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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2019 Volume 18 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Cervical cancer stem cells and other leading factors associated with cervical cancer development (Review)

Gretel Mendoza‑Almanza, Elizabeth Ortíz‑Sánchez, Leticia Rocha‑Zavaleta, César Rivas‑Santiago, Edgar Esparza‑Ibarra, Jorge Olmos
Pages: 3423-3432
Published online on: 06 August 2019

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Review

Implication of viral microRNAs in the genesis and diagnosis of Epstein‑Barr virus‑associated tumors (Review)

Xiangning Zhang, Yudong Ye, Ming Fu, Biying Zheng, Qianhui Qiu, Zunnan Huang
Pages: 3433-3442
Published online on: 05 August 2019

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Article Open Access

Downregulation of thymopoietin by miR‑139‑5p suppresses cell proliferation and induces cell cycle arrest/apoptosis in pancreatic ductal adenocarcinoma Retraction in /10.3892/ol.2024.14623

Huadong Zhou, Linfei Zhang, Huahua Tu
Pages: 3443-3452
Published online on: 29 July 2019

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Article Open Access

Prognostic roles of mitochondrial transcription termination factors in non‑small cell lung cancer

Shuangyan Sun, Chunjiao Wu, Changliang Yang, Jian Chen, Xiu Wang, Yingji Nan, Zhicheng Huang, Lixia Ma
Pages: 3453-3462
Published online on: 29 July 2019

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Article Open Access

Cross‑disease analysis identified novel common genes for both lung adenocarcinoma and lung squamous cell carcinoma

Guanghui Zhang, Weijie Wang, Weiyang Huang, Xiaoli Xie, Zhigang Liang, Hongbao Cao
Pages: 3463-3470
Published online on: 29 July 2019

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Article Open Access

PLEKHS1: A new molecular marker predicting risk of progression of non‑muscle‑invasive bladder cancer

Géraldine Pignot, Constance Le Goux, Sophie Vacher, Anne Schnitzler, François Radvanyi, Yves Allory, François Lallemand, Nicolas Barry Delongchamps, Marc Zerbib, Benoit Terris, Diane Damotte, Ivan Bieche
Pages: 3471-3480
Published online on: 02 August 2019

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Article Open Access

Association between SFRP promoter hypermethylation and different types of cancer: A systematic review and meta‑analysis

Jun Yu, Yang Xie, Mengying Li, Fenfang Zhou, Zhenyang Zhong, Yuting Liu, Feng Wang, Jian Qi
Pages: 3481-3492
Published online on: 02 August 2019

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Article Open Access

Prognostic nomogram for overall survival in upper aerodigestive tract extranodal natural killer/T‑cell lymphoma, nasal type, stages IE and IIE: A SEER‑based study

Gangjian Wang, Yu Chang, Xiaolong Wu, Xin Li, Ling Li, Mingzhi Zhang
Pages: 3493-3500
Published online on: 06 August 2019

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Article Open Access

Prognostic roles of MAGE family members in breast cancer based on KM‑Plotter Data

Binghan Jia, Xiaoling Zhao, Yao Wang, Jinlong Wang, Yingying Wang, Yuemei Yang
Pages: 3501-3516
Published online on: 06 August 2019

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Article Open Access

Sulfasalazine suppresses thyroid cancer cell proliferation and metastasis through T‑cell originated protein kinase

Ling Zou, Zhi Gao, Fanfan Zeng, Juanjuan Xiao, Junmei Chen, Xiaohong Feng, Di Chen, Ying Fang, Jing Cui, Yang Liu, Zhi Li, Feng Zhu, Qiuhong Duan, Xuan Lin
Pages: 3517-3526
Published online on: 06 August 2019

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Article Open Access

Identifying prognosis and metastasis‑associated genes associated with Ewing sarcoma by weighted gene co‑expression network analysis

Ben Wang, Jie Li, Xin Li, Yunsheng Ou
Pages: 3527-3536
Published online on: 29 July 2019

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Article Open Access

Suberoylanilide hydroxamic acid upregulates histone acetylation and activates endoplasmic reticulum stress to induce apoptosis in HepG2 liver cancer cells

Lei Yu, Rujia Xie, Tian Tian, Lu Zheng, Lei Tang, Shuang Cai, Zihua Ma, Ting Yang, Bing Han, Qin Yang
Pages: 3537-3544
Published online on: 02 August 2019

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Article Open Access

Identification of a 3‑mRNA signature as a novel potential prognostic biomarker in patients with ovarian serous cystadenocarcinoma in G2 and G3

Jiahua Zhou, Yeye Yi, Congjun Wang, Cheng Su, Yige Luo
Pages: 3545-3552
Published online on: 01 August 2019

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Article Open Access

Downregulated miR‑21 mediates matrine‑induced apoptosis via the PTEN/Akt signaling pathway in FTC‑133 human follicular thyroid cancer cells

Quanliang Li, Shuya Zhang, Mingyu Wang, Shouguang Dong, Yan Wang, Song Liu, Tiancheng Lu, Yuqin Fu, Xiuran Wang, Guihong Chen
Pages: 3553-3560
Published online on: 31 July 2019

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Article Open Access

The effect of YAP expression in tumor cells and tumor stroma on the prognosis of patients with squamous cell carcinoma of the oral cavity floor and oral surface of the tongue

Jolanta Szelachowska, Piotr Donizy, Katarzyna Ratajczak‑Wielgomas, Agnieszka Halon, Dominika Zielecka‑Debska, Krystian Lichon, Adam Maciejczyk, Ewelina Lata‑Wozniak, Aleksandra Piotrowska, Rafal Matkowski
Pages: 3561-3570
Published online on: 31 July 2019

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Article Open Access

Correlation analysis of expression and prognosis of TTF‑1 and CD44v6 in undifferentiated lung carcinoma

Yudong Wu, Xia Yu, Mingzhu Liang, Baojun Wang
Pages: 3571-3580
Published online on: 30 July 2019

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Article Open Access

Non‑invasive detection of EGFR and TP53 mutations through the combination of plasma, urine and sputum in advanced non‑small cell lung cancer

Zhen Wu, Zhen Yang, Chun‑Sun Li, Wei Zhao, Zhi‑Xin Liang, Yu Dai, Jing Zeng, Qiang Zhu, Kai‑Ling Miao, Dong‑Hua Cui, Liang‑An Chen
Pages: 3581-3590
Published online on: 06 August 2019

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Article Open Access

Nomogram for predicting the survival of patients with malignant melanoma: A population analysis

Jin Yang, Zhenyu Pan, Quan Zhou, Qingqing Liu, Fanfan Zhao, Xiaojie Feng, Jun Lyu
Pages: 3591-3598
Published online on: 06 August 2019

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Article Open Access

Comparison of anesthetic effects of dexmedetomidine and tramadol, respectively, combined with propofol in percutaneous microwave coagulation therapy for hepatocellular carcinoma

Chunqin Chu, Xuanlong Yi, Jian Sun, Xi Zhang, Suli Liu, Nannan Zhang, Juntao Wang
Pages: 3599-3604
Published online on: 06 August 2019

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Article Open Access

Low expression of ryanodine receptor 2 is associated with poor prognosis in thyroid carcinoma

Nizhen Xu, Deguang Zhang, Jian Chen, Gaofei He, Li Gao
Pages: 3605-3612
Published online on: 07 August 2019

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Article Open Access

Bioinformatics and functional analyses of key genes in smoking‑associated lung adenocarcinoma

Dajie Zhou, Yilin Sun, Yanfei Jia, Duanrui Liu, Jing Wang, Xiaowei Chen, Yujie Zhang, Xiaoli Ma
Pages: 3613-3622
Published online on: 07 August 2019

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Article Open Access

The oncogenic roles of 27‑hydroxycholesterol in glioblastoma Retraction in /10.3892/ol.2024.14829

Lu Liu, Mei‑Yuan Li, Yu Xing, Xiao‑Yun Wang, Yong Wang
Pages: 3623-3629
Published online on: 31 July 2019

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Article Open Access

Long non‑coding RNA LINC00152 promotes tumorigenesis via sponging miR‑193b‑3p in osteosarcoma

Pinduan Liu, Wubin He, Yanyan Lu, Yue Wang
Pages: 3630-3636
Published online on: 01 August 2019

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Article Open Access

Bioinformatics analysis identifies hub genes and pathways in nasopharyngeal carcinoma

Kang Liu, Min Kang, Ziyan Zhou, Wen Qin, Rensheng Wang
Pages: 3637-3645
Published online on: 02 August 2019

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Article Open Access

All‑trans retinoic acid therapy induces asymmetric division of glioma stem cells from the U87MG cell line

Ruizhi Wang, Chongxiao Liu
Pages: 3646-3654
Published online on: 31 July 2019

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Article Open Access

MicroRNA‑101 modulates cisplatin chemoresistance in liver cancer cells via the DNA‑PKcs signaling pathway

Zongtao Chai, Xiaolan Yin, Jin Chen, Jie Shi, Juxian Sun, Chang Liu, Feng Liu, Shuqun Cheng
Pages: 3655-3663
Published online on: 26 July 2019

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Article Open Access

Cancer stem‑like cells with increased expression of NY‑ESO‑1 initiate breast cancer metastasis

Mai‑Ying Liu, Hang Su, Hua‑Lan Huang, Jing‑Qi Chen
Pages: 3664-3672
Published online on: 01 August 2019

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Article Open Access

Identification of key modules and prognostic markers in adrenocortical carcinoma by weighted gene co‑expression network analysis

Yong Zou, Luanlian Jing
Pages: 3673-3681
Published online on: 06 August 2019

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Article Open Access

Dysregulation of N6‑methyladenosine regulators predicts poor patient survival in mantle cell lymphoma

Weilong Zhang, Xue He, Jing Hu, Ping Yang, Cuiling Liu, Jing Wang, Ran An, Jingfei Zhen, Meng Pang, Kai Hu, Xiaoyan Ke, Xiuru Zhang, Hongmei Jing
Pages: 3682-3690
Published online on: 02 August 2019

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Article Open Access

Long non‑coding RNAs as prognostic biomarkers in papillary renal cell carcinoma

Feilong Yang, Yimeng Song, Liyuan Ge, Guojiang Zhao, Cheng Liu, Lulin Ma
Pages: 3691-3697
Published online on: 29 July 2019

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Article Open Access

Elevated CD44 expression predicts poor prognosis in patients with low‑grade glioma

Qiang Dong, Qiao Li, Maolin Wang, Jianhong Hu, Junqiang Dai, Liang Niu, Guoqiang Yuan, Yawen Pan
Pages: 3698-3704
Published online on: 07 August 2019

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Article Open Access

Integrated bioinformatics analysis revealing independent prognostic long non‑coding RNAs DNAH17‑AS1 and RP11‑400N13.2 and their potential oncogenic roles in colorectal cancer

Wen Zhou, Boyu Pan, Liren Liu
Pages: 3705-3715
Published online on: 07 August 2019

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Article Open Access

Long non‑coding RNA ENST00000500843 is downregulated and promotes chemoresistance to paclitaxel in lung adenocarcinoma

Xin Tian, Song Gao, Yang Liu, Ying Xuan, Rong Wu, Zhenyong Zhang
Pages: 3716-3722
Published online on: 02 August 2019

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Article Open Access

Identification of candidate genes associated with the pathogenesis of small cell lung cancer via integrated bioinformatics analysis

Yi Liao, Guofang Yin, Xue Wang, Ping Zhong, Xianming Fan, Chengliang Huang
Pages: 3723-3733
Published online on: 29 July 2019

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Article Open Access

Association between RNF2+P‑AKT expression in pretreatment biopsy specimens, and poor survival following radiotherapy in patients with esophageal squamous cell carcinoma

Qiaofang Li, Shuguang Li, Xingxiao Yang, Xueyuan Zhang, Chunyang Song, Shuchai Zhu
Pages: 3734-3742
Published online on: 07 August 2019

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Article Open Access

MicroRNA‑300 inhibits the growth of hepatocellular carcinoma cells by downregulating CREPT/Wnt/β‑catenin signaling

Jinping Bai, Yingchun Gao, Yanhui Du, Xue Yang, Xinye Zhang
Pages: 3743-3753
Published online on: 05 August 2019

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Article Open Access

Identification of differentially expressed genes between primary lung cancer and lymph node metastasis via bioinformatic analysis

Nan Zhang, Shao‑Wei Zhang
Pages: 3754-3768
Published online on: 06 August 2019

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Article Open Access

Identification of β‑catenin target genes in colorectal cancer by interrogating gene fitness screening data

Haomin Zhao, Liang He, Dexin Yin, Bin Song
Pages: 3769-3777
Published online on: 06 August 2019

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Article Open Access

Identification of key pathways and genes in colorectal cancer to predict the prognosis based on mRNA interaction network

Hengzhou Zhu, Yi Ji, Wenting Li, Mianhua Wu
Pages: 3778-3786
Published online on: 01 August 2019

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Article Open Access

Long non‑coding RNA mortal obligate RNA transcript suppresses tumor cell proliferation in prostate carcinoma by inhibiting glucose uptake

Zhenfeng Shi, Feng Guo, Deyong Jia, Jinxing Huang, Jie Chen, Min Sun, Feibo Qi, Chengyuan Liang
Pages: 3787-3791
Published online on: 05 August 2019

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Article

MicroRNA‑23a inhibits endometrial cancer cell development by targeting SIX1 Corrigendum in /10.3892/ol.2023.14032

Hong‑Lin Li, Jun‑Jie Sun, Hui Ma, Shen‑Jia Liu, Na Li, Su‑Jie Guo, Yang Shi, Yan‑Ying Xu, Zhi‑Ying Qi, Yu‑Quan Wang, Fang Wang, Rui‑Meng Guo, Dong Liu, Feng‑Xia Xue
Pages: 3792-3802
Published online on: 31 July 2019

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Article

nm23, TOP2A and VEGF expression: Potential prognostic biologic factors in peripheral T‑cell lymphoma, not otherwise specified

Wenting Huang, Zheng Cao, Linshu Zeng, Lei Guo, Xiuyun Liu, Ning Lv, Xiaoli Feng
Pages: 3803-3810
Published online on: 02 August 2019

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Article

LINC01638 lncRNA promotes cancer cell proliferation in hepatocellular carcinoma by increasing cancer cell glucose uptake

Xiaoli Chen, Lili Wang, Hui Wang
Pages: 3811-3816
Published online on: 29 July 2019

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Article

Long non‑coding RNA DRHC inhibits the proliferation of cancer cells in triple negative breast cancer by downregulating long non‑coding RNA HOTAIR

Fusheng Yu, Lei Wang, Bowen Zhang
Pages: 3817-3822
Published online on: 29 July 2019

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Article

Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway

Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
Pages: 3823-3829
Published online on: 06 August 2019

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Article

MLKL is a potential prognostic marker in gastric cancer

Wei Sun, Wenyan Yu, Lili Shen, Tieao Huang
Pages: 3830-3836
Published online on: 29 July 2019

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Article

Loss of miR‑873 contributes to gemcitabine resistance in triple‑negative breast cancer via targeting ZEB1

Gangyue Wang, Yi Dong, Heng Liu, Nan Ji, Jilei Cao, Aihui Liu, Xin Tang, Yu Ren
Pages: 3837-3844
Published online on: 01 August 2019

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Article

The CK2 inhibitor CX4945 reverses cisplatin resistance in the A549/DDP human lung adenocarcinoma cell line

Chengji Jin, Ping Song, Ji Pang
Pages: 3845-3856
Published online on: 01 August 2019

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Article

Overexpression of MAGT1 is associated with aggressiveness and poor prognosis of colorectal cancer

Kehong Zheng, Qianqiong Yang, Lang Xie, Zhenghua Qiu, Yongsheng Huang, Yongwei Lin, Lingjing Tu, Chunhui Cui
Pages: 3857-3862
Published online on: 05 August 2019

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Article

Prediction of tumor response of rectal cancer cells via 3D cell culture and in vitro cytotoxicity assay before initiating preoperative chemoradiotherapy

Jeonghyun Kang, Min Chul Park, Jina Kim, Hyuk Hur, Byung Soh Min, Seung Hyuk Baik, Kang Young Lee, Nam Kyu Kim
Pages: 3863-3872
Published online on: 02 August 2019

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Article

Clinical and pathological factors predictive of response to neoadjuvant chemotherapy in breast cancer: A single center experience

Salvatore Del Prete, Michele Caraglia, Amalia Luce, Liliana Montella, Gennaro Galizia, Pasquale Sperlongano, Gregorio Cennamo, Eva Lieto, Elena Capasso, Olga Fiorentino, Maria Aliberti, Annamaria Auricchio, Patrizia Iodice, Raffaele Addeo
Pages: 3873-3879
Published online on: 07 August 2019

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Article

Vitamin C induces human melanoma A375 cell apoptosis via Bax‑ and Bcl‑2‑mediated mitochondrial pathways

Xiao‑Yu Chen, Ying Chen, Chuan‑Jun Qu, Zhao‑Hai Pan, Yao Qin, Xin Zhang, Wen‑Jing Liu, De‑Fang Li, Qiusheng Zheng
Pages: 3880-3886
Published online on: 29 July 2019

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Article

Prognostic value of EGFR 19‑del and 21‑L858R mutations in patients with non‑small cell lung cancer

Weiwei Hong, Qiuji Wu, Junhong Zhang, Yunfeng Zhou
Pages: 3887-3895
Published online on: 06 August 2019

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Article

Clinical and oncological outcomes of robot‑assisted radical prostatectomy with nerve sparing vs. non‑nerve sparing for high‑risk prostate cancer cases

Kiyoshi Takahara, Makoto Sumitomo, Kosuke Fukaya, Takahito Jyoudai, Masashi Nishino, Masaru Hikichi, Kenji Zennami, Takuhisa Nukaya, Manabu Ichino, Naohiko Fukami, Hitomi Sasaki, Mamoru Kusaka, Ryoichi Shiroki
Pages: 3896-3902
Published online on: 31 July 2019

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Article

Utility of scoring systems combining the product of tumor number and size with liver function for predicting the prognosis of patients with hepatocellular carcinoma after hepatectomy

Yukio Tokumitsu, Yoshitaro Shindo, Hiroto Matsui, Satoshi Matsukuma, Masao Nakajima, Nobuaki Suzuki, Shigeru Takeda, Hiroshi Wada, Shogo Kobayashi, Hidetoshi Eguchi, Tomio Ueno, Hiroaki Nagano
Pages: 3903-3913
Published online on: 29 July 2019

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Article

Patients with BRCA mutated ovarian cancer may have fewer circulating MDSC and more peripheral CD8+ T cells compared with women with BRCA wild‑type disease during the early disease course

Jung‑Min Lee, Dana‑Adriana Botesteanu, Yusuke Tomita, Akira Yuno, Min‑Jung Lee, Elise C. Kohn, Christina M. Annunziata, Ursula Matulonis, Lauren A. MacDonald, Jayakumar R. Nair, Kimberley M. Macneil, Jane B. Trepel
Pages: 3914-3924
Published online on: 07 August 2019

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Review Open Access

Role of tumor‑derived exosomes in bone metastasis (Review)

Fu‑Xing‑Zi Li, Jun‑Jie Liu, Feng Xu, Xiao Lin, Jia‑Yu Zhong, Feng Wu, Ling‑Qing Yuan
Pages: 3935-3945
Published online on: 22 August 2019

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Review Open Access

Role of stanniocalcin‑1 in breast cancer (Review)

Fengxia Chen, Zhicai Zhang, Feifei Pu
Pages: 3946-3953
Published online on: 22 August 2019

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Review

C‑type lectin family XIV members and angiogenesis (Review)

Supriya Borah, Dileep Vasudevan, Rajeeb K. Swain
Pages: 3954-3962
Published online on: 16 August 2019

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Review Open Access

Role of non‑coding RNA in pancreatic cancer (Review)

Yinghao Lv, Shuai Huang
Pages: 3963-3973
Published online on: 16 August 2019

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Review Open Access

Prospective applications of microRNAs in oral cancer (Review)

Chuan Fang, Yadong Li
Pages: 3974-3984
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NEDD9 promotes invasion and migration of colorectal cancer cell line HCT116 via JNK/EMT

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MicroRNA‑544 inhibits esophageal squamous cell carcinoma cell proliferation and enhances sensitivity to cisplatin by repressing E2F transcription factor 5

Fengrong Sun, Cuiping Zhang, Deliang Ma, Kai Wang
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Linwei Zhang, Lingxin Feng, Hui Cong, Zhuang Yu, Haocheng Wang, Ya Dong, Jing Wang
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Prognostic significance of TPX2 and NIBP in esophageal cancer

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Effect of morphine and a low dose of ketamine on the T cells of patients with refractory cancer pain in vitro

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Identification of potential diagnostic and prognostic biomarkers for prostate cancer

Qiang Zhang, Xiujuan Yin, Zhiwei Pan, Yingying Cao, Shaojie Han, Guojun Gao, Zhiqin Gao, Zhifang Pan, Weiguo Feng
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LncRNA AWPPH participates in the metastasis of non‑small cell lung cancer by upregulating TGF‑β1 expression

Yanxia Huo, Aimin Li, Zhihua Wang
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Sulforaphane enhances apoptosis induced by Lactobacillus pentosus strain S‑PT84 via the TNFα pathway in human colon cancer cells

Shusuke Yasuda, Mano Horinaka, Toshiyuki Sakai
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Causal associations of autoimmune thyroiditis and papillary thyroid carcinoma: mRNA expression of selected nuclear receptors and other molecular targets

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Huaming Huang, Chao Nie, Xiaokang Qin, Jie Zhou, Lei Zhang
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Published online on: 23 August 2019

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MicroRNA‑98‑5p regulates the proliferation and apoptosis of A549 cells by targeting MAP4K3

Ziquan Wang, Zhengxiang Han, Lansheng Zhang, Shiqiang Zhang, Baoqing Wang
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MDIG promotes cisplatin resistance of lung adenocarcinoma by regulating ABC transporter expression via activation of the WNT/β‑catenin signaling pathway

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DZNep inhibits Hif‑1α and Wnt signalling molecules to attenuate the proliferation and invasion of BGC‑823 gastric cancer cells

Rui Huang, Xiu Jin, Yongying Gao, Hongmei Yuan, Fei Wang, Xiangmei Cao
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Leukemia stem cells promote chemoresistance by inducing downregulation of lumican in mesenchymal stem cells

Zhen Yu, Lin Liu, Qiang Shu, Dong Li, Ran Wang
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Effects of ABT‑737 combined with irradiation treatment on uterine cervical cancer cells

Huang‑Pin Shen, Wen‑Jun Wu, Jiunn‑Liang Ko, Tzu‑Fan Wu, Shun‑Fa Yang, Chih‑Hsien Wu, Chia‑Ming Yeh, Po‑Hui Wang
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Dysregulation of the miRNA biogenesis components DICER1, DROSHA, DGCR8 and AGO2 in clear cell renal cell carcinoma in both a Korean cohort and the cancer genome atlas kidney clear cell carcinoma cohort

Sang Su Lee, Hyeonji Min, Ji Yong Ha, Byung Hoon Kim, Mi Sun Choi, Shin Kim
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21‑Gene recurrence score influences the chemotherapy decision for patients with breast cancer of different luminal subtypes

Wei Wang, Lin Lin, Xiaochun Fei, Jin Hong, Weiqi Gao, Siji Zhu, Jiayi Wu, Ou Huang, Jianrong He, Yafen Li, Li Zhu, Weiguo Chen, Xiaosong Chen, Kunwei Shen
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Correction Open Access

[Corrigendum] High TNF‑α and/or p38MAPK expression predicts a favourable prognosis in patients with T1N0M0 hepatocellular carcinoma: An immunohistochemical study

Mao Zhang, Jie Hu, Haoran Li, Shun Zhang, Weiyu Hu, Liqun Wu, Bing Han
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Published online on: 23 August 2019

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
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Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
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A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
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Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
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[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
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Published online on: 23 March 2026

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Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
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Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
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Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
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[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
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Published online on: 17 March 2026

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Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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