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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2020 Volume 19 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Biology and pathogenesis of human osteosarcoma (Review)

Judson Welber Veríssimo de Azevedo, Thales Allyrio Araújo de Medeiros Fernandes, José Veríssimo Fernandes, Jenner Chrystian Veríssimo de Azevedo, Daniel Carlos Ferreira Lanza, Christiane Medeiros Bezerra, Vânia Sousa Andrade, Josélio Maria Galvão de Araújo, José Veríssimo Fernandes
Pages: 1099-1116
Published online on: 18 December 2019

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Article Open Access

Role of Gd2O3‑doped carbon‑11‑choline‑lenvatinib nanoparticles contrast agent PET/CT in the diagnosis of patients with lung cancer

Tong Zhou, Dongfang Hang, Ying Li, Jin Zhang, Huayang Wu, Hongyan Wang, Enbing Tian, Jun Yan
Pages: 1117-1124
Published online on: 23 December 2019

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Article Open Access

Molecular cytogenetic pilot study on pleomorphic adenomas of salivary glands

Jovanna Thielker, Anja Weise, Moneeb A.K. Othman, Isabel M. Carreria, Joana B. Melo, Ferdinand von Eggeling, Orlando Guntinas‑Lichius, Monika Ziegler, Thomas Liehr
Pages: 1125-1130
Published online on: 10 December 2019

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Article Open Access

Long non‑coding RNA mortal obligate RNA transcript inhibits the migration and invasion of colon cancer cells by inactivating transforming growth factor β1

Taicheng Zhou, Lili Wu, Zhen Zong, Ning Ma, Yingru Li, Zhipeng Jiang, Qirui Wang, Shuang Chen
Pages: 1131-1136
Published online on: 09 December 2019

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Article Open Access

Targeted molecular profiling of genetic alterations in colorectal cancer using next‑generation sequencing

Jia Luo, Shengjun Zhang, Meihua Tan, Jia Li, Huadong Xu, Yanfei Tan, Yue Huang
Pages: 1137-1144
Published online on: 10 December 2019

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Article Open Access

Downregulation of long non‑coding RNA NR2F2‑AS1 inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells by upregulating the expression of PTEN

He Qin, Chong Qin
Pages: 1145-1150
Published online on: 12 December 2019

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Article Open Access

Effect of dexmedetomidine on the cognitive function of patients undergoing gastric cancer surgery by regulating the PI3K/AKT signaling pathway

Zhiyuan Wang, Zijin Shen, Haibin Wang, Lin Zhang, Rong Dong
Pages: 1151-1156
Published online on: 18 December 2019

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Article Open Access

Downregulation of LINC01140 is associated with adverse features of breast cancer

Deheng Li, Liangdong Li, Yiqun Cao, Xin Chen
Pages: 1157-1164
Published online on: 25 November 2019

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Article Open Access

Diagnostic accuracy of urinary survivin mRNA expression detected by RT‑PCR compared with urine cytology in the detection of bladder cancer: A meta‑analysis of diagnostic test accuracy in head‑to‑head studies

Liang Fu, Jiwang Zhang, Ling Li, Yuxing Yang, Yongqiang Yuan
Pages: 1165-1174
Published online on: 18 December 2019

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Article Open Access

Time‑series clustering of cytokine expression after transarterial chemoembolization in patients with hepatocellular carcinoma

Feng Qi, Lingxiao Wang, Peixin Huang, Zhiying Zhao, Biwei Yang, Jinglin Xia
Pages: 1175-1186
Published online on: 11 December 2019

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Article Open Access

Effects of propofol and sevoflurane on blood glucose, hemodynamics, and inflammatory factors of patients with type 2 diabetes mellitus and gastric cancer

Jinhui Liu, Li Yang
Pages: 1187-1194
Published online on: 10 December 2019

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Article Open Access

Effects of miR‑129‑3p on biological functions of prostate cancer cells through targeted regulation of Smad3

Yunpeng Jia, Yu Gao, Jianguo Dou
Pages: 1195-1202
Published online on: 13 December 2019

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Article Open Access

Effects of hub genes on the clinicopathological and prognostic features of lung adenocarcinoma

Dong‑Hu Yu, Jing‑Yu Huang, Xiao‑Ping Liu, Xiao‑Lan Ruan, Chen Chen, Wei‑Dong Hu, Sheng Li
Pages: 1203-1214
Published online on: 09 December 2019

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Article Open Access

Identification of osteosarcoma driver genes using a network method

Zebing Si , Konghe Hu
Pages: 1215-1222
Published online on: 12 December 2019

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Article Open Access

PD‑L1 gene promoter methylation represents a potential diagnostic marker in advanced gastric cancer

Dan Lv, Chengjuan Xing, Lin Cao, Yuejian Zhuo, Tao Wu, Na Gao
Pages: 1223-1234
Published online on: 16 December 2019

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Article Open Access

Prognostic significance of peritumoral fibrosis after resection of pancreatic head cancer

Peng Chen, Youmei Wang, Xiaosan Fang, Xiaoming Wang, Guannan Wang
Pages: 1235-1240
Published online on: 04 December 2019

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Article Open Access

Expression levels of ARHI and Beclin1 in thyroid cancer and their relationship with clinical pathology and prognosis

Houwei Zhu, Yanqing Qu
Pages: 1241-1246
Published online on: 17 December 2019

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Article Open Access

BMP4 induces asymmetric cell division in human glioma stem-like cells

Motofumi Koguchi, Yukiko Nakahara, Hiroshi Ito, Tomihiro Wakamiya, Fumitaka Yoshioka, Atsushi Ogata, Kohei Inoue, Jun Masuoka, Hideki Izumi, Tatsuya Abe
Pages: 1247-1254
Published online on: 20 December 2019

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Article Open Access

Long non‑coding RNA TTN‑AS1 promotes breast cancer cell migration and invasion via sponging miR‑140‑5p Retraction in /10.3892/ol.2020.12018

Jie Xue, Zhixia Zhang, Xiaona Li, Qingfang Ren, Qinghua Wang
Pages: 1255-1260
Published online on: 17 December 2019

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Article Open Access

Regulation of lncRNA PVT1 on miR-125 in metastasis of gastric cancer cells Retraction in /10.3892/ol.2025.15209

Jiatai Niu, Xiangxin Song, Xiaomei Zhang
Pages: 1261-1266
Published online on: 10 December 2019

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Article Open Access

lncRNA PVT1 accelerates progression of non‑small cell lung cancer via targeting miRNA‑526b/EZH2 regulatory loop

Chun Qiu, Sai Li, Datong Sun, Shenghui Yang
Pages: 1267-1272
Published online on: 20 December 2019

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Article Open Access

Expression of miR‑34a and Ki67 in nasopharyngeal carcinoma and the relationship with clinicopathological features and prognosis

Linqi Wei, Chao Shi, Yonghong Zhang
Pages: 1273-1280
Published online on: 13 December 2019

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Article Open Access

Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer

Yakun Hu, Yuchen Yan, Yang Xu, He Yang, Lisha Fang, Yongli Liu, Xin Li, Qiang Li, Hongchao Yan
Pages: 1281-1290
Published online on: 12 December 2019

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Article Open Access

Bone morphogenic proteins‑2, ‑4, ‑6 and 7 in non‑muscle invasive bladder cancer

Tvrtko Hudolin, Zeljko Kastelan, Ahmad El‑Saleh, Mirko Bakula, Marijana Coric, Petar Kes, Davor Tomas, Nikolina Basic‑Jukic
Pages: 1291-1297
Published online on: 13 December 2019

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Article Open Access

Involvement of the TGF-β1 pathway in caveolin-1-associated regulation of head and neck tumor cell metastasis

Jinjie Sun, Yongtian Lu, Changyun Yu, Ting Xu, Guohui Nie, Beiping Miao, Xin Zhang
Pages: 1298-1304
Published online on: 06 December 2019

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Article Open Access

mi‑R4435‑2HG promotes proliferation and inhibits apoptosis of cancer cells in ovarian carcinoma by upregulating ROCK2

Jinghui Hu, Li Wang, Wei Zhao, Yujie Huang, Zhe Wang, Heping Shen
Pages: 1305-1309
Published online on: 11 December 2019

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Article Open Access

Influence of miR‑101 on proliferation of liver cancer cells through the MAPK/ERK signaling pathway

Xuan Meng, Yong Shi, Xin Xiang, Chonghui Li, Xinlan Ge, Ke Pan, Yurong Liang
Pages: 1310-1316
Published online on: 12 December 2019

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Article Open Access

Evaluation of azacitidine in patients with transplant‑ineligible myelodysplastic syndromes and acute myeloid leukemia with myelodysplasia‑related changes in a Japanese clinical setting

Aya Nakaya, Shinya Fujita, Atsushi Satake, Takahisa Nakanishi, Yoshiko Azuma, Yukie Tsubokura, Ryo Saito, Akiko Konishi, Masaaki Hotta, Hideaki Yoshimura, Kazuyoshi Ishii, Tomoki Ito, Shosaku Nomura
Pages: 1317-1321
Published online on: 18 December 2019

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Article Open Access

IDH1‑R132H mutation radiosensitizes U87MG glioma cells via epigenetic downregulation of TIGAR

Narui Yin, Ting Xie, Haowen Zhang, Jian Chen, Jiahua Yu, Fenju Liu
Pages: 1322-1330
Published online on: 25 November 2019

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Article Open Access

Evaluation of heavy metals and metabolites in the urine of patients with breast cancer

Yuhao Men, Ling Li, Fen Zhang, Xueyuan Kong, Weidong Zhang, Chongli Hao, Guotian Wang
Pages: 1331-1337
Published online on: 11 December 2019

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Article Open Access

Glucose restriction combined with chemotherapy decreases telomere length and cancer antigen‑125 secretion in ovarian carcinoma

Stephanie Antoun, David Atallah, Roula Tahtouh, Mona Diab Assaf, Malak Moubarak, Eliane Nasser Ayoub, Georges Chahine, George Hilal
Pages: 1338-1350
Published online on: 20 December 2019

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Article Open Access

A novel risk score model for stomach adenocarcinoma based on the expression levels of 10 genes

Encui Guan, Feng Tian, Zhaoxia Liu
Pages: 1351-1367
Published online on: 09 December 2019

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Article Open Access

Centromere protein F and Forkhead box M1 correlation with prognosis of non‑small cell lung cancer

Rui Li, Xia Wang, Xiaoqian Zhao, Xiaohong Zhang, Honghai Chen, Yue Ma, Yandong Liu
Pages: 1368-1374
Published online on: 20 December 2019

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Article Open Access

Integrated bioinformatics analysis to screen hub genes in the lymph node metastasis of thyroid cancer

Si Lu, Rongjie Zhao, Jie Shen, Yu Zhang, Jingjing Shi, Chenke Xu, Jiali Chen, Renbin Lin, Weidong Han, Dingcun Luo
Pages: 1375-1383
Published online on: 06 December 2019

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Article Open Access

A natural compound obtained from Valeriana jatamansi selectively inhibits glioma stem cells

Shi‑Gang Qi, Li‑Qiu Quan, Xiao‑Yue Cui, Hong‑Mei Li, Xu‑Dong Zhao, Rong‑Tao Li
Pages: 1384-1392
Published online on: 23 December 2019

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Article Open Access

Cardamonin as a potential treatment for melanoma induces human melanoma cell apoptosis

Yuyang Yue, Lijuan Liu, Peipei Liu, Yuting Li, Haitao Lu, Yanjia Li, Guoqiang Zhang, Xinsuo Duan
Pages: 1393-1399
Published online on: 23 December 2019

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Article Open Access

TRIM59 as a novel molecular biomarker to predict the prognosis of patients with NSCLC

Ming Lou, Zhaojia Gao, Tao Zhu, Xiaoliang Mao, Yeming Wang, Kai Yuan, Jichun Tong
Pages: 1400-1408
Published online on: 10 December 2019

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Article Open Access

Targeting of TLE3 by miR‑3677 in human breast cancer promotes cell proliferation, migration and invasion Retraction in /10.3892/ol.2024.14840

Li‑Na Peng, Xing‑Yan Deng, Xiao‑Xiong Gan, Jin‑Hui Zhang, Guang‑Hui Ren, Fei Shen, Jian‑Hua Feng, Wen‑Song Cai, Bo Xu
Pages: 1409-1417
Published online on: 23 December 2019

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Article Open Access

MicroRNA‑608 promotes apoptosis via BRD4 downregulation in pancreatic ductal adenocarcinoma

Maoyuan Li, Ting Li, Weidong Ma, Xiuchao Wang, Gang Zhao
Pages: 1418-1426
Published online on: 31 December 2019

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Article Open Access

MicroRNA‑519 inhibits hypoxia‑induced tumorigenesis of pancreatic cancer by regulating immune checkpoint PD‑L1

Kate Nong, Dong Zhang, Changze Chen, Yue Yang, Yong Yang, Shengyong Liu, Huihua Cai
Pages: 1427-1433
Published online on: 20 December 2019

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Article Open Access

Bioinformatics analysis of esophageal cancer unveils an integrated mRNA‑lncRNA signature for predicting prognosis

Tian Lan, Zunqiang Xiao, Hua Luo, Kunlun Su, Ouou Yang, Chengni Zhan, Yunyan Lu
Pages: 1434-1442
Published online on: 11 December 2019

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Article Open Access

Survival prediction models for patients with anal carcinoma receiving definitive chemoradiation: A population‑based study

Yinhang Wu, Xiaoyang Han, Yan Li, Kunli Zhu, Jinming Yu
Pages: 1443-1451
Published online on: 23 December 2019

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Article Open Access

Clinical characteristics of malignant melanoma in central China and predictors of metastasis

Ke Shi, Xuran Zhu, Zhongyang Liu, Nan Sun, Luosha Gu, Yang Wei, Xu Cheng, Zewei Zhang, Baihui Xie, Shuaixi Yang, Guangshuai Li, Linbo Liu
Pages: 1452-1464
Published online on: 16 December 2019

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Article Open Access

Long non‑coding RNA expression identified by microarray analysis: Candidate biomarkers in human acral lentiginous melanoma

Hao‑Ze Shi, Jing‑Shu Xiong, Cong‑Cong Xu, Wen‑Bo Bu, Yan Wang, Jian‑Fang Sun, Hao Chen
Pages: 1465-1477
Published online on: 11 December 2019

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Article Open Access

Tracking the important role of JUNB in hepatocellular carcinoma by single‑cell sequencing analysis

Peng Yan, Bin Zhou, Yingdong Ma, Ani Wang, Xiaojun Hu, Youli Luo, Yajun Yuan, Yajun Wei, Pengfei Pang, Junjie Mao
Pages: 1478-1486
Published online on: 20 December 2019

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Article Open Access

Immunohistochemical‑based molecular subtyping of colorectal carcinoma using maspin and markers of epithelial‑mesenchymal transition

Laura Banias, Ioan Jung, Tivadar Bara, Zsolt Fulop, Patricia Simu, Iunius Simu, Catalin Satala, Simona Gurzu
Pages: 1487-1495
Published online on: 18 December 2019

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Article Open Access

Prediction of overall survival time in patients with colon adenocarcinoma using DNA methylation profiling of long non‑coding RNAs

Qiongying Zhang, Zhuo Lin, Haiyan Zhang, Xiaodong Bao, Huxiang Zhang
Pages: 1496-1504
Published online on: 20 December 2019

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Article Open Access

lncRNA SNHG7 affects malignant tumor behaviors through downregulation of EZH2 in uveal melanoma cell lines

Xue Wu, Yiqun Yuan, Ruiqi Ma, Binbin Xu, Rui Zhang
Pages: 1505-1515
Published online on: 23 December 2019

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Article Open Access

Inhibition mechanism of lung cancer cell metastasis through targeted regulation of Smad3 by miR‑15a

Shuai Guo, Ming Li, Juan Li, Yan Lv
Pages: 1516-1522
Published online on: 10 December 2019

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Article Open Access

Expression of miR‑221 and miR‑489 in breast cancer patients and their relationship with prognosis

Fanfan Li
Pages: 1523-1529
Published online on: 10 December 2019

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Article Open Access

Influence mechanism of miRNA‑144 on proliferation and apoptosis of osteosarcoma cells

Xu Zhang, Zhengwei Li, Wei Ji, Xilong Chen, Qiang Gao, Dajin Li, Haihui Qin
Pages: 1530-1536
Published online on: 10 December 2019

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Article Open Access

Clinical significance of serum melatonin in predicting the severity of oral squamous cell carcinoma

Adina E. Stanciu, Adina Zamfir-Chiru-Anton, Marcel M. Stanciu, Anca Pantea Stoian, Viorel Jinga, Cornelia Nitipir, Alexandru Bucur, Teodora S. Pituru, Andreea L. Arsene, Cristina M. Dragoi, Razvan Hainarosie, Alina C. Nicolae, Mirela Gherghe, Dan C. Gheorghe, Demetrios A. Spandidos, Aristidis Tsatsakis, Maria Papasavva, Nikolaos Drakoulis
Pages: 1537-1543
Published online on: 13 December 2019

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Article Open Access

Intercellular adhesion molecule-1 and S-100β in sevoflurane combined with epidural anesthesia for radical resection of lung cancer

Nan Zhao, Chunyuan Lu, Liang Liu, Peng Sun, Jiange Han
Pages: 1544-1550
Published online on: 30 December 2019

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Article

Evaluation of circulating cell‑free DNA as a molecular monitoring tool in patients with metastatic cancer

Clemens Hufnagl, Michael Leisch, Lukas Weiss, Thomas Melchardt, Martin Moik, Daniela Asslaber, Geisberger Roland, Philipp Steininger, Thomas Meissnitzer, Daniel Neureiter, Richard Greil, Alexander Egle
Pages: 1551-1558
Published online on: 09 December 2019

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Article

Radiomics predicts survival of patients with advanced non‑small cell lung cancer undergoing PD‑1 blockade using Nivolumab

Valerio Nardone, Paolo Tini, Pierpaolo Pastina, Cirino Botta, Alfonso Reginelli, Salvatore Francesco Carbone, Rocco Giannicola, Grazia Calabrese, Carmela Tebala, Cesare Guida, Aldo Giudice, Vito Barbieri, Pierfrancesco Tassone, Pierosandro Tagliaferri, Salvatore Cappabianca, Rosanna Capasso, Amalia Luce, Michele Caraglia, Maria Antonietta Mazzei, Luigi Pirtoli, Pierpaolo Correale
Pages: 1559-1566
Published online on: 16 December 2019

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Article

miR‑519 regulates the proliferation of breast cancer cells via targeting human antigen R

Lili Ren, Yong Li, Qun Zhao, Liqiao Fan, Bibo Tan, Aimin Zang, Hua Yang
Pages: 1567-1576
Published online on: 20 December 2019

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Article

Nesfatin‑1 is a potential diagnostic biomarker for gastric cancer

Xiao‑Qing Wang, Yan Zheng, Pei‑Fei Fang, Xian‑Bing Song
Pages: 1577-1583
Published online on: 10 December 2019

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Article

High mobility group AT‑hook 2 and c‑MYC as potential prognostic factors in pancreatic ductal adenocarcinoma

Ke Li, Jiali Yang, Jiafei Chen, Yanshu Shi, Zhuoli Zhang, Wei Chen
Pages: 1584-1592
Published online on: 11 December 2019

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Article

Inhibition of acetylcholinesterase activity and β‑amyloid oligomer formation by 6‑bromotryptamine A, a multi‑target anti‑Alzheimer's molecule

Xiaofeng Jin, Minjun Wang, Jieyi Shentu, Chunhui Huang, Yujing Bai, Hanbo Pan, Difan Zhang, Zhijun Yuan, Hui Zhang, Xiao Xiao, Xiang Wu, Lijian Ding, Qinwen Wang, Shan He, Wei Cui
Pages: 1593-1601
Published online on: 18 December 2019

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Article Open Access

Application of deep learning to the classification of uterine cervical squamous epithelial lesion from colposcopy images combined with HPV types

Yasunari Miyagi, Kazuhiro Takehara, Yoko Nagayasu, Takahito Miyake
Pages: 1602-1610
Published online on: 12 December 2019

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Upregulation of contactin‑1 expression promotes prostate cancer progression

Boren Wang, Xi Yang, Ting Zhao, Hanghang Du, Tong Wang, Suping Zhong, Bo Yang, Hui Li
Pages: 1611-1618
Published online on: 23 December 2019

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Analysis of circular RNA‑associated competing endogenous RNA network in breast cancer

Xuekang Wang, Yanhan Dong, Qiong Wu, Tong Lu, Yuanyong Wang, Wenchao Liu, Chengyu Liu, Wenhua Xu
Pages: 1619-1634
Published online on: 02 January 2020

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Correction Open Access

[Corrigendum] Long non-coding RNA transcribed from pseudogene PPIAP43 is associated with radiation sensitivity of small cell lung cancer cells

Shilong Wang, Jinming Yu
Pages: 1635-1635
Published online on: 10 December 2019

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May-2026 Volume 31 Issue 5

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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