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Article

An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma

  • Authors:
    • Rei Suzuki
    • Tadayuki Takagi
    • Takuto Hikichi
    • Mitsuru Sugimoto
    • Naoki Konno
    • Hiroyuki Asama
    • Ko Watanabe
    • Jun Nakamura
    • Shigeru Marubashi
    • Hiromasa Ohira
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima 960‑1295, Japan, Department of Endoscopy, Fukushima Medical University Hospital, Fukushima 960‑1295, Japan, Department of Hepato‑Biliary‑Pancreatic and Transplant Surgery, Fukushima Medical University School of Medicine, Fukushima 960‑1295, Japan
  • Pages: 587-593
    |
    Published online on: October 26, 2018
       https://doi.org/10.3892/ol.2018.9626
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Abstract

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an aggressive course; therefore, it was hypothesized that waiting times during disease management may serve as a prognostic factor for patients with PDAC. Data for all patients with PDAC who received treatment in Fukushima Medical University Hospital were collected. Median disease‑free survival and overall survival time were calculated using the Kaplan‑Meier method and utilized as cut‑off points to divide the patients into 2 groups: A short and a long survival group. Clinical characteristics, including waiting times, the detection‑to‑diagnosis waiting time and the diagnosis‑to‑treatment waiting time, were compared between the 2 survival groups. A total of 149 patients were included in the present study. Among the 72 patients who underwent chemotherapy, no significant differences between the 2 survival groups regarding waiting times were identified; however, the proportion of patients with locally advanced disease and the administration of combination chemotherapy were significantly associated with increased survival. Additionally, no significant differences in the waiting times between the 2 survival groups were identified when evaluating the 79 patients who underwent surgical resection. In conclusion, the results of the present study indicated that detection‑to‑diagnosis and diagnosis‑to‑treatment waiting times do not influence the prognosis of patients with PDAC.
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Copy and paste a formatted citation
Spandidos Publications style
Suzuki R, Takagi T, Hikichi T, Sugimoto M, Konno N, Asama H, Watanabe K, Nakamura J, Marubashi S, Ohira H, Ohira H, et al: An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma. Oncol Lett 17: 587-593, 2019.
APA
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H. ... Ohira, H. (2019). An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma. Oncology Letters, 17, 587-593. https://doi.org/10.3892/ol.2018.9626
MLA
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H., Watanabe, K., Nakamura, J., Marubashi, S., Ohira, H."An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma". Oncology Letters 17.1 (2019): 587-593.
Chicago
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H., Watanabe, K., Nakamura, J., Marubashi, S., Ohira, H."An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma". Oncology Letters 17, no. 1 (2019): 587-593. https://doi.org/10.3892/ol.2018.9626
Copy and paste a formatted citation
x
Spandidos Publications style
Suzuki R, Takagi T, Hikichi T, Sugimoto M, Konno N, Asama H, Watanabe K, Nakamura J, Marubashi S, Ohira H, Ohira H, et al: An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma. Oncol Lett 17: 587-593, 2019.
APA
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H. ... Ohira, H. (2019). An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma. Oncology Letters, 17, 587-593. https://doi.org/10.3892/ol.2018.9626
MLA
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H., Watanabe, K., Nakamura, J., Marubashi, S., Ohira, H."An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma". Oncology Letters 17.1 (2019): 587-593.
Chicago
Suzuki, R., Takagi, T., Hikichi, T., Sugimoto, M., Konno, N., Asama, H., Watanabe, K., Nakamura, J., Marubashi, S., Ohira, H."An observation study of the prognostic effect of waiting times in the management of pancreatic ductal adenocarcinoma". Oncology Letters 17, no. 1 (2019): 587-593. https://doi.org/10.3892/ol.2018.9626
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