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Article Open Access

Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types

  • Authors:
    • Yasunari Miyagi
    • Kazuhiro Takehara
    • Yoko Nagayasu
    • Takahito Miyake
  • View Affiliations / Copyright

    Affiliations: Medical Data Labo, Okayama, Okayama 703‑8267, Japan, Department of Gynecologic Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime 791‑0208, Japan, Department of Obstetrics and Gynecology, Miyake Clinic, Okayama, Okayama 701‑0204, Japan
    Copyright: © Miyagi et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1602-1610
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    Published online on: December 12, 2019
       https://doi.org/10.3892/ol.2019.11214
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Abstract

The aim of the present study was to explore the feasibility of using deep learning, such as artificial intelligence (AI), to classify cervical squamous epithelial lesions (SILs) from colposcopy images combined with human papilloma virus (HPV) types. Among 330 patients who underwent colposcopy and biopsy performed by gynecological oncologists, a total of 253 patients with confirmed HPV typing tests were enrolled in the present study. Of these patients, 210 were diagnosed with high‑grade SIL (HSIL) and 43 were diagnosed with low‑grade SIL (LSIL). An original AI classifier with a convolutional neural network catenating with an HPV tensor was developed and trained. The accuracy of the AI classifier and gynecological oncologists was 0.941 and 0.843, respectively. The AI classifier performed better compared with the oncologists, although not significantly. The sensitivity, specificity, positive predictive value, negative predictive value, Youden's J index and the area under the receiver‑operating characteristic curve ± standard error for AI colposcopy combined with HPV types and pathological results were 0.956 (43/45), 0.833 (5/6), 0.977 (43/44), 0.714 (5/7), 0.789 and 0.963±0.026, respectively. Although further study is required, the clinical use of AI for the classification of HSIL/LSIL by both colposcopy and HPV type may be feasible.
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1 

Müller VC and Bostrom N: Future progress in artificial intelligence: A survey of expert opinion. In: Fundamental Issues of Artificial Intelligence. Springer; Cham: pp. 555–572. 2016

2 

Silver D, Schrittwieser J, Simonyan K, Antonoglou I, Huang A, Guez A, Hubert T, Baker L, Lai M, Bolton A, et al: Mastering the game of go without human knowledge. Nature. 550:354–359. 2017. View Article : Google Scholar : PubMed/NCBI

3 

Miyagi Y, Takehara K and Miyake T: Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images. Mol Clin Oncol. 11:583–589. 2019.PubMed/NCBI

4 

Miyagi Y, Habara T, Hirata R and Hayashi N: Feasibility of predicting live birth by combining conventional embryo evaluation with artificial intelligence applied to a blastocyst image in patients classified by age. Reprod Med Biol. 18:344–356. 2019. View Article : Google Scholar : PubMed/NCBI

5 

Arbyn M, Castellsagué X, de Sanjosé S, Bruni L, Saraiya M, Bray F and Ferlay J: Worldwide burden of cervical cancer in 2008. Ann Oncol. 22:2675–2686. 2011. View Article : Google Scholar : PubMed/NCBI

6 

García-Arteaga JD, Kybic J and Li W: Automatic colposcopy video tissue classification using higher order entropy-based image registration. Comput Biol Med. 41:960–970. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Kyrgiou M, Tsoumpou I, Vrekoussis T, Martin-Hirsch P, Arbyn M, Prendiville W, Mitrou S, Koliopoulos G, Dalkalitsis N, Stamatopoulos P and Paraskevaidis E: The up-to-date evidence on colposcopy practice and treatment of cervical intraepithelial neoplasia: The Cochrane colposcopy and cervical cytopathology collaborative group (C5 group) approach. Cancer Treat Rev. 32:516–523. 2006. View Article : Google Scholar : PubMed/NCBI

8 

O'Neill E, Reeves MF and Creinin MD: Baseline colposcopic findings in women entering studies on female vaginal products. Contraception. 78:162–166. 2008. View Article : Google Scholar : PubMed/NCBI

9 

Waxman AG, Chelmow D, Darragh TM, Lawson H and Moscicki AB: Revised terminology for cervical histopathology and its implications for management of high-grade squamous intraepithelial lesions of the cervix. Obstet Gynecol. 120:1465–1471. 2012. View Article : Google Scholar : PubMed/NCBI

10 

Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, et al: Members of the LAST project work groups. The lower anogenital squamous terminology standardization project for HPV-associated lesions: Background and consensus recommendations from the College of American Pathologists and the American society for colposcopy and cervical pathology. Int J Gynecol Pathol. 32:76–115. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Burd EM: Human papillomavirus and cervical cancer. Clin Microbiol Rev. 16:1–17. 2003. View Article : Google Scholar : PubMed/NCBI

12 

Rumelhart D, Hinton G and Williams R: Learning representations by back-propagating errors. Nature. 323:533–536. 1986. View Article : Google Scholar

13 

Bengio Y, Courville A and Vincent P: Representation learning: A review and new perspectives. IEEE Trans Pattern Anal Mach Intell. 35:1798–1828. 2013. View Article : Google Scholar : PubMed/NCBI

14 

Schmidhuber J: Deep learning in neural networks: An overview. Neural Netw. 61:85–117. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Srivastava N, Hinton G, Krizhevsky A, Sutskever I and Salakhutdinov R: Dropout: A simple way to prevent neural networks from overfitting. J Mach Lean Res. 15:1929–1958. 2014.

16 

Nowlan SJ and Hinton GE: Simplifying neural networks by soft weight-sharing. Neural Comput. 4:473–493. 1992. View Article : Google Scholar

17 

Bengio Y: Learning deep architectures for AI. Foundations and trends® in machine learning. 2:1–127. 2009. View Article : Google Scholar

18 

Mutch J and Lowe DG: Object class recognition and localization using sparse features with limited receptive fields. Int J Comput Vision. 80:45–57. 2008. View Article : Google Scholar

19 

Neal RM: Connectionist learning of belief networks. Art Intell. 56:71–113. 1992. View Article : Google Scholar

20 

Ciresan DC, Meier U, Masci J, Maria Gambardella L and Schmidhuber J: Flexible, high performance convolutional neural networks for image classification. IJCAI'11 Proceedings of the Twenty-Second international joint conference on artificial intelligence. 2:1237–1242. 2011.

21 

Scherer D, Müller A and Behnke S: Evaluation of pooling operations in convolutional architectures for object recognition. Artificial Neural Networks-ICANN 2010. Diamantaras K, Duch W and Iliadis LS: Lecture Notes in Computer Science Springer; Heidelberg: pp. 92–101. 2010, View Article : Google Scholar

22 

Huang FJ and LeCun Y: Large-scale learning with SVM and convolutional for generic object categorization. Computer Vision and Pattern Recognition, 2006 IEEE Computer Society Conference. 1:284–291. 2006.

23 

Jarrett K, Kavukcuoglu K, Ranzato M and LeCun Y: What is the best multi-stage architecture for object recognition? Computer vision. 12th IEEE international conference on computer vision. 2146–2153. 2009.

24 

Zheng Y, Liu Q, Chen E, Ge Y and Zhao JL: Time series classification using multi-channels deep convolutional neural networks. Web-Age Information Management. WAIM 2014. Lecture notes in computer science. Li F, Li G, Hwang S, Yao B and Zhang Z: Springer; Cham: pp. 298–310. 2014

25 

Mnih V, Kavukcuoglu K, Silver D, Rusu AA, Veness J, Bellemare MG, Graves A, Riedmiller M, Fidjeland AK, Ostrovski G, et al: Human-level control through deep reinforcement learning. Nature. 518:529–533. 2015. View Article : Google Scholar : PubMed/NCBI

26 

Szegedy C, Liu W, Jia Y, Sermanet P, Reed S, Anguelov D, Erhan D, Vanhoucke V and Rabinovich A: Going deeper with convolutions. Proceedings of the IEEE conference on computer vision and pattern recognition. 1–9. 2015.

27 

Glorot X, Bordes A and Bengio Y: Deep sparse rectifier neural networks. Proceedings of the fourteenth international conference on artificial intelligence and statistics PMLR. 15:315–323. 2011.

28 

Nair V and Hinton G: Rectified linear units improve restricted Boltzmann machines. Proceedings of the 27th International Conference on Machine Learning Haifa. 807–814. 2010.

29 

Ioffe S and Szegedy C: Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift. 32nd International Conference on Machine Learning Lille: 2015

30 

Krizhevsky A, Sutskever I and Hinton GE: ImageNet Classification with Deep Convolutional Neural Networks. 25th International Conference on Neural Information Processing Systems. 1097–1105. 2012.

31 

Bridle JS: Probabilistic interpretation of feedforward classification network outputs, with relationships to statistical pattern recognition. Neurocomputing. Soulié FF and Hérault J: Springer; Berlin: pp. 227–236. 1990, View Article : Google Scholar

32 

Kohavi R: A study of cross-validation and bootstrap for accuracy estimation and model selection. Proceedings of the 14th international joint conference on artificial intelligence. 2:1137–1143. 1195.

33 

Schaffer C: Selecting a classification method by cross-validation. Mach Lear. 13:135–143. 1993. View Article : Google Scholar

34 

Refaeilzadeh P, Tang L and Liu H: Cross-Validation. Encyclopedia of Database Systems. Liu L and Özsu MT: Springer; Boston: pp. 532–538. 2009

35 

Yu L, Chen H, Dou Q, Qin J and Heng PA: Automated melanoma recognition in dermoscopy images via very deep residual networks. IEEE Trans Med Imaging. 36:994–1004. 2017. View Article : Google Scholar : PubMed/NCBI

36 

Caruana R, Lawrence S and Giles CL: Overfitting in neural nets: Backpropagation, conjugate gradient, and early stopping. Advances in neural information processing systems. 13:402–408. 2001.

37 

Baum EB and Haussler D: What size net gives valid generalization? Neural Computation. 1:151–160. 1989. View Article : Google Scholar

38 

Geman S, Bienenstock E and Doursat R: Neural networks and the bias/variance dilemma. Neural Computation. 4:1–58. 1992. View Article : Google Scholar

39 

Krogh A and Hertz JA: A simple weight decay can improve generalization. In Advances in neural information processing systems. 4:950–957. 1992.

40 

Moody JE: The effective number of parameters: An analysis of generalization and regularization in nonlinear learning systems. Advances in Neural Information Processing Systems. Moody JE, Hanson SJ and Lippmann RP: Morgan Kaufmann Publishers Inc.; San Francisco, CA: pp. 847–854. 1992

41 

Youden WJ: Index for rating diagnostic tests. Cancer. 3:32–35. 1950. View Article : Google Scholar : PubMed/NCBI

42 

Cohen J: A coefficient of agreement for nominal scales. Educ Psychol Meas. 20:37–46. 1960. View Article : Google Scholar

43 

McHugh ML: Interrater reliability: The kappa statistic. Biochem Med (Zagreb). 22:276–282. 2012. View Article : Google Scholar : PubMed/NCBI

44 

Poljak M, Kovanda A, Kocjan BJ, Seme K, Jancar N and Vrtacnik-Bokal E: The abbott RealTime high risk HPV test: Comparative evaluation of analytical specificity and clinical sensitivity for cervical carcinoma and CIN 3 lesions with the Hybrid Capture 2 HPV DNA test. Acta Dermatovenerol Alp Pannonica Adriat. 18:94–103. 2009.PubMed/NCBI

45 

Tjalma WA, Fiander A, Reich O, Powell N, Nowakowski AM, Kirschner B, Koiss R, O'Leary J, Joura EA, Rosenlund M, et al: Differences in human papillomavirus type distribution in high-grade cervical intraepithelial neoplasia and invasive cervical cancer in Europe. Int J Cancer. 132:854–867. 2013. View Article : Google Scholar : PubMed/NCBI

46 

De Sanjose S, Quint WG, Alemany L, Geraets DT, Klaustermeier JE, Lloveras B, Tous S, Felix A, Bravo LE, Shin HR, et al: Human papillomavirus genotype attribution in invasive cervical cancer: A retrospective cross-sectional worldwide study. Lancet Oncol. 11:1048–1056. 2010. View Article : Google Scholar : PubMed/NCBI

47 

Lee SH, Vigliotti JS, Vigliotti VS and Jones W: From human papillomavirus (HPV) detection to cervical cancer prevention in clinical practice. Cancers (Basel). 6:2072–2099. 2014. View Article : Google Scholar : PubMed/NCBI

48 

Miyagi Y, Fujiwara K, Oda T, Miyake T and Coleman RL: Development of new method for the prediction of clinical trial results using compressive sensing of artificial intelligence. J Biostat Biometric App. 3:2032018.

49 

Abbod MF, Catto JW, Linkens DA and Hamdy FC: Application of artificial intelligence to the management of urological cancer. J Urol. 178:1150–1156. 2007. View Article : Google Scholar : PubMed/NCBI

50 

Litjens G, Sánchez CI, Timofeeva N, Hermsen M, Nagtegaal I, Kovacs I, Hulsbergen-Van De Kaa C, Bult P, Van Ginneken B and van der Laak J: Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis. Sci Rep. 6:262862016. View Article : Google Scholar : PubMed/NCBI

51 

Khosravi P, Kazemi E, Zhan Q, Toschi M, Malmsten JE, Hickman C, Meseguer M, Rosenwaks Z, Elemento O, Zaninovic N and Hajirasouliha I: Robust automated assessment of human blastocyst quality using deep learning. BioRxiv. 3948822018.

52 

Miyagi Y, Habara T, Hirata R and Hayashi N: Feasibility of deep learning for predicting live birth from a blastocyst image in patients classified by age. Reprod Med Biol. 18:190–203. 2019. View Article : Google Scholar : PubMed/NCBI

53 

Miyagi Y, Habara T, Hirata R and Hayashi N: Feasibility of artificial intelligence for predicting live birth without aneuploidy from a blastocyst image. Reprod Med Biol. 18:204–211. 2019. View Article : Google Scholar : PubMed/NCBI

54 

Simões PW, Izumi NB, Casagrande RS, Venson R, Veronezi CD, Moretti GP, da Rocha EL, Cechinel C, Ceretta LB, Comunello E, et al: Classification of images acquired with colposcopy using artificial neural networks. Cancer Inform. 13:119–124. 2014. View Article : Google Scholar : PubMed/NCBI

55 

Sato M, Horie K, Hara A, Miyamoto Y, Kurihara K, Tomio K and Yokota H: Application of deep learning to the classification of images from colposcopy. Oncol Lett. 15:3518–3523. 2018.PubMed/NCBI

56 

Ortiz A, Munilla J, Gorriz JM and Ramirez J: Ensembles of deep learning architectures for the early diagnosis of the Alzheimer's disease. Int J Neural Syst. 26:16500252016. View Article : Google Scholar : PubMed/NCBI

57 

Gil D, Johnsson M, Chamizo JMG, Paya AS and Fernandez DR: Application of artificial neural networks in the diagnosis of urological disfunctions. Expert Syst Appl. 36:5754–5760. 2009. View Article : Google Scholar

58 

Olczak J, Fahlberg N, Maki A, Razavian AS, Jilert A, Stark A, Sköldenberg O and Gordon M: Artificial intelligence for analyzing orthopedic trauma radiographs. Acta Orthop. 88:581–586. 2017. View Article : Google Scholar : PubMed/NCBI

59 

Sideri M, Garutti P, Costa S, Cristiani P, Schincaglia P, Sassoli de Bianchi P, Naldoni C and Bucchi L: Accuracy of colposcopically directed biopsy: Results from an online quality assurance programme for colposcopy in a population-based cervical screening setting in Italy. Biomed Res Int. 2015:6140352015. View Article : Google Scholar : PubMed/NCBI

60 

Sideri M, Spolti N, Spinaci L, Sanvito F, Ribaldone R, Surico N and Bucchi L: Interobserver variability of colposcopic interpretations and consistency with final histologic results. J Lower Genital Tract Dis. 8:212–216. 2004. View Article : Google Scholar

61 

Massad LS, Jeronimo J, Katki HA and Schiffman M; National Institutes of Health/American Society for Colposcopy and Cervical Pathology Research Group, : The accuracy of colposcopic grading for detection of high-grade cervical intraepithelial neoplasia. J Lower Genital Tract Dis. 13:137–144. 2009. View Article : Google Scholar

62 

LeCun Y, Haffner P, Bottou L and Bengio Y: Object recognition with gradient-based learning. Shape, contour and grouping in computer vision. Lecture Notes in Computer Science. Springer, Berlin, Heidelberg. 1681:319–345. 1999.

63 

He K, Zhang X, Ren S and Sun J: Deep residual learning for image recognition. Proceedings of the IEEE conference on computer vision and pattern recognition. 770–778. 2016.PubMed/NCBI

64 

Hu J, Shen L and Sun G: Squeeze-and-excitation networks. Proceedings of the IEEE conference on computer vision and pattern recognition. 7132–7141. 2018.

65 

Kudva V, Prasad K and Guruvare S: Automation of detection of cervical cancer using convolutional neural networks. Crit Rev Biomed Eng. 46:135–145. 2018. View Article : Google Scholar : PubMed/NCBI

66 

Esteva A, Kuprel B, Novoa RA, Ko J, Swetter SM, Blau HM and Thrun S: Dermatologist-level classification of skin cancer with deep neural networks. Nature. 542:115–118. 2017. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Miyagi Y, Takehara K, Nagayasu Y and Miyake T: Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types. Oncol Lett 19: 1602-1610, 2020.
APA
Miyagi, Y., Takehara, K., Nagayasu, Y., & Miyake, T. (2020). Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types. Oncology Letters, 19, 1602-1610. https://doi.org/10.3892/ol.2019.11214
MLA
Miyagi, Y., Takehara, K., Nagayasu, Y., Miyake, T."Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types". Oncology Letters 19.2 (2020): 1602-1610.
Chicago
Miyagi, Y., Takehara, K., Nagayasu, Y., Miyake, T."Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types". Oncology Letters 19, no. 2 (2020): 1602-1610. https://doi.org/10.3892/ol.2019.11214
Copy and paste a formatted citation
x
Spandidos Publications style
Miyagi Y, Takehara K, Nagayasu Y and Miyake T: Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types. Oncol Lett 19: 1602-1610, 2020.
APA
Miyagi, Y., Takehara, K., Nagayasu, Y., & Miyake, T. (2020). Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types. Oncology Letters, 19, 1602-1610. https://doi.org/10.3892/ol.2019.11214
MLA
Miyagi, Y., Takehara, K., Nagayasu, Y., Miyake, T."Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types". Oncology Letters 19.2 (2020): 1602-1610.
Chicago
Miyagi, Y., Takehara, K., Nagayasu, Y., Miyake, T."Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types". Oncology Letters 19, no. 2 (2020): 1602-1610. https://doi.org/10.3892/ol.2019.11214
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