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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Overexpression of rhophilin 2 promotes pancreatic ductal adenocarcinoma

Wentao Bo, Xielin Feng, Xiaoli Tang
Article Number: 76
Published online on: 25 November 2020

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Article Open Access

Circular dumbbell miR‑34a‑3p and ‑5p suppresses pancreatic tumor cell‑induced angiogenesis and activates macrophages

Manu Gnanamony, Lusine Demirkhanyan, Liang Ge, Paresh Sojitra, Sneha Bapana, Joseph A. Norton, Christopher S. Gondi
Article Number: 75
Published online on: 25 November 2020

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Review Open Access

Prognosis of segmentectomy in the treatment of stage IA non‑small cell lung cancer (Review)

Wenliang Bai, Shanqing Li
Article Number: 74
Published online on: 25 November 2020

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Article Open Access

Correlation analysis of serum cystatin C, uric acid and lactate dehydrogenase levels before chemotherapy on the prognosis of small‑cell lung cancer

Haocheng Wang, Dongfeng Shan, Ya Dong, Xue Yang, Linwei Zhang, Zhuang Yu
Article Number: 73
Published online on: 25 November 2020

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Article Open Access

Villin is a biomarker for reverse polarity in colorectal micropapillary carcinoma

Li Zhao, Shao-Yan Liu, Yu-Meng Li, Zhong-Tang Xiong
Article Number: 72
Published online on: 25 November 2020

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Article Open Access

Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Yuko Iida, Mayumi Okamoto-Κatsuyama, Shuichiro Maruoka, Kenji Mizumura, Tetsuo Shimizu, Sotaro Shikano, Mari Hikichi, Mai Takahashi, Kota Tsuya, Shinichi Okamoto, Toshio Inoue, Yoko Nakanishi, Noriaki Takahashi, Shinobu Masuda, Shu Hashimoto, Yasuhiro Gon
Article Number: 71
Published online on: 25 November 2020

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Article Open Access

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways Corrigendum in /10.3892/ol.2026.15639

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 70
Published online on: 25 November 2020

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Article Open Access

High expression of HVEM is associated with improved prognosis in intrahepatic cholangiocarcinoma

Bingqi Ma, Huijuan Meng, Ye Tian, Yingying Wang, Tianqiang Song, Ti Zhang, Qiang Wu, Yunlong Cui, Huikai Li, Wei Zhang, Qiang Li
Article Number: 69
Published online on: 25 November 2020

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Article Open Access

Post‑radiation circulating tumor DNA as a prognostic factor in locally advanced esophageal squamous cell carcinoma

Ru Jia, Chuan-Hua Zhao, Pan-Song Li, Rong-Rui Liu, Yun Zhang, Hai-E Chen, Lian-Peng Chang, Yu-Hua Gong, Yan-Fang Guan, Xin Yi, Jian-Ming Xu
Article Number: 68
Published online on: 25 November 2020

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Article Open Access

Lentiviral vector with a radiation‑inducible promoter, carrying the ING4 gene, mediates radiosensitization controlled by radiotherapy in cervical cancer cells

Tao Ma, Rui Guo, Xi Wang, Wen-Tong Shen, Min Zhu, Ye-Ning Jin, Hao-Ping Xu
Article Number: 67
Published online on: 25 November 2020

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Article Open Access

Effects of matrine in combination with cisplatin on liver cancer

Gaoyu Hu, Cong Cao, Zhihua Deng, Jun Li, Xihan Zhou, Zansong Huang, Chao Cen
Article Number: 66
Published online on: 25 November 2020

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Article Open Access

β‑hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells

Rylee Maldonado, Chloe Adrienna Talana, Cassaundra Song, Alyssa Dixon, Kahealani Uehara, Michael Weichhaus
Article Number: 65
Published online on: 23 November 2020

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Article Open Access

Histone deacetylase 6 inhibition in urothelial cancer as a potential new strategy for cancer treatment

Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Yuko Shirono, Vladimir Bilim, Yoshihiko Tomita
Article Number: 64
Published online on: 20 November 2020

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Article Open Access

The expression of trefoil factor 3 is related to histologic subtypes and invasiveness in lung adenocarcinoma

Wenjuan Luo, Shinichiro Tahara, Keisuke Kawasaki, Ayaka Kobayashi, Satoshi Nojima, Eiichi Morii
Article Number: 63
Published online on: 19 November 2020

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Article Open Access

Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 62
Published online on: 19 November 2020

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Article Open Access

Crizotinib changes the metabolic pattern and inhibits ATP production in A549 non‑small cell lung cancer cells

Sa Ye, Hong-Bin Zhou, Ying Chen, Kai-Qiang Li, Shan-Shan Jiang, Ke Hao
Article Number: 61
Published online on: 19 November 2020

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Article Open Access

Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network

Zikun Song, Yinjiang Zhang, Zheren Chen, Bicheng Zhang
Article Number: 60
Published online on: 19 November 2020

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Article Open Access

Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration Corrigendum in /10.3892/ol.2026.15664

Peng Wang, Chun Wang, Chunying Liu
Article Number: 59
Published online on: 19 November 2020

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Article Open Access

Circular RNA hsa_circ_0005114‑miR‑142‑3p/miR‑590‑5p-adenomatous polyposis coli protein axis as a potential target for treatment of glioma

Bo Wei, Le Wang, Jingwei Zhao
Article Number: 58
Published online on: 19 November 2020

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Review Open Access

Innate immune cells and their interaction with T cells in hepatocellular carcinoma (Review)

Guo-Qing Hong, Dong Cai, Jian-Ping Gong, Xing Lai
Article Number: 57
Published online on: 19 November 2020

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Article Open Access

Soluble CD40 ligand inhibits the growth of non‑Hodgkin's lymphoma cells through the JNK signaling pathway

Zhongxin Feng, Jishi Wang
Article Number: 56
Published online on: 18 November 2020

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Article Open Access

Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis

Min-Shik Sohn, Miae Kang, Seong-Man Kang, Sangwoo Bae
Article Number: 55
Published online on: 18 November 2020

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Article Open Access

Circulating exosomal miR‑125a‑5p as a novel biomarker for cervical cancer

Aixia Lv, Zengrong Tu, Yunhua Huang, Weiying Lu, Baoguo Xie
Article Number: 54
Published online on: 18 November 2020

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Article Open Access

LINC00565 promotes the progression of colorectal cancer by upregulating EZH2

Xiaxia Shao, Tao Zhao, Lei Xi, Yuhong Zhang, Jia He, Jie Zeng, Lichun Deng
Article Number: 53
Published online on: 18 November 2020

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Article Open Access

Nidogen 1 regulates proliferation and migration/invasion in murine claudin‑low mammary tumor cells

Rebecca Jagroop, Courtney J. Martin, Roger A. Moorehead
Article Number: 52
Published online on: 18 November 2020

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Article Open Access

Clinical characteristics and outcomes of 17 cases of inflammatory myofibroblastic tumor at a University Hospital in China

Wei Song, Yan Zhu
Article Number: 51
Published online on: 18 November 2020

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Article Open Access

Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia

Xiao-Cong Lin, Qin Yang, Wei-Yu Fu, Liu-Bo Lan, Hang Ding, Yu-Ming Zhang, Ning Li, Hai-Tao Zhang
Article Number: 50
Published online on: 18 November 2020

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Article

Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells

Yang Yang, Menglin Zhao, Ting Hu, Fang Su, Feng Qian, Zishu Wang
Article Number: 49
Published online on: 18 November 2020

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Article Open Access

Role of tesmin expression in non‑small cell lung cancer

Jedrzej Grzegrzolka, Mateusz Olbromski, Agnieszka Gomulkiewicz, Aleksandra Piotrowska, Natalia Glatzel‑Plucinska, Katarzyna Ratajczak, Patrycja Sputa‑Grzegrzolka, Adam Rzechonek, Bozena Werynska, Marzena Podhorska‑Okolow, Piotr Dziegiel
Article Number: 48
Published online on: 17 November 2020

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Article Open Access

Fibrinogen‑like protein 2 promotes the accumulation of myeloid‑derived suppressor cells in the hepatocellular carcinoma tumor microenvironment

Bo-Qian Liu, Zhi-Ye Bao, Jia-Yi Zhu, Hao Liu
Article Number: 47
Published online on: 17 November 2020

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Article Open Access

Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis

Xinlu Ren, Yi Dong, Miao Duan, Hui Zhang, Peng Gao
Article Number: 46
Published online on: 17 November 2020

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Article Open Access

Long non‑coding maternally expressed gene 3 regulates cigarette smoke extract‑induced apoptosis, inflammation and cytotoxicity by sponging miR‑181a‑2‑3p in 16HBE cells

Shiming Fan, Yan Ren, Wenli Zhang, Huawei Zhang, Cheng Wang
Article Number: 45
Published online on: 17 November 2020

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Article Open Access

Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non‑carcinogenic L929 fibroblast cells

Xiangru Li, Xiaoju Zhou, Ying Liu, Jingjing Fan, Hongjing  Huo, Jingjing Yao, Lin Wang, Ningning Ma
Article Number: 44
Published online on: 17 November 2020

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Review Open Access

Management of aggressive fibromatosis (Review)

Zhijun Zhang, Jian Shi, Tao Yang, Tongjun Liu, Kai Zhang
Article Number: 43
Published online on: 17 November 2020

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Article Open Access

Identification of the potential roles of ring finger protein 8 in TP53‑mutant breast cancer

Feng Zhao, Peibin Wang, Yan Guo, Qi Lu, Xu Kong, Dongwei Su, Hengyu Li, Guoping Liu, Chaoqian Liu
Article Number: 42
Published online on: 17 November 2020

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Article Open Access

High frequency of microsatellite instability and its substantial co‑existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer

Ha Thi Nguyen, Do Thanh Le, Quan Hong Duong, Vinay Bharadwaj Tatipamula, Bang Van Nguyen
Article Number: 41
Published online on: 13 November 2020

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Article Open Access

Overexpression of CTEN is associated with gefitinib resistance in non‑small cell lung cancer

Xiangdong Lu, Yao Zhang, Yukai Pan, Minmin Cao, Xie Zhou, Tingrong Zhang
Article Number: 40
Published online on: 13 November 2020

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Article Open Access

Knockdown of UCA1 restrains cell proliferation and metastasis of diffuse large B‑cell lymphoma by counteracting miR‑331‑3p expression

Minqing Zhang, Yiping Du, Jingmei Shang, Dongqing Zhang, Xiaoqing Dong, Hong Chen
Article Number: 39
Published online on: 13 November 2020

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Article Open Access

SDF1α/CXCR4 axis may be associated with the malignant progression of gastric cancer in the hypoxic tumor microenvironment

Masakazu Yashiro, Haruhito Kinoshita, Gen Tsujio, Tatsunari Fukuoka, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Shuhei Kushiyama, Shingo Togano, Kenji Kuroda, Takahiro Toyokawa, Masaichi Ohira
Article Number: 38
Published online on: 12 November 2020

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Article Open Access

Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c‑Myc and p53 substrates in patients with dysplastic nevi or melanoma

Julija Mozuraitiene, Zivile Gudleviciene, Ieva Vincerzevskiene, Aida Laurinaviciene, Justinas Pamedys
Article Number: 37
Published online on: 12 November 2020

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Article Open Access

CD204‑positive macrophages accumulate in breast cancer tumors with high levels of infiltrating lymphocytes and programmed death ligand‑1 expression

Mayuko Nagano, Kanako Saito, Yuji Kozuka, Masako Ichishi, Hiroto Yuasa, Aya Noro, Nao Imai, Mai Shibusawa, Mao Kimoto, Makoto Ishitobi, Yasutaka Tono, Hiroyasu Oda, Mikiya Ishihara, Toshiro Mizuno, Tomoko Ogawa, Naoyuki Katayama
Article Number: 36
Published online on: 12 November 2020

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Review Open Access

MicroRNA‑126: A new and promising player in lung cancer (Review)

Qijun Chen, Shuanghua Chen, Juanjuan Zhao, Ya Zhou, Lin Xu
Article Number: 35
Published online on: 12 November 2020

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Article Open Access

Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum

Xiao Wu, Liping Jiang, Zeng Zhang, Yanming He, Yilong Teng, Jiaqi Li, Shilin Yuan, Yanna Pan, Haohui Liang, Hongjie Yang, Ping Zhou
Article Number: 34
Published online on: 12 November 2020

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Article Open Access

miR‑4636 inhibits tumor cell proliferation, migration and invasion, and serves as a candidate clinical biomarker for gastric cancer

Jiaying Tang, Ying Hu, Chunjie Zhang, Cuixue Gong
Article Number: 33
Published online on: 12 November 2020

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Article Open Access

Autophagy and apoptosis induction by sesamin in MOLT‑4 and NB4 leukemia cells

Kamolchanok Deesrisak, Chawalit Chatupheeraphat, Sittiruk Roytrakul, Usanarat Anurathapan, Dalina Tanyong
Article Number: 32
Published online on: 12 November 2020

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Article Open Access

Metformin inhibits epithelial‑mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF‑1α/PKM2/STAT3 pathway

Weihuang Yin, Yang Liu, Xinchen Liu, Xiaozhou Ma, Bin Sun, Ziying Yu
Article Number: 31
Published online on: 11 November 2020

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Article Open Access

Cathepsin B is highly expressed in pancreatic cancer stem‑like cells and is associated with patients' surgical outcomes

Takuya Fujimoto, Ryouichi Tsunedomi, Satoshi Matsukuma, Kiyoshi Yoshimura, Atsunori Oga, Nobuyuki Fujiwara, Yasuhiro Fujiwara, Hiroto Matsui, Yoshitaro Shindo, Yukio Tokumitsu, Nobuaki Suzuki, Shogo Kobayashi, Shoichi Hazama, Hidetoshi Eguchi, Hiroaki Nagano
Article Number: 30
Published online on: 11 November 2020

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Article Open Access

Prognostic significance of an autophagy‑related long non‑coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma

Qingkun Jiang, Danfeng Xue, Fanzhe Shi, Jiaxuan Qiu
Article Number: 29
Published online on: 11 November 2020

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Article Open Access

Inhibitor for protein disulfide‑isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

Yohei Kaneya, Hideyuki Takata, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryota Kondo, Nobuhiko Taniai, Ryuji Ohashi, Hiroshi Yoshida, Zenya Naito
Article Number: 28
Published online on: 11 November 2020

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Article Open Access

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism

Shuo Xu, Tingting Chen, Lihua Dong, Tao Li, Hui Xue, Bo Gao, Xiaodong Ding, Hui Wang, Hua Li
Article Number: 27
Published online on: 11 November 2020

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Article Open Access

Downregulation of histone‑lysine N‑methyltransferase EZH2 inhibits cell viability and enhances chemosensitivity in lung cancer cells

Ziyang Cao, Wei Wu, Haiting Wei, Wei Zhang, Yan Huang, Zhengwei Dong
Article Number: 26
Published online on: 11 November 2020

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Article Open Access

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer

Cheng Song, Bo Pan, Xiao Yang, Wei Tang
Article Number: 25
Published online on: 11 November 2020

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Article Open Access

Potentiating activities of chrysin in the therapeutic efficacy of 5‑fluorouracil in gastric cancer cells

Sunyi Lee, Suk Kyeong Lee, Joohee Jung
Article Number: 24
Published online on: 11 November 2020

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Review Open Access

Regulation of microRNA‑497 expression in human cancer (Review)

Guanshui Luo, Ke He, Zhenglin Xia, Shuai Liu, Hong Liu, Guoan Xiang
Article Number: 23
Published online on: 11 November 2020

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Article Open Access

Thrombospondin‑1 is a prognostic biomarker and is correlated with tumor immune microenvironment in glioblastoma

Chunxiao Qi, Lei Lei, Jinqu Hu, Gang Wang, Jiyuan Liu, Shaowu Ou
Article Number: 22
Published online on: 09 November 2020

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Article Open Access

Individualized chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus classic chemotherapy in the treatment of breast cancer: A comparative effectiveness study

Juncheng Li, Peng Sun, Tao Huang, Shengdong He, Lingfan Li, Gang Xue
Article Number: 21
Published online on: 09 November 2020

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Article Open Access

ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3

Shuetsu Abe, Masahiro Iwasaki, Shutaro Habata, Tasuku Mariya, Masato Tamate, Motoki Matsuura, Seiro Satohisa, Tsuyoshi Saito
Article Number: 20
Published online on: 09 November 2020

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Article Open Access

Epithelial‑mesenchymal transition and metastatic ability of CD133+ colorectal cancer stem‑like cells under hypoxia

Masamichi Okada, Kazushige Kawai, Hirofumi Sonoda, Hiroshi Shiratori, Junko Kishikawa, Hiroshi Nagata, Hiroaki Nozawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Yuuki Iida, Hiroaki Ishii, Yuichiro Yokoyama, Hiroyuki Anzai, Kiyoshi Hasegawa, Soichiro Ishihara
Article Number: 19
Published online on: 09 November 2020

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Article Open Access

Network pharmacological systems study of Huang‑Lian‑Tang in the treatment of glioblastoma multiforme

Wangrui Liu, Wenhao Xu, Chuanyu Li, Junfei Xu, Ke Huang, Renyue Hu, Haineng Huang, Xiaojuan Liu
Article Number: 18
Published online on: 06 November 2020

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Review Open Access

Multiple functions of TBCK protein in neurodevelopment disorders and tumors (Review)

Jin Wu, Guanting Lu
Article Number: 17
Published online on: 06 November 2020

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Article Open Access

TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells Corrigendum in /10.3892/ol.2026.15651

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 16
Published online on: 06 November 2020

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KRAS and NRAS mutation detection in circulating DNA from patients with metastatic colorectal cancer using BEAMing assay: Concordance with standard biopsy and clinical evaluation

Elena Lastraioli, Lorenzo Antonuzzo, Beatrice Fantechi, Luisa Di Cerbo, Alessandro Di Costanzo, Daniele Lavacchi, Miriam Armenio, Annarosa Arcangeli, Francesca Castiglione, Luca Messerini, Francesco Di Costanzo
Article Number: 15
Published online on: 06 November 2020

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The mechanism of and the association between interleukin‑27 and chemotherapeutic drug sensitivity in lung cancer

Bingdong Jiang, Wenbo Shi, Peng Li, Yanli Wu, Yun Li, Chuanming Bao
Article Number: 14
Published online on: 06 November 2020

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Inhibition of proliferation and migration and induction of apoptosis in glioma cells by silencing TLR4 expression levels via RNA interference

Yingzi Liu, Yingchao Ju, Jianghui Liu, Yuetong Chen, Xiangran Huo, Liang Liu
Article Number: 13
Published online on: 06 November 2020

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[Corrigendum] Impact of microRNA‑29b on natural killer cells in T‑cell acute lymphoblastic leukemia

Fengyan Jin, Zhonghua Du, Yang Tang, Lixia Wang, Yanping Yang
Article Number: 12
Published online on: 05 November 2020

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Article

Plasma plastin‑3: A tumor marker in patients with non‑small‑cell lung cancer treated with nivolumab

Kengo Kuriyama, Takehiko Yokobori, Makoto Sohda, Nobuhiro  Nakazawa, Toshiki  Yajima, Ichiro Naruse, Hiroyuki  Kuwano, Ken Shirabe, Kyoichi Kaira, Hiroshi Saeki
Article Number: 11
Published online on: 03 November 2020

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Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer

Kensuke Yamada, Shoichi Hazama, Nobuaki Suzuki, Ming Xu, Yuki Nakagami, Nobuyuki Fujiwara, Ryouichi Tsunedomi, Shin Yoshida, Shinobu Tomochika, Satoshi Matsukuma, Hiroto Matsui, Yukio Tokumitsu, Shinsuke Kanekiyo, Yoshitaro Shindo, Yusaku Watanabe, Michihisa Iida, Shigeru Takeda, Tatsuya Ioka, Tomio Ueno, Hiroyuki Ogihara, Yoshihiko Hamamoto, Yoshinobu Hoshii, Hiroo Kawano, Tomonobu Fujita, Yutaka Kawakami, Hiroaki Nagano
Article Number: 10
Published online on: 03 November 2020

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Molecular characteristics of uveal melanoma and intraocular tumors (Review)

Periklis Katopodis, Mohammad S. Khalifa, Vladimir Anikin
Article Number: 9
Published online on: 03 November 2020

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Aberrant methylation of GADD45A is associated with decreased radiosensitivity in cervical cancer through the PI3K/AKT signaling pathway

Meng Lou, Rong Li, Ting-Yuan Lang, Li-Ying Zhang, Qi Zhou, Li Li
Article Number: 8
Published online on: 03 November 2020

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Long‑term model of colitis‑associated colorectal cancer suggests tumor spread mechanism and nature of cancer stem cells

Yuji Tanimura, Toshiro Fukui, Shunsuke Horitani, Yasushi Matsumoto, Sachi Miyamoto, Ryo Suzuki, Toshihiro Tanaka, Takashi Tomiyama, Tsukasa Ikeura, Yugo Ando, Akiyoshi Nishio, Kazuichi Okazaki
Article Number: 7
Published online on: 03 November 2020

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Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53

Rongfeng Liu, Hongchen Li, Yanzhao Xu, Xing Li, Xiaojin Guo, Jian Shi, Yanzhi Cui, Zhiyu Wang, Junfeng Liu
Article Number: 6
Published online on: 03 November 2020

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Overexpression of microRNA‑124‑5p sensitizes non‑small cell lung cancer cells to treatment with 5‑fluorouracil via AEG‑1 regulation

Xiaoxia Tan, Chuancui Zhang, Weidong Gao, Bei Sun, Baozhen Jiang, Peng Song
Article Number: 5
Published online on: 03 November 2020

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Altered expression of microRNA‑92b‑3p predicts survival outcomes of patients with prostate cancer and functions as an oncogene in tumor progression

Gang Wang, Bo Cheng, Renfeng Jia, Bo Tan, Wenlong Liu
Article Number: 4
Published online on: 03 November 2020

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Cell‑free DNA as a liquid biopsy for early detection of gastric cancer (Review)

Zheng-Bin Huang, Hai-Tao Zhang, Benjamin Yu, De-Hua Yu
Article Number: 3
Published online on: 03 November 2020

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Clinical significance of interleukin‑10 concentration in the cerebrospinal fluid of patients with primary central nervous system lymphoma

Mingying Geng, Yang Song, He Xiao, Zhiyu Wu, Xiaojuan Deng, Chuan Chen, Ge Wang
Article Number: 2
Published online on: 03 November 2020

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Roles of ten‑eleven translocation family proteins and their O‑linked β‑N‑acetylglucosaminylated forms in cancer development (Review)

Hong-Jiao Li, Yi Wang, Bing-Xin Li, Yang Yang, Feng  Guan, Xing-Chen Pang, Xiang Li
Article Number: 1
Published online on: 03 November 2020

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June-2026 Volume 31 Issue 6

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CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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SCImago Journal Rank (SJR): 0.663

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Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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