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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2021 Volume 21 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological and immunohistochemical characteristics of pigmented oral squamous cell carcinoma

Cuong Minh Tran, Takeshi Kuroshima, Yu Oikawa, Yasuyuki Michi, Kou Kayamori, Hiroyuki Harada
Article Number: 339
Published online on: 26 February 2021

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Article

Dorsal root ganglia NR2B‑mediated Epac1‑Piezo2 signaling pathway contributes to mechanical allodynia of bone cancer pain

Kun Ni, Wei Zhang, Yuan Ni, Yan-Ting Mao, Yi Wang, Xiao-Ping Gu, Zheng-Liang Ma
Article Number: 338
Published online on: 26 February 2021

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Article Open Access

A combination of sorafenib and radiotherapy reduces NF‑κB activity and growth of hepatocellular carcinoma in an orthotopic mouse model

Hui-Yen Chuang, Yeu-Sheng Tyan, Jeng-Jong Hwang, Kuang-Chung Shih, Wei-Chan Lin
Article Number: 337
Published online on: 26 February 2021

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Review Open Access

Genomics and transcriptomics in veterinary oncology (Review)

Bridget Marie Harrison, Panayiotis Loukopoulos
Article Number: 336
Published online on: 26 February 2021

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Article Open Access

Miconazole induces autophagic death in glioblastoma cells via reactive oxygen species‑mediated endoplasmic reticulum stress

Hui-Jung Jung, Incheol Seo, Bijay Kumar Jha, Seong-Il Suh, Won-Ki Baek
Article Number: 335
Published online on: 25 February 2021

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Article Open Access

MYG1 promotes proliferation and inhibits autophagy in lung adenocarcinoma cells via the AMPK/mTOR complex 1 signaling pathway

Xiaodan Han, Aili Li, Wei Wang, Longxia Du, Chen Wang, Guojin Huang
Article Number: 334
Published online on: 25 February 2021

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Review

Role of MALAT1 in gynecological cancers: Pathologic and therapeutic aspects (Review)

Feng-Hua Qiao, Min Tu, Hong-Yan Liu
Article Number: 333
Published online on: 25 February 2021

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Article Open Access

Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 332
Published online on: 25 February 2021

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Article Open Access

Altered expression of striatin‑4 is associated with poor prognosis in bladder transitional cell carcinoma

Yuhan Zhang, Xinquan Gu, Fuquan Jiang, Pinghui Sun, Xu Li
Article Number: 331
Published online on: 25 February 2021

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Article Open Access

Methyltransferase‑like 1 regulates lung adenocarcinoma A549 cell proliferation and autophagy via the AKT/mTORC1 signaling pathway

Chen Wang, Wei Wang, Xiaodan Han, Longxia Du, Aili Li, Guojin Huang
Article Number: 330
Published online on: 25 February 2021

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Article Open Access

Clinicopathological and molecular characteristics of patients with hypermutant lung cancer: A retrospective cohort study

Hongbin Zhang, Yuan Wang, Qiaoxia Ji, Hongmei Cai, Xiangcun Liang, Jiong Xie, Hua Li, Jun Wang, Guiyun Zhu, Erpeng Tian, Lingling Zhu, Mingming Yuan, Rongrong Chen, Min Zhao
Article Number: 329
Published online on: 25 February 2021

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Article Open Access

Forkhead box protein O3a promotes glioma cell resistance to temozolomide by regulating matrix metallopeptidase and β‑catenin

Datong Sun, Shenghui Yang, Xufeng Zhang, Sai Li, Lin Wang, Junmin Chen, Chun Qiu, Ke Xu
Article Number: 328
Published online on: 25 February 2021

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Article Open Access

MicroRNA‑1301‑3p promotes the progression of non‑small cell lung cancer by targeting Thy‑1 and predicts poor prognosis of patients

Ling Xu, Na Ni, Haiyang Gao, Pengbo Hu
Article Number: 327
Published online on: 24 February 2021

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Article Open Access

Four potential microRNAs affect the progression of pancreatic ductal adenocarcinoma by targeting MET via the PI3K/AKT signaling pathway

Li-Chao Yao, Xiu-Hua Jiang, Si-Si Yan, Wei Wang, Lun Wu, Lu-Lu  Zhai, Feng Xiang, Tao Ji, Lin Ye, Zhi-Gang Tang
Article Number: 326
Published online on: 24 February 2021

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Article Open Access

Expression of immune check point gene TIM‑3 in patients newly diagnosed with acute myeloid leukemia: Significance and impact on outcome

Amany M. Kamal, Nermeen A. Nabih, Nooran S. Elleboudy, Sara M. Radwan
Article Number: 325
Published online on: 24 February 2021

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Review

MicroRNA polymorphism: A target for diagnosis and prognosis of hepatocellular carcinoma? (Review)

Ruixia Ma, Maomao Zhao, Xin Zou, Jianye Zhou, Zhongtian Bai
Article Number: 324
Published online on: 24 February 2021

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Article Open Access

NCAPG upregulation mediated by four microRNAs combined with activation of the p53 signaling pathway is a predictor of poor prognosis in patients with breast cancer

Menglu Dong, Tao Xu, Xiaoqing Cui, Hanning Li, Xingrui Li, Wenfei Xia
Article Number: 323
Published online on: 23 February 2021

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Article Open Access

High expression of regulator of G‑protein signalling 1 is associated with the poor differentiation and prognosis of gastric cancer

Shilong Li, Huaxiang Yang, Shuliang Li, Zongxian Zhao, Daohan Wang, Weihua Fu
Article Number: 322
Published online on: 23 February 2021

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Article Open Access

Network pharmacology‑based study to explore the mechanism of the Yiqi Gubiao pill in lung cancer treatment

Zheng Li, Dan Xu, Jing Jing, Fengsen Li
Article Number: 321
Published online on: 23 February 2021

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Article

Integrin‑linked kinase pathway in heterogeneous pulmonary sarcomatoid carcinoma

Shigeki Shimizu, Kazuko Sakai, Takaaki Chikugo, Takao Satou, Naoki Shiraishi, Tetsuya Mitsudomi, Kazuto Nishio
Article Number: 320
Published online on: 23 February 2021

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Article Open Access

A nomogram combining PPARγ expression profiles and clinical factors predicts survival in patients with hepatocellular carcinoma

Xiaolu Zhou, Yajing Chi, Zhiyuan Dong, Tao Tao, Xin  Zhang, Wensheng Pan, Yemeng Wang
Article Number: 319
Published online on: 23 February 2021

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Review Open Access

Human cytomegalovirus infection: A considerable issue following allogeneic hematopoietic stem cell transplantation (Review)

Xinyi Zhou, Nan Jin, Baoan Chen
Article Number: 318
Published online on: 23 February 2021

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Review Open Access

New progress in the study of germline susceptibility genes of myeloid neoplasms (Review)

Lei Bi, Tianyuan Ma, Xu Li, Lai Wei, Zinuo Liu, Bingyue Feng, Baoxia Dong, Xiequn Chen
Article Number: 317
Published online on: 23 February 2021

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Review Open Access

Role of the long non‑coding RNA LINC00052 in tumors (Review)

Dongmei Xiong, Dan Wang, Yanmeng Chen
Article Number: 316
Published online on: 23 February 2021

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Review Open Access

Clinical significance of hypertension in patients with different types of cancer treated with antiangiogenic drugs (Review)

Mei Dong, Rujian Wang, Ping Sun, Dongxia Zhang, Zhenzhen  Zhang, Jing Zhang, Gary Tse, Lin Zhong
Article Number: 315
Published online on: 23 February 2021

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Article Open Access

Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 314
Published online on: 23 February 2021

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Review Open Access

Hippo/TEAD4 signaling pathway as a potential target for the treatment of breast cancer (Review)

Yujian Wu, Mengjie Li, Jiayi Lin, Chenxia Hu
Article Number: 313
Published online on: 23 February 2021

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Article Open Access

YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway

Linhua Jiang, Jiawen Zhang, Qixuan Xu, Bin Wang, Yizhou Yao, Liang Sun, Xuchao Wang, Diyuan Zhou, Ling Gao, Shiduo Song, Xinguo Zhu
Article Number: 312
Published online on: 23 February 2021

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Correction Open Access

[Corrigendum] Clinical analysis of 21-gene relapse score test in hormone receptor-positive early-stage breast cancer

Lizhe Zhu, Nan Ma, Bin Wang, Can Zhou, Yu Yan, Ke Wang, Jianjun He, Yu Ren
Article Number: 311
Published online on: 23 February 2021

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Article Open Access

MicroRNA‑15a‑5p inhibits endometrial carcinoma proliferation, invasion and migration via downregulation of VEGFA and inhibition of the Wnt/β‑catenin signaling pathway

Honggang Wang, Qingju Yang, Jieping Li, Wenping Chen, Xiao Jin, Yaowen Wang
Article Number: 310
Published online on: 22 February 2021

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Review

Deciphering the structure, function, expression and regulation of aquaporin‑5 in cancer evolution (Review)

Liping Wang, Da Huo, Haiyan Zhu, Qian Xu, Chengpeng Gao, Wenfeng Chen, Yixiang Zhang
Article Number: 309
Published online on: 21 February 2021

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Review Open Access

Organoid research in digestive system tumors (Review)

Xiaoxiao Yang, Xuewen Xu, Haitao Zhu, Ming Wang, Dongqing Wang
Article Number: 308
Published online on: 21 February 2021

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Article

Expression of canonical transient receptor potential channels in U-2 OS and MNNG-HOS osteosarcoma cell lines

Florian Lässig, Anja Klann, Sander Bekeschus, Uwe Lendeckel, Carmen Wolke
Article Number: 307
Published online on: 21 February 2021

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Article Open Access

Targeting SIRT1 to inhibit the proliferation of multiple myeloma cells

Bo Lu, Dengyang Zhang, Xiaobo Wang, Dongjun Lin, Yun Chen, Xiaojun Xu
Article Number: 306
Published online on: 21 February 2021

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Article Open Access

Effects of targeted Notch1 silencing on the biological processes of the T24 and 5637 cells in vitro

Kewen Zheng, Xiaomin Han, Yan Su, Qinghai Wang, Qiang Ma, Kesi Zheng
Article Number: 305
Published online on: 21 February 2021

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Article

EGR‑1 plays a protective role in AMPK inhibitor compound C‑induced apoptosis through ROS‑induced ERK activation in skin cancer cells

Kai-Cheng Chuang, Fan-Wen Chen, Meng-Hsiun Tsai, Jeng-Jer Shieh
Article Number: 304
Published online on: 19 February 2021

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Article Open Access

Notch intracellular domain regulates glioblastoma proliferation through the Notch1 signaling pathway

Yixuan Wang, Qian Sun, Rongxin Geng, Hao Liu, Fan'en Yuan, Yang Xu, Yangzhi Qi, Hongxiang Jiang, Qianxue Chen, Baohui Liu
Article Number: 303
Published online on: 19 February 2021

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Review Open Access

The HOTAIR lncRNA: A remarkable oncogenic promoter in human cancer metastasis (Review)

Lili Chen, Xinle Qian, Zhongqi Wang, Xiqiu Zhou
Article Number: 302
Published online on: 17 February 2021

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Article Open Access

Nuclear factor‑κB inhibitor Bay11‑7082 inhibits gastric cancer cell proliferation by inhibiting Gli1 expression

Yan Yan, Heya Qian, Ying Cao, Tao Zhu
Article Number: 301
Published online on: 17 February 2021

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Article Open Access

miR-153 enhances the therapeutic effect of radiotherapy by targeting JAG1 in pancreatic cancer cells

Zhibin Zhao, Xiaoxue Shen, Dongli Zhang, Hongmei Xiao, Hongfang Kong, Bin Yang, Li Yang
Article Number: 300
Published online on: 17 February 2021

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Article Open Access

Curcumol inhibits the viability and invasion of colorectal cancer cells via miR‑30a‑5p and Hippo signaling pathway

Dan Yu, Haiping Liu, Jianli Qin, Mengjie Huangfu, Xiao Guan, Xumei Li, Luwei Zhou, Tong Dou, Yisa Liu, Lin Wang, Minglei Fu, Juan Wang, Xu Chen
Article Number: 299
Published online on: 17 February 2021

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Review Open Access

Role of exosomes in pancreatic cancer (Review)

Hao Liu, Shishi Qiao, Xiaoyue Fan, Yufei Gu, Yingxuan Zhang, Shuai Huang
Article Number: 298
Published online on: 17 February 2021

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Article Open Access

FAM83A and FAM83A‑AS1 both play oncogenic roles in lung adenocarcinoma

Gaoming Wang, Xiaokun Li, Yu Yao, Zhisheng Jiang, Hai Zhou, Kai Xie, Jing Luo, Yi Shen
Article Number: 297
Published online on: 17 February 2021

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Article Open Access

PFKFB4 as a promising biomarker to predict a poor prognosis in patients with gastric cancer

Fang Wang, Xiaoting Wu, Yajun Li, Xiangmei Cao, Cao Zhang, Yujing Gao
Article Number: 296
Published online on: 17 February 2021

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Article

Cyclopamine sensitizes multiple myeloma cells to circularly permuted TRAIL‑induced apoptosis

Huijuan Wang, Chuanying Geng, Huixing Zhou, Zhiyao Zhang, Wenming Chen
Article Number: 295
Published online on: 17 February 2021

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Article Open Access

Inhibition of platelet‑derived growth factor receptor synergistically increases the pharmacological effect of tamoxifen in estrogen receptor α positive breast cancer

Sangmin Kim, Daeun You, Yisun Jeong, Sun Young Yoon, Sung A Kim, Jeong Eon Lee
Article Number: 294
Published online on: 17 February 2021

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Article Open Access

Sirtuin 6 regulates the proliferation and survival of clear cell renal cell carcinoma cells via B‑cell lymphoma 2

Jun An, Jieping Yang, Yang Yao, Kaining Lu, Zhiqiang Zhao, Meng Yu, Yuyan Zhu
Article Number: 293
Published online on: 17 February 2021

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Article Open Access

Salidroside and isorhamnetin attenuate urotensin II‑induced inflammatory response in vivo and in vitro: Involvement in regulating the RhoA/ROCK II pathway

Chenjing Wang, Xiaodong Nan, Shuyan Pei, Yu Zhao, Xiaokun Wang, Shijie Ma, Guoyan Ma
Article Number: 292
Published online on: 17 February 2021

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Correction Open Access

[Corrigendum] Effects of HPV16E6 transfection on the biological behavior of Eca109 and Eca9706 cells

Xin-Dan Kang, Yong Zheng, Wei-Gang Chen, Min Cheng, Di Zhang
Article Number: 291
Published online on: 15 February 2021

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Correction Open Access

[Corrigendum] Ceramide synthase‑4 orchestrates the cell proliferation and tumor growth of liver cancer in vitro and in vivo through the nuclear factor‑κB signaling pathway

Jinwu Chen, Xiaojie Li, Dengjiao Ma, Tao Liu, Pingping Tian, Chuanfang Wu
Article Number: 290
Published online on: 15 February 2021

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Article Open Access

PSMC2, ORC5 and KRTDAP are specific biomarkers for HPV‑negative head and neck squamous cell carcinoma

Yushen Su, Zhirui Zeng, Dongyun Rong, Yushi Yang, Bei Wu, Yu Cao
Article Number: 289
Published online on: 12 February 2021

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Article Open Access

lncRNA UASR1 is overexpressed in oral squamous cell carcinoma and regulates cancer cell proliferation by regulating miR‑375/JAK2 axis

Yugang Sun, Liang Chen, Lina Pan
Article Number: 288
Published online on: 12 February 2021

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Review

The changing treatment of metastatic her2‑positive breast cancer (Review)

Maria Mitsogianni, Ioannis P. Trontzas, Georgia Gomatou, Stephanie Ioannou, Nikolaos K. Syrigos, Elias A. Kotteas
Article Number: 287
Published online on: 12 February 2021

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Article Open Access

Curcumin inhibits the growth of liver cancer by impairing myeloid‑derived suppressor cells in murine tumor tissues

Sha Tian, Liu Liao, Qing Zhou, Xiaodi Huang, Piao Zheng, Yinmei Guo, Tianhao Deng, Xuefei Tian
Article Number: 286
Published online on: 12 February 2021

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Article Open Access

In vivo, ex vivo and in vitro dasatinib activity in chronic lymphocytic leukemia

Krzysztof Giannopoulos, Agnieszka Karczmarczyk, Marta Karp, Agnieszka Bojarska‑Junak, Kamila Kosior, Małgorzata Kowal, Waldemar Tomczak, Marek Hus, Marcin Machnicki, Tomasz Stokłosa
Article Number: 285
Published online on: 12 February 2021

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Article Open Access

The effect of the area proportion of the metastatic lesion within the central metastatic lymph node on response to therapy in papillary thyroid carcinoma

Liuhong Shi, Liang Zhou, Jianbiao Wang, Lei Jin, Yinjiao Lei, Lian Xia, Lei Xie
Article Number: 284
Published online on: 12 February 2021

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Article Open Access

Exosomal miR‑130a‑3p promotes the progression of differentiated thyroid cancer by targeting insulin‑like growth factor 1 Retraction in /10.3892/ol.2023.14017

Guang Yin, Wencheng Kong, Sixin Zheng, Yuqiang Shan, Jian Zhang, Rongchao Ying, Hao Wu
Article Number: 283
Published online on: 12 February 2021

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Article Open Access

miR‑101‑3p sensitizes lung adenocarcinoma cells to irradiation via targeting BIRC5

Xin Meng, Yanfei Sun, Shiying Liu, Yanchao Mu
Article Number: 282
Published online on: 10 February 2021

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Article Open Access

Distinction between benign and malignant soft tissue tumors based on an ultrasonographic evaluation of vascularity and elasticity

Shusa Ohshika, Tatsuro Saruga, Tetsuya Ogawa, Hiroya Ono, Yasuyuki Ishibashi
Article Number: 281
Published online on: 10 February 2021

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Article Open Access

Triptolide inhibits human telomerase reverse transcriptase by downregulating translation factors SP1 and c‑Myc in Epstein‑Barr virus‑positive B lymphocytes

Cong Long, Qiu-Bo Xu, Li Ding, Liu Yang, Wei Ji, Feng Gao, Yong Ji
Article Number: 280
Published online on: 10 February 2021

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Review Open Access

Clinical outcomes and influencing factors of PD‑1/PD‑L1 in hepatocellular carcinoma (Review)

Jiting Wang, Jun Li, Guiju Tang, Yuan Tian, Song Su, Yaling Li
Article Number: 279
Published online on: 10 February 2021

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Article Open Access

AMIGO2 as a novel indicator of liver metastasis in patients with colorectal cancer

Akimitsu Tanio, Hiroaki Saito, Masataka Amisaki, Kazushi Hara, Ken Sugezawa, Chihiro Uejima, Yoichiro Tada, Kyoichi Kihara, Manabu Yamamoto, Kanae Nosaka, Ryo Sasaki, Mitsuhiko Osaki, Futoshi Okada, Yoshiyuki Fujiwara
Article Number: 278
Published online on: 10 February 2021

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Article Open Access

Psoriasin expression is associated with survival in patients with human papillomavirus-positive base of tongue squamous cell carcinoma

Mark Zupancic, Linnea Haeggblom, David Landin, Linda Marklund, Tina Dalianis, Anders Näsman
Article Number: 277
Published online on: 10 February 2021

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Article Open Access

Time density curve of dynamic contrast‑enhanced computed tomography correlates with histological characteristics of pancreatic cancer

Shintaro Goto, Hiroko Seino, Tadashi Yoshizawa, Satoko Morohashi, Keinosuke Ishido, Kenichi Hakamada, Hiroshi Kijima
Article Number: 276
Published online on: 10 February 2021

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Article Open Access

COCH predicts survival and adjuvant TACE response in patients with HCC

Chen Wang, Zhi-Wen Ding, Cheng-Gang Zheng, Siyuan Wang, Zhi-Heng Li, Zi-Mu Zhang, Jian Pan, Jian Wang, Chun Yang
Article Number: 275
Published online on: 10 February 2021

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Inhibition of SUMO2/3 antagonizes isoflurane‑induced cancer‑promoting effect in hepatocellular carcinoma Hep3B cells

Peng Wang, Na Xue, Chunyan Zhang, Shimin Shan, Zhongmin Jiang, Wenhan Wu, Xiaozhi Liu
Article Number: 274
Published online on: 10 February 2021

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Advances in research on the regulatory mechanism of NHE1 in tumors (Review)

Yanxia Hu, Jun Lou, Zhe Jin, Xiaoxu Yang, Weixi Shan, Qian Du, Qiushi Liao, Jingyu Xu, Rui Xie
Article Number: 273
Published online on: 10 February 2021

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MicroRNA‑29a inhibits cell proliferation and arrests cell cycle by modulating p16 methylation in cervical cancer

Anjin Wang, Qiying Xu, Rengaowa Sha, Tonghui Bao, Xiaoli Xi, Guilan Guo
Article Number: 272
Published online on: 09 February 2021

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MicroRNA‑124 suppresses the invasion and proliferation of breast cancer cells by targeting TFAP4

Nier Cha, Baoqing Jia, Yinzai He, Wei Luan, Wenhua Bao, Xiuhua Han, Weishi Gao, Yanwei Gao
Article Number: 271
Published online on: 09 February 2021

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Pancreatic FDG uptake on follow‑up PET/CT in patients with cancer

Hitomi Iwasa, Yoriko Murata, Miki Nishimori, Kana Miyatake, Shino Kohsaki, Naoya Hayashi, Naoki Akagi, Takuhiro Kohsaki, Kazushige Uchida, Takuji Yamagami
Article Number: 270
Published online on: 09 February 2021

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Article

SOX2 enhances cell survival and induces resistance to apoptosis under serum starvation conditions through the AKT/GSK‑3β signaling pathway in esophageal squamous cell carcinoma

Kei Terasaki, Yasuyuki Gen, Naoto Iwai, Tomohiro Soda, Tomoko Kitaichi, Osamu Dohi, Hiroyoshi Taketani, Yuya Seko, Atsushi Umemura, Taichiro Nishikawa, Kanji Yamaguchi, Michihisa Moriguchi, Hideyuki Konishi, Yuji Naito, Yoshito Itoh, Kohichiroh Yasui
Article Number: 269
Published online on: 09 February 2021

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Correction Open Access

[Corrigendum] Isoliquiritigenin induces apoptosis of human bladder cancer T24 cells via a cyclin‑dependent kinase‑independent mechanism

Lingling Si, Xinhui Yang, Xinyan Yan, Yanming Wang, Qiusheng Zheng
Article Number: 268
Published online on: 09 February 2021

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An observational retrospective analysis of the main metastatic site and corresponding locoregional treatment as a prognostic factor in metastatic gastric cancer

Riccardo Giampieri, Luca Cantini, Michela Del Prete, Alessandro Bittoni, Enrica Giglio, Alessandra Mandolesi, Elena Maccaroni, Andrea Lanese, Tania Meletani, Maria Giuditta Baleani, Renato Bisonni, Marina Scarpelli, Rossana Berardi
Article Number: 267
Published online on: 09 February 2021

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Review

Research update on the anticancer effects of buparlisib (Review)

Jinshan Xing, Jun Yang, Yingjiang Gu, Jingyan Yi
Article Number: 266
Published online on: 09 February 2021

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Article Open Access

Inhibiting proliferation and metastasis of osteosarcoma cells by downregulation of long non‑coding RNA colon cancer‑associated transcript 2 targeting microRNA‑143 Retraction in /10.3892/ol.2023.13665

Fengjiang Bi, Can Chen, Jing Fu, Lei Yu, Jia Geng
Article Number: 265
Published online on: 08 February 2021

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Identifying critical protein‑coding genes and long non‑coding RNAs in non‑functioning pituitary adenoma recurrence

Jing Guo, Qiuyue Fang, Yulou Liu, Weiyan Xie, Yazhuo Zhang, Chuzhong Li
Article Number: 264
Published online on: 08 February 2021

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Reduction in the resident intestinal myelomonocytic cell population occurs during ApcMin/+ mouse intestinal tumorigenesis

Olusola O. Faluyi, Mark A. Hull, Alexander F. Markham, Constanze Bonifer, P. Louise Coletta
Article Number: 263
Published online on: 08 February 2021

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Cognitive function of children and adolescent survivors of acute lymphoblastic leukemia: A meta‑analysis

Kalliopi Mavrea, Vasiliki Efthymiou, Katerina Katsibardi, Konstantinos Tsarouhas, Christina Kanaka‑Gantenbein, Demetrios A. Spandidos, George Chrousos, Antonis Kattamis, Flora Bacopoulou
Article Number: 262
Published online on: 05 February 2021

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Expression level of E‑, N‑ and P‑cadherin proteins in endometrial cancer

Łukasz Lewczuk, Anna Pryczynicz, Katarzyna Guzińska‑Ustymowicz
Article Number: 261
Published online on: 04 February 2021

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lncRNA GABPB1 intronic transcript 1 upregulates pigment epithelium‑derived factor via miR‑93 to suppress cell proliferation in hepatocellular carcinoma

Bin Li, Yajun Wei, Qinli Ge, Yucai Duan, Ling Guo
Article Number: 260
Published online on: 04 February 2021

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Squalene epoxidase expression is associated with breast tumor progression and with a poor prognosis in breast cancer

Nah Ihm Kim, Min Ho Park, Sun-Seog Kweon, Namki Cho, Ji Shin Lee
Article Number: 259
Published online on: 04 February 2021

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The emerging role of estrogen related receptorα in complications of non‑small cell lung cancers (Review)

Tapan K. Mukherjee, Parth Malik, John R. Hoidal
Article Number: 258
Published online on: 04 February 2021

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Correction Open Access

[Corrigendum] Decreased expression of ferroportin in prostate cancer

Dong Xue, Cui-Xing Zhou, Yun-Bo Shi, Hao Lu, Xiao-Zhou He
Article Number: 257
Published online on: 04 February 2021

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lncRNA XIST regulates cell proliferation, migration and invasion via regulating miR‑30b and RECK in nasopharyngeal carcinoma

Lingling Sun, Min Zhang, Hongxia Qu
Article Number: 256
Published online on: 04 February 2021

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Long non‑coding RNA TMPO‑AS1 serves as a tumor promoter in pancreatic carcinoma by regulating miR‑383‑5p/SOX11

Feng Xue, Xin Song, Shuai Zhang, Meiwei Niu, Yu Cui, Ye Wang, Ting Zhao
Article Number: 255
Published online on: 04 February 2021

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Interleukin‑1 receptor‑associated kinase 4 as a potential biomarker: Overexpression predicts poor prognosis in patients with glioma

Jialin Wang, Binfeng Liu, Jiawei Yao, Zhendong Liu, Hongbo Wang, Bo Zhang, Xiaoyu Lian, Zhishuai Ren, Liyun Liu, Yanzheng Gao
Article Number: 254
Published online on: 03 February 2021

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Interleukin‑18 and ‑10 may be associated with lymph node metastasis in breast cancer

Teng Ma, Meng Kong
Article Number: 253
Published online on: 03 February 2021

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T cell immune regulator 1 is a prognostic marker associated with immune infiltration in glioblastoma multiforme

Chunxiao Qi, Lei Lei, Jinqu Hu, Gang Wang, Jiyuan Liu, Shaowu Ou
Article Number: 252
Published online on: 03 February 2021

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Dipyridamole induces the phosphorylation of CREB to promote cancer cell proliferation

Lina Abdelghany, Nageh El-Μahdy, Tsuyoshi Kawabata, Shinji Goto, Tao-Sheng Li
Article Number: 251
Published online on: 03 February 2021

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MicroRNA‑429 acts as a tumor suppressor in colorectal cancer by targeting high mobility group box 3

Xiangyang Tian, Jianlan Chang, Ningning Zhang, Shouxin Wu, Huimin Liu, Junyan Yu
Article Number: 250
Published online on: 03 February 2021

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Use of four genes in exosomes as biomarkers for the identification of lung adenocarcinoma and lung squamous cell carcinoma

Bingji Cao, Pengyu Wang, Lina Gu, Junfeng Liu
Article Number: 249
Published online on: 03 February 2021

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MicroRNA‑325‑3p contributes to colorectal carcinoma by targeting cytokeratin 18

Chuanfang Song, Xiujie Wang, Xinxin Zhao, Jiang Ai, Yixuan Qi, Aidong Chen
Article Number: 248
Published online on: 03 February 2021

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Upregulation of microRNA‑181a‑5p increases the sensitivity of HS578T breast cancer cells to cisplatin by inducing vitamin D receptor‑mediated cell autophagy

Jianmin Lin, Xuming Chen, Mingliang Sun, Xiaojiao Qu, Ye Wang, Chenxi Li, Xiujuan Li, Li Zhao, Zhiying Su, Huiming Ye
Article Number: 247
Published online on: 03 February 2021

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Place of hyperthermic intraperitoneal chemotherapy in the armament against pancreatic adenocarcinoma: A survival, mortality and morbidity systematic review

Andreas Larentzakis, Evangelos Anagnostou, Konstantinos Georgiou, Gavriella-Zoi Vrakopoulou, Constantinos G. Zografos, Georgios C. Zografos, Konstantinos G. Toutouzas
Article Number: 246
Published online on: 03 February 2021

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Upregulation of fatty acid synthase in MYC and BCL‑2 double‑expressor lymphoma

Xing Zhong, Zhiliang Liu, Qingfeng Luo, Jingao Li, Weiwei Zhang, Yuerong Shuang
Article Number: 245
Published online on: 02 February 2021

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Retraction Open Access

[Retracted] Inhibition of BAMBI reduces the viability and motility of colon cancer via activating TGF‑β/Smad pathway in vitro and in vivo

Wenzhen Yu, Hong Chai
Article Number: 244
Published online on: 02 February 2021

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Correction Open Access

[Corrigendum] Lactotransferrin expression is downregulated and affects the mitogen‑activated protein kinase pathway in gastric cancer

Gengqiu Luo, Yanhong Zhou, Wei Yi, Hong Yi
Article Number: 243
Published online on: 01 February 2021

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Correction Open Access

[Corrigendum] Telocinobufagin inhibits the epithelial‑to‑mesenchymal transition of breast cancer cells through the PI3K/Akt/Snail signaling pathway

Yuxue Gao, Lihong Shi, Zhen Cao, Xuetao Zhu, Feng Li, Ruyan Wang, Jinyuan Xu, Jinyi Zhong, Baogang Zhang, Shijun Lu
Article Number: 242
Published online on: 31 January 2021

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IL10 hypomethylation is associated with the risk of gastric cancer

Junjian Tang, Ranran Pan, Lele Xu, Qinghua Ma, Xiuru Ying, Jun Zhao, Haibin Zhao, Li Miao, Yue Xu, Shiwei Duan, Jinzhi Wang
Article Number: 241
Published online on: 31 January 2021

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Self‑sampling for high‑risk human papillomavirus as a follow‑up alternative after treatment of high‑grade cervical intraepithelial neoplasia

Ellinor Östensson, Karen Belkić, Torbjörn Ramqvist, Miriam Mints, Sonia Andersson
Article Number: 240
Published online on: 31 January 2021

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Upregulated hsa_circ_0000129 expression promotes proliferation and migration of breast cancer cells

Zhenghua Zhang, Zhan Shi, Su Zhang, Qiong Lu, Haimin Wei, Xueyong Wu, Li Han
Article Number: 239
Published online on: 28 January 2021

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Review Open Access

Mesenchymal stem cell carriers enhance anti‑tumor efficacy of oncolytic virotherapy (Review)

Xianyao Wang, Xing Zhao, Zhixu He
Article Number: 238
Published online on: 28 January 2021

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Article Open Access

Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Article Open Access

Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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