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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2021 Volume 21 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Overexpression of rhophilin 2 promotes pancreatic ductal adenocarcinoma

Wentao Bo, Xielin Feng, Xiaoli Tang
Article Number: 76
Published online on: 25 November 2020

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Article Open Access

Circular dumbbell miR‑34a‑3p and ‑5p suppresses pancreatic tumor cell‑induced angiogenesis and activates macrophages

Manu Gnanamony, Lusine Demirkhanyan, Liang Ge, Paresh Sojitra, Sneha Bapana, Joseph A. Norton, Christopher S. Gondi
Article Number: 75
Published online on: 25 November 2020

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Review Open Access

Prognosis of segmentectomy in the treatment of stage IA non‑small cell lung cancer (Review)

Wenliang Bai, Shanqing Li
Article Number: 74
Published online on: 25 November 2020

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Article Open Access

Correlation analysis of serum cystatin C, uric acid and lactate dehydrogenase levels before chemotherapy on the prognosis of small‑cell lung cancer

Haocheng Wang, Dongfeng Shan, Ya Dong, Xue Yang, Linwei Zhang, Zhuang Yu
Article Number: 73
Published online on: 25 November 2020

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Article Open Access

Villin is a biomarker for reverse polarity in colorectal micropapillary carcinoma

Li Zhao, Shao-Yan Liu, Yu-Meng Li, Zhong-Tang Xiong
Article Number: 72
Published online on: 25 November 2020

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Article Open Access

Effective ferroptotic small-cell lung cancer cell death from SLC7A11 inhibition by sulforaphane

Yuko Iida, Mayumi Okamoto-Κatsuyama, Shuichiro Maruoka, Kenji Mizumura, Tetsuo Shimizu, Sotaro Shikano, Mari Hikichi, Mai Takahashi, Kota Tsuya, Shinichi Okamoto, Toshio Inoue, Yoko Nakanishi, Noriaki Takahashi, Shinobu Masuda, Shu Hashimoto, Yasuhiro Gon
Article Number: 71
Published online on: 25 November 2020

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Article Open Access

Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 70
Published online on: 25 November 2020

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Article Open Access

High expression of HVEM is associated with improved prognosis in intrahepatic cholangiocarcinoma

Bingqi Ma, Huijuan Meng, Ye Tian, Yingying Wang, Tianqiang Song, Ti Zhang, Qiang Wu, Yunlong Cui, Huikai Li, Wei Zhang, Qiang Li
Article Number: 69
Published online on: 25 November 2020

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Article Open Access

Post‑radiation circulating tumor DNA as a prognostic factor in locally advanced esophageal squamous cell carcinoma

Ru Jia, Chuan-Hua Zhao, Pan-Song Li, Rong-Rui Liu, Yun Zhang, Hai-E Chen, Lian-Peng Chang, Yu-Hua Gong, Yan-Fang Guan, Xin Yi, Jian-Ming Xu
Article Number: 68
Published online on: 25 November 2020

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Article Open Access

Lentiviral vector with a radiation‑inducible promoter, carrying the ING4 gene, mediates radiosensitization controlled by radiotherapy in cervical cancer cells

Tao Ma, Rui Guo, Xi Wang, Wen-Tong Shen, Min Zhu, Ye-Ning Jin, Hao-Ping Xu
Article Number: 67
Published online on: 25 November 2020

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Article Open Access

Effects of matrine in combination with cisplatin on liver cancer

Gaoyu Hu, Cong Cao, Zhihua Deng, Jun Li, Xihan Zhou, Zansong Huang, Chao Cen
Article Number: 66
Published online on: 25 November 2020

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Article Open Access

β‑hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells

Rylee Maldonado, Chloe Adrienna Talana, Cassaundra Song, Alyssa Dixon, Kahealani Uehara, Michael Weichhaus
Article Number: 65
Published online on: 23 November 2020

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Article Open Access

Histone deacetylase 6 inhibition in urothelial cancer as a potential new strategy for cancer treatment

Hiroo Kuroki, Tsutomu Anraku, Akira Kazama, Yuko Shirono, Vladimir Bilim, Yoshihiko Tomita
Article Number: 64
Published online on: 20 November 2020

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Article Open Access

The expression of trefoil factor 3 is related to histologic subtypes and invasiveness in lung adenocarcinoma

Wenjuan Luo, Shinichiro Tahara, Keisuke Kawasaki, Ayaka Kobayashi, Satoshi Nojima, Eiichi Morii
Article Number: 63
Published online on: 19 November 2020

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Article Open Access

Antitumour activity of TH1579, a novel MTH1 inhibitor, against castration‑resistant prostate cancer

Mingqiu Hu, Jing Ning, Likai Mao, Yuanyuan Yu, Yu Wu
Article Number: 62
Published online on: 19 November 2020

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Article Open Access

Crizotinib changes the metabolic pattern and inhibits ATP production in A549 non‑small cell lung cancer cells

Sa Ye, Hong-Bin Zhou, Ying Chen, Kai-Qiang Li, Shan-Shan Jiang, Ke Hao
Article Number: 61
Published online on: 19 November 2020

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Article Open Access

Identification of key genes in lung adenocarcinoma based on a competing endogenous RNA network

Zikun Song, Yinjiang Zhang, Zheren Chen, Bicheng Zhang
Article Number: 60
Published online on: 19 November 2020

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Article Open Access

Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 59
Published online on: 19 November 2020

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Article Open Access

Circular RNA hsa_circ_0005114‑miR‑142‑3p/miR‑590‑5p-adenomatous polyposis coli protein axis as a potential target for treatment of glioma

Bo Wei, Le Wang, Jingwei Zhao
Article Number: 58
Published online on: 19 November 2020

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Review Open Access

Innate immune cells and their interaction with T cells in hepatocellular carcinoma (Review)

Guo-Qing Hong, Dong Cai, Jian-Ping Gong, Xing Lai
Article Number: 57
Published online on: 19 November 2020

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Article Open Access

Soluble CD40 ligand inhibits the growth of non‑Hodgkin's lymphoma cells through the JNK signaling pathway

Zhongxin Feng, Jishi Wang
Article Number: 56
Published online on: 18 November 2020

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Article Open Access

Downregulation of APRIN expression increases cancer cell proliferation via an interleukin-6/STAT3/cyclin D axis

Min-Shik Sohn, Miae Kang, Seong-Man Kang, Sangwoo Bae
Article Number: 55
Published online on: 18 November 2020

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Article Open Access

Circulating exosomal miR‑125a‑5p as a novel biomarker for cervical cancer

Aixia Lv, Zengrong Tu, Yunhua Huang, Weiying Lu, Baoguo Xie
Article Number: 54
Published online on: 18 November 2020

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Article Open Access

LINC00565 promotes the progression of colorectal cancer by upregulating EZH2

Xiaxia Shao, Tao Zhao, Lei Xi, Yuhong Zhang, Jia He, Jie Zeng, Lichun Deng
Article Number: 53
Published online on: 18 November 2020

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Article Open Access

Nidogen 1 regulates proliferation and migration/invasion in murine claudin‑low mammary tumor cells

Rebecca Jagroop, Courtney J. Martin, Roger A. Moorehead
Article Number: 52
Published online on: 18 November 2020

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Article Open Access

Clinical characteristics and outcomes of 17 cases of inflammatory myofibroblastic tumor at a University Hospital in China

Wei Song, Yan Zhu
Article Number: 51
Published online on: 18 November 2020

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Article Open Access

Integrated analysis of microRNA and transcription factors in the bone marrow of patients with acute monocytic leukemia

Xiao-Cong Lin, Qin Yang, Wei-Yu Fu, Liu-Bo Lan, Hang Ding, Yu-Ming Zhang, Ning Li, Hai-Tao Zhang
Article Number: 50
Published online on: 18 November 2020

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Article

Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells

Yang Yang, Menglin Zhao, Ting Hu, Fang Su, Feng Qian, Zishu Wang
Article Number: 49
Published online on: 18 November 2020

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Article Open Access

Role of tesmin expression in non‑small cell lung cancer

Jedrzej Grzegrzolka, Mateusz Olbromski, Agnieszka Gomulkiewicz, Aleksandra Piotrowska, Natalia Glatzel‑Plucinska, Katarzyna Ratajczak, Patrycja Sputa‑Grzegrzolka, Adam Rzechonek, Bozena Werynska, Marzena Podhorska‑Okolow, Piotr Dziegiel
Article Number: 48
Published online on: 17 November 2020

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Article Open Access

Fibrinogen‑like protein 2 promotes the accumulation of myeloid‑derived suppressor cells in the hepatocellular carcinoma tumor microenvironment

Bo-Qian Liu, Zhi-Ye Bao, Jia-Yi Zhu, Hao Liu
Article Number: 47
Published online on: 17 November 2020

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Article Open Access

Abnormal expression of HNRNPA3 in multistep hepatocarcinogenesis

Xinlu Ren, Yi Dong, Miao Duan, Hui Zhang, Peng Gao
Article Number: 46
Published online on: 17 November 2020

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Article Open Access

Long non‑coding maternally expressed gene 3 regulates cigarette smoke extract‑induced apoptosis, inflammation and cytotoxicity by sponging miR‑181a‑2‑3p in 16HBE cells

Shiming Fan, Yan Ren, Wenli Zhang, Huawei Zhang, Cheng Wang
Article Number: 45
Published online on: 17 November 2020

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Article Open Access

Overexpression of monocarboxylate transporter 4 promotes the migration and invasion of non‑carcinogenic L929 fibroblast cells

Xiangru Li, Xiaoju Zhou, Ying Liu, Jingjing Fan, Hongjing  Huo, Jingjing Yao, Lin Wang, Ningning Ma
Article Number: 44
Published online on: 17 November 2020

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Review Open Access

Management of aggressive fibromatosis (Review)

Zhijun Zhang, Jian Shi, Tao Yang, Tongjun Liu, Kai Zhang
Article Number: 43
Published online on: 17 November 2020

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Article Open Access

Identification of the potential roles of ring finger protein 8 in TP53‑mutant breast cancer

Feng Zhao, Peibin Wang, Yan Guo, Qi Lu, Xu Kong, Dongwei Su, Hengyu Li, Guoping Liu, Chaoqian Liu
Article Number: 42
Published online on: 17 November 2020

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Article Open Access

High frequency of microsatellite instability and its substantial co‑existence with KRAS and BRAF mutations in Vietnamese patients with colorectal cancer

Ha Thi Nguyen, Do Thanh Le, Quan Hong Duong, Vinay Bharadwaj Tatipamula, Bang Van Nguyen
Article Number: 41
Published online on: 13 November 2020

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Article Open Access

Overexpression of CTEN is associated with gefitinib resistance in non‑small cell lung cancer

Xiangdong Lu, Yao Zhang, Yukai Pan, Minmin Cao, Xie Zhou, Tingrong Zhang
Article Number: 40
Published online on: 13 November 2020

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Article Open Access

Knockdown of UCA1 restrains cell proliferation and metastasis of diffuse large B‑cell lymphoma by counteracting miR‑331‑3p expression

Minqing Zhang, Yiping Du, Jingmei Shang, Dongqing Zhang, Xiaoqing Dong, Hong Chen
Article Number: 39
Published online on: 13 November 2020

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Article Open Access

SDF1α/CXCR4 axis may be associated with the malignant progression of gastric cancer in the hypoxic tumor microenvironment

Masakazu Yashiro, Haruhito Kinoshita, Gen Tsujio, Tatsunari Fukuoka, Yurie Yamamoto, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Shuhei Kushiyama, Shingo Togano, Kenji Kuroda, Takahiro Toyokawa, Masaichi Ohira
Article Number: 38
Published online on: 12 November 2020

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Article Open Access

Expression levels of FBXW7 and MDM2 E3 ubiquitin ligases and their c‑Myc and p53 substrates in patients with dysplastic nevi or melanoma

Julija Mozuraitiene, Zivile Gudleviciene, Ieva Vincerzevskiene, Aida Laurinaviciene, Justinas Pamedys
Article Number: 37
Published online on: 12 November 2020

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Article Open Access

CD204‑positive macrophages accumulate in breast cancer tumors with high levels of infiltrating lymphocytes and programmed death ligand‑1 expression

Mayuko Nagano, Kanako Saito, Yuji Kozuka, Masako Ichishi, Hiroto Yuasa, Aya Noro, Nao Imai, Mai Shibusawa, Mao Kimoto, Makoto Ishitobi, Yasutaka Tono, Hiroyasu Oda, Mikiya Ishihara, Toshiro Mizuno, Tomoko Ogawa, Naoyuki Katayama
Article Number: 36
Published online on: 12 November 2020

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Review Open Access

MicroRNA‑126: A new and promising player in lung cancer (Review)

Qijun Chen, Shuanghua Chen, Juanjuan Zhao, Ya Zhou, Lin Xu
Article Number: 35
Published online on: 12 November 2020

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Article Open Access

Pancreatic cancer cell apoptosis is induced by a proteoglycan extracted from Ganoderma lucidum

Xiao Wu, Liping Jiang, Zeng Zhang, Yanming He, Yilong Teng, Jiaqi Li, Shilin Yuan, Yanna Pan, Haohui Liang, Hongjie Yang, Ping Zhou
Article Number: 34
Published online on: 12 November 2020

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Article Open Access

miR‑4636 inhibits tumor cell proliferation, migration and invasion, and serves as a candidate clinical biomarker for gastric cancer

Jiaying Tang, Ying Hu, Chunjie Zhang, Cuixue Gong
Article Number: 33
Published online on: 12 November 2020

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Article Open Access

Autophagy and apoptosis induction by sesamin in MOLT‑4 and NB4 leukemia cells

Kamolchanok Deesrisak, Chawalit Chatupheeraphat, Sittiruk Roytrakul, Usanarat Anurathapan, Dalina Tanyong
Article Number: 32
Published online on: 12 November 2020

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Article Open Access

Metformin inhibits epithelial‑mesenchymal transition of oral squamous cell carcinoma via the mTOR/HIF‑1α/PKM2/STAT3 pathway

Weihuang Yin, Yang Liu, Xinchen Liu, Xiaozhou Ma, Bin Sun, Ziying Yu
Article Number: 31
Published online on: 11 November 2020

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Article Open Access

Cathepsin B is highly expressed in pancreatic cancer stem‑like cells and is associated with patients' surgical outcomes

Takuya Fujimoto, Ryouichi Tsunedomi, Satoshi Matsukuma, Kiyoshi Yoshimura, Atsunori Oga, Nobuyuki Fujiwara, Yasuhiro Fujiwara, Hiroto Matsui, Yoshitaro Shindo, Yukio Tokumitsu, Nobuaki Suzuki, Shogo Kobayashi, Shoichi Hazama, Hidetoshi Eguchi, Hiroaki Nagano
Article Number: 30
Published online on: 11 November 2020

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Article Open Access

Prognostic significance of an autophagy‑related long non‑coding RNA signature in patients with oral and oropharyngeal squamous cell carcinoma

Qingkun Jiang, Danfeng Xue, Fanzhe Shi, Jiaxuan Qiu
Article Number: 29
Published online on: 11 November 2020

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Article Open Access

Inhibitor for protein disulfide‑isomerase family A member 3 enhances the antiproliferative effect of inhibitor for mechanistic target of rapamycin in liver cancer: An in vitro study on combination treatment with everolimus and 16F16

Yohei Kaneya, Hideyuki Takata, Ryuichi Wada, Shoko Kure, Kousuke Ishino, Mitsuhiro Kudo, Ryota Kondo, Nobuhiko Taniai, Ryuji Ohashi, Hiroshi Yoshida, Zenya Naito
Article Number: 28
Published online on: 11 November 2020

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Article Open Access

Fatty acid synthase promotes breast cancer metastasis by mediating changes in fatty acid metabolism

Shuo Xu, Tingting Chen, Lihua Dong, Tao Li, Hui Xue, Bo Gao, Xiaodong Ding, Hui Wang, Hua Li
Article Number: 27
Published online on: 11 November 2020

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Article Open Access

Downregulation of histone‑lysine N‑methyltransferase EZH2 inhibits cell viability and enhances chemosensitivity in lung cancer cells

Ziyang Cao, Wei Wu, Haiting Wei, Wei Zhang, Yan Huang, Zhengwei Dong
Article Number: 26
Published online on: 11 November 2020

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Article Open Access

Polyphyllin VII suppresses cell proliferation, the cell cycle and cell migration in colorectal cancer

Cheng Song, Bo Pan, Xiao Yang, Wei Tang
Article Number: 25
Published online on: 11 November 2020

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Article Open Access

Potentiating activities of chrysin in the therapeutic efficacy of 5‑fluorouracil in gastric cancer cells

Sunyi Lee, Suk Kyeong Lee, Joohee Jung
Article Number: 24
Published online on: 11 November 2020

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Review Open Access

Regulation of microRNA‑497 expression in human cancer (Review)

Guanshui Luo, Ke He, Zhenglin Xia, Shuai Liu, Hong Liu, Guoan Xiang
Article Number: 23
Published online on: 11 November 2020

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Article Open Access

Thrombospondin‑1 is a prognostic biomarker and is correlated with tumor immune microenvironment in glioblastoma

Chunxiao Qi, Lei Lei, Jinqu Hu, Gang Wang, Jiyuan Liu, Shaowu Ou
Article Number: 22
Published online on: 09 November 2020

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Article Open Access

Individualized chemotherapy guided by the expression of ERCC1, RRM1, TUBB3, TYMS and TOP2A genes versus classic chemotherapy in the treatment of breast cancer: A comparative effectiveness study

Juncheng Li, Peng Sun, Tao Huang, Shengdong He, Lingfan Li, Gang Xue
Article Number: 21
Published online on: 09 November 2020

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Article Open Access

ERα increases endometrial cancer cell resistance to cisplatin via upregulation of BAG3

Shuetsu Abe, Masahiro Iwasaki, Shutaro Habata, Tasuku Mariya, Masato Tamate, Motoki Matsuura, Seiro Satohisa, Tsuyoshi Saito
Article Number: 20
Published online on: 09 November 2020

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Article Open Access

Epithelial‑mesenchymal transition and metastatic ability of CD133+ colorectal cancer stem‑like cells under hypoxia

Masamichi Okada, Kazushige Kawai, Hirofumi Sonoda, Hiroshi Shiratori, Junko Kishikawa, Hiroshi Nagata, Hiroaki Nozawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Yuuki Iida, Hiroaki Ishii, Yuichiro Yokoyama, Hiroyuki Anzai, Kiyoshi Hasegawa, Soichiro Ishihara
Article Number: 19
Published online on: 09 November 2020

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Article Open Access

Network pharmacological systems study of Huang‑Lian‑Tang in the treatment of glioblastoma multiforme

Wangrui Liu, Wenhao Xu, Chuanyu Li, Junfei Xu, Ke Huang, Renyue Hu, Haineng Huang, Xiaojuan Liu
Article Number: 18
Published online on: 06 November 2020

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Review Open Access

Multiple functions of TBCK protein in neurodevelopment disorders and tumors (Review)

Jin Wu, Guanting Lu
Article Number: 17
Published online on: 06 November 2020

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Article Open Access

TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 16
Published online on: 06 November 2020

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KRAS and NRAS mutation detection in circulating DNA from patients with metastatic colorectal cancer using BEAMing assay: Concordance with standard biopsy and clinical evaluation

Elena Lastraioli, Lorenzo Antonuzzo, Beatrice Fantechi, Luisa Di Cerbo, Alessandro Di Costanzo, Daniele Lavacchi, Miriam Armenio, Annarosa Arcangeli, Francesca Castiglione, Luca Messerini, Francesco Di Costanzo
Article Number: 15
Published online on: 06 November 2020

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The mechanism of and the association between interleukin‑27 and chemotherapeutic drug sensitivity in lung cancer

Bingdong Jiang, Wenbo Shi, Peng Li, Yanli Wu, Yun Li, Chuanming Bao
Article Number: 14
Published online on: 06 November 2020

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Inhibition of proliferation and migration and induction of apoptosis in glioma cells by silencing TLR4 expression levels via RNA interference

Yingzi Liu, Yingchao Ju, Jianghui Liu, Yuetong Chen, Xiangran Huo, Liang Liu
Article Number: 13
Published online on: 06 November 2020

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Correction Open Access

[Corrigendum] Impact of microRNA‑29b on natural killer cells in T‑cell acute lymphoblastic leukemia

Fengyan Jin, Zhonghua Du, Yang Tang, Lixia Wang, Yanping Yang
Article Number: 12
Published online on: 05 November 2020

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Article

Plasma plastin‑3: A tumor marker in patients with non‑small‑cell lung cancer treated with nivolumab

Kengo Kuriyama, Takehiko Yokobori, Makoto Sohda, Nobuhiro  Nakazawa, Toshiki  Yajima, Ichiro Naruse, Hiroyuki  Kuwano, Ken Shirabe, Kyoichi Kaira, Hiroshi Saeki
Article Number: 11
Published online on: 03 November 2020

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Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer

Kensuke Yamada, Shoichi Hazama, Nobuaki Suzuki, Ming Xu, Yuki Nakagami, Nobuyuki Fujiwara, Ryouichi Tsunedomi, Shin Yoshida, Shinobu Tomochika, Satoshi Matsukuma, Hiroto Matsui, Yukio Tokumitsu, Shinsuke Kanekiyo, Yoshitaro Shindo, Yusaku Watanabe, Michihisa Iida, Shigeru Takeda, Tatsuya Ioka, Tomio Ueno, Hiroyuki Ogihara, Yoshihiko Hamamoto, Yoshinobu Hoshii, Hiroo Kawano, Tomonobu Fujita, Yutaka Kawakami, Hiroaki Nagano
Article Number: 10
Published online on: 03 November 2020

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Molecular characteristics of uveal melanoma and intraocular tumors (Review)

Periklis Katopodis, Mohammad S. Khalifa, Vladimir Anikin
Article Number: 9
Published online on: 03 November 2020

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Aberrant methylation of GADD45A is associated with decreased radiosensitivity in cervical cancer through the PI3K/AKT signaling pathway

Meng Lou, Rong Li, Ting-Yuan Lang, Li-Ying Zhang, Qi Zhou, Li Li
Article Number: 8
Published online on: 03 November 2020

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Article

Long‑term model of colitis‑associated colorectal cancer suggests tumor spread mechanism and nature of cancer stem cells

Yuji Tanimura, Toshiro Fukui, Shunsuke Horitani, Yasushi Matsumoto, Sachi Miyamoto, Ryo Suzuki, Toshihiro Tanaka, Takashi Tomiyama, Tsukasa Ikeura, Yugo Ando, Akiyoshi Nishio, Kazuichi Okazaki
Article Number: 7
Published online on: 03 November 2020

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Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53

Rongfeng Liu, Hongchen Li, Yanzhao Xu, Xing Li, Xiaojin Guo, Jian Shi, Yanzhi Cui, Zhiyu Wang, Junfeng Liu
Article Number: 6
Published online on: 03 November 2020

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Overexpression of microRNA‑124‑5p sensitizes non‑small cell lung cancer cells to treatment with 5‑fluorouracil via AEG‑1 regulation

Xiaoxia Tan, Chuancui Zhang, Weidong Gao, Bei Sun, Baozhen Jiang, Peng Song
Article Number: 5
Published online on: 03 November 2020

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Altered expression of microRNA‑92b‑3p predicts survival outcomes of patients with prostate cancer and functions as an oncogene in tumor progression

Gang Wang, Bo Cheng, Renfeng Jia, Bo Tan, Wenlong Liu
Article Number: 4
Published online on: 03 November 2020

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Review Open Access

Cell‑free DNA as a liquid biopsy for early detection of gastric cancer (Review)

Zheng-Bin Huang, Hai-Tao Zhang, Benjamin Yu, De-Hua Yu
Article Number: 3
Published online on: 03 November 2020

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Clinical significance of interleukin‑10 concentration in the cerebrospinal fluid of patients with primary central nervous system lymphoma

Mingying Geng, Yang Song, He Xiao, Zhiyu Wu, Xiaojuan Deng, Chuan Chen, Ge Wang
Article Number: 2
Published online on: 03 November 2020

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Roles of ten‑eleven translocation family proteins and their O‑linked β‑N‑acetylglucosaminylated forms in cancer development (Review)

Hong-Jiao Li, Yi Wang, Bing-Xin Li, Yang Yang, Feng  Guan, Xing-Chen Pang, Xiang Li
Article Number: 1
Published online on: 03 November 2020

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Pathological response to neoadjuvant chemotherapy and survival in patients with breast cancer: A multicentric retrospective study

Evrard Narcisse Séka, Danielle Asmao Traoré, Corneille Téa Saki, Kadjatou Traoré, Amara Gozana Tuo, Brahima Doukouré
Article Number: 93
Published online on: 02 January 2026

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Case Report

Curative surgery enabled by radiotherapy in rectal cancer: A case report

Sofia E. Sánchez‑De‑Toca Gómez, Fernando Mendoza Moreno, Patricia Urbón Sánchez, Felix Mañes Jiménez, Yousef Allaoua Massaoui, Lucas Casalduero García, Pablo Barat Betrán, Alejandra Julia Lopez Marsellá, María Mejías Ledesma, Alberto Vilar Tabanera, Manuel Diez Alonso, Alberto Gutiérrez Calvo
Article Number: 92
Published online on: 31 December 2025

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Metastatic urothelial carcinoma of the urethra and glans penis with reported implantation via the urine: A case report

Piotr Kalinowski, Paweł Nalej, Beata Grochulska‑Nalazek, Tomasz Kalinowski, Tomasz Demkow, Olga Kuczkiewicz‑Siemion, Roman Romaniuk
Article Number: 91
Published online on: 31 December 2025

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Serum expression levels of HOTAIR and miR‑646 in endometrial cancer

Rizki̇ Hari̇smunandar, Hande Karpuzoğlu, Yağmur Mi̇nareci̇, Hamdullah Sözen, Samet Topuz, Canan Küçükgergi̇n, A. Fati̇h Aydin
Article Number: 90
Published online on: 30 December 2025

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Article

Predictive value analysis of CEA, CA125 and CYFRA21‑1 levels in evaluating the efficacy of tislelizumab combined with gemcitabine‑cisplatin chemotherapy in patients with advanced non‑small cell lung cancer

Langyue Wang, Tianyu Gou, Yang Cui, Meng Li, Yu Wang
Article Number: 89
Published online on: 30 December 2025

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Case Report Open Access

Individualized management strategies for advanced non‑small cell lung cancer with EGFR exon 19 deletion and L861Q compound mutations based on circulating tumor DNA monitoring: A case report

Xiaobang Zhu, Ye Sun, Ruirui Cai, Wenbin Zhang, Xiangwei Zhang, Ailing Song, Xiaoyan Chen, Cuicui Liu, Jianping Zhou
Article Number: 88
Published online on: 23 December 2025

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Case Report

Metastasis of lung adenocarcinoma to follicular thyroid carcinoma combined with papillary thyroid carcinoma in the contralateral lobe: A case report

Cuicui Wang, Yihang Yang, Liquan Bi, Xiaohong Liu
Article Number: 87
Published online on: 23 December 2025

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Article

Proteins Lamin A and SUN1 are exclusively decreased in nuclear grade 4 clear cell renal cell carcinoma

Rio Shibanuma, Sayaka Kobayashi, Momoka Konno, Rio Kaneko, Yoshimi Nishijima, Hayato Ikota, Masashi Nomura, Kazuhiro Suzuki, Hideaki Yokoo, Masanao Saio
Article Number: 86
Published online on: 23 December 2025

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Extended cycles of anti‑GD2 antibody dinutuximab beta treatment combined with chemotherapy in patients with relapsed or refractory neuroblastoma: A retrospective study

Zhiqi Gong, Suyi Kang, Chuanfeng Bai, Yang Li, Xuedi Yu, Kun Shang, Yixiang Song, Fangfang Cheng, Jingfu Wang
Article Number: 85
Published online on: 23 December 2025

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Case Report Open Access

Primary intracranial extraskeletal myxoid chondrosarcoma in a teenager with unusual frontal location and surgical complications: A case report and literature review

Helu Wang, Fang Wang, Hongtao Zhang
Article Number: 84
Published online on: 19 December 2025

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Article Open Access

Estrogen receptor α expression in tumor‑infiltrating lymphocytes from patients with endometrial cancer

Marcin A. Jedryka, Anna Slawek, Paulina Kubik, Daria Lorek, Anna Ewa Kedzierska, Andrzej Czekanski, Rafał Matkowski, Anna Chelmonska-Soyta
Article Number: 83
Published online on: 19 December 2025

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Systemic treatment for a young patient with stage IV melanoma: A case report

Xiaoyu Huang, Lianhai Zhao, Pingan Wang, Dong Xue
Article Number: 82
Published online on: 19 December 2025

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High expression of G3BP1 is associated with poor prognosis in breast invasive carcinoma

Jingjing Li, Zhiqiang Zong, Jian Shen, Jiahao Wang, Xuan Zhou, Wei Shi, Jia Li, Hong Zhao, Yunwen Yan, Fanfan Li
Article Number: 81
Published online on: 18 December 2025

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Article

DHX15 overexpression suppresses colorectal cancer cell line proliferation

Yuki Ii, Kosuke Saita, Toshiro Iwagawa, Shingo Ito, Kiichi Sugimoto, Kazuhiro Sakamoto, Sumiko Watanabe
Article Number: 80
Published online on: 18 December 2025

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Article

Construction of a novel prediction model based on albumin‑hemoglobin score and serum microRNA-497‑5p for prognosis of patients with stage II‑III colorectal cancer

Qian Wang, Hailiang Wang, Lingling Liu, Zhen Wang
Article Number: 79
Published online on: 17 December 2025

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Dual role of IFNγ in reprogramming the undifferentiated pleomorphic sarcoma cell line JBT19 towards cytotoxic chemotherapy and antitumor immunity

Pavla Taborska, Dmitry Stakheev, Daniel Smrz
Article Number: 78
Published online on: 16 December 2025

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Article Open Access

Identifying myosin heavy chain 11 as a predictive biomarker of prostate cancer progression and antiandrogen resistance

Cong Chen, Zhi Li, Jianliang Shen, Guilin Xie, Liangming Pan
Article Number: 77
Published online on: 15 December 2025

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Retraction Open Access

[Retracted] Activation of GPER by E2 promotes proliferation, invasion and migration of breast cancer cells by regulating the miR‑124/CD151 pathway

Huaicheng Yang, Congyu Wang, Heqiang Liao, Qi Wang
Article Number: 76
Published online on: 15 December 2025

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Article Open Access

Identification of non‑oncology drugs with activity against inflammatory and triple‑negative breast cancer cell lines

Syed Ahmad, Sara Kandil, Kevin P. Williams, John E. Scott
Article Number: 75
Published online on: 15 December 2025

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Correction Open Access

[Corrigendum] Targeted silencing of CXCR4 inhibits epithelial‑mesenchymal transition in oral squamous cell carcinoma

Yuansheng Duan, Shu Zhang, Longlong Wang, Xuan Zhou, Qinghua He, Su Liu, Kai Yue, Xudong Wang
Article Number: 74
Published online on: 10 December 2025

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Case Report Open Access

Epstein‑Barr virus+ inflammatory follicular dendritic cell sarcoma with clonal immunoglobulin heavy chain gene rearrangement: A case report and literature review

Qian Ye, Juan Zhao, Jiao He, Weishan Zhang
Article Number: 73
Published online on: 09 December 2025

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A prognostic model for human papillomavirus‑negative head and neck squamous cell carcinoma based on a novel ferroptosis‑related gene signature: Development, validation and elucidation of its relationship with the immune microenvironment

Jiao Li, Nurhayu Ab Rahman, Suharni Mohamad, Guang Yang
Article Number: 72
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Knockdown of lncRNA NUTM2A‑AS1 inhibits lung adenocarcinoma cell viability by regulating the miR‑590‑5p/METTL3 axis

Jie Wang, Jingyun Zha, Xiaolin Wang
Article Number: 71
Published online on: 08 December 2025

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Case Report Open Access

Primary bone marrow diffuse large B‑cell lymphoma with secondary myelofibrosis: A case report

Jing Yang, Sheng-Ke Tu, Hui Peng, Yuan-Yuan Peng, Min Li, Kui Song
Article Number: 70
Published online on: 05 December 2025

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Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Article Open Access

Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Case Report Open Access

Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑Zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Review Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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