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Article

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

  • Authors:
    • Hao Yu
    • Cui Feng
    • Zi Wang
    • Jianjun Li
    • Yanchun Wang
    • Xuemei Hu
    • Zhen Li
    • Yaqi Shen
    • Daoyu Hu
  • View Affiliations / Copyright

    Affiliations: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China
  • Pages: 1451-1457
    |
    Published online on: June 5, 2019
       https://doi.org/10.3892/ol.2019.10441
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Abstract

Patients with chronic inflammatory bowel disease have an increased risk of colorectal cancer, and the differentiation between neoplastic and inflammatory lesions often poses a clinical dilemma. The aim of the present study was to investigate whether diffusion‑weighted (DW) magnetic resonance (MR) enterography with ultra‑high b‑value facilitates the identification of neoplastic lesions in the ileocecal region. A total of 76 patients (22 patients with neoplasms, 26 inflammatory lesions and 28 normal subjects) from 292 cases of suspected bowel disorders were included in the present study. All patients were examined with conventional MR enterography and DW imaging (DWI) with seven different b‑values (400, 600, 800, 1,000, 1,200, 1,500 and 3,000 sec/mm2) in a 3T MR scanner. DWI scans with different b‑values were analyzed independently by two radiologists for the presence of ileocecal lesions. The signal intensity of the majority of inflammatory lesions and normal bowel segments gradually decreased to the background intensity with increasing b‑values; however, neoplastic lesions demonstrated relative hyperintensity compared with the background. In addition, ~76% of the positive findings from b=3,000 sec/mm2 DWI were neoplasms. In conclusion, a lesion with consistently high signal intensity from DWI images with b‑values increasing to 3,000 sec/mm2 indicated the presence of neoplasms. The results suggested that ultra‑high b‑value (3,000 sec/mm2) imaging may aid the clinical differentiation of neoplasms from benign conditions.
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Copy and paste a formatted citation
Spandidos Publications style
Yu H, Feng C, Wang Z, Li J, Wang Y, Hu X, Li Z, Shen Y and Hu D: Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging. Oncol Lett 18: 1451-1457, 2019.
APA
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X. ... Hu, D. (2019). Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging. Oncology Letters, 18, 1451-1457. https://doi.org/10.3892/ol.2019.10441
MLA
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X., Li, Z., Shen, Y., Hu, D."Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging". Oncology Letters 18.2 (2019): 1451-1457.
Chicago
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X., Li, Z., Shen, Y., Hu, D."Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging". Oncology Letters 18, no. 2 (2019): 1451-1457. https://doi.org/10.3892/ol.2019.10441
Copy and paste a formatted citation
x
Spandidos Publications style
Yu H, Feng C, Wang Z, Li J, Wang Y, Hu X, Li Z, Shen Y and Hu D: Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging. Oncol Lett 18: 1451-1457, 2019.
APA
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X. ... Hu, D. (2019). Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging. Oncology Letters, 18, 1451-1457. https://doi.org/10.3892/ol.2019.10441
MLA
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X., Li, Z., Shen, Y., Hu, D."Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging". Oncology Letters 18.2 (2019): 1451-1457.
Chicago
Yu, H., Feng, C., Wang, Z., Li, J., Wang, Y., Hu, X., Li, Z., Shen, Y., Hu, D."Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging". Oncology Letters 18, no. 2 (2019): 1451-1457. https://doi.org/10.3892/ol.2019.10441
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