Open Access

Role of exosomes in pancreatic cancer (Review)

  • Authors:
    • Hao Liu
    • Shishi Qiao
    • Xiaoyue Fan
    • Yufei Gu
    • Yingxuan Zhang
    • Shuai Huang
  • View Affiliations

  • Published online on: February 17, 2021     https://doi.org/10.3892/ol.2021.12559
  • Article Number: 298
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Pancreatic cancer (PC) is a malignant tumour of the human digestive system that has a poor prognosis. Exosomes contain proteins and nucleic acids, and constitute a class of extracellular vesicles defined as membrane‑bound nanovesicles of endocytic origin, with a diameter of 40‑150 nm. Exosomes are potential diagnostic markers of PC; however, their roles in cancer initiation and progression remain unclear. Previous studies have focused on the molecular mechanisms and functions of exosomes that allow them to accelerate PC cell proliferation, migration and invasion. The present review discusses the interactions between exosomes and the pathophysiology of PC. The potential clinical applications of exosomes are also discussed.
View Figures
View References

Related Articles

Journal Cover

April-2021
Volume 21 Issue 4

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Liu H, Qiao S, Fan X, Gu Y, Zhang Y and Huang S: Role of exosomes in pancreatic cancer (Review). Oncol Lett 21: 298, 2021
APA
Liu, H., Qiao, S., Fan, X., Gu, Y., Zhang, Y., & Huang, S. (2021). Role of exosomes in pancreatic cancer (Review). Oncology Letters, 21, 298. https://doi.org/10.3892/ol.2021.12559
MLA
Liu, H., Qiao, S., Fan, X., Gu, Y., Zhang, Y., Huang, S."Role of exosomes in pancreatic cancer (Review)". Oncology Letters 21.4 (2021): 298.
Chicago
Liu, H., Qiao, S., Fan, X., Gu, Y., Zhang, Y., Huang, S."Role of exosomes in pancreatic cancer (Review)". Oncology Letters 21, no. 4 (2021): 298. https://doi.org/10.3892/ol.2021.12559