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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2019 Volume 18 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Fusobacterium nucleatum‑positive colorectal cancer (Review)

Zhenhua Yang, Guang Ji
Pages: 975-982
Published online on: 04 June 2019

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Review Open Access

ST6GAL1: A key player in cancer (Review)

Rebecca Garnham, Emma Scott, Karen E. Livermore, Jennifer Munkley
Pages: 983-989
Published online on: 07 June 2019

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Article Open Access

Primary osteosarcoma in elderly patients: A report of three cases

Qiang Xu, Tian Gao, Bin Zhang, Jin Zeng, Min Dai
Pages: 990-996
Published online on: 07 June 2019

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Article Open Access

Clinical significance and comparison of flotillin 1 expression in left and right colon cancer

Nadia Baig, Zequn Li, Jing Lu, Haibin Chen, Songyang Yu, Tianen Li, Zhaojian Niu, Jun Niu
Pages: 997-1004
Published online on: 27 May 2019

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Article Open Access

LncRNA HAND2‑AS1 overexpression inhibits cancer cell proliferation in melanoma by downregulating ROCK1

Pengcheng Liu, Ruili Du, Xin Yu
Pages: 1005-1010
Published online on: 27 May 2019

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Article Open Access

A novel CpG island methylation panel predicts survival in lung adenocarcinomas

Pingzhao Yan, Xiaohua Yang, Jianhua Wang, Shichang Wang, Hong Ren
Pages: 1011-1022
Published online on: 04 June 2019

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Article Open Access

Integrated bioinformatics analysis to identify 15 hub genes in breast cancer

Haoxuan Jin, Xiaoyan Huang, Kang Shao, Guibo Li, Jian Wang, Huanming Yang, Yong Hou
Pages: 1023-1034
Published online on: 30 May 2019

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Article Open Access

Mechanism of cadmium poisoning on testicular injury in mice

Yaping Ren, Wenhua Shao, Lijun Zuo, Wei Zhao, Haizhang Qin, Yingjie Hua, Dejie Lu, Chao Mi, Sien Zeng, Liao Zu
Pages: 1035-1042
Published online on: 30 May 2019

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Article Open Access

MicroRNA‑145 inhibits proliferation and induces apoptosis in human prostate carcinoma by upregulating long non‑coding RNA GAS5

Xin Xie, Jun Dai, Xin Huang, Chen Fang, Wei He
Pages: 1043-1048
Published online on: 30 May 2019

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Article Open Access

MYH9 overexpression correlates with clinicopathological parameters and poor prognosis of epithelial ovarian cancer

Longyang Liu, Juanjuan Yi, Xiaojie Deng, Jianhuan Yuan, Beixian Zhou, Zhongqiu Lin, Zhaoyang Zeng
Pages: 1049-1056
Published online on: 27 May 2019

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Article Open Access

A Surveillance, Epidemiology and End Results database analysis of the prognostic value of organ‑specific metastases in patients with advanced prostatic adenocarcinoma

Yuyou Deng, Ran Bi, Zhenhua Zhu, Shengxian Li, Bo Xu, Wakeel Ahmad Rather, Chunxi Wang
Pages: 1057-1070
Published online on: 07 June 2019

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Article Open Access

Assessment of the therapeutic accuracy of cone beam computed tomography‑guided nasopharyngeal carcinoma radiotherapy

Jiabin Liu, Khumbula Maitireazvo Lyman, Zhenhua Ding, Liang Zhou
Pages: 1071-1080
Published online on: 30 May 2019

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Article Open Access

Profiling of prognostic alternative splicing in melanoma

Fu‑Chao Ma, Rong‑Quan He, Peng Lin, Jin‑Cai Zhong, Jie Ma, Hong Yang, Xiao‑Hua Hu, Gang Chen
Pages: 1081-1088
Published online on: 07 June 2019

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Article Open Access

Conditional survival analysis of four treatment strategies for patients with stage I non‑small cell lung cancer

Yicheng Liang, Xiaoxi Fan, Yunpeng Bai, Dejian Huang, Chunlu Yang
Pages: 1089-1098
Published online on: 30 May 2019

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Article Open Access

CXCL12 is associated with FoxP3+ tumor‑infiltrating lymphocytes and affects the survival of patients with oral squamous cell carcinoma

Bowen Zhang, Chenzhou Wu, Zhuoyuan Zhang, Kaixiao Yan, Chunjie Li, Yi Li, Longjiang Li
Pages: 1099-1106
Published online on: 30 May 2019

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Article Open Access

Integral analyses of survival‑related long non‑coding RNA MIR210HG and its prognostic role in colon cancer

Zhaohui Ruan, Zixuan Xu, Zhaozhi Li, Yanni Lv
Pages: 1107-1116
Published online on: 04 June 2019

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Article Open Access

Identification of key genes and pathways downstream of the β‑catenin‑TCF7L1 complex in pancreatic cancer cells using bioinformatics analysis

Yi‑Hang Yuan, Jian Zhou, Yan Zhang, Meng‑Dan Xu, Jing Wu, Wei Li, Meng‑Yao Wu, Dao‑Ming Li
Pages: 1117-1132
Published online on: 06 June 2019

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Case Report Open Access

Cystic and solitary nodular pulmonary metastases in a patient with low‑grade endometrial stromal sarcoma: A case report and literature review

Yang Xu, Zhi‑Xin Liang, Jun‑Tang Guo, Xin Su, Yun‑Long Lu, Xi‑Zhou Guan
Pages: 1133-1144
Published online on: 30 May 2019

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Article Open Access

Comprehensive analysis of differentially expressed long non‑coding RNAs in non‑small cell lung cancer

Wenyong Zhou, Tao Liu, Gaowa Saren, Li Liao, Wentao Fang, Heng Zhao
Pages: 1145-1156
Published online on: 30 May 2019

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Article Open Access

Expression of ERCC1 and TYMS in colorectal cancer patients and the predictive value of chemotherapy efficacy

Hong Jiang, Baosong Li, Fengxia Wang, Chong Ma, Tao Hao
Pages: 1157-1162
Published online on: 23 May 2019

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Article Open Access

Upregulation of nectin‑4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer

Jinxiu Zhang, Kecheng Liu, Peng Peng, Siman Li, Zhe Ye, Yingjie Su, Shiquan Liu, Mengbin Qin, Jiean Huang
Pages: 1163-1170
Published online on: 30 May 2019

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Article Open Access

CA916798 gene expression is associated with multidrug resistance and predicts progression‑free survival in patients with lung cancer

Hailing Duan, Zaixing Yang, Lan Liang, Xiangdong Zhou
Pages: 1171-1178
Published online on: 04 June 2019

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Article Open Access

Identification of a miRNA‑mRNA network associated with lymph node metastasis in colorectal cancer

Qiang Ju, Yan‑Jie Zhao, Yong Dong, Cong Cheng, Shaoqiang Zhang, Yuanming Yang, Ping Li, Dongmei Ge, Bo Sun
Pages: 1179-1188
Published online on: 07 June 2019

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Article Open Access

Effect of CD133 overexpression on bone metastasis in prostate cancer cell line LNCaP

Hong Moon Sohn, Bora Kim, Mineon Park, Young Jong Ko, Yeon Hee Moon, Jae Myung Sun, Byung‑Cheol Jeong, Young Wook Kim, Wonbong Lim
Pages: 1189-1198
Published online on: 06 June 2019

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Article Open Access

Interactive online consensus survival tool for esophageal squamous cell carcinoma prognosis analysis

Qiang Wang, Fengling Wang, Jiajia Lv, Junfang Xin, Longxiang Xie, Wan Zhu, Yitai Tang, Yongqiang Li, Xiaofang Zhao, Yunlong Wang, Xianzhe Li, Xiangqian Guo
Pages: 1199-1206
Published online on: 05 June 2019

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Article Open Access

Weighted correlation network analysis of triple‑negative breast cancer progression: Identifying specific modules and hub genes based on the GEO and TCGA database

Lei Lan, Bin Xu, Qu Chen, Jingting Jiang, Yueping Shen
Pages: 1207-1217
Published online on: 27 May 2019

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Article Open Access

lncRNA‑CCHE1 is involved in migration and invasion but not in proliferation of pancreatic adenocarcinoma cells possibly by interacting with ROCK1

Xiang Jin, Liping Ye, Minhua Lin, Binbin Gu, Jun Wang, Yequn He, Weilin Li
Pages: 1218-1224
Published online on: 30 May 2019

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Article Open Access

Knockdown of long non‑coding RNA PVT1 inhibits the proliferation of Raji cells through cell cycle regulation

Chanli Zheng, Yu Xiao, Yangqiu Li, Dongmei He
Pages: 1225-1234
Published online on: 07 June 2019

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Article Open Access

Six‑mRNA risk score system and nomogram constructed for patients with ovarian cancer

Qianqian Wang, Zhuwu Lu, Jinqi Ma, Qingsong Zhang, Ni Wang, Li Qian, Jun Zhang, Chen Chen, Bei Lu
Pages: 1235-1245
Published online on: 27 May 2019

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Article Open Access

Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF‑7

Benjaporn Buranrat, Supavadee Bootha
Pages: 1246-1258
Published online on: 05 June 2019

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Article Open Access

Sphingosine kinase‑1 predicts overall survival outcomes in non‑small cell lung cancer patients treated with carboplatin and navelbine

Mariam Gachechiladze, Tomáš Tichý, Vítězslav Kolek, Ivona Grygárková, Jiří Klein, Giorgi Mgebrishvili, Gvantsa Kharaishvili, Mária Janíková, Petra Smičková, Lucia Cierna, Stuart Pitson, Marie‑Lise Maddelein, Olivier Cuvillier, Jozef Škarda
Pages: 1259-1266
Published online on: 07 June 2019

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Article Open Access

Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high‑incidence area of northern China

Fang Zhao, Jing‑Fen Su, Shu‑Min Lun, Yong‑Jie Hou, Li‑Juan Duan, Neng‑Chao Wang, Fang‑Fang Shen, Yao‑Wen Zhang, Zhao‑Wei Gao, Jing Li, Xian‑Juan Du, Fu‑You Zhou
Pages: 1267-1277
Published online on: 07 June 2019

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Article Open Access

Hypermethylation of the PTTG1IP promoter leads to low expression in early‑stage non‑small cell lung cancer

Xiaoming Tan, Sufen Zhang, Huifang Gao, Wanhong He, Minjie Xu, Qihan Wu, Xiaohua Ni, Handong Jiang
Pages: 1278-1286
Published online on: 27 May 2019

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Article Open Access

Dysregulation of DNA methylation patterns may identify patients with breast cancer resistant to endocrine therapy: A predictive classifier based on differentially methylated regions

Fan Zhang, Yukun Cui
Pages: 1287-1303
Published online on: 27 May 2019

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Article Open Access

Prognostic value of ATAD3 gene cluster expression in hepatocellular carcinoma

Xiaoling Liu, Gang Li, Liang Ai, Qiuwen Ye, Tingdong Yu, Burong Yang
Pages: 1304-1310
Published online on: 07 June 2019

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Article Open Access

Comparison of single utility port video-assisted thoracoscopic surgery (VATS) and three-port VATS for non-small cell lung cancer

Zhongrui Ye, Bo Zhang, Yu Chen, Jiang Lin
Pages: 1311-1317
Published online on: 22 May 2019

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Article Open Access

Association of miR‑100 expression with clinicopathological features and prognosis of patients with lung cancer

Xiaolong Ma, Jiaqi Zhou, Hongyan Mo, Ying Ying
Pages: 1318-1322
Published online on: 22 May 2019

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Article Open Access

Long non‑coding RNA HAND2‑AS1 targets glucose metabolism and inhibits cancer cell proliferation in osteosarcoma

Shunguang Chen, Xiaoming Xu, Shengjun Lu, Biao Hu
Pages: 1323-1329
Published online on: 07 June 2019

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Article Open Access

Demethylation of SOCS1 mediates its abnormally high expression in ovarian cancer

Xuejiao Li, Chuimiao Kong, Yuchun Fan, Jia Liu, Weiyuan Lu, Caiyun Meng, Aimei Li, Aixia Zhai, Bingqing Yan, Wuqi Song, Xu Han
Pages: 1330-1336
Published online on: 07 June 2019

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Article Open Access

SNHG20/miR‑140‑5p/NDRG3 axis contributes to 5‑fluorouracil resistance in gastric cancer

Jie Yu, Jie Shen, Xu Qiao, Longlei Cao, Zhangling Yang, Hui Ye, Changlei Xi, Qichang Zhou, Peiyun Wang, Zhilin Gong
Pages: 1337-1343
Published online on: 05 June 2019

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Article Open Access

Analysis of clinical characteristics of macrophage capping protein (CAPG) gene expressed in glioma based on TCGA data and clinical experiments

Qiang Fu, Mahati Shaya, Shaoshan Li, Yalikun Kugeluke, Yisireyili Dilimulati, Bo Liu, Qingjiu Zhou
Pages: 1344-1350
Published online on: 23 May 2019

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Article Open Access

Ki‑67 and P16 proteins in cervical cancer and precancerous lesions of young women and the diagnostic value for cervical cancer and precancerous lesions

Qin Shi, Ling Xu, Rong Yang, Yaping Meng, Lihua Qiu
Pages: 1351-1355
Published online on: 03 June 2019

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Article Open Access

Clinical significance of aberrant DEUP1 promoter methylation in hepatocellular carcinoma

Qiwen Yu, Shengli Cao, Hongwei Tang, Jie Li, Wenzhi Guo, Shuijun Zhang
Pages: 1356-1364
Published online on: 30 May 2019

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Article Open Access

Bmi-1 in gallbladder carcinoma: Clinicopathology and mechanism of regulation of human gallbladder carcinoma proliferation

Kai Jiao, Weijiao Jiang, Chunyang Zhao, Dewang Su, Haomin Zhang
Pages: 1365-1371
Published online on: 28 May 2019

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Article Open Access

Glucose metabolism changes during the development and progression of oral tongue squamous cell carcinomas

Keiichiro Nakazato, Kaoru Mogushi, Kou Kayamori, Maiko Tsuchiya, Ken‑Ichiro Takahashi, Jun Sumino, Yasuyuki Michi, Tetsuya Yoda, Narikazu Uzawa
Pages: 1372-1380
Published online on: 30 May 2019

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Article Open Access

A five‑gene signature to predict the overall survival time of patients with esophageal squamous cell carcinoma

Wenwu He, Qunlun Yan, Liangmin Fu, Yongtao Han
Pages: 1381-1387
Published online on: 07 June 2019

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Article Open Access

Expressions of 10 genes as candidate predictors of recurrence in stage III colon cancer patients receiving adjuvant oxaliplatin‑based chemotherapy

Kensuke Kumamoto, Yutaka Nakachi, Yosuke Mizuno, Masaru Yokoyama, Keiichiro Ishibashi, Chihiro Kosugi, Keiji Koda, Michiya Kobayashi, Kohji Tanakaya, Toshio Matsunami, Hidetaka Eguchi, Yasushi Okazaki, Hideyuki Ishida
Pages: 1388-1394
Published online on: 05 June 2019

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Article Open Access

Diagnostic value and clinical significance of ultrasound combined with CT in cystic renal cell carcinoma

Minghui Sun, Chao Wang, Fei Jiang, Xiuhong Fang, Bingcheng Guo
Pages: 1395-1401
Published online on: 30 May 2019

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Article

Programmed cell death factor 4 enhances the chemosensitivity of colorectal cancer cells to Taxol

Daqing Wang, Qianqian Hou, Lingjun Zhao, Jun Gao, Yang Xiao, Anhua Wang
Pages: 1402-1408
Published online on: 27 May 2019

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Article

Carboxamide derivatives induce apoptosis in the U251 glioma cell line

Tao Yan, Junxue Zhuang, Lu He
Pages: 1409-1414
Published online on: 04 June 2019

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Article

Clinical significance of enhancer of zeste homolog 2 and histone deacetylases 1 and 2 expression in peripheral T‑cell lymphoma

Huilai Zhang, Huijuan Lv, Xiaohui Jia, Ge Hu, Lingzhe Kong, Tingting Zhang, Linyu Li, Yi Pan, Qiongli Zhai, Bin Meng, Xi Wang, Huaqing Wang, Xianhuo Wang
Pages: 1415-1423
Published online on: 30 May 2019

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Article

Increased frequency of regulatory T cells in the peripheral blood of patients with endometrioid adenocarcinoma

Li Li, Yinghua Li, Zhuomin Yin, Jing Zhu, Dingding Yan, Hanmei Lou
Pages: 1424-1430
Published online on: 07 June 2019

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Article

Correlation and expression analysis of hypoxia‑inducible factor 1α, glucose transporter 1 and lactate dehydrogenase 5 in human gastric cancer

Lang‑Song Hao, Qi Liu, Chuan Tian, Dong‑Xing Zhang, Bo Wang, Dong‑Xu Zhou, Zhao‑Peng Li, Zhi‑Xiang Yuan
Pages: 1431-1441
Published online on: 07 June 2019

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Article

Significance of cyclooxygenase‑2, prostaglandin E2 and CD133 levels in sunitinib‑resistant renal cell carcinoma

Lei Luo, Ye Liang, Xuemei Ding, Xiaocheng Ma, Guiming Zhang, Lijiang Sun
Pages: 1442-1450
Published online on: 06 June 2019

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Article

Potential of diffusion‑weighted imaging in magnetic resonance enterography to identify neoplasms in the ileocecal region: Use of ultra‑high b‑value diffusion‑weighted imaging

Hao Yu, Cui Feng, Zi Wang, Jianjun Li, Yanchun Wang, Xuemei Hu, Zhen Li, Yaqi Shen, Daoyu Hu
Pages: 1451-1457
Published online on: 05 June 2019

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Article

Programmed death‑ligand 1 expression is an unfavorable prognostic factor of hepatocellular carcinoma after archiving sustained virologic response for hepatitis C virus infection

Reiichiro Kondo, Jun Akiba, Sachiko Ogasawara, Osamu Nakashima, Yoshiki Naito, Hironori Kusano, Yutaro Mihara, Masahiko Tanigawa, Hirohisa Yano
Pages: 1458-1466
Published online on: 07 June 2019

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Article

Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC‑SD gallbladder carcinoma cells

Huiping Chen, Xiujuan Wu, Yitao Duan, Dexian Zhi, Min Zou, Zhihong Zhao, Xiaojun Zhang, Xiaoang Yang, Jianying Zhang
Pages: 1467-1474
Published online on: 27 May 2019

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Article

MicroRNA‑432 is downregulated in cervical cancer and directly targets FN1 to inhibit cell proliferation and invasion

Shanzong Wang, Baohong Gao, Hailin Yang, Xuejian Liu, Xia Wu, Weijuan Wang
Pages: 1475-1482
Published online on: 27 May 2019

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Article Open Access

Low expression of miR‑125a‑5p is associated with poor prognosis in patients with gastric cancer

Guan Li, Sheng Ao, Jianing Hou, Guoqing Lyu
Pages: 1483-1490
Published online on: 31 May 2019

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Article Open Access

Cervical carcinoma high‑expressed long non‑coding RNA 1 may promote growth of colon adenocarcinoma through interleukin‑17A

Jue Wang, Hui Li, Cuiying Zhang, Liying Xue, Zhihui Cai
Pages: 1491-1496
Published online on: 31 May 2019

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Article Open Access

Expression of the immune checkpoint receptor TIGIT in seminoma

Andrea Hinsch, Niclas C. Blessin, Ronald Simon, Martina Kluth, Kristine Fischer, Claudia Hube‑Magg, Wenchao Li, Georgia Makrypidi‑Fraune, Björn Wellge, Tim Mandelkow, Nicolaus F. Debatin, Doris Höflmayer, Maximilian Lennartz, Guido Sauter, Jakob R. Izbicki, Sarah Minner, Franziska Büscheck, Ria Uhlig, David Dum, Till Krech, Andreas M. Luebke, Corinna Wittmer, Frank Jacobsen, Eike Burandt, Stefan Steurer, Waldemar Wilczak
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Overexpression of carbonyl reductase 1 inhibits malignant behaviors and epithelial mesenchymal transition by suppressing TGF‑β signaling in uterine leiomyosarcoma cells

Takuya Kajimura, Shun Sato, Akihiro Murakami, Maki Hayashi‑Okada, Kengo Nakashima, Kotaro Sueoka, Norihiro Sugino
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Published online on: 31 May 2019

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Cisplatin or carboplatin? Neutrophil to lymphocyte ratio may serve as a useful factor in small cell lung cancer therapy selection

Zhangchi Pan, Lu Zhang, Chen Liu, Xiaobing Huang, Songfei Shen, Xiaoyan Lin, Chunmei Shi
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Novel tumor‑suppressor FOXN3 is downregulated in adult acute myeloid leukemia

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Endocannabinoid system and the expression of endogenous ceramides in human hepatocellular carcinoma

Jiayong Yang, Yifeng Tian, Ruihe Zheng, Lei Li, Funan Qiu
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Lentivirus‑mediated RNA interference targeting programmed death receptor ligand 1 increases the immunologic anti‑tumor effect of dendritic cell vaccination against pancreatic cancer in SCID‑hu mice

Jin Wang, Mingbing Sun, Xinguo Zhu, Hua Zhao, Deli Mao, Zhe Zhang, Xin Zhao
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Effect of inhibiting ACAT‑1 expression on the growth and metastasis of Lewis lung carcinoma

Minghong Bi, Xuxu Qiao, Haoran Zhang, Huazhang Wu, Zhenyuan Gao, Hairong Zhou, Mohan Shi, Yaping Wang, Jingru Yang, Jianguo Hu, Weichen Liang, Yonghong Liu, Xujie Qiao, Shanshan Zhang, Zhibiao Zhao
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Corticosterone inhibits the expression of cannabinoid receptor‑1 and cannabinoid receptor agonist‑induced decrease in cell viability in glioblastoma cells

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Significant association of EED promoter hypomethylation with colorectal cancer

Xiuru Ying, Ranran Pan, Jie Zhong, Boyi Wu, Yuting Jiang, Jieer Ying, Cong Zhou, Jie Dai, Shuangying Zhao, Yinan Shen, Wei Zhang, Shiwei Duan
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Shi-Shuai Wen, Ting-Ting Zhang, Di-Xin Xue, Wei-Li Wu, Yu-Long Wang, Yu Wang, Qing-Hai Ji, Yong-Xue Zhu, Ning Qu, Rong-Liang Shi
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Mixed adenoendocrine carcinoma in the extrahepatic biliary tract: A case report and literature review

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Predicting prognosis of endometrioid endometrial adenocarcinoma on the basis of gene expression and clinical features using Random Forest

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MicroRNA‑362‑5p enhances the cisplatin sensitivity of gastric cancer cells by targeting suppressor of zeste 12 protein

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Achieving adequate lymph node dissection in treating esophageal squamous cell carcinomas by radical lymphadenectomy: Beyond the scope of numbers of harvested lymph nodes

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Pterostilbene inhibits lung squamous cell carcinoma growth in vitro and in vivo by inducing S phase arrest and apoptosis

Kok‑Tong Tan, Ping‑Wen Chen, Shiming Li, Te‑Min Ke, Sheng‑Hao Lin, Ching‑Chieh Yang
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Article Open Access

Predictive value of LN metastasis detected by 18F‑FDG PET/CT in patients with papillary thyroid cancer receiving iodine‑131 radiotherapy

Chao Li, Jian Zhang, Hui Wang
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Article Open Access

lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
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Article Open Access

miR‑496, miR‑1185, miR‑654, miR‑3183 and miR‑495 are downregulated in colorectal cancer cells and have putative roles in the mTOR pathway

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Article Open Access

Prognostic value of the mRNA expression of gap junction α members in patients with gastric cancer

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DNA methylation profiling identifies potentially significant epigenetically‑regulated genes in glioblastoma multiforme

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ILF2 promotes anchorage independence through direct regulation of PTEN

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Physicochemical and pathohistological changes in experimental fibrosarcoma tumors of hamsters treated with metformin and itraconazole

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Pages: 1713-1722
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Five genes may predict metastasis in non‑small cell lung cancer using bioinformatics analysis

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Efficacy of interventional therapy and effect on inflammatory factors in patients with gastric cancer after chemotherapy

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Article Open Access

Long non‑coding RNA colon cancer‑associated transcript 2 may promote esophageal cancer growth and metastasis by regulating the Wnt signaling pathway

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Article Open Access

Correlation between PTEN gene polymorphism and oral squamous cell carcinoma

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Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer

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Identification of CFTR as a novel key gene in chromophobe renal cell carcinoma through bioinformatics analysis

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Tumor microenvironment immune types in gastric cancer are associated with mismatch repair however, not HER2 status

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MicroRNA‑758 inhibits cervical cancer cell proliferation and metastasis by targeting HMGB3 through the WNT/β‑catenin signaling pathway

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Rab23 contributes to the progression of colorectal cancer via protein kinase B and extracellular signal‑regulated kinase signaling pathways

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Dosimetric comparison between three‑ and four‑dimensional computerised tomography radiotherapy for breast cancer

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Cervical cancer evaluated with integrated 18F‑FDG PET/MR

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Effect of prophylactic TACE on 5‑year survival of patients with hepatocellular carcinoma after hepatectomy

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Intermittent hypoxia alleviates increased VEGF and pro‑angiogenic potential in liver cancer cells

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Tumor‑associated macrophages affect the biological behavior of lung adenocarcinoma A549 cells through the PI3K/AKT signaling pathway

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Ecotropic virus integration‑1 and calreticulin as novel prognostic markers in triple‑negative breast cancer: A retrospective cohort study

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Association between microRNA‑125b expression in formalin‑fixed paraffin‑embedded tumor tissues and prognosis in patients with melanoma

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Clinicopathological characteristics and survival of primary malignant melanoma of the esophagus

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Article Open Access

CDS‑1548 induces apoptosis in HeLa cells by activating caspase 3

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SHCBP1 regulates apoptosis in lung cancer cells through phosphatase and tensin homolog

Fei Wang, Yi Li, Zhe Zhang, Jingxin Wang, Jinghao Wang
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Molecular profiling of transcription factors pinpoints MYC‑estrogen related receptor α‑regulatory factor X5 panel for characterizing the immune microenvironment and predicting the efficacy of immune checkpoint inhibitors in renal cell carcinoma

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Chaetocin induces caspase‑dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species

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MicroRNA‑181 inhibits glioblastoma cell growth by directly targeting CCL8

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Stimulated upregulation of HO‑1 is associated with inadequate response of gastric and ovarian cancer cell lines to hyperthermia and cisplatin treatment

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Downregulation of BAG3 attenuates cisplatin resistance by inhibiting autophagy in human epithelial ovarian cancer cells

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Integrated miRNA profiling and bioinformatics analyses reveal upregulated miRNAs in gastric cancer

Chen Yuan, Yue Zhang, Wenwen Tu, Yusheng Guo
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Oxaliplatin reverses the GLP‑1R‑mediated promotion of intrahepatic cholangiocarcinoma by altering FoxO1 signaling

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Case Report

Pathological diagnosis and treatment outcome of gastric metastases from small cell lung cancer: A case report

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Downregulation of lncRNA AWPPH inhibits colon cancer cell proliferation by downregulating GLUT‑1

Jie Bai, Jian Xu, Jian Zhao, Rui Zhang
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MicroRNA expression profiling in the colorectal normal‑adenoma‑carcinoma transition

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Article

Anti‑EpCAM antibodies for detection of metastatic carcinoma in effusions and peritoneal wash

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Article

Ascites do not affect the rate of complete cytoreductive surgery and prognosis in patients with primary ovarian cancer with ascites treated with hyperthermic intraperitoneal chemotherapy

Mingchen Ba, Hui Long, Xiangliang Zhang, Zhaofei Yan, Shuai Wang, Yinbing Wu, Yuanfeng Gong, Shuzhong Cui
Pages: 2025-2033
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Article

MicroRNA‑144 targets APP to regulate AML1/ETO+ leukemia cell migration via the p‑ERK/c‑Myc/MMP‑2 pathway

Ling Jiang, Wei Meng, Guopan Yu, Changxin Yin, Zhixiang Wang, Libin Liao, Fanyi Meng
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Article

MicroRNA‑2053 overexpression inhibits the development and progression of hepatocellular carcinoma

Tao Song, Ke Ma, Cui Zhao, Jijin Yang, Jingyu Liu
Pages: 2043-2049
Published online on: 20 June 2019

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Article

Long non‑coding RNA bladder cancer‑associated transcript 2 contributes to disease progression, chemoresistance and poor survival of patients with colorectal cancer

Yongjun Ren, Caixia Zhao, Yi He, Hao Xu, Xuli Min
Pages: 2050-2058
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Article

Prognostic value of multiple epithelial mesenchymal transition‑associated proteins in intrahepatic cholangiocarcinoma

Xiangguo Tian, Zhixin Cao, Qian Ding, Zhen Li, Chunqing Zhang
Pages: 2059-2065
Published online on: 24 June 2019

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Article

MicroRNA‑381 suppresses proliferation and invasion of prostate cancer cells through downregulation of the androgen receptor

Xin Rui, Ting‑Ting Gu, Hua‑Feng Pan, Si‑Liang Shao, Hong‑Xiang Shao
Pages: 2066-2072
Published online on: 12 June 2019

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Overexpression of LIMD2 promotes the progression of non‑small cell lung cancer

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Article

Diagnostic and prognostic factors for patients with primary pulmonary non‑Hodgkin's lymphoma: A 16‑year single‑center retrospective study

Jiang Qian, Dong‑Lan Luo, Jin‑E Zhang, Wen‑Yu Li, Xing‑Lin Gao, Xiang‑Feng Fang, Hong An, Jun‑Liang Deng, Qiong Li, Jian Wu
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Article

Response prediction to oxaliplatin plus 5‑fluorouracil chemotherapy in patients with colorectal cancer using a four‑protein immunohistochemical model

Junjie Gu, Zhe Li, Jianfeng Zhou, Zhao Sun, Chunmei Bai
Pages: 2091-2101
Published online on: 14 June 2019

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Article

Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Josephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Pages: 2102-2108
Published online on: 21 June 2019

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Article

Long non‑coding RNA NKILA serves as a biomarker in the early diagnosis and prognosis of patients with colorectal cancer

Peng Jiang, Xiaoting Han, Yingnan Zheng, Jianchao Sui, Weiping Bi
Pages: 2109-2117
Published online on: 24 June 2019

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Article

Maximum allele frequency observed in plasma: A potential indicator of liquid biopsy sensitivity

Yong Tang, Xianling Liu, Zhu'an Ou, Zhe He, Qihang Zhu, Ye Wang, Mei Yang, Junyi Ye, Han Han‑Zhang, Guibin Qiao
Pages: 2118-2124
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Decision tree‑based classifiers for lung cancer diagnosis and subtyping using TCGA miRNA expression data

Masih Sherafatian, Fateme Arjmand
Pages: 2125-2131
Published online on: 10 June 2019

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Article

Curcumin enhances cisplatin sensitivity by suppressing NADPH oxidase 5 expression in human epithelial cancer

Siqi Chen, Wei Gao, Min‑Juan Zhang, Jimmy Yu‑Wai Chan, Thian‑Sze Wong
Pages: 2132-2139
Published online on: 14 June 2019

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Article

Clinical features of immune‑related thyroid dysfunction and its association with outcomes in patients with advanced malignancies treated by PD‑1 blockade

Tomoki Sakakida, Takeshi Ishikawa, Junji Uchino, Yusuke Chihara, Satoshi Komori, Jun Asai, Tsukasa Narukawa, Akihito Arai, Tsutomu Kobayashi, Hiroaki Tsunezuka, Toshiyuki Kosuga, Hirotaka Konishi, Fumiya Hongo, Masayoshi Inoue, Shigeru Hirano, Osamu Ukimura, Yoshito Itoh, Tetsuya Taguchi, Koichi Takayama
Pages: 2140-2147
Published online on: 12 June 2019

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Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
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Article Open Access

Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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Article Open Access

NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Article Open Access

Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Article Open Access

Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Review Open Access

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Article Open Access

Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Article Open Access

Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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