|
1
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Global Burden of Disease Cancer C, ;
Fitzmaurice C, Allen C, et al: Global, regional, and national
cancer incidence, mortality, years of life lost, years lived with
disability, and disability-adjusted life-years for 32 cancer
groups, 1990 to 2015: A systematic analysis for the global burden
of disease study. JAMA Oncol. 3:524–548. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Cuyàs E, Corominas-Faja B and Menendez JA:
The nutritional phenome of EMT-induced cancer stem-like cells.
Oncotarget. 5:3970–3982. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Kuhajda FP: Fatty-acid synthase and human
cancer: New perspectives on its role in tumor biology. Nutrition.
16:202–208. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Smith S: The animal fatty acid synthase:
One gene, one polypeptide, seven enzymes. FASEB J. 8:1248–1259.
1994. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Hopperton KE, Duncan RE, Bazinet RP and
Archer MC: Fatty acid synthase plays a role in cancer metabolism
beyond providing fatty acids for phospholipid synthesis or
sustaining elevations in glycolytic activity. Exp Cell Res.
320:302–310. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li P, Tian W and Ma X: Alpha-mangostin
inhibits intracellular fatty acid synthase and induces apoptosis in
breast cancer cells. Mol Cancer. 13:1382014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Agostini M, Almeida LY, Bastos DC, Ortega
RM, Moreira FS, Seguin F, Zecchin KG, Raposo HF, Oliveira HC,
Amoêdo ND, et al: The fatty acid synthase inhibitor orlistat
reduces the growth and metastasis of orthotopic tongue oral
squamous cell carcinomas. Mol Cancer Ther. 13:585–595. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
De Schrijver E, Brusselmans K, Heyns W,
Verhoeven G and Swinnen JV: RNA interference-mediated silencing of
the fatty acid synthase gene attenuates growth and induces
morphological changes and apoptosis of LNCaP prostate cancer cells.
Cancer Res. 63:3799–3804. 2003.PubMed/NCBI
|
|
10
|
Grube S, Dünisch P, Freitag D, Klausnitzer
M, Sakr Y, Walter J, Kalff R and Ewald C: Overexpression of fatty
acid synthase in human gliomas correlates with the WHO tumor grade
and inhibition with Orlistat reduces cell viability and triggers
apoptosis. J Neurooncol. 118:277–287. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Veigel D, Wagner R, Stübiger G, Wuczkowski
M, Filipits M, Horvat R, Benhamú B, López-Rodríguez ML, Leisser A,
Valent P, et al: Fatty acid synthase is a metabolic marker of cell
proliferation rather than malignancy in ovarian cancer and its
precursor cells. Int J Cancer. 136:2078–2090. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Menendez JA and Lupu R: Fatty acid
synthase and the lipogenic phenotype in cancer pathogenesis. Nat
Rev Cancer. 7:763–777. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Epstein JI, Carmichael M and Partin AW:
OA-519 (fatty acid synthase) as an independent predictor of
pathologic state in adenocarcinoma of the prostate. Urology.
45:81–86. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Khan A, Aljarbou AN, Aldebasi YH, Faisal
SM and Khan MA: Resveratrol suppresses the proliferation of breast
cancer cells by inhibiting fatty acid synthase signaling pathway.
Cancer Epidemiol. 38:765–772. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zaytseva YY, Rychahou PG, Gulhati P,
Elliott VA, Mustain WC, OConnor K, Morris AJ, Sunkara M, Weiss HL,
Lee EY, et al: Inhibition of fatty acid synthase attenuates
CD44-associated signaling and reduces metastasis in colorectal
cancer. Cancer Res. 72:1504–1517. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yoon S, Lee MY, Park SW, Moon JS, Koh YK,
Ahn YH, Park BW and Kim KS: Up-regulation of acetyl-CoA carboxylase
alpha and fatty acid synthase by human epidermal growth factor
receptor 2 at the translational level in breast cancer cells. J
Biol Chem. 282:26122–26131. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Camp RL, Dolled-Filhart M and Rimm DL:
X-tile: A new bio-informatics tool for biomarker assessment and
outcome-based cut-point optimization. Clin Cancer Res.
10:7252–7259. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Yu W, Chai H, Li Y, Zhao H, Xie X, Zheng
H, Wang C, Wang X, Yang G, Cai X, et al: Increased expression of
CYP4Z1 promotes tumor angiogenesis and growth in human breast
cancer. Toxicol Appl Pharmacol. 264:73–83. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Maina EG, Madivoli ES, Ouma JA, Ogilo JK
and Kenya JM: Evaluation of nutritional value of Asystasia
mysorensis and Sesamum angustifolia and their potential
contribution to human health. Food Sci Nutr. 7:2176–2185. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Sun L, Yao Y, Pan G, Zhan S, Shi W, Lu T,
Yuan J, Tian K, Jiang L, Song S, et al: Small interfering
RNA-mediated knockdown of fatty acid synthase attenuates the
proliferation and metastasis of human gastric cancer cells via the
mTOR/Gli1 signaling pathway. Oncol Lett. 16:594–602.
2018.PubMed/NCBI
|
|
21
|
Wang X, Tian J, Zhao Q, Yang N, Ying P,
Peng X, Zou D, Zhu Y, Zhong R, Gao Y, et al: Functional
characterization of a low-frequency V1937I variant in FASN
associated with susceptibility to esophageal squamous cell
carcinoma. Arch Toxicol. 94:2039–2046. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Mashima T, Seimiya H and Tsuruo T: De novo
fatty-acid synthesis and related pathways as molecular targets for
cancer therapy. Br J Cancer. 100:1369–1372. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chen T, Zhou L, Li H, Tian Y, Li J, Dong
L, Zhao Y and Wei D: Fatty acid synthase affects expression of ErbB
receptors in epithelial to mesenchymal transition of breast cancer
cells and invasive ductal carcinoma. Oncol Lett. 14:5934–5946.
2017.PubMed/NCBI
|
|
24
|
Shen J, Yan L, Liu S, Ambrosone CB and
Zhao H: Plasma metabolomic profiles in breast cancer patients and
healthy controls: By race and tumor receptor subtypes. Transl
Oncol. 6:757–765. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Lv W and Yang T: Identification of
possible biomarkers for breast cancer from free fatty acid profiles
determined by GC-MS and multivariate statistical analysis. Clin
Biochem. 45:127–133. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mohammadzadeh F, Mosayebi G, Montazeri V
and Darabi M, Fayezi S, Shaaker M, Rahmati M, Baradaran B,
Mehdizadeh A and Darabi M: Fatty acid composition of tissue
cultured breast carcinoma and the effect of stearoyl-CoA desaturase
1 inhibition. J Breast Cancer. 17:136–142. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Calligaris D, Caragacianu D, Liu X, Norton
I, Thompson CJ, Richardson AL, Golshan M, Easterling ML, Santagata
S, Dillon DA, et al: Application of desorption electrospray
ionization mass spectrometry imaging in breast cancer margin
analysis. Proc Natl Acad Sci USA. 111:15184–15189. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Conceição LL, Dias MM, Pessoa MC, Pena GD,
Mendes MC, Neves CV, Hermsdorff HH, Freitas RN and Peluzio MD:
Difference in fatty acids composition of breast adipose tissue in
women with breast cancer and benign breast disease. Nutr Hosp.
33:1354–1360. 2016. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Binker-Cosen MJ, Richards D, Oliver B,
Gaisano HY, Binker MG and Cosen-Binker LI: Palmitic acid increases
invasiveness of pancreatic cancer cells AsPC-1 through
TLR4/ROS/NF-κB/MMP-9 signaling pathway. Biochem Biophys Res Commun.
484:152–158. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Röhrig F and Schulze A: The multifaceted
roles of fatty acid synthesis in cancer. Nat Rev Cancer.
16:732–749. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Hilvo M, Denkert C, Lehtinen L, Müller B,
Brockmöller S, Seppänen-Laakso T, Budczies J, Bucher E, Yetukuri L,
Castillo S, et al: Novel theranostic opportunities offered by
characterization of altered membrane lipid metabolism in breast
cancer progression. Cancer Res. 71:3236–3245. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Rysman E, Brusselmans K, Scheys K,
Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D,
Daniëls VW, Machiels J, et al: De novo lipogenesis protects cancer
cells from free radicals and chemotherapeutics by promoting
membrane lipid saturation. Cancer Res. 70:8117–8126. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li J, Dong L, Wei D, Wang X, Zhang S and
Li H: Fatty acid synthase mediates the epithelial-mesenchymal
transition of breast cancer cells. Int J Biol Sci. 10:171–180.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Guo S, Wang Y, Zhou D and Li Z:
Significantly increased monounsaturated lipids relative to
polyunsaturated lipids in six types of cancer microenvironment are
observed by mass spectrometry imaging. Sci Rep. 4:59592014.
View Article : Google Scholar : PubMed/NCBI
|
