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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 20 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Novel prognostic molecular markers in lung cancer (Review)

Michał Puderecki, Justyna Szumiło, Barbara Marzec‑Kotarska
Pages: 9-18
Published online on: 15 April 2020

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Review Open Access

Endocrine disruptors from the environment affecting breast cancer (Review)

Gloria M. Calaf, Richard Ponce‑Cusi, Francisco Aguayo, Juan P. Muñoz, Tammy C. Bleak
Pages: 19-32
Published online on: 22 April 2020

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Article Open Access

Visceral obesity and cell cycle pathways serve as links in the association between bisphenol A exposure and breast cancer

Tsu‑Nai Wang, Pei‑Jing Yang, Yu‑Ting Tseng, Yi‑Shan Tsai, Po‑Lin Kuo, Chien‑Chih Chiu, Shih‑Shin Liang, Tsung‑Hua Hsieh, Ming‑Feng Hou, Eing‑Mei Tsai
Pages: 33-42
Published online on: 21 April 2020

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Article Open Access

YRDC is upregulated in non‑small cell lung cancer and promotes cell proliferation by decreasing cell apoptosis

Haibo Shen, Enkuo Zheng, Zhenhua Yang, Minglei Yang, Xiang Xu, Yinjie Zhou, Junjun Ni, Rui Li, Guofang Zhao
Pages: 43-52
Published online on: 21 April 2020

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Article Open Access

Chloroquine increases the anti‑cancer activity of epirubicin in A549 lung cancer cells

Ai‑Ling Liang, Jing Zhang, Shen‑Lin Du, Bin Zhang, Xuan Ma, Cui‑Yun Wu, Yong‑Jun Liu
Pages: 53-60
Published online on: 22 April 2020

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Article Open Access

AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K

Shujuan Tong, Tao Zhou, Yufen Meng, Dongqin Xu, Jianping Chen
Pages: 61-66
Published online on: 21 April 2020

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Article Open Access

Ubiquitin‑specific peptidase 17 promotes cisplatin resistance via PI3K/AKT activation in non‑small cell lung cancer

Shengchao Zhang, Zhenglang Xu, Jun Yuan, Hao Chen
Pages: 67-74
Published online on: 23 April 2020

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Article Open Access

Integrative transcriptome analysis identified a BMP signaling pathway‑regulated lncRNA AC068643.1 in IDH mutant and wild‑type glioblastomas

Guo‑Hao Huang, Yu‑Chun Pei, Lin Yang, Ke‑Jie Mou, Jun‑Hai Tang, Yan Xiang, Jun Liu, Sheng‑Qing Lv
Pages: 75-84
Published online on: 15 April 2020

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Article Open Access

Prognostic prediction of a 12‑methylation gene‑based risk score system on pancreatic adenocarcinoma

Daoqin Dou, Shaohua Yang, Jiren Zhang
Pages: 85-98
Published online on: 27 April 2020

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Article Open Access

Metastasis‑associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c‑Jun/MMPs pathway

Zexin Su, Bingsheng Yang, Zhirui Zeng, Shuang Zhu, Chenyang Wang, Shan Lei, Yongfa Jiang, Lijun Lin
Pages: 99-112
Published online on: 15 April 2020

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Article Open Access

Bioinformatics analysis of prognosis-related long non-coding RNAs in invasive breast carcinoma

Yuanyuan Hu, Xidong Gu, Yin Duan, Yong Shen, Xiaohong Xie
Pages: 113-122
Published online on: 21 April 2020

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Article Open Access

Application of the chemokine‑chemokine receptor axis increases the tumor‑targeted migration ability of cytokine‑induced killer cells in patients with colorectal cancer

Yunlian Zou, Jianhua Liang, Danyang Li, Jingjing Fang, Linping Wang, Jinli Wang, Jinping Zhang, Qiang Guo, Xinmin Yan, Hui Tang
Pages: 123-134
Published online on: 15 April 2020

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Article Open Access

Pathological roles of c‑Met in bladder cancer: Association with cyclooxygenase‑2, heme oxygenase‑1, vascular endothelial growth factor‑A and programmed death ligand 1

Yuta Mukae, Yasuyoshi Miyata, Yuichiro Nakamura, Kyohei Araki, Asato Otsubo, Tsutomu Yuno, Kensuke Mitsunari, Tomohiro Matsuo, Kojiro Ohba, Hideki Sakai
Pages: 135-144
Published online on: 15 April 2020

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Article Open Access

Distinct characteristics of dasatinib‑induced pyroptosis in gasdermin E‑expressing human lung cancer A549 cells and neuroblastoma SH‑SY5Y cells

Juan Zhang, Yang Chen, Qiyang He
Pages: 145-154
Published online on: 21 April 2020

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Article Open Access

Hypermethylation of tumor necrosis factor decoy receptor gene in non‑small cell lung cancer

Yuanlin Qi, Lin Qi, Minglian Qiu, Caiyun Yao, Mingfang Zhang, Jianbo Lin, Zhonghua Zheng, Chujia Chen, Hongxiang Li, Shiwei Duan
Pages: 155-164
Published online on: 22 April 2020

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Article Open Access

Downregulation of GNA14 in hepatocellular carcinoma indicates an unfavorable prognosis

Tao Yu, Siyu Lu, Wenjing Xie
Pages: 165-172
Published online on: 15 April 2020

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Article Open Access

MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA‑194

Hongming Wang, Fei Wang, Wenyu Ouyang, Xuejun Jiang, Wei Li
Pages: 173-182
Published online on: 21 April 2020

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Article Open Access

Efficacy and safety of CT‑guided 125I brachytherapy in elderly patients with non‑small cell lung cancer

Jing Zhao, Zheng Zhi, Hongtao Zhang, Jinxin Zhao, Yan Di, Ke Xu, Chunling Ma, Zezhou Liu, Aixia Sui, Juan Wang
Pages: 183-192
Published online on: 21 April 2020

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Article Open Access

Leveraging methylation to identify the potential causal genes associated with survival in lung adenocarcinoma and lung squamous cell carcinoma

Lu Liu, Ping Zeng, Sheng Yang, Zhongshang Yuan
Pages: 193-200
Published online on: 22 April 2020

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Article Open Access

PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy

Xun Zhao, Zhuo Liu, Hongxian Zhang, Liwei Li, Shiying Tang, Guoliang Wang, Shudong Zhang, Shumin Wang, Xiaojun Tian, Lulin Ma
Pages: 201-208
Published online on: 23 April 2020

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Case Report Open Access

Epidural angiolipoma with concomitant intradural extramedullary capillary hemangioma at the same spinal level: A case report

Yongquan Cheng, Kaiwu Lu, Hui Jiang
Pages: 209-214
Published online on: 21 April 2020

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Article Open Access

Identification of genes associated with gastric cancer survival and construction of a nomogram to improve risk stratification for patients with gastric cancer

Yongfeng Ding, Yanyan Chen, Mengjie Wu, Linrong Li, Yingying Huang, Haiyong Wang, Haohao Wang, Xiongfei Yu, Nong Xu, Lisong Teng
Pages: 215-225
Published online on: 15 April 2020

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Article Open Access

Expression and regulation effects of chemokine receptor 7 in colon cancer cells

Xiang Li, Xuemei Wang, Zitao Li, Yanjun Liu, Liang Sang, Zhen Zhang, Yixia Zhang
Pages: 226-234
Published online on: 21 April 2020

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Article Open Access

lncRNA‑CD160 decreases the immunity of CD8+ T cells through epigenetic mechanisms in hepatitis B virus infection Retraction in /10.3892/ol.2025.15075

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Pages: 235-247
Published online on: 15 April 2020

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Article Open Access

STAT1 is a modulator of the expression of frequently rearranged in advanced T‑cell lymphomas 1 expression in U251 cells

Geng Guo, Shule Wang, Yining Hao, Yeqing Ren, Yongqiang Wu, Jianping Zhang, Dong Liu
Pages: 248-256
Published online on: 21 April 2020

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Article Open Access

P4HB modulates epithelial‑mesenchymal transition and the β‑catenin/Snail pathway influencing chemoresistance in liver cancer cells

Xing Ma, Jiening Wang, Juhua Zhuang, Xiaokun Ma, Ni Zheng, Yanan Song, Wei Xia
Pages: 257-265
Published online on: 23 April 2020

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Article Open Access

Hsa_circ_0038646 promotes cell proliferation and migration in colorectal cancer via miR‑331‑3p/GRIK3

Haipeng Du, Zhiguo He, Fumei Feng, Daming Chen, Lei Zhang, Jingzhen Bai, Huiguo Wu, Enkun Han, Jiansheng Zhang
Pages: 266-274
Published online on: 21 April 2020

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Article Open Access

Distinct diagnostic and prognostic values of γ‑aminobutyric acid type A receptor family genes in patients with colon adenocarcinoma

Ling Yan, Yi‑Zhen Gong, Meng‑Nan Shao, Guo‑Tian Ruan, Hai‑Lun Xie, Xi‑Wen Liao, Xiang‑Kun Wang, Quan‑Fa Han, Xin Zhou, Li‑Cheng Zhu, Feng Gao, Jia‑Liang Gan
Pages: 275-291
Published online on: 24 April 2020

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Article Open Access

Vitamin D3 mediates miR‑15a‑5p inhibition of liver cancer cell proliferation via targeting E2F3

Yulong Li, Qiang Lin, Su'e Chang, Rong Zhang, Jingjie Wang
Pages: 292-298
Published online on: 24 April 2020

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Article Open Access

miR‑208b‑5p inhibits invasion of non‑small cell lung cancer through the STAT3 pathway by targeting interleukin‑9

Jun Ma, Hong‑Feng Tong, Jie‑Huan Lin, Fu‑Nan Chen, Can‑Xing Wu, Cheng‑Zhang Cao, Jian Wu, Shu‑Qiao Hu
Pages: 299-307
Published online on: 23 April 2020

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Article Open Access

Prognostic and predictive value of immune/stromal-related gene biomarkers in renal cell carcinoma

Sen Wang, Xiangguang Zheng, Xinglu Chen, Xiaojun Shi, Sansan Chen
Pages: 308-316
Published online on: 24 April 2020

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Article Open Access

Significant diagnostic value of circulating tumour cells in colorectal cancer

Haijiao Yu, Ling Ma, Yubing Zhu, Wenxia Li, Lei Ding, Hong Gao
Pages: 317-325
Published online on: 15 April 2020

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Article Open Access

Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma

Wen‑Wen Lin, Guan‑Yong Ou, Jia‑Zhe Lin, San‑Jun Yi, Wei‑Cheng Yao, Hong‑Chao Pan, Wei‑Jiang Zhao
Pages: 326-336
Published online on: 21 April 2020

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Article Open Access

Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β‑catenin signaling pathway in colon cancer

Jiayu Mao, Xueqi Chen, Chunsaier Wang, Wenbin Li, Jingnan Li
Pages: 337-345
Published online on: 16 April 2020

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Article Open Access

Combination treatment of gemcitabine and sorafenib exerts a synergistic inhibitory effect on non‑small cell lung cancer in vitro and in vivo via the epithelial‑to‑mesenchymal transition process

Shanshan Jiang, Rong Wang, Xuan Zhang, Feihua Wu, Shengnan Li, Yongfang Yuan
Pages: 346-356
Published online on: 15 April 2020

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Article Open Access

Inhibitory effect of dihydromyricetin on the proliferation of JAR cells and its mechanism of action

Yanzhen Zuo, Yanjie Lu, Qian Xu, Dayong Sun, Xiujun Liang, Xiaoru Li, Yuhong Li
Pages: 357-363
Published online on: 16 April 2020

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Article Open Access

Serum concentration of sex hormone‑binding globulin in healthy volunteers and patients with breast cancer stratified by sex and age

Se Jung Park, Tae Soo Kim, Kyu Hyun Park, Woo Sun Kwon, Jin Ju Kim
Pages: 364-372
Published online on: 21 April 2020

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Article Open Access

Claudin 10 acts as a novel biomarker for the prognosis of patients with ovarian cancer

Zhongjun Li, Wenting Xuan, Lishan Huang, Niankun Chen, Zhiyong Hou, Biyan Lu, Chuangyu Wen, Suran Huang
Pages: 373-381
Published online on: 21 April 2020

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Article Open Access

Comprehensive characterization of driver genes in diffuse large B cell lymphoma

Zheng Fan, Renzhi Pei, Keya Sha, Lieguang Chen, Tiantian Wang, Ying Lu
Pages: 382-390
Published online on: 21 April 2020

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Article

The effect of TKI therapy and chemotherapy treatment delivery sequence on total progression‑free survival in patients with advanced EGFR‑mutated NSCLC

Jie Han, Yan Xu, Yumei Zhou, Aiju Yang, Jianfeng Cui, Pengxiang Chen, Hongyu Zhao, Xingqin Zhou, Chaoyan Shen, Jinming Yu, Heng Lu
Pages: 391-400
Published online on: 15 April 2020

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Article

Ensemble classification for predicting the malignancy level of pulmonary nodules on chest computed tomography images

Ning Xiao, Yan Qiang, Muhammad Bilal Zia, Sanhu Wang, Jianhong Lian
Pages: 401-408
Published online on: 27 April 2020

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Article Open Access

Role of lymph node dissection in radical cystectomy

Keyi Wang, Heng Shi, Weipu Mao, Lei Yin, Guangchun Wang, Donglai Fan, Jinbo Xie, Weiyi Li, Bo Peng
Pages: 409-419
Published online on: 21 April 2020

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Article

Chemoresistance‑associated alternative splicing signatures in serous ovarian cancer

Tianshui Sun, Qing Yang
Pages: 420-430
Published online on: 21 April 2020

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Review Open Access

Oncology during the COVID‑19 pandemic: challenges, dilemmas and the psychosocial impact on cancer patients (Review)

Konstantinos Tsamakis, Maria Gavriatopoulou, Dimitrios Schizas, Athina Stravodimou, Aikaterini Mougkou, Dimitrios Tsiptsios, Vasileios Sioulas, Eleftherios Spartalis, Athanasios D. Sioulas, Charalampos Tsamakis, Nikolaos Charalampakis, Christoph Mueller, Donna Arya, Paul Zarogoulidis, Demetrios A. Spandidos, Meletios A. Dimopoulos, Charalabos Papageorgiou, Emmanouil Rizos
Pages: 441-447
Published online on: 08 May 2020

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Review Open Access

Pathogenesis of pediatric B‑cell acute lymphoblastic leukemia: Molecular pathways and disease treatments (Review)

Fang‑Liang Huang, En‑Chih Liao, Chia‑Ling Li, Chung‑Yang Yen, Sheng‑Jie Yu
Pages: 448-454
Published online on: 04 May 2020

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Review Open Access

Signal transducer and activator of transcription 6 as a target in colon cancer therapy (Review)

Yael Delgado‑Ramirez, Vaneesa Colly, Giovanni Villanueva Gonzalez, Sonia Leon‑Cabrera
Pages: 455-464
Published online on: 13 May 2020

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Review Open Access

Circular RNAs in gastric cancer: Biomarkers for early diagnosis (Review)

Chun‑Mei Yang, Guang‑Lei Qiao, Li‑Na Song, Shisan Bao, Li‑Jun Ma
Pages: 465-473
Published online on: 14 May 2020

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Article Open Access

TGF‑β1 induces N‑cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells

Taifu Hirano, Daishi Saito, Hiroyuki Yamada, Akira Ishisaki, Masaharu Kamo
Pages: 474-482
Published online on: 04 May 2020

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Article Open Access

Identification of key genes associated with the progression of intrahepatic cholangiocarcinoma using weighted gene co‑expression network analysis

Zi Ye, Zhirui Zeng, Da Wang, Shan Lei, Yiyi Shen, Zubing Chen
Pages: 483-494
Published online on: 13 May 2020

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Article Open Access

Downregulation of lncRNA PMS2L2 in patients with gastric adenocarcinoma predicts poor prognosis

Junping Bian, Guangchun Li, Zhen Zhang, Bin Liu
Pages: 495-500
Published online on: 28 April 2020

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Article Open Access

Correlation between preoperatively predicted and postoperatively observed renal function using an imaging‑based approach: A retrospective cohort study

Jingchao Liu, Chuanxin Tian, Zhaocun Zhang, Guanwen Zhou, Benkang Shi, Haifeng Zhao, Xianzhou Jiang
Pages: 501-508
Published online on: 04 May 2020

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Article Open Access

High KIAA1522 expression predicts a poor prognosis in patients with hepatocellular carcinoma

Yongzheng Xu, Chuandong Sun, Bing Han, Yue Xi, Mao Zhang, Jing Yang, Zongkai Chen
Pages: 509-516
Published online on: 06 May 2020

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Article Open Access

Analysis of immune‑related signatures of colorectal cancer identifying two different immune phenotypes: Evidence for immune checkpoint inhibitor therapy

Gang Chen, Lin Wang, Tongwei Diao, Ying Chen, Chengbo Cao, Xindong Zhang
Pages: 517-524
Published online on: 13 May 2020

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Article Open Access

The age of paraffin block influences biomarker levels in archival breast cancer samples

Hong Chen, Qing‑Qing Fang, Bo Wang
Pages: 525-532
Published online on: 04 May 2020

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Article Open Access

Selective inhibition of HDAC6 sensitizes cutaneous T‑cell lymphoma to PI3K inhibitors

Malgorzata Bobrowicz, Aleksander Slusarczyk, Joanna Domagala, Michal Dwojak, Desislava Ignatova, Yun‑Tsan Chang, Christoph Iselin, Nina Miazek‑Zapala, Katsiaryna Marhelava, Emmanuella Guenova, Magdalena Winiarska
Pages: 533-540
Published online on: 06 May 2020

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Article Open Access

Clinicopathological and mutational differences between tumors with multiple metastases and single lung metastasis in colorectal cancer

Yuka Yanai, Takuo Hayashi, Yoichi Akazawa, Noboru Yatagai, Sho Tsuyama, Takashi Yao, Tsuyoshi Saito
Pages: 541-550
Published online on: 14 May 2020

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Article Open Access

SPAG6 silencing induces autophagic cell death in SKM‑1 cells via the AMPK/mTOR/ULK1 signaling pathway

Meng Zhang, Jie Luo, Xiaohua Luo, Lin Liu
Pages: 551-560
Published online on: 13 May 2020

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Article Open Access

Germline mutations in MEN1 are associated with the tumorigenesis of pituitary adenoma associated with meningioma

Haibo Zhu, Yazhou Miao, Yutao Shen, Jing Guo, Weiyan Xie, Sida Zhao, Wei Dong, Yazhuo Zhang, Chuzhong Li
Pages: 561-568
Published online on: 13 May 2020

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Article Open Access

In vitro and in vivo evaluation of the safety and efficacy of a novel liquid fiducial marker for image‑guided radiotherapy

Liang‑Chao Sun, Yi Su, Xing‑Chen Ding, Dong‑Shui Xu, Cheng‑Ming Li, Lu  Wang, Wan‑Long Li, Xin‑Dong Sun, Jin‑Ming Yu, Xue Meng
Pages: 569-580
Published online on: 06 May 2020

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Article Open Access

PSMD9 expression correlates with recurrence after radiotherapy in patients with cervical cancer

Frank Köster, Lisa Sauer, Friederike Hoellen, Julika Ribbat‑Idel, Karen Bräutigam, Achim Rody, Constanze Banz‑Jansen
Pages: 581-588
Published online on: 14 May 2020

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Article Open Access

Exosomes derived from endoplasmic reticulum‑stressed liver cancer cells enhance the expression of cytokines in macrophages via the STAT3 signaling pathway

Chengqun He, Wei Hua, Jiatao Liu, Lulu Fan, Hua Wang, Guoping Sun
Pages: 589-600
Published online on: 13 May 2020

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lncRNA KCNQ1OT1 knockdown inhibits colorectal cancer cell proliferation, migration and invasiveness via thePI3K/AKT pathway

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Elevated levels of IL‑17A and IL‑35 in plasma and bronchoalveolar lavage fluid are associated with checkpoint inhibitor pneumonitis in patients with non‑small cell lung cancer

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Tubeimoside I induces autophagy in HepG2 cells by activating the AMP‑activated protein kinase signaling pathway

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Downregulation of CLCA4 expression is associated with the development and progression of colorectal cancer

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PRR11 and SKA2 promote the proliferation, migration and invasion of esophageal carcinoma cells

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P2Y2R has a significant correlation with Notch‑4 in patients with breast cancer

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Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway

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Genomic DNA methylation profiling indicates immune response following thermal ablation treatment for HBV‑associated hepatocellular carcinoma

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Long non‑coding RNA NPBWR1‑2 affects the development of ovarian cancer via multiple microRNAs

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Diagnostic value of NSE factor combined with ultrasound hemodynamic indexes in cervical lymph node metastasis of lung cancer

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Prognostic significance of high triglyceride and apolipoprotein B levels in patients with stage III and high-risk stage II colorectal cancer undergoing curative surgery

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Long non‑coding RNA AC023794.4‑201 exerts a tumor‑suppressive function in laryngeal squamous cell cancer and may serve as a potential prognostic biomarker

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SATB2 knockdown decreases hypoxia‑induced autophagy and stemness in oral squamous cell carcinoma

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Propofol induces ROS‑mediated intrinsic apoptosis and migration in triple‑negative breast cancer cells

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Salvia bowleyana Dunn root is a novel source of salvianolic acid B and displays antitumor effects against gastric cancer cells

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Downregulation of ST3GAL5 is associated with muscle invasion, high grade and a poor prognosis in patients with bladder cancer

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Expression of HIF‑1α is a predictive marker of the efficacy of neoadjuvant chemotherapy for locally advanced cervical cancer

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Antitumor immunity targeting fibroblast activation protein‑α in a mouse Lewis lung carcinoma model

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A novel antitumor dithiocarbamate compound inhibits the EGFR/AKT signaling pathway and induces apoptosis in esophageal cancer cells

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Associations between the expression of SCCA, MTA1, P16, Ki‑67 and the infection of high‑risk HPV in cervical lesions

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Long non‑coding RNA SNHG7 inhibits NLRP3‑dependent pyroptosis by targeting the miR‑34a/SIRT1 axis in liver cancer

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Effect of erlotinib combined with cisplatin on IL‑6 and IL‑12 in mice with Lewis lung cancer

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Expression of lncRNA‑HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact

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Effects of miR-135a-5p and miR-141 on proliferation, invasion and apoptosis of colorectal cancer SW620 cells

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Comparison of long‑term treatment outcomes of T2N0M0 laryngeal squamous cell carcinoma using different treatment methods

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Comparison of Risk of Ovarian Malignancy Algorithm and cancer antigen 125 to discriminate between benign ovarian tumor and early‑stage ovarian cancer according to imaging tumor subtypes

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Identification and validation of seven prognostic long non‑coding RNAs in oral squamous cell carcinoma

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Article

Abnormal polarization of macrophage‑like cells in the peripheral blood of patients with glioma

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Promoter methylation of tumor suppressor genes induced by human papillomavirus in cervical cancer

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2‑Deoxy‑D‑glucose enhances the anti‑cancer effects of idarubicin on idarubicin‑resistant P388 leukemia cells

Taisuke Matsuo, Yumiko Konya, Eri Hirayama, Yasuyuki Sadzuka
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Article

Promoter hypermethylation of cysteine dioxygenase type 1 in patients with non‑small cell lung cancer

Wei Yin, Xiang Wang, Yunping Li, Bin Wang, Mingzhe Song, Alicia Hulbert, Chen Chen, Fenglei Yu
Pages: 967-973
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Article

Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance

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Pages: 974-980
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[Retracted] Relationship between DLK1 gene promoter region DNA methylation and non-small cell lung cancer biological behavior

Zhaokui Zhong, Yongting Ye, Wei Guo, Yi He, Weicai Hu
Pages: 981-981
Published online on: 27 April 2020

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January-2026 Volume 31 Issue 1

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CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

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Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

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Article Number: 36
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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
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Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

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Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
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Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
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Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
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Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Article Open Access

Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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