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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2021 Volume 21 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

miR‑20a‑5p inhibits endometrial cancer progression by targeting janus kinase 1

Ying He, Hui Ma, Jing Wang, Yanhua Kang, Qianlong Xue
Article Number: 427
Published online on: 30 March 2021

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Article Open Access

Hydroxyl safflower yellow B combined with doxorubicin inhibits the proliferation of human breast cancer MCF‑7 cells

Kehao Lin, Ze Qin, Chuanjun Qu, Xiaoyu Chen, Qingling Jiang, Minjing Li, Qiusheng Zheng, Defang Li
Article Number: 426
Published online on: 29 March 2021

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Article Open Access

Polysaccharides from sporoderm‑removed spores of Ganoderma lucidum induce apoptosis in human gastric cancer cells via disruption of autophagic flux

Jiayi Zhong, Liu Fang, Rong Chen, Jing Xu, Dandan Guo, Chengjie Guo, Cuiling Guo, Jiajun Chen, Chaojie Chen, Xingya Wang
Article Number: 425
Published online on: 29 March 2021

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Article

Single nucleotide polymorphisms in breast cancer susceptibility gene 1 are associated with susceptibility to lung cancer

Dan Liu, Ya Gao, Lingling Li, He Chen, Lu Bai, Yanli Qu, Baosen Zhou, Ying Yan, Yuxia Zhao
Article Number: 424
Published online on: 29 March 2021

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Article Open Access

Prognostic significance of uPA and uPAR expression in patients with cervical cancer undergoing radiotherapy

Danupon Nantajit, Piyawan Chailapakul, Sarinya Bawornpatarapakorn, Sasikarn Chamchod, Kanyanee Laebua
Article Number: 423
Published online on: 29 March 2021

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Review Open Access

Detection of circulating tumor cells: Advances and critical concerns (Review)

Xiuxiu Hu, Xiaojuan Zang, Yanguan Lv
Article Number: 422
Published online on: 29 March 2021

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Article Open Access

USP18‑deficiency in cervical carcinoma is crucial for the malignant behavior of tumor cells in an ERK signal‑dependent manner

Aonan Pan, Yue Li, Jian Guan, Pengxia Zhang, Chunbin Zhang, Yupeng Han, Tao Zhang, Yao Cheng, Luo Sun, Shizhen Lu, Jinru Weng, Qiaosheng Ren, Shengjie Fan, Weiqun Wang, Jingtao Wang
Article Number: 421
Published online on: 29 March 2021

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Article

The feasibility of circulating tumor DNA analysis as a marker of recurrence in triple-negative breast cancer

Satoshi Okazaki, Takaaki Sasaki, Shunsuke Yasuda, Masahiro Abe, Nana Yoshida, Ryohei Yoshida, Kei Ishibashi, Yoshinori Minami, Shunsuke Okumura, Shinichi Chiba, Hidehiro Takei, Ryusuke Hayashi, Toshihiro Nagato, Hiroya Kobayashi, Ayumu Sugitani, Yusuke Ono, Yusuke Mizukami, Masahiro Kitada, Yoshinobu Ohsaki
Article Number: 420
Published online on: 28 March 2021

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Article Open Access

Upregulation of circRNA_100395 sponges miR‑142‑3p to inhibit gastric cancer progression by targeting the PI3K/AKT axis

Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Xiaojun Zhao
Article Number: 419
Published online on: 28 March 2021

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Article Open Access

Antiaging gene Klotho regulates epithelial‑mesenchymal transition and increases sensitivity to pemetrexed by inducing lipocalin‑2 expression

Kyoshiro Takegahara, Jitsuo Usuda, Tatsuya Inoue, Takumi Sonokawa, Takuma Matsui, Mitsuo Matsumoto
Article Number: 418
Published online on: 28 March 2021

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Review

Improved understanding of gastrointestinal stromal tumors biology as a step for developing new diagnostic and therapeutic schemes (Review)

Marta Magdalena Fudalej, Anna Maria Badowska‑Kozakiewicz
Article Number: 417
Published online on: 28 March 2021

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Article Open Access

circCCDC66 promotes thyroid cancer cell proliferation, migratory and invasive abilities and glycolysis through the miR‑211‑5p/PDK4 axis

Hong Ren, Zhendi Song, Chen Chao, Weizheng Mao
Article Number: 416
Published online on: 26 March 2021

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Correction Open Access

[Corrigendum] Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP‑2 and MMP‑9 expression via the p38MAPK signaling pathway

Shuming Lu, Zhuqing Zhang, Meiru Chen, Chunyan Li, Lina Liu, Yan Li
Article Number: 415
Published online on: 24 March 2021

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Article Open Access

Different role of MSLN and CA125 co-expression as a prognostic predictor between perihilar and distal bile duct carcinoma

Yasuhiro Takihata, Takahiro Einama, Kazuki Kobayashi, Takafumi Suzuki, Naoto Yonamine, Ibuki Fujinuma, Takazumi Tsunenari, Yoji Yamagishi, Toshimitsu Iwasaki, Yoichi Miyata, Eiji Shinto, Sho Ogata, Hironori Tsujimoto, Hideki Ueno, Yoji Kishi
Article Number: 414
Published online on: 23 March 2021

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Review Open Access

Role of cancer‑associated fibroblasts in the resistance to antitumor therapy, and their potential therapeutic mechanisms in non‑small cell lung cancer (Review)

Congcong Chen, Jia Hou, Sizhe Yu, Wenyuan Li, Xiao Wang, Hong Sun, Tianjie Qin, Francois X. Claret, Hui Guo, Zhiyan Liu
Article Number: 413
Published online on: 23 March 2021

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Article Open Access

lncRNA transcription factor 7 is related to deteriorating clinical features and poor prognosis in multiple myeloma, and its knockdown suppresses disease progression by regulating the miR‑203‑mediated Jagged1‑Notch1 signaling pathway

Haiyan Liu, Yaodong Shen, Ya Xu, Li Wang, Chenlu Zhang, Yijing Jiang, Lemin Hong, Hongming Huang, Hong Liu
Article Number: 412
Published online on: 22 March 2021

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Article Open Access

Expression and prognostic value of E2F3 transcription factor in non‑small cell lung cancer

Lei Wu, Shan Wan, Jinfan Li, Yiying Xu, Xiaoli Lou, Maomin Sun, Shouli Wang
Article Number: 411
Published online on: 22 March 2021

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Article Open Access

High expression levels of centromere protein A plus upregulation of the phosphatidylinositol 3‑kinase/Akt/mammalian target of rapamycin signaling pathway affect chemotherapy response and prognosis in patients with breast cancer

Songbo Zhang, Yanyan Xie, Ting Tian, Qianru Yang, Yuting Zhou, Juanjuan Qiu, Li Xu, Nan Wen, Qing Lv, Zhenggui Du
Article Number: 410
Published online on: 22 March 2021

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Article Open Access

Irradiated whole‑cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells

Junying Chen, Yuxiong Ding, Fei Huang, Ruilong Lan, Zeng Wang, Weikang Huang, Ruiqing Chen, Bing Wu, Lengxi Fu, Yunhua Yang, Jun Liu, Jinsheng Hong, Weijian Zhang, Lurong Zhang
Article Number: 409
Published online on: 22 March 2021

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Article Open Access

Dermatopontin as a potential pathogenic factor in endometrial cancer

Haiyun Huang, Zhixiang Hao, Lingyan Long, Zeyuan Yin, Chenyu Wu, Xueyan Zhou, Bei Zhang
Article Number: 408
Published online on: 22 March 2021

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Article Open Access

Transcription factor forkhead box K1 regulates miR‑32 expression and enhances cell proliferation in colorectal cancer

Weiyun Wu, Yongze Chen, Shicai Ye, Hui Yang, Jianyun Yang, Juanhua Quan
Article Number: 407
Published online on: 22 March 2021

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Article Open Access

Construction of in vitro patient‑derived tumor models to evaluate anticancer agents and cancer immunotherapy

Nobuhiko Takahashi, Arisa Higa, Gen Hiyama, Hirosumi Tamura, Hirotaka Hoshi, Yuu Dobashi, Kiyoaki Katahira, Hiroya Ishihara, Kosuke Takagi, Kazuhito Goda, Naoyuki Okabe, Satoshi Muto, Hiroyuki Suzuki, Kenju Shimomura, Shinya Watanabe, Motoki Takagi
Article Number: 406
Published online on: 22 March 2021

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Article Open Access

Diagnostic significance of plasma lipid markers and machine learning‑based algorithm for gastric cancer

Ryo Saito, Kentaro Yoshimura, Katsutoshi Shoda, Shinji Furuya, Hidenori Akaike, Yoshihiko Kawaguchi, Tasuku Murata, Koretsugu Ogata, Tomohiko Iwano, Sen Takeda, Daisuke Ichikawa
Article Number: 405
Published online on: 22 March 2021

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Review Open Access

Regulatory role of long non‑coding RNA UCA1 in signaling pathways and its clinical applications (Review)

Zhaoping Liu, Yanyan Wang, Shunling Yuan, Feng Wen, Jing Liu, Liheng Zou, Ji Zhang
Article Number: 404
Published online on: 19 March 2021

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Article Open Access

Effects of MLL5 and HOXA regulated by NRP1 on radioresistance in A549

Lihong Shao, Yuyu Zhang, Xinkou Gong, Zhuo Dong, Wei Wei, Hongyan Sun, Ran Sun, Lele Cong, Xianling Cong, Shunzi Jin
Article Number: 403
Published online on: 19 March 2021

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Article Open Access

Patients with Helicobacter pylori‑positive gastric cancer with human cytomegalovirus infection have a low tendency of advanced lymphatic metastasis in a Chinese population

Chao Chen, Sian Chen, Zheng Han, Wangkai Xie, Teming Zhang, Chenchen  Mao, Liang Zhang, Xiangwei Sun, Terry Kwok, Xian Shen, Xiangyang Xue
Article Number: 402
Published online on: 19 March 2021

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Article Open Access

Clinical significance of miR‑1298 in cervical cancer and its biological function in vitro Retraction in /10.3892/ol.2024.14283

Haitao Zhang, Ruihong Zhang, Guiling Zhang, Wenjuan Liu, Zhaoyuan Ma, Caiyun Yue, Min Yang
Article Number: 401
Published online on: 18 March 2021

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Article Open Access

Synergistic antitumor effect of the anti‑ErbB2 antibodies trastuzumab and H2‑18 on trastuzumab‑resistant gastric cancer cells

Chao Wang, Lingfei Wang, Beibei Liang, Bo Zhou, Yu Sun, Yanchun Meng, Jian Dong, Lin Chen, Bohua Li
Article Number: 400
Published online on: 18 March 2021

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Article Open Access

SOCS2 is a potential prognostic marker that suppresses the viability of hepatocellular carcinoma cells

Jiankun Liu, Zhiyong Liu, Wei Li, Shurong Zhang
Article Number: 399
Published online on: 18 March 2021

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Review Open Access

Role of FAT1 in health and disease (Review)

Zizhen Peng, Yanyu Gong, Xiaoqiu Liang
Article Number: 398
Published online on: 18 March 2021

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Article Open Access

Novel AXL‑targeted agents overcome FLT3 inhibitor resistance in FLT3‑ITD+ acute myeloid leukemia cells

Yi Liu, Jing Wei, Jiaxin Liu, Weina Ma, Yanting Duan, Daihong Liu
Article Number: 397
Published online on: 18 March 2021

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Article Open Access

MicroRNA‑223‑5p suppresses the progression of nasopharyngeal carcinoma by targeting DCLK1

Zhixuan Zhang, Haifeng Li, Jianqiang You, Haixiang Xue, Xiaoye Tan, Changjiang Chao
Article Number: 396
Published online on: 18 March 2021

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Article

Albendazole exerts antiproliferative effects on prostate cancer cells by inducing reactive oxygen species generation

Ukjin Kim, Changsoo Shin, C-Yoon Kim, Bokyeong Ryu, Jin Kim, Junpil Bang, Jae-Hak Park
Article Number: 395
Published online on: 18 March 2021

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Article Open Access

USP22 promotes melanoma and BRAF inhibitor resistance via YAP stabilization

Ying Wei, Ziyun Jiang, Jianfeng Lu
Article Number: 394
Published online on: 18 March 2021

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Review Open Access

Non‑coding RNAs (miRNAs and lncRNAs) and their roles in lymphogenesis in all types of lymphomas and lymphoid malignancies (Review)

Georgios Drillis, Maria Goulielmaki, Demetrios A. Spandidos, Sofia Aggelaki, Vassilios Zoumpourlis
Article Number: 393
Published online on: 18 March 2021

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Article Open Access

MicroRNA-125a-5p targets LIM kinase 1 to inhibit cisplatin resistance of cervical cancer cells

Yongqian Xu, Yujie Zheng, Yan Duan, Lin Ma, Ping Nan
Article Number: 392
Published online on: 18 March 2021

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Article Open Access

BMPR2 expression level is correlated with low immune infiltration and predicts metastasis and poor survival in osteosarcoma

Hongxin Cao, Shuang Quan, Lu Zhang, Yunzhen Chen, Guangjun Jiao
Article Number: 391
Published online on: 18 March 2021

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Article Open Access

NAMPT promotes hepatitis B virus replication and liver cancer cell proliferation through the regulation of aerobic glycolysis

Hui‑Jie Guo, Hong‑Yu Li, Zi‑Hao Chen, Wen‑Jing Zhou, Jia‑Jie Li, Jia‑Yi  Zhang, Jing Wang, Xing‑Yan Luo, Ting Zeng, Zhao Shi, Chun‑Fen Mo
Article Number: 390
Published online on: 18 March 2021

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Article Open Access

MicroRNA‑365b‑3p represses the proliferation and promotes the apoptosis of non‑small cell lung cancer cells by targeting PPP5C Retraction in /10.3892/ol.2023.14010

Xiaomiao Zhang, Jin Wang, Yuqin Pan, Jun Zhao, Yingge Pan, Yunqi Yan, Zhenya Shen
Article Number: 389
Published online on: 17 March 2021

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Article Open Access

Upregulation of circ‑ASPH contributes to glioma cell proliferation and aggressiveness by targeting the miR‑599/AR/SOCS2‑AS1 signaling pathway

Yi Qu, Li Qi, Liguo Hao, Jian Zhu
Article Number: 388
Published online on: 17 March 2021

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Article Open Access

Knockdown of CLN5 inhibits the tumorigenic properties of glioblastoma cells via the Akt/mTOR signaling pathway

Jiexia Xing, Ying Li, Huilan Zhao
Article Number: 387
Published online on: 17 March 2021

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Article Open Access

MicroRNA‑217 inhibits the proliferation and invasion, and promotes apoptosis of non‑small cell lung cancer cells by targeting sirtuin 1

Guangshun Li, Shouping Zhong
Article Number: 386
Published online on: 17 March 2021

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Article Open Access

Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties

Haruna Makita, Kazuhira Endo, Yoshiya Kasahara, Asuka Nakata, Makiko  Moriyama‑Kita, Kazuya Ishikawa, Takayoshi Ueno, Yosuke Nakanishi, Satoru Kondo, Naohiro Wakisaka, Noriko Gotoh, Tomokazu Yoshizaki
Article Number: 385
Published online on: 16 March 2021

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Review Open Access

Current status of the diagnosis and treatment of gastrointestinal schwannoma (Review)

Zhiyong Qi, Naixv Yang, Mengqi Pi, Wei Yu
Article Number: 384
Published online on: 16 March 2021

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Article Open Access

Macrophage CCL22 expression promotes lymphangiogenesis in patients with tongue squamous cell carcinoma via IL-4/STAT6 in the tumor microenvironment

Satoshi Kimura, Hirotsugu Noguchi, Uki Nanbu, Toshiyuki Nakayama
Article Number: 383
Published online on: 16 March 2021

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Review Open Access

Structure and function of DEAH-box helicase 32 and its role in cancer (Review)

Qingchun Wei, Jinting Geng, Yongquan Chen, Huayue Lin, Jiajia Wang, Zanxi Fang, Fen Wang, Zhongying Zhang
Article Number: 382
Published online on: 16 March 2021

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Article Open Access

Nuclear factor IB is downregulated in vulvar squamous cell carcinoma (VSCC): Unravelling differentially expressed genes in VSCC through gene expression dataset analysis

Shatavisha Dasgupta, Patricia C. Ewing‑Graham, Thierry P.P. Van Den Bosch, Sigrid M.A. Swagemakers, Lindy A.M. Santegoets, Helena C. Van Doorn, Peter J. Van Der Spek, Senada Koljenović, Folkert J. Van Kemenade
Article Number: 381
Published online on: 16 March 2021

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Article Open Access

Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant‑resistant phenotype in breast cancer cells

Margarite D. Matossian, Steven Elliott, Lyndsay V. Rhodes, Elizabeth  C. Martin, Van T. Hoang, Hope E. Burks, William J. Zuercher, David  H. Drewry, Bridgette M. Collins‑Burow, Matthew E. Burow
Article Number: 380
Published online on: 16 March 2021

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Article Open Access

Novel VHL substrate targets SFMBT1 and ZHX2 may be important prognostic predictors in patients with ccRCC

Yufeng Chen, Liangsong Zhu, Song Xue, Jian Shi, Chunfeng He, Qingchuan Zhang
Article Number: 379
Published online on: 16 March 2021

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Review Open Access

Autophagy is a double‑edged sword in the therapy of colorectal cancer (Review)

Bo Zhang, Lantao Liu
Article Number: 378
Published online on: 15 March 2021

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Review Open Access

Role of exosomes in the immune microenvironment of ovarian cancer (Review)

Xiao Li, Yang Liu, Shuangshuang Zheng, Tianyu Zhang, Jing Wu, Yue Sun, Jingzi Zhang, Guoyan Liu
Article Number: 377
Published online on: 15 March 2021

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Review Open Access

Decoding the heterogeneous landscape in the development prostate cancer (Review)

Yenifer Yamile Segura-Moreno, María Carolina Sanabria-Salas, Rodolfo Varela, Jorge Andrés Mesa, Martha Lucia Serrano
Article Number: 376
Published online on: 15 March 2021

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Correction Open Access

[Corrigendum] Dihydroartemisinin inhibits the Raf/ERK/MEK and PI3K/AKT pathways in glioma cells

Wei Du, Changhe Pang, Yake Xue, Qingjun Zhang, Xinting Wei
Article Number: 375
Published online on: 15 March 2021

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Review

Comparative investigation of early‑onset gastric cancer (Review)

Zhen Ma, Xiaolong Liu, Maswikiti Ewetse Paul, Mali  Chen, Peng Zheng, Hao Chen
Article Number: 374
Published online on: 13 March 2021

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Article Open Access

Downregulation of long non‑coding RNA MR4435‑2HG suppresses breast cancer progression via the Wnt/β‑catenin signaling pathway

Deqin Chen, Pengting Tang, Yike Wang, Fang Wan, Jingpei Long, Jun Zhou, Ming Zhuang, Xin Chen
Article Number: 373
Published online on: 13 March 2021

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Article

Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β‑catenin signaling

Jianzhong Yi, Yungeng Liu, Lei Zhang, Chuanfa Fang
Article Number: 372
Published online on: 13 March 2021

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Article Open Access

Long non‑coding RNA LINC00173 enhances cisplatin resistance in hepatocellular carcinoma via the microRNA‑641/RAB14 axis

Guangliang Zhao, Anhua Zhang, Shufang Sun, Yunlong Ding
Article Number: 371
Published online on: 13 March 2021

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Article Open Access

MicroRNA‑27b inhibits the development of melanoma by targeting MYC

Yi Tian, Juanni Zeng, Zongliang Yang
Article Number: 370
Published online on: 12 March 2021

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Review

Altered glycolysis results in drug‑resistant in clinical tumor therapy (Review)

Jinghui Peng, Yangyang Cui, Shipeng Xu, Xiaowei Wu, Yue Huang, Wenbin Zhou, Shui Wang, Ziyi Fu, Hui Xie
Article Number: 369
Published online on: 11 March 2021

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Article Open Access

LINC00052 promotes breast cancer cell progression and metastasis by sponging miR‑145‑5p to modulate TGFBR2 expression

Menglu Dong, Tao Xu, Hanning Li, Xingrui Li
Article Number: 368
Published online on: 11 March 2021

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MicroRNA‑26a inhibits cell proliferation and invasion by targeting FAM98A in breast cancer

Tan Liu, Ziming Wang, Menghao Dong, Jingjing Wei, Yueyin Pan
Article Number: 367
Published online on: 10 March 2021

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Heat maps present the spatial distribution of human papillomavirus infection in Zhejiang Province, China

Jie Xing, Tao Tan, Yang-Long Guo, Jian-Qing Zhu, Ai-Wen Zheng, Ai-Jun Yu, Zheng Niu
Article Number: 366
Published online on: 10 March 2021

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Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non‑small cell lung cancer

Kejie Xie, Xiaoyan Ni, Shanmei Lv, Guozhong Zhou, Honger He
Article Number: 365
Published online on: 10 March 2021

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Article

Effects of ATP-binding cassette transporter G2 in extracellular vesicles on drug resistance of laryngeal cancer cells in in vivo and in vitro

Yan Zhao, Yuetong Chen, Jing Wang, Liang Liu
Article Number: 364
Published online on: 10 March 2021

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Identification of potential oncogenes in triple‑negative breast cancer based on bioinformatics analyses

Xiao Xiao, Zheng Zhang, Ruihan Luo, Rui Peng, Yan Sun, Jia Wang, Xin Chen
Article Number: 363
Published online on: 10 March 2021

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Correction Open Access

[Corrigendum] Construction of the plasmid for expression of EGFP‑M‑IL‑2(88Arg, 125Ala) fusion protein and the anti‑tumor effects exerted by the fusion protein in HeLa-60 cells

Guangcan Shao, Dongmeng Qian, Haitao Wang, Zhiyong Yan, Ming Hu, Tongmei Wang, Bin Wang
Article Number: 362
Published online on: 10 March 2021

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[Corrigendum] Long non‑coding RNA metastasis‑associated lung adenocarcinoma transcript 1 regulates renal cancer cell migration via cofilin‑1

Yali Zhang, Xinyu Guan, Hao Wang, Yong Wang, Dan Yue, Ruibing Chen
Article Number: 361
Published online on: 08 March 2021

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Bioinformatics identification of the candidate microRNAs and construction of a competing endogenous RNA regulatory network in lacrimal gland adenoid cystic carcinoma high‑grade transformation

Meixia Jiang, Xun Liu, Chuanli Zhang, Limin Zhu, Hai-Dong Wu, Lijie Dong, Tingting Wang, Tingting Lin, Yanjin He
Article Number: 360
Published online on: 08 March 2021

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Review Open Access

Research progress of berberine mediated photodynamic therapy (Review)

Ya-Wen An, Hong-Tao Jin, Bo Yuan, Jian-Chun Wang, Cheng Wang, Han-Qing Liu
Article Number: 359
Published online on: 08 March 2021

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Effect of eukaryotic translation initiation factor 4A3 in malignant tumors (Review)

Yuanhang Zhu, Chenchen Ren, Li Yang
Article Number: 358
Published online on: 08 March 2021

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In vivo isolation of circulating tumor cells in patients with different stages of prostate cancer

Gerit Theil, Catrin Boehm, Kersten Fischer, Joanna Bialek, Raschid Hoda, Ekkehard Weber, Sandra Schönburg, Felix Kawan, Paolo Fornara
Article Number: 357
Published online on: 04 March 2021

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Controversial roles of hepatocyte nuclear receptor 4 α on tumorigenesis (Review)

Zhu Wang, Ying Zhang, Jianwen Zhang, Qiong Deng, Hui Liang
Article Number: 356
Published online on: 04 March 2021

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Transcriptome analysis of sinensetin-treated liver cancer cells guided by biological network analysis

Seong Min Kim, Shailima Rampogu, Preethi Vetrivel, Apoorva M. Kulkarni, Sang Eun Ha, Hun Hwan Kim, Keun Woo Lee, Gon Sup Kim
Article Number: 355
Published online on: 04 March 2021

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Review

Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)

Abdallah Abboud, Karim Masrouha, Maelle Saliba, Rachid Haidar, Raya Saab, Nabil Khoury, Ayman Tawil, Said Saghieh
Article Number: 354
Published online on: 04 March 2021

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Potential application of genomic profiling for the diagnosis and treatment of patients with sarcoma

Libin Xu, Xianbiao Xie, Xiaoliang Shi, Peng Zhang, Angen Liu, Jian Wang, Bo Zhang
Article Number: 353
Published online on: 04 March 2021

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Ruxolitinib induces apoptosis of human colorectal cancer cells by downregulating the JAK1/2‑STAT1‑Mcl‑1 axis

Xia Li, Zhe Wang, Shengjie Zhang, Qinghua Yao, Wei Chen, Feiyan Liu
Article Number: 352
Published online on: 04 March 2021

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Article Open Access

A drug targeting 5‑lipoxygenase enhances the activity of a JAK2 inhibitor in CD34+ bone marrow cells from patients with JAK2V617F‑positive polycythemia vera in vitro

Yuan Chen, Hu Zhao, Jing Luo, Youping Liao, Kui Tan, Guoyu Hu
Article Number: 351
Published online on: 04 March 2021

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Retraction Open Access

[Retracted] Effect of integrin receptor‑targeted liposomal paclitaxel for hepatocellular carcinoma targeting and therapy

Liyu Chen, Yanbin Liu, Weiya Wang, Kai Liu
Article Number: 350
Published online on: 03 March 2021

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Protein‑loss of SWI/SNF‑complex core subunits influences prognosis dependent on histological subtypes of intra‑ and extrahepatic cholangiocarcinoma

Britta Janina Wagner, Patrick Sven Plum, Katharina Apel, Marie Scherer, Denise Buchner, Sebastian Brinkmann, Reinhard Buettner, Dirk Stippel, Alexander Quaas, Uta Drebber
Article Number: 349
Published online on: 03 March 2021

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Status of CHEK2 and p53 in patients with early‑onset and conventional gastric cancer

Julita Machlowska, Przemysław Kapusta, Małgorzata Szlendak, Anna Bogdali, Folkert Morsink, Paweł Wołkow, Ryszard Maciejewski, G. Johan A. Offerhaus, Robert Sitarz
Article Number: 348
Published online on: 03 March 2021

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Article

High expression of microRNA‑1266 in hepatocellular carcinoma is associated with poor prognosis of patients and biological cell growth

Xinhui Huang, Yongping Lai, Na Yao, Yongliang Cui, Xiaoling Yu, Zhixiong Cai, Yupeng Tang, Yao Huang, Jinhua Zeng
Article Number: 347
Published online on: 03 March 2021

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Targeting of FK506 binding protein 5 by miR‑203 affects the progression of breast cancer via regulating the fatty acid degradation pathway and potential drug‑repurposing

Dan Yang, Yaqin Fan, Beibei Xie, Jie Yang
Article Number: 346
Published online on: 03 March 2021

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Long non‑coding RNA maternally expressed gene 3 affects cell proliferation, apoptosis and migration by targeting the microRNA‑9‑5p/midkine axis and activating the phosphoinositide‑dependent kinase/AKT pathway in hepatocellular carcinoma

Dezhi Wu, Zheng Ma, Deyu Ma, Qiquan Li
Article Number: 345
Published online on: 03 March 2021

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Preclinical analysis of novel prognostic transcription factors and immune‑related gene signatures for bladder cancer via TCGA‑based bioinformatic analysis

Yuyou Deng, Xin Hong, Chengfan Yu, Hui Li, Qiang Wang, Yi Zhang, Tian Wang, Xiaofeng Wang
Article Number: 344
Published online on: 03 March 2021

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Review

Pathways and role of MALAT1 in esophageal and gastric cancer (Review)

Athanasios Syllaios, Dimitrios Moris, Georgia Sofia Karachaliou, Stratigoula Sakellariou, Ioannis Karavokyros, Maria Gazouli, Dimitrios Schizas
Article Number: 343
Published online on: 02 March 2021

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EZH2 and SMYD3 expression in papillary thyroid cancer

Nadia Sawicka‑Gutaj, Sara Shawkat, Mirosław Andrusiewicz, Paulina Ziółkowska, Agata Czarnywojtek, Paweł Gut, Marek Ruchała
Article Number: 342
Published online on: 02 March 2021

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Case Report

Occurrence of quadruple squamous cell carcinoma following allogeneic hematopoietic stem cell transplantation for leukemia: A case report

Chunhong Hu, Xue Wang, Yue Pan, Long Shu, Fang Wu
Article Number: 341
Published online on: 02 March 2021

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Decitabine inhibits the proliferation of human T‑cell acute lymphoblastic leukemia molt4 cells and promotes apoptosis partly by regulating the PI3K/AKT/mTOR pathway

Gang Zhang, Xiaohui Gao, Xiaoyan Zhao, Haibing Wu, Minchao Yan, Yuan Li, Hui Zeng, Zhaoning Ji, Xiaojun Guo
Article Number: 340
Published online on: 02 March 2021

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May-2026 Volume 31 Issue 5

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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