Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer

  • Authors:
    • Wenbao Liu
    • Nanguang Xiu
    • Jinwei Zhao
    • Lianhao Zhao
  • View Affiliations

  • Published online on: June 24, 2020     https://doi.org/10.3892/ol.2020.11765
  • Pages: 2493-2498
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The present study aimed to evaluate the therapeutic effect of transcatheter arterial chemoembolization (TACE) combined with radioactive I‑125 (iodine‑125) seed implantation on liver cancer. A total of 38 liver cancer patients in the combined treatment group were treated with lobaplatin‑TACE combined with radioactive I‑125 seed implantation, while 45 patients in the TACE group were treated only with lobaplatin‑TACE. Patients were followed up for survival time, and the liver function, change in α‑fetoprotein (AFP) and side effects were evaluated. The average survival time of patients was 6.1 months in the TACE group and 8.2 months in the combined treatment group, and the overall survival was significantly different between the two groups (P<0.05). The response rate of lesions in the combined treatment group was superior to that observed in the TACE group, and the change in AFP in the TACE group was smaller than that in the combined treatment group. Improvement in the effects on most liver function indices in the combined treatment group were better than those in the TACE group. In addition, there were no differences in the side effects experienced between the two groups. Results of this study indicate that the effect of TACE combined with radioactive I‑125 seed implantation is superior to that of TACE alone for the treatment of liver cancer, which can further benefit patients.

Related Articles

Journal Cover

September-2020
Volume 20 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Liu W, Xiu N, Zhao J and Zhao L: Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer. Oncol Lett 20: 2493-2498, 2020
APA
Liu, W., Xiu, N., Zhao, J., & Zhao, L. (2020). Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer. Oncology Letters, 20, 2493-2498. https://doi.org/10.3892/ol.2020.11765
MLA
Liu, W., Xiu, N., Zhao, J., Zhao, L."Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer". Oncology Letters 20.3 (2020): 2493-2498.
Chicago
Liu, W., Xiu, N., Zhao, J., Zhao, L."Enhanced therapeutic effect of transcatheter arterial chemoembolization combined with radioactive I‑125 seed implantation on liver cancer". Oncology Letters 20, no. 3 (2020): 2493-2498. https://doi.org/10.3892/ol.2020.11765