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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2020 Volume 19 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Biology and pathogenesis of human osteosarcoma (Review)

Judson Welber Veríssimo de Azevedo, Thales Allyrio Araújo de Medeiros Fernandes, José Veríssimo Fernandes, Jenner Chrystian Veríssimo de Azevedo, Daniel Carlos Ferreira Lanza, Christiane Medeiros Bezerra, Vânia Sousa Andrade, Josélio Maria Galvão de Araújo, José Veríssimo Fernandes
Pages: 1099-1116
Published online on: 18 December 2019

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Article Open Access

Role of Gd2O3‑doped carbon‑11‑choline‑lenvatinib nanoparticles contrast agent PET/CT in the diagnosis of patients with lung cancer

Tong Zhou, Dongfang Hang, Ying Li, Jin Zhang, Huayang Wu, Hongyan Wang, Enbing Tian, Jun Yan
Pages: 1117-1124
Published online on: 23 December 2019

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Article Open Access

Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands

Jovanna Thielker, Anja Weise, Moneeb A.K. Othman, Isabel M. Carreria, Joana B. Melo, Ferdinand von Eggeling, Orlando Guntinas‑Lichius, Monika Ziegler, Thomas Liehr
Pages: 1125-1130
Published online on: 10 December 2019

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Article Open Access

Long non‑coding RNA mortal obligate RNA transcript inhibits the migration and invasion of colon cancer cells by inactivating transforming growth factor β1

Taicheng Zhou, Lili Wu, Zhen Zong, Ning Ma, Yingru Li, Zhipeng Jiang, Qirui Wang, Shuang Chen
Pages: 1131-1136
Published online on: 09 December 2019

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Article Open Access

Targeted molecular profiling of genetic alterations in colorectal cancer using next‑generation sequencing

Jia Luo, Shengjun Zhang, Meihua Tan, Jia Li, Huadong Xu, Yanfei Tan, Yue Huang
Pages: 1137-1144
Published online on: 10 December 2019

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Article Open Access

Downregulation of long non‑coding RNA NR2F2‑AS1 inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells by upregulating the expression of PTEN

He Qin, Chong Qin
Pages: 1145-1150
Published online on: 12 December 2019

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Article Open Access

Effect of dexmedetomidine on the cognitive function of patients undergoing gastric cancer surgery by regulating the PI3K/AKT signaling pathway

Zhiyuan Wang, Zijin Shen, Haibin Wang, Lin Zhang, Rong Dong
Pages: 1151-1156
Published online on: 18 December 2019

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Article Open Access

Downregulation of LINC01140 is associated with adverse features of breast cancer

Deheng Li, Liangdong Li, Yiqun Cao, Xin Chen
Pages: 1157-1164
Published online on: 25 November 2019

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Article Open Access

Diagnostic accuracy of urinary survivin mRNA expression detected by RT‑PCR compared with urine cytology in the detection of bladder cancer: A meta‑analysis of diagnostic test accuracy in head‑to‑head studies

Liang Fu, Jiwang Zhang, Ling Li, Yuxing Yang, Yongqiang Yuan
Pages: 1165-1174
Published online on: 18 December 2019

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Article Open Access

Time‑series clustering of cytokine expression after transarterial chemoembolization in patients with hepatocellular carcinoma

Feng Qi, Lingxiao Wang, Peixin Huang, Zhiying Zhao, Biwei Yang, Jinglin Xia
Pages: 1175-1186
Published online on: 11 December 2019

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Article Open Access

Effects of propofol and sevoflurane on blood glucose, hemodynamics, and inflammatory factors of patients with type 2 diabetes mellitus and gastric cancer

Jinhui Liu, Li Yang
Pages: 1187-1194
Published online on: 10 December 2019

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Article Open Access

Effects of miR‑129‑3p on biological functions of prostate cancer cells through targeted regulation of Smad3

Yunpeng Jia, Yu Gao, Jianguo Dou
Pages: 1195-1202
Published online on: 13 December 2019

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Article Open Access

Effects of hub genes on the clinicopathological and prognostic features of lung adenocarcinoma

Dong‑Hu Yu, Jing‑Yu Huang, Xiao‑Ping Liu, Xiao‑Lan Ruan, Chen Chen, Wei‑Dong Hu, Sheng Li
Pages: 1203-1214
Published online on: 09 December 2019

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Article Open Access

Identification of osteosarcoma driver genes using a network method

Zebing Si , Konghe Hu
Pages: 1215-1222
Published online on: 12 December 2019

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Article Open Access

PD‑L1 gene promoter methylation represents a potential diagnostic marker in advanced gastric cancer

Dan Lv, Chengjuan Xing, Lin Cao, Yuejian Zhuo, Tao Wu, Na Gao
Pages: 1223-1234
Published online on: 16 December 2019

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Article Open Access

Prognostic significance of peritumoral fibrosis after resection of pancreatic head cancer

Peng Chen, Youmei Wang, Xiaosan Fang, Xiaoming Wang, Guannan Wang
Pages: 1235-1240
Published online on: 04 December 2019

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Article Open Access

Expression levels of ARHI and Beclin1 in thyroid cancer and their relationship with clinical pathology and prognosis

Houwei Zhu, Yanqing Qu
Pages: 1241-1246
Published online on: 17 December 2019

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Article Open Access

BMP4 induces asymmetric cell division in human glioma stem-like cells

Motofumi Koguchi, Yukiko Nakahara, Hiroshi Ito, Tomihiro Wakamiya, Fumitaka Yoshioka, Atsushi Ogata, Kohei Inoue, Jun Masuoka, Hideki Izumi, Tatsuya Abe
Pages: 1247-1254
Published online on: 20 December 2019

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Article Open Access

Long non‑coding RNA TTN‑AS1 promotes breast cancer cell migration and invasion via sponging miR‑140‑5p Retraction in /10.3892/ol.2020.12018

Jie Xue, Zhixia Zhang, Xiaona Li, Qingfang Ren, Qinghua Wang
Pages: 1255-1260
Published online on: 17 December 2019

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Article Open Access

Regulation of lncRNA PVT1 on miR-125 in metastasis of gastric cancer cells Retraction in /10.3892/ol.2025.15209

Jiatai Niu, Xiangxin Song, Xiaomei Zhang
Pages: 1261-1266
Published online on: 10 December 2019

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Article Open Access

lncRNA PVT1 accelerates progression of non‑small cell lung cancer via targeting miRNA‑526b/EZH2 regulatory loop

Chun Qiu, Sai Li, Datong Sun, Shenghui Yang
Pages: 1267-1272
Published online on: 20 December 2019

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Article Open Access

Expression of miR‑34a and Ki67 in nasopharyngeal carcinoma and the relationship with clinicopathological features and prognosis

Linqi Wei, Chao Shi, Yonghong Zhang
Pages: 1273-1280
Published online on: 13 December 2019

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Article Open Access

Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer

Yakun Hu, Yuchen Yan, Yang Xu, He Yang, Lisha Fang, Yongli Liu, Xin Li, Qiang Li, Hongchao Yan
Pages: 1281-1290
Published online on: 12 December 2019

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Article Open Access

Bone morphogenic proteins‑2, ‑4, ‑6 and 7 in non‑muscle invasive bladder cancer

Tvrtko Hudolin, Zeljko Kastelan, Ahmad El‑Saleh, Mirko Bakula, Marijana Coric, Petar Kes, Davor Tomas, Nikolina Basic‑Jukic
Pages: 1291-1297
Published online on: 13 December 2019

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Article Open Access

Involvement of the TGF-β1 pathway in caveolin-1-associated regulation of head and neck tumor cell metastasis

Jinjie Sun, Yongtian Lu, Changyun Yu, Ting Xu, Guohui Nie, Beiping Miao, Xin Zhang
Pages: 1298-1304
Published online on: 06 December 2019

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Article Open Access

mi‑R4435‑2HG promotes proliferation and inhibits apoptosis of cancer cells in ovarian carcinoma by upregulating ROCK2

Jinghui Hu, Li Wang, Wei Zhao, Yujie Huang, Zhe Wang, Heping Shen
Pages: 1305-1309
Published online on: 11 December 2019

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Article Open Access

Influence of miR‑101 on proliferation of liver cancer cells through the MAPK/ERK signaling pathway

Xuan Meng, Yong Shi, Xin Xiang, Chonghui Li, Xinlan Ge, Ke Pan, Yurong Liang
Pages: 1310-1316
Published online on: 12 December 2019

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Article Open Access

Evaluation of azacitidine in patients with transplant‑ineligible myelodysplastic syndromes and acute myeloid leukemia with myelodysplasia‑related changes in a Japanese clinical setting

Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Pages: 1317-1321
Published online on: 18 December 2019

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Article Open Access

IDH1‑R132H mutation radiosensitizes U87MG glioma cells via epigenetic downregulation of TIGAR

Narui Yin, Ting Xie, Haowen Zhang, Jian Chen, Jiahua Yu, Fenju Liu
Pages: 1322-1330
Published online on: 25 November 2019

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Article Open Access

Evaluation of heavy metals and metabolites in the urine of patients with breast cancer

Yuhao Men, Ling Li, Fen Zhang, Xueyuan Kong, Weidong Zhang, Chongli Hao, Guotian Wang
Pages: 1331-1337
Published online on: 11 December 2019

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Article Open Access

Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen‑125 secretion in ovarian carcinoma

Stephanie Antoun, David Atallah, Roula Tahtouh, Mona Diab Assaf, Malak Moubarak, Eliane Nasser Ayoub, Georges Chahine, George Hilal
Pages: 1338-1350
Published online on: 20 December 2019

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Article Open Access

A novel risk score model for stomach adenocarcinoma based on the expression levels of 10 genes

Encui Guan, Feng Tian, Zhaoxia Liu
Pages: 1351-1367
Published online on: 09 December 2019

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Article Open Access

Centromere protein F and Forkhead box M1 correlation with prognosis of non‑small cell lung cancer

Rui Li, Xia Wang, Xiaoqian Zhao, Xiaohong Zhang, Honghai Chen, Yue Ma, Yandong Liu
Pages: 1368-1374
Published online on: 20 December 2019

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Article Open Access

Integrated bioinformatics analysis to screen hub genes in the lymph node metastasis of thyroid cancer

Si Lu, Rongjie Zhao, Jie Shen, Yu Zhang, Jingjing Shi, Chenke Xu, Jiali Chen, Renbin Lin, Weidong Han, Dingcun Luo
Pages: 1375-1383
Published online on: 06 December 2019

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Article Open Access

A natural compound obtained from Valeriana jatamansi selectively inhibits glioma stem cells

Shi‑Gang Qi, Li‑Qiu Quan, Xiao‑Yue Cui, Hong‑Mei Li, Xu‑Dong Zhao, Rong‑Tao Li
Pages: 1384-1392
Published online on: 23 December 2019

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Article Open Access

Cardamonin as a potential treatment for melanoma induces human melanoma cell apoptosis

Yuyang Yue, Lijuan Liu, Peipei Liu, Yuting Li, Haitao Lu, Yanjia Li, Guoqiang Zhang, Xinsuo Duan
Pages: 1393-1399
Published online on: 23 December 2019

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Article Open Access

TRIM59 as a novel molecular biomarker to predict the prognosis of patients with NSCLC

Ming Lou, Zhaojia Gao, Tao Zhu, Xiaoliang Mao, Yeming Wang, Kai Yuan, Jichun Tong
Pages: 1400-1408
Published online on: 10 December 2019

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Article Open Access

Targeting of TLE3 by miR‑3677 in human breast cancer promotes cell proliferation, migration and invasion Retraction in /10.3892/ol.2024.14840

Li‑Na Peng, Xing‑Yan Deng, Xiao‑Xiong Gan, Jin‑Hui Zhang, Guang‑Hui Ren, Fei Shen, Jian‑Hua Feng, Wen‑Song Cai, Bo Xu
Pages: 1409-1417
Published online on: 23 December 2019

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Article Open Access

MicroRNA‑608 promotes apoptosis via BRD4 downregulation in pancreatic ductal adenocarcinoma

Maoyuan Li, Ting Li, Weidong Ma, Xiuchao Wang, Gang Zhao
Pages: 1418-1426
Published online on: 31 December 2019

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Article Open Access

MicroRNA‑519 inhibits hypoxia‑induced tumorigenesis of pancreatic cancer by regulating immune checkpoint PD‑L1

Kate Nong, Dong Zhang, Changze Chen, Yue Yang, Yong Yang, Shengyong Liu, Huihua Cai
Pages: 1427-1433
Published online on: 20 December 2019

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Article Open Access

Bioinformatics analysis of esophageal cancer unveils an integrated mRNA‑lncRNA signature for predicting prognosis

Tian Lan, Zunqiang Xiao, Hua Luo, Kunlun Su, Ouou Yang, Chengni Zhan, Yunyan Lu
Pages: 1434-1442
Published online on: 11 December 2019

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Article Open Access

Survival prediction models for patients with anal carcinoma receiving definitive chemoradiation: A population‑based study

Yinhang Wu, Xiaoyang Han, Yan Li, Kunli Zhu, Jinming Yu
Pages: 1443-1451
Published online on: 23 December 2019

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Article Open Access

Clinical characteristics of malignant melanoma in central China and predictors of metastasis

Ke Shi, Xuran Zhu, Zhongyang Liu, Nan Sun, Luosha Gu, Yang Wei, Xu Cheng, Zewei Zhang, Baihui Xie, Shuaixi Yang, Guangshuai Li, Linbo Liu
Pages: 1452-1464
Published online on: 16 December 2019

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Article Open Access

Long non‑coding RNA expression identified by microarray analysis: Candidate biomarkers in human acral lentiginous melanoma

Hao‑Ze Shi, Jing‑Shu Xiong, Cong‑Cong Xu, Wen‑Bo Bu, Yan Wang, Jian‑Fang Sun, Hao Chen
Pages: 1465-1477
Published online on: 11 December 2019

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Article Open Access

Tracking the important role of JUNB in hepatocellular carcinoma by single‑cell sequencing analysis

Peng Yan, Bin Zhou, Yingdong Ma, Ani Wang, Xiaojun Hu, Youli Luo, Yajun Yuan, Yajun Wei, Pengfei Pang, Junjie Mao
Pages: 1478-1486
Published online on: 20 December 2019

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Article Open Access

Immunohistochemical‑based molecular subtyping of colorectal carcinoma using maspin and markers of epithelial‑mesenchymal transition

Laura Banias, Ioan Jung, Tivadar Bara, Zsolt Fulop, Patricia Simu, Iunius Simu, Catalin Satala, Simona Gurzu
Pages: 1487-1495
Published online on: 18 December 2019

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Article Open Access

Prediction of overall survival time in patients with colon adenocarcinoma using DNA methylation profiling of long non‑coding RNAs

Qiongying Zhang, Zhuo Lin, Haiyan Zhang, Xiaodong Bao, Huxiang Zhang
Pages: 1496-1504
Published online on: 20 December 2019

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Article Open Access

lncRNA SNHG7 affects malignant tumor behaviors through downregulation of EZH2 in uveal melanoma cell lines

Xue Wu, Yiqun Yuan, Ruiqi Ma, Binbin Xu, Rui Zhang
Pages: 1505-1515
Published online on: 23 December 2019

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Article Open Access

Inhibition mechanism of lung cancer cell metastasis through targeted regulation of Smad3 by miR‑15a

Shuai Guo, Ming Li, Juan Li, Yan Lv
Pages: 1516-1522
Published online on: 10 December 2019

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Article Open Access

Expression of miR‑221 and miR‑489 in breast cancer patients and their relationship with prognosis

Fanfan Li
Pages: 1523-1529
Published online on: 10 December 2019

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Article Open Access

Influence mechanism of miRNA‑144 on proliferation and apoptosis of osteosarcoma cells

Xu Zhang, Zhengwei Li, Wei Ji, Xilong Chen, Qiang Gao, Dajin Li, Haihui Qin
Pages: 1530-1536
Published online on: 10 December 2019

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Article Open Access

Clinical significance of serum melatonin in predicting the severity of oral squamous cell carcinoma

Adina E. Stanciu, Adina Zamfir-Chiru-Anton, Marcel M. Stanciu, Anca Pantea Stoian, Viorel Jinga, Cornelia Nitipir, Alexandru Bucur, Teodora S. Pituru, Andreea L. Arsene, Cristina M. Dragoi, Razvan Hainarosie, Alina C. Nicolae, Mirela Gherghe, Dan C. Gheorghe, Demetrios A. Spandidos, Aristidis Tsatsakis, Maria Papasavva, Nikolaos Drakoulis
Pages: 1537-1543
Published online on: 13 December 2019

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Article Open Access

Intercellular adhesion molecule-1 and S-100β in sevoflurane combined with epidural anesthesia for radical resection of lung cancer

Nan Zhao, Chunyuan Lu, Liang Liu, Peng Sun, Jiange Han
Pages: 1544-1550
Published online on: 30 December 2019

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Article

Evaluation of circulating cell‑free DNA as a molecular monitoring tool in patients with metastatic cancer

Clemens Hufnagl, Michael Leisch, Lukas Weiss, Thomas Melchardt, Martin Moik, Daniela Asslaber, Geisberger Roland, Philipp Steininger, Thomas Meissnitzer, Daniel Neureiter, Richard Greil, Alexander Egle
Pages: 1551-1558
Published online on: 09 December 2019

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Article

Radiomics predicts survival of patients with advanced non‑small cell lung cancer undergoing PD‑1 blockade using Nivolumab

Valerio Nardone, Paolo Tini, Pierpaolo Pastina, Cirino Botta, Alfonso Reginelli, Salvatore Francesco Carbone, Rocco Giannicola, Grazia Calabrese, Carmela Tebala, Cesare Guida, Aldo Giudice, Vito Barbieri, Pierfrancesco Tassone, Pierosandro Tagliaferri, Salvatore Cappabianca, Rosanna Capasso, Amalia Luce, Michele Caraglia, Maria Antonietta Mazzei, Luigi Pirtoli, Pierpaolo Correale
Pages: 1559-1566
Published online on: 16 December 2019

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Article

miR‑519 regulates the proliferation of breast cancer cells via targeting human antigen R

Lili Ren, Yong Li, Qun Zhao, Liqiao Fan, Bibo Tan, Aimin Zang, Hua Yang
Pages: 1567-1576
Published online on: 20 December 2019

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Article

Nesfatin‑1 is a potential diagnostic biomarker for gastric cancer

Xiao‑Qing Wang, Yan Zheng, Pei‑Fei Fang, Xian‑Bing Song
Pages: 1577-1583
Published online on: 10 December 2019

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Article

High mobility group AT‑hook 2 and c‑MYC as potential prognostic factors in pancreatic ductal adenocarcinoma

Ke Li, Jiali Yang, Jiafei Chen, Yanshu Shi, Zhuoli Zhang, Wei Chen
Pages: 1584-1592
Published online on: 11 December 2019

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Article

Inhibition of acetylcholinesterase activity and β‑amyloid oligomer formation by 6‑bromotryptamine A, a multi‑target anti‑Alzheimer's molecule

Xiaofeng Jin, Minjun Wang, Jieyi Shentu, Chunhui Huang, Yujing Bai, Hanbo Pan, Difan Zhang, Zhijun Yuan, Hui Zhang, Xiao Xiao, Xiang Wu, Lijian Ding, Qinwen Wang, Shan He, Wei Cui
Pages: 1593-1601
Published online on: 18 December 2019

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Article Open Access

Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types

Yasunari Miyagi, Kazuhiro Takehara, Yoko Nagayasu, Takahito Miyake
Pages: 1602-1610
Published online on: 12 December 2019

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Upregulation of contactin‑1 expression promotes prostate cancer progression

Boren Wang, Xi Yang, Ting Zhao, Hanghang Du, Tong Wang, Suping Zhong, Bo Yang, Hui Li
Pages: 1611-1618
Published online on: 23 December 2019

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Analysis of circular RNA‑associated competing endogenous RNA network in breast cancer

Xuekang Wang, Yanhan Dong, Qiong Wu, Tong Lu, Yuanyong Wang, Wenchao Liu, Chengyu Liu, Wenhua Xu
Pages: 1619-1634
Published online on: 02 January 2020

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[Corrigendum] Long non-coding RNA transcribed from pseudogene PPIAP43 is associated with radiation sensitivity of small cell lung cancer cells

Shilong Wang, Jinming Yu
Pages: 1635-1635
Published online on: 10 December 2019

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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