and cancer tissues

Xue‑Feng Yang, Dao‑Fu Shen, Shuang Zhao, Tian‑Ren Ren, Yang Gao, Shuai Shi, Ji‑Cheng Wu, Hong‑Zhi Sun, Hua‑Chuan Zheng
Pages: 63-68
Published online on: 16 October 2018

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Article Open Access

A clinical study on the expression of PTEN in renal cell carcinoma in children

Hong Lu, Yuxia Tan, Liping Chen
Pages: 69-72
Published online on: 12 October 2018

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Article

MiR‑506 inhibits cell proliferation, invasion, migration and epithelial‑to‑mesenchymal transition through targeting RWDD4 in human bladder cancer

Yi Hou
Pages: 73-78
Published online on: 18 October 2018

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Article Open Access

Overexpression of Ulk2 inhibits proliferation and enhances chemosensitivity to cisplatin in non‑small cell lung cancer

Hong Cheng, Ze‑Tian Yang, Yu‑Quan Bai, Yan‑Fei Cai, Jin‑Ping Zhao
Pages: 79-86
Published online on: 22 October 2018

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Article

miR‑125a is upregulated in cancer stem‑like cells derived from TW01 and is responsible for maintaining stemness by inhibiting p53

Jianjun Chen, Hui Ouyang, Xuemei An, Shixi Liu
Pages: 87-94
Published online on: 16 October 2018

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Article Open Access

Significance of TERT and ATRX mutations in glioma

Jiayu Liu, Xuebin Zhang, Xiaoling Yan, Mei Sun, Yueshan Fan, Ying Huang
Pages: 95-102
Published online on: 29 October 2018

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Article Open Access

Downregulation of long noncoding RNA FENDRR predicts poor prognosis in renal cell carcinoma

Wang He, Guangzheng Zhong, Pei Wang, Chun Jiang, Ning Jiang, Jian Huang
Pages: 103-112
Published online on: 26 October 2018

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Article Open Access

Basic transcription factor 3 expression silencing attenuates colon cancer cell proliferation and migration in vitro

Xu Li, Jinke Sui, Junjie Xing, Fuao Cao, Hao Wang, Chuangang Fu, Hantao Wang
Pages: 113-118
Published online on: 24 October 2018

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Article

Association and interaction between model for end‑stage liver disease score and minimally invasive treatment with regard to mortality of patients with hepatitis B virus‑associated hepatocellular carcinoma and portal vein tumor thrombi

Mengge Li, Yalin Zhao, Xiaoli Liu, Zhibo Dang, Xinhui Wang, Yuyong Jiang, Zhiyun Yang
Pages: 119-126
Published online on: 17 October 2018

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Article Open Access

Apoptosis of mouse myeloma cells induced by curcumin via the Notch3‑p53 signaling axis

Ying Zhang, Xin‑Yu Lin, Jiao‑Hui Zhang, Zheng‑Lu Xie, Hui Deng, Yi‑Fang Huang, Xiao‑Hong Huang
Pages: 127-134
Published online on: 17 October 2018

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Article Open Access

Downregulation of LPXN expression by siRNA decreases the malignant proliferation and transmembrane invasion of SHI‑1 cells

Guo‑Hua Zhu, Hai‑Ping Dai, Qun Shen, Qi Zhang
Pages: 135-140
Published online on: 22 October 2018

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Article Open Access

High expression of density‑regulated re‑initiation and release factor drives tumourigenesis and affects clinical outcome

Dazhi Wang, Lanying Wang, Chunling Ren, Pei Zhang, Mengmeng Wang, Shuyu Zhang
Pages: 141-148
Published online on: 25 October 2018

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Article Open Access

18F‑FDG‑PET/CT‑guided intensity‑modulated radiotherapy for 42 FIGO III/IV ovarian cancer: A retrospective study

Ya‑Zheng Dang, Xin Li, Yu‑Xin Ma, Xiao‑Long Li, Ting Yang, Wan‑Ling Lu, Shi‑Gao Huang
Pages: 149-158
Published online on: 19 October 2018

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Article Open Access

Association analyses of the JAK/STAT signaling pathway with the progression and prognosis of colon cancer

Shengbo Tang, Xihong Yuan, Jintian Song, Yigui Chen, Xiaojie Tan, Qiyun Li
Pages: 159-164
Published online on: 12 October 2018

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Article Open Access

Prognostic value of inflammation‑based indexes for intrahepatic cholangiocarcinoma following curative resection

Yunhua Wu, Fenggang Ren, Yichao Chai, Zhao Xue, Cong Shen, Xufeng Zhang, Yi Lv, Liangshuo Hu
Pages: 165-174
Published online on: 24 October 2018

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Article Open Access

Lentiviral vector‑mediated IL‑9 overexpression stimulates cell proliferation by targeting c‑myc and cyclin D1 in colitis‑associated cancer

Linglin Tian, Yuan Li, Ruqi Chang, Peng Zhang, Jian Zhang, Lijuan Huo
Pages: 175-182
Published online on: 11 October 2018

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Article Open Access

Association of BRAF gene and TSHR with cervical lymph node metastasis of papillary thyroid microcarcinoma

Changxin Zhou, Jinbo Li, Yu Wang, Shoukun Xue, Yang Zhang
Pages: 183-194
Published online on: 12 October 2018

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Article Open Access

Puerarin in inducing apoptosis of bladder cancer cells through inhibiting SIRT1/p53 pathway

Guomei Ye, Shifeng Kan, Jianfeng Chen, Xin Lu
Pages: 195-200
Published online on: 19 October 2018

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Article Open Access

Clinical efficacy and mechanism of Pralatrexate combined with Palbociclib Isethionate in treatment of bladder cancer patients

Xiaobin Wang, Huihan Wang, Yongsheng Song
Pages: 201-208
Published online on: 24 October 2018

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Article Open Access

Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer

Qiaohong Pan, Jianwu Ji
Pages: 209-214
Published online on: 17 October 2018

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Article Open Access

Clinical effects of high frequency hyperthermia-assisted irinotecan chemotherapy on patients with middle and advanced colorectal cancer and its safety assessment

Zichuan Liu
Pages: 215-220
Published online on: 12 October 2018

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Article Open Access

MIR31HG promotes cell proliferation and invasion by activating the Wnt/β‑catenin signaling pathway in non‑small cell lung cancer

Shuaiyu Zheng, Xiaojin Zhang, Xian Wang, Jiyuan Li
Pages: 221-229
Published online on: 23 October 2018

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Article Open Access

Investigation of the clinical significance and molecular mechanism of miR‑21‑5p in hepatocellular carcinoma: A systematic review based on 24 studies and bioinformatics investigation

Xiao‑Zhu Zhong, Yun Deng, Gang Chen, Hong Yang
Pages: 230-246
Published online on: 26 October 2018

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Article Open Access

Identification of plasma RGS18 and PPBP mRNAs as potential biomarkers for gastric cancer using transcriptome arrays

Chen Su, Hanwei Li, Zheng Peng, Dong Ke, Hanjiang Fu, Xiaofei Zheng
Pages: 247-255
Published online on: 23 October 2018

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Article Open Access

Long non‑coding RNA XIST predicts poor prognosis and promotes malignant phenotypes in osteosarcoma

Wei Wang, Huiliang Shen, Guanglei Cao, Jiang Huang
Pages: 256-262
Published online on: 18 October 2018

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Article Open Access

FRAIL scale as a predictor of complications and mortality in older patients undergoing reconstructive surgery for non‑melanoma skin cancer

Luigi Valdatta, Gianpaolo Perletti, Francesca Maggiulli, Federico Tamborini, Igor Pellegatta, Mario Cherubino
Pages: 263-269
Published online on: 11 October 2018

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Article Open Access

Gadofosveset‑enhanced MRI as simple surrogate parameter for real‑time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF‑NGR

Anna Höink, Thorsten Persigehl, Robert Kwiecien, Martin Balthasar, Rolf Mesters, Wolfgang Berdel, Walter Heindel, Christoph Bremer, Christian Schwöppe
Pages: 270-280
Published online on: 29 October 2018

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Case Report Open Access

Clinicopathological features of primary thyroid leiomyosarcoma without Epstein‑Barr virus infection: A case report

Jianguo Wei, Jianfeng Yang, Wenqing Liang, Chunwei Xu, Yuanyuan Wen
Pages: 281-287
Published online on: 23 October 2018

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Article Open Access

Knockdown of DNA/RNA‑binding protein KIN17 promotes apoptosis of triple‑negative breast cancer cells

Xiang Gao, Zhenping Liu, Meifeng Zhong, Kunhe Wu, Yuzhao Zhang, Hongmei Wang, Tao Zeng
Pages: 288-293
Published online on: 18 October 2018

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Article Open Access

MORF4L1 suppresses cell proliferation, migration and invasion by increasing p21 and E‑cadherin expression in nasopharyngeal carcinoma

Yi Sang, Ruhua Zhang, Longhua Sun, Kaddie Kwok Chen, Si‑Wei Li, Longxin Xiong, Yongjian Peng, Lei Zeng, Guofu Huang
Pages: 294-302
Published online on: 16 October 2018

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Article Open Access

Cistanche tubulosa phenylethanoid glycosides induce apoptosis in Eca‑109 cells via the mitochondria‑dependent pathway

Changshuang Fu, Jinyu Li, Adila Aipire, Lijie Xia, Yi Yang, Qiuyan Chen, Jie Lv, Xinhui Wang, Jinyao Li
Pages: 303-313
Published online on: 29 October 2018

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Article Open Access

Ferritin: A potential serum marker for lymph node metastasis in head and neck squamous cell carcinoma

Zhangwei Hu, Lei Wang, Yong Han, Fen Li, Anyuan Zheng, Yong Xu, Fei Wang, Bokui Xiao, Chen Chen, Zezhang Tao
Pages: 314-322
Published online on: 30 October 2018

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Article Open Access

Exosomes derived from HBV‑associated liver cancer promote chemoresistance by upregulating chaperone‑mediated autophagy

Dian‑Xing Liu, Peng‑Peng Li, Jia‑Pei Guo, Lei‑Lei Li, Bin Guo, Hong‑Bin Jiao, Jing‑Hua Wu, Jun‑Mao Chen
Pages: 323-331
Published online on: 16 October 2018

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Article Open Access

Correlation between microsatellite instability and RAS gene mutation and stage Ⅲ colorectal cancer

Wenbo Niu, Guiying Wang, Jun Feng, Zheng Li, Chenhui Li, Baoen Shan
Pages: 332-338
Published online on: 23 October 2018

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Article Open Access

Effects of complement and serum IgG on rituximab‑dependent natural killer cell‑mediated cytotoxicity against Raji cells

Yang Li, Ke Huang, Ling Liu, Yuhua Qu, Yan Huang, Yanfeng Wu, Jing Wei
Pages: 339-347
Published online on: 29 October 2018

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Article Open Access

Analysis of the inhibitory effects of miR‑124 and miR-152 on human epithelial ovarian cancer xenografts in a nude mouse model

Weiwei Liu, Lixia Zhang, Jing Wang, Xiaoli Wang, Hong Sun
Pages: 348-354
Published online on: 24 October 2018

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Article Open Access

Values of thoracic contrast‑enhanced computed tomography in detecting incidental pulmonary thromboembolism in patients with malignant tumors

Lijuan Dai, Gaofeng Shi, Yang Li, Bo Zhao
Pages: 355-359
Published online on: 15 October 2018

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Article Open Access

A hybrid technique for treating multilevel cervical myelopathy: Cervical artificial disc replacement combined with fusion

Yunrong Zhu, Jianfeng Fang, Guohua Xu, Xiaojian Ye, Yunqing Zhang
Pages: 360-364
Published online on: 12 October 2018

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Article Open Access

MicroRNA‑24‑3p regulates Hodgkin's lymphoma cell proliferation, migration and invasion by targeting DEDD

Jing Wang, Kai Yin, Xianping Lv, Qiankun Yang, Ming Shao, Xin Liu, Hui Sun
Pages: 365-371
Published online on: 19 October 2018

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Article Open Access

miR-149-5p inhibits cell proliferation and invasion through targeting GIT1 in medullary thyroid carcinoma

Xiaojuan Ye, Xiaofang Chen
Pages: 372-378
Published online on: 26 October 2018

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Article

Transgenic overexpression of human LY6K in mice suppresses mature T cell development in the thymus

Dasom Son, Hyun-Kyung Kong, Yesol Kim, Min-Ji Song, Hyong Pyo Kim, Han Woong Lee, Jong Hoon Park
Pages: 379-387
Published online on: 04 October 2018

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Article

circRNA of AR‑suppressed PABPC1 91 bp enhances the cytotoxicity of natural killer cells against hepatocellular carcinoma via upregulating UL16 binding protein 1

Yuanming Ma, Chunjun Zhang, Bo Zhang, Haibo Yu, Qingsong Yu
Pages: 388-397
Published online on: 22 October 2018

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Article

Increased serum levels of miR‑214 in patients with PCa with bone metastasis may serve as a potential biomarker by targeting PTEN

Yi Fang, Jun Qiu, Zong‑Bin Jiang, Sheng‑Rong Xu, Zeng‑Hua Zhou, Rui‑Lin He
Pages: 398-405
Published online on: 28 September 2018

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Article

miR‑30a regulates the proliferation and invasion of breast cancer cells by targeting Snail

Baoqiang Xiao, Xuejing Shi, Jianping Bai
Pages: 406-413
Published online on: 05 October 2018

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Article

Silencing of miR‑19a‑3p enhances osteosarcoma cells chemosensitivity by elevating the expression of tumor suppressor PTEN

Bo Zhang, Yuan Liu, Jiangnan Zhang
Pages: 414-421
Published online on: 17 October 2018

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Article

Su Yang Decoction induces human colon carcinoma cell apoptosis by activating caspases

Yazhong Ge, Qing Gao, Fengjiao Yan, Xiaona Zhang, Yurong Liu, Yi Zhou
Pages: 422-431
Published online on: 26 October 2018

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Article

Identification of prognostic genes in colorectal cancer through transcription profiling of multi‑stage carcinogenesis

Ning An, Chen Zhao, Zhuang Yu, Xue Yang
Pages: 432-441
Published online on: 29 October 2018

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Article

Cancer stem cell associated eight gene‑based signature predicts clinical outcomes of colorectal cancer

Chuanpeng Dong, Danni Cui, Gang Liu, Huilin Xu, Xueqing Peng, Juan Duan, Lei Liu
Pages: 442-449
Published online on: 01 October 2018

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Article

Effects of tanshinones mediated by forkhead box O3a transcription factor on the proliferation and apoptosis of lung cancer cells

Dongjie  Liu, Renbing  Yuan, Fang  Yang, Dehui  Zhang
Pages: 450-455
Published online on: 01 October 2018

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Article

Norcantharidin inhibits viability and induces cell cycle arrest and apoptosis in osteosarcoma

Yingchun Zhu, Yunfeng Mi, Zheyang Wang, Xuewen Jia, Zhanping Jin
Pages: 456-461
Published online on: 24 October 2018

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Case Report

Urothelial bladder carcinoma metastasizing to the eye: A systematic review and case report

Guido Giordano, Nunzio Olivieri, Mario Rosario D'Andrea, Tania Di Raimo, Erminia Manfrin, Andrea Remo, Massimo Pancione, Matteo Brunelli, Elena De Santis, Giulia Coppola, Aldo Scarpa, Luigi Coppola, Pietro Parcesepe
Pages: 462-467
Published online on: 15 October 2018

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Article

Identification of core genes and prediction of miRNAs associated with osteoporosis using a bioinformatics approach

Yi Chai, Feng Tan, Sumin Ye, Feixiang Liu, Qiaoling Fan
Pages: 468-481
Published online on: 26 September 2018

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Article

Forkhead box O1 as an indicator of prognosis is inactivated in urothelial carcinoma of the upper urinary tract

Hiroki Ide, Guiyang Jiang, Taichi Mizushima, Kazutoshi Fujita, Satoshi Inoue, Seiji Yamaguchi, Hiroaki Fushimi, Norio Nonomura, Hiroshi Miyamoto
Pages: 482-487
Published online on: 26 September 2018

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Case Report

ROS1‑rearranged high‑PD‑L1‑expressing lung adenocarcinoma manifesting as mediastinal tumor: A case report

Hiroyuki Ogawa, Yugo Tanaka, Motoko Tachihara, Keiichiro Uehara, Nahoko Shimizu, Takefumi Doi, Daisuke Hokka, Yoshimasa Maniwa
Pages: 488-491
Published online on: 25 October 2018

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Article

Identification of potential genes and pathways for response prediction of neoadjuvant chemoradiotherapy in patients with rectal cancer by systemic biological analysis

Qiliang Peng, Kaisu Lin, Yi Shen, Ping Zhou, Shaonan Fan, Yuntian Shen, Yaqun Zhu
Pages: 492-501
Published online on: 18 October 2018

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Article

Clinical significance of reduced GPRC5A expression in surgically resected non‑small cell lung cancer

Er Jin, Wenzhe Wang, Mengdie Fang, Wei Wang, Ruifei Xie, Hong Zhou, Jian Ye, Rujun Xu, Shenglin Ma
Pages: 502-507
Published online on: 02 October 2018

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Article

Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma

Lijian Gao, Hongda Zhao, Dongqing Zhang, Changkuo Zhou, Hui Wang, Chantao Ren, Yaxiao Liu, Yangyang Xia, Benkang Shi
Pages: 508-513
Published online on: 15 October 2018

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Case Report

Glomus tumor of the stomach treated by laparoscopic distal gastrectomy: A case report

Tsutomu Namikawa, Sachi Tsuda, Kazune Fujisawa, Jun Iwabu, Sunao Uemura, Shigehiro Tsujii, Hiromichi Maeda, Hiroyuki Kitagawa, Michiya Kobayashi, Kazuhiro Hanazaki
Pages: 514-517
Published online on: 25 October 2018

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Article

Use of ANGPTL2 mRNA levels in formalin‑fixed paraffin‑embedded tissues as a biomarker to diagnose gastric cancer and to evaluate the extent of vascular invasion

Takuma Yoshinaga, Hiroto Nishimata, Sadao Tanaka, Emiko Hori, Ayako Tomiyoshi, Erena Tokudome, Takayuki Takei, Masahiro Yoshida
Pages: 518-524
Published online on: 23 October 2018

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Article

Lentiviral RNA interference‑mediated downregulation of Forkhead box M1 expression suppresses growth of oral squamous cell carcinoma in vitro

Jing Qiu, Juan Zhao, Anjun Zuo, Lan Liu, Qiaoqiao Liu, Huazheng Pan, Xiao Yuan
Pages: 525-531
Published online on: 02 October 2018

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Article

Müllerian inhibiting substance/anti‑Müllerian hormone type II receptor protein and mRNA expression in the healthy and cancerous endometria

Su Mi Kim, Yun Oh Kim, Min Kyoung Lee, Youn Jee Chung, In Cheul Jeung, Mee Ran Kim, Jang Heub Kim
Pages: 532-538
Published online on: 10 October 2018

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Article

Characterizing the landscape of peritoneal exosomal microRNAs in patients with ovarian cancer by high‑throughput sequencing

Yuankun Li, Cuihua Liu, Yumei Liao, Wuliang Wang, Bin Hu, Xiaoqin Lu, Jinquan Cui
Pages: 539-547
Published online on: 09 October 2018

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Article

MicroRNA‑183 inhibits A375 human melanoma cell migration and invasion by targeting Ezrin and MMP‑9

Yusen Zhang, Guoqiang Wang
Pages: 548-554
Published online on: 22 October 2018

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Article

NANOGP8 expression regulates gastric cancer cell progression by transactivating DBC1 in gastric cancer MKN‑45 cells

Li Li, Ru Feng, Sujuan Fei, Jiang Cao, Qinqin Zhu, Guozhong Ji, Jianwei Zhou
Pages: 555-563
Published online on: 18 October 2018

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Article

Capn4 regulates migration and invasion of ovarian carcinoma cells via targeting osteopontin‑mediated PI3K/AKT signaling pathway

Yuanyuan Chen, Gang Wang, Yingmei Wang, Xiaoli Gao, Kan Wang, Jie Li, Fengxia Xue
Pages: 564-570
Published online on: 28 September 2018

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Article

miR‑218 suppresses the proliferation of osteosarcoma through downregulation of E2F2

Chengmin Xuan, Mingwei Jin, Yong Gao, Shumei Xu, Lei Wang, Yuan Wang, Rui Han, Qi An
Pages: 571-577
Published online on: 15 October 2018

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Article

Carcinosarcoma of the esophagus: A report of 6 cases associated with zinc finger E‑box‑binding homeobox 1 expression

Hiroki Harada, Kei Hosoda, Hiromitsu Moriya, Hiroaki Mieno, Akira Ema, Marie Washio, Mariko Kikuchi, Yoshimasa Kosaka, Masahiko Watanabe, Keishi Yamashita
Pages: 578-586
Published online on: 16 October 2018

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Article

An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma

Rei Suzuki, Tadayuki Takagi, Takuto Hikichi, Mitsuru Sugimoto, Naoki Konno, Hiroyuki Asama, Ko Watanabe, Jun Nakamura, Shigeru Marubashi, Hiromasa Ohira
Pages: 587-593
Published online on: 26 October 2018

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Article

Nedaplatin‑based chemotherapy regimens combined with concurrent radiotherapy as first‑line treatment for stage II‑III esophageal squamous cell carcinoma

Huiping Zhu, Xiaolin Ge, Yufeng Lu, Yun Zuo, Qin Qin, Xinchen Sun, Min Yang
Pages: 594-602
Published online on: 10 October 2018

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Article

Synergistic action of microwave‑induced mild hyperthermia and paclitaxel in inducing apoptosis in the human breast cancer cell line MCF‑7

Sina Liao, Xiaohua Hu, Zhihui Liu, Yan Lin, Rong Liang, Yumei Zhang, Qian Li, Yongqiang Li, Xiaoli Liao
Pages: 603-615
Published online on: 29 October 2018

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Article

Ki‑67 index value and progesterone receptor status can predict prognosis and suitable treatment in node‑negative breast cancer patients with estrogen receptor‑positive and HER2‑negative tumors

Nobuyuki Arima, Reiki Nishimura, Tomofumi Osako, Yasuhiro Okumura, Masahiro Nakano, Mamiko Fujisue, Yasuyuki Nishiyama, Yasuo Toyozumi
Pages: 616-622
Published online on: 29 October 2018

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Article

Genetic influence of cytokine polymorphisms on the clinical outcome of Japanese gastrointestinal cancer patients in palliative care

Asahi Hishida, Yoshinaga Okugawa, Yuhki Morimoto, Yumiko Shirai, Kyoko Okamoto, Sachiko Momokita, Aki Ogawa, Koji Tanaka, Ryutaro Nishikawa, Yuji Toiyama, Yasuhiro Inoue, Hiroyuki Sakurai, Hisashi Urata, Motoyoshi Tanaka, Donald C. McMillan, Chikao Miki
Pages: 623-629
Published online on: 24 October 2018

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Article

Rotundic acid induces Cas3‑MCF‑7 cell apoptosis through the p53 pathway

Min‑Lun Nan, Xue Wang, Hai‑Jun Li, De‑Hai Yu, Wen‑Yi Sun, Hong‑Mei Xu, Yu‑Fang He, Quan‑Cheng Zhao
Pages: 630-637
Published online on: 24 October 2018

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Article

Enhanced cytotoxicity of human hepatocellular carcinoma cells following pretreatment with sorafenib combined with trichostatin A

John Chun‑Hao Chen, Hui‑Yen Chuang, Yi‑Jen Liao, Fei‑Ting Hsu, Yen‑Chung Chen, Wei‑Hsun Wang, Jeng‑Jong Hwang
Pages: 638-645
Published online on: 16 October 2018

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Article

MicroRNA‑153 affects nasopharyngeal cancer cell viability by targeting TGF‑β2

Guangliang Guo, Ying Zhang, Limin Hu, Xue Bian
Pages: 646-651
Published online on: 12 October 2018

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Article

Upregulation of TMEFF2 is involved in the antiproliferative effects of vitamin C and tyrphostin AG490 on GES‑1 and AGS cells

Hongchao Han, Jie Xu, Weiwei Ji, Lisheng Wang, Aikun Wang
Pages: 652-659
Published online on: 25 October 2018

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Article

Trichostatin A induces p53‑dependent endoplasmic reticulum stress in human colon cancer cells

Limeng Dai, Gang He, Kun Zhang, Xingying Guan, Yan Wang, Bo Zhang
Pages: 660-667
Published online on: 30 October 2018

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Article

Association between circadian and chemotherapeutic cycle effects on plasma concentration of 5‑fluorouracil and the clinical outcome following definitive 5‑fluorouracil/cisplatin‑based chemoradiotherapy in patients with esophageal squamous cell carcinoma

Akiko Kuwahara, Shinji Kobuchi, Takao Tamura
Pages: 668-675
Published online on: 16 October 2018

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Article

Rhamnetin induces apoptosis in human breast cancer cells via the miR‑34a/Notch‑1 signaling pathway

Lan Lan, Yue Wang, Zhanyu Pan, Bin Wang, Zhensong Yue, Zhansheng Jiang, Ling Li, Cong Wang, Hongmei Tang
Pages: 676-682
Published online on: 15 October 2018

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Article

Evaluation of the cytotoxic effect of Ly2109761 on HeLa cells using the xCELLigence RTCA system

İdi̇l Çeti̇n, Mehmet R. Topçul
Pages: 683-687
Published online on: 09 October 2018

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Article

MicroRNA‑342‑3p functions as a tumor suppressor by targeting LIM and SH3 protein 1 in oral squamous cell carcinoma

Xiaoyan Song, Yong Jin, Mingyu Yan, Yonggang Zhang, Bing Chen
Pages: 688-696
Published online on: 29 October 2018

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Article

Resveratrol integrates metabolic and growth effects in PC3 prostate cancer cells‑involvement of prolyl hydroxylase and hypoxia inducible factor‑1

Joao Fonseca, Fereshteh Moradi, Lucas A. Maddalena, Bruna Ferreira‑Tollstadius, Shehab Selim, Jeffrey A. Stuart
Pages: 697-705
Published online on: 28 September 2018

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Article

miR‑34a inhibits esophageal squamous cell carcinoma progression via regulation of FOXM1

Haibo Zhou, Li Yang, Xinhua Xu, Mingqian Lu, Rong Guo, Daojun Li, Qiao Huang, Yang Liu, Glenn Deng, Yalin Xu
Pages: 706-712
Published online on: 17 October 2018

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Article

Anticancer activity and phytochemical composition of wild Gundelia tournefortii

Saleh Abu‑Lafi, Baraa Rayan, Sleman Kadan, Malek Abu‑Lafi, Anwar Rayan
Pages: 713-717
Published online on: 19 October 2018

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Correction Open Access

[Erratum] Prognostic value of heterogeneous ribonucleoprotein A1 expression and inflammatory indicators for patients with surgically resected hepatocellular carcinoma: Perspectives from a high occurrence area of hepatocellular carcinoma in China

Ruisheng Ke, Lizhi Lv, Jiayan Li, Xiaojin Zhang, Fang Yang, Kun Zhang, Yi Jiang
Pages: 718-718
Published online on: 15 October 2018

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[Retracted] Effect of galectin‑3 on vasculogenic mimicry in esophageal cancer cells

Jingxin Zhang, Guodong Deng, Lili Qiao, Hui Luo, Qiqi Liu, Ning Liang, Jian Xie, Jiandong Zhang
Pages: 719-719
Published online on: 30 October 2018

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Review

Sirtuin 1 and oral cancer (Review)

Shajedul Islam, Yoshihiro Abiko, Osamu Uehara, Itsuo Chiba
Pages: 729-738
Published online on: 16 November 2018

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Fibrinogen is associated with EGFR mutation status and lymphatic metastasis in non‑small cell lung cancer

Jian Guan, Nan Xiao, Chun Qiu, Qin Li, Min Chen, Yao Zhang, Yong Dai, Lu Li, Yue Zhang, Mi Yang, Long Chen, Lai Yu Liu
Pages: 739-746
Published online on: 01 November 2018

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Macrophages activate mesenchymal stem cells to acquire cancer‑associated fibroblast‑like features resulting in gastric epithelial cell lesions and malignant transformation in vitro

Qiang Zhang, Shuo Chai, Wei Wang, Chengcheng Wan, Feng Zhang, Yuyun Li, Fengchao Wang
Pages: 747-756
Published online on: 15 November 2018

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JS‑K enhances chemosensitivity of prostate cancer cells to Taxol via reactive oxygen species activation

Mingning Qiu, Sai Zhang, Longzhi Ke, Huancheng Tang, Xin Zeng, Jianjun Liu
Pages: 757-764
Published online on: 09 November 2018

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Knockdown of CHCHD2 inhibits migration and angiogenesis of human renal cell carcinoma: A potential molecular marker for treatment of RCC

Qian Cheng, Debao Qu, Zheng Lu, Longzhen Zhang
Pages: 765-772
Published online on: 12 November 2018

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AKR1B10 expression predicts response of gastric cancer to neoadjuvant chemotherapy

Syed Minhaj Uddin Ahmed, Zi Nong Jiang, Zhao Hong Zheng, Yulong Li, Xiu Jun Wang, Xiuwen Tang
Pages: 773-780
Published online on: 15 November 2018

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MicroRNA‑525 enhances chondrosarcoma malignancy by targeting F‑spondin 1 Retraction in /10.3892/ol.2024.14676

Bo Liu, Xiandong Song, Zhaowei Yan, Hao Yang, Yingchao Shi, Jintao Wu
Pages: 781-788
Published online on: 15 November 2018

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Expression and clinical significance of basic transcription factor 3 in nasopharyngeal carcinoma

Ping Chen, Qi Zhong, Zufei Li, Yang Zhang, Zhigang Huang
Pages: 789-796
Published online on: 14 November 2018

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Extracellular matrix differences in glioblastoma patients with different prognoses

József Virga, László Szivos, Tibor Hortobágyi, Mahan Kouhsari Chalsaraei, Gábor Zahuczky, László Steiner, Judit Tóth, Judit Reményi‑Puskár, László Bognár, Almos Klekner
Pages: 797-806
Published online on: 31 October 2018

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miR‑410 acts as an oncogene in colorectal cancer cells by targeting dickkopf‑related protein 1 via the Wnt/β‑catenin signaling pathway

Wei Wang, Ying He, Jing Rui, Mao‑Qi Xu
Pages: 807-814
Published online on: 15 November 2018

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Inhibition of colorectal cancer liver metastasis in BALB/c mice following intratumoral injection of oncolytic herpes simplex virus type 2 for the induction of specific antitumor immunity

Wen Zhang, Feifei Wang, Xiao Hu, Jing Liang, Binlei Liu, Qi Guan, Shangmei Liu
Pages: 815-822
Published online on: 16 November 2018

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Case Report Open Access

A case of intrahepatic cholangiocarcinoma that was difficult to diagnose prior to surgery: A case report

Ken Nagata, Takahiro Einama, Akifumi Kimura, Michinori Murayama, Hiroteru Takeo, Makoto Nishikawa, Mayumi Hoshikawa, Takuji Noro, Sho Ogata, Suefumi Aosasa, Yoshiki Kajiwara, Eiji Shinto, Yoshihisa Yaguchi, Shuichi Hiraki, Hironori Tsujimoto, Kazuo Hase, Hideki Ueno, Junji Yamamoto
Pages: 823-830
Published online on: 05 November 2018

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Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer

Takao Iemoto, Shin Nishiumi, Takashi Kobayashi, Seiji Fujigaki, Tetsuya Hamaguchi, Ken Kato, Hirokazu Shoji, Yasuhiro Matsumura, Kazufumi Honda, Masaru Yoshida
Pages: 831-842
Published online on: 19 November 2018

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miR‑205 targets runt‑related transcription factor 2 to inhibit human pancreatic cancer progression

Lu Zhuang, Jia Guo, Yao Yao, Zhaoshen Li
Pages: 843-848
Published online on: 12 November 2018

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Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Pages: 849-856
Published online on: 05 November 2018

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Diprophylline inhibits non‑small cell lung cancer A549 cell proliferation and migration, and promotes apoptosis, by downregulating PI3K signaling pathway

Hong‑Ying Zhao, Yun‑Hui Ren, Xiu‑Bao Ren, Yu Wang
Pages: 857-862
Published online on: 08 November 2018

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Esophageal cancer N staging study with endoscopic ultrasonography

Yueming Zhang, Shun He, Lizhou Dou, Yong Liu, Yan Ke, Xinying Yu, Zhu Wang, Guiqi Wang
Pages: 863-870
Published online on: 16 November 2018

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Effect of interventional embolotherapy on FHIT and p16 expression in hepatocellular carcinoma patients Retraction in /10.3892/ol.2025.15318

Wei Xu, Xiaogai Qi, Xia Wang, Jize Sun
Pages: 871-876
Published online on: 31 October 2018

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Effects of FHIT gene on proliferation and apoptosis of osteosarcoma cells

Zhengfeng Xu, Jiajun Wu, Pan Cai, Xiaoxiao Zhou, Cunguo Yi, Bin Wang
Pages: 877-882
Published online on: 14 November 2018

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miR-29 promotes osteosarcoma cell proliferation and migration by targeting PTEN

Qiuliang Liu, Peishuo Geng, Longyan Shi, Qi Wang, Pengliang Wang
Pages: 883-890
Published online on: 31 October 2018

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Effects of mir-128a on the invasion and proliferation of glioma U251 cells

Guozhang Hu, Wei Fang, Naijie Liu, Chang Li
Pages: 891-896
Published online on: 01 November 2018

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Identification of key pathways and genes in endometrial cancer using bioinformatics analyses

Yan Liu, Teng Hua, Shuqi Chi, Hongbo Wang
Pages: 897-906
Published online on: 05 November 2018

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Efficacy and safety of TE/TEC/intensive paclitaxel neoadjuvant chemotherapy for the treatment of breast cancer

Yang Liu, Zhaoguo Xu, Zhenyong Zhang, Guangfu Wen, Jiaxing Sun, Feng Han
Pages: 907-912
Published online on: 01 November 2018

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Enhancement of cancer invasion and growth via the C5a‑C5a receptor system: Implications for cancer promotion by autoimmune diseases and association with cervical cancer invasion

Masakazu Yoneda, Ryuji Imamura, Hidetoshi Nitta, Keisuke Taniguchi, Fumitaka Saito, Ken Kikuchi, Hidenao Ogi, Takuya Tanaka, Hidetaka Katabuchi, Hideki Nakayama, Takahisa Imamura
Pages: 913-920
Published online on: 16 November 2018

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Expression profile of CADM1 and CADM4 in triple negative breast cancer with primary systemic therapy

Yasuyuki Kanke, Motonobu Saito, Noriko Abe, Katsuharu Saito, Akiteru Goto, Tohru Ohtake, Yoshinori Murakami, Koji Kono
Pages: 921-926
Published online on: 19 November 2018

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Cytokeratin expression in epidermal stem cells in skin adnexal tumors

Xiaoqiu Zhou, Guoyong Li, Dongguan Wang, Xiyin Sun, Xingong Li
Pages: 927-932
Published online on: 08 November 2018

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Two postoperative chemotherapies for gastric cancer: FOLFOX4 vs. TPF

Honghu Xie, Qicheng Lu, Haitao Wang, Xianbo Zhu, Zhong Guan
Pages: 933-936
Published online on: 14 November 2018

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Sirtuin‑7 knockdown inhibits the growth of endometrial cancer cells by inducing apoptosis via the NF‑κB signaling pathway

Shiqin Mao, Jimin Ma, Hong Yu
Pages: 937-943
Published online on: 14 November 2018

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Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Pages: 944-950
Published online on: 31 October 2018

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SNHG20 serves as a predictor for prognosis and promotes cell growth in oral squamous cell carcinoma

Pengjie Gao, Rui Fan, Tao Ge
Pages: 951-957
Published online on: 15 November 2018

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Deubiquitinating enzyme 4 facilitates chemoresistance in glioblastoma by inhibiting P53 activity

Na Qin, Fengli Han, Li Li, Yingwei Ge, Wei Lin, Jiang Wang, Lin Wu, Gang Zhao, Yanchun Deng, Jian Zhang
Pages: 958-964
Published online on: 01 November 2018

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Ginsenoside Rg3 inhibits the migration and invasion of liver cancer cells by increasing the protein expression of ARHGAP9

Meng‑Yao Sun, Ya‑Nan Song, Miao Zhang, Chun‑Yan Zhang, Li‑Jun Zhang, Hong Zhang
Pages: 965-973
Published online on: 15 November 2018

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Ki‑67 is an independent prognostic marker for the recurrence and relapse of oral squamous cell carcinoma

Yue Jing, Qian Zhou, Huidong Zhu, Ye Zhang, Yuxian Song, Xiaoxin Zhang, Xiaofeng Huang, Yan Yang, Yanhong Ni, Qingang Hu
Pages: 974-980
Published online on: 31 October 2018

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Local suture ligation‑assisted percutaneous sclerotherapy for Kasabach‑Merritt phenomenon‑associated kaposiform haemangioendothelioma

Xiao Li, Ming‑Zhe Wen, Li‑Xin Su, Xi‑Tao Yang, Yi‑Feng Han, Xin‑Dong Fan
Pages: 981-989
Published online on: 02 November 2018

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miR‑1207‑5p regulates the sensitivity of triple‑negative breast cancer cells to Taxol treatment via the suppression of LZTS1 expression

Xiaoke Hou, Zhaofeng Niu, Leilei Liu, Qiang Guo, Haiyang Li, Xiaojun Yang, Xia Zhang
Pages: 990-998
Published online on: 12 November 2018

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Bone mesenchymal stromal cells exhibit functional inhibition but no chromosomal aberrations in chronic myelogenous leukemia

Jieqiong Xie, Jiadi Chen, Bin Wang, Xuchun He, Huifang Huang
Pages: 999-1007
Published online on: 09 November 2018

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Anti‑neoplastic effect of mangiferin on human ovarian adenocarcinoma OVCAR8 cells via the regulation of YAP

Wenjing He, Yaodong You, Suya Du, Tiantian Lei, Hailian Wang, Xiang Li, Xia He, Rongsheng Tong, Yi Wang
Pages: 1008-1018
Published online on: 15 November 2018

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Increased serum levels of Galectin‑9 in patients with chronic lymphocytic leukemia

Kamil Wdowiak, Enrique Gallego‑Colon, Tomasz Francuz, Paulina Czajka‑Francuz, Natalia Ruiz‑Agamez, Marcin Kubeczko, Iga Grochoła, Maciej T. Wybraniec, Jerzy Chudek, Jerzy Wojnar
Pages: 1019-1029
Published online on: 01 November 2018

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Association between NF-κB expression and drug resistance of liver cancer

Tao Liu, Rendong Wei, Yiting Zhang, Wen Chen, Haidong Liu
Pages: 1030-1034
Published online on: 30 October 2018

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Identification of hub genes and pathways in glioblastoma by bioinformatics analysis

Shoubo Yang, Kaidi Gao, Wenbin Li
Pages: 1035-1041
Published online on: 31 October 2018

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Ex situ hepatectomy and liver autotransplantation for a treating giant solitary fibrous tumor: A case report

Zhongquan Sun, Yuan Ding, Yuancong Jiang, Qiyi Zhang, Zhiwei Li, Jie Xiang, Jixuan Duan, Sheng Yan, Weilin Wang
Pages: 1042-1052
Published online on: 13 November 2018

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Low‑density lipoprotein promotes lymphatic metastasis of esophageal squamous cell carcinoma and is an adverse prognostic factor

Hongbin Deng, Tao Zhou, Xinkai Mo, Chengxin Liu, Yong Yin
Pages: 1053-1061
Published online on: 09 November 2018

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Correlation between tumor microenvironment‑associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer

Siyu Zhang, Wenqi Bai, Xunan Tong, Peng Bu, Jing Xu, Yanfeng Xi
Pages: 1062-1070
Published online on: 09 November 2018

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p53‑independent role of MYC mutant T58A in the proliferation and apoptosis of breast cancer cells

Dandan Jiang, Yuhua Song, Weihong Cao, Xingang Wang, Danni Jiang, Zhidong Lv, Zhaochuan Yang, Funian Li
Pages: 1071-1079
Published online on: 12 November 2018

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Identification of dysregulated microRNAs in canine malignant melanoma

Norio Ushio, Md Mahfuzur Rahman, Tadashi Maemura, Yu‑Chang Lai, Tomoko Iwanaga, Hiroaki Kawaguchi, Noriaki Miyoshi, Yasuyuki Momoi, Naoki Miura
Pages: 1080-1088
Published online on: 12 November 2018

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Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Lili Yang, Shuquan Zhang, Rui Gu, Chuangang Peng, Minfei Wu
Pages: 1089-1093
Published online on: 01 November 2018

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HNF1B expression regulates ECI2 gene expression, potentially serving a role in prostate cancer progression

Chao Dan, Haiyan Zhang, Wenjing Zeng, Li Huang, Xiaoxin Gong, Hao Li, Erjiang Yang, Li Wang, Qisheng Yao
Pages: 1094-1100
Published online on: 08 November 2018

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Perineural invasion as a prognostic risk factor in patients with early cervical cancer

Mei Tang, Qiuli Liu, Xueqing Yang, Ling Chen, Jinjin Yu, Xiaowei Qi, Yuan Wang
Pages: 1101-1107
Published online on: 07 November 2018

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Curcumin‑induced promoter hypermethylation of the mammalian target of rapamycin gene in multiple myeloma cells

Jiaqi Chen, Yongli Ying, Hongjun Zhu, Tingjun Zhu, Chunsheng Qu, Jinhong Jiang, Bingmu Fang
Pages: 1108-1114
Published online on: 05 November 2018

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Intestinal bacteria detected in cancer and adjacent tissue from patients with colorectal cancer

Chen‑Jian Liu, Yuan‑Lian Zhang, Yun Shang, Bian Wu, En Yang, Yi‑Yong Luo, Xiao‑Ran Li
Pages: 1115-1127
Published online on: 15 November 2018

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Association and clinical implication of the USP10 and MSH2 proteins in non‑small cell lung cancer

Zhi Zeng, Dan Li, Tao Yu, Yabing Huang, Honglin Yan, Lijuan Gu, Jingping Yuan
Pages: 1128-1138
Published online on: 15 November 2018

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Ginsenoside Rg3 suppresses the proliferation of prostate cancer cell line PC3 through ROS‑induced cell cycle arrest

Yanfei Peng, Ran Zhang, Xu Yang, Zhaiyi Zhang, Ning Kang, Liying Bao, Yongmei Shen, Hao Yan, Fang Zheng
Pages: 1139-1145
Published online on: 12 November 2018

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Sperm‑associated antigen 5 is a potential biomarker for poor prognosis in breast cancer

Xiaoli Zhou, Lizhou Jia, Yangyang Sun, Lingyun Xu, Xudong Wang, Qi Tang
Pages: 1146-1152
Published online on: 19 November 2018

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Occurrence of senescence-escaping cells in doxorubicin-induced senescence is enhanced by PD0332991, a cyclin-dependent kinase 4/6 inhibitor, in colon cancer HCT116 cells

Kunio Kitada, Fengling Pu, Masakazu Toi
Pages: 1153-1159
Published online on: 01 November 2018

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Effect of HMGN2 on proliferation and apoptosis of MCF-7 breast cancer cells Retraction in /10.3892/ol.2025.15005

Bo Fan, Sifeng Shi, Xiaofei Shen, Xiaolong Yang, Na Liu, Guixia Wu, Xiaojuan Guo, Ning Huang
Pages: 1160-1166
Published online on: 05 November 2018

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Effects of miR-101, miR-345 on HBV replication regulation and on the growth of liver cancer cells

Aikun Ding, Cuiyun Wang, Lihua Zhang
Pages: 1167-1171
Published online on: 05 November 2018

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MicroRNA‑183 and microRNA‑141 are potential risk factors for poor prognosis in patients with nasopharyngeal carcinoma

Junsheng Lian, Yujie Li, Min Yu
Pages: 1172-1176
Published online on: 01 November 2018

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Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen‑activated protein kinase signaling pathway

Peng Yin, Nanxin Zheng, Junfeng Dong, Chunyang Xu, Xiaomei Zhang, Guoshan Ding
Pages: 1177-1183
Published online on: 14 November 2018

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Comparison of values of CT and MRI imaging in the diagnosis of hepatocellular carcinoma and analysis of prognostic factors

Guibin Wang, Shicai Zhu, Xiukui Li
Pages: 1184-1188
Published online on: 12 November 2018

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MicroRNA-153 suppresses cell invasion by targeting SNAI1 and predicts patient prognosis in glioma

Wei Zhao, Chang-You Yin, Jing Jiang, Wei Kong, Hao Xu, Hongtao Zhang
Pages: 1189-1195
Published online on: 15 November 2018

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Article

Modern approaches to noninvasive diagnosis of malignant transformation of endometriosis

Hiroshi Kobayashi, Yuki Yamada, Naoki Kawahara, Kenji Ogawa, Chiharu Yoshimoto
Pages: 1196-1202
Published online on: 16 November 2018

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Article

Systemic transduction of p16INK4a antitumor peptide inhibits lung metastasis of the MBT‑2 bladder tumor cell line in mice

Toru Shimazui, Kazuhiro Yoshikawa, Ryutaro Ishitsuka, Takahiro Kojima, Shuya Kandori, Takayuki Yoshino, Jun Miyazaki, Kazuhiko Uchida, Hiroyuki Nishiyama
Pages: 1203-1210
Published online on: 01 November 2018

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Article

Cancerous inhibitor of protein phosphatase 2A regulates cisplatin resistance in ovarian cancer

Wanbin Li, Hongyan Zhang, Linqing Yang, Yunfei Wang
Pages: 1211-1216
Published online on: 01 November 2018

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Article

Naringenin has a chemoprotective effect in MDA‑MB‑231 breast cancer cells via inhibition of caspase‑3 and ‑9 activities Retraction in /10.3892/ol.2025.14923

Rui Wang, Junhai Wang, Tianfu Dong, Jun Shen, Xitao Gao, Jun Zhou
Pages: 1217-1222
Published online on: 15 November 2018

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Article

Deletion of C9orf53 promotes the growth of head and neck squamous cell carcinoma and is associated with poor prognosis of patients with head and neck squamous cell carcinoma

Guo Dong Wang, Jian Tao Huang, Yuan Liu, Yang Wu, Xiao Qing Chen, Yun Fu Zhao, Da Lin Wang
Pages: 1223-1228
Published online on: 08 November 2018

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Article

Long non‑coding RNA MIAT competitively binds miR‑150‑5p to regulate ZEB1 expression in osteosarcoma

Hao Jin, Xin Jin, Weiguang Chai, Zhiqiang Yin, Yang Li, Feng Dong, Wenbo Wang
Pages: 1229-1236
Published online on: 07 November 2018

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Article

SIRT6 inhibits proliferation and invasion in osteosarcoma cells by targeting N‑cadherin

Yi Gao, Yuxing Qu, Qi Zhou, Yong Ma
Pages: 1237-1244
Published online on: 08 November 2018

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Article

Oxygen‑laden mesenchymal stem cells enhance the effect of gastric cancer chemotherapy in vitro

Ya‑Li Zhou, Yu‑Min Li, Wen‑Ting He
Pages: 1245-1252
Published online on: 07 November 2018

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Case Report

The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report

Vittorio D'Aguanno, Massimo Ralli, Armando De Virgilio, Antonio Greco, Marco de Vincentiis
Pages: 1253-1256
Published online on: 16 November 2018

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Critical relevance of genomic gains of PRL‑3/EGFR/c‑myc pathway genes in liver metastasis of colorectal cancer

Toshimichi Tanaka, Takeshi Kaida, Keigo Yokoi, Satoru Ishii, Nobuyuki Nishizawa, Hiroshi Kawamata, Hiroshi Katoh, Takeo Sato, Takatoshi Nakamura, Masahiko Watanabe, Keishi Yamashita
Pages: 1257-1266
Published online on: 19 November 2018

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Inhibition effects of Yuxiao San combined with cisplatin on transplanted tumor growths via upregulation of nm‑23 and downregulation of K‑ras in Lewis lung cancer mice

Mo Tang, Shumei Wang, Yulin Wei, Jianti Fu
Pages: 1267-1273
Published online on: 07 November 2018

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Article

Intraocular schwannoma: A case series of 3 patients

Yang Yu, Yong Cheng, Kai Wang, Kunkun Sun, Danhua Shen, Jianhong Liang
Pages: 1274-1278
Published online on: 16 November 2018

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Comprehensive bioinformatics analysis of lncRNAs in gastric cancer

Dongdong Qi, Qiang Wang, Meiqing Wu, Xiong Zhang
Pages: 1279-1291
Published online on: 15 November 2018

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Periostin serves an important role in the pathogenesis of oral squamous cell carcinoma

Yuanyuan Kang, Xue Wang, Ying Zhang, Yan Sun
Pages: 1292-1298
Published online on: 01 November 2018

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Comparison of the 8th union for international cancer control lymph node staging system for gastric cancer with two other lymph node staging systems

Huihua Cao, Zhaoqing Tang, Zhan Yu, Qing Wang, Zhong Li, Qicheng Lu, Yugang Wu
Pages: 1299-1305
Published online on: 13 November 2018

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Association of matrix metalloproteinase‑9 and decorin expression with the infiltration of cervical cancer

Tomohito Tanaka, Yoshito Terai, Masahide Ohmichi
Pages: 1306-1312
Published online on: 15 November 2018

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Case Report

Conjunctival lymphomas in Japanese monozygotic twins: A case report

Naoya Ishibashi, Satoshi Sugaya, Hiromichi Takahashi, Haruna Nishimaki, Yoko Nakanishi, Yoshiaki Chinen, Toshiya Maebayashi
Pages: 1313-1319
Published online on: 16 November 2018

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Prospective analysis of the association between skeletal‑related events and quality of life in patients with advanced lung cancer (CSP‑HOR13)

Hiroshi Kunikane, Isao Yokota, Nobuyuki Katakami, Koji Takeda, Koichi Takayama, Toshiyuki Sawa, Hiroshi Saito, Masao Harada, Soichiro Yokota, Kiyoshi Ando, Yuko Saito, Yasuo Ohashi, Kenji Eguchi
Pages: 1320-1326
Published online on: 09 November 2018

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Article

miR‑106a contributes to prostate carcinoma progression through PTEN

Ji Lu, Xupeng Mu, Qinan Yin, Kebang Hu
Pages: 1327-1332
Published online on: 14 November 2018

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Article

PTEN inhibits non‑small cell lung cancer cell growth by promoting G0/G1 arrest and cell apoptosis

Libao Liu, Lei Huang, Jinyuan He, Songwang Cai, Yimin Weng, Shaohong Huang, Shaohong Ma
Pages: 1333-1340
Published online on: 16 November 2018

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Article

Outcomes of stage II‑IV upper‑tract urothelial carcinoma and adjuvant chemotherapy for locally advanced cancer

Yi‑Huei Chang, Po‑Jen Hsiao, Guang‑Heng Chen, Ching‑Chan Lin, Chao‑Hsiang Chang, Hsi‑Chin Wu, Chi‑Ping Huang, Chi‑Rei Yang, Su‑Peng Yeh
Pages: 1341-1348
Published online on: 07 November 2018

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Article

Circulating immune biomarkers as predictors of the response to pembrolizumab and weekly low dose carboplatin and paclitaxel in NSCLC and poor PS: An interim analysis

Marcelo Bonomi, Tamjeed Ahmed, Safoa Addo, Mitra Kooshki, Dario Palmieri, Beverly J. Levine, Jimmy Ruiz, Stefan Grant, William J. Petty, Pierre L. Triozzi
Pages: 1349-1356
Published online on: 19 November 2018

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Article

Variation of nicotinic subtype α7 and muscarinic subtype M3 acetylcholine receptor expression in three main types of leukemia

Tawit Suriyo, Sadudee Chotirat, Chirayu U. Auewarakul, Karnjana Chaiyot, Orathai Promsuwicha, Jutamaad Satayavivad
Pages: 1357-1362
Published online on: 05 November 2018

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Article

miR‑142‑5p suppresses proliferation and promotes apoptosis of human osteosarcoma cell line, HOS, by targeting PLA2G16 through the ERK1/2 signaling pathway

Deliang Cheng, Jiageng Li, Lijun Zhang, Leiming Hu
Pages: 1363-1371
Published online on: 15 November 2018

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Article

Triptolide suppresses the proliferation and induces the apoptosis of nasopharyngeal carcinoma cells via the PI3K/Akt pathway

Mi Wang, Bo Chen , Liang Chai
Pages: 1372-1378
Published online on: 19 November 2018

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Article

MicroRNA expression in pediatric intracranial ependymomas and their potential value for tumor grading

Šimon Cipro, Marie Belhajová, Tomáš Eckschlager, Josef Zámečník
Pages: 1379-1383
Published online on: 12 November 2018

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Article

Treatment package time predicts cancer‑specific survival and distant metastasis in laryngeal cancer

Hidenori Suzuki, Hoshino Terada, Nobuhiro Hanai, Daisuke Nishikawa, Yusuke Koide, Shintaro Beppu, Takeshi Kodaira, Hiroyuki Tachibana, Yutaro Koide, Hiroshi Tanaka, Yasuhisa Hasegawa
Pages: 1384-1390
Published online on: 05 November 2018

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January-2026 Volume 31 Issue 1

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CiteScore: 4.6

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

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Article Number: 41
Published online on: 24 November 2025

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Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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