|
1
|
Siegel RL, Miller KD and Ahmedin J: Cancer
statistics, 2018. CA Cancer J Clin. 68:7–30. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Babon JJ, Varghese LN and Nicola NA:
Inhibition of IL-6 family cytokines by SOCS3. Semin Immunol.
26:13–19. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Liau N, Laktyushin A, Lucet IS, Murphy JM,
Yao S, Whitlock E, Callaghan K, Nicola NA, Kershaw NJ and Babon JJ:
The molecular basis of JAK/STAT inhibition by SOCS1. Nat Commun.
9:15582018. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Liang YB, Tang H, Chen ZB, Zeng LJ, Wu JG,
Yang W, Li ZY and Ma ZF: Downregulated SOCS1 expression activates
the JAK1/STAT1 pathway and promotes polarization of macrophages
into M1 type. Mol Med Rep. 16:6405–6411. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Chan SR, Rickert CG, Vermi W, Sheehan KC,
Arthur C, Allen JA, White JM, Archambault J, Lonardi S, Mcdevitt
TM, et al: Dysregulated STAT1-SOCS1 control of JAK2 promotes
mammary luminal progenitor cell survival and drives ERα(+)
tumorigenesis. CDD. 21:234–246. 2014.
|
|
6
|
Wingelhofer B, Neubauer HA, Valent P, Han
X, Constantinescu SN, Gunning PT, Müller M and Moriggl R:
Implications of STAT3 and STAT5 signaling on gene regulation and
chromatin remodeling in hematopoietic cancer. Leukemia.
1:1713–1726. 2018. View Article : Google Scholar
|
|
7
|
Scutti JA, Matsuo AL, Pereira FV, Massaoka
MH, Figueiredo CR, Moreira DF, Belizário JE and Travassos LR: Role
of SOCS1 gene on melanoma cell growth and tumor development. Transl
Oncol. 4:101–109. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Saelee P, Chuensumran U, Wongkham S,
Chariyalertsak S, Tiwawech D and Petmitr S: Hypermethylation of
suppressor of cytokine signaling 1 in hepatocellular carcinoma
patients. Asian Pac J Cancer Prev. 13:3489–3493. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zalewski K, Doniec J, Włodzimierz W and
Bidziński M: Revised FIGO staging systems for gynecologic
malignancies-2009 update. Ginekol Pol. 81:778–782. 2010.(In
Polish). PubMed/NCBI
|
|
10
|
Li LC and Dahiya R: MethPrimer: Designing
primers for methylation PCRs. Bioinformatics. 18:1427–1431. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Li C, Yang W, Zhang J, Zheng X, Yao Y, Tu
K and Liu Q: SREBP-1 has a prognostic role and contributes to
invasion and metastasis in human hepatocellular carcinoma. Int J
Mol Sci. 15:7124–7138. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Therneau T: Survival: Survival analysis
including penalised likelihood. https://CRAN.R-project.org/package=survivalOctober
2–2018
|
|
14
|
R Core Team: R, . A Language and
Environment for Statistical Computing. R Foundation for Statistical
Computing; Vienna, Austria: http://www.R-project.orgOctober 2–2018
|
|
15
|
Chim CS, Fung TK, Cheung WC, Liang R and
Kwong YL: SOCS1 and SHP1 hypermethylation in multiple myeloma:
Implications for epigenetic activation of the Jak/STAT pathway.
Blood. 103:4630–4635. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Endo TA, Masuhara M, Yokouchi M, Suzuki R,
Sakamoto H, Mitsui K, Matsumoto A, Tanimura S, Ohtsubo M, Misawa H,
et al: A new protein containing an SH2 domain that inhibits JAK
kinases. Nature. 387:921–924. 1997. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yasukawa H, Misawa H, Sakamoto H, Masuhara
M, Sasaki A, Wakioka T, Ohtsuka S, Imaizumi T, Matsuda T, Ihle JN
and Yoshimura A: The JAK-binding protein JAB inhibits Janus
tyrosine kinase activity through binding in the activation loop.
EMBO J. 18:1309–1320. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Babon JJ, Kershaw NJ, Murphy JM, Varghese
LN, Laktyushin A, Young SN, Lucet IS, Norton RS and Nicola NA:
Suppression of cytokine signaling by SOCS3: Characterization of the
mode of inhibition and the basis of its specificity. Immunity.
36:239–250. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kazi JU, Kabir NN, Flores-Morales A and
Rönnstrand L: SOCS proteins in regulation of receptor tyrosine
kinase signaling. CMLS. 71:3297–3310. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Shimada K, Serada S, Fujimoto M, Nomura S,
Nakatsuka R, Harada E, Iwahori K, Tachibana I, Takahashi T,
Kumanogoh A, et al: Molecular mechanism underlying the
antiproliferative effect of suppressor of cytokine signaling-1 in
non-small-cell lung cancer cells. Cancer Sci. 104:1483–1491. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kamizono S, Hanada T, Yasukawa H,
Minoguchi S, Kato R, Minoguchi M, Hattori K, Hatakeyama S, Yada M,
Morita S, et al: The SOCS box of SOCS1 accelerates
ubiquitin-dependent proteolysis of TEL-JAK2. J Biol Chem.
276:12530–12538. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yoshikawa H, Matsubara K, Qian GS, Jackson
P, Groopman JD, Manning JE, Harris CC and Herman JG: SOCS1, a
negative regulator of the JAK/STAT pathway, is silenced by
methylation in human hepatocellular carcinoma and shows
growth-suppression activity. Nat Genet. 28:29–35. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Galm O, Yoshikawa H, Esteller M, Osieka R
and Herman JG: SOCS1, a negative regulator of cytokine signaling,
is frequently silenced by methylation in multiple myeloma. Blood.
101:2784–2788. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lin YC, Lin CK, Tsai YH, Weng HH, Li YC,
You L, Chen JK, Jablons DM and Yang CT: Adenovirus-mediated SOCS3
gene transfer inhibits the growth and enhances the radiosensitivity
of human non-small cell lung cancer cells. Oncol Rep. 24:1605–1612.
2010.PubMed/NCBI
|
|
25
|
Watanabe D, Ezoe S, Fujimoto M, Kimura A,
Saito Y, Nagai H, Tachibana I, Matsumura I, Tanaka T, Kanegane H,
et al: Suppressor of cytokine signalling-1 gene silencing in acute
myeloid leukaemia and human haematopoietic cell lines. Br J
Haematol. 126:726–735. 2015. View Article : Google Scholar
|
|
26
|
Sutherland KD, Lindeman GJ, Choong DY,
Wittlin S, Brentzell L, Phillips W, Campbell IG and Visvader JE:
Differential hypermethylation of SOCS genes in ovarian and breast
carcinomas. Oncogene. 23:7726–7733. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Burke WM, Jin X, Lin HJ, Huang M, Liu R,
Reynolds RK and Lin J: Inhibition of constitutively active Stat3
suppresses growth of human ovarian and breast cancer cells.
Oncogene. 20:7925–7934. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Sasi W, Jiang WG, Sharma A and Mokbel K:
Higher expression levels of SOCS 1,3,4,7 are associated with
earlier tumour stage and better clinical outcome in human breast
cancer. BMC Cancer. 10:1782010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Flowers LO, Subramaniam PS and Johnson HM:
A SOCS1 peptide mimetic inhibits both constitutive and IL-6 induced
activation of STAT3 in prostate cancer cells. Oncogene.
24:2114–2120. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Griffiths EA, Gore SD, Hooker CM, Mohammad
HP, Mcdevitt MA, Smith BD, Karp JE, Herman JG and Carraway HE:
Epigenetic differences in cytogenetically normal versus abnormal
acute myeloid leukemia. Epigenetics. 5:590–600. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Li Z, Metze D, Nashan D, Müller-Tidow C,
Serve HL, Poremba C, Luger TA and Böhm M: Expression of SOCS1,
suppressor of cytokine signalling-1, in Human Melanoma. J Invest
Dermatol. 123:737–745. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Nagai H, Kim YS, Konishi N, Baba M, Kubota
T, Yoshimura A and Emi M: Combined hypermethylation and chromosome
loss associated with inactivation of SSI-1/SOCS1/JAB gene in human
hepatocellular carcinomas. Cancer Lett. 186:59–65. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yun UJ, Park SE, Jo YS, Kim J and Shin DY:
DNA damage induces the IL-6/STAT3 signaling pathway, which has
anti-senescence and growth-promoting functions in human tumors.
Cancer Lett. 323:155–166. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Cokic VP, Bhattacharya B, Beleslin-Cokic
BB, Noguchi CT, Puri RK and Schechter AN: Jak-STAT and AKT
pathway-coupled genes in erythroid progenitor cells through
ontogeny. J Transl Med. 10:1162012. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Haricharan S and Li Y: STAT signaling in
mammary gland differentiation, cell survival and tumorigenesis. Mol
Cell Endocrinol. 382:560–569. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Dallavalle C, Albino D, Civenni G, Merulla
J, Ostano P, Mellogrand M, Rossi S, Losa M, D'Ambrosio G, Sessa F,
et al: MicroRNA-424 impairs ubiquitination to activate STAT3 and
promote prostate tumor progression. JCI. 126:4585–4602. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhang X, Ren D, Wu X, Lin X, Ye L, Lin C,
Wu S, Zhu J, Peng X and Song L: miR-1266 contributes to pancreatic
cancer progression and chemoresistance by STAT3 and NF-κB signaling
pathways. Mol Ther Nucleic Acids. 11:142–158. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Saydmohammed M, Joseph D and Syed V:
Curcumin suppresses constitutive activation of STAT-3 by
up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in
ovarian and endometrial cancer cells. J Cell Biochem. 110:447–456.
2010.PubMed/NCBI
|
|
39
|
Cai L, Zhang G, Tong X, You Q, An Y, Wang
Y, Guo L, Wang T, Zhu D and Zheng J: Growth inhibition of human
ovarian cancer cells by blocking STAT3 activation with small
interfering RNA. Eur J Obstet Gynecol Reprod Biol. 148:73–80. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Nakagawa S, Serada S, Kakubari R,
Hiramatsu K, Sugase T, Matsuzaki S, Matsuzaki S, Ueda Y, Yoshino K,
Ohkawara T, et al: Intratumoral delivery of an adenoviral vector
carrying the SOCS1 gene enhances T cell-mediated anti-tumor
immunity by suppressing PD-L1. Mol Cancer Ther. 17:1941–1950. 2018.
View Article : Google Scholar : PubMed/NCBI
|
