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Review

Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)

  • Authors:
    • Adeline Tintila
    • Bogdan Doroftei
    • Delia Grab
    • Gabriela Simionescu
    • Emil Anton
    • Radu Maftei
    • Ciprian Ilea
    • Carmen Anton
  • View Affiliations / Copyright

    Affiliations: Clinical Department, Spitalul Judetean Suceava, Suceava 720224, Romania, Department of Obstetrics and Gynecology, University of Medicine and Pharmacy ‘Grigore T. Popa’, Iasi 700115, Romania, Clinical Department, Sf. Spiridon Clinical Hospital, Iasi 700111, Romania
  • Article Number: 171
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    Published online on: January 4, 2021
       https://doi.org/10.3892/ol.2021.12432
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Abstract

Primitive neuroectodermal tumor (PNT) and Ewing's sarcoma are rare, round‑cell tumors, characterized by the presence of the t(11; 22)(q24; q12) chromosomal translocation. A review of the literature revealed only 38 previously reported cases of vulvar PNT and Ewing's sarcoma and 15 vaginal PNT and Ewing's sarcoma. Although rare, these types of tumors should be taken into consideration when making a differential diagnosis for vulvar or vaginal tumors. The currently available data is limited, and therefore, case reports are essential for improving knowledge and management of these types of extremely rare tumors. However, further molecular and histopathological studies are essential for an improved understanding of these conditions and for an early, correct diagnosis. Although the gathered and presented data from the present review are limited, the literature demonstrates that the outcome of these types of cancer are more favorable compared with outcomes observed for carcinomas in more typical locations.
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Copy and paste a formatted citation
Spandidos Publications style
Tintila A, Doroftei B, Grab D, Simionescu G, Anton E, Maftei R, Ilea C and Anton C: Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review). Oncol Lett 21: 171, 2021.
APA
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R. ... Anton, C. (2021). Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review). Oncology Letters, 21, 171. https://doi.org/10.3892/ol.2021.12432
MLA
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R., Ilea, C., Anton, C."Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)". Oncology Letters 21.2 (2021): 171.
Chicago
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R., Ilea, C., Anton, C."Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)". Oncology Letters 21, no. 2 (2021): 171. https://doi.org/10.3892/ol.2021.12432
Copy and paste a formatted citation
x
Spandidos Publications style
Tintila A, Doroftei B, Grab D, Simionescu G, Anton E, Maftei R, Ilea C and Anton C: Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review). Oncol Lett 21: 171, 2021.
APA
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R. ... Anton, C. (2021). Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review). Oncology Letters, 21, 171. https://doi.org/10.3892/ol.2021.12432
MLA
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R., Ilea, C., Anton, C."Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)". Oncology Letters 21.2 (2021): 171.
Chicago
Tintila, A., Doroftei, B., Grab, D., Simionescu, G., Anton, E., Maftei, R., Ilea, C., Anton, C."Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)". Oncology Letters 21, no. 2 (2021): 171. https://doi.org/10.3892/ol.2021.12432
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