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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Overexpression of rhophilin 2 promotes pancreatic ductal adenocarcinoma

Wentao Bo, Xielin Feng, Xiaoli Tang
Article Number: 76
Published online on: 25 November 2020

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Article Open Access

Circular dumbbell miR‑34a‑3p and ‑5p suppresses pancreatic tumor cell‑induced angiogenesis and activates macrophages

Manu Gnanamony, Lusine Demirkhanyan, Liang Ge, Paresh Sojitra, Sneha Bapana, Joseph A. Norton, Christopher S. Gondi
Article Number: 75
Published online on: 25 November 2020

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Review Open Access

Prognosis of segmentectomy in the treatment of stage IA non‑small cell lung cancer (Review)

Wenliang Bai, Shanqing Li
Article Number: 74
Published online on: 25 November 2020

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Article Open Access

Correlation analysis of serum cystatin C, uric acid and lactate dehydrogenase levels before chemotherapy on the prognosis of small‑cell lung cancer

Haocheng Wang, Dongfeng Shan, Ya Dong, Xue Yang, Linwei Zhang, Zhuang Yu
Article Number: 73
Published online on: 25 November 2020

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Article Open Access

Villin is a biomarker for reverse polarity in colorectal micropapillary carcinoma

Li Zhao, Shao-Yan Liu, Yu-Meng Li, Zhong-Tang Xiong
Article Number: 72
Published online on: 25 November 2020

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Article Open Access

Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Yuko Iida, Mayumi Okamoto-Κatsuyama, Shuichiro Maruoka, Kenji Mizumura, Tetsuo Shimizu, Sotaro Shikano, Mari Hikichi, Mai Takahashi, Kota Tsuya, Shinichi Okamoto, Toshio Inoue, Yoko Nakanishi, Noriaki Takahashi, Shinobu Masuda, Shu Hashimoto, Yasuhiro Gon
Article Number: 71
Published online on: 25 November 2020

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Article Open Access

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 70
Published online on: 25 November 2020

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Article Open Access

High expression of HVEM is associated with improved prognosis in intrahepatic cholangiocarcinoma

Bingqi Ma, Huijuan Meng, Ye Tian, Yingying Wang, Tianqiang Song, Ti Zhang, Qiang Wu, Yunlong Cui, Huikai Li, Wei Zhang, Qiang Li
Article Number: 69
Published online on: 25 November 2020

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Article Open Access

Post‑radiation circulating tumor DNA as a prognostic factor in locally advanced esophageal squamous cell carcinoma

Ru Jia, Chuan-Hua Zhao, Pan-Song Li, Rong-Rui Liu, Yun Zhang, Hai-E Chen, Lian-Peng Chang, Yu-Hua Gong, Yan-Fang Guan, Xin Yi, Jian-Ming Xu
Article Number: 68
Published online on: 25 November 2020

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Article Open Access

Lentiviral vector with a radiation‑inducible promoter, carrying the ING4 gene, mediates radiosensitization controlled by radiotherapy in cervical cancer cells

Tao Ma, Rui Guo, Xi Wang, Wen-Tong Shen, Min Zhu, Ye-Ning Jin, Hao-Ping Xu
Article Number: 67
Published online on: 25 November 2020

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Article Open Access

Effects of matrine in combination with cisplatin on liver cancer

Gaoyu Hu, Cong Cao, Zhihua Deng, Jun Li, Xihan Zhou, Zansong Huang, Chao Cen
Article Number: 66
Published online on: 25 November 2020

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Article Open Access

β‑hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells

Rylee Maldonado, Chloe Adrienna Talana, Cassaundra Song, Alyssa Dixon, Kahealani Uehara, Michael Weichhaus
Article Number: 65
Published online on: 23 November 2020

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Article Open Access

Histone deacetylase 6 inhibition in urothelial cancer as a potential new strategy for cancer treatment

Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Yuko Shirono, Vladimir Bilim, Yoshihiko Tomita
Article Number: 64
Published online on: 20 November 2020

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Article Open Access

The expression of trefoil factor 3 is related to histologic subtypes and invasiveness in lung adenocarcinoma

Wenjuan Luo, Shinichiro Tahara, Keisuke Kawasaki, Ayaka Kobayashi, Satoshi Nojima, Eiichi Morii
Article Number: 63
Published online on: 19 November 2020

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Article Open Access

Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 62
Published online on: 19 November 2020

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Article Open Access

Crizotinib changes the metabolic pattern and inhibits ATP production in A549 non‑small cell lung cancer cells

Sa Ye, Hong-Bin Zhou, Ying Chen, Kai-Qiang Li, Shan-Shan Jiang, Ke Hao
Article Number: 61
Published online on: 19 November 2020

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Article Open Access

Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network

Zikun Song, Yinjiang Zhang, Zheren Chen, Bicheng Zhang
Article Number: 60
Published online on: 19 November 2020

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Article Open Access

Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 59
Published online on: 19 November 2020

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Article Open Access

Circular RNA hsa_circ_0005114‑miR‑142‑3p/miR‑590‑5p-adenomatous polyposis coli protein axis as a potential target for treatment of glioma

Bo Wei, Le Wang, Jingwei Zhao
Article Number: 58
Published online on: 19 November 2020

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Review Open Access

Innate immune cells and their interaction with T cells in hepatocellular carcinoma (Review)

Guo-Qing Hong, Dong Cai, Jian-Ping Gong, Xing Lai
Article Number: 57
Published online on: 19 November 2020

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Article Open Access

Soluble CD40 ligand inhibits the growth of non‑Hodgkin's lymphoma cells through the JNK signaling pathway

Zhongxin Feng, Jishi Wang
Article Number: 56
Published online on: 18 November 2020

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Article Open Access

Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis

Min-Shik Sohn, Miae Kang, Seong-Man Kang, Sangwoo Bae
Article Number: 55
Published online on: 18 November 2020

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Article Open Access

Circulating exosomal miR‑125a‑5p as a novel biomarker for cervical cancer

Aixia Lv, Zengrong Tu, Yunhua Huang, Weiying Lu, Baoguo Xie
Article Number: 54
Published online on: 18 November 2020

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Article Open Access

LINC00565 promotes the progression of colorectal cancer by upregulating EZH2

Xiaxia Shao, Tao Zhao, Lei Xi, Yuhong Zhang, Jia He, Jie Zeng, Lichun Deng
Article Number: 53
Published online on: 18 November 2020

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Article Open Access

Nidogen 1 regulates proliferation and migration/invasion in murine claudin‑low mammary tumor cells

Rebecca Jagroop, Courtney J. Martin, Roger A. Moorehead
Article Number: 52
Published online on: 18 November 2020

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Article Open Access

Clinical characteristics and outcomes of 17 cases of inflammatory myofibroblastic tumor at a University Hospital in China

Wei Song, Yan Zhu
Article Number: 51
Published online on: 18 November 2020

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Article Open Access

Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia

Xiao-Cong Lin, Qin Yang, Wei-Yu Fu, Liu-Bo Lan, Hang Ding, Yu-Ming Zhang, Ning Li, Hai-Tao Zhang
Article Number: 50
Published online on: 18 November 2020

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Article

Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells

Yang Yang, Menglin Zhao, Ting Hu, Fang Su, Feng Qian, Zishu Wang
Article Number: 49
Published online on: 18 November 2020

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Article Open Access

Role of tesmin expression in non‑small cell lung cancer

Jedrzej Grzegrzolka, Mateusz Olbromski, Agnieszka Gomulkiewicz, Aleksandra Piotrowska, Natalia Glatzel‑Plucinska, Katarzyna Ratajczak, Patrycja Sputa‑Grzegrzolka, Adam Rzechonek, Bozena Werynska, Marzena Podhorska‑Okolow, Piotr Dziegiel
Article Number: 48
Published online on: 17 November 2020

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Article Open Access

Fibrinogen‑like protein 2 promotes the accumulation of myeloid‑derived suppressor cells in the hepatocellular carcinoma tumor microenvironment

Bo-Qian Liu, Zhi-Ye Bao, Jia-Yi Zhu, Hao Liu
Article Number: 47
Published online on: 17 November 2020

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Article Open Access

Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis

Xinlu Ren, Yi Dong, Miao Duan, Hui Zhang, Peng Gao
Article Number: 46
Published online on: 17 November 2020

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Article Open Access

Long non‑coding maternally expressed gene 3 regulates cigarette smoke extract‑induced apoptosis, inflammation and cytotoxicity by sponging miR‑181a‑2‑3p in 16HBE cells

Shiming Fan, Yan Ren, Wenli Zhang, Huawei Zhang, Cheng Wang
Article Number: 45
Published online on: 17 November 2020

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Article Open Access

Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non‑carcinogenic L929 fibroblast cells

Xiangru Li, Xiaoju Zhou, Ying Liu, Jingjing Fan, Hongjing  Huo, Jingjing Yao, Lin Wang, Ningning Ma
Article Number: 44
Published online on: 17 November 2020

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Review Open Access

Management of aggressive fibromatosis (Review)

Zhijun Zhang, Jian Shi, Tao Yang, Tongjun Liu, Kai Zhang
Article Number: 43
Published online on: 17 November 2020

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Article Open Access

Identification of the potential roles of ring finger protein 8 in TP53‑mutant breast cancer

Feng Zhao, Peibin Wang, Yan Guo, Qi Lu, Xu Kong, Dongwei Su, Hengyu Li, Guoping Liu, Chaoqian Liu
Article Number: 42
Published online on: 17 November 2020

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Article Open Access

High frequency of microsatellite instability and its substantial co‑existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer

Ha Thi Nguyen, Do Thanh Le, Quan Hong Duong, Vinay Bharadwaj Tatipamula, Bang Van Nguyen
Article Number: 41
Published online on: 13 November 2020

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Article Open Access

Overexpression of CTEN is associated with gefitinib resistance in non‑small cell lung cancer

Xiangdong Lu, Yao Zhang, Yukai Pan, Minmin Cao, Xie Zhou, Tingrong Zhang
Article Number: 40
Published online on: 13 November 2020

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Article Open Access

Knockdown of UCA1 restrains cell proliferation and metastasis of diffuse large B‑cell lymphoma by counteracting miR‑331‑3p expression

Minqing Zhang, Yiping Du, Jingmei Shang, Dongqing Zhang, Xiaoqing Dong, Hong Chen
Article Number: 39
Published online on: 13 November 2020

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Article Open Access

SDF1α/CXCR4 axis may be associated with the malignant progression of gastric cancer in the hypoxic tumor microenvironment

Masakazu Yashiro, Haruhito Kinoshita, Gen Tsujio, Tatsunari Fukuoka, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Shuhei Kushiyama, Shingo Togano, Kenji Kuroda, Takahiro Toyokawa, Masaichi Ohira
Article Number: 38
Published online on: 12 November 2020

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Article Open Access

Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c‑Myc and p53 substrates in patients with dysplastic nevi or melanoma

Julija Mozuraitiene, Zivile Gudleviciene, Ieva Vincerzevskiene, Aida Laurinaviciene, Justinas Pamedys
Article Number: 37
Published online on: 12 November 2020

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Article Open Access

CD204‑positive macrophages accumulate in breast cancer tumors with high levels of infiltrating lymphocytes and programmed death ligand‑1 expression

Mayuko Nagano, Kanako Saito, Yuji Kozuka, Masako Ichishi, Hiroto Yuasa, Aya Noro, Nao Imai, Mai Shibusawa, Mao Kimoto, Makoto Ishitobi, Yasutaka Tono, Hiroyasu Oda, Mikiya Ishihara, Toshiro Mizuno, Tomoko Ogawa, Naoyuki Katayama
Article Number: 36
Published online on: 12 November 2020

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Review Open Access

MicroRNA‑126: A new and promising player in lung cancer (Review)

Qijun Chen, Shuanghua Chen, Juanjuan Zhao, Ya Zhou, Lin Xu
Article Number: 35
Published online on: 12 November 2020

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Article Open Access

Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum

Xiao Wu, Liping Jiang, Zeng Zhang, Yanming He, Yilong Teng, Jiaqi Li, Shilin Yuan, Yanna Pan, Haohui Liang, Hongjie Yang, Ping Zhou
Article Number: 34
Published online on: 12 November 2020

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Article Open Access

miR‑4636 inhibits tumor cell proliferation, migration and invasion, and serves as a candidate clinical biomarker for gastric cancer

Jiaying Tang, Ying Hu, Chunjie Zhang, Cuixue Gong
Article Number: 33
Published online on: 12 November 2020

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Article Open Access

Autophagy and apoptosis induction by sesamin in MOLT‑4 and NB4 leukemia cells

Kamolchanok Deesrisak, Chawalit Chatupheeraphat, Sittiruk Roytrakul, Usanarat Anurathapan, Dalina Tanyong
Article Number: 32
Published online on: 12 November 2020

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Article Open Access

Metformin inhibits epithelial‑mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF‑1α/PKM2/STAT3 pathway

Weihuang Yin, Yang Liu, Xinchen Liu, Xiaozhou Ma, Bin Sun, Ziying Yu
Article Number: 31
Published online on: 11 November 2020

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Article Open Access

Cathepsin B is highly expressed in pancreatic cancer stem‑like cells and is associated with patients' surgical outcomes

Takuya Fujimoto, Ryouichi Tsunedomi, Satoshi Matsukuma, Kiyoshi Yoshimura, Atsunori Oga, Nobuyuki Fujiwara, Yasuhiro Fujiwara, Hiroto Matsui, Yoshitaro Shindo, Yukio Tokumitsu, Nobuaki Suzuki, Shogo Kobayashi, Shoichi Hazama, Hidetoshi Eguchi, Hiroaki Nagano
Article Number: 30
Published online on: 11 November 2020

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Article Open Access

Prognostic significance of an autophagy‑related long non‑coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma

Qingkun Jiang, Danfeng Xue, Fanzhe Shi, Jiaxuan Qiu
Article Number: 29
Published online on: 11 November 2020

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Article Open Access

Inhibitor for protein disulfide‑isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

Yohei Kaneya, Hideyuki Takata, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryota Kondo, Nobuhiko Taniai, Ryuji Ohashi, Hiroshi Yoshida, Zenya Naito
Article Number: 28
Published online on: 11 November 2020

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Article Open Access

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism

Shuo Xu, Tingting Chen, Lihua Dong, Tao Li, Hui Xue, Bo Gao, Xiaodong Ding, Hui Wang, Hua Li
Article Number: 27
Published online on: 11 November 2020

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Article Open Access

Downregulation of histone‑lysine N‑methyltransferase EZH2 inhibits cell viability and enhances chemosensitivity in lung cancer cells

Ziyang Cao, Wei Wu, Haiting Wei, Wei Zhang, Yan Huang, Zhengwei Dong
Article Number: 26
Published online on: 11 November 2020

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Article Open Access

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer

Cheng Song, Bo Pan, Xiao Yang, Wei Tang
Article Number: 25
Published online on: 11 November 2020

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Article Open Access

Potentiating activities of chrysin in the therapeutic efficacy of 5‑fluorouracil in gastric cancer cells

Sunyi Lee, Suk Kyeong Lee, Joohee Jung
Article Number: 24
Published online on: 11 November 2020

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Review Open Access

Regulation of microRNA‑497 expression in human cancer (Review)

Guanshui Luo, Ke He, Zhenglin Xia, Shuai Liu, Hong Liu, Guoan Xiang
Article Number: 23
Published online on: 11 November 2020

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Article Open Access

Thrombospondin‑1 is a prognostic biomarker and is correlated with tumor immune microenvironment in glioblastoma

Chunxiao Qi, Lei Lei, Jinqu Hu, Gang Wang, Jiyuan Liu, Shaowu Ou
Article Number: 22
Published online on: 09 November 2020

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Article Open Access

Individualized chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus classic chemotherapy in the treatment of breast cancer: A comparative effectiveness study

Juncheng Li, Peng Sun, Tao Huang, Shengdong He, Lingfan Li, Gang Xue
Article Number: 21
Published online on: 09 November 2020

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Article Open Access

ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3

Shuetsu Abe, Masahiro Iwasaki, Shutaro Habata, Tasuku Mariya, Masato Tamate, Motoki Matsuura, Seiro Satohisa, Tsuyoshi Saito
Article Number: 20
Published online on: 09 November 2020

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Article Open Access

Epithelial‑mesenchymal transition and metastatic ability of CD133+ colorectal cancer stem‑like cells under hypoxia

Masamichi Okada, Kazushige Kawai, Hirofumi Sonoda, Hiroshi Shiratori, Junko Kishikawa, Hiroshi Nagata, Hiroaki Nozawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Yuuki Iida, Hiroaki Ishii, Yuichiro Yokoyama, Hiroyuki Anzai, Kiyoshi Hasegawa, Soichiro Ishihara
Article Number: 19
Published online on: 09 November 2020

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Article Open Access

Network pharmacological systems study of Huang‑Lian‑Tang in the treatment of glioblastoma multiforme

Wangrui Liu, Wenhao Xu, Chuanyu Li, Junfei Xu, Ke Huang, Renyue Hu, Haineng Huang, Xiaojuan Liu
Article Number: 18
Published online on: 06 November 2020

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Review Open Access

Multiple functions of TBCK protein in neurodevelopment disorders and tumors (Review)

Jin Wu, Guanting Lu
Article Number: 17
Published online on: 06 November 2020

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Article Open Access

TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 16
Published online on: 06 November 2020

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Article Open Access

KRAS and NRAS mutation detection in circulating DNA from patients with metastatic colorectal cancer using BEAMing assay: Concordance with standard biopsy and clinical evaluation

Elena Lastraioli, Lorenzo Antonuzzo, Beatrice Fantechi, Luisa Di Cerbo, Alessandro Di Costanzo, Daniele Lavacchi, Miriam Armenio, Annarosa Arcangeli, Francesca Castiglione, Luca Messerini, Francesco Di Costanzo
Article Number: 15
Published online on: 06 November 2020

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The mechanism of and the association between interleukin‑27 and chemotherapeutic drug sensitivity in lung cancer

Bingdong Jiang, Wenbo Shi, Peng Li, Yanli Wu, Yun Li, Chuanming Bao
Article Number: 14
Published online on: 06 November 2020

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Inhibition of proliferation and migration and induction of apoptosis in glioma cells by silencing TLR4 expression levels via RNA interference

Yingzi Liu, Yingchao Ju, Jianghui Liu, Yuetong Chen, Xiangran Huo, Liang Liu
Article Number: 13
Published online on: 06 November 2020

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Correction Open Access

[Corrigendum] Impact of microRNA‑29b on natural killer cells in T‑cell acute lymphoblastic leukemia

Fengyan Jin, Zhonghua Du, Yang Tang, Lixia Wang, Yanping Yang
Article Number: 12
Published online on: 05 November 2020

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Article

Plasma plastin‑3: A tumor marker in patients with non‑small‑cell lung cancer treated with nivolumab

Kengo Kuriyama, Takehiko Yokobori, Makoto Sohda, Nobuhiro  Nakazawa, Toshiki  Yajima, Ichiro Naruse, Hiroyuki  Kuwano, Ken Shirabe, Kyoichi Kaira, Hiroshi Saeki
Article Number: 11
Published online on: 03 November 2020

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Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer

Kensuke Yamada, Shoichi Hazama, Nobuaki Suzuki, Ming Xu, Yuki Nakagami, Nobuyuki Fujiwara, Ryouichi Tsunedomi, Shin Yoshida, Shinobu Tomochika, Satoshi Matsukuma, Hiroto Matsui, Yukio Tokumitsu, Shinsuke Kanekiyo, Yoshitaro Shindo, Yusaku Watanabe, Michihisa Iida, Shigeru Takeda, Tatsuya Ioka, Tomio Ueno, Hiroyuki Ogihara, Yoshihiko Hamamoto, Yoshinobu Hoshii, Hiroo Kawano, Tomonobu Fujita, Yutaka Kawakami, Hiroaki Nagano
Article Number: 10
Published online on: 03 November 2020

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Review Open Access

Molecular characteristics of uveal melanoma and intraocular tumors (Review)

Periklis Katopodis, Mohammad S. Khalifa, Vladimir Anikin
Article Number: 9
Published online on: 03 November 2020

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Article Open Access

Aberrant methylation of GADD45A is associated with decreased radiosensitivity in cervical cancer through the PI3K/AKT signaling pathway

Meng Lou, Rong Li, Ting-Yuan Lang, Li-Ying Zhang, Qi Zhou, Li Li
Article Number: 8
Published online on: 03 November 2020

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Article

Long‑term model of colitis‑associated colorectal cancer suggests tumor spread mechanism and nature of cancer stem cells

Yuji Tanimura, Toshiro Fukui, Shunsuke Horitani, Yasushi Matsumoto, Sachi Miyamoto, Ryo Suzuki, Toshihiro Tanaka, Takashi Tomiyama, Tsukasa Ikeura, Yugo Ando, Akiyoshi Nishio, Kazuichi Okazaki
Article Number: 7
Published online on: 03 November 2020

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Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53

Rongfeng Liu, Hongchen Li, Yanzhao Xu, Xing Li, Xiaojin Guo, Jian Shi, Yanzhi Cui, Zhiyu Wang, Junfeng Liu
Article Number: 6
Published online on: 03 November 2020

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Article

Overexpression of microRNA‑124‑5p sensitizes non‑small cell lung cancer cells to treatment with 5‑fluorouracil via AEG‑1 regulation

Xiaoxia Tan, Chuancui Zhang, Weidong Gao, Bei Sun, Baozhen Jiang, Peng Song
Article Number: 5
Published online on: 03 November 2020

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Altered expression of microRNA‑92b‑3p predicts survival outcomes of patients with prostate cancer and functions as an oncogene in tumor progression

Gang Wang, Bo Cheng, Renfeng Jia, Bo Tan, Wenlong Liu
Article Number: 4
Published online on: 03 November 2020

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Review Open Access

Cell‑free DNA as a liquid biopsy for early detection of gastric cancer (Review)

Zheng-Bin Huang, Hai-Tao Zhang, Benjamin Yu, De-Hua Yu
Article Number: 3
Published online on: 03 November 2020

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Article Open Access

Clinical significance of interleukin‑10 concentration in the cerebrospinal fluid of patients with primary central nervous system lymphoma

Mingying Geng, Yang Song, He Xiao, Zhiyu Wu, Xiaojuan Deng, Chuan Chen, Ge Wang
Article Number: 2
Published online on: 03 November 2020

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Review Open Access

Roles of ten‑eleven translocation family proteins and their O‑linked β‑N‑acetylglucosaminylated forms in cancer development (Review)

Hong-Jiao Li, Yi Wang, Bing-Xin Li, Yang Yang, Feng  Guan, Xing-Chen Pang, Xiang Li
Article Number: 1
Published online on: 03 November 2020

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Yuji Nitta, Tomoko Uchiyama, Akihiko Yoshizawa, Ryo Miyata, Masatsugu Hamaji, Hirotaka Kajihara, Masayuki Takeda
Article Number: 148
Published online on: 25 February 2026

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Case Report Open Access

Gliosarcoma of the right cerebellar hemisphere and parahippocampal region: A case report and literature review

Fa Wu, Yulin Yang, Zaiqing Wang, Rui Jiang, Tingting Wu, Ting Yu, Peng Wang
Article Number: 147
Published online on: 25 February 2026

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Article Open Access

Preliminary evidence for the integration of CNAs, CN‑LOH and mutational profiles into the prognostic stratification of elderly patients with NPM1‑mutated acute myeloid leukemia

Li Gao, Chunxia Zhang, Ming Gong, Zhengyi Cao, Chundi Liu, Sijie Wang, Zhenling Li
Article Number: 146
Published online on: 25 February 2026

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Pro‑tumourigenic effects of DCAF13 on the progression of colorectal cancer

Wenqi Zhang, Rongrong Zhang, Mengxuan Jia, Shuting Lan, Fangyuan Liu, Qin Jin, Liya Su, Gang Liu
Article Number: 145
Published online on: 25 February 2026

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Review Open Access

Histone deacetylases: Function in tumor development and therapeutic prospects (Review)

Runling Lin, Yu Zhang, Hong Li, Fan Liang
Article Number: 144
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Role of EphA2‑PI3K signaling in vasculogenic mimicry induced by cancer‑associated fibroblasts in gastric cancer cells

Hee Sung Kim, You Jin Won, Ju Hee Shim, Hyun Ji Kim, Byung Sik Kim, Hea Nam Hong
Article Number: 143
Published online on: 24 February 2026

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Case Report

Gastric cancer in pregnancy: A case report

Jianhua Niu, Yan Gao, Yu Sun, Huixia Yang
Article Number: 142
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro

Giovanni Vanni Frajese, Monica Benvenuto, Massimo Fantini, Elena Ambrosin, Pamela Sacchetti, Laura Masuelli, Maria Gabriella Giganti, Andrea Modesti, Roberto Bei
Article Number: 141
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2

Fenmei Zhou, Juan Chen, Hairong Wang
Article Number: 140
Published online on: 16 February 2026

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Case Report Open Access

Penile metastasis from prostate cancer with CDK12 mutation: A case report and literature review

Qi Xiang, Yanwu Wang, Bin Yao, Huiwen Tang, Qiang Dang
Article Number: 139
Published online on: 16 February 2026

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Case Report

Successful treatment with tepotinib followed by pembrolizumab in pulmonary pleomorphic carcinoma harbouring a MET exon 14 skipping mutation: A case report

Susumu Tanaka, Yu Saida, Yumi Ando, Jun Arinami, Ryo Yamazaki, Tomoya Wakabayashi, Hiroki Watanabe, Kohei Kushiro, Ryo Suzuki, Naohiro Yanagimura, Masashi Arita, Miyuki Sato, Tomohiro Tanaka, Koichiro Nozaki, Satoshi Watanabe, Shuhei Kondo, Hajime Umezu, Toshiaki Kikuchi
Article Number: 138
Published online on: 12 February 2026

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Article Open Access

METTL5‑mediated m6A modification of 18S rRNA drives oral squamous cell carcinoma progression by enhancing CCND3 translation

Lianlian Liu, Surui Sheng, Xin Zheng, Shuojin Huang, Lu Wang, Dalong Shu, Leile Tang, Qianting He
Article Number: 137
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 136
Published online on: 12 February 2026

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Review Open Access

STOML2 promotes hepatocellular carcinoma cell proliferation, invasion and migration by activating the PI3K/AKT signaling pathway (Review)

Mengyan Li, Jianli Chen
Article Number: 135
Published online on: 11 February 2026

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Article

Fatty acid‑induced lipid accumulation promotes radiosensitization in Huh7 hepatocellular carcinoma cells

Haruto Tanaka, Yasushi Mariya, Satoru Monzen
Article Number: 134
Published online on: 11 February 2026

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Article Open Access

Lactylation‑based machine algorithm combined with multi‑omics analysis to predict prognosis in cervical cancer

Ruyue Wang, Li Ning, Xiu Li, Yating Xu, Yu Si, Hongting Zhao, Qingling Ren
Article Number: 133
Published online on: 11 February 2026

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Potential treatment benefits of a GLP‑1R antagonist in combination with immune checkpoint inhibitors in colorectal cancer

Zengqin Zhan, Chuncha Zhan, Lianqiao Li, Dan Lan, Guya Meng, Fan Chen
Article Number: 132
Published online on: 10 February 2026

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Article

Effect of the hsa‑microRNA 200c‑3p/ZEB1 loop in epithelial‑mesenchymal transition of ovarian cancer cells

Merve Senturk, Ece Gumusoglu‑Acar, Samet Topuz, Tuba Gunel
Article Number: 131
Published online on: 10 February 2026

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Article Open Access

Inhibition of IRE1α kinase increases ferroptosis resistance in triple‑negative breast cancer cells

Shuo Xu, Si-Qi Yang
Article Number: 130
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS

Yi Xiao, Taoran Deng, Changliang Su, Zhen Shang
Article Number: 129
Published online on: 09 February 2026

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Case Report Open Access

Metastatic breast cancer in primary lung cancer with compound EGFR mutations: A case report

Tianyao Yang, Yifan Xu, Xi Lin, Guodong Chen, Fangfang Wang
Article Number: 128
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen, Jia Li
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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