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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2021 Volume 21 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

miR‑20a‑5p inhibits endometrial cancer progression by targeting janus kinase 1

Ying He, Hui Ma, Jing Wang, Yanhua Kang, Qianlong Xue
Article Number: 427
Published online on: 30 March 2021

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Article Open Access

Hydroxyl safflower yellow B combined with doxorubicin inhibits the proliferation of human breast cancer MCF‑7 cells

Kehao Lin, Ze Qin, Chuanjun Qu, Xiaoyu Chen, Qingling Jiang, Minjing Li, Qiusheng Zheng, Defang Li
Article Number: 426
Published online on: 29 March 2021

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Article Open Access

Polysaccharides from sporoderm‑removed spores of Ganoderma lucidum induce apoptosis in human gastric cancer cells via disruption of autophagic flux

Jiayi Zhong, Liu Fang, Rong Chen, Jing Xu, Dandan Guo, Chengjie Guo, Cuiling Guo, Jiajun Chen, Chaojie Chen, Xingya Wang
Article Number: 425
Published online on: 29 March 2021

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Article

Single nucleotide polymorphisms in breast cancer susceptibility gene 1 are associated with susceptibility to lung cancer

Dan Liu, Ya Gao, Lingling Li, He Chen, Lu Bai, Yanli Qu, Baosen Zhou, Ying Yan, Yuxia Zhao
Article Number: 424
Published online on: 29 March 2021

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Article Open Access

Prognostic significance of uPA and uPAR expression in patients with cervical cancer undergoing radiotherapy

Danupon Nantajit, Piyawan Chailapakul, Sarinya Bawornpatarapakorn, Sasikarn Chamchod, Kanyanee Laebua
Article Number: 423
Published online on: 29 March 2021

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Review Open Access

Detection of circulating tumor cells: Advances and critical concerns (Review)

Xiuxiu Hu, Xiaojuan Zang, Yanguan Lv
Article Number: 422
Published online on: 29 March 2021

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Article Open Access

USP18‑deficiency in cervical carcinoma is crucial for the malignant behavior of tumor cells in an ERK signal‑dependent manner

Aonan Pan, Yue Li, Jian Guan, Pengxia Zhang, Chunbin Zhang, Yupeng Han, Tao Zhang, Yao Cheng, Luo Sun, Shizhen Lu, Jinru Weng, Qiaosheng Ren, Shengjie Fan, Weiqun Wang, Jingtao Wang
Article Number: 421
Published online on: 29 March 2021

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Article

The feasibility of circulating tumor DNA analysis as a marker of recurrence in triple-negative breast cancer

Satoshi Okazaki, Takaaki Sasaki, Shunsuke Yasuda, Masahiro Abe, Nana Yoshida, Ryohei Yoshida, Kei Ishibashi, Yoshinori Minami, Shunsuke Okumura, Shinichi Chiba, Hidehiro Takei, Ryusuke Hayashi, Toshihiro Nagato, Hiroya Kobayashi, Ayumu Sugitani, Yusuke Ono, Yusuke Mizukami, Masahiro Kitada, Yoshinobu Ohsaki
Article Number: 420
Published online on: 28 March 2021

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Article Open Access

Upregulation of circRNA_100395 sponges miR‑142‑3p to inhibit gastric cancer progression by targeting the PI3K/AKT axis

Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Xiaojun Zhao
Article Number: 419
Published online on: 28 March 2021

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Article Open Access

Antiaging gene Klotho regulates epithelial‑mesenchymal transition and increases sensitivity to pemetrexed by inducing lipocalin‑2 expression

Kyoshiro Takegahara, Jitsuo Usuda, Tatsuya Inoue, Takumi Sonokawa, Takuma Matsui, Mitsuo Matsumoto
Article Number: 418
Published online on: 28 March 2021

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Review

Improved understanding of gastrointestinal stromal tumors biology as a step for developing new diagnostic and therapeutic schemes (Review)

Marta Magdalena Fudalej, Anna Maria Badowska‑Kozakiewicz
Article Number: 417
Published online on: 28 March 2021

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Article Open Access

circCCDC66 promotes thyroid cancer cell proliferation, migratory and invasive abilities and glycolysis through the miR‑211‑5p/PDK4 axis

Hong Ren, Zhendi Song, Chen Chao, Weizheng Mao
Article Number: 416
Published online on: 26 March 2021

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Correction Open Access

[Corrigendum] Silibinin inhibits the migration and invasion of human gastric cancer SGC7901 cells by downregulating MMP‑2 and MMP‑9 expression via the p38MAPK signaling pathway

Shuming Lu, Zhuqing Zhang, Meiru Chen, Chunyan Li, Lina Liu, Yan Li
Article Number: 415
Published online on: 24 March 2021

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Article Open Access

Different role of MSLN and CA125 co-expression as a prognostic predictor between perihilar and distal bile duct carcinoma

Yasuhiro Takihata, Takahiro Einama, Kazuki Kobayashi, Takafumi Suzuki, Naoto Yonamine, Ibuki Fujinuma, Takazumi Tsunenari, Yoji Yamagishi, Toshimitsu Iwasaki, Yoichi Miyata, Eiji Shinto, Sho Ogata, Hironori Tsujimoto, Hideki Ueno, Yoji Kishi
Article Number: 414
Published online on: 23 March 2021

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Review Open Access

Role of cancer‑associated fibroblasts in the resistance to antitumor therapy, and their potential therapeutic mechanisms in non‑small cell lung cancer (Review)

Congcong Chen, Jia Hou, Sizhe Yu, Wenyuan Li, Xiao Wang, Hong Sun, Tianjie Qin, Francois X. Claret, Hui Guo, Zhiyan Liu
Article Number: 413
Published online on: 23 March 2021

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Article Open Access

lncRNA transcription factor 7 is related to deteriorating clinical features and poor prognosis in multiple myeloma, and its knockdown suppresses disease progression by regulating the miR‑203‑mediated Jagged1‑Notch1 signaling pathway

Haiyan Liu, Yaodong Shen, Ya Xu, Li Wang, Chenlu Zhang, Yijing Jiang, Lemin Hong, Hongming Huang, Hong Liu
Article Number: 412
Published online on: 22 March 2021

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Article Open Access

Expression and prognostic value of E2F3 transcription factor in non‑small cell lung cancer

Lei Wu, Shan Wan, Jinfan Li, Yiying Xu, Xiaoli Lou, Maomin Sun, Shouli Wang
Article Number: 411
Published online on: 22 March 2021

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Article Open Access

High expression levels of centromere protein A plus upregulation of the phosphatidylinositol 3‑kinase/Akt/mammalian target of rapamycin signaling pathway affect chemotherapy response and prognosis in patients with breast cancer

Songbo Zhang, Yanyan Xie, Ting Tian, Qianru Yang, Yuting Zhou, Juanjuan Qiu, Li Xu, Nan Wen, Qing Lv, Zhenggui Du
Article Number: 410
Published online on: 22 March 2021

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Article Open Access

Irradiated whole‑cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells

Junying Chen, Yuxiong Ding, Fei Huang, Ruilong Lan, Zeng Wang, Weikang Huang, Ruiqing Chen, Bing Wu, Lengxi Fu, Yunhua Yang, Jun Liu, Jinsheng Hong, Weijian Zhang, Lurong Zhang
Article Number: 409
Published online on: 22 March 2021

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Article Open Access

Dermatopontin as a potential pathogenic factor in endometrial cancer

Haiyun Huang, Zhixiang Hao, Lingyan Long, Zeyuan Yin, Chenyu Wu, Xueyan Zhou, Bei Zhang
Article Number: 408
Published online on: 22 March 2021

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Article Open Access

Transcription factor forkhead box K1 regulates miR‑32 expression and enhances cell proliferation in colorectal cancer

Weiyun Wu, Yongze Chen, Shicai Ye, Hui Yang, Jianyun Yang, Juanhua Quan
Article Number: 407
Published online on: 22 March 2021

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Article Open Access

Construction of in vitro patient‑derived tumor models to evaluate anticancer agents and cancer immunotherapy

Nobuhiko Takahashi, Arisa Higa, Gen Hiyama, Hirosumi Tamura, Hirotaka Hoshi, Yuu Dobashi, Kiyoaki Katahira, Hiroya Ishihara, Kosuke Takagi, Kazuhito Goda, Naoyuki Okabe, Satoshi Muto, Hiroyuki Suzuki, Kenju Shimomura, Shinya Watanabe, Motoki Takagi
Article Number: 406
Published online on: 22 March 2021

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Article Open Access

Diagnostic significance of plasma lipid markers and machine learning‑based algorithm for gastric cancer

Ryo Saito, Kentaro Yoshimura, Katsutoshi Shoda, Shinji Furuya, Hidenori Akaike, Yoshihiko Kawaguchi, Tasuku Murata, Koretsugu Ogata, Tomohiko Iwano, Sen Takeda, Daisuke Ichikawa
Article Number: 405
Published online on: 22 March 2021

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Review Open Access

Regulatory role of long non‑coding RNA UCA1 in signaling pathways and its clinical applications (Review)

Zhaoping Liu, Yanyan Wang, Shunling Yuan, Feng Wen, Jing Liu, Liheng Zou, Ji Zhang
Article Number: 404
Published online on: 19 March 2021

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Article Open Access

Effects of MLL5 and HOXA regulated by NRP1 on radioresistance in A549

Lihong Shao, Yuyu Zhang, Xinkou Gong, Zhuo Dong, Wei Wei, Hongyan Sun, Ran Sun, Lele Cong, Xianling Cong, Shunzi Jin
Article Number: 403
Published online on: 19 March 2021

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Article Open Access

Patients with Helicobacter pylori‑positive gastric cancer with human cytomegalovirus infection have a low tendency of advanced lymphatic metastasis in a Chinese population

Chao Chen, Sian Chen, Zheng Han, Wangkai Xie, Teming Zhang, Chenchen  Mao, Liang Zhang, Xiangwei Sun, Terry Kwok, Xian Shen, Xiangyang Xue
Article Number: 402
Published online on: 19 March 2021

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Article Open Access

Clinical significance of miR‑1298 in cervical cancer and its biological function in vitro Retraction in /10.3892/ol.2024.14283

Haitao Zhang, Ruihong Zhang, Guiling Zhang, Wenjuan Liu, Zhaoyuan Ma, Caiyun Yue, Min Yang
Article Number: 401
Published online on: 18 March 2021

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Article Open Access

Synergistic antitumor effect of the anti‑ErbB2 antibodies trastuzumab and H2‑18 on trastuzumab‑resistant gastric cancer cells

Chao Wang, Lingfei Wang, Beibei Liang, Bo Zhou, Yu Sun, Yanchun Meng, Jian Dong, Lin Chen, Bohua Li
Article Number: 400
Published online on: 18 March 2021

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Article Open Access

SOCS2 is a potential prognostic marker that suppresses the viability of hepatocellular carcinoma cells

Jiankun Liu, Zhiyong Liu, Wei Li, Shurong Zhang
Article Number: 399
Published online on: 18 March 2021

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Review Open Access

Role of FAT1 in health and disease (Review)

Zizhen Peng, Yanyu Gong, Xiaoqiu Liang
Article Number: 398
Published online on: 18 March 2021

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Article Open Access

Novel AXL‑targeted agents overcome FLT3 inhibitor resistance in FLT3‑ITD+ acute myeloid leukemia cells

Yi Liu, Jing Wei, Jiaxin Liu, Weina Ma, Yanting Duan, Daihong Liu
Article Number: 397
Published online on: 18 March 2021

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Article Open Access

MicroRNA‑223‑5p suppresses the progression of nasopharyngeal carcinoma by targeting DCLK1

Zhixuan Zhang, Haifeng Li, Jianqiang You, Haixiang Xue, Xiaoye Tan, Changjiang Chao
Article Number: 396
Published online on: 18 March 2021

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Article

Albendazole exerts antiproliferative effects on prostate cancer cells by inducing reactive oxygen species generation

Ukjin Kim, Changsoo Shin, C-Yoon Kim, Bokyeong Ryu, Jin Kim, Junpil Bang, Jae-Hak Park
Article Number: 395
Published online on: 18 March 2021

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Article Open Access

USP22 promotes melanoma and BRAF inhibitor resistance via YAP stabilization

Ying Wei, Ziyun Jiang, Jianfeng Lu
Article Number: 394
Published online on: 18 March 2021

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Review Open Access

Non‑coding RNAs (miRNAs and lncRNAs) and their roles in lymphogenesis in all types of lymphomas and lymphoid malignancies (Review)

Georgios Drillis, Maria Goulielmaki, Demetrios A. Spandidos, Sofia Aggelaki, Vassilios Zoumpourlis
Article Number: 393
Published online on: 18 March 2021

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Article Open Access

MicroRNA-125a-5p targets LIM kinase 1 to inhibit cisplatin resistance of cervical cancer cells

Yongqian Xu, Yujie Zheng, Yan Duan, Lin Ma, Ping Nan
Article Number: 392
Published online on: 18 March 2021

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Article Open Access

BMPR2 expression level is correlated with low immune infiltration and predicts metastasis and poor survival in osteosarcoma

Hongxin Cao, Shuang Quan, Lu Zhang, Yunzhen Chen, Guangjun Jiao
Article Number: 391
Published online on: 18 March 2021

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Article Open Access

NAMPT promotes hepatitis B virus replication and liver cancer cell proliferation through the regulation of aerobic glycolysis

Hui‑Jie Guo, Hong‑Yu Li, Zi‑Hao Chen, Wen‑Jing Zhou, Jia‑Jie Li, Jia‑Yi  Zhang, Jing Wang, Xing‑Yan Luo, Ting Zeng, Zhao Shi, Chun‑Fen Mo
Article Number: 390
Published online on: 18 March 2021

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Article Open Access

MicroRNA‑365b‑3p represses the proliferation and promotes the apoptosis of non‑small cell lung cancer cells by targeting PPP5C Retraction in /10.3892/ol.2023.14010

Xiaomiao Zhang, Jin Wang, Yuqin Pan, Jun Zhao, Yingge Pan, Yunqi Yan, Zhenya Shen
Article Number: 389
Published online on: 17 March 2021

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Article Open Access

Upregulation of circ‑ASPH contributes to glioma cell proliferation and aggressiveness by targeting the miR‑599/AR/SOCS2‑AS1 signaling pathway

Yi Qu, Li Qi, Liguo Hao, Jian Zhu
Article Number: 388
Published online on: 17 March 2021

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Article Open Access

Knockdown of CLN5 inhibits the tumorigenic properties of glioblastoma cells via the Akt/mTOR signaling pathway

Jiexia Xing, Ying Li, Huilan Zhao
Article Number: 387
Published online on: 17 March 2021

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Article Open Access

MicroRNA‑217 inhibits the proliferation and invasion, and promotes apoptosis of non‑small cell lung cancer cells by targeting sirtuin 1

Guangshun Li, Shouping Zhong
Article Number: 386
Published online on: 17 March 2021

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Article Open Access

Xenografts derived from patients with head and neck cancer recapitulate patient tumour properties

Haruna Makita, Kazuhira Endo, Yoshiya Kasahara, Asuka Nakata, Makiko  Moriyama‑Kita, Kazuya Ishikawa, Takayoshi Ueno, Yosuke Nakanishi, Satoru Kondo, Naohiro Wakisaka, Noriko Gotoh, Tomokazu Yoshizaki
Article Number: 385
Published online on: 16 March 2021

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Review Open Access

Current status of the diagnosis and treatment of gastrointestinal schwannoma (Review)

Zhiyong Qi, Naixv Yang, Mengqi Pi, Wei Yu
Article Number: 384
Published online on: 16 March 2021

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Article Open Access

Macrophage CCL22 expression promotes lymphangiogenesis in patients with tongue squamous cell carcinoma via IL-4/STAT6 in the tumor microenvironment

Satoshi Kimura, Hirotsugu Noguchi, Uki Nanbu, Toshiyuki Nakayama
Article Number: 383
Published online on: 16 March 2021

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Review Open Access

Structure and function of DEAH-box helicase 32 and its role in cancer (Review)

Qingchun Wei, Jinting Geng, Yongquan Chen, Huayue Lin, Jiajia Wang, Zanxi Fang, Fen Wang, Zhongying Zhang
Article Number: 382
Published online on: 16 March 2021

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Article Open Access

Nuclear factor IB is downregulated in vulvar squamous cell carcinoma (VSCC): Unravelling differentially expressed genes in VSCC through gene expression dataset analysis

Shatavisha Dasgupta, Patricia C. Ewing‑Graham, Thierry P.P. Van Den Bosch, Sigrid M.A. Swagemakers, Lindy A.M. Santegoets, Helena C. Van Doorn, Peter J. Van Der Spek, Senada Koljenović, Folkert J. Van Kemenade
Article Number: 381
Published online on: 16 March 2021

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Article Open Access

Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant‑resistant phenotype in breast cancer cells

Margarite D. Matossian, Steven Elliott, Lyndsay V. Rhodes, Elizabeth  C. Martin, Van T. Hoang, Hope E. Burks, William J. Zuercher, David  H. Drewry, Bridgette M. Collins‑Burow, Matthew E. Burow
Article Number: 380
Published online on: 16 March 2021

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Article Open Access

Novel VHL substrate targets SFMBT1 and ZHX2 may be important prognostic predictors in patients with ccRCC

Yufeng Chen, Liangsong Zhu, Song Xue, Jian Shi, Chunfeng He, Qingchuan Zhang
Article Number: 379
Published online on: 16 March 2021

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Review Open Access

Autophagy is a double‑edged sword in the therapy of colorectal cancer (Review)

Bo Zhang, Lantao Liu
Article Number: 378
Published online on: 15 March 2021

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Review Open Access

Role of exosomes in the immune microenvironment of ovarian cancer (Review)

Xiao Li, Yang Liu, Shuangshuang Zheng, Tianyu Zhang, Jing Wu, Yue Sun, Jingzi Zhang, Guoyan Liu
Article Number: 377
Published online on: 15 March 2021

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Review Open Access

Decoding the heterogeneous landscape in the development prostate cancer (Review)

Yenifer Yamile Segura-Moreno, María Carolina Sanabria-Salas, Rodolfo Varela, Jorge Andrés Mesa, Martha Lucia Serrano
Article Number: 376
Published online on: 15 March 2021

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Correction Open Access

[Corrigendum] Dihydroartemisinin inhibits the Raf/ERK/MEK and PI3K/AKT pathways in glioma cells

Wei Du, Changhe Pang, Yake Xue, Qingjun Zhang, Xinting Wei
Article Number: 375
Published online on: 15 March 2021

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Review

Comparative investigation of early‑onset gastric cancer (Review)

Zhen Ma, Xiaolong Liu, Maswikiti Ewetse Paul, Mali  Chen, Peng Zheng, Hao Chen
Article Number: 374
Published online on: 13 March 2021

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Article Open Access

Downregulation of long non‑coding RNA MR4435‑2HG suppresses breast cancer progression via the Wnt/β‑catenin signaling pathway

Deqin Chen, Pengting Tang, Yike Wang, Fang Wan, Jingpei Long, Jun Zhou, Ming Zhuang, Xin Chen
Article Number: 373
Published online on: 13 March 2021

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Article

Secreted phosphoprotein-1 accelerates the progression of human colorectal cancer through activating β‑catenin signaling

Jianzhong Yi, Yungeng Liu, Lei Zhang, Chuanfa Fang
Article Number: 372
Published online on: 13 March 2021

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Article Open Access

Long non‑coding RNA LINC00173 enhances cisplatin resistance in hepatocellular carcinoma via the microRNA‑641/RAB14 axis

Guangliang Zhao, Anhua Zhang, Shufang Sun, Yunlong Ding
Article Number: 371
Published online on: 13 March 2021

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Article Open Access

MicroRNA‑27b inhibits the development of melanoma by targeting MYC

Yi Tian, Juanni Zeng, Zongliang Yang
Article Number: 370
Published online on: 12 March 2021

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Review

Altered glycolysis results in drug‑resistant in clinical tumor therapy (Review)

Jinghui Peng, Yangyang Cui, Shipeng Xu, Xiaowei Wu, Yue Huang, Wenbin Zhou, Shui Wang, Ziyi Fu, Hui Xie
Article Number: 369
Published online on: 11 March 2021

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Article Open Access

LINC00052 promotes breast cancer cell progression and metastasis by sponging miR‑145‑5p to modulate TGFBR2 expression

Menglu Dong, Tao Xu, Hanning Li, Xingrui Li
Article Number: 368
Published online on: 11 March 2021

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MicroRNA‑26a inhibits cell proliferation and invasion by targeting FAM98A in breast cancer

Tan Liu, Ziming Wang, Menghao Dong, Jingjing Wei, Yueyin Pan
Article Number: 367
Published online on: 10 March 2021

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Heat maps present the spatial distribution of human papillomavirus infection in Zhejiang Province, China

Jie Xing, Tao Tan, Yang-Long Guo, Jian-Qing Zhu, Ai-Wen Zheng, Ai-Jun Yu, Zheng Niu
Article Number: 366
Published online on: 10 March 2021

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Synergistic effects of olaparib combined with ERCC1 on the sensitivity of cisplatin in non‑small cell lung cancer

Kejie Xie, Xiaoyan Ni, Shanmei Lv, Guozhong Zhou, Honger He
Article Number: 365
Published online on: 10 March 2021

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Article

Effects of ATP-binding cassette transporter G2 in extracellular vesicles on drug resistance of laryngeal cancer cells in in vivo and in vitro

Yan Zhao, Yuetong Chen, Jing Wang, Liang Liu
Article Number: 364
Published online on: 10 March 2021

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Identification of potential oncogenes in triple‑negative breast cancer based on bioinformatics analyses

Xiao Xiao, Zheng Zhang, Ruihan Luo, Rui Peng, Yan Sun, Jia Wang, Xin Chen
Article Number: 363
Published online on: 10 March 2021

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Correction Open Access

[Corrigendum] Construction of the plasmid for expression of EGFP‑M‑IL‑2(88Arg, 125Ala) fusion protein and the anti‑tumor effects exerted by the fusion protein in HeLa-60 cells

Guangcan Shao, Dongmeng Qian, Haitao Wang, Zhiyong Yan, Ming Hu, Tongmei Wang, Bin Wang
Article Number: 362
Published online on: 10 March 2021

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[Corrigendum] Long non‑coding RNA metastasis‑associated lung adenocarcinoma transcript 1 regulates renal cancer cell migration via cofilin‑1

Yali Zhang, Xinyu Guan, Hao Wang, Yong Wang, Dan Yue, Ruibing Chen
Article Number: 361
Published online on: 08 March 2021

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Bioinformatics identification of the candidate microRNAs and construction of a competing endogenous RNA regulatory network in lacrimal gland adenoid cystic carcinoma high‑grade transformation

Meixia Jiang, Xun Liu, Chuanli Zhang, Limin Zhu, Hai-Dong Wu, Lijie Dong, Tingting Wang, Tingting Lin, Yanjin He
Article Number: 360
Published online on: 08 March 2021

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Review Open Access

Research progress of berberine mediated photodynamic therapy (Review)

Ya-Wen An, Hong-Tao Jin, Bo Yuan, Jian-Chun Wang, Cheng Wang, Han-Qing Liu
Article Number: 359
Published online on: 08 March 2021

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Effect of eukaryotic translation initiation factor 4A3 in malignant tumors (Review)

Yuanhang Zhu, Chenchen Ren, Li Yang
Article Number: 358
Published online on: 08 March 2021

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Article Open Access

In vivo isolation of circulating tumor cells in patients with different stages of prostate cancer

Gerit Theil, Catrin Boehm, Kersten Fischer, Joanna Bialek, Raschid Hoda, Ekkehard Weber, Sandra Schönburg, Felix Kawan, Paolo Fornara
Article Number: 357
Published online on: 04 March 2021

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Review Open Access

Controversial roles of hepatocyte nuclear receptor 4 α on tumorigenesis (Review)

Zhu Wang, Ying Zhang, Jianwen Zhang, Qiong Deng, Hui Liang
Article Number: 356
Published online on: 04 March 2021

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Article Open Access

Transcriptome analysis of sinensetin-treated liver cancer cells guided by biological network analysis

Seong Min Kim, Shailima Rampogu, Preethi Vetrivel, Apoorva M. Kulkarni, Sang Eun Ha, Hun Hwan Kim, Keun Woo Lee, Gon Sup Kim
Article Number: 355
Published online on: 04 March 2021

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Review

Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis (Review)

Abdallah Abboud, Karim Masrouha, Maelle Saliba, Rachid Haidar, Raya Saab, Nabil Khoury, Ayman Tawil, Said Saghieh
Article Number: 354
Published online on: 04 March 2021

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Article Open Access

Potential application of genomic profiling for the diagnosis and treatment of patients with sarcoma

Libin Xu, Xianbiao Xie, Xiaoliang Shi, Peng Zhang, Angen Liu, Jian Wang, Bo Zhang
Article Number: 353
Published online on: 04 March 2021

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Article Open Access

Ruxolitinib induces apoptosis of human colorectal cancer cells by downregulating the JAK1/2‑STAT1‑Mcl‑1 axis

Xia Li, Zhe Wang, Shengjie Zhang, Qinghua Yao, Wei Chen, Feiyan Liu
Article Number: 352
Published online on: 04 March 2021

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Article Open Access

A drug targeting 5‑lipoxygenase enhances the activity of a JAK2 inhibitor in CD34+ bone marrow cells from patients with JAK2V617F‑positive polycythemia vera in vitro

Yuan Chen, Hu Zhao, Jing Luo, Youping Liao, Kui Tan, Guoyu Hu
Article Number: 351
Published online on: 04 March 2021

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Retraction Open Access

[Retracted] Effect of integrin receptor‑targeted liposomal paclitaxel for hepatocellular carcinoma targeting and therapy

Liyu Chen, Yanbin Liu, Weiya Wang, Kai Liu
Article Number: 350
Published online on: 03 March 2021

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Article Open Access

Protein‑loss of SWI/SNF‑complex core subunits influences prognosis dependent on histological subtypes of intra‑ and extrahepatic cholangiocarcinoma

Britta Janina Wagner, Patrick Sven Plum, Katharina Apel, Marie Scherer, Denise Buchner, Sebastian Brinkmann, Reinhard Buettner, Dirk Stippel, Alexander Quaas, Uta Drebber
Article Number: 349
Published online on: 03 March 2021

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Status of CHEK2 and p53 in patients with early‑onset and conventional gastric cancer

Julita Machlowska, Przemysław Kapusta, Małgorzata Szlendak, Anna Bogdali, Folkert Morsink, Paweł Wołkow, Ryszard Maciejewski, G. Johan A. Offerhaus, Robert Sitarz
Article Number: 348
Published online on: 03 March 2021

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Article

High expression of microRNA‑1266 in hepatocellular carcinoma is associated with poor prognosis of patients and biological cell growth

Xinhui Huang, Yongping Lai, Na Yao, Yongliang Cui, Xiaoling Yu, Zhixiong Cai, Yupeng Tang, Yao Huang, Jinhua Zeng
Article Number: 347
Published online on: 03 March 2021

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Article Open Access

Targeting of FK506 binding protein 5 by miR‑203 affects the progression of breast cancer via regulating the fatty acid degradation pathway and potential drug‑repurposing

Dan Yang, Yaqin Fan, Beibei Xie, Jie Yang
Article Number: 346
Published online on: 03 March 2021

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Article Open Access

Long non‑coding RNA maternally expressed gene 3 affects cell proliferation, apoptosis and migration by targeting the microRNA‑9‑5p/midkine axis and activating the phosphoinositide‑dependent kinase/AKT pathway in hepatocellular carcinoma

Dezhi Wu, Zheng Ma, Deyu Ma, Qiquan Li
Article Number: 345
Published online on: 03 March 2021

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Preclinical analysis of novel prognostic transcription factors and immune‑related gene signatures for bladder cancer via TCGA‑based bioinformatic analysis

Yuyou Deng, Xin Hong, Chengfan Yu, Hui Li, Qiang Wang, Yi Zhang, Tian Wang, Xiaofeng Wang
Article Number: 344
Published online on: 03 March 2021

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Review

Pathways and role of MALAT1 in esophageal and gastric cancer (Review)

Athanasios Syllaios, Dimitrios Moris, Georgia Sofia Karachaliou, Stratigoula Sakellariou, Ioannis Karavokyros, Maria Gazouli, Dimitrios Schizas
Article Number: 343
Published online on: 02 March 2021

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EZH2 and SMYD3 expression in papillary thyroid cancer

Nadia Sawicka‑Gutaj, Sara Shawkat, Mirosław Andrusiewicz, Paulina Ziółkowska, Agata Czarnywojtek, Paweł Gut, Marek Ruchała
Article Number: 342
Published online on: 02 March 2021

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Case Report

Occurrence of quadruple squamous cell carcinoma following allogeneic hematopoietic stem cell transplantation for leukemia: A case report

Chunhong Hu, Xue Wang, Yue Pan, Long Shu, Fang Wu
Article Number: 341
Published online on: 02 March 2021

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Article Open Access

Decitabine inhibits the proliferation of human T‑cell acute lymphoblastic leukemia molt4 cells and promotes apoptosis partly by regulating the PI3K/AKT/mTOR pathway

Gang Zhang, Xiaohui Gao, Xiaoyan Zhao, Haibing Wu, Minchao Yan, Yuan Li, Hui Zeng, Zhaoning Ji, Xiaojun Guo
Article Number: 340
Published online on: 02 March 2021

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Journal Cover
March-2026 Volume 31 Issue 3

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Immune microenvironment and treatment response of dMMR gastric cancer: Heterogeneity and implications for immunotherapy

Liping Wang, Xinliang Zhong, Mengxing Diao, Wei Deng
Article Number: 119
Published online on: 27 January 2026

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[Retracted] MicroRNA‑150 upregulation reduces osteosarcoma cell invasion and metastasis by downregulating Ezrin

Ce Zhan, Cheng Li, Hao Zhang, Hao Tang, Fang Ji, Su-Chi Qiao, Wei-Dong Xu, Zhi-Wei Wang
Article Number: 118
Published online on: 26 January 2026

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Unveiling mitochondrial DNA copy number alterations: Insights into progression from cervical intraepithelial neoplasia to cervical cancer

İzzet Özgürlük, Haktan Bağış Erdem, Mustafa Tarık Alay, Okan Oktar, Firdevs Şahin-Duran, Ezgi Çevik‑Demir, Aysu Yeşim Tezcan, Hüseyin Levent Keskin
Article Number: 117
Published online on: 23 January 2026

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Case Report Open Access

Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report

Nobuhito Hara, Yumi Yoshii, Yoshiki Kojitani, Rika Sasaki, Masahide Ota, Shunsuke Okazaki, Hitoshi Nakagawa, Junichi Takemura, Ryo Miyata, Masatsugu Hamaji, Mitsuharu Hosono, Fumi Okada, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 116
Published online on: 22 January 2026

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Case Report Open Access

Epithelioid and spindle cell rhabdomyosarcoma of the rib with FUS‑TFCP2 fusion: A case report and literature review

Danli Ye, Min Wu, Jiawen Zong, Weipeng Zeng, Guangning Yan, Juan Zhou, Wei Wang
Article Number: 115
Published online on: 20 January 2026

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Article Open Access

NDC80 kinetochore complex component is a potential molecular target of adenoid cystic carcinoma

Xia Yan, Sumei He, Yuansheng Lin, Jin Zhang, Jian Huan, Haibo Chen, Lina Lu
Article Number: 114
Published online on: 20 January 2026

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Retraction Open Access

[Retracted] MicroRNA‑429 inhibits gastric cancer migration and invasion through the downregulation of specificity protein 1

Jingbin Ni, Yisha Yang, Di Liu, Hui Sun, Shimao Jin, Jingying Li
Article Number: 113
Published online on: 19 January 2026

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Review Open Access

Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome (Review)

Hanyue Ying, Ke Zhang, Yu Chen, Qinghua Deng, Chun Mao, Jiawei Li
Article Number: 112
Published online on: 19 January 2026

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Endostar combined with docetaxel or cisplatin in the management of malignant ascites through hyperthermic intraperitoneal chemotherapy: A retrospective cohort study

Jing Wu, Dashan Yin, Jin Qian, Yi Zhou, Yajun Wu, Ganlu Zhang
Article Number: 111
Published online on: 14 January 2026

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Review

 Three‑dimensional culture of tumor cells (Review)

Shiyao Du, Jinyu Yang, Hui Li, Shanshan Men, Dongping Xu, Haifeng Wang
Article Number: 110
Published online on: 15 January 2026

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Article Open Access

Cytotoxic, apoptotic and genotoxic effects of thymoquinone‑oxime derivative on gastric cancer cells: An in vitro study

Kübra Bozali̇, Zeynep İnce, Nurhi̇lal Kiziltoprak, Taygun Gülşen, Mehmet Köstek, Yasi̇r Musa Kesgi̇n, Muhammer Ergenç, Mi̇ne Dağgez, Eren Altun, Fati̇h Taşkesen, Cebrai̇l Akyüz, Oğuzhan Sunamak, Mustafa Duman, Eray Meti̇n Güler
Article Number: 109
Published online on: 14 January 2026

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Review Open Access

Tumor microenvironment in gastric cancer immune tolerance and its therapeutic relevance in immunomodulation (Review)

Zihe Guan, Lichao Han, Baojiang Chen, Yijia Ma, Qianyue Ni, Zijian Wang, Jingyu Yang, Zheng Liu
Article Number: 108
Published online on: 13 January 2026

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Phosphorylated‑EGFR and MMP7 upregulation in gastric cancer: Association with metastasis and poor prognosis

Biran Ding, Yiqiu Wan, Yao Wu, Zhan Zhang, Ying Ma, Zuo Wang, Runqiu Jiang, Tao Li
Article Number: 107
Published online on: 14 January 2026

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Study on the expression level of folate receptor γ in thyroid cancer and its association with clinicopathological characteristics

Jinying Cao, Yanxu Li, Xin Deng, Bo Lv, Ling Han, Ling Tong
Article Number: 106
Published online on: 12 January 2026

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Prognostic value of glioma‑associated oncogene homolog 1 and SET domain‑containing protein 2 immunohistochemical scores in locally advanced cervical cancer

Erick De La Cruz‑Hernández, Gabriela Carolina Morales‑Sandoval, Marcela Lizano, Alejandro Avilés‑Salas, Leonardo Josué Castro‑Muñoz, Adela Carrillo‑García, Maria Del Pilar Ramos‑Godinez, Jaime Alberto Coronel‑Martinez, Adriana Contreras‑Paredes
Article Number: 105
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Clinical significance of bromodomain‑containing protein 7 and its association with tumor progression in prostate cancer

Yong Liang, Baiping Dong, Jiangwei Shen, Caosheng Ma, Zhongping Ma
Article Number: 104
Published online on: 12 January 2026

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Article Open Access

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance

Cairong Zhang, Jie Ma, Wenling Wang, Min Guo, Cuiliu Han, Madinamu Sadike, Kaichun Zhu
Article Number: 103
Published online on: 12 January 2026

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Circular RNA hsa_circ_0006168: A potential biomarker for the diagnosis and prognosis of prostate cancer

Ye Ding, Mao-Tong Liu, Na Yu, Liusijie Gao, Li-Ping Chen
Article Number: 102
Published online on: 09 January 2026

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Article Open Access

Meta‑analysis of the clinical efficacy of anti‑PD‑1/L1 + paclitaxel/albumin‑paclitaxel + platinum vs. paclitaxel/albumin‑paclitaxel + platinum in the treatment of patients with advanced non‑small cell lung cancer

Feng Li, Suyun Yan, Liping Liu
Article Number: 101
Published online on: 09 January 2026

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Review Open Access

Progress in perioperative immunotherapy for lung cancer and analysis of therapy (Review)

Xiao Ma, Gaofeng Li, Heng Li, Lanjun Li, Hanting Zhao, Zhiqing Liu
Article Number: 100
Published online on: 09 January 2026

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Correction Open Access

[Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells

Xia Chen, Hua Guan, Xiao-Dan Liu, Da-Fei Xie, Yu Wang, Teng Ma, Bo Huang, Ping-Kun Zhou
Article Number: 99
Published online on: 08 January 2026

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Case Report Open Access

High‑intensity focused ultrasound in the multimodal treatment of colorectal cancer liver metastases: A case report

Yuanhong Yang, Hao Zhang, Yifan Shen, Fan Yang, Dan Zhao, Yujie Lin, Guohua Huang
Article Number: 98
Published online on: 07 January 2026

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Article Open Access

Exosomal microRNA‑448 suppresses the malignant behaviors of liver cancer cells by targeting RAB7A and inhibiting glycolysis

Yuankun Chen, Tiantian Zhu, Fang Chen, Mingyue Niu, Haifeng Wu, Qiuping Wu, Zheng Wang, Wenting Li
Article Number: 97
Published online on: 07 January 2026

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Article

Diagnostic value of magnetic resonance imaging in preoperative evaluation of cervical cancer and analysis of pathological features

Xiaofei Cai, Xinjian Lu, Jinjun Yang, Xinxue Wei, Wenjing Yue, Yunqing Ban
Article Number: 96
Published online on: 07 January 2026

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Retraction Open Access

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk‑ChA‑1 and Mz‑ChA‑1 cell growth by inducing caspase‑dependent apoptosis and downregulation of survivin and Bcl‑2 expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li
Article Number: 95
Published online on: 07 January 2026

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Article Open Access

Prognosis of liver transplantation and hepatectomy in patients with hepatocellular carcinoma meeting the Milan criteria: A systematic review and meta‑analysis

Jiling Wang, Zheng Pan, Yongzheng Wang, Yanshuo Ye, Wei Li
Article Number: 94
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen
Article Number: 126
Published online on: 03 February 2026

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Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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