|
1
|
Cao G, Li HB, Yin Z and Flavell RA: Recent
advances in dynamic m6A RNA modification. Open Biol. 6:1600032016.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Wang X, Lu Z, Gomez A, Hon GC, Yue Y, Han
D, Fu Y, Parisien M, Dai Q, Jia G, et al:
N6-methyladenosine-dependent regulation of messenger RNA stability.
Nature. 505:117–120. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wang X, Zhao BS, Roundtree IA, Lu Z, Han
D, Ma H, Weng X, Chen K, Shi H and He C: N(6)-methyladenosine
modulates messenger RNA translation efficiency. Cell.
161:1388–1399. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Batista PJ, Molinie B, Wang J, Qu K, Zhang
J, Li L, Bouley DM, Lujan E, Haddad B, Daneshvar K, et al: m(6)A
RNA modification controls cell fate transition in mammalian
embryonic stem cells. Cell Stem Cell. 15:707–719. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Meyer KD, Patil DP, Zhou J, Zinoviev A,
Skabkin MA, Elemento O, Pestova TV, Qian SB and Jaffrey SR: 5′UTR
m(6)A promotes cap-independent translation. Cell. 163:999–1010.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Zheng G, Dahl JA, Niu Y, Fedorcsak P,
Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, et al: ALKBH5
is a mammalian RNA Demethylase that impacts RNA metabolism and
mouse fertility. Mol Cell. 49:18–29. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Xiao W, Adhikari S, Dahal U, Chen YS, Hao
YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, et al: Nuclear m(6)A
reader YTHDC1 regulates mRNA splicing. Mol Cell. 61:507–519. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Xiang Y, Laurent B, Hsu CH, Nachtergaele
S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, et al: RNA
m6A methylation regulates the ultraviolet-induced DNA
damage response. Nature. 543:573–576. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lence T, Akhtar J, Bayer M, Schmid K,
Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M and
Roignant JY: m6A modulates neuronal functions and sex
determination in Drosophila. Nature. 540:242–247. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Fu Y, Dominissini D, Rechavi G and He C:
Gene expression regulation mediated through reversible
m6A RNA methylation. Nat Rev Genet. 15:293–306. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ping XL, Sun BF, Wang L, Xiao W, Yang X,
Wang WJ, Adhikari S, Shi Y, Lv Y, Chen YS, et al: Mammalian WTAP is
a regulatory subunit of the RNA N6-methyladenosine
methyltransferase. Cell Res. 24:177–189. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang
L, Jia G, Yu M, Lu Z, Deng X, et al: A METTL3-METTL14 complex
mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem
Biol. 10:93–95. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang
Y, Yi C, Lindahl T, Pan T, Yang YG and He C: N6-methyladenosine in
nuclear RNA is a major substrate of the obesity-associated FTO. Nat
Chem Biol. 7:885–887. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhao X, Yang Y, Sun BF, Shi Y, Yang X,
Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, et al: FTO-dependent
demethylation of N6-methyladenosine regulates mRNA splicing and is
required for adipogenesis. Cell Res. 24:1403–1419. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Han Z, Niu T, Chang J, Lei X, Zhao M, Wang
Q, Cheng W, Wang J, Feng Y and Chai J: Crystal structure of the FTO
protein reveals basis for its substrate specificity. Nature.
464:1205–1209. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Dominissini D, Moshitch-Moshkovitz S,
Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K,
Jacob-Hirsch J, Amariglio N, Kupiec M, et al: Topology of the human
and mouse m6A RNA methylomes revealed by m6A-seq. Nature.
485:201–206. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Xu C, Wang X, Liu K, Roundtree IA, Tempel
W, Li Y, Lu Z, He C and Min J: Structural basis for selective
binding of m6A RNA by the YTHDC1 YTH domain. Nat Chem Biol.
10:927–929. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang S, Zhao BS, Zhou A, Lin K, Zheng S,
Lu Z, Chen Y, Sulman EP, Xie K, Bögler O, et al: m6A Demethylase
ALKBH5 maintains Tumorigenicity of Glioblastoma Stem-like cells by
sustaining FOXM1 expression and cell proliferation program. Cancer
Cell. 31:591–606.e6. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, Sun
G, Lu Z, Huang Y, Yang CG, et al: m6A RNA methylation
regulates the Self-renewal and tumorigenesis of glioblastoma stem
cells. Cell Rep. 18:2622–2634. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Vu LP, Pickering BF, Cheng Y, Zaccara S,
Nguyen D, Minuesa G, Chou T, Chow A, Saletore Y, MacKay M, et al:
The N6-methyladenosine (m6A)-forming enzyme
METTL3 controls myeloid differentiation of normal hematopoietic and
leukemia cells. Nat Med. 23:1369–1376. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Taketo K, Konno M, Asai A, Koseki J,
Toratani M, Satoh T, Doki Y, Mori M, Ishii H and Ogawa K: The
epitranscriptome m6A writer METTL3 promotes chemo- and
radioresistance in pancreatic cancer cells. Int J Oncol.
52:621–629. 2018.PubMed/NCBI
|
|
22
|
Lin S, Choe J, Du P, Triboulet R and
Gregory RI: The m(6)A Methyltransferase METTL3 promotes translation
in human cancer cells. Mol Cell. 62:335–345. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Schwartz S, Mumbach MR, Jovanovic M, Wang
T, Maciag K, Bushkin GG, Mertins P, Ter-Ovanesyan D, Habib N,
Cacchiarelli D, et al: Perturbation of m6A writers reveals two
distinct classes of mRNA methylation at internal and 5′sites. Cell
Rep. 8:284–296. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Yue Y, Liu J, Cui X, Cao J, Luo G, Zhang
Z, Cheng T, Gao M, Shu X, Ma H, et al: VIRMA mediates preferential
m6A mRNA methylation in 3′UTR and near stop codon and
associates with alternative polyadenylation. Cell Discov. 4:102018.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Horiuchi K, Kawamura T, Iwanari H, Ohashi
R, Naito M, Kodama T and Hamakubo T: Identification of Wilms' tumor
1-associating protein complex and its role in alternative splicing
and the cell cycle. J Biol Chem. 288:33292–33302. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ruzicka K, Zhang M, Campilho A, Bodi Z,
Kashif M, Saleh M, Eeckhout D, El-Showk S, Li H, Zhong S, et al:
Identification of factors required for m6A mRNA
methylation in Arabidopsis reveals a role for the conserved E3
ubiquitin ligase HAKAI. New Phytol. 215:157–172. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Li Z, Weng H, Su R, Weng X, Zuo Z, Li C,
Huang H, Nachtergaele S, Dong L, Hu C, et al: FTO plays an
oncogenic role in acute myeloid leukemia as a
N6-methyladenosine RNA Demethylase. Cancer Cell.
31:127–141. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Liu J, Ren D, Du Z, Wang H, Zhang H and
Jin Y: m6A demethylase FTO facilitates tumor progression
in lung squamous cell carcinoma by regulating MZF1 expression.
Biochem Biophys Res Commun. 502:456–464. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Yang Z, Li J, Feng G, Gao S, Wang Y, Zhang
S, Liu Y, Ye L, Li Y and Zhang X: MicroRNA-145 modulates
N6-methyladenosine levels by targeting the
3′-untranslated mRNA region of the N6-methyladenosine
binding YTH domain family 2 protein. J Biol Chem. 292:3614–3623.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zhao X, Chen Y, Mao Q, Jiang X, Jiang W,
Chen J, Xu W, Zhong L and Sun X: Overexpression of YTHDF1 is
associated with poor prognosis in patients with hepatocellular
carcinoma. Cancer Biomark. 21:859–868. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu
PJ, Liu C and He C: YTHDF3 facilitates translation and decay of
N6-methyladenosine-modified RNA. Cell Res. 27:315–328.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zhang J, Kong L, Guo S, Bu M, Guo Q, Xiong
Y, Zhu N, Qiu C, Yan X, Chen Q, et al: hnRNPs and ELAVL1 cooperate
with uORFs to inhibit protein translation. Nucleic Acids Res. Oct
26–2016.(Epub ahead of print). View Article : Google Scholar
|
|
33
|
Jares P, Colomer D and Campo E: Genetic
and molecular pathogenesis of mantle cell lymphoma: Perspectives
for new targeted therapeutics. Nat Rev Cancer. 7:750–762. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Leux C, Maynadie M, Troussard X, Cabrera
Q, Herry A, Le Guyader-Peyrou S, Le Gouill S and Monnereau A:
Mantle cell lymphoma epidemiology: A population-based study in
France. Ann Hematol. 93:1327–1333. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Vose JM: Mantle cell lymphoma: 2012 update
on diagnosis, risk-stratification, and clinical management. Am J
Hematol. 87:604–609. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Zhang C, Chen Y, Sun B, Wang L, Yang Y, Ma
D, Lv J, Heng J, Ding Y, Xue Y, et al: m6A modulates
haematopoietic stem and progenitor cell specification. Nature.
549:273–276. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Li HB, Tong J, Zhu S, Batista PJ, Duffy
EE, Zhao J, Bailis W, Cao G, Kroehling L, Chen Y, et al:
m6A mRNA methylation controls T cell homeostasis by
targeting the IL-7/STAT5/SOCS pathways. Nature. 548:338–342. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kwok CT, Marshall AD, Rasko JE and Wong
JJ: Erratum to: Genetic alterations of m6A regulators
predict poorer survival in acute myeloid leukemia. J Hematol Oncol.
10:492017. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Scott DW, Abrisqueta P, Wright GW, Slack
GW, Mottok A, Villa D, Jares P, Rauert-Wunderlich H, Royo C, Clot
G, et al: New molecular assay for the proliferation signature in
mantle cell lymphoma applicable to formalin-fixed paraffin-embedded
biopsies. J Clin Oncol. 35:1668–1677. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Barrett T, Wilhite SE, Ledoux P,
Evangelista C, Kim IF, Tomashevsky M, Marshall KA, Phillippy KH,
Sherman PM, Holko M, et al: NCBI GEO: Archive for functional
genomics data sets-update. Nucleic Acids Res. 41:D991–D995. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Hartmann EM, Campo E, Wright G, Lenz G,
Salaverria I, Jares P, Xiao W, Braziel RM, Rimsza LM, Chan WC, et
al: Pathway discovery in mantle cell lymphoma by integrated
analysis of high-resolution gene expression and copy number
profiling. Blood. 116:953–961. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Hoster E, Dreyling M, Klapper W,
Gisselbrecht C, van Hoof A, Kluin-Nelemans HC, Pfreundschuh M,
Reiser M, Metzner B, Einsele H, et al: A new prognostic index
(MIPI) for patients with advanced-stage mantle cell lymphoma.
Blood. 111:558–565. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Eskelund CW, Dahl C, Hansen JW, Westman M,
Kolstad A, Pedersen LB, Montano-Almendras CP, Husby S, Freiburghaus
C, Ek S, et al: TP53 mutations identify younger mantle cell
lymphoma patients who do not benefit from intensive
chemoimmunotherapy. Blood. 130:1903–1910. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Vose JM: Mantle cell lymphoma: 2017 update
on diagnosis, risk-stratification, and clinical management. Am J
Hematol. 92:806–813. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Ye H, Desai A, Zeng D, Nomie K, Romaguera
J, Ahmed M and Wang ML: Smoldering mantle cell lymphoma. J Exp Clin
Cancer Res. 36:1852017. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Hoster E, Rosenwald A, Berger F, Bernd HW,
Hartmann S, Loddenkemper C, Barth TF, Brousse N, Pileri S,
Rymkiewicz G, et al: Prognostic value of Ki-67 index, cytology, and
growth pattern in mantle-cell lymphoma: Results from randomized
trials of the European mantle cell lymphoma network. J Clin Oncol.
34:1386–1394. 2016. View Article : Google Scholar : PubMed/NCBI
|
