Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
August-2019 Volume 18 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
August-2019 Volume 18 Issue 2

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer

  • Authors:
    • Qingxiang Cao
    • Xiaopeng Tian
    • Chuanzhen Dong
    • Huimin Bu
    • Yi Cheng
  • View Affiliations / Copyright

    Affiliations: Department of Anaesthesia, Dongying People's Hospital, Dongying, Shandong 257000, P.R. China
  • Pages: 1761-1766
    |
    Published online on: June 20, 2019
       https://doi.org/10.3892/ol.2019.10503
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The effects of different doses of cisatracurium besilate on perioperative hemodynamics and early postoperative cognitive function in patients undergoing radical resection of lung cancer were investigated. One hundred and thirty-six patients who underwent radical resection of lung cancer from June 2013 to June 2016 in Dongying People's Hospital were retrospectively analyzed. Patients who were not given atracurium were selected as the control group (n=35). According to the different anesthetic doses, patients in the experimental group were separated into low dose (0.15 mg/kg cisatracurium besilate) group (LD group, n=34), medium dose (0.2 mg/kg cisatracurium besilate) group (MD group, n=36) and high dose (0.3 mg/kg cisatracurium besilate) group (HD group, n=31). The mean arterial pressure and heart rate (HR) were recorded before induction of anesthesia (T0), at the time of entering pleural cavity (T1), at the end of surgery (T2), and 1 day after surgery (T3). The Mini-Mental State Examination (MMSE) was used to evaluate the postoperative cognitive function scores of the 4 groups 1 day before operation and on the 1st, 3rd and 7th day after surgery. The agitation of patients at 6 and 12 h after operation was evaluated by Ramsay sedation score. There was no significant difference in arterial pressure among the four groups at T2 and T3 (P>0.05). There was no significant difference in terms of MMSE among the four groups 1 day before operation, 3 days after operation and 7 days after operation, but the MMSE score of the control group was significantly lower than that of the LD, MD and HD groups 1 day after surgery (P<0.05). Therefore, cisatracurium besilate can stabilize hemodynamics during radical operation of lung cancer and reduce the incidence of postoperative cognitive dysfunction, and it has no close association with the dose.
View Figures
View References

1 

Reck M, Rodríguez-Abreu D, Robinson AG, Hui R, Csőszi T, Fülöp A, Gottfried M, Peled N, Tafreshi A, Cuffe S, et al KEYNOTE-024 Investigators, : Pembrolizumab versus chemotherapy for PD-L1-positive non-small-cell lung cancer. N Engl J Med. 375:1823–1833. 2016. View Article : Google Scholar : PubMed/NCBI

2 

Zhang Y, Sui J, Shen X, Li C, Yao W, Hong W, Peng H, Pu Y, Yin L and Liang G: Differential expression profiles of microRNAs as potential biomarkers for the early diagnosis of lung cancer. Oncol Rep. 37:3543–3553. 2017. View Article : Google Scholar : PubMed/NCBI

3 

Deng Y, Hao Z and Fu X: Development, application details, and prospects of Uni-VATS on lung cancer radical operation under the concept of ‘precise medical treatment’. Zhongguo Fei Ai Za Zhi. 19:371–376. 2016.(In Chinese). PubMed/NCBI

4 

Zheng Y and Bueno R: Commercially available prognostic molecular models in early-stage lung cancer: A review of the Pervenio Lung RS and Myriad myPlan Lung Cancer tests. Expert Rev Mol Diagn. 15:589–596. 2015. View Article : Google Scholar : PubMed/NCBI

5 

Shen L, Luo Y, Lu Z, Hu X, Ding W and Yu B: Cost-effectiveness of different regimens of anesthesia for day surgery in China. Int J Clin Exp Med. 7:5744–5750. 2014.PubMed/NCBI

6 

Jia ZM, Hao HN, Huang ML, Ma DF, Jia XL and Ma B: Influence of dexmedetomidine to cognitive function during recovery period for children with general anesthesia. Eur Rev Med Pharmacol Sci. 21:1106–1111. 2017.PubMed/NCBI

7 

Tufail M, Hussain M, Russell R, Nasimudeen A, Martin N and Panchal R: Success rate of local anaesthetic video assisted thoracoscopy (LAVAT) talc poudrage for malignant pleural effusions at a UK tertiary centre. Lung Cancer. 87 (Suppl 1):S202015. View Article : Google Scholar

8 

Gunatilake S, Parker L, Bishop L, Babu S, Clark R and Chauhan A: Operator sensitivity for pleural malignancy at medical thoracoscopy. Lung Cancer. 87 (Suppl 1):S18–S19. 2015. View Article : Google Scholar

9 

Rahimzadeh P, Faiz SHR, Alebouyeh MR, Dasian A and Sayarifard A: Appropriate anesthesia regimen to control sevoflurane-induced emergence agitation in children; propofol-lidocaine and thiopental sodium-lidocaine: A randomized controlled trial. Iran Red Crescent Med J. 16:e163882014. View Article : Google Scholar : PubMed/NCBI

10 

Movafegh A, Amini S, Sharifnia H, Torkamandi H, Hayatshahi A and Javadi M: Cost analysis and safety comparison of cisatracurium and atracurium in patients undergoing general anesthesia. Eur Rev Med Pharmacol Sci. 17:447–450. 2013.PubMed/NCBI

11 

Grosse-Sundrup M, Henneman JP, Sandberg WS, Bateman BT, Uribe JV, Nguyen NT, Ehrenfeld JM, Martinez EA, Kurth T and Eikermann M: Intermediate acting non-depolarizing neuromuscular blocking agents and risk of postoperative respiratory complications: Prospective propensity score matched cohort study. BMJ. 345:e63292012. View Article : Google Scholar : PubMed/NCBI

12 

Cope TM and Hunter JM: Selecting neuromuscular-blocking drugs for elderly patients. Drugs Aging. 20:125–140. 2003. View Article : Google Scholar : PubMed/NCBI

13 

Ghodraty MR, Saif AA, Kholdebarin AR, Rokhtabnak F, Pournajafian AR, Nikzad-Jamnani AR, Shah A and Nader ND: The effects of magnesium sulfate on neuromuscular blockade by cisatracurium during induction of anesthesia. J Anesth. 26:858–863. 2012. View Article : Google Scholar : PubMed/NCBI

14 

Sharrock NE: Epidural anesthetic dose responses in patients 20 to 80 years old. Anesthesiology. 49:425–428. 1978. View Article : Google Scholar : PubMed/NCBI

15 

Yang XH, Bai Q, Lv MM, Fu HG, Dong TL and Zhou Z: Effect of dexmedetomidine on immune function of patients undergoing radical mastectomy: A double blind and placebo control study. Eur Rev Med Pharmacol Sci. 21:1112–1116. 2017.PubMed/NCBI

16 

Ramsay MA, Savege TM, Simpson BR and Goodwin R: Controlled sedation with alphaxalone-alphadolone. BMJ. 2:656–659. 1974. View Article : Google Scholar : PubMed/NCBI

17 

Zappa C and Mousa SA: Non-small cell lung cancer: Current treatment and future advances. Transl Lung Cancer Res. 5:288–300. 2016. View Article : Google Scholar : PubMed/NCBI

18 

Esteve N, Ferrer A, Sansaloni C, Mariscal M, Torres M and Mora C: Epidural anesthesia and analgesia in liver resection: Safety and effectiveness. Rev Esp Anestesiol Reanim. 64:86–94. 2017.(In Spanish). View Article : Google Scholar : PubMed/NCBI

19 

Soni P: Comparative study for better adjuvant with ropivacaine in epidural anesthesia. Anesth Essays Res. 10:218–222. 2016. View Article : Google Scholar : PubMed/NCBI

20 

Mroziński P, Lango R, Biedrzycka A, Kowalik MM, Pawlaczyk R and Rogowski J: Comparison of haemodynamics and myocardial injury markers under desflurane vs. propofol anaesthesia for off-pump coronary surgery. A prospective randomised trial. Anaesthesiol Intensive Ther. 46:4–13. 2014. View Article : Google Scholar : PubMed/NCBI

21 

Gharedaghi MH, Rahimian R, Dehpour AR, Yousefzadeh-Fard Y and Mohammadi-Farani A: Dinitrobenzene sulphonic acid-induced colitis impairs spatial recognition memory in mice: Roles of N-methyl D-aspartate receptors and nitric oxide. Psychopharmacology (Berl). 232:3081–3090. 2015. View Article : Google Scholar : PubMed/NCBI

22 

Yu DJ and Gao HY: Influences of cisatracurium besylate and vecuronium bromide on muscle relaxant effects and electromyography of tracheal intubation under general anesthesia. Eur Rev Med Pharmacol Sci. 21:1974–1979. 2017.PubMed/NCBI

23 

Minton MD, Stirt JA, Bedford RF and Haworth C: Intracranial pressure after atracurium in neurosurgical patients. Anesth Analg. 64:1113–1116. 1985. View Article : Google Scholar : PubMed/NCBI

24 

Voss J, Riedel T, Sommer M and Rosolski T: Cis-atracurium - an equivalent substitution for atracurium in pediatric anesthesia? Anaesthesiol Reanim. 27:93–97. 2002.(In German). PubMed/NCBI

25 

Sator-Katzenschlager SM, Oehmke MJ, Kontaratos M, Wedrich A, Heinze G and Weinstabl C: Effect of different doses of cisatracurium on intraocular pressure in sedated patients. Eur J Anaesthesiol. 19:823–828. 2002. View Article : Google Scholar : PubMed/NCBI

26 

Yu H, Yang XY and Liu B: EMLA Cream coated on the rigid bronchoscope for tracheobronchial foreign body removal in children. Laryngoscope. 119:158–161. 2009. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Cao Q, Tian X, Dong C, Bu H and Cheng Y: Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer. Oncol Lett 18: 1761-1766, 2019.
APA
Cao, Q., Tian, X., Dong, C., Bu, H., & Cheng, Y. (2019). Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer. Oncology Letters, 18, 1761-1766. https://doi.org/10.3892/ol.2019.10503
MLA
Cao, Q., Tian, X., Dong, C., Bu, H., Cheng, Y."Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer". Oncology Letters 18.2 (2019): 1761-1766.
Chicago
Cao, Q., Tian, X., Dong, C., Bu, H., Cheng, Y."Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer". Oncology Letters 18, no. 2 (2019): 1761-1766. https://doi.org/10.3892/ol.2019.10503
Copy and paste a formatted citation
x
Spandidos Publications style
Cao Q, Tian X, Dong C, Bu H and Cheng Y: Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer. Oncol Lett 18: 1761-1766, 2019.
APA
Cao, Q., Tian, X., Dong, C., Bu, H., & Cheng, Y. (2019). Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer. Oncology Letters, 18, 1761-1766. https://doi.org/10.3892/ol.2019.10503
MLA
Cao, Q., Tian, X., Dong, C., Bu, H., Cheng, Y."Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer". Oncology Letters 18.2 (2019): 1761-1766.
Chicago
Cao, Q., Tian, X., Dong, C., Bu, H., Cheng, Y."Effects of different doses of cisatracurium besilate on hemodynamics and postoperative cognitive function in patients undergoing radical resection of lung cancer". Oncology Letters 18, no. 2 (2019): 1761-1766. https://doi.org/10.3892/ol.2019.10503
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team