Open Access

PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy

  • Authors:
    • Xun Zhao
    • Zhuo Liu
    • Hongxian Zhang
    • Liwei Li
    • Shiying Tang
    • Guoliang Wang
    • Shudong Zhang
    • Shumin Wang
    • Xiaojun Tian
    • Lulin Ma
  • View Affiliations

  • Published online on: April 23, 2020     https://doi.org/10.3892/ol.2020.11571
  • Pages: 201-208
  • Copyright: © Zhao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

The present study aimed to develop an accurate preoperative scoring system to predict the probability of using laparoscopic surgery in radical nephrectomy and thrombectomy. The clinical data of 123 patients with renal cell carcinoma with renal vein or inferior vena cava tumour thrombus admitted to the Department of Urology at Peking University Third Hospital between January 2015 and May 2018 were retrospectively analysed. Univariate and multivariate regression analyses were used to create the scoring system with an emphasis on the area improvement under the receiver operating characteristic curve. A total of 58 (47.2%) patients underwent complete laparoscopic surgery, 56 (45.5%) underwent complete open surgery and 9 (7.3%) underwent laparoscopic conversion to open surgery. The final multivariable model included the following three factors: Clinical node stage (P=0.030), Mayo classification (P<0.001) and tumour diameter (P=0.001). These three variables were then used to construct the score system named Peking University Third Hospital Laparoscopic Probability (PKUTHLP), which ranges from 0‑5. The proportion of patients undergoing laparoscopic surgery for each level of the PKUTHLP score were as follows: 0 (n=20), 100%; 1 (n=34), 67.6%; 2 (n=21), 33.3%; 3 (n=21), 19.0%; 4 (n=23), 17.4%; and 5 (n=4), 0.0%. Overall, the PKUTHLP score accurately predicted the probability of using laparoscopic surgery in radical nephrectomy and thrombectomy; however, prospective validation of the PKUTHLP scoring system is required.

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July 2020
Volume 20 Issue 1

Print ISSN: 1792-1074
Online ISSN:1792-1082

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APA
Zhao, X., Liu, Z., Zhang, H., Li, L., Tang, S., Wang, G. ... Ma, L. (2020). PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy. Oncology Letters, 20, 201-208. https://doi.org/10.3892/ol.2020.11571
MLA
Zhao, X., Liu, Z., Zhang, H., Li, L., Tang, S., Wang, G., Zhang, S., Wang, S., Tian, X., Ma, L."PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy". Oncology Letters 20.1 (2020): 201-208.
Chicago
Zhao, X., Liu, Z., Zhang, H., Li, L., Tang, S., Wang, G., Zhang, S., Wang, S., Tian, X., Ma, L."PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy". Oncology Letters 20, no. 1 (2020): 201-208. https://doi.org/10.3892/ol.2020.11571