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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2021 Volume 21 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

MicroRNA‑665 regulates the proliferation, apoptosis and adhesion of gastric cancer cells by binding to cadherin 3

Xinhui Fang, Yangqiu Bai, Lida Zhang, Songze Ding
Article Number: 494
Published online on: 26 April 2021

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Article Open Access

HOXA11‑AS induces cisplatin resistance by modulating the microRNA‑98/PBX3 axis in nasopharyngeal carcinoma

Haineng Li, Jia Huang, Sa Yu, Hangbo Li, Yan Zhou, Qingwei Wu
Article Number: 493
Published online on: 26 April 2021

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Article Open Access

Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis

Sung-Hyun Kim, Gang-Sik Choo, Eun-Seon Yoo, Joong-Seok Woo, Jae-Han Lee, So-Hee Han, Soo-Hyun Jung, Hyeong-Jin Kim, Ji-Youn Jung
Article Number: 492
Published online on: 26 April 2021

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Article Open Access

Expression pattern of histone lysine‑specific demethylase 6B in gastric cancer

Shujun Wang, Yiping Wang, Hui Zhu, Miaohui Chen, Liang Zhang
Article Number: 491
Published online on: 26 April 2021

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Article Open Access

Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer Retraction in /10.3892/ol.2021.13061

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue
Article Number: 490
Published online on: 23 April 2021

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Article Open Access

The effectiveness of plasma miR‑33a‑5p as a predictive biomarker for the efficacy of colorectal cancer chemotherapy

Megumi Sasaki, Toshiaki Ishikawa, Megumi Ishiguro, Satoshi Okazaki, Shinichi Yamauchi, Akifumi Kikuchi, Takatoshi Matsuyama, Kenro Kawada, Masanori Tokunaga, Hiroyuki Uetake, Yusuke Kinugasa
Article Number: 489
Published online on: 22 April 2021

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Article Open Access

Upregulation of glucosamine‑phosphate N‑acetyltransferase 1 is a promising diagnostic and predictive indicator for poor survival in patients with lung adenocarcinoma

Pengyuan Zhu, Shaorui Gu, Haitao Huang, Chongjun Zhong, Zhenchuan Liu, Xin Zhang, Wenli Wang, Shiliang Xie, Kaiqin Wu, Tiancheng Lu, Yongxin Zhou
Article Number: 488
Published online on: 22 April 2021

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Article Open Access

Predictive effects of preoperative serum CA125 and AFP levels on post‑hepatectomy survival in patients with hepatitis B‑related hepatocellular carcinoma

Chuang Qin, Yan Gao, Jiangfa Li, Chao Huang, Songqing He
Article Number: 487
Published online on: 22 April 2021

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Article Open Access

Circular RNA UBAP2 promotes the proliferation of prostate cancer cells via the miR‑1244/MAP3K2 axis

Xiaodong Li, Baihetiya Azhati, Wenguang Wang, Mulati Rexiati, Chen Xing, Yujie Wang
Article Number: 486
Published online on: 21 April 2021

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Article Open Access

SPARC promotes pancreatic cancer cell proliferation and migration through autocrine secretion into the extracellular milieu

Kehua Pan, Xince Huang, Xiufen Jia
Article Number: 485
Published online on: 21 April 2021

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Article Open Access

Krüppel‑like factor 5 is upregulated and induces cell proliferation in endometrial cancer

Tetsuya Moritake, Junya Kojima, Kaiyu Kubota, Fumitoshi Terauchi, Keiichi Isaka, Hirotaka Nishi
Article Number: 484
Published online on: 21 April 2021

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Article Open Access

GAD1 expression and its methylation as indicators of malignant behavior in thymic epithelial tumors

Shiho Soejima, Kazuya Kondo, Mitsuhiro Tsuboi, Kyoka Muguruma, Bilguun Tegshee, Yukikiyo Kawakami, Koichiro Kajiura, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku
Article Number: 483
Published online on: 21 April 2021

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Article Open Access

MicroRNA‑204 plays a role as a tumor suppressor in Newcastle disease virus‑induced oncolysis in lung cancer A549 cells

Ying Liang, Wen-Yu Tian, Juan-Juan Huang, Ling-Xi Gao, Xiao-Hui Fan
Article Number: 482
Published online on: 21 April 2021

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Article

miR‑188‑5p promotes oxaliplatin resistance by targeting RASA1 in colon cancer cells

Xijia Zhu, Xishun Luo, Zhike Song, Shiyu Jiang, Xiangkai Long, Xueyuan Gao, Xinyang Xie, Laijian Zheng, Haipeng Wang
Article Number: 481
Published online on: 20 April 2021

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Correction Open Access

[Corrigendum] Chemopreventive effect of 4'‑hydroxychalcone on intestinal tumorigenesis in ApcMin mice

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge
Article Number: 480
Published online on: 20 April 2021

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Article Open Access

Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis

Mehtap Kilic Eren, Nur Betül Kartal, Hatice Pi̇levneli̇
Article Number: 479
Published online on: 19 April 2021

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Article Open Access

Low CFB expression is independently associated with poor overall and disease‑free survival in patients with lung adenocarcinoma

Chenglu He, Ya Li, Ruixian Zhang, Jing Chen, Xingxing Feng, Yong Duan
Article Number: 478
Published online on: 19 April 2021

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Article Open Access

Incaspitolide A isolated from Carpesium cernuum L. inhibits the growth of prostate cancer cells and induces apoptosis via regulation of the PI3K/Akt/xIAP pathway

Yuanshe Huang, Jingxin Mao, Lai Zhang, Hongwei Guo, Chen Yan, Min Chen
Article Number: 477
Published online on: 19 April 2021

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Article Open Access

Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis

Xuemei Huang, Chunfeng Liang, Haiyan Yang, Xin Li, Xiujun Deng, Xinghuan Liang, Li Li, Zhenxing Huang, Decheng Lu, Yan Ma, Zuojie Luo
Article Number: 476
Published online on: 15 April 2021

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Article Open Access

Analysis of the association between KIN17 expression and the clinical features/prognosis of epithelial ovarian cancer, and the effects of KIN17 in SKOV3 cells

Junyu Chen, Yang Xia, Yuanqing Peng, Shan Wu, Wei Liu, Haoxian Zhang, Tian Wang, Zhaoyun Yang, Shuhua Zhao, Lijing Zhao
Article Number: 475
Published online on: 15 April 2021

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Article Open Access

MicroRNA‑1226‑3p has a tumor‑promoting role in osteosarcoma

Yong Li, Dai Song, Ting An, Jie Liu, Qian Yang, Shaokui Nan
Article Number: 474
Published online on: 15 April 2021

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Article Open Access

Novel brd4 inhibitors with a unique scaffold exhibit antitumor effects

Young Hun Kim, Minsung Kim, Ji Eun Kim, Miyoun Yoo, Heung Kyoung Lee, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Yeongrin Kim, Sang Un Choi, Chi Hoon Park
Article Number: 473
Published online on: 14 April 2021

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Article Open Access

Long non‑coding RNA SNHG17 enhances the aggressiveness of C4‑2 human prostate cancer cells in association with β‑catenin signaling

Haijun Zhao, Haijing Dong, Peng Wang, Hai Zhu
Article Number: 472
Published online on: 13 April 2021

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Article Open Access

lncRNA PCAT6 facilitates cell proliferation and invasion via regulating the miR‑326/hnRNPA2B1 axis in liver cancer

Jun Luo, Jiaping Zheng, Weiyuan Hao, Hui Zeng, Zhewei Zhang, Guoliang Shao
Article Number: 471
Published online on: 13 April 2021

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Article Open Access

LACTB and LC3 could serve as potential biomarkers of gastric cancer to neoadjuvant chemotherapy with oxaliplatin plus S‑1

Fang Yang, Zhiqiang Yan, Wei Nie, Zeying Liu, Xingzhen Cheng, Wei Wang, Chunyan Shao, Gui Fu, Yanni Yu
Article Number: 470
Published online on: 13 April 2021

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Article Open Access

Effect of the circCDR1as/miR‑641/XIAP regulatory axis on the proliferation and invasion of the prostate cancer PC‑3 cell line

Yulin Niu, Jin Hua He, Yinglian Zhang, Kun Li, Chungen Xing
Article Number: 469
Published online on: 13 April 2021

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Article Open Access

DNA methylation variations in familial female and male breast cancer

Edoardo Abeni, Ilaria Grossi, Eleonora Marchina, Arianna Coniglio, Paolo Incardona, Pietro Cavalli, Fausto Zorzi, Pier Luigi Chiodera, Carlo Terenzio Paties, Marialuisa Crosatti, Giuseppina De Petro, Alessandro Salvi
Article Number: 468
Published online on: 12 April 2021

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Review Open Access

Current status of extended ‘D2 plus’ lymphadenectomy in advanced gastric cancer (Review)

Jing-Quan Li, Donglei He, Yue-Xiang Liang
Article Number: 467
Published online on: 12 April 2021

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Article

Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases

Akio Shiomi, Masatoshi Kusuhara, Takashi Sugino, Teiichi Sugiura, Keiichi Ohshima, Takeshi Nagashima, Kenichi Urakami, Masakuni Serizawa, Hideyuki Saya, Ken Yamaguchi
Article Number: 466
Published online on: 12 April 2021

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Review Open Access

Regulatory function of peroxiredoxin I on 4‑(methylnitrosamino)‑1‑(3‑pyridyl)‑1‑butanone‑induced lung cancer development (Review)

Hu-Nan Sun, Chen-Xi Ren, Yi-Xi Gong, Dan-Ping Xie, Taeho Kwon
Article Number: 465
Published online on: 12 April 2021

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Article Open Access

Upregulation of long‑noncoding RNA PTPRG‑AS1 can predict the poor prognosis and promote migration and invasion in patients with osteosarcoma

Rile Ge, Peng Yang, Bingtao Wen
Article Number: 464
Published online on: 12 April 2021

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Retraction Open Access

[Retracted] Biochanin A induces anticancer effects in SK‑Mel‑28 human malignant melanoma cells via induction of apoptosis, inhibition of cell invasion and modulation of NF‑κB and MAPK signaling pathways

Peng Xiao, Bowen Zheng, Jiaming Sun, Jia Yang
Article Number: 463
Published online on: 12 April 2021

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Correction Open Access

[Corrigendum] Ras‑related protein Rap2c promotes the migration and invasion of human osteosarcoma cells

Jinxia Wu, Wenqi Du, Xiucun Wang, Lulu Wei, Yaojie Pan, Xiaojin Wu, Jinling Zhang, Dongsheng Pei
Article Number: 462
Published online on: 12 April 2021

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Article Open Access

PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma

Jia Luo, Lei Zhang, Lijuan Guo, Sen Yang
Article Number: 461
Published online on: 11 April 2021

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Review Open Access

Role of aryl hydrocarbon receptor in central nervous system tumors: Biological and therapeutic implications (Review)

Montserrat Zaragoza‑Ojeda, Elisa Apatiga‑Vega, Francisco Arenas‑Huertero
Article Number: 460
Published online on: 11 April 2021

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Article Open Access

miR‑574‑5p mediates epithelial‑mesenchymal transition in small cell lung cancer by targeting vimentin via a competitive endogenous RNA network

Yanqin Sun, Yanmei Yi, Siyuan Gan, Ruifang Ye, Cailing Huang, Man Li, Jian Huang, Ying Guo
Article Number: 459
Published online on: 08 April 2021

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Article Open Access

Inhibition of aquaporins as a potential adjunct to breast cancer cryotherapy

Haifa Alkhalifa, Fatima Mohammed, Sebastien Taurin, Khaled Greish, Safa Taha, Salim Fredericks
Article Number: 458
Published online on: 08 April 2021

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Article

MicroRNA‑133a‑3p suppresses malignant behavior of non‑small cell lung cancer cells by negatively regulating ERBB2

Yanhui Xu, Lei Zhang, Lilong Xia, Xinhai Zhu
Article Number: 457
Published online on: 08 April 2021

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Article Open Access

Integrative analysis of the gastric cancer long non‑coding RNA‑associated competing endogenous RNA network

Yuyou Jiang, Xianqin Zhang, Li Rong, Yi Hou, Jing Song, Wanfeng Zhang, Min He, Yan Xie, Yue Li, Fangzhou Song
Article Number: 456
Published online on: 08 April 2021

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Article Open Access

lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma Corrigendum in /10.3892/ol.2021.12959

Hideharu Yamada, Masanobu Takahashi, Munenori Watanuki, Mika Watanabe, Sakura Hiraide, Ken Saijo, Keigo Komine, Chikashi Ishioka
Article Number: 455
Published online on: 08 April 2021

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Article Open Access

Prognosis of patients treated in a single neurosurgical reference centre for brain metastasis caused by dormant disseminated cells

Lorenzo Ferlini, Lorenzo Peluso, Valentina Lolli, Nicolas Gaspard, Florence Lefranc
Article Number: 454
Published online on: 08 April 2021

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Article Open Access

Daphnoretin induces reactive oxygen species‑mediated apoptosis in melanoma cells

Hui Wang, Xue Hu, Minjing Li, Zhaohai Pan, Defang Li, Qiusheng Zheng
Article Number: 453
Published online on: 08 April 2021

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Article

Ginsenoside Rg5 inhibits cancer cell migration by inhibiting the nuclear factor‑κB and erythropoietin‑producing hepatocellular receptor A2 signaling pathways

Leixin Song, Fan Yang, Zhengtao Wang, Li Yang, Yue Zhou
Article Number: 452
Published online on: 08 April 2021

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Review Open Access

Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs (Review)

Zhangming Chen, Jie Hu, Songcheng Ying, Aman Xu
Article Number: 451
Published online on: 08 April 2021

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Article Open Access

Excision repair cross‑complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence

Yen-Yun Wang, Pen-Tzu Fang, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang, Shyng-Shiou F. Yuan
Article Number: 450
Published online on: 07 April 2021

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Article Open Access

Impact of copy number variant and single nucleotide polymorphism of the programmed death‑ligand 1 gene, programmed death‑ligand 1 protein expression and therapy regimens on overall survival in a large group of Caucasian patients with non‑small cell lung carcinoma

Anna Grenda, Paweł Krawczyk, Tomasz Kucharczyk, Justyna Błach, Katarzyna Reszka, Izabela Chmielewska, Jarosław Buczkowski, Robert Kieszko, Jan Siwiec, Tomasz Kubiatowski, Aleksandra Bożyk, Kinga Krukowska, Bożena Jarosz, Iwona Paśnik, Juliusz Pankowski, Daria Świniuch, Katarzyna Stencel, Michał Gil, Kinga Lew, Rodryg Ramlau, Aleksandra Szczęsna, Sebastian Fidler, Andrzej Sieracki, Andrzej Każarnowicz, Piotr Serwatowski, Tomasz Grodzki, Janusz Milanowski
Article Number: 449
Published online on: 07 April 2021

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Article

Impact of EGFR and EGFR ligand expression on treatment response in patients with metastatic colorectal cancer

Fee Klupp, Malte Sass, Frank Bergmann, Elias Khajeh, Omid Ghamarnejad, Matthias Hassenpflug, Arianeb Mehrabi, Yakup Kulu
Article Number: 448
Published online on: 07 April 2021

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Article Open Access

Clinical value of lncRNA CCAT1 in serum extracellular vesicles as a potential biomarker for gastric cancer

Ke Xiao, Zhaogang Dong, Ding Wang, Min Liu, Juan Ding, Wendan Chen, Ziqi Shang, Congbo Yue, Yi Zhang
Article Number: 447
Published online on: 06 April 2021

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Article

Analysis of radiotherapy‑induced alteration of CD8+ T cells and PD‑L1 expression in patients with uterine cervical squamous cell carcinoma

Yasumasa Mori, Hiro Sato, Takuya Kumazawa, Tiara Bunga Mayang Permata, Yuya Yoshimoto, Kazutoshi Murata, Shin-Ei Noda, Takuya Kaminuma, Ken Ando, Takahiro Oike, Noriyuki Okonogi, Kohei Okada, Sangeeta Kakoti, Keiji Suzuki, Hayato Ikota, Hideaki Yokoo, Takashi Nakano, Tatsuya Ohno, Atsushi Shibata
Article Number: 446
Published online on: 06 April 2021

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Article Open Access

Stromal expression of cancer‑associated fibroblast‑related molecules, versican and lumican, is strongly associated with worse relapse‑free and overall survival times in patients with esophageal squamous cell carcinoma

Naoto Yamauchi, Yasuyuki Kanke, Katsuharu Saito, Hirokazu Okayama, Shoki Yamada, Shotaro Nakajima, Eisei Endo, Koji Kase, Leo Yamada, Hiroshi Nakano, Takuro Matsumoto, Hiroyuki Hanayama, Yohei Watanabe, Suguru Hayase, Motonobu Saito, Zenichiro Saze, Kosaku Mimura, Tomoyuki Momma, Shinji Oki, Yuko Hashimoto, Koji Kono
Article Number: 445
Published online on: 06 April 2021

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Article Open Access

Long non‑coding RNA HOTAIR promotes the progression of synovial sarcoma through microRNA‑126/stromal cell‑derived factor‑1 regulation

Qi Feng, Donglai Wang, Peng Guo, Zibo Zhang, Jiangang Feng
Article Number: 444
Published online on: 06 April 2021

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Article Open Access

Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma

I-Neng Lee, Jen-Tsung Yang, Cheng Huang, Hsiu-Chen Huang, Yu-Ping Wu, Jui-Chieh Chen
Article Number: 443
Published online on: 06 April 2021

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Article Open Access

LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β‑catenin signaling pathway and epithelial‑mesenchymal transition

Min Xu, Bangyi Lin, Danni Zheng, Jialiang Wen, Wenjing Hu, Chunxue Li, Xianwei Zhang, Xiaohua Zhang, Jinmiao Qu
Article Number: 442
Published online on: 02 April 2021

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Article Open Access

Expression profiling of CPS1 in Correa's cascade and its association with gastric cancer prognosis

Xuqian Fang, Xiaoqiong Wu, Enfei Xiang, Fangxiu Luo, Qinqin Li, Qianchen Ma, Fei Yuan, Peizhan Chen
Article Number: 441
Published online on: 02 April 2021

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Article Open Access

DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression

Mai-Qing Yang, Lin-Lin Bai, Zhao Wang, Lei Lei, Yi-Wen Zheng, Zhi-Han Li, Wen-Jing Huang, Chen-Chen Liu, Hong-Tao Xu
Article Number: 440
Published online on: 01 April 2021

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Review Open Access

Potential role of mitochondria in gastric cancer detection: Fission and glycolysis (Review)

Hang Yang, Yan Li, Bing Hu
Article Number: 439
Published online on: 01 April 2021

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Article Open Access

Recombinant protein TRAIL-Mu3 enhances the antitumor effects in pancreatic cancer cells by strengthening the apoptotic signaling pathway

Min Huang, Cheng Yi, Xian-Zhou Huang, Juan Yan, Li-Jia Wei, Wei-Ju Tang, Shou-Chun Chen, Ying Huang
Article Number: 438
Published online on: 01 April 2021

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Aquaporin 1 knockdown inhibits triple‑negative breast cancer cell proliferation and invasion in vitro and in vivo

Yinan Ji, Xiaoming Liao, Yi Jiang, Wei Wei, Huawei Yang
Article Number: 437
Published online on: 01 April 2021

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Ring finger 20/ring finger 40/WW domain‑containing adaptor with coiled‑coil complex interacts with p53 to regulate gene transcription in DNA damage response

Danni Meng, Kun Guo, Die Zhang, Cheng Zhao, Chuanwen Sun, Feng Zhang
Article Number: 436
Published online on: 01 April 2021

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β‑asarone suppresses HCT116 colon cancer cell proliferation and liver metastasis in part by activating the innate immune system

Min Chen, Yu-Wen Zhuang, Cun-En Wu, Hai-Yan Peng, Jun Qian, Jin-Yong Zhou
Article Number: 435
Published online on: 31 March 2021

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Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 434
Published online on: 31 March 2021

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Lentivirus‑mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial‑mesenchymal transition in lung adenocarcinoma A549 cells

Chun-Sheng Hu, Jiu-Hong Huang, Dong-Lin Yang, Chuan Xu, Zhi-Gang Xu, Hong-Bo Tan, Zhong-Zhu Chen
Article Number: 433
Published online on: 31 March 2021

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Activation of GPER by E2 promotes proliferation, invasion and migration of breast cancer cells by regulating the miR‑124/CD151 pathway Retraction in /10.3892/ol.2025.15429

Huaicheng Yang, Congyu Wang, Heqiang Liao, Qi Wang
Article Number: 432
Published online on: 31 March 2021

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Siomycin A induces reactive oxygen species‑mediated cytotoxicity in ovarian cancer cells

Xiulan Shao, Fengying Zhang, Xiang Gao, Fengying Xu
Article Number: 431
Published online on: 31 March 2021

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Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity in tumor‑related genes in gastric cancer

Xueyun Huo, Xiaoqin Xiao, Shuangyue Zhang, Xiaoyan Du, Changlong Li, Zhigang Bai, Zhenwen Chen
Article Number: 430
Published online on: 30 March 2021

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lncRNA LINC00473 promotes proliferation, migration, invasion and inhibition of apoptosis of non‑small cell lung cancer cells by acting as a sponge of miR‑497‑5p

Shao-Hua Xu, Yu-Hong Bo, Han-Chen Ma, Hua-Nan Zhang, Ming-Ju Shao
Article Number: 429
Published online on: 30 March 2021

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Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures

Birgit Lohberger, Dietmar Glaenzer, Nicole Eck, Bibiane Steinecker-Frohnwieser, Andreas Leithner, Beate Rinner, Sylvia Kerschbaum-Gruber, Dietmar Georg
Article Number: 428
Published online on: 30 March 2021

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

ARID3A knockdown facilitates ferroptosis partly through modulation of the PTEN/Akt pathway in breast cancer

Pengfei Shi, Yan Yi, Maojie Zhang, Yongjun Liu, Ming Jiang, Jiaming Zhang
Article Number: 378
Published online on: 29 June 2026

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A genome‑wide Mendelian randomization study focusing on endoplasmic reticulum stress reveals novel genetic markers for renal cell carcinoma

Bingli Gao, Zhaojun Li, Jihan Shi, Junwen Shen
Article Number: 377
Published online on: 26 June 2026

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Prognostic impact of low skeletal muscle mass in stage I‑III colon cancer: A retrospective study

Chen Mi, Feng Cui, Hanteng Yang
Article Number: 376
Published online on: 26 June 2026

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Superior cancer detection with transperineal biopsy in patients with an elevated prostate‑specific antigen level and a PI‑RADS score of 3‑4: A retrospective cohort study

Jun Zhang, Hui Zheng
Article Number: 375
Published online on: 25 June 2026

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Article

Association between fibroblast activation protein α expression and immune environment in gastric cancer

Kosuke Kubo, Yukinori Kurokawa, Takaomi Hagi, Shinnosuke Nagano, Tsuyoshi Takahashi, Takuro Saito, Kazuyoshi Yamamoto, Kota Momose, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki
Article Number: 374
Published online on: 25 June 2026

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Clinicopathological features and therapeutic advances in primary pulmonary lymphoepithelioma‑like carcinoma (Review)

Yong Chen, Yonglin Yu, Xiaoju Chen
Article Number: 373
Published online on: 25 June 2026

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[Expression of Concern] Myricetin inhibits migration and invasion of hepatocellular carcinoma MHCC97H cell line by inhibiting the EMT process

Hongxin Ma, Lei Zhu, Jingna Ren, Benlong Rao, Maomao Sha, Yi Kuang, Weigan Shen, Zhengxin Xu
Article Number: 372
Published online on: 24 June 2026

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FBXL5 depletion as a novel strategy against osteosarcoma: Evidence for MEK/ERK inhibition and enhanced therapeutic sensitivity

Yan-Chao Ma, Wen-Ming Zhou, Yong-Qiang Shi, Yan-Bo Dong, Hai-Hong Zhang, Wei Nan
Article Number: 371
Published online on: 24 June 2026

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Special Issue

Androgen receptor drives lenvatinib resistance in hepatocellular carcinoma through transcriptional activation of EIF3I and a downstream ceRNA axis

Changfeng Liu, Bing Zhang, Ye Jin, Zhi Chen, Miaomiao Wang, Zujian Wu
Article Number: 370
Published online on: 24 June 2026

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SUMOylation inhibitor TAK‑981 suppresses proliferation and induces apoptosis in SK‑UT‑1B uterine leiomyosarcoma cells

Hosouk Joung, Hyunju Liu
Article Number: 369
Published online on: 24 June 2026

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Methylation of the BMP6, BRCA1, ESR2, GSTP1 and TIMP3 genes in Mexican women with breast cancer and benign disease

Samantha Rebeca de la Torre-Guzmán, Andrea Marlene García Muro, Brenda Pelayo-Chávez, Carolina Vázquez-Gastélum, Martha Patricia Gallegos-Arreola, Ernesto Soto-Reyes, Sergio Osvaldo Meza-Chavolla, Josefina Yoaly Sánchez-López
Article Number: 368
Published online on: 24 June 2026

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Identification of neoadjuvant chemoradiotherapy resistance‑associated proteins in locally advanced rectal cancer: A pilot study

Jiang-Yi He, Yan Dong, Can Chen, Fang-Hao Lu, Feng-Wei Ran, Qiong Ding, Yun Du, Tao-Rui Liu, Yu-Ying Zhang, Teng Wang, Yu-Han Chen, Xiang Zhao, Sen-Lin Xu, Jian-Jun Li
Article Number: 367
Published online on: 24 June 2026

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Overexpression of EZH2 is associated with clinicopathological parameters and poor prognosis in gliomas

Can Peng, Wei Chen, Jun Yang, Li Wang, Lixia Lu, Rong Ge
Article Number: 366
Published online on: 24 June 2026

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Correction Open Access

[Corrigendum] Wentilactone A induces cell apoptosis by targeting AKR1C1 gene via the IGF‑1R/IRS1/PI3K/AKT/Nrf2/FLIP/Caspase‑3 signaling pathway in small cell lung cancer

Wenli Jiang, Linghong Meng, Guangming Xu, Cuiting Lv, Hongliang Wang, He Tian, Ruohua Chen, Binghua Jiao, Bingui Wang, Caiguo Huang
Article Number: 365
Published online on: 22 June 2026

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A HRH1‑YAP1 feedback loop drives pancreatic cancer progression and predicts therapeutic response

Junliang Chen, Jun Wen
Article Number: 364
Published online on: 19 June 2026

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Case Report Open Access

Salivary duct carcinoma with heterotopic ossification in the parotid gland: A case report

Yutaro Fukuma, Mitsuaki Ishida, Akinori Sasaki, Tsuyoshi Jinnin, Tetsuya Terada, Shin-Ichi Haginomori, Yoshinobu Hirose
Article Number: 363
Published online on: 19 June 2026

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Case Report Open Access

Pathological fracture of primary lymphoma of bone: A case report on diagnosis and novel surgical management

Duc Thanh Tran, Van Khanh Nguyen, Tran Quang Sang Nguyen, Minh Quang Dang, Van Anh Nguyen, The Hung Le, Tuyet Thanh Hai Tran, Van Cong Tran, Thi Thu Hien Tran, Trung Dung Tran
Article Number: 362
Published online on: 19 June 2026

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Review Open Access

Application and challenges of chimeric antigen receptor T cell therapy in the treatment of acute myeloid leukemia (Review)

Jingjing Zhang, Feilin Wang, Dandan Sui, Ziyi Huang, Yijian Chen
Article Number: 361
Published online on: 19 June 2026

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Prognostic value of the preoperative lactate dehydrogenase‑to‑albumin ratio in patients with gastrointestinal cancer

Yean Yu, Li Yan, Kun Lv, Tianhui Huang
Article Number: 360
Published online on: 18 June 2026

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Correction Open Access

[Corrigendum] Overexpression of lncRNA AFAP1‑AS1 promotes cell proliferation and invasion in gastric cancer  

Zhouxiao Li, Zhili Ding, Dawei Rong, Weiwei Tang, Hongyong Cao
Article Number: 359
Published online on: 18 June 2026

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Case Report Open Access

Safe management of sequential chemotherapy in a hemodialysis patient with metastatic colorectal cancer: A case report

Rika Sasaki, Nobuhito Hara, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Masayuki Takeda
Article Number: 358
Published online on: 18 June 2026

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Anti‑CD20 and ‑PD‑1 antibody effects on proliferation, apoptosis and cell cycle of endometrial cancer cells

Jinqiu Su, Jiayuan Du, Yaojie Yu, Mei Feng, Qiuyue Huang, Bing Liu, He Wang
Article Number: 357
Published online on: 17 June 2026

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CD47 monoclonal antibody enhances the inhibitory effect of anti‑HER2 chimeric antigen receptor macrophages on ovarian cancer

Jie Qiao, Qing Kou, Ji Qiu
Article Number: 356
Published online on: 17 June 2026

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Correction Open Access

[Corrigendum] Temozolomide abrogates the aggressiveness of urothelial carcinoma cells by enhancing senescence and depleting the side population

Na-Yon Kim, Sung-Hyun Hwang, Yeseul Yang, Yongbaek Kim
Article Number: 355
Published online on: 17 June 2026

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Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Article

Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala-Dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Case Report Open Access

Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Longlong Luo, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Josephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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Journal Cover
September-2026 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

Jinfen Yao, Jie Chen
Article Number: 393
Published online on: 03 July 2026

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Review Open Access

Regulatory roles of N6‑methyladenosine methylation factors in melanoma invasion and metastasis (Review)

Zhijie Xu, Wanqun Yu, Jie Liu, Xiyue Chang, Shiraz Manji Laeeqa, Zerong Xu, Qi Yang, Wanan Xiao
Article Number: 392
Published online on: 03 July 2026

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Review

Microbiota in pancreatic cancer: Roles in tumor initiation and progression (Review)

Yanjun Lou, Yiqun Fan
Article Number: 391
Published online on: 03 July 2026

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Review Open Access

Role of long non‑coding RNA HCG11 in human cancers: From molecular mechanisms to clinical applications (Review)

Qiong-Feng Tan, Bo Chen, Hai-Feng Hu, Huang Liu, Wen Huang, Wei Mu
Article Number: 390
Published online on: 03 July 2026

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Expression of Concern Open Access

[Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma

Yumiko Kondo, Kanya Honoki, Shingo Kishi, Shiori Mori, Rina Fujiwara‑Tani, Shinji Tsukamoto, Hiromasa Fujii, Hiroki Kuniyasu, Yasuhito Tanaka
Article Number: 389
Published online on: 03 July 2026

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Review Open Access

Emerging roles of O‑GlcNAcylation in tumorigenesis, immunosuppression and drug resistance (Review)

Yuntong Liu, Yumo Han, Shumei Ding, Han Deng, Shiyue Li, Yingyu Zhang, Haimeng Yin, Bo You
Article Number: 388
Published online on: 02 July 2026

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Article Open Access

Efficacy and safety of immune checkpoint inhibitors combined with anti‑angiogenic agents for advanced cervical cancer: A systematic review and meta‑analysis

Hengchang Chen, Xue Yang, Yulu Qin, Wentong Xu, Mingzhu Jiao, Xinyu Lu, Yaxu Su, Fengjuan Zhou, Yong Xin
Article Number: 387
Published online on: 02 July 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

Dong Wang, Xiaohou Wu
Article Number: 386
Published online on: 02 July 2026

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Article Open Access

Lymphocyte‑to‑C‑reactive protein ratio as a clinically feasible nutrition‑inflammation marker for predicting outcomes in patients with gastric cancer

Kai Liu, Lai Chang
Article Number: 385
Published online on: 02 July 2026

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Article Open Access

Identification and validation of aging‑related genes in patients with multiple myeloma

Huajing Liu, Senhua Song, Yingtao Wu, Yu Wang, Yueping Liu, Ying Liu
Article Number: 384
Published online on: 02 July 2026

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Retraction Open Access

[Retracted] miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang
Article Number: 383
Published online on: 01 July 2026

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Article Open Access

Air pollution and hepatocellular carcinoma: Integrated network toxicology, machine learning, molecular docking and multiomics analysis

Xiaorong Wang, Huihao Qin, Jing Jing, Yun Liu, Lei Guo, Hongquan Liu, Wei Zhang
Article Number: 382
Published online on: 30 June 2026

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Case Report Open Access

Cervical metastasis in breast cancer: A case report

Xinru Liu, Ke Sun, Hongming Zhu, Tonghua Du, Liyang Sheng, Bin Liu
Article Number: 381
Published online on: 30 June 2026

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Review Open Access

New and emerging strategies for targeting cancers: Challenges and opportunities (Review)

Sreenivasa R. Chinni, Arun K. Rishi, Kaladhar B. Reddy
Article Number: 380
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Article Number: 379
Published online on: 29 June 2026

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