Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
July-2021 Volume 22 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
July-2021 Volume 22 Issue 1

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer

  • Authors:
    • Zhe Chen
    • Jing Li
    • Qianqian Cui
    • Fuyuan Li
    • Gaiying Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China, CT Room, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China
    Copyright: © Chen et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 550
    |
    Published online on: May 24, 2021
       https://doi.org/10.3892/ol.2021.12811
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Breast cancer is the leading cause of tumor‑associated death among women worldwide, and new therapeutic strategies are required to improve the post‑surgery prognosis and quality of life of patients. Radiofrequency ablation (RFA) is a less invasive approach compared with traditional surgical resection to treat malignancies, and the combination of RFA and chemotherapeutic agents, including formosanin C (FC), can synergistically improve the curative effects against breast carcinoma. However, the detailed mechanisms remain unclear. In the present study, nude mice were used to identify the influence of FC on the therapeutic efficacy of RFA for breast cancer. Flow cytometry was performed to demonstrate the proportional alteration of CD8+ and CD45+ T cells with different biomarkers, including CD107a, IFNγ and TNFα. It was demonstrated that FC enhanced the therapeutic efficacy of RFA in breast cancer, while RFA combined with FC improved the proportion of IFNγ+ and TNFα+ CD8+ T cells and CD107a+ CD8+ T cells in tumor‑infiltrating lymphocytes, thus increasing the immune responses caused by surgery and chemotherapy. The present study indicated that FC may promote the curative efficacy of ultrasound‑guided RFA against breast tumor by regulating adaptive immune responses.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Webster S, Lawn S, Chan R and Koczwara B: The role of comorbidity assessment in guiding treatment decision-making for women with early breast cancer: A systematic literature review. Support Care Cancer. 28:1041–1050. 2020. View Article : Google Scholar : PubMed/NCBI

2 

Wanchai A and Armer JM: A systematic review association of reflexology in managing symptoms and side effects of breast cancer treatment. Complement Ther Clin Pract. 38:1010742020. View Article : Google Scholar : PubMed/NCBI

3 

Wang Y and Chen Z: Mutation detection and molecular targeted tumor therapies. STEMedicine. 1:e112020. View Article : Google Scholar

4 

Sun Y, Ji S, Ji H, Liu L and Li C: Clinical efficacy analysis of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) in primary liver cancer and recurrent liver cancer. J BUON. 24:1402–1407. 2019.PubMed/NCBI

5 

Zimmermann M, Pedersoli F, Schulze-Hagen M, Lurje G, Isfort P, Kuhl C and Bruners P: Salvage RFA in patients with intrahepatic recurrence after major hepatic surgery for colorectal cancer liver metastases: Mid-term outcome. Eur Radiol. 30:1221–1227. 2020. View Article : Google Scholar : PubMed/NCBI

6 

Veltri A, Gazzera C, Barrera M, Busso M, Solitro F, Filippini C and Garetto I: Radiofrequency thermal ablation (RFA) of hepatic metastases (METS) from breast cancer (BC): An adjunctive tool in the multimodal treatment of advanced disease. Radiol Med. 119:327–333. 2014. View Article : Google Scholar : PubMed/NCBI

7 

Carrafiello G, Fontana F, Cotta E, Petullà M, Brunese L, Mangini M and Fugazzola C: Ultrasound-guided thermal radiofrequency ablation (RFA) as an adjunct to systemic chemotherapy for breast cancer liver metastases. Radiol Med. 116:1059–1066. 2011.(In Italian). View Article : Google Scholar : PubMed/NCBI

8 

Ueki A, Okuma T, Hamamoto S, Kageyama K, Murai K and Miki Y: Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model. BMC Res Notes. 11:2512018. View Article : Google Scholar : PubMed/NCBI

9 

Armstrong DK, Bundy B, Wenzel L, Huang HQ, Baergen R, Lele S, Copeland LJ, Walker JL and Burger RA; Gynecologic Oncology Group, : Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med. 354:34–43. 2006. View Article : Google Scholar : PubMed/NCBI

10 

Wu RT, Chiang HC, Fu WC, Chien KY, Chung YM and Horng LY: Formosanin-C, an immunomodulator with antitumor activity. Int J Immunopharmacol. 12:777–786. 1990. View Article : Google Scholar : PubMed/NCBI

11 

Li Y, Man S, Li J, Chai H, Fan W, Liu Z and Gao W: The antitumor effect of formosanin C on HepG2 cell as revealed by 1H-NMR based metabolic profiling. Chem Biol Interact. 220:193–199. 2014. View Article : Google Scholar : PubMed/NCBI

12 

Chiang HC, Wang JJ and Wu RT: Immunomodulating effects of the hydrolysis products of formosanin C and beta-ecdysone from Paris formosana Hayata. Anticancer Res. 12:1475–1478. 1992.PubMed/NCBI

13 

Man S, Gao W, Zhang Y, Liu Z, Yan L, Huang L and Liu C: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. Cancer Biol Ther. 11:592–598. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Savas P and Loi S: Metastatic breast cancer: TIL it is too late. Clin Cancer Res. 26:526–528. 2020. View Article : Google Scholar : PubMed/NCBI

15 

Harao M, Forget MA, Roszik J, Gao H, Babiera GV, Krishnamurthy S, Chacon JA, Li S, Mittendorf EA, DeSnyder SM, et al: 4-1BB-Enhanced Expansion of CD8+ TIL from triple-negative breast cancer unveils mutation-specific CD8+ T cells. Cancer Immunol Res. 5:439–445. 2017. View Article : Google Scholar : PubMed/NCBI

16 

Xiao X, Yang M, Xiao J, Zou J, Huang Q, Yang K, Zhang B, Yang F, Liu S, Wang H and Bai P: Paris Saponin II suppresses the growth of human ovarian cancer xenografts via modulating VEGF-mediated angiogenesis and tumor cell migration. Cancer Chemother Pharmacol. 73:807–818. 2014. View Article : Google Scholar : PubMed/NCBI

17 

Lee JC, Su CL, Chen LL and Won SJ: Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential. Cancer Sci. 100:503–513. 2009. View Article : Google Scholar : PubMed/NCBI

18 

Dwerryhouse SJ, Soon Lee C, King J, Magarey C, Schwartz P and Morris DL: Cimetidine does not influence TIL in breast cancer. Int J Surg Investig. 1:191–194. 1999.PubMed/NCBI

19 

Shen J, Xiao Z, Zhao Q, Li M, Wu X, Zhang L, Hu W and Cho CH: Anti-cancer therapy with TNFα and IFNγ: A comprehensive review. Cell Prolif. 51:e124412018. View Article : Google Scholar : PubMed/NCBI

20 

Alter G, Malenfant JM and Altfeld M: CD107a as a functional marker for the identification of natural killer cell activity. J Immunol Methods. 294:15–22. 2004. View Article : Google Scholar : PubMed/NCBI

21 

Iacoviello L, Bonaccio M, de Gaetano G and Donati MB: Epidemiology of breast cancer, a paradigm of the ‘common soil’ hypothesis. Semin Cancer Biol. Feb 20–2020.(Epub ahead of print). PubMed/NCBI

22 

Malmgren JA, Calip GS, Atwood MK, Mayer M and Kaplan HG: Metastatic breast cancer survival improvement restricted by regional disparity: Surveillance, epidemiology, and end results and institutional analysis: 1990 to 2011. Cancer. 126:390–399. 2020. View Article : Google Scholar : PubMed/NCBI

23 

Yin M, Verschraegen C, Vincent VH, Patel SM, George T and Truica CI: Impact of lack of surgery on outcomes in elderly women with nonmetastatic breast cancer-A surveillance, epidemiology, and end results 18 population based study. Medicine (Baltimore). 99:e187452020. View Article : Google Scholar : PubMed/NCBI

24 

Lee J and Lee MG: Effects of exercise interventions on breast cancer patients during adjuvant therapy: A systematic review and meta-analysis of randomized controlled trials. Cancer Nurs. 43:115–125. 2020. View Article : Google Scholar : PubMed/NCBI

25 

Banys-Paluchowski M, Gruber IV, Hartkopf A, Paluchowski P, Krawczyk N, Marx M, Brucker S and Hahn M: Axillary ultrasound for prediction of response to neoadjuvant therapy in the context of surgical strategies to axillary dissection in primary breast cancer: A systematic review of the current literature. Arch Gynecol Obstet. 301:341–353. 2020. View Article : Google Scholar : PubMed/NCBI

26 

Napoletano C, Taurino F, Biffoni M, De Majo A, Coscarella G, Bellati F, Rahimi H, Pauselli S, Pellicciotta I, Burchell JM, et al: RFA strongly modulates the immune system and anti-tumor immune responses in metastatic liver patients. Int J Oncol. 32:481–490. 2008.PubMed/NCBI

27 

Singh S, Bhowmik A and Repaka R: Thermal analysis of induced damage to the healthy cell during RFA of breast tumor. J Therm Biol. 58:80–90. 2016. View Article : Google Scholar : PubMed/NCBI

28 

Sommer CM, Pallwein-Prettner L, Vollherbst DF, Seidel R, Rieder C, Radeleff BA, Kauczor HU, Wacker F, Richter GM, Bücker A, et al: Transarterial embolization (TAE) as add-on to percutaneous radiofrequency ablation (RFA) for the treatment of renal tumors: Review of the literature, overview of state-of-the-art embolization materials and further perspective of advanced image-guided tumor ablation. Eur J Radiol. 86:143–162. 2017. View Article : Google Scholar : PubMed/NCBI

29 

Xiao YB, Zhang B and Wu YL: Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: A systematic review and meta-analysis. J Zhejiang Univ Sci B. 19:829–843. 2018. View Article : Google Scholar : PubMed/NCBI

30 

Sofocleous CT, Nascimento RG, Petrovic LM, Klimstra DS, Gonen M, Brown KT, Brody LA, Covey AM, Thornton RH, Fong Y, et al: Histopathologic and immunohistochemical features of tissue adherent to multitined electrodes after RF ablation of liver malignancies can help predict local tumor progression: Initial results. Radiology. 249:364–374. 2008. View Article : Google Scholar : PubMed/NCBI

31 

Ni JY, Liu SS, Xu LF, Sun HL and Chen YT: Meta-analysis of radiofrequency ablation in combination with transarterial chemoembolization for hepatocellular carcinoma. World J Gastroenterol. 19:3872–3882. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Guo W, He X, Li Z and Li Y: Combination of Transarterial Chemoembolization (TACE) and Radiofrequency Ablation (RFA) vs. Surgical Resection (SR) on survival outcome of early hepatocellular carcinoma: A meta-analysis. Hepatogastroenterology. 62:710–714. 2015.PubMed/NCBI

33 

Ahmed M and Goldberg SN: Combination radiofrequency thermal ablation and adjuvant IV liposomal doxorubicin increases tissue coagulation and intratumoural drug accumulation. Int J Hyperthermia. 20:781–802. 2004. View Article : Google Scholar : PubMed/NCBI

34 

Wu H, Fan ZP, Jiang AN, Di XS, He B, Wang S, Goldberg SN, Ahmed M, Zhang Q and Yang W: Combination of intratumoural micellar paclitaxel with radiofrequency ablation: Efficacy and toxicity in rodents. Eur Radiol. 29:6202–6210. 2019. View Article : Google Scholar : PubMed/NCBI

35 

Liu J, Man S, Liu Z, Ma L and Gao W: A synergistic antitumor effect of polyphyllin I and formosanin C on hepatocarcinoma cells. Bioorg Med Chem Lett. 26:4970–4975. 2016. View Article : Google Scholar : PubMed/NCBI

36 

He QF, Xu Y, Li J, Huang ZM, Li XH and Wang X: CD8+ T-cell exhaustion in cancer: Mechanisms and new area for cancer immunotherapy. Brief Funct Genomics. 18:99–106. 2019. View Article : Google Scholar : PubMed/NCBI

37 

Hammerl D, Massink MPG, Smid M, van Deurzen CHM, Meijers-Heijboer HEJ, Waisfisz Q, Debets R and Martens JWM: Clonality, antigen recognition, and suppression of CD8(+) T cells differentially affect prognosis of breast cancer subtypes. Clin Cancer Res. 26:505–517. 2020. View Article : Google Scholar : PubMed/NCBI

38 

Wang MQ, Hou M, Lin DP and Wang YG: Proportion and role of CD45+ erythroid progenitor cells in patients with tongue cancer metastasis. Zhonghua Kou Qiang Yi Xue Za Zhi. 54:445–449. 2019.(In Chinese). PubMed/NCBI

39 

Kitahara T, Haraguchi N, Takahashi H, Nishimura J, Hata T, Takemasa I, Mizushima T, Yamamoto H, Doki Y and Mori M: Identification and characterization of CD107a as a marker of low reactive oxygen species in chemoresistant cells in colorectal cancer. Ann Surg Oncol. 24:1110–1119. 2017. View Article : Google Scholar : PubMed/NCBI

40 

Kittaneh M, Badve S, Caldera H, Coleman R, Goetz MP, Mahtani R, Mamounas E, Kalinsky K, Lower E, Pegram M, et al: Case-based review and clinical guidance on the use of genomic assays for early-stage breast cancer: Breast Cancer therapy expert group (BCTEG). Clin Breast Cancer. 20:183–193. 2020. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Chen Z, Li J, Cui Q, Li F and Zhang G: Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer. Oncol Lett 22: 550, 2021.
APA
Chen, Z., Li, J., Cui, Q., Li, F., & Zhang, G. (2021). Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer. Oncology Letters, 22, 550. https://doi.org/10.3892/ol.2021.12811
MLA
Chen, Z., Li, J., Cui, Q., Li, F., Zhang, G."Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer". Oncology Letters 22.1 (2021): 550.
Chicago
Chen, Z., Li, J., Cui, Q., Li, F., Zhang, G."Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer". Oncology Letters 22, no. 1 (2021): 550. https://doi.org/10.3892/ol.2021.12811
Copy and paste a formatted citation
x
Spandidos Publications style
Chen Z, Li J, Cui Q, Li F and Zhang G: Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer. Oncol Lett 22: 550, 2021.
APA
Chen, Z., Li, J., Cui, Q., Li, F., & Zhang, G. (2021). Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer. Oncology Letters, 22, 550. https://doi.org/10.3892/ol.2021.12811
MLA
Chen, Z., Li, J., Cui, Q., Li, F., Zhang, G."Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer". Oncology Letters 22.1 (2021): 550.
Chicago
Chen, Z., Li, J., Cui, Q., Li, F., Zhang, G."Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer". Oncology Letters 22, no. 1 (2021): 550. https://doi.org/10.3892/ol.2021.12811
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team