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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February-2021 Volume 21 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Mutational characteristics of gastrointestinal stromal tumors: A single‑center analysis of 302 patients

Li Liang, Xin Li, Dong Li, Ping Liu, Lin Nong, Ying Dong, Jumei Liu, Sixia Huang, Ting Li
Article Number: 174
Published online on: 04 January 2021

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Review Open Access

Heparan sulfate proteoglycans and their modification as promising anticancer targets in hepatocellular carcinoma (Review)

Mohammed A. Alshehri, Moath M. Alshehri, Naif N. Albalawi, Moshari A. Al‑Ghamdi, Mohammed M.H. Al‑Gayyar
Article Number: 173
Published online on: 04 January 2021

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Article Open Access

Screening and validation of plasma long non‑coding RNAs as biomarkers for the early diagnosis and staging of oral squamous cell carcinoma

Hongcheng Jia, Xuan Wang, Zheng Sun
Article Number: 172
Published online on: 04 January 2021

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Review

Importance of studying primitive neuroectodermal tumors and extraosseous Ewing's sarcoma of the vagina and vulva (Review)

Adeline Tintila, Bogdan Doroftei, Delia Grab, Gabriela Simionescu, Emil Anton, Radu Maftei, Ciprian Ilea, Carmen Anton
Article Number: 171
Published online on: 04 January 2021

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Article Open Access

Oral squamous cell carcinoma may originate from bone marrow‑derived stem cells

Tomonori Hasegawa, Koh-Ichi Nakashiro, Chonji Fukumoto, Toshiki Hyodo, Yuta Sawatani, Michiko Shimura, Ryouta Kamimura, Nobuyuki Kuribayashi, Atsushi Fujita, Daisuke Uchida, Hitoshi Kawamata
Article Number: 170
Published online on: 04 January 2021

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Article Open Access

Genomic characterization of clear cell renal cell carcinoma using targeted gene sequencing

Po-Hung Lin, Chao-Yuan Huang, Kai-Jie Yu, Hung-Cheng Kan, Chung-Yi Liu, Cheng-Keng Chuang, Yu-Chuan Lu, Ying-Hsu Chang, I-Hung Shao, See-Tong Pang
Article Number: 169
Published online on: 04 January 2021

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Article Open Access

Circulating plasma exosomal miRNA profiles serve as potential metastasis‑related biomarkers for hepatocellular carcinoma

Chunyu Huang, Shuiying Tang, Dong Shen, Xiangzhao  Li, Li Liang, Yanqing Ding, Bihong Xu
Article Number: 168
Published online on: 04 January 2021

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Article Open Access

Human giant larvae‑1 promotes migration and invasion of malignant glioma cells by regulating N‑cadherin

Yan Wang, Yu Zhang, Ben Sang, Xianlong Zhu, Rutong Yu, Xiuping Zhou
Article Number: 167
Published online on: 04 January 2021

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Review Open Access

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)

Yuelei Jin, Gangqiao Qi, Guang Chen, Chen Wang, Xiaoyan Fan
Article Number: 166
Published online on: 04 January 2021

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Article Open Access

Helicobacter pylori induces epithelial‑mesenchymal transition in gastric carcinogenesis via the AKT/GSK3β signaling pathway

Yaobin Ouyang, Gongmeizi Liu, Wenting Xu, Zhen Yang, Nianshuang Li, Chuan Xie, Chun Zhou, Jiang Chen, Yin Zhu, Junbo Hong, Nonghua Lu
Article Number: 165
Published online on: 04 January 2021

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Article Open Access

Expression of AMP‑activated protein kinase/ten‑eleven translocation 2 and their clinical relevance in colorectal cancer

Dong Hyun Kang, Dong Jun Jeong, Tae Sung Ahn, Hyun Yong Lee, Han Jo Kim, Sang Byung Bae, Hyeong Joo Kim, Moon Soo Lee, Hyog Young Kwon, Moo-Jun Baek
Article Number: 164
Published online on: 04 January 2021

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Article

Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases

Dana El‑Chami, Maria Al Haddad, Ralph Abi‑Habib, Mirvat El‑Sibai
Article Number: 163
Published online on: 31 December 2020

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Article

PRMT1 expression predicts sensitivity to platinum‑based chemotherapy in patients with ovarian serous carcinoma

Hiroaki Matsubara, Takeshi Fukuda, Yuichiro Awazu, Shigenori Nanno, Masahiro Shimomura, Yuta Inoue, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 162
Published online on: 31 December 2020

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Article Open Access

MicroRNA‑640 promotes cell proliferation and adhesion in glioblastoma by targeting Slit guidance ligand 1

Chao Luo, Zhiying Lu, Yongli Chen, Xiaozhen Chen, Na Liu, Jing Chen, Shanwu Dong
Article Number: 161
Published online on: 31 December 2020

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Article Open Access

Chemoradiotherapy alone vs. chemoradiotherapy and hysterectomy for locally advanced cervical cancer: A systematic review and updated meta‑analysis

Weijia Lu, Canxiong Lu, Zhiwu Yu, Lei Gao
Article Number: 160
Published online on: 31 December 2020

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Article Open Access

B3GNT3: A prognostic biomarker associated with immune cell infiltration in pancreatic adenocarcinoma

Kaiwen Kong, Yuanyu Zhao, Leilei Xia, Hui Jiang, Mingjuan Xu, Jianming Zheng
Article Number: 159
Published online on: 31 December 2020

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Article Open Access

Co‑localisation of intra‑nuclear membrane type‑1 matrix metalloproteinase and hypoxia inducible factor‑2α in osteosarcoma and prostate carcinoma cells

Corey D. Chan, Emma J. Haagensen, Hayeit A. Tensaout, Katherine J. Rennie, Zakareya Gamie, James Barry, Mark A. Birch, Craig H. Gerrand, Sohail Nisar, Craig N. Robson, John Lunec, Kenneth S. Rankin
Article Number: 158
Published online on: 31 December 2020

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Article Open Access

Long non‑coding RNA MIR22HG inhibits glioma progression by downregulating microRNA‑9/CPEB3

Yanli He, Haiyan Nan, Linfeng Yan, Tao Ma, Minghao Man, Bo Tian, Shaochun Guo, Xingye Zhang
Article Number: 157
Published online on: 31 December 2020

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Article

miR‑665 is downregulated in glioma and inhibits tumor cell proliferation, migration and invasion by targeting high mobility group box 1

Hao Shen, Ling Xu, Chunyue You, Huaibo Tang, Haitao Wu, Yong Zhang, Mingxiang Xie
Article Number: 156
Published online on: 31 December 2020

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Article Open Access

Hispidulin modulates epithelial‑mesenchymal transition in breast cancer cells

Hyun A. Kim, Joomin Lee
Article Number: 155
Published online on: 31 December 2020

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Article Open Access

Hsa_circ_0001696 modulates cell proliferation and migration in colorectal cancer

Pei-Fei Li, Zhi-Xin Zhang, Xin Yuan, Hao-Jun Song, Xiao-Yun Ding, Lei Xu
Article Number: 154
Published online on: 31 December 2020

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Article

Preoperative prognostic nutritional index predicts short‑ and long‑term outcomes after liver resection in patients with hepatocellular carcinoma

Yu Saito, Satoru Imura, Yuji Morine, Tetsuya Ikemoto, Shinichiro Yamada, Mitsuo Shimada
Article Number: 153
Published online on: 31 December 2020

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Article Open Access

miR‑128‑3p serves as an oncogenic microRNA in osteosarcoma cells by downregulating ZC3H12D

Maoshu Zhu, Yulong Wu, Zhaowei Wang, Minghua Lin, Bin Su, Chunyang Li, Fulong Liang, Xinjiang Chen
Article Number: 152
Published online on: 31 December 2020

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Article Open Access

Hereditary multiple osteochondromas in Jordanian patients: Mutational and immunohistochemical analysis of EXT1 and EXT2 genes

Ziyad Mohaidat, Khaldon Bodoor, Rowida Almomani, Mohammed Alorjani, Mohammad-Akram Awwad, Audai Bany‑Khalaf, Khalid Al‑Batayneh
Article Number: 151
Published online on: 30 December 2020

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Article Open Access

PRMT1 expression predicts response to neoadjuvant chemotherapy for locally advanced uterine cervical cancer

Masahiro Shimomura, Takeshi Fukuda, Yuichiro Awazu, Shigenori Nanno, Yuta Inoue, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi
Article Number: 150
Published online on: 24 December 2020

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Review Open Access

Dual roles of myeloid‑derived suppressor cells induced by Toll‑like receptor signaling in cancer (Review)

Hongyue Zhou, Mengyu Jiang, Hongyan Yuan, Weihua Ni, Guixiang Tai
Article Number: 149
Published online on: 24 December 2020

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Review Open Access

Role of neutrophil gelatinase‑associated lipocalin in renal cell carcinoma (Review)

Kai Che, Wenkai Han, Mingxin Zhang, Haitao Niu
Article Number: 148
Published online on: 24 December 2020

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Article Open Access

MicroRNA‑206 inhibits the proliferation, migration and invasion of colorectal cancer cells by regulating the c‑Met/AKT/GSK‑3β pathway

Jiayu Lyu, Yao Sun, Xizhi Li, Huili Ma
Article Number: 147
Published online on: 23 December 2020

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Article Open Access

Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway

Dengdian Wang, Dongdong Xie, Liangkuan Bi, Yi Wang, Ci Zou, Lei Chen, Hao Geng, Weiwei Qian, Yuan Li, Hongliang Sun, Xin Wang, Youlu Lu, Dexin Yu, Caiyun Zhong
Article Number: 146
Published online on: 23 December 2020

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Article Open Access

P4HA1 regulates human colorectal cancer cells through HIF1α‑mediated Wnt signaling

Qiang Zhang, Yue Yin, Hongye Zhao, Yan Shi, Wei Zhang, Zhengpeng Yang, Tingting Liu, Yonghong Huang, Zhanjiang Yu
Article Number: 145
Published online on: 23 December 2020

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Article Open Access

Comprehensive analysis of lncRNA‑associated ceRNA network reveals the novel potential of lncRNA, miRNA and mRNA biomarkers in human rectosigmoid junction cancer

Qianshi Zhang, Zhen Feng, Shasha Shi, Yu Zhang, Shuangyi Ren
Article Number: 144
Published online on: 21 December 2020

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Article Open Access

L‑fucose ameliorates the carcinogenic properties of Fusobacterium nucleatum in colorectal cancer

Caihan Duan, Xuelian Tang, Weijun Wang, Wei Qian, Xiaochao Fu, Xiaohua Deng, Chaoqun Han, Xiaohua Hou
Article Number: 143
Published online on: 21 December 2020

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Article Open Access

Impact of chromosome 17 centromere copy number increase on patient survival and human epidermal growth factor receptor 2 expression in gastric adenocarcinoma

Maciej Ciesielski, Mariusz Szajewski, Jakub Walczak, Rafał  Pęksa, Radosław  Lenckowski, Małgorzata Supeł, Jacek  Zieliński, Wiesław Janusz Kruszewski
Article Number: 142
Published online on: 21 December 2020

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Article Open Access

Annexin A1 is a potential biomarker of bone metastasis in small cell lung cancer

Peng Chen, Jie Min, Hong Wu, Helong Zhang, Chaoli Wang, Guangguo Tan, Feng Zhang
Article Number: 141
Published online on: 20 December 2020

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Article Open Access

Influence of anaesthetics on the production of cancer cell motogens, stromal cell‑derived factor‑1 and hepatocyte growth factor by fibroblasts

Wenjing Gong, Tracey A. Martin, Andrew J. Sanders, Rachel Hargest, Aihua Jiang, Ping Sun, Wen G. Jiang
Article Number: 140
Published online on: 20 December 2020

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Article Open Access

MicroRNA‑7 modulates cellular senescence to relieve gemcitabine resistance by targeting PARP1/NF‑κB signaling in pancreatic cancer cells

Zhi-Qiang Ye, Han-Bin Chen, Tai-Yu Zhang, Zhi Chen, Ling Tian, Dian-Na Gu
Article Number: 139
Published online on: 20 December 2020

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Article Open Access

Transcriptome analysis and prognostic model construction based on splicing profiling in glioblastoma

Jiting Qiu, Chunhui Wang, Hongkang Hu, Sarah Chen, Xuehua Ding, Yu Cai
Article Number: 138
Published online on: 20 December 2020

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Article Open Access

MicroRNA‑200a and microRNA‑141 have a synergetic effect on the suppression of epithelial‑mesenchymal transition in liver cancer by targeting STAT4

Shuying Chen, Jingjun Zhang, Qiudan Chen, Juan Cheng, Xiaotong Chen, Yinqi Mao, Wei Chen, Chenbin Liu, Han Wu, Yuan Lv, Yong Lin
Article Number: 137
Published online on: 20 December 2020

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Review Open Access

Function of p21 and its therapeutic effects in esophageal cancer (Review)

Lei Wang, Huiqiong Han, Lin Dong, Zehua Wang, Yanru Qin
Article Number: 136
Published online on: 20 December 2020

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Correction Open Access

[Corrigendum] Focal adhesion kinase is involved in the migration of human osteosarcoma cells

Sitan Feng, Xin Shi, Ke Ren, Sujia Wu, Xiaoliang Sun
Article Number: 135
Published online on: 18 December 2020

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Correction Open Access

[Corrigendum] Overexpression of Notch1 is associated with the progression of cervical cancer

Yan Sun, Rui Zhang, Shujuan Zhou, Yuqiang Ji
Article Number: 134
Published online on: 18 December 2020

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Correction Open Access

[Corrigendum] miR-30d inhibits cell biological progression of Ewing’s sarcoma by suppressing the MEK/ERK and PI3K/Akt pathways in vitro

Conglin Ye, Xiaolong Yu, Xuqiang Liu, Min Dai, Bin Zhang
Article Number: 133
Published online on: 18 December 2020

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Article Open Access

Predictive value of baseline 18F‑FDG PET/CT and interim treatment response for the prognosis of patients with diffuse large B‑cell lymphoma receiving R‑CHOP chemotherapy

Lili Zhu, Yankai Meng, Lili Guo, Hanqing Zhao, Yue Shi, Shaodong Li, Anming Wang, Xiaojun Zhang, Jing Shi, Jie Zhu, Kai Xu
Article Number: 132
Published online on: 18 December 2020

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Article Open Access

Epidermal growth factor receptor intron 1 polymorphism and microsatellite instability in sporadic colorectal cancer

Sonja Marinović, Kristina Vuković, Anita Škrtić, Mirko Poljak, Sara Petek, Lara Petek, Sanja Kapitanović
Article Number: 131
Published online on: 18 December 2020

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Article Open Access

Long non‑coding RNA SNHG20 promotes ovarian cancer development by targeting microRNA‑338‑3p to regulate MCL1 expression

Ding Wang, Zhiying Li, Hui Li, Jiao Lu, Qi Qin
Article Number: 130
Published online on: 18 December 2020

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Article Open Access

Long non‑coding RNA T cell factor 7 is associated with increased disease risk and poor prognosis, and promotes cell proliferation, attenuates cell apoptosis and miR‑200c expression in multiple myeloma

Tianling Ding, Ruoyu Deng, Ting Huang
Article Number: 129
Published online on: 18 December 2020

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Article

Potential role of serum mesothelin in predicting survival of patients with malignant pleural mesothelioma

Vincenzo Fontana, Maria Pia Pistillo, Antonella Vigani, Pier Aldo Canessa, Giovanni Berisso, Ugo Giannoni, Paola Ferro, Maria Cristiana Franceschini, Roberta Carosio, Marika Tonarelli, Paolo Dessanti, Silvio Roncella
Article Number: 128
Published online on: 18 December 2020

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Article Open Access

Fucosylated C4b‑binding protein α‑chain, a novel serum biomarker that predicts lymph node metastasis in pancreatic ductal adenocarcinoma

Kazuyuki Sogawa, Sakino Yamanaka, Shigetsugu Takano, Kosuke Sasaki, Yoji Miyahara, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Hirotaka Takizawa, Fumio Nomura, Masayuki Ohtsuka
Article Number: 127
Published online on: 17 December 2020

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Article Open Access

Cytogenetic characteristics of 665 patients with myelodysplastic syndrome in China: A single‑center report

Xueying Wang, Weiyi Liu, Mingjing Wang, Teng Fan, Yumeng Li, Xiaoqing Guo, Xiupeng Yang, Hongzhi Wang, Haiyan Xiao, Shanshan Zhang, Richeng Quan, Chi Liu, Xudong Tang, Yan Lv, Zhuo Chen, Liu Li, Yonggang Xu, Rou Ma, Xiaomei Hu
Article Number: 126
Published online on: 17 December 2020

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Article Open Access

Comparative study of imaging and pathological evaluation of pneumonic mucinous adenocarcinoma

Jun Han, Chongchong Wu, Yuxin Wu, Hui Deng, Jie Gao, Hua Han, Xinying Xue
Article Number: 125
Published online on: 17 December 2020

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Article

Inhibition of mitochondrial and cytosolic calpain attenuates atrophy in myotubes co‑cultured with colon carcinoma cells

Xianliang Zeng, Li Zhao, Sizeng Chen, Xiantao Li
Article Number: 124
Published online on: 17 December 2020

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Article Open Access

MUC4 is a novel mediator in H. pylori infection‑related pancreatic cancer

Yu Gong, Shuai Chen, Yue Fu, Yu Liu, Yipeng Wang, Haojun Yang, Hanyang Liu, Liming Tang
Article Number: 123
Published online on: 17 December 2020

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Article Open Access

lncRNA SNHG3 acts as oncogene in ovarian cancer through miR‑139‑5p and Notch1 Corrigendum in /10.3892/ol.2025.15026

Li Zhang, Guihua Li, Xiuzhen Wang, Youli Zhang, Xia Huang, Huazhen Wu
Article Number: 122
Published online on: 17 December 2020

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Review Open Access

Human endogenous retroviruses in cancer: Expression, regulation and function (Review)

Yuan Gao, Xiao-Fang Yu, Ting Chen
Article Number: 121
Published online on: 17 December 2020

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Article

The importance of surgical margins in malignant Triton tumour of the trunk and extremities

Panagiotis Tsagozis, Czar Louie Gaston, Felix Haglund, Jan Balko, Vaiyapuri Sumathi, Robert Grimer, Michael Parry
Article Number: 120
Published online on: 15 December 2020

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Article

miR-21-5p promotes cell proliferation by targeting BCL11B in Thp-1 cells

Liang Zhang, Li Yu, Yiran Liu, Shasha Wang, Zhenfeng Hou, Jun Zhou
Article Number: 119
Published online on: 15 December 2020

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Article Open Access

Expression of TIPE family members in human colorectal cancer

Mengya Zhong, Zhijian Chen, Yang Yan, Argen Bahet, Xin Cai, Huiyu Chen, Honggang Ran, Kaiyong Qu, Zhaopu Han, Guohong Zhuang, Shifeng Zhang, Yinan Wang
Article Number: 118
Published online on: 15 December 2020

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Article Open Access

Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome

Yixian Liu, Qianwei Zhao, Fang Xu, Kaijuan Wang, Ying Zhao, Huiping Chen, Wei He, Weidong Wang, Jianying Zhang, Jintao Zhang
Article Number: 117
Published online on: 15 December 2020

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Article Open Access

Development of a prognostic model of glioma based on immune‑related genes

Jing-Jing Wang, Han Wang, Bao-Long Zhu, Xiang Wang, Yong-Hong Qian, Lei Xie, Wen-Jie Wang, Jie Zhu, Xing-Yu Chen, Jing-Mei Wang, Zhi-Liang Ding
Article Number: 116
Published online on: 15 December 2020

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Article Open Access

Molecular design and anti‑melanoma activity of a novel bullfrog antibacterial peptide RGD‑chimera

Mengyue Liu, Xuan Jiang, Chao Fu, Ruili Zhao, Tianming Jin, Jifei Ma, Shunyi Qin, Liu An Li, Ye Hu, Xin Zhang
Article Number: 115
Published online on: 15 December 2020

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[Corrigendum] MicroRNA‑183‑5p promotes the proliferation, invasion and metastasis of human pancreatic adenocarcinoma cells

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Published online on: 14 December 2020

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[Corrigendum] Beclin‑1 knockdown decreases proliferation, invasion and migration of Ewing sarcoma SK‑ES‑1 cells via inhibition of MMP‑9

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Article Number: 100
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Published online on: 07 December 2020

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Yuehua Li, Pengfei Li, Na Wang
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Min Wang, Xiuheng Liu, Zhiyuan Chen, Lu Zhang, Xiaodong Weng
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Jing Zhang, Gang Yang, Qiang Li, Fei Xie
Article Number: 92
Published online on: 06 December 2020

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Yanhui Ma, Aifeng Zhou, Juan Song
Article Number: 91
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Myeloid and plasmacytoid dendritic cell combined vaccines loaded with heat‑treated tumor cell lysates enhance antitumor activity in murine lung cancer

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Published online on: 06 December 2020

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Xiaoying Wei, Ling Gu, Wei Heng
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Zhengxiang Wang, Yaling Liu
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Hongbo Xu, Yan Ye
Article Number: 86
Published online on: 04 December 2020

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Dimitris Tsakogiannis, Eleni Kalogera, Flora Zagouri, Eleni Zografos, Dimitris Balalis, Garyfalia Bletsa
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Jinwei Zhao, Hong Zhou, Yanan An, Keshu Shen, Lu Yu
Article Number: 84
Published online on: 02 December 2020

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[Corrigendum] TGF‑β induces growth suppression in multiple myeloma MM.1S cells via E2F1

Xialei Liu, Hui Guo, Yuting Wei, Chaonong Cai, Baimeng Zhang, Jian Li
Article Number: 83
Published online on: 02 December 2020

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Atorvastatin potentiates the chemosensitivity of human liver cancer cells to cisplatin via downregulating YAP1

Liwen Guo, Jiaping Zheng, Hui Zeng, Zhewei Zhang, Guoliang Shao
Article Number: 82
Published online on: 01 December 2020

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Nuclear factor I/B mediates epithelial‑mesenchymal transition in human melanoma cells through ZEB1

Ruimin Cheng, Sheng Gao, Wei Hu, Yamei Liu, Yuchun Cao
Article Number: 81
Published online on: 01 December 2020

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Long non‑coding RNA SNHG9 inhibits ovarian cancer progression by sponging microRNA‑214‑5p

Gao-Yang Chen, Zhi-Sheng Zhang, Yu Chen, Yan Li
Article Number: 80
Published online on: 30 November 2020

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Abnormally high HIP1 expression is associated with metastatic behaviors and poor prognosis in ESCC

Ying Sun, Yongan Zhou, Jinghua Xia, Miaomiao Wen, Xuejiao Wang, Jiao Zhang, Yanning Zhang, Zhipei Zhang, Tao Jiang
Article Number: 79
Published online on: 30 November 2020

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Prognostic role of matrix metalloproteinase 9 in early breast cancer

Katarina Kalavska, Zuzana Cierna, Marian Karaba, Gabriel Minarik, Juraj Benca, Tatiana Sedlackova, Denisa Kolekova, Ivana Mrvova, Daniel Pindak, Jozef Mardiak, Michal Mego
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Published online on: 30 November 2020

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Long non‑coding RNA AK001903 regulates tumor progression in cervical cancer

Guanglei Zhong, Xingyu Fang, Qingsheng Xie, Yuhan  Wang, Zhongqiu Lin, Rongchun Lin, Tingting Yao
Article Number: 77
Published online on: 30 November 2020

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

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SCImago Journal Rank (SJR): 0.663

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TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
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Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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