|
1
|
Wen PY and Reardon DA: Neuro-oncology in
2015: Progress in glioma diagnosis, classification and treatment.
Nat Rev Neurol. 12:69–70. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Carlsson SK, Brothers SP and Wahlestedt C:
Emerging treatment strategies for glioblastoma multiforme. EMBO Mol
Med. 6:1359–1370. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zeng Z, Leng T, Feng X, Sun H, Inoue K,
Zhu L and Xiong ZG: Silencing TRPM7 in mouse cortical astrocytes
impairs cell proliferation and migration via ERK and JNK signaling
pathways. PLoS One. 10:e01199122015. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Heigener DF, Gandara DR and Reck M:
Targeting of MEK in lung cancer therapeutics. Lancet Respir Med.
3:319–327. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
5. Liu Z, Dai H, Jia G, Li Y, Liu X and
Ren W: Insufficient radiofrequency ablation promotes human hepatoma
SMMC7721 cell proliferation by stimulating vascular endothelial
growth factor overexpression. Oncol Lett. 9:1893–1896. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Dong F, Tian H, Yan S, Li L, Dong X, Wang
F, Li J, Li C, Cao Z, Liu X, et al: Dihydroartemisinin inhibits
endothelial cell proliferation through the suppression of the ERK
signaling pathway. Int J Mol Med. 35:1381–1387. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Figueira RC, Gomes LR, Neto JS, Silva FC,
Silva ID and Sogayar MC: Correlation between MMPs and their
inhibitors in breast cancer tumor tissue specimens and in cell
lines with different metastatic potential. BMC Cancer. 9:202009.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Bachmeier BE, Nerlich AG, Lichtinghagen R
and Sommerhoff CP: Matrix metalloproteinases (MMPs) in breast
cancer cell lines of different tumorigenicity. Anticancer Res.
21A:3821–3828. 2001.
|
|
9
|
Hotary KB, Yana I, Sabeh F, Li XY,
Holmbeck K, Birkedal-Hansen H, Allen ED, Hiraoka N and Weiss SJ:
Matrix metalloproteinases (MMPs) regulate fibrin-invasive activity
via MT1-MMP-dependent and -independent processes. J Exp Med.
195:295–308. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Forsyth PA, Wong H, Laing TD, Rewcastle
NB, Morris DG, Muzik H, Leco KJ, Johnston RN, Brasher PM,
Sutherland G, et al: Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and
membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in
different aspects of the pathophysiology of malignant gliomas. Br J
Cancer. 79:1828–1835. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Guo XX, An S, Yang Y, Liu Y, Hao Q and Xu
TR: Rap-Interacting Proteins are Key Players in the Rap Symphony
Orchestra. Cell Physiol Biochem. 39:137–156. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Yi L, Zhong X, Chen Z, Wang Q, Yan Y, Wang
J and Deng X: MicroRNA-147b Promotes Proliferation and Invasion of
Human Colorectal Cancer by Targeting RAS Oncogene Family (RAP2B).
Pathobiology. 86:173–181. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhang L, Duan HB and Yang YS: Knockdown of
Rap2B Inhibits the Proliferation and Invasion in Hepatocellular
Carcinoma Cells. Oncol Res. 25:19–27. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Peng YG, Zhang ZQ, Chen YB and Huang JA:
Rap2b promotes proliferation, migration, and invasion of lung
cancer cells. J Recept Signal Transduct Res. 36:459–464. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Raaijmakers JH and Bos JL: Specificity in
Ras and Rap signaling. J Biol Chem. 284:10995–10999. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Itoh M, Nelson CM, Myers CA and Bissell
MJ: Rap1 integrates tissue polarity, lumen formation, and
tumorigenic potential in human breast epithelial cells. Cancer Res.
67:4759–4766. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Kooistra MR, Dubé N and Bos JL: Rap1: A
key regulator in cell-cell junction formation. J Cell Sci.
120:17–22. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Di J, Gao K, Qu D, Yang J and Zheng J:
Rap2B promotes angiogenesis via PI3K/AKT/VEGF signaling pathway in
human renal cell carcinoma. Tumour Biol. 39:10104283177016532017.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Di J, Cao H, Tang J, Lu Z, Gao K, Zhu Z
and Zheng J: Rap2B promotes cell proliferation, migration and
invasion in prostate cancer. Med Oncol. 33:582016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhang X, He Y, Lee KH, Dubois W, Li Z, Wu
X, Kovalchuk A, Zhang W and Huang J: Rap2b, a novel p53 target,
regulates p53-mediated pro-survival function. Cell Cycle.
12:1279–1291. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang M, Zhuang Q and Cui L: miR-194
inhibits cell proliferation and invasion via repression of RAP2B in
bladder cancer. Biomed Pharmacother. 80:268–275. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Miao F, Cui C, Zuo D, Zhang H, Mei P, Chen
H, Wei S, Yang F, Zheng J, Bai J, et al: Rap2B promotes cell
adhesion, proliferation, migration and invasion of human glioma. J
Neurooncol. 143:221–229. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Louis DN, Ohgaki H, Wiestler OD, Cavenee
WK, Burger PC, Jouvet A, Scheithauer BW and Kleihues P: The 2007
WHO classification of tumours of the central nervous system. Acta
Neuropathol. 114:97–109. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Di J, Huang H, Qu D, Tang J, Cao W, Lu Z,
Cheng Q, Yang J, Bai J, Zhang Y, et al: Rap2B promotes
proliferation, migration, and invasion of human breast cancer
through calcium-related ERK1/2 signaling pathway. Sci Rep.
5:123632015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhu L, Sun Y, Zhang S and Wang L: Rap2B
knockdown suppresses malignant progression of hepatocellular
carcinoma by inactivating the PTEN/PI3K/Akt and ERK1/2 pathways.
Mol Cell Biochem. 466:55–63. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Farrell FX, Ohmstede CA, Reep BR and
Lapetina EG: cDNA sequence of a new ras-related gene (rap2b)
isolated from human platelets with sequence homology to rap2.
Nucleic Acids Res. 18:42811990. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Mascaux C, Iannino N, Martin B, Paesmans
M, Berghmans T, Dusart M, Haller A, Lothaire P, Meert AP, Noel S,
et al: The role of RAS oncogene in survival of patients with lung
cancer: A systematic review of the literature with meta-analysis.
Br J Cancer. 92:131–139. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Lv GY, Miao J and Zhang XL: Long Noncoding
RNA XIST Promotes Osteosarcoma Progression by Targeting Ras-Related
Protein RAP2B via miR-320b. Oncol Res. 26:837–846. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zhang Q, Duan L, Xu H, Yuan J, Wu W, Wu Y,
Gao Y and Cheng S: Effects of Rap2b gene on foci formation and
wound-healing of NIH3T3 cells. Wei Sheng Yan Jiu. 39:403–406.
2010.(In Chinese). PubMed/NCBI
|
|
31
|
Zhu Z, Di J, Lu Z, Gao K and Zheng J:
Rap2B GTPase: Structure, functions, and regulation. Tumour Biol.
37:7085–7093. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Xie X, Liu H, Wang M, Ding F, Xiao H, Hu
F, Hu R and Mei J: miR-342-3p targets RAP2B to suppress
proliferation and invasion of non-small cell lung cancer cells.
Tumour Biol. 36:5031–5038. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li Y, Li S and Huang L: Knockdown of
Rap2B, a Ras Superfamily Protein, Inhibits Proliferation,
Migration, and Invasion in Cervical Cancer Cells via Regulating the
ERK1/2 Signaling Pathway. Oncol Res. 26:123–130. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Di JH, Qu DB, Lu Z, Li LT, Cheng Q, Xin Y,
Zhang LZ, Zhang Y and Zheng JN: Rap2B promotes migration and
invasion of human suprarenal epithelioma. Tumour Biol.
35:9387–9394. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Martinelli E, Morgillo F, Troiani T and
Ciardiello F: Cancer resistance to therapies against the
EGFR-RAS-RAF pathway: The role of MEK. Cancer Treat Rev. 53:61–69.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Markovic DS, Vinnakota K, Chirasani S,
Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van
Rooijen N, et al: Gliomas induce and exploit microglial MT1-MMP
expression for tumor expansion. Proc Natl Acad Sci USA.
106:12530–12535. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Mentlein R, Hattermann K and Held-Feindt
J: Lost in disruption: Role of proteases in glioma invasion and
progression. Biochim Biophys Acta. 1825:178–185. 2012.PubMed/NCBI
|
|
38
|
Zheng X, Chopp M, Lu Y, Buller B and Jiang
F: miR-15b and miR-152 reduce glioma cell invasion and angiogenesis
via NRP-2 and MMP-3. Cancer Lett. 329:146–154. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Alaseem A, Alhazzani K, Dondapati P,
Alobid S, Bishayee A and Rathinavelu A: Matrix Metalloproteinases:
A challenging paradigm of cancer management. Semin Cancer Biol.
56:100–115. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Velinov N, Poptodorov G, Gabrovski N and
Gabrovski S: The role of matrixmetalloproteinases in the tumor
growth and metastasis. Khirurgiia (Sofiia). 1:44–49. 2010.(In
Bulgarian).
|
|
41
|
Wang C, Zhao N, Zheng Q, Zhang D and Liu
Y: BHLHE41 promotes U87 and U251 cell proliferation via
ERK/cyclinD1 signaling pathway. Cancer Manag Res. 11:7657–7672.
2019. View Article : Google Scholar : PubMed/NCBI
|
