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Review

Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)

  • Authors:
    • Abdallah Abboud
    • Karim Masrouha
    • Maelle Saliba
    • Rachid Haidar
    • Raya Saab
    • Nabil Khoury
    • Ayman Tawil
    • Said Saghieh
  • View Affiliations / Copyright

    Affiliations: Division of Orthopedic Surgery, Department of Surgery, American University of Beirut Medical Center, Beirut 1013, Lebanon, Division of Orthopedic Oncology, Department of Orthopedic Surgery, NYU Langone Health, New York, NY 10016, USA, Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut 1013, Lebanon, Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut 1013, Lebanon, Department of Diagnostic Radiology, American University of Beirut Medical Center, Beirut 1013, Lebanon
  • Article Number: 354
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    Published online on: March 4, 2021
       https://doi.org/10.3892/ol.2021.12615
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Abstract

Extraskeletal Ewing sarcoma (EES) is a relatively uncommon primary tumor of the soft tissues, which accounts for 20‑30% of all reported cases of ES. Being uncommon, all members of the ES family tumors are treated following the same general protocol of sarcoma tumors. The present review summarizes the diagnosis, management and prognosis of EES, focusing on the differences between the subtypes of ESS. The clinical features and imaging of EES are also discussed. Magnetic resonance imaging is the modality of choice for diagnostic imaging and local staging, while core‑needle biopsy with pathological testing is used to obtain a definitive diagnosis. Although several oncology groups endorse that ES family of tumors should be treated with similar algorithm and protocols, some studies have demonstrated that surgery and radiotherapy may be used as a form of local control. However, further studies are required to conclude the optimum treatment option for EES.
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Copy and paste a formatted citation
Spandidos Publications style
Abboud A, Masrouha K, Saliba M, Haidar R, Saab R, Khoury N, Tawil A and Saghieh S: Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review). Oncol Lett 21: 354, 2021.
APA
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N. ... Saghieh, S. (2021). Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review). Oncology Letters, 21, 354. https://doi.org/10.3892/ol.2021.12615
MLA
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N., Tawil, A., Saghieh, S."Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)". Oncology Letters 21.5 (2021): 354.
Chicago
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N., Tawil, A., Saghieh, S."Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)". Oncology Letters 21, no. 5 (2021): 354. https://doi.org/10.3892/ol.2021.12615
Copy and paste a formatted citation
x
Spandidos Publications style
Abboud A, Masrouha K, Saliba M, Haidar R, Saab R, Khoury N, Tawil A and Saghieh S: Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review). Oncol Lett 21: 354, 2021.
APA
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N. ... Saghieh, S. (2021). Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review). Oncology Letters, 21, 354. https://doi.org/10.3892/ol.2021.12615
MLA
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N., Tawil, A., Saghieh, S."Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)". Oncology Letters 21.5 (2021): 354.
Chicago
Abboud, A., Masrouha, K., Saliba, M., Haidar, R., Saab, R., Khoury, N., Tawil, A., Saghieh, S."Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)". Oncology Letters 21, no. 5 (2021): 354. https://doi.org/10.3892/ol.2021.12615
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