[Corrigendum] Ras‑related protein Rap2c promotes the migration and invasion of human osteosarcoma cells

• Authors:
  • Jinxia Wu
  • Wenqi Du
  • Xiucun Wang
  • Lulu Wei
  • Yaojie Pan
  • Xiaojin Wu
  • Jinling Zhang
  • Dongsheng Pei

• View Affiliations

  
  Affiliations: Department of Physiology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China, Jiangsu Key Laboratory of Biological Cancer Therapy, Xuzhou, Jiangsu 221002, P.R. China, Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu 221000, P.R. China, Department of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China, Department of Radiation Oncology, The First People's Hospital of Xuzhou, Xuzhou, Jiangsu 221002, P.R. China, Department of Oncology, LinYi People's Hospital Affiliated to Shandong University, Jinan, Shandong 250012, P.R. China
• Published online on: April 12, 2021     https://doi.org/10.3892/ol.2021.12723
• Article Number: 462

• Copyright : © Wu et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

Article

Oncol Lett 15: [Related article:] 5352-5358, 2018; DOI: 10.3892/ol.2018.7987

Subsequently to the publication of this paper, an interested reader drew to the authors’ attention that two pairs of data panels in Fig. 3C appeared to contain overlapping data (comparing between the si-Ctrl/si-Rap2c#2 and the Vector/Rap2c panels).

Figure 3. Effect of Rap2c overexpression and knockdown on the invasion and migration of U2OS cells. (A) Wound-healing assays were performed in U2OS cells transfected with a Rap2c expression plasmid or siRNA (magnification, ×100). *P<0.05 vs. si-Ctrl; **P<0.01 vs. Vector. (B) Cell migration was performed following transfection with siRNA or a pcDNA3.1-Rap2c expression plasmid (magnification, ×100). *P<0.05 vs. si-Ctrl or Vector. (C) Cell invasion was measured following transfection with Rap2c expression plasmids or siRNA (magnification, ×100). *P<0.05 vs. si-Ctrl or Vector. (D) The relative enzyme activity of cleaved-MMP2 was measured by a gelatin zymography assay following transfection with siRNA or a Rap2c expression plasmid. **P<0.01 vs. si-Ctrl or Vector. siRNA, small interfering RNA; MMP2, matrix metalloproteinase-2; Ctrl, control; Vector, empty vector.

The authors have re-examined their original data and realized that the Vector and the Rap2c data panels for Fig. 3C were selected incorrectly. The revised version of Fig. 3, containing the correct data for the Vector and the Rap2c experiments in Fig. 3C, is shown below. The authors regret the inadvertent errors that were made in the preparation of the published figure, and confirm that these errors did not seriously affect the conclusions reported in the paper. The authors are grateful to the editor of Oncology Letters for allowing them the opportunity to publish a Corrigendum, and all the authors agree to this Corrigendum. Furthermore, they apologize to the readership for any inconvenience caused.