|
1
|
Vayghan HJ, Ghadimi SS and Nourazarian AR:
Preventive and therapeutic roles of ginseng-focus on colon cancer.
Asian Pac J Cancer Prev. 15:585–588. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Sun M, Ye Y, Xiao L, Duan X, Zhang Y and
Zhang H: Anticancer effects of ginsenoside Rg3 (Review). Int J Mol
Med. 39:507–518. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Sun HY, Lee JH, Han YS, Yoon YM, Yun CW,
Kim JH, Song YS and Lee SH: Pivotal roles of ginsenoside rg3 in
tumor apoptosis through regulation of reactive oxygen species.
Anticancer Res. 36:4647–4654. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhang F, Li M, Wu X, Hu Y, Cao Y, Wang X,
Xiang S, Li H, Jiang L, Tan Z, et al: 20(S)-ginsenoside Rg3
promotes senescence and apoptosis in gallbladder cancer cells via
the p53 pathway. Drug Des Devel Ther. 9:3969–3987. 2015.PubMed/NCBI
|
|
5
|
Zheng X, Chen W, Hou H, Li J, Li H, Sun X,
Zhao L and Li X: Ginsenoside 20(S)-Rg3 induced autophagy to inhibit
migration and invasion of ovarian cancer. Biomed Pharmacother.
85:620–626. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Junmin S, Hongxiang L, Zhen L, Chao Y and
Chaojie W: Ginsenoside Rg3 inhibits colon cancer cell migration by
suppressing nuclear factor kappa B activity. J Tradit Chin Med.
35:440–444. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Tian L, Shen D, Li X, Shan X, Wang X, Yan
Q and Liu J: Ginsenoside Rg3 inhibits epithelial-mesenchymal
transition (EMT) and invasion of lung cancer by down-regulating
FUT4. Oncotarget. 7:1619–1632. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wang J, Tian L, Khan MN, Zhang L, Chen Q,
Zhao Y, Yan Q, Fu L and Liu J: Ginsenoside Rg3 sensitizes hypoxic
lung cancer cells to cisplatin via blocking of NF-κB mediated
epithelial-mesenchymal transition and stemness. Cancer Lett.
415:73–85. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Jiang J, Yuan Z, Sun Y, Bu Y, Li W and Fei
Z: Ginsenoside Rg3 enhances the anti-proliferative activity of
erlotinib in pancreatic cancer cell lines by downregulation of
EGFR/PI3K/Akt signaling pathway. Biomed Pharmacother. 96:619–625.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Barnett CM, Nielson CM, Shannon J, Chan
JM, Shikany JM, Bauer DC, Hoffman AR, Barrett-Connor E, Orwoll E
and Beer TM: Serum 25-OH vitamin D levels and risk of developing
prostate cancer in older men. Cancer Causes Control. 21:1297–1303.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Pan XY, Guo H, Han J, Hao F, An Y, Xu Y,
Xiaokaiti Y, Pan Y and Li XJ: Ginsenoside Rg3 attenuates cell
migration via inhibition of aquaporin 1 expression in PC-3M
prostate cancer cells. Eur J Pharmacol. 683:27–34. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kim SM, Lee SY, Cho JS, Son SM, Choi SS,
Yun YP, Yoo HS, Yoon DY, Oh KW, Han SB and Hong JT: Combination of
ginsenoside Rg3 with docetaxel enhances the susceptibility of
prostate cancer cells via inhibition of NF-kappaB. Eur J Pharmacol.
631:1–9. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liu WK, Xu SX and Che CT:
Anti-proliferative effect of ginseng saponins on human prostate
cancer cell line. Life Sci. 67:1297–1306. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Sanz A: Mitochondrial reactive oxygen
species: Do they extend or shorten animal lifespan? Biochim Biophys
Acta. 1857:1116–1126. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Park HM, Kim SJ, Kim JS and Kang HS:
Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced
apoptosis in hepatoma cells through mitochondrial signaling
pathways. Food Chem Toxicol. 50:2736–2741. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kim BM, Kim DH, Park JH, Na HK and Surh
YJ: Ginsenoside Rg3 induces apoptosis of human breast cancer
(MDA-MB-231) cells. J Cancer Prev. 18:177–185. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Choi YJ, Lee HJ, Kang DW, Han IH, Choi BK
and Cho WH: Ginsenoside Rg3 induces apoptosis in the U87MG human
glioblastoma cell line through the MEK signaling pathway and
reactive oxygen species. Oncol Rep. 30:1362–1370. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Xia T, Wang YN, Zhou CX, Wu LM, Liu Y,
Zeng QH, Zhang XL, Yao JH, Wang M and Fang JP: Ginsenoside Rh2 and
Rg3 inhibit cell proliferation and induce apoptosis by increasing
mitochondrial reactive oxygen species in human leukemia jurkat
cells. Mol Med Rep. 15:3591–3598. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Wang C, Du X, Yang R, Liu J, Xu D, Shi J,
Chen L, Shao R, Fan G, Gao X, et al: The prevention and treatment
effects of tanshinone IIA on oestrogen/androgen-induced benign
prostatic hyperplasia in rats. J Steroid Biochem Mol Biol.
145:28–37. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Udensi UK and Tchounwou PB: Oxidative
stress in prostate hyperplasia and carcinogenesis. J Exp Clin
Cancer Res. 35:1392016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Paschos A, Pandya R, Duivenvoorden WC and
Pinthus JH: Oxidative stress in prostate cancer: Changing research
concepts towards a novel paradigm for prevention and therapeutics.
Prostate Cancer Prostatic Dis. 16:217–225. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Mohsenzadegan M, Seif F, Farajollahi MM
and Khoshmirsafa M: Anti-oxidants as chemopreventive agents in
prostate cancer: A gap between preclinical and clinical studies.
Recent Pat Anticancer Drug Discov. 13:224–239. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Ramamoorthy V, Rubens M, Saxena A and
Shehadeh N: Selenium and vitamin E for prostate
cancer-justifications for the SELECT study. Asian Pac J Cancer
Prev. 16:2619–2627. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Assi M: The differential role of reactive
oxygen species in early and late stages of cancer. Am J Physiol
Regul Integr Comp Physiol. 313:R646–R653. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Jayakumar S, Kunwar A, Sandur SK, Pandey
BN and Chaubey RC: Differential response of DU145 and PC3 prostate
cancer cells to ionizing radiation: Role of reactive oxygen
species, GSH and Nrf2 in radiosensitivity. Biochim Biophys Acta.
1840:485–494. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Nogueira V, Patra KC and Hay N: Selective
eradication of cancer displaying hyperactive Akt by exploiting the
metabolic consequences of Akt activation. Elife. 7:e322132018.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Isebaert SF, Swinnen JV, McBride WH and
Haustermans KM: Insulin-like growth factor-type 1 receptor
inhibitor NVP-AEW541 enhances radiosensitivity of PTEN wild-type
but not PTEN-deficient human prostate cancer cells. Int J Radiat
Oncol Biol Phys. 81:239–247. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Peng Y, Zhang R, Kong L, Shen Y, Xu D,
Zheng F, Liu J, Wu Q, Jia B and Zhang J: Ginsenoside Rg3 inhibits
the senescence of prostate stromal cells through down-regulation of
interleukin 8 expression. Oncotarget. 8:64779–64792.
2017.PubMed/NCBI
|
