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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 20 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Novel prognostic molecular markers in lung cancer (Review)

Michał Puderecki, Justyna Szumiło, Barbara Marzec‑Kotarska
Pages: 9-18
Published online on: 15 April 2020

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Review Open Access

Endocrine disruptors from the environment affecting breast cancer (Review)

Gloria M. Calaf, Richard Ponce‑Cusi, Francisco Aguayo, Juan P. Muñoz, Tammy C. Bleak
Pages: 19-32
Published online on: 22 April 2020

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Article Open Access

Visceral obesity and cell cycle pathways serve as links in the association between bisphenol A exposure and breast cancer

Tsu‑Nai Wang, Pei‑Jing Yang, Yu‑Ting Tseng, Yi‑Shan Tsai, Po‑Lin Kuo, Chien‑Chih Chiu, Shih‑Shin Liang, Tsung‑Hua Hsieh, Ming‑Feng Hou, Eing‑Mei Tsai
Pages: 33-42
Published online on: 21 April 2020

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Article Open Access

YRDC is upregulated in non‑small cell lung cancer and promotes cell proliferation by decreasing cell apoptosis

Haibo Shen, Enkuo Zheng, Zhenhua Yang, Minglei Yang, Xiang Xu, Yinjie Zhou, Junjun Ni, Rui Li, Guofang Zhao
Pages: 43-52
Published online on: 21 April 2020

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Article Open Access

Chloroquine increases the anti‑cancer activity of epirubicin in A549 lung cancer cells

Ai‑Ling Liang, Jing Zhang, Shen‑Lin Du, Bin Zhang, Xuan Ma, Cui‑Yun Wu, Yong‑Jun Liu
Pages: 53-60
Published online on: 22 April 2020

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Article Open Access

AMPK decreases ERK1/2 activity and cancer cell sensitivity to nutrition deprivation by mediating a positive feedback loop involving eEF2K

Shujuan Tong, Tao Zhou, Yufen Meng, Dongqin Xu, Jianping Chen
Pages: 61-66
Published online on: 21 April 2020

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Article Open Access

Ubiquitin‑specific peptidase 17 promotes cisplatin resistance via PI3K/AKT activation in non‑small cell lung cancer

Shengchao Zhang, Zhenglang Xu, Jun Yuan, Hao Chen
Pages: 67-74
Published online on: 23 April 2020

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Article Open Access

Integrative transcriptome analysis identified a BMP signaling pathway‑regulated lncRNA AC068643.1 in IDH mutant and wild‑type glioblastomas

Guo‑Hao Huang, Yu‑Chun Pei, Lin Yang, Ke‑Jie Mou, Jun‑Hai Tang, Yan Xiang, Jun Liu, Sheng‑Qing Lv
Pages: 75-84
Published online on: 15 April 2020

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Article Open Access

Prognostic prediction of a 12‑methylation gene‑based risk score system on pancreatic adenocarcinoma

Daoqin Dou, Shaohua Yang, Jiren Zhang
Pages: 85-98
Published online on: 27 April 2020

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Article Open Access

Metastasis‑associated gene MAPK15 promotes the migration and invasion of osteosarcoma cells via the c‑Jun/MMPs pathway

Zexin Su, Bingsheng Yang, Zhirui Zeng, Shuang Zhu, Chenyang Wang, Shan Lei, Yongfa Jiang, Lijun Lin
Pages: 99-112
Published online on: 15 April 2020

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Article Open Access

Bioinformatics analysis of prognosis-related long non-coding RNAs in invasive breast carcinoma

Yuanyuan Hu, Xidong Gu, Yin Duan, Yong Shen, Xiaohong Xie
Pages: 113-122
Published online on: 21 April 2020

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Article Open Access

Application of the chemokine‑chemokine receptor axis increases the tumor‑targeted migration ability of cytokine‑induced killer cells in patients with colorectal cancer

Yunlian Zou, Jianhua Liang, Danyang Li, Jingjing Fang, Linping Wang, Jinli Wang, Jinping Zhang, Qiang Guo, Xinmin Yan, Hui Tang
Pages: 123-134
Published online on: 15 April 2020

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Article Open Access

Pathological roles of c‑Met in bladder cancer: Association with cyclooxygenase‑2, heme oxygenase‑1, vascular endothelial growth factor‑A and programmed death ligand 1

Yuta Mukae, Yasuyoshi Miyata, Yuichiro Nakamura, Kyohei Araki, Asato Otsubo, Tsutomu Yuno, Kensuke Mitsunari, Tomohiro Matsuo, Kojiro Ohba, Hideki Sakai
Pages: 135-144
Published online on: 15 April 2020

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Article Open Access

Distinct characteristics of dasatinib‑induced pyroptosis in gasdermin E‑expressing human lung cancer A549 cells and neuroblastoma SH‑SY5Y cells

Juan Zhang, Yang Chen, Qiyang He
Pages: 145-154
Published online on: 21 April 2020

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Article Open Access

Hypermethylation of tumor necrosis factor decoy receptor gene in non‑small cell lung cancer

Yuanlin Qi, Lin Qi, Minglian Qiu, Caiyun Yao, Mingfang Zhang, Jianbo Lin, Zhonghua Zheng, Chujia Chen, Hongxiang Li, Shiwei Duan
Pages: 155-164
Published online on: 22 April 2020

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Article Open Access

Downregulation of GNA14 in hepatocellular carcinoma indicates an unfavorable prognosis

Tao Yu, Siyu Lu, Wenjing Xie
Pages: 165-172
Published online on: 15 April 2020

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Article Open Access

MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA‑194

Hongming Wang, Fei Wang, Wenyu Ouyang, Xuejun Jiang, Wei Li
Pages: 173-182
Published online on: 21 April 2020

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Article Open Access

Efficacy and safety of CT‑guided 125I brachytherapy in elderly patients with non‑small cell lung cancer

Jing Zhao, Zheng Zhi, Hongtao Zhang, Jinxin Zhao, Yan Di, Ke Xu, Chunling Ma, Zezhou Liu, Aixia Sui, Juan Wang
Pages: 183-192
Published online on: 21 April 2020

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Article Open Access

Leveraging methylation to identify the potential causal genes associated with survival in lung adenocarcinoma and lung squamous cell carcinoma

Lu Liu, Ping Zeng, Sheng Yang, Zhongshang Yuan
Pages: 193-200
Published online on: 22 April 2020

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Article Open Access

PKUTHLP score: A comprehensive system to predict surgical approach in radical nephrectomy and thrombectomy

Xun Zhao, Zhuo Liu, Hongxian Zhang, Liwei Li, Shiying Tang, Guoliang Wang, Shudong Zhang, Shumin Wang, Xiaojun Tian, Lulin Ma
Pages: 201-208
Published online on: 23 April 2020

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Case Report Open Access

Epidural angiolipoma with concomitant intradural extramedullary capillary hemangioma at the same spinal level: A case report

Yongquan Cheng, Kaiwu Lu, Hui Jiang
Pages: 209-214
Published online on: 21 April 2020

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Article Open Access

Identification of genes associated with gastric cancer survival and construction of a nomogram to improve risk stratification for patients with gastric cancer

Yongfeng Ding, Yanyan Chen, Mengjie Wu, Linrong Li, Yingying Huang, Haiyong Wang, Haohao Wang, Xiongfei Yu, Nong Xu, Lisong Teng
Pages: 215-225
Published online on: 15 April 2020

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Article Open Access

Expression and regulation effects of chemokine receptor 7 in colon cancer cells

Xiang Li, Xuemei Wang, Zitao Li, Yanjun Liu, Liang Sang, Zhen Zhang, Yixia Zhang
Pages: 226-234
Published online on: 21 April 2020

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Article Open Access

lncRNA‑CD160 decreases the immunity of CD8+ T cells through epigenetic mechanisms in hepatitis B virus infection Retraction in /10.3892/ol.2025.15075

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Pages: 235-247
Published online on: 15 April 2020

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Article Open Access

STAT1 is a modulator of the expression of frequently rearranged in advanced T‑cell lymphomas 1 expression in U251 cells

Geng Guo, Shule Wang, Yining Hao, Yeqing Ren, Yongqiang Wu, Jianping Zhang, Dong Liu
Pages: 248-256
Published online on: 21 April 2020

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Article Open Access

P4HB modulates epithelial‑mesenchymal transition and the β‑catenin/Snail pathway influencing chemoresistance in liver cancer cells

Xing Ma, Jiening Wang, Juhua Zhuang, Xiaokun Ma, Ni Zheng, Yanan Song, Wei Xia
Pages: 257-265
Published online on: 23 April 2020

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Article Open Access

Hsa_circ_0038646 promotes cell proliferation and migration in colorectal cancer via miR‑331‑3p/GRIK3

Haipeng Du, Zhiguo He, Fumei Feng, Daming Chen, Lei Zhang, Jingzhen Bai, Huiguo Wu, Enkun Han, Jiansheng Zhang
Pages: 266-274
Published online on: 21 April 2020

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Article Open Access

Distinct diagnostic and prognostic values of γ‑aminobutyric acid type A receptor family genes in patients with colon adenocarcinoma

Ling Yan, Yi‑Zhen Gong, Meng‑Nan Shao, Guo‑Tian Ruan, Hai‑Lun Xie, Xi‑Wen Liao, Xiang‑Kun Wang, Quan‑Fa Han, Xin Zhou, Li‑Cheng Zhu, Feng Gao, Jia‑Liang Gan
Pages: 275-291
Published online on: 24 April 2020

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Article Open Access

Vitamin D3 mediates miR‑15a‑5p inhibition of liver cancer cell proliferation via targeting E2F3

Yulong Li, Qiang Lin, Su'e Chang, Rong Zhang, Jingjie Wang
Pages: 292-298
Published online on: 24 April 2020

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Article Open Access

miR‑208b‑5p inhibits invasion of non‑small cell lung cancer through the STAT3 pathway by targeting interleukin‑9

Jun Ma, Hong‑Feng Tong, Jie‑Huan Lin, Fu‑Nan Chen, Can‑Xing Wu, Cheng‑Zhang Cao, Jian Wu, Shu‑Qiao Hu
Pages: 299-307
Published online on: 23 April 2020

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Article Open Access

Prognostic and predictive value of immune/stromal-related gene biomarkers in renal cell carcinoma

Sen Wang, Xiangguang Zheng, Xinglu Chen, Xiaojun Shi, Sansan Chen
Pages: 308-316
Published online on: 24 April 2020

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Article Open Access

Significant diagnostic value of circulating tumour cells in colorectal cancer

Haijiao Yu, Ling Ma, Yubing Zhu, Wenxia Li, Lei Ding, Hong Gao
Pages: 317-325
Published online on: 15 April 2020

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Article Open Access

Neuregulin 1 enhances cell adhesion molecule L1 like expression levels and promotes malignancy in human glioma

Wen‑Wen Lin, Guan‑Yong Ou, Jia‑Zhe Lin, San‑Jun Yi, Wei‑Cheng Yao, Hong‑Chao Pan, Wei‑Jiang Zhao
Pages: 326-336
Published online on: 21 April 2020

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Article Open Access

Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β‑catenin signaling pathway in colon cancer

Jiayu Mao, Xueqi Chen, Chunsaier Wang, Wenbin Li, Jingnan Li
Pages: 337-345
Published online on: 16 April 2020

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Article Open Access

Combination treatment of gemcitabine and sorafenib exerts a synergistic inhibitory effect on non‑small cell lung cancer in vitro and in vivo via the epithelial‑to‑mesenchymal transition process

Shanshan Jiang, Rong Wang, Xuan Zhang, Feihua Wu, Shengnan Li, Yongfang Yuan
Pages: 346-356
Published online on: 15 April 2020

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Article Open Access

Inhibitory effect of dihydromyricetin on the proliferation of JAR cells and its mechanism of action

Yanzhen Zuo, Yanjie Lu, Qian Xu, Dayong Sun, Xiujun Liang, Xiaoru Li, Yuhong Li
Pages: 357-363
Published online on: 16 April 2020

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Article Open Access

Serum concentration of sex hormone‑binding globulin in healthy volunteers and patients with breast cancer stratified by sex and age

Se Jung Park, Tae Soo Kim, Kyu Hyun Park, Woo Sun Kwon, Jin Ju Kim
Pages: 364-372
Published online on: 21 April 2020

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Article Open Access

Claudin 10 acts as a novel biomarker for the prognosis of patients with ovarian cancer

Zhongjun Li, Wenting Xuan, Lishan Huang, Niankun Chen, Zhiyong Hou, Biyan Lu, Chuangyu Wen, Suran Huang
Pages: 373-381
Published online on: 21 April 2020

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Article Open Access

Comprehensive characterization of driver genes in diffuse large B cell lymphoma

Zheng Fan, Renzhi Pei, Keya Sha, Lieguang Chen, Tiantian Wang, Ying Lu
Pages: 382-390
Published online on: 21 April 2020

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Article

The effect of TKI therapy and chemotherapy treatment delivery sequence on total progression‑free survival in patients with advanced EGFR‑mutated NSCLC

Jie Han, Yan Xu, Yumei Zhou, Aiju Yang, Jianfeng Cui, Pengxiang Chen, Hongyu Zhao, Xingqin Zhou, Chaoyan Shen, Jinming Yu, Heng Lu
Pages: 391-400
Published online on: 15 April 2020

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Article

Ensemble classification for predicting the malignancy level of pulmonary nodules on chest computed tomography images

Ning Xiao, Yan Qiang, Muhammad Bilal Zia, Sanhu Wang, Jianhong Lian
Pages: 401-408
Published online on: 27 April 2020

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Article Open Access

Role of lymph node dissection in radical cystectomy

Keyi Wang, Heng Shi, Weipu Mao, Lei Yin, Guangchun Wang, Donglai Fan, Jinbo Xie, Weiyi Li, Bo Peng
Pages: 409-419
Published online on: 21 April 2020

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Article

Chemoresistance‑associated alternative splicing signatures in serous ovarian cancer

Tianshui Sun, Qing Yang
Pages: 420-430
Published online on: 21 April 2020

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Review Open Access

Oncology during the COVID‑19 pandemic: challenges, dilemmas and the psychosocial impact on cancer patients (Review)

Konstantinos Tsamakis, Maria Gavriatopoulou, Dimitrios Schizas, Athina Stravodimou, Aikaterini Mougkou, Dimitrios Tsiptsios, Vasileios Sioulas, Eleftherios Spartalis, Athanasios D. Sioulas, Charalampos Tsamakis, Nikolaos Charalampakis, Christoph Mueller, Donna Arya, Paul Zarogoulidis, Demetrios A. Spandidos, Meletios A. Dimopoulos, Charalabos Papageorgiou, Emmanouil Rizos
Pages: 441-447
Published online on: 08 May 2020

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Review Open Access

Pathogenesis of pediatric B‑cell acute lymphoblastic leukemia: Molecular pathways and disease treatments (Review)

Fang‑Liang Huang, En‑Chih Liao, Chia‑Ling Li, Chung‑Yang Yen, Sheng‑Jie Yu
Pages: 448-454
Published online on: 04 May 2020

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Review Open Access

Signal transducer and activator of transcription 6 as a target in colon cancer therapy (Review)

Yael Delgado‑Ramirez, Vaneesa Colly, Giovanni Villanueva Gonzalez, Sonia Leon‑Cabrera
Pages: 455-464
Published online on: 13 May 2020

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Review Open Access

Circular RNAs in gastric cancer: Biomarkers for early diagnosis (Review)

Chun‑Mei Yang, Guang‑Lei Qiao, Li‑Na Song, Shisan Bao, Li‑Jun Ma
Pages: 465-473
Published online on: 14 May 2020

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Article Open Access

TGF‑β1 induces N‑cadherin expression by upregulating Sox9 expression and promoting its nuclear translocation in human oral squamous cell carcinoma cells

Taifu Hirano, Daishi Saito, Hiroyuki Yamada, Akira Ishisaki, Masaharu Kamo
Pages: 474-482
Published online on: 04 May 2020

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Article Open Access

Identification of key genes associated with the progression of intrahepatic cholangiocarcinoma using weighted gene co‑expression network analysis

Zi Ye, Zhirui Zeng, Da Wang, Shan Lei, Yiyi Shen, Zubing Chen
Pages: 483-494
Published online on: 13 May 2020

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Article Open Access

Downregulation of lncRNA PMS2L2 in patients with gastric adenocarcinoma predicts poor prognosis

Junping Bian, Guangchun Li, Zhen Zhang, Bin Liu
Pages: 495-500
Published online on: 28 April 2020

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Article Open Access

Correlation between preoperatively predicted and postoperatively observed renal function using an imaging‑based approach: A retrospective cohort study

Jingchao Liu, Chuanxin Tian, Zhaocun Zhang, Guanwen Zhou, Benkang Shi, Haifeng Zhao, Xianzhou Jiang
Pages: 501-508
Published online on: 04 May 2020

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Article Open Access

High KIAA1522 expression predicts a poor prognosis in patients with hepatocellular carcinoma

Yongzheng Xu, Chuandong Sun, Bing Han, Yue Xi, Mao Zhang, Jing Yang, Zongkai Chen
Pages: 509-516
Published online on: 06 May 2020

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Article Open Access

Analysis of immune‑related signatures of colorectal cancer identifying two different immune phenotypes: Evidence for immune checkpoint inhibitor therapy

Gang Chen, Lin Wang, Tongwei Diao, Ying Chen, Chengbo Cao, Xindong Zhang
Pages: 517-524
Published online on: 13 May 2020

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Article Open Access

The age of paraffin block influences biomarker levels in archival breast cancer samples

Hong Chen, Qing‑Qing Fang, Bo Wang
Pages: 525-532
Published online on: 04 May 2020

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Article Open Access

Selective inhibition of HDAC6 sensitizes cutaneous T‑cell lymphoma to PI3K inhibitors

Malgorzata Bobrowicz, Aleksander Slusarczyk, Joanna Domagala, Michal Dwojak, Desislava Ignatova, Yun‑Tsan Chang, Christoph Iselin, Nina Miazek‑Zapala, Katsiaryna Marhelava, Emmanuella Guenova, Magdalena Winiarska
Pages: 533-540
Published online on: 06 May 2020

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Article Open Access

Clinicopathological and mutational differences between tumors with multiple metastases and single lung metastasis in colorectal cancer

Yuka Yanai, Takuo Hayashi, Yoichi Akazawa, Noboru Yatagai, Sho Tsuyama, Takashi Yao, Tsuyoshi Saito
Pages: 541-550
Published online on: 14 May 2020

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Article Open Access

SPAG6 silencing induces autophagic cell death in SKM‑1 cells via the AMPK/mTOR/ULK1 signaling pathway

Meng Zhang, Jie Luo, Xiaohua Luo, Lin Liu
Pages: 551-560
Published online on: 13 May 2020

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Article Open Access

Germline mutations in MEN1 are associated with the tumorigenesis of pituitary adenoma associated with meningioma

Haibo Zhu, Yazhou Miao, Yutao Shen, Jing Guo, Weiyan Xie, Sida Zhao, Wei Dong, Yazhuo Zhang, Chuzhong Li
Pages: 561-568
Published online on: 13 May 2020

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Article Open Access

In vitro and in vivo evaluation of the safety and efficacy of a novel liquid fiducial marker for image‑guided radiotherapy

Liang‑Chao Sun, Yi Su, Xing‑Chen Ding, Dong‑Shui Xu, Cheng‑Ming Li, Lu  Wang, Wan‑Long Li, Xin‑Dong Sun, Jin‑Ming Yu, Xue Meng
Pages: 569-580
Published online on: 06 May 2020

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Article Open Access

PSMD9 expression correlates with recurrence after radiotherapy in patients with cervical cancer

Frank Köster, Lisa Sauer, Friederike Hoellen, Julika Ribbat‑Idel, Karen Bräutigam, Achim Rody, Constanze Banz‑Jansen
Pages: 581-588
Published online on: 14 May 2020

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Article Open Access

Exosomes derived from endoplasmic reticulum‑stressed liver cancer cells enhance the expression of cytokines in macrophages via the STAT3 signaling pathway

Chengqun He, Wei Hua, Jiatao Liu, Lulu Fan, Hua Wang, Guoping Sun
Pages: 589-600
Published online on: 13 May 2020

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Article Open Access

lncRNA KCNQ1OT1 knockdown inhibits colorectal cancer cell proliferation, migration and invasiveness via thePI3K/AKT pathway

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Elevated levels of IL‑17A and IL‑35 in plasma and bronchoalveolar lavage fluid are associated with checkpoint inhibitor pneumonitis in patients with non‑small cell lung cancer

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Tubeimoside I induces autophagy in HepG2 cells by activating the AMP‑activated protein kinase signaling pathway

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Downregulation of CLCA4 expression is associated with the development and progression of colorectal cancer

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P2Y2R has a significant correlation with Notch‑4 in patients with breast cancer

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Prognostic significance of high triglyceride and apolipoprotein B levels in patients with stage III and high-risk stage II colorectal cancer undergoing curative surgery

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Propofol induces ROS‑mediated intrinsic apoptosis and migration in triple‑negative breast cancer cells

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Expression of HIF‑1α is a predictive marker of the efficacy of neoadjuvant chemotherapy for locally advanced cervical cancer

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Antitumor immunity targeting fibroblast activation protein‑α in a mouse Lewis lung carcinoma model

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Associations between the expression of SCCA, MTA1, P16, Ki‑67 and the infection of high‑risk HPV in cervical lesions

Cuina Han, Fangfei Zhao, Chongyang Wan, Yanfang He, Yan Chen
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Effect of erlotinib combined with cisplatin on IL‑6 and IL‑12 in mice with Lewis lung cancer

Xu Zhang, Jinliang Chen, Hongsong Jin, Wei Zhao, Zhibo Chang, Huijing Wu
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Expression of lncRNA‑HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact

Lan Wu, Yanqing Shi, Baoguo Liu, Mengting Zhao
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Effects of miR-135a-5p and miR-141 on proliferation, invasion and apoptosis of colorectal cancer SW620 cells

Jian Wang, Jing Yang, Heng Zhang, Yusheng Liao, Dan Xu, Songlin Ma
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Comparison of Risk of Ovarian Malignancy Algorithm and cancer antigen 125 to discriminate between benign ovarian tumor and early‑stage ovarian cancer according to imaging tumor subtypes

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Identification and validation of seven prognostic long non‑coding RNAs in oral squamous cell carcinoma

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Abnormal polarization of macrophage‑like cells in the peripheral blood of patients with glioma

Yawei Guo, Wenming Hong, Pengying Zhang, Dafei Han, Yilong Fang, Jiajie Tu, Wei Wei
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Promoter methylation of tumor suppressor genes induced by human papillomavirus in cervical cancer

Pattamawadee Yanatatsaneejit, Kanwalat Chalertpet, Juthamard Sukbhattee, Irin Nuchcharoen, Piyathida Phumcharoen, Apiwat Mutirangura
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2‑Deoxy‑D‑glucose enhances the anti‑cancer effects of idarubicin on idarubicin‑resistant P388 leukemia cells

Taisuke Matsuo, Yumiko Konya, Eri Hirayama, Yasuyuki Sadzuka
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Promoter hypermethylation of cysteine dioxygenase type 1 in patients with non‑small cell lung cancer

Wei Yin, Xiang Wang, Yunping Li, Bin Wang, Mingzhe Song, Alicia Hulbert, Chen Chen, Fenglei Yu
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Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance

Qiong Luo, Suyun Zhang, Donghuan Zhang, Fang Yuan, Xiangqi Chen, Sheng Yang
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[Retracted] Relationship between DLK1 gene promoter region DNA methylation and non-small cell lung cancer biological behavior

Zhaokui Zhong, Yongting Ye, Wei Guo, Yi He, Weicai Hu
Pages: 981-981
Published online on: 27 April 2020

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CiteScore Rank: Q2: #178/415 Oncology

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Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
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Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
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Published online on: 24 March 2026

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Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
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Published online on: 19 March 2026

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Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
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Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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