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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2021 Volume 21 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

MicroRNA‑665 regulates the proliferation, apoptosis and adhesion of gastric cancer cells by binding to cadherin 3

Xinhui Fang, Yangqiu Bai, Lida Zhang, Songze Ding
Article Number: 494
Published online on: 26 April 2021

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Article Open Access

HOXA11‑AS induces cisplatin resistance by modulating the microRNA‑98/PBX3 axis in nasopharyngeal carcinoma

Haineng Li, Jia Huang, Sa Yu, Hangbo Li, Yan Zhou, Qingwei Wu
Article Number: 493
Published online on: 26 April 2021

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Article Open Access

Silymarin inhibits proliferation of human breast cancer cells via regulation of the MAPK signaling pathway and induction of apoptosis

Sung-Hyun Kim, Gang-Sik Choo, Eun-Seon Yoo, Joong-Seok Woo, Jae-Han Lee, So-Hee Han, Soo-Hyun Jung, Hyeong-Jin Kim, Ji-Youn Jung
Article Number: 492
Published online on: 26 April 2021

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Article Open Access

Expression pattern of histone lysine‑specific demethylase 6B in gastric cancer

Shujun Wang, Yiping Wang, Hui Zhu, Miaohui Chen, Liang Zhang
Article Number: 491
Published online on: 26 April 2021

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Article Open Access

Oncolytic virotherapy with human telomerase reverse transcriptase promoter regulation enhances cytotoxic effects against gastric cancer Retraction in /10.3892/ol.2021.13061

Tomoya Kato, Mikihito Nakamori, Shuichi Matsumura, Masaki Nakamura, Toshiyasu Ojima, Hiroshi Fukuhara, Yasushi Ino, Tomoki Todo, Hiroki Yamaue
Article Number: 490
Published online on: 23 April 2021

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Article Open Access

The effectiveness of plasma miR‑33a‑5p as a predictive biomarker for the efficacy of colorectal cancer chemotherapy

Megumi Sasaki, Toshiaki Ishikawa, Megumi Ishiguro, Satoshi Okazaki, Shinichi Yamauchi, Akifumi Kikuchi, Takatoshi Matsuyama, Kenro Kawada, Masanori Tokunaga, Hiroyuki Uetake, Yusuke Kinugasa
Article Number: 489
Published online on: 22 April 2021

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Article Open Access

Upregulation of glucosamine‑phosphate N‑acetyltransferase 1 is a promising diagnostic and predictive indicator for poor survival in patients with lung adenocarcinoma

Pengyuan Zhu, Shaorui Gu, Haitao Huang, Chongjun Zhong, Zhenchuan Liu, Xin Zhang, Wenli Wang, Shiliang Xie, Kaiqin Wu, Tiancheng Lu, Yongxin Zhou
Article Number: 488
Published online on: 22 April 2021

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Article Open Access

Predictive effects of preoperative serum CA125 and AFP levels on post‑hepatectomy survival in patients with hepatitis B‑related hepatocellular carcinoma

Chuang Qin, Yan Gao, Jiangfa Li, Chao Huang, Songqing He
Article Number: 487
Published online on: 22 April 2021

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Article Open Access

Circular RNA UBAP2 promotes the proliferation of prostate cancer cells via the miR‑1244/MAP3K2 axis

Xiaodong Li, Baihetiya Azhati, Wenguang Wang, Mulati Rexiati, Chen Xing, Yujie Wang
Article Number: 486
Published online on: 21 April 2021

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Article Open Access

SPARC promotes pancreatic cancer cell proliferation and migration through autocrine secretion into the extracellular milieu

Kehua Pan, Xince Huang, Xiufen Jia
Article Number: 485
Published online on: 21 April 2021

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Article Open Access

Krüppel‑like factor 5 is upregulated and induces cell proliferation in endometrial cancer

Tetsuya Moritake, Junya Kojima, Kaiyu Kubota, Fumitoshi Terauchi, Keiichi Isaka, Hirotaka Nishi
Article Number: 484
Published online on: 21 April 2021

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Article Open Access

GAD1 expression and its methylation as indicators of malignant behavior in thymic epithelial tumors

Shiho Soejima, Kazuya Kondo, Mitsuhiro Tsuboi, Kyoka Muguruma, Bilguun Tegshee, Yukikiyo Kawakami, Koichiro Kajiura, Naoya Kawakita, Hiroaki Toba, Mitsuteru Yoshida, Hiromitsu Takizawa, Akira Tangoku
Article Number: 483
Published online on: 21 April 2021

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Article Open Access

MicroRNA‑204 plays a role as a tumor suppressor in Newcastle disease virus‑induced oncolysis in lung cancer A549 cells

Ying Liang, Wen-Yu Tian, Juan-Juan Huang, Ling-Xi Gao, Xiao-Hui Fan
Article Number: 482
Published online on: 21 April 2021

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Article

miR‑188‑5p promotes oxaliplatin resistance by targeting RASA1 in colon cancer cells

Xijia Zhu, Xishun Luo, Zhike Song, Shiyu Jiang, Xiangkai Long, Xueyuan Gao, Xinyang Xie, Laijian Zheng, Haipeng Wang
Article Number: 481
Published online on: 20 April 2021

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Correction Open Access

[Corrigendum] Chemopreventive effect of 4'‑hydroxychalcone on intestinal tumorigenesis in ApcMin mice

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge
Article Number: 480
Published online on: 20 April 2021

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Article Open Access

Oncogenic WIP1 phosphatase attenuates the DNA damage response and sensitizes p53 mutant Jurkat cells to apoptosis

Mehtap Kilic Eren, Nur Betül Kartal, Hatice Pi̇levneli̇
Article Number: 479
Published online on: 19 April 2021

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Article Open Access

Low CFB expression is independently associated with poor overall and disease‑free survival in patients with lung adenocarcinoma

Chenglu He, Ya Li, Ruixian Zhang, Jing Chen, Xingxing Feng, Yong Duan
Article Number: 478
Published online on: 19 April 2021

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Article Open Access

Incaspitolide A isolated from Carpesium cernuum L. inhibits the growth of prostate cancer cells and induces apoptosis via regulation of the PI3K/Akt/xIAP pathway

Yuanshe Huang, Jingxin Mao, Lai Zhang, Hongwei Guo, Chen Yan, Min Chen
Article Number: 477
Published online on: 19 April 2021

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Article Open Access

Curcumin induces apoptosis and inhibits the growth of adrenocortical carcinoma: Identification of potential candidate genes and pathways by transcriptome analysis

Xuemei Huang, Chunfeng Liang, Haiyan Yang, Xin Li, Xiujun Deng, Xinghuan Liang, Li Li, Zhenxing Huang, Decheng Lu, Yan Ma, Zuojie Luo
Article Number: 476
Published online on: 15 April 2021

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Article Open Access

Analysis of the association between KIN17 expression and the clinical features/prognosis of epithelial ovarian cancer, and the effects of KIN17 in SKOV3 cells

Junyu Chen, Yang Xia, Yuanqing Peng, Shan Wu, Wei Liu, Haoxian Zhang, Tian Wang, Zhaoyun Yang, Shuhua Zhao, Lijing Zhao
Article Number: 475
Published online on: 15 April 2021

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Article Open Access

MicroRNA‑1226‑3p has a tumor‑promoting role in osteosarcoma

Yong Li, Dai Song, Ting An, Jie Liu, Qian Yang, Shaokui Nan
Article Number: 474
Published online on: 15 April 2021

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Article Open Access

Novel brd4 inhibitors with a unique scaffold exhibit antitumor effects

Young Hun Kim, Minsung Kim, Ji Eun Kim, Miyoun Yoo, Heung Kyoung Lee, Chong Ock Lee, Minjin Yoo, Kwan-Young Jung, Yeongrin Kim, Sang Un Choi, Chi Hoon Park
Article Number: 473
Published online on: 14 April 2021

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Article Open Access

Long non‑coding RNA SNHG17 enhances the aggressiveness of C4‑2 human prostate cancer cells in association with β‑catenin signaling

Haijun Zhao, Haijing Dong, Peng Wang, Hai Zhu
Article Number: 472
Published online on: 13 April 2021

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Article Open Access

lncRNA PCAT6 facilitates cell proliferation and invasion via regulating the miR‑326/hnRNPA2B1 axis in liver cancer

Jun Luo, Jiaping Zheng, Weiyuan Hao, Hui Zeng, Zhewei Zhang, Guoliang Shao
Article Number: 471
Published online on: 13 April 2021

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Article Open Access

LACTB and LC3 could serve as potential biomarkers of gastric cancer to neoadjuvant chemotherapy with oxaliplatin plus S‑1

Fang Yang, Zhiqiang Yan, Wei Nie, Zeying Liu, Xingzhen Cheng, Wei Wang, Chunyan Shao, Gui Fu, Yanni Yu
Article Number: 470
Published online on: 13 April 2021

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Article Open Access

Effect of the circCDR1as/miR‑641/XIAP regulatory axis on the proliferation and invasion of the prostate cancer PC‑3 cell line

Yulin Niu, Jin Hua He, Yinglian Zhang, Kun Li, Chungen Xing
Article Number: 469
Published online on: 13 April 2021

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Article Open Access

DNA methylation variations in familial female and male breast cancer

Edoardo Abeni, Ilaria Grossi, Eleonora Marchina, Arianna Coniglio, Paolo Incardona, Pietro Cavalli, Fausto Zorzi, Pier Luigi Chiodera, Carlo Terenzio Paties, Marialuisa Crosatti, Giuseppina De Petro, Alessandro Salvi
Article Number: 468
Published online on: 12 April 2021

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Review Open Access

Current status of extended ‘D2 plus’ lymphadenectomy in advanced gastric cancer (Review)

Jing-Quan Li, Donglei He, Yue-Xiang Liang
Article Number: 467
Published online on: 12 April 2021

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Article

Comprehensive genomic analysis contrasting primary colorectal cancer and matched liver metastases

Akio Shiomi, Masatoshi Kusuhara, Takashi Sugino, Teiichi Sugiura, Keiichi Ohshima, Takeshi Nagashima, Kenichi Urakami, Masakuni Serizawa, Hideyuki Saya, Ken Yamaguchi
Article Number: 466
Published online on: 12 April 2021

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Review Open Access

Regulatory function of peroxiredoxin I on 4‑(methylnitrosamino)‑1‑(3‑pyridyl)‑1‑butanone‑induced lung cancer development (Review)

Hu-Nan Sun, Chen-Xi Ren, Yi-Xi Gong, Dan-Ping Xie, Taeho Kwon
Article Number: 465
Published online on: 12 April 2021

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Article Open Access

Upregulation of long‑noncoding RNA PTPRG‑AS1 can predict the poor prognosis and promote migration and invasion in patients with osteosarcoma

Rile Ge, Peng Yang, Bingtao Wen
Article Number: 464
Published online on: 12 April 2021

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Retraction Open Access

[Retracted] Biochanin A induces anticancer effects in SK‑Mel‑28 human malignant melanoma cells via induction of apoptosis, inhibition of cell invasion and modulation of NF‑κB and MAPK signaling pathways

Peng Xiao, Bowen Zheng, Jiaming Sun, Jia Yang
Article Number: 463
Published online on: 12 April 2021

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Correction Open Access

[Corrigendum] Ras‑related protein Rap2c promotes the migration and invasion of human osteosarcoma cells

Jinxia Wu, Wenqi Du, Xiucun Wang, Lulu Wei, Yaojie Pan, Xiaojin Wu, Jinling Zhang, Dongsheng Pei
Article Number: 462
Published online on: 12 April 2021

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Article Open Access

PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma

Jia Luo, Lei Zhang, Lijuan Guo, Sen Yang
Article Number: 461
Published online on: 11 April 2021

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Review Open Access

Role of aryl hydrocarbon receptor in central nervous system tumors: Biological and therapeutic implications (Review)

Montserrat Zaragoza‑Ojeda, Elisa Apatiga‑Vega, Francisco Arenas‑Huertero
Article Number: 460
Published online on: 11 April 2021

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Article Open Access

miR‑574‑5p mediates epithelial‑mesenchymal transition in small cell lung cancer by targeting vimentin via a competitive endogenous RNA network

Yanqin Sun, Yanmei Yi, Siyuan Gan, Ruifang Ye, Cailing Huang, Man Li, Jian Huang, Ying Guo
Article Number: 459
Published online on: 08 April 2021

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Article Open Access

Inhibition of aquaporins as a potential adjunct to breast cancer cryotherapy

Haifa Alkhalifa, Fatima Mohammed, Sebastien Taurin, Khaled Greish, Safa Taha, Salim Fredericks
Article Number: 458
Published online on: 08 April 2021

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Article

MicroRNA‑133a‑3p suppresses malignant behavior of non‑small cell lung cancer cells by negatively regulating ERBB2

Yanhui Xu, Lei Zhang, Lilong Xia, Xinhai Zhu
Article Number: 457
Published online on: 08 April 2021

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Article Open Access

Integrative analysis of the gastric cancer long non‑coding RNA‑associated competing endogenous RNA network

Yuyou Jiang, Xianqin Zhang, Li Rong, Yi Hou, Jing Song, Wanfeng Zhang, Min He, Yan Xie, Yue Li, Fangzhou Song
Article Number: 456
Published online on: 08 April 2021

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Article Open Access

lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma Corrigendum in /10.3892/ol.2021.12959

Hideharu Yamada, Masanobu Takahashi, Munenori Watanuki, Mika Watanabe, Sakura Hiraide, Ken Saijo, Keigo Komine, Chikashi Ishioka
Article Number: 455
Published online on: 08 April 2021

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Article Open Access

Prognosis of patients treated in a single neurosurgical reference centre for brain metastasis caused by dormant disseminated cells

Lorenzo Ferlini, Lorenzo Peluso, Valentina Lolli, Nicolas Gaspard, Florence Lefranc
Article Number: 454
Published online on: 08 April 2021

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Article Open Access

Daphnoretin induces reactive oxygen species‑mediated apoptosis in melanoma cells

Hui Wang, Xue Hu, Minjing Li, Zhaohai Pan, Defang Li, Qiusheng Zheng
Article Number: 453
Published online on: 08 April 2021

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Article

Ginsenoside Rg5 inhibits cancer cell migration by inhibiting the nuclear factor‑κB and erythropoietin‑producing hepatocellular receptor A2 signaling pathways

Leixin Song, Fan Yang, Zhengtao Wang, Li Yang, Yue Zhou
Article Number: 452
Published online on: 08 April 2021

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Review Open Access

Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs (Review)

Zhangming Chen, Jie Hu, Songcheng Ying, Aman Xu
Article Number: 451
Published online on: 08 April 2021

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Article Open Access

Excision repair cross‑complementing group 2 upregulation is a potential predictive biomarker for oral squamous cell carcinoma recurrence

Yen-Yun Wang, Pen-Tzu Fang, Chang-Wei Su, Yuk-Kwan Chen, Joh-Jong Huang, Ming-Yii Huang, Shyng-Shiou F. Yuan
Article Number: 450
Published online on: 07 April 2021

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Article Open Access

Impact of copy number variant and single nucleotide polymorphism of the programmed death‑ligand 1 gene, programmed death‑ligand 1 protein expression and therapy regimens on overall survival in a large group of Caucasian patients with non‑small cell lung carcinoma

Anna Grenda, Paweł Krawczyk, Tomasz Kucharczyk, Justyna Błach, Katarzyna Reszka, Izabela Chmielewska, Jarosław Buczkowski, Robert Kieszko, Jan Siwiec, Tomasz Kubiatowski, Aleksandra Bożyk, Kinga Krukowska, Bożena Jarosz, Iwona Paśnik, Juliusz Pankowski, Daria Świniuch, Katarzyna Stencel, Michał Gil, Kinga Lew, Rodryg Ramlau, Aleksandra Szczęsna, Sebastian Fidler, Andrzej Sieracki, Andrzej Każarnowicz, Piotr Serwatowski, Tomasz Grodzki, Janusz Milanowski
Article Number: 449
Published online on: 07 April 2021

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Article

Impact of EGFR and EGFR ligand expression on treatment response in patients with metastatic colorectal cancer

Fee Klupp, Malte Sass, Frank Bergmann, Elias Khajeh, Omid Ghamarnejad, Matthias Hassenpflug, Arianeb Mehrabi, Yakup Kulu
Article Number: 448
Published online on: 07 April 2021

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Article Open Access

Clinical value of lncRNA CCAT1 in serum extracellular vesicles as a potential biomarker for gastric cancer

Ke Xiao, Zhaogang Dong, Ding Wang, Min Liu, Juan Ding, Wendan Chen, Ziqi Shang, Congbo Yue, Yi Zhang
Article Number: 447
Published online on: 06 April 2021

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Article

Analysis of radiotherapy‑induced alteration of CD8+ T cells and PD‑L1 expression in patients with uterine cervical squamous cell carcinoma

Yasumasa Mori, Hiro Sato, Takuya Kumazawa, Tiara Bunga Mayang Permata, Yuya Yoshimoto, Kazutoshi Murata, Shin-Ei Noda, Takuya Kaminuma, Ken Ando, Takahiro Oike, Noriyuki Okonogi, Kohei Okada, Sangeeta Kakoti, Keiji Suzuki, Hayato Ikota, Hideaki Yokoo, Takashi Nakano, Tatsuya Ohno, Atsushi Shibata
Article Number: 446
Published online on: 06 April 2021

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Article Open Access

Stromal expression of cancer‑associated fibroblast‑related molecules, versican and lumican, is strongly associated with worse relapse‑free and overall survival times in patients with esophageal squamous cell carcinoma

Naoto Yamauchi, Yasuyuki Kanke, Katsuharu Saito, Hirokazu Okayama, Shoki Yamada, Shotaro Nakajima, Eisei Endo, Koji Kase, Leo Yamada, Hiroshi Nakano, Takuro Matsumoto, Hiroyuki Hanayama, Yohei Watanabe, Suguru Hayase, Motonobu Saito, Zenichiro Saze, Kosaku Mimura, Tomoyuki Momma, Shinji Oki, Yuko Hashimoto, Koji Kono
Article Number: 445
Published online on: 06 April 2021

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Article Open Access

Long non‑coding RNA HOTAIR promotes the progression of synovial sarcoma through microRNA‑126/stromal cell‑derived factor‑1 regulation

Qi Feng, Donglai Wang, Peng Guo, Zibo Zhang, Jiangang Feng
Article Number: 444
Published online on: 06 April 2021

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Article Open Access

Elevated XRCC5 expression level can promote temozolomide resistance and predict poor prognosis in glioblastoma

I-Neng Lee, Jen-Tsung Yang, Cheng Huang, Hsiu-Chen Huang, Yu-Ping Wu, Jui-Chieh Chen
Article Number: 443
Published online on: 06 April 2021

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Article Open Access

LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β‑catenin signaling pathway and epithelial‑mesenchymal transition

Min Xu, Bangyi Lin, Danni Zheng, Jialiang Wen, Wenjing Hu, Chunxue Li, Xianwei Zhang, Xiaohua Zhang, Jinmiao Qu
Article Number: 442
Published online on: 02 April 2021

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Article Open Access

Expression profiling of CPS1 in Correa's cascade and its association with gastric cancer prognosis

Xuqian Fang, Xiaoqiong Wu, Enfei Xiang, Fangxiu Luo, Qinqin Li, Qianchen Ma, Fei Yuan, Peizhan Chen
Article Number: 441
Published online on: 02 April 2021

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Article Open Access

DEK is highly expressed in breast cancer and is associated with malignant phenotype and progression

Mai-Qing Yang, Lin-Lin Bai, Zhao Wang, Lei Lei, Yi-Wen Zheng, Zhi-Han Li, Wen-Jing Huang, Chen-Chen Liu, Hong-Tao Xu
Article Number: 440
Published online on: 01 April 2021

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Review Open Access

Potential role of mitochondria in gastric cancer detection: Fission and glycolysis (Review)

Hang Yang, Yan Li, Bing Hu
Article Number: 439
Published online on: 01 April 2021

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Article Open Access

Recombinant protein TRAIL-Mu3 enhances the antitumor effects in pancreatic cancer cells by strengthening the apoptotic signaling pathway

Min Huang, Cheng Yi, Xian-Zhou Huang, Juan Yan, Li-Jia Wei, Wei-Ju Tang, Shou-Chun Chen, Ying Huang
Article Number: 438
Published online on: 01 April 2021

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Aquaporin 1 knockdown inhibits triple‑negative breast cancer cell proliferation and invasion in vitro and in vivo

Yinan Ji, Xiaoming Liao, Yi Jiang, Wei Wei, Huawei Yang
Article Number: 437
Published online on: 01 April 2021

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Ring finger 20/ring finger 40/WW domain‑containing adaptor with coiled‑coil complex interacts with p53 to regulate gene transcription in DNA damage response

Danni Meng, Kun Guo, Die Zhang, Cheng Zhao, Chuanwen Sun, Feng Zhang
Article Number: 436
Published online on: 01 April 2021

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β‑asarone suppresses HCT116 colon cancer cell proliferation and liver metastasis in part by activating the innate immune system

Min Chen, Yu-Wen Zhuang, Cun-En Wu, Hai-Yan Peng, Jun Qian, Jin-Yong Zhou
Article Number: 435
Published online on: 31 March 2021

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Epigenetic silencing of microRNA‑199a‑5p promotes the proliferation of non‑small cell lung cancer cells by increasing AKAP1 expression

Nengli Yang, Yafeng Liang, Tianqi Zhu, Yanxiao Long, Zhe Chen, Xuezheng Zhang, Liuming Jiang
Article Number: 434
Published online on: 31 March 2021

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Lentivirus‑mediated silencing of CNTN1 enhances gefitinib sensitivity by reversing epithelial‑mesenchymal transition in lung adenocarcinoma A549 cells

Chun-Sheng Hu, Jiu-Hong Huang, Dong-Lin Yang, Chuan Xu, Zhi-Gang Xu, Hong-Bo Tan, Zhong-Zhu Chen
Article Number: 433
Published online on: 31 March 2021

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Activation of GPER by E2 promotes proliferation, invasion and migration of breast cancer cells by regulating the miR‑124/CD151 pathway Retraction in /10.3892/ol.2025.15429

Huaicheng Yang, Congyu Wang, Heqiang Liao, Qi Wang
Article Number: 432
Published online on: 31 March 2021

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Siomycin A induces reactive oxygen species‑mediated cytotoxicity in ovarian cancer cells

Xiulan Shao, Fengying Zhang, Xiang Gao, Fengying Xu
Article Number: 431
Published online on: 31 March 2021

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Characterization and clinical evaluation of microsatellite instability and loss of heterozygosity in tumor‑related genes in gastric cancer

Xueyun Huo, Xiaoqin Xiao, Shuangyue Zhang, Xiaoyan Du, Changlong Li, Zhigang Bai, Zhenwen Chen
Article Number: 430
Published online on: 30 March 2021

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lncRNA LINC00473 promotes proliferation, migration, invasion and inhibition of apoptosis of non‑small cell lung cancer cells by acting as a sponge of miR‑497‑5p

Shao-Hua Xu, Yu-Hong Bo, Han-Chen Ma, Hua-Nan Zhang, Ming-Ju Shao
Article Number: 429
Published online on: 30 March 2021

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Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures

Birgit Lohberger, Dietmar Glaenzer, Nicole Eck, Bibiane Steinecker-Frohnwieser, Andreas Leithner, Beate Rinner, Sylvia Kerschbaum-Gruber, Dietmar Georg
Article Number: 428
Published online on: 30 March 2021

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Yuji Nitta, Tomoko Uchiyama, Akihiko Yoshizawa, Ryo Miyata, Masatsugu Hamaji, Hirotaka Kajihara, Masayuki Takeda
Article Number: 148
Published online on: 25 February 2026

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Gliosarcoma of the right cerebellar hemisphere and parahippocampal region: A case report and literature review

Fa Wu, Yulin Yang, Zaiqing Wang, Rui Jiang, Tingting Wu, Ting Yu, Peng Wang
Article Number: 147
Published online on: 25 February 2026

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Preliminary evidence for the integration of CNAs, CN‑LOH and mutational profiles into the prognostic stratification of elderly patients with NPM1‑mutated acute myeloid leukemia

Li Gao, Chunxia Zhang, Ming Gong, Zhengyi Cao, Chundi Liu, Sijie Wang, Zhenling Li
Article Number: 146
Published online on: 25 February 2026

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Pro‑tumourigenic effects of DCAF13 on the progression of colorectal cancer

Wenqi Zhang, Rongrong Zhang, Mengxuan Jia, Shuting Lan, Fangyuan Liu, Qin Jin, Liya Su, Gang Liu
Article Number: 145
Published online on: 25 February 2026

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Review Open Access

Histone deacetylases: Function in tumor development and therapeutic prospects (Review)

Runling Lin, Yu Zhang, Hong Li, Fan Liang
Article Number: 144
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Role of EphA2‑PI3K signaling in vasculogenic mimicry induced by cancer‑associated fibroblasts in gastric cancer cells

Hee Sung Kim, You Jin Won, Ju Hee Shim, Hyun Ji Kim, Byung Sik Kim, Hea Nam Hong
Article Number: 143
Published online on: 24 February 2026

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Case Report

Gastric cancer in pregnancy: A case report

Jianhua Niu, Yan Gao, Yu Sun, Huixia Yang
Article Number: 142
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro

Giovanni Vanni Frajese, Monica Benvenuto, Massimo Fantini, Elena Ambrosin, Pamela Sacchetti, Laura Masuelli, Maria Gabriella Giganti, Andrea Modesti, Roberto Bei
Article Number: 141
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2

Fenmei Zhou, Juan Chen, Hairong Wang
Article Number: 140
Published online on: 16 February 2026

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Case Report Open Access

Penile metastasis from prostate cancer with CDK12 mutation: A case report and literature review

Qi Xiang, Yanwu Wang, Bin Yao, Huiwen Tang, Qiang Dang
Article Number: 139
Published online on: 16 February 2026

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Case Report

Successful treatment with tepotinib followed by pembrolizumab in pulmonary pleomorphic carcinoma harbouring a MET exon 14 skipping mutation: A case report

Susumu Tanaka, Yu Saida, Yumi Ando, Jun Arinami, Ryo Yamazaki, Tomoya Wakabayashi, Hiroki Watanabe, Kohei Kushiro, Ryo Suzuki, Naohiro Yanagimura, Masashi Arita, Miyuki Sato, Tomohiro Tanaka, Koichiro Nozaki, Satoshi Watanabe, Shuhei Kondo, Hajime Umezu, Toshiaki Kikuchi
Article Number: 138
Published online on: 12 February 2026

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METTL5‑mediated m6A modification of 18S rRNA drives oral squamous cell carcinoma progression by enhancing CCND3 translation

Lianlian Liu, Surui Sheng, Xin Zheng, Shuojin Huang, Lu Wang, Dalong Shu, Leile Tang, Qianting He
Article Number: 137
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 136
Published online on: 12 February 2026

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Review Open Access

STOML2 promotes hepatocellular carcinoma cell proliferation, invasion and migration by activating the PI3K/AKT signaling pathway (Review)

Mengyan Li, Jianli Chen
Article Number: 135
Published online on: 11 February 2026

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Article

Fatty acid‑induced lipid accumulation promotes radiosensitization in Huh7 hepatocellular carcinoma cells

Haruto Tanaka, Yasushi Mariya, Satoru Monzen
Article Number: 134
Published online on: 11 February 2026

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Lactylation‑based machine algorithm combined with multi‑omics analysis to predict prognosis in cervical cancer

Ruyue Wang, Li Ning, Xiu Li, Yating Xu, Yu Si, Hongting Zhao, Qingling Ren
Article Number: 133
Published online on: 11 February 2026

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Potential treatment benefits of a GLP‑1R antagonist in combination with immune checkpoint inhibitors in colorectal cancer

Zengqin Zhan, Chuncha Zhan, Lianqiao Li, Dan Lan, Guya Meng, Fan Chen
Article Number: 132
Published online on: 10 February 2026

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Article

Effect of the hsa‑microRNA 200c‑3p/ZEB1 loop in epithelial‑mesenchymal transition of ovarian cancer cells

Merve Senturk, Ece Gumusoglu‑Acar, Samet Topuz, Tuba Gunel
Article Number: 131
Published online on: 10 February 2026

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Inhibition of IRE1α kinase increases ferroptosis resistance in triple‑negative breast cancer cells

Shuo Xu, Si-Qi Yang
Article Number: 130
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS

Yi Xiao, Taoran Deng, Changliang Su, Zhen Shang
Article Number: 129
Published online on: 09 February 2026

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Case Report Open Access

Metastatic breast cancer in primary lung cancer with compound EGFR mutations: A case report

Tianyao Yang, Yifan Xu, Xi Lin, Guodong Chen, Fangfang Wang
Article Number: 128
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen, Jia Li
Article Number: 126
Published online on: 03 February 2026

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Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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