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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2021 Volume 21 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Mutational characteristics of gastrointestinal stromal tumors: A single‑center analysis of 302 patients

Li Liang, Xin Li, Dong Li, Ping Liu, Lin Nong, Ying Dong, Jumei Liu, Sixia Huang, Ting Li
Article Number: 174
Published online on: 04 January 2021

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Review Open Access

Heparan sulfate proteoglycans and their modification as promising anticancer targets in hepatocellular carcinoma (Review)

Mohammed A. Alshehri, Moath M. Alshehri, Naif N. Albalawi, Moshari A. Al‑Ghamdi, Mohammed M.H. Al‑Gayyar
Article Number: 173
Published online on: 04 January 2021

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Article Open Access

Screening and validation of plasma long non‑coding RNAs as biomarkers for the early diagnosis and staging of oral squamous cell carcinoma

Hongcheng Jia, Xuan Wang, Zheng Sun
Article Number: 172
Published online on: 04 January 2021

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Review

Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)

Adeline Tintila, Bogdan Doroftei, Delia Grab, Gabriela Simionescu, Emil Anton, Radu Maftei, Ciprian Ilea, Carmen Anton
Article Number: 171
Published online on: 04 January 2021

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Article Open Access

Oral squamous cell carcinoma may originate from bone marrow‑derived stem cells

Tomonori Hasegawa, Koh-Ichi Nakashiro, Chonji Fukumoto, Toshiki Hyodo, Yuta Sawatani, Michiko Shimura, Ryouta Kamimura, Nobuyuki Kuribayashi, Atsushi Fujita, Daisuke Uchida, Hitoshi Kawamata
Article Number: 170
Published online on: 04 January 2021

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Article Open Access

Genomic characterization of clear cell renal cell carcinoma using targeted gene sequencing

Po-Hung Lin, Chao-Yuan Huang, Kai-Jie Yu, Hung-Cheng Kan, Chung-Yi Liu, Cheng-Keng Chuang, Yu-Chuan Lu, Ying-Hsu Chang, I-Hung Shao, See-Tong Pang
Article Number: 169
Published online on: 04 January 2021

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Article Open Access

Circulating plasma exosomal miRNA profiles serve as potential metastasis‑related biomarkers for hepatocellular carcinoma

Chunyu Huang, Shuiying Tang, Dong Shen, Xiangzhao  Li, Li Liang, Yanqing Ding, Bihong Xu
Article Number: 168
Published online on: 04 January 2021

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Article Open Access

Human giant larvae‑1 promotes migration and invasion of malignant glioma cells by regulating N‑cadherin

Yan Wang, Yu Zhang, Ben Sang, Xianlong Zhu, Rutong Yu, Xiuping Zhou
Article Number: 167
Published online on: 04 January 2021

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Review Open Access

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)

Yuelei Jin, Gangqiao Qi, Guang Chen, Chen Wang, Xiaoyan Fan
Article Number: 166
Published online on: 04 January 2021

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Article Open Access

Helicobacter pylori induces epithelial‑mesenchymal transition in gastric carcinogenesis via the AKT/GSK3β signaling pathway

Yaobin Ouyang, Gongmeizi Liu, Wenting Xu, Zhen Yang, Nianshuang Li, Chuan Xie, Chun Zhou, Jiang Chen, Yin Zhu, Junbo Hong, Nonghua Lu
Article Number: 165
Published online on: 04 January 2021

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Article Open Access

Expression of AMP‑activated protein kinase/ten‑eleven translocation 2 and their clinical relevance in colorectal cancer

Dong Hyun Kang, Dong Jun Jeong, Tae Sung Ahn, Hyun Yong Lee, Han Jo Kim, Sang Byung Bae, Hyeong Joo Kim, Moon Soo Lee, Hyog Young Kwon, Moo-Jun Baek
Article Number: 164
Published online on: 04 January 2021

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Article

Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases

Dana El‑Chami, Maria Al Haddad, Ralph Abi‑Habib, Mirvat El‑Sibai
Article Number: 163
Published online on: 31 December 2020

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Article

PRMT1 expression predicts sensitivity to platinum‑based chemotherapy in patients with ovarian serous carcinoma

Hiroaki Matsubara, Takeshi Fukuda, Yuichiro Awazu, Shigenori Nanno, Masahiro Shimomura, Yuta Inoue, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 162
Published online on: 31 December 2020

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Article Open Access

MicroRNA‑640 promotes cell proliferation and adhesion in glioblastoma by targeting Slit guidance ligand 1

Chao Luo, Zhiying Lu, Yongli Chen, Xiaozhen Chen, Na Liu, Jing Chen, Shanwu Dong
Article Number: 161
Published online on: 31 December 2020

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Article Open Access

Chemoradiotherapy alone vs. chemoradiotherapy and hysterectomy for locally advanced cervical cancer: A systematic review and updated meta‑analysis

Weijia Lu, Canxiong Lu, Zhiwu Yu, Lei Gao
Article Number: 160
Published online on: 31 December 2020

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Article Open Access

B3GNT3: A prognostic biomarker associated with immune cell infiltration in pancreatic adenocarcinoma

Kaiwen Kong, Yuanyu Zhao, Leilei Xia, Hui Jiang, Mingjuan Xu, Jianming Zheng
Article Number: 159
Published online on: 31 December 2020

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Article Open Access

Co‑localisation of intra‑nuclear membrane type‑1 matrix metalloproteinase and hypoxia inducible factor‑2α in osteosarcoma and prostate carcinoma cells

Corey D. Chan, Emma J. Haagensen, Hayeit A. Tensaout, Katherine J. Rennie, Zakareya Gamie, James Barry, Mark A. Birch, Craig H. Gerrand, Sohail Nisar, Craig N. Robson, John Lunec, Kenneth S. Rankin
Article Number: 158
Published online on: 31 December 2020

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Article Open Access

Long non‑coding RNA MIR22HG inhibits glioma progression by downregulating microRNA‑9/CPEB3

Yanli He, Haiyan Nan, Linfeng Yan, Tao Ma, Minghao Man, Bo Tian, Shaochun Guo, Xingye Zhang
Article Number: 157
Published online on: 31 December 2020

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Article

miR‑665 is downregulated in glioma and inhibits tumor cell proliferation, migration and invasion by targeting high mobility group box 1

Hao Shen, Ling Xu, Chunyue You, Huaibo Tang, Haitao Wu, Yong Zhang, Mingxiang Xie
Article Number: 156
Published online on: 31 December 2020

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Article Open Access

Hispidulin modulates epithelial‑mesenchymal transition in breast cancer cells

Hyun A. Kim, Joomin Lee
Article Number: 155
Published online on: 31 December 2020

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Article Open Access

Hsa_circ_0001696 modulates cell proliferation and migration in colorectal cancer

Pei-Fei Li, Zhi-Xin Zhang, Xin Yuan, Hao-Jun Song, Xiao-Yun Ding, Lei Xu
Article Number: 154
Published online on: 31 December 2020

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Article

Preoperative prognostic nutritional index predicts short‑ and long‑term outcomes after liver resection in patients with hepatocellular carcinoma

Yu Saito, Satoru Imura, Yuji Morine, Tetsuya Ikemoto, Shinichiro Yamada, Mitsuo Shimada
Article Number: 153
Published online on: 31 December 2020

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Article Open Access

miR‑128‑3p serves as an oncogenic microRNA in osteosarcoma cells by downregulating ZC3H12D

Maoshu Zhu, Yulong Wu, Zhaowei Wang, Minghua Lin, Bin Su, Chunyang Li, Fulong Liang, Xinjiang Chen
Article Number: 152
Published online on: 31 December 2020

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Article Open Access

Hereditary multiple osteochondromas in Jordanian patients: Mutational and immunohistochemical analysis of EXT1 and EXT2 genes

Ziyad Mohaidat, Khaldon Bodoor, Rowida Almomani, Mohammed Alorjani, Mohammad-Akram Awwad, Audai Bany‑Khalaf, Khalid Al‑Batayneh
Article Number: 151
Published online on: 30 December 2020

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Article Open Access

PRMT1 expression predicts response to neoadjuvant chemotherapy for locally advanced uterine cervical cancer

Masahiro Shimomura, Takeshi Fukuda, Yuichiro Awazu, Shigenori Nanno, Yuta Inoue, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 150
Published online on: 24 December 2020

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Review Open Access

Dual roles of myeloid‑derived suppressor cells induced by Toll‑like receptor signaling in cancer (Review)

Hongyue Zhou, Mengyu Jiang, Hongyan Yuan, Weihua Ni, Guixiang Tai
Article Number: 149
Published online on: 24 December 2020

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Review Open Access

Role of neutrophil gelatinase‑associated lipocalin in renal cell carcinoma (Review)

Kai Che, Wenkai Han, Mingxin Zhang, Haitao Niu
Article Number: 148
Published online on: 24 December 2020

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Article Open Access

MicroRNA‑206 inhibits the proliferation, migration and invasion of colorectal cancer cells by regulating the c‑Met/AKT/GSK‑3β pathway

Jiayu Lyu, Yao Sun, Xizhi Li, Huili Ma
Article Number: 147
Published online on: 23 December 2020

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Article Open Access

Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway

Dengdian Wang, Dongdong Xie, Liangkuan Bi, Yi Wang, Ci Zou, Lei Chen, Hao Geng, Weiwei Qian, Yuan Li, Hongliang Sun, Xin Wang, Youlu Lu, Dexin Yu, Caiyun Zhong
Article Number: 146
Published online on: 23 December 2020

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Article Open Access

P4HA1 regulates human colorectal cancer cells through HIF1α‑mediated Wnt signaling

Qiang Zhang, Yue Yin, Hongye Zhao, Yan Shi, Wei Zhang, Zhengpeng Yang, Tingting Liu, Yonghong Huang, Zhanjiang Yu
Article Number: 145
Published online on: 23 December 2020

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Article Open Access

Comprehensive analysis of lncRNA‑associated ceRNA network reveals the novel potential of lncRNA, miRNA and mRNA biomarkers in human rectosigmoid junction cancer

Qianshi Zhang, Zhen Feng, Shasha Shi, Yu Zhang, Shuangyi Ren
Article Number: 144
Published online on: 21 December 2020

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Article Open Access

L‑fucose ameliorates the carcinogenic properties of Fusobacterium nucleatum in colorectal cancer

Caihan Duan, Xuelian Tang, Weijun Wang, Wei Qian, Xiaochao Fu, Xiaohua Deng, Chaoqun Han, Xiaohua Hou
Article Number: 143
Published online on: 21 December 2020

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Article Open Access

Impact of chromosome 17 centromere copy number increase on patient survival and human epidermal growth factor receptor 2 expression in gastric adenocarcinoma

Maciej Ciesielski, Mariusz Szajewski, Jakub Walczak, Rafał  Pęksa, Radosław  Lenckowski, Małgorzata Supeł, Jacek  Zieliński, Wiesław Janusz Kruszewski
Article Number: 142
Published online on: 21 December 2020

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Article Open Access

Annexin A1 is a potential biomarker of bone metastasis in small cell lung cancer

Peng Chen, Jie Min, Hong Wu, Helong Zhang, Chaoli Wang, Guangguo Tan, Feng Zhang
Article Number: 141
Published online on: 20 December 2020

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Article Open Access

Influence of anaesthetics on the production of cancer cell motogens, stromal cell‑derived factor‑1 and hepatocyte growth factor by fibroblasts

Wenjing Gong, Tracey A. Martin, Andrew J. Sanders, Rachel Hargest, Aihua Jiang, Ping Sun, Wen G. Jiang
Article Number: 140
Published online on: 20 December 2020

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Article Open Access

MicroRNA‑7 modulates cellular senescence to relieve gemcitabine resistance by targeting PARP1/NF‑κB signaling in pancreatic cancer cells

Zhi-Qiang Ye, Han-Bin Chen, Tai-Yu Zhang, Zhi Chen, Ling Tian, Dian-Na Gu
Article Number: 139
Published online on: 20 December 2020

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Article Open Access

Transcriptome analysis and prognostic model construction based on splicing profiling in glioblastoma

Jiting Qiu, Chunhui Wang, Hongkang Hu, Sarah Chen, Xuehua Ding, Yu Cai
Article Number: 138
Published online on: 20 December 2020

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Article Open Access

MicroRNA‑200a and microRNA‑141 have a synergetic effect on the suppression of epithelial‑mesenchymal transition in liver cancer by targeting STAT4

Shuying Chen, Jingjun Zhang, Qiudan Chen, Juan Cheng, Xiaotong Chen, Yinqi Mao, Wei Chen, Chenbin Liu, Han Wu, Yuan Lv, Yong Lin
Article Number: 137
Published online on: 20 December 2020

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Review Open Access

Function of p21 and its therapeutic effects in esophageal cancer (Review)

Lei Wang, Huiqiong Han, Lin Dong, Zehua Wang, Yanru Qin
Article Number: 136
Published online on: 20 December 2020

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Correction Open Access

[Corrigendum] Focal adhesion kinase is involved in the migration of human osteosarcoma cells

Sitan Feng, Xin Shi, Ke Ren, Sujia Wu, Xiaoliang Sun
Article Number: 135
Published online on: 18 December 2020

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Correction Open Access

[Corrigendum] Overexpression of Notch1 is associated with the progression of cervical cancer

Yan Sun, Rui Zhang, Shujuan Zhou, Yuqiang Ji
Article Number: 134
Published online on: 18 December 2020

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Correction Open Access

[Corrigendum] miR-30d inhibits cell biological progression of Ewing’s sarcoma by suppressing the MEK/ERK and PI3K/Akt pathways in vitro

Conglin Ye, Xiaolong Yu, Xuqiang Liu, Min Dai, Bin Zhang
Article Number: 133
Published online on: 18 December 2020

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Article Open Access

Predictive value of baseline 18F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy

Lili Zhu, Yankai Meng, Lili Guo, Hanqing Zhao, Yue Shi, Shaodong Li, Anming Wang, Xiaojun Zhang, Jing Shi, Jie Zhu, Kai Xu
Article Number: 132
Published online on: 18 December 2020

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Article Open Access

Epidermal growth factor receptor intron 1 polymorphism and microsatellite instability in sporadic colorectal cancer

Sonja Marinović, Kristina Vuković, Anita Škrtić, Mirko Poljak, Sara Petek, Lara Petek, Sanja Kapitanović
Article Number: 131
Published online on: 18 December 2020

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Article Open Access

Long non‑coding RNA SNHG20 promotes ovarian cancer development by targeting microRNA‑338‑3p to regulate MCL1 expression

Ding Wang, Zhiying Li, Hui Li, Jiao Lu, Qi Qin
Article Number: 130
Published online on: 18 December 2020

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Article Open Access

Long non‑coding RNA T cell factor 7 is associated with increased disease risk and poor prognosis, and promotes cell proliferation, attenuates cell apoptosis and miR‑200c expression in multiple myeloma

Tianling Ding, Ruoyu Deng, Ting Huang
Article Number: 129
Published online on: 18 December 2020

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Article

Potential role of serum mesothelin in predicting survival of patients with malignant pleural mesothelioma

Vincenzo Fontana, Maria Pia Pistillo, Antonella Vigani, Pier Aldo Canessa, Giovanni Berisso, Ugo Giannoni, Paola Ferro, Maria Cristiana Franceschini, Roberta Carosio, Marika Tonarelli, Paolo Dessanti, Silvio Roncella
Article Number: 128
Published online on: 18 December 2020

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Article Open Access

Fucosylated C4b‑binding protein α‑chain, a novel serum biomarker that predicts lymph node metastasis in pancreatic ductal adenocarcinoma

Kazuyuki Sogawa, Sakino Yamanaka, Shigetsugu Takano, Kosuke Sasaki, Yoji Miyahara, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Hirotaka Takizawa, Fumio Nomura, Masayuki Ohtsuka
Article Number: 127
Published online on: 17 December 2020

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Article Open Access

Cytogenetic characteristics of 665 patients with myelodysplastic syndrome in China: A single‑center report

Xueying Wang, Weiyi Liu, Mingjing Wang, Teng Fan, Yumeng Li, Xiaoqing Guo, Xiupeng Yang, Hongzhi Wang, Haiyan Xiao, Shanshan Zhang, Richeng Quan, Chi Liu, Xudong Tang, Yan Lv, Zhuo Chen, Liu Li, Yonggang Xu, Rou Ma, Xiaomei Hu
Article Number: 126
Published online on: 17 December 2020

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Article Open Access

Comparative study of imaging and pathological evaluation of pneumonic mucinous adenocarcinoma

Jun Han, Chongchong Wu, Yuxin Wu, Hui Deng, Jie Gao, Hua Han, Xinying Xue
Article Number: 125
Published online on: 17 December 2020

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Article

Inhibition of mitochondrial and cytosolic calpain attenuates atrophy in myotubes co‑cultured with colon carcinoma cells

Xianliang Zeng, Li Zhao, Sizeng Chen, Xiantao Li
Article Number: 124
Published online on: 17 December 2020

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Article Open Access

MUC4 is a novel mediator in H. pylori infection‑related pancreatic cancer

Yu Gong, Shuai Chen, Yue Fu, Yu Liu, Yipeng Wang, Haojun Yang, Hanyang Liu, Liming Tang
Article Number: 123
Published online on: 17 December 2020

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Article Open Access

lncRNA SNHG3 acts as oncogene in ovarian cancer through miR‑139‑5p and Notch1 Corrigendum in /10.3892/ol.2025.15026

Li Zhang, Guihua Li, Xiuzhen Wang, Youli Zhang, Xia Huang, Huazhen Wu
Article Number: 122
Published online on: 17 December 2020

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Review Open Access

Human endogenous retroviruses in cancer: Expression, regulation and function (Review)

Yuan Gao, Xiao-Fang Yu, Ting Chen
Article Number: 121
Published online on: 17 December 2020

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Article

The importance of surgical margins in malignant Triton tumour of the trunk and extremities

Panagiotis Tsagozis, Czar Louie Gaston, Felix Haglund, Jan Balko, Vaiyapuri Sumathi, Robert Grimer, Michael Parry
Article Number: 120
Published online on: 15 December 2020

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Article

miR-21-5p promotes cell proliferation by targeting BCL11B in Thp-1 cells

Liang Zhang, Li Yu, Yiran Liu, Shasha Wang, Zhenfeng Hou, Jun Zhou
Article Number: 119
Published online on: 15 December 2020

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Article Open Access

Expression of TIPE family members in human colorectal cancer

Mengya Zhong, Zhijian Chen, Yang Yan, Argen Bahet, Xin Cai, Huiyu Chen, Honggang Ran, Kaiyong Qu, Zhaopu Han, Guohong Zhuang, Shifeng Zhang, Yinan Wang
Article Number: 118
Published online on: 15 December 2020

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Article Open Access

Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome

Yixian Liu, Qianwei Zhao, Fang Xu, Kaijuan Wang, Ying Zhao, Huiping Chen, Wei He, Weidong Wang, Jianying Zhang, Jintao Zhang
Article Number: 117
Published online on: 15 December 2020

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Article Open Access

Development of a prognostic model of glioma based on immune‑related genes

Jing-Jing Wang, Han Wang, Bao-Long Zhu, Xiang Wang, Yong-Hong Qian, Lei Xie, Wen-Jie Wang, Jie Zhu, Xing-Yu Chen, Jing-Mei Wang, Zhi-Liang Ding
Article Number: 116
Published online on: 15 December 2020

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Article Open Access

Molecular design and anti‑melanoma activity of a novel bullfrog antibacterial peptide RGD‑chimera

Mengyue Liu, Xuan Jiang, Chao Fu, Ruili Zhao, Tianming Jin, Jifei Ma, Shunyi Qin, Liu An Li, Ye Hu, Xin Zhang
Article Number: 115
Published online on: 15 December 2020

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Comparisons of ICG‑fluorescence with conventional tracers in sentinel lymph node biopsy for patients with early‑stage breast cancer: A meta‑analysis

Rui Yin, Lu-Yu Ding, Qing-Zhong Wei, Ya Zhou, Guang-Yuan Tang, Xun Zhu
Article Number: 114
Published online on: 15 December 2020

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Perphenazine exerts antitumor effects on HUT78 cells through Akt dephosphorylation by protein phosphatase 2A

Shunya Tsuji, Naoki Kohyanagi, Takuya Mizuno, Takashi Ohama, Koichi Sato
Article Number: 113
Published online on: 15 December 2020

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[Corrigendum] MicroRNA‑183‑5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells

Fei Miao, Jinhai Zhu, Yanlin Chen, Nanhong Tang, Xiaoqian Wang, Xiujin Li
Article Number: 112
Published online on: 14 December 2020

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[Corrigendum] Beclin‑1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK‑ES‑1 cells via inhibition of MMP‑9

Conglin Ye, Xiaolong Yu, Xuqiang Liu, Ping Zhan, Tao Nie, Runsheng Guo, Hucheng Liu, Min Dai, Bin Zhang
Article Number: 111
Published online on: 11 December 2020

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Review Open Access

Novel insights into the role of Clostridium novyi‑NT related combination bacteriolytic therapy in solid tumors (Review)

Xu Feng, Pan He, Chen Zeng, Ye-Han Li, Sushant K. Das, Bing Li, Han-Feng Yang, Yong Du
Article Number: 110
Published online on: 11 December 2020

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Inhibition of autophagy enhances apoptosis induced by bortezomib in AML cells

Lei Jiang, Yi-Ming Zhao, Ming-Zhen Yang
Article Number: 109
Published online on: 11 December 2020

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Breast cancer therapy affects the expression of antineonatal Nav1.5 antibodies in the serum of patients with breast cancer

Harishini Rajaratinam, Nur Syahmina Rasudin, Tengku Ahmad Damitri Al Astani, Noor Fatmawati Mokhtar, Maya Mazuwin Yahya, Wan Zainira Wan Zain, Nurul Asma‑Abdullah, Wan Ezumi Mohd Fuad
Article Number: 108
Published online on: 11 December 2020

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Anillin is a prognostic factor and is correlated with genovariation in pancreatic cancer based on databases analysis

Yuanhua Nie, Zhiqiang Zhao, Minxue Chen, Fulin Ma, Yong Fan, Yingxin Kang, Boxiong Kang, Chen Wang
Article Number: 107
Published online on: 10 December 2020

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Effects of dexmedetomidine on immune response in patients undergoing radical and reconstructive surgery for oral cancer

Lili Huang, Chuanqi Qin, Li Wang, Tiejun Zhang, Jianguo Li
Article Number: 106
Published online on: 10 December 2020

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Identification of LPCAT1 expression as a potential prognostic biomarker guiding treatment choice in acute myeloid leukemia

Ke Wang, Zhidan Wu, Yuan Si, Wendong Tang, Xin Xu, Yan Cheng, Jiang Lin
Article Number: 105
Published online on: 10 December 2020

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Construction and analysis of competing endogenous RNA network of MCF‑7 breast cancer cells based on the inhibitory effect of 6‑thioguanine on cell proliferation

Hao Li, Xinglan An, Qi Li, Hao Yu, Ziyi Li
Article Number: 104
Published online on: 10 December 2020

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MicroRNA‑15a‑5p promotes the proliferation and invasion of T98G glioblastoma cells via targeting cell adhesion molecule 1

Fanqiang Kong, Xiaoqing Li, Shuhong Li, Dan Sheng, Wenhu Li, Mingming Song
Article Number: 103
Published online on: 10 December 2020

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Comparison of the expression levels of lysine‑specific demethylase 1 and survival outcomes between triple‑negative and non‑triple‑negative breast cancer

Kangrong Zhao, Yanlin Li, Tiantian Han, Aiqin Sun, Wenxuan Bian, Mingyue Li, Qiong Lin, Genbao Shao
Article Number: 102
Published online on: 08 December 2020

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Isobaric tags for relative and absolute quantitation‑based proteomics analysis of the effect of ginger oil on bisphenol A‑induced breast cancer cell proliferation

Dan Lei, Tao Hong, Longxue Li, Lai Chen, Xiaoquan Luo, Qinghua Wu, Zhiyong Liu
Article Number: 101
Published online on: 08 December 2020

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Cardiotoxicity of anthracycline‑free targeted oncological therapies in HER2‑positive breast cancer (Review)

Jingyuan Guan, Mei Zhang
Article Number: 100
Published online on: 08 December 2020

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Oncolytic herpes simplex virus and temozolomide synergistically inhibit breast cancer cell tumorigenesis in vitro and in vivo

Jingjing Fan, Hua Jiang, Lin Cheng, Binlin Ma, Renbin Liu
Article Number: 99
Published online on: 08 December 2020

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Hypoxic exposure activates the B cell‑specific Moloney murine leukaemia virus integration site 1/PI3K/Akt axis and promotes EMT in leukaemia stem cells

Mingyan Jiang, Guoqian He, Jianhua Li, Jinrong Li, Xia Guo, Ju Gao
Article Number: 98
Published online on: 08 December 2020

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Article

Impact of Lin28 on lymph node metastasis in papillary thyroid carcinoma

Shuxun Jin, Chaoyang Xu, Linbo Wang, Jiangguo Wei, Songxiang Wang
Article Number: 97
Published online on: 07 December 2020

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Effect of let‑7c on the PI3K/Akt/FoxO signaling pathway in hepatocellular carcinoma

Yuehua Li, Pengfei Li, Na Wang
Article Number: 96
Published online on: 06 December 2020

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P4HB: A novel diagnostic and prognostic biomarker for bladder carcinoma

Yucai Wu, Yiji Peng, Bao Guan, Anbang He, Kunlin Yang, Shiming He, Yanqing Gong, Xuesong Li, Liqun Zhou
Article Number: 95
Published online on: 06 December 2020

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Genome‑wide prioritization reveals novel gene signatures associated with cardiotoxic effects of tyrosine kinase inhibitors

Yilan Li, Weijie Wang, Rong Gao, Xueming Xu, Yao Zhang
Article Number: 94
Published online on: 06 December 2020

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Downregulation of lysine‑specific demethylase 1 enhances the sensitivity of hormone‑sensitive prostate cancer cells to androgen deprivation therapy

Min Wang, Xiuheng Liu, Zhiyuan Chen, Lu Zhang, Xiaodong Weng
Article Number: 93
Published online on: 06 December 2020

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Increased fibrillarin expression is associated with tumor progression and an unfavorable prognosis in hepatocellular carcinoma

Jing Zhang, Gang Yang, Qiang Li, Fei Xie
Article Number: 92
Published online on: 06 December 2020

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Upregulation of miR-1307-3p and its function in the clinical prognosis and progression of gastric cancer

Yanhui Ma, Aifeng Zhou, Juan Song
Article Number: 91
Published online on: 06 December 2020

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Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat‑treated tumor cell lysates enhance antitumor activity in murine lung cancer

Huiguo Chen, Jianfeng Tan, Xiaojun Li, Hui Li, Weibin Wu, Yonghui Wu, Jian Zhang, Lijia Gu
Article Number: 90
Published online on: 06 December 2020

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Review Open Access

T lymphocytes related biomarkers for predicting immunotherapy efficacy in non‑small cell lung cancer (Review)

Xiaoying Wei, Ling Gu, Wei Heng
Article Number: 89
Published online on: 06 December 2020

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Article Open Access

MicroRNA‑633 enhances melanoma cell proliferation and migration by suppressing KAI1

Zhengxiang Wang, Yaling Liu
Article Number: 88
Published online on: 06 December 2020

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Long non‑coding RNA LINC00887 promotes progression of lung carcinoma by targeting the microRNA‑206/NRP1 axis

Ling-Bin Xu, Bian-Xin Bo, Jie Xiong, Ya-Juan Ren, Dong Han, Sheng-Hong Wei, Xiao-Ping Ren
Article Number: 87
Published online on: 06 December 2020

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LINC00488 stimulates the progression of esophageal cancer by targeting microRNA‑485‑5p Retraction in /10.3892/ol.2022.13412

Hongbo Xu, Yan Ye
Article Number: 86
Published online on: 04 December 2020

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Determination of FABP4, RBP4 and the MMP‑9/NGAL complex in the serum of women with breast cancer

Dimitris Tsakogiannis, Eleni Kalogera, Flora Zagouri, Eleni Zografos, Dimitris Balalis, Garyfalia Bletsa
Article Number: 85
Published online on: 04 December 2020

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Review

Biological effects of corosolic acid as an anti‑inflammatory, anti‑metabolic syndrome and anti‑neoplasic natural compound (Review)

Jinwei Zhao, Hong Zhou, Yanan An, Keshu Shen, Lu Yu
Article Number: 84
Published online on: 02 December 2020

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Correction Open Access

[Corrigendum] TGF‑β induces growth suppression in multiple myeloma MM.1S cells via E2F1

Xialei Liu, Hui Guo, Yuting Wei, Chaonong Cai, Baimeng Zhang, Jian Li
Article Number: 83
Published online on: 02 December 2020

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Atorvastatin potentiates the chemosensitivity of human liver cancer cells to cisplatin via downregulating YAP1

Liwen Guo, Jiaping Zheng, Hui Zeng, Zhewei Zhang, Guoliang Shao
Article Number: 82
Published online on: 01 December 2020

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Nuclear factor I/B mediates epithelial‑mesenchymal transition in human melanoma cells through ZEB1

Ruimin Cheng, Sheng Gao, Wei Hu, Yamei Liu, Yuchun Cao
Article Number: 81
Published online on: 01 December 2020

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Long non‑coding RNA SNHG9 inhibits ovarian cancer progression by sponging microRNA‑214‑5p

Gao-Yang Chen, Zhi-Sheng Zhang, Yu Chen, Yan Li
Article Number: 80
Published online on: 30 November 2020

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Abnormally high HIP1 expression is associated with metastatic behaviors and poor prognosis in ESCC

Ying Sun, Yongan Zhou, Jinghua Xia, Miaomiao Wen, Xuejiao Wang, Jiao Zhang, Yanning Zhang, Zhipei Zhang, Tao Jiang
Article Number: 79
Published online on: 30 November 2020

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Prognostic role of matrix metalloproteinase 9 in early breast cancer

Katarina Kalavska, Zuzana Cierna, Marian Karaba, Gabriel Minarik, Juraj Benca, Tatiana Sedlackova, Denisa Kolekova, Ivana Mrvova, Daniel Pindak, Jozef Mardiak, Michal Mego
Article Number: 78
Published online on: 30 November 2020

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Long non‑coding RNA AK001903 regulates tumor progression in cervical cancer

Guanglei Zhong, Xingyu Fang, Qingsheng Xie, Yuhan  Wang, Zhongqiu Lin, Rongchun Lin, Tingting Yao
Article Number: 77
Published online on: 30 November 2020

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Yuji Nitta, Tomoko Uchiyama, Akihiko Yoshizawa, Ryo Miyata, Masatsugu Hamaji, Hirotaka Kajihara, Masayuki Takeda
Article Number: 148
Published online on: 25 February 2026

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Gliosarcoma of the right cerebellar hemisphere and parahippocampal region: A case report and literature review

Fa Wu, Yulin Yang, Zaiqing Wang, Rui Jiang, Tingting Wu, Ting Yu, Peng Wang
Article Number: 147
Published online on: 25 February 2026

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Preliminary evidence for the integration of CNAs, CN‑LOH and mutational profiles into the prognostic stratification of elderly patients with NPM1‑mutated acute myeloid leukemia

Li Gao, Chunxia Zhang, Ming Gong, Zhengyi Cao, Chundi Liu, Sijie Wang, Zhenling Li
Article Number: 146
Published online on: 25 February 2026

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Pro‑tumourigenic effects of DCAF13 on the progression of colorectal cancer

Wenqi Zhang, Rongrong Zhang, Mengxuan Jia, Shuting Lan, Fangyuan Liu, Qin Jin, Liya Su, Gang Liu
Article Number: 145
Published online on: 25 February 2026

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Histone deacetylases: Function in tumor development and therapeutic prospects (Review)

Runling Lin, Yu Zhang, Hong Li, Fan Liang
Article Number: 144
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Role of EphA2‑PI3K signaling in vasculogenic mimicry induced by cancer‑associated fibroblasts in gastric cancer cells

Hee Sung Kim, You Jin Won, Ju Hee Shim, Hyun Ji Kim, Byung Sik Kim, Hea Nam Hong
Article Number: 143
Published online on: 24 February 2026

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Case Report

Gastric cancer in pregnancy: A case report

Jianhua Niu, Yan Gao, Yu Sun, Huixia Yang
Article Number: 142
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro

Giovanni Vanni Frajese, Monica Benvenuto, Massimo Fantini, Elena Ambrosin, Pamela Sacchetti, Laura Masuelli, Maria Gabriella Giganti, Andrea Modesti, Roberto Bei
Article Number: 141
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2

Fenmei Zhou, Juan Chen, Hairong Wang
Article Number: 140
Published online on: 16 February 2026

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Case Report Open Access

Penile metastasis from prostate cancer with CDK12 mutation: A case report and literature review

Qi Xiang, Yanwu Wang, Bin Yao, Huiwen Tang, Qiang Dang
Article Number: 139
Published online on: 16 February 2026

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Case Report

Successful treatment with tepotinib followed by pembrolizumab in pulmonary pleomorphic carcinoma harbouring a MET exon 14 skipping mutation: A case report

Susumu Tanaka, Yu Saida, Yumi Ando, Jun Arinami, Ryo Yamazaki, Tomoya Wakabayashi, Hiroki Watanabe, Kohei Kushiro, Ryo Suzuki, Naohiro Yanagimura, Masashi Arita, Miyuki Sato, Tomohiro Tanaka, Koichiro Nozaki, Satoshi Watanabe, Shuhei Kondo, Hajime Umezu, Toshiaki Kikuchi
Article Number: 138
Published online on: 12 February 2026

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Article Open Access

METTL5‑mediated m6A modification of 18S rRNA drives oral squamous cell carcinoma progression by enhancing CCND3 translation

Lianlian Liu, Surui Sheng, Xin Zheng, Shuojin Huang, Lu Wang, Dalong Shu, Leile Tang, Qianting He
Article Number: 137
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 136
Published online on: 12 February 2026

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Review Open Access

STOML2 promotes hepatocellular carcinoma cell proliferation, invasion and migration by activating the PI3K/AKT signaling pathway (Review)

Mengyan Li, Jianli Chen
Article Number: 135
Published online on: 11 February 2026

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Article

Fatty acid‑induced lipid accumulation promotes radiosensitization in Huh7 hepatocellular carcinoma cells

Haruto Tanaka, Yasushi Mariya, Satoru Monzen
Article Number: 134
Published online on: 11 February 2026

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Lactylation‑based machine algorithm combined with multi‑omics analysis to predict prognosis in cervical cancer

Ruyue Wang, Li Ning, Xiu Li, Yating Xu, Yu Si, Hongting Zhao, Qingling Ren
Article Number: 133
Published online on: 11 February 2026

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Potential treatment benefits of a GLP‑1R antagonist in combination with immune checkpoint inhibitors in colorectal cancer

Zengqin Zhan, Chuncha Zhan, Lianqiao Li, Dan Lan, Guya Meng, Fan Chen
Article Number: 132
Published online on: 10 February 2026

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Article

Effect of the hsa‑microRNA 200c‑3p/ZEB1 loop in epithelial‑mesenchymal transition of ovarian cancer cells

Merve Senturk, Ece Gumusoglu‑Acar, Samet Topuz, Tuba Gunel
Article Number: 131
Published online on: 10 February 2026

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Article Open Access

Inhibition of IRE1α kinase increases ferroptosis resistance in triple‑negative breast cancer cells

Shuo Xu, Si-Qi Yang
Article Number: 130
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS

Yi Xiao, Taoran Deng, Changliang Su, Zhen Shang
Article Number: 129
Published online on: 09 February 2026

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Case Report Open Access

Metastatic breast cancer in primary lung cancer with compound EGFR mutations: A case report

Tianyao Yang, Yifan Xu, Xi Lin, Guodong Chen, Fangfang Wang
Article Number: 128
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen, Jia Li
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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