The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report

D'Aguanno,Vittorio; Ralli,Massimo; De Virgilio,Armando; Greco,Antonio; de Vincentiis,Marco

doi:10.3892/ol.2018.9717

January-2019 Volume 17 Issue 1

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January-2019 Volume 17 Issue 1

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Case Report

The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report

Authors:
- Vittorio D'Aguanno
- Massimo Ralli
- Armando De Virgilio
- Antonio Greco
- Marco de Vincentiis
View Affiliations / Copyright

Affiliations: Department of Sense Organs, Sapienza University of Rome, Rome I‑00186, Italy, Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome I‑00186, Italy, Humanitas Clinical and Research Center, Milan I‑20089, Italy
Pages: 1253-1256
|
Published online on: November 16, 2018

https://doi.org/10.3892/ol.2018.9717
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Abstract

Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's tumour, is an unusual vascular lesion characterized by the proliferation of endothelial cells. The principal significance of IPEH is its clinical and radiological resemblance to angiosarcoma, resulting in a potential misdiagnosis and overtreatment. The aim of the present study is to report a rare case of IPEH of the right maxillary sinus, focusing on the radiological and histopathological features of the neoplasm and their role in the differential diagnosis with angiosarcoma. Herein we present a case of a 67‑year‑old woman with history of right‑sided nasal obstruction. A computed tomography scan indicated opacity in the right maxillary sinus and significant bony erosion, and an magnetic resonance imaging revealed a highly vascularized polylobed neoplasm, suggesting a malignant neoplasm. The mass was removed surgically through a combined open and endoscopic approach. A perioperative biopsy excluded malignancy and histological examination was consistent with IPEH. IPEH in the sinonasal cavity is an extremely rare condition in which differential diagnosis serves a central role due to its close clinical and radiological resemblance to angiosarcoma. Awareness of IPEH is recommended for a correct diagnosis, and in order to avoid unnecessarily aggressive treatment.

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Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report

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