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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2021 Volume 22 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tenascin‑C promotes epithelial‑to‑mesenchymal transition and the mTOR signaling pathway in nasopharyngeal carcinoma

Xiang Cheng, Fen Li, Zezhang Tao
Article Number: 570
Published online on: 29 May 2021

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Article Open Access

Dacomitinib improves chemosensitivity of cisplatin‑resistant human ovarian cancer cells

Lei Xu, Ying Xu, Jianbing Zheng, Yun Zhao, Hongcai Wang, Yushu Qi
Article Number: 569
Published online on: 29 May 2021

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Article Open Access

Characterization of the small RNA transcriptomes of cell protrusions and cell bodies of highly metastatic hepatocellular carcinoma cells via RNA sequencing

Wenpin Cai, Jingzhang Ji, Biting Wu, Kaixuan Hao, Ping Ren, Yu Jin, Lihong Yang, Qingchao Tong, Zhifa Shen
Article Number: 568
Published online on: 29 May 2021

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Article Open Access

lncRNA IUR upregulates miR‑34a to inhibit pancreatic adenocarcinoma cell migratory and invasive abilities

Ren Li, Jian Zhang, Shiyang Ma, Gang Zhao, Jun Li, Jiangwei Li, Xiaoyi Wang, Bo Hui
Article Number: 567
Published online on: 29 May 2021

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Review Open Access

Effect of melanoma stem cells on melanoma metastasis (Review)

Qiliang Yin, Xiumin Shi, Shijie Lan, Haofan Jin, Di Wu
Article Number: 566
Published online on: 29 May 2021

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Article Open Access

lncRNA SNHG7 promotes cell proliferation in glioma by acting as a competing endogenous RNA and sponging miR‑138‑5p to regulate EZH2 expression

Yanyao Deng, Liuyang Cheng, Zhicheng Lv, Hongwei Zhu, Xiangrui Meng
Article Number: 565
Published online on: 29 May 2021

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Review Open Access

LZTR1: A promising adaptor of the CUL3 family (Review)

Hui Zhang, Xinyi Cao, Jian Wang, Qian Li, Yiting Zhao, Xiaofeng Jin
Article Number: 564
Published online on: 29 May 2021

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Article Open Access

circMTO1 sponges microRNA‑219a‑5p to enhance gallbladder cancer progression via the TGF‑β/Smad and EGFR pathways

Pingfan Wang, Chenggang Zhou, Donghai Li, Dongsheng Zhang, Long Wei, Ying Deng
Article Number: 563
Published online on: 27 May 2021

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Article Open Access

Triptolide inhibits matrix metalloproteinase-9 expression and invasion of breast cancer cells through the inhibition of NF-κB and AP-1 signaling pathways

On-Yu Hong, Hye-Yeon Jang, Kwang-Hyun Park, Young-Ju Jeong, Jong-Suk Kim, Hee Suk Chae
Article Number: 562
Published online on: 27 May 2021

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Article Open Access

Clinical value of color Doppler ultrasound combined with serum tumor markers for the diagnosis of medullary thyroid carcinoma

Xue Yang, Jinjuan Xu, Jilan Sun, Lizhi Yin, Rui Guo, Zhimei Yan
Article Number: 561
Published online on: 27 May 2021

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Article Open Access

MicroRNA expression profiling involved in doxorubicin‑induced cardiotoxicity using high‑throughput deep‑sequencing analysis

Ying Chen, Yingjie Xu, Zhoufeng Deng, Yin Wang, Ying Zheng, Weihua Jiang, Li Jiang
Article Number: 560
Published online on: 26 May 2021

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Case Report Open Access

Whole genome, exon mutation and transcriptomic profiling of acute myeloid leukemia: A case report

Si-Han Lai, Ye-Cheng Li, Shan Zhang, Rui Deng, Yan Deng, Fang-Yi Fan
Article Number: 559
Published online on: 25 May 2021

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Article Open Access

Enhanced G1 arrest and apoptosis via MDM4/MDM2 double knockdown and MEK inhibition in wild‑type TP53 colon and gastric cancer cells with aberrant KRAS signaling

Xiaoxuan Wang, Yoshiyuki Yamamoto, Mamiko Imanishi, Xiaochen Zhang, Masashi Sato, Akinori Sugaya, Mitsuaki Hirose, Shinji Endo, Yukikazu Natori, Toshikazu Moriwaki, Kenji Yamato, Ichinosuke Hyodo
Article Number: 558
Published online on: 25 May 2021

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Article Open Access

Upregulation of LINC00659 expression predicts a poor prognosis and promotes migration and invasion of gastric cancer cells Corrigendum in /10.3892/ol.2023.13785

Pihai Gong, Ying Xu, Min Liu, Xiaohui Shen, Yuhang Mao, Yiping Li, Kun Zhang, Shenling Yu, Hong Fan
Article Number: 557
Published online on: 24 May 2021

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Article Open Access

Integrin α5 promotes migration and invasion through the FAK/STAT3/AKT signaling pathway in icotinib‑resistant non‑small cell lung cancer cells

Yang Yang, Yizhe Wang, Xiaofang Che, Kezuo Hou, Jie Wu, Chunlei Zheng, Yang Cheng, Yunpeng Liu, Xuejun Hu, Jingdong Zhang
Article Number: 556
Published online on: 24 May 2021

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Article Open Access

Challenges in bioinformatics approaches to tumor mutation burden analysis

Francesca Fenizia, Raffaella Pasquale, Riziero Esposito Abate, Matilde Lambiase, Cristin Roma, Francesca Bergantino, Ruchi Chaudhury, Fiona Hyland, Christopher Allen, Nicola Normanno
Article Number: 555
Published online on: 24 May 2021

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Article Open Access

Effects of transarterial chemoembolization on the immunological function of patients with hepatocellular carcinoma

Jingjing Guo, Saixia Wang, Yujing Han, Zhongyuan Jia, Runchao Wang
Article Number: 554
Published online on: 24 May 2021

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Article Open Access

PD‑L1 expression and immune cells in anaplastic carcinoma and poorly differentiated carcinoma of the human thyroid gland: A retrospective study

Soledad Cameselle‑García, Sámer Abdulkader‑Sande, María Sánchez‑Ares, Gemma Rodríguez‑Carnero, Jesús Garcia‑Gómez, Francisco Gude‑Sampedro, Ihab Abdulkader‑Nallib, José Manuel Cameselle‑Teijeiro
Article Number: 553
Published online on: 24 May 2021

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Article Open Access

Apatinib plus ifosfamide and etoposide for relapsed or refractory osteosarcoma: A retrospective study in two centres

Lu Xie, Jie Xu, Xin Sun, Xiaowei Li, Kuisheng Liu, Xin Liang, Zuli Zhou, Hongqing Zhuang, Kunkun Sun, Yiming Wu, Jin Gu, Wei Guo
Article Number: 552
Published online on: 24 May 2021

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Article Open Access

Changes in SLIT2 expression are associated with the migration of human ovarian clear cell carcinoma cells

Cuei-Jyuan Lin, Way-Ren Huang, Chia-Zhen Wu, Ruo-Chia Tseng
Article Number: 551
Published online on: 24 May 2021

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Article Open Access

Formosanin C promotes the curative efficacy of ultrasound‑guided radiofrequency ablation in a mouse model of breast cancer

Zhe Chen, Jing Li, Qianqian Cui, Fuyuan Li, Gaiying Zhang
Article Number: 550
Published online on: 24 May 2021

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Article Open Access

MIF promoter polymorphism increases peripheral blood expression levels, contributing to increased susceptibility and poor prognosis in hepatocellular carcinoma

Lifeng Qin, Jinmei Qin, Xiaoping Lv, Caiqiao Yin, Qian'e Zhang, Jiqiao Zhang
Article Number: 549
Published online on: 24 May 2021

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Review Open Access

Cytochrome P450: Implications for human breast cancer (Review)

Bin Luo, Dandan Yan, Honglin Yan, Jingping Yuan
Article Number: 548
Published online on: 24 May 2021

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Article Open Access

Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late‑stage breast cancer

Hitomi Motomura, Ayaka Ozaki, Shoma Tamori, Chotaro Onaga, Yuka Nozaki, Yuko Waki, Ryoko Takasawa, Kazumi Yoshizawa, Yasunari Mano, Tsugumichi Sato, Kazunori Sasaki, Hitoshi Ishiguro, Yohei Miyagi, Yoji Nagashima, Kouji Yamamoto, Keiko Sato, Takehisa Hanawa, Sei-Ichi Tanuma, Shigeo Ohno, Kazunori Akimoto
Article Number: 547
Published online on: 24 May 2021

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Article Open Access

Six-transmembrane epithelial antigen of the prostate 1 accelerates cell proliferation by targeting c-Myc in liver cancer cells

Kazutaka Iijima, Hajime Nakamura, Kohichi Takada, Naotaka Hayasaka, Tomohiro Kubo, Yui Umeyama, Satoshi Iyama, Koji Miyanishi, Masayoshi Kobune, Junji Kato
Article Number: 546
Published online on: 24 May 2021

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Retraction Open Access

[Retracted] miR‑429 promotes the proliferation of non‑small cell lung cancer cells via targeting DLC‑1

Peng Xiao, Wenliang Liu, Hui Zhou
Article Number: 545
Published online on: 24 May 2021

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Article Open Access

Long non‑coding RNA CASC9/microRNA‑590‑3p axis participates in lutein‑mediated suppression of breast cancer cell proliferation

Yuxia Zhang, Jingzhi Chang, Weiwei Jiang, Xin Ye, Shanfeng Zhang
Article Number: 544
Published online on: 20 May 2021

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Article Open Access

Immune-related gene expression signatures in colorectal cancer

Zhenqing Sun, Wei Xia, Yali Lyu, Yanan Song, Min Wang, Ruirui Zhang, Guode Sui, Zhenlu Li, Li Song, Changliang Wu, Choong-Chin Liew, Lei Yu, Guang Cheng, Changming Cheng
Article Number: 543
Published online on: 20 May 2021

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Article Open Access

Generation of TIM3 inhibitory single‑domain antibodies to boost the antitumor activity of chimeric antigen receptor T cells

Liu Yang, Xin Chen, Qian Wang, Yuankui Zhu, Changfa Wu, Xuqian  Ma, Dianbao Zuo, Huixia He, Le Huang, Jingwen Li, Chunjiao  Xia, Sheng Hu, Xiaoqing Yang, Mingqian Feng
Article Number: 542
Published online on: 20 May 2021

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Article Open Access

Long non‑coding RNA LINC01018 inhibits the progression of acute myeloid leukemia by targeting miR‑499a‑5p to regulate PDCD4

Hong Zhou, Pengfei Shi, Xiaofeng Jia, Qianfu Xue
Article Number: 541
Published online on: 20 May 2021

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Article Open Access

Immune‑related genes and gene sets for predicting the response to anti‑programmed death 1 therapy in patients with primary or metastatic non‑small cell lung cancer

Bolin Chen, Min Yang, Kang Li, Jia Li, Li Xu, Fang Xu, Yan Xu, Dandan Ren, Jiao Zhang, Liyu Liu
Article Number: 540
Published online on: 19 May 2021

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Article Open Access

MicroRNA‑186‑3p attenuates tumorigenesis of cervical cancer by targeting MCM2

Xiurong Lu, Xiao Song, Xiaohui Hao, Xiaoyu Liu, Xianyu Zhang, Na Yuan, Huan Ma, Zhilin Zhang
Article Number: 539
Published online on: 19 May 2021

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Article Open Access

Novel prognostic implications of YTH domain family 2 in resected hepatocellular carcinoma

Nobuhiko Nakagawa, Fuminori Sonohara, Katsuhito Tanaka, Yuki Sunagawa, Yoshikuni Inokawa, Hideki Takami, Masamichi Hayashi, Suguru Yamada, Mitsuro Kanda, Chie Tanaka, Goro Nakayama, Masahiko Koike, Yasuhiro Kodera
Article Number: 538
Published online on: 19 May 2021

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Article Open Access

PDGF‑BB regulates the transformation of fibroblasts into cancer‑associated fibroblasts via the lncRNA LURAP1L‑AS1/LURAP1L/IKK/IκB/NF‑κB signaling pathway

Xiaobin Ren, Lei Li, Jianhua Wu, Ken Lin, Yongwen He, Li Bian
Article Number: 537
Published online on: 19 May 2021

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Article Open Access

MMP12 is a potential therapeutic target for Adamantinomatous craniopharyngioma: Conclusions from bioinformatics analysis and in vitro experiments

Minde Li, Lin Zhou, Shaoyang Li, Linchun Fang, Le Yang, Xiao Wu, Chenxing Yang, Youyuan Bao, Sihai Lan, Zhigao Tong, Suyue Zheng, Bin Tang, Erming Zeng, Shenhao Xie, Cheng Chen, Tao Hong
Article Number: 536
Published online on: 19 May 2021

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Article Open Access

HLA complex group 11 is involved in colorectal carcinoma cisplatin resistance via the miR‑214‑5p/SOX4 axis

Jianping Xie, Jiaping Zhu, Jie Pang, Yaping Ma
Article Number: 535
Published online on: 19 May 2021

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Article Open Access

PLEK2 promotes osteosarcoma tumorigenesis and metastasis by activating the PI3K/AKT signaling pathway

Yang Liu, Siting Yang, Feng Wang, Zheng Zhou, Wenjing Xu, Jingjing Xie, Linhui Qiao, Yanglin Gu
Article Number: 534
Published online on: 18 May 2021

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Article Open Access

Cyclooxygenase‑2 expression is associated with chemoresistance through cancer stemness property in hypopharyngeal carcinoma

Shin Saito, Hiroyuki Ozawa, Yorihisa Imanishi, Mariko Sekimizu, Yoshihiro Watanabe, Fumihiro Ito, Yuichi Ikari, Nana Nakahara, Kaori Kameyama, Kaoru Ogawa
Article Number: 533
Published online on: 17 May 2021

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Article Open Access

miR‑590‑5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines

Sixing Chen, Yu Chen, Yao Wen, Wanwan Cai, Ping Zhu, Wuzhou Yuan, Yongqing Li, Xiongwei Fan, Yongqi Wan, Fang Li, Jian Zhuang, Zhigang Jiang, Xiushan Wu, Yuequn Wang
Article Number: 532
Published online on: 17 May 2021

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Article Open Access

MCTS1 promotes the development of lung adenocarcinoma by regulating E2F1 expression

Cun Gao, Rui Dong, Yongmeng Li, Jinghui Liang, Hui Tian
Article Number: 531
Published online on: 17 May 2021

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Review Open Access

Cell fusion in cancer hallmarks: Current research status and future indications (Review)

Hao-Fei Wang, Wei Xiang, Bing-Zhou Xue, Yi-Hao Wang, Dong-Ye  Yi, Xiao-Bing Jiang, Hong-Yang Zhao, Peng Fu
Article Number: 530
Published online on: 16 May 2021

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Article Open Access

Long non‑coding RNA SLC25A25‑AS1 exhibits oncogenic roles in non‑small cell lung cancer by regulating the microRNA‑195‑5p/ITGA2 axis Retraction in /10.3892/ol.2024.14608

Jinqin Chen, Chengpeng Gao, Wei Zhu
Article Number: 529
Published online on: 16 May 2021

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Article Open Access

Human papillomavirus‑16 infection and p16 expression in oral squamous cell carcinoma

Norihiko Tokuzen, Koh-Ichi Nakashiro, Shin Tojo, Hiroyuki Goda, Nobuyuki Kuribayashi, Daisuke Uchida
Article Number: 528
Published online on: 14 May 2021

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Article Open Access

Downregulation of GLUT3 impairs STYK1/NOK‑mediated metabolic reprogramming and proliferation in NIH‑3T3 cells

Weiye Shi, Yu Fu, Yingze Wang
Article Number: 527
Published online on: 14 May 2021

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Article Open Access

Prognostic and immunological roles of Fc fragment of IgG binding protein in colorectal cancer

Qunchuan Zhuang, Aling Shen, Liya Liu, Meizhu Wu, Zhiqing Shen, Huixin Liu, Ying Cheng, Xiaoying Lin, Xiangyan Wu, Wei Lin, Jiapeng Li, Yuying Han, Xiaoping Chen, Qi Chen, Jun Peng
Article Number: 526
Published online on: 13 May 2021

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Article Open Access

Clinicopathological characteristics of pancreatic ductal adenocarcinoma with invasive micropapillary carcinoma component with emphasis on the usefulness of PKCζ immunostaining for detection of reverse polarity

Hironori Ryota, Mitsuaki Ishida, Yusuke Ebisu, Hiroaki Yanagimoto, Tomohisa Yamamoto, Hisashi Kosaka, Satoshi Hirooka, So Yamaki, Masaya Kotsuka, Yoichi Matsui, Koji Tsuta, Sohei Satoi
Article Number: 525
Published online on: 13 May 2021

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Article Open Access

Dynamin 3 overexpression suppresses the proliferation, migration and invasion of cervical cancer cells

Jing Fa
Article Number: 524
Published online on: 12 May 2021

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Article

Antitumor effects of Andrographis via ferroptosis‑associated genes in gastric cancer

Ruiya Ma, Tadanobu Shimura, Chengzeng Yin, Yoshinaga Okugawa, Takahito Kitajima, Yuhki Koike, Yoshiki Okita, Masaki Ohi, Keiichi Uchida, Ajay Goel, Li Yao, Xueming Zhang, Yuji Toiyama
Article Number: 523
Published online on: 12 May 2021

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Article Open Access

Novel circulating tumor cell‑detection chip combining conventional podoplanin and EGFR antibodies for all histological malignant pleural mesothelioma

Masatoshi Kanayama, Rintaro Oyama, Masataka Mori, Akihiro Taira, Shinji Shinohara, Taiji Kuwata, Masaru Takenaka, Kazue Yoneda, Koji Kuroda, Takashi Ohnaga, Yukinari Kato, Fumihiro Tanaka
Article Number: 522
Published online on: 11 May 2021

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Article Open Access

GFI‑1 overexpression promotes cell proliferation and apoptosis resistance in mycosis fungoides by repressing Bax and P21

Xiaoguang Gu, Yimeng Wang, Chunlei Zhang, Yongsheng Liu
Article Number: 521
Published online on: 11 May 2021

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Article Open Access

Potential of the cell‑free blood‑based biomarker uroplakin 2 RNA to detect recurrence after surgical resection of lung adenocarcinoma

Ji Zhu, Qijue Lu, Bin Li, Huafei Li, Cong Wu, Chunguang Li, Hai Jin
Article Number: 520
Published online on: 10 May 2021

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Correction Open Access

[Corrigendum] The expression of Wnt‑1 inducible signaling pathway protein‑2 in astrocytoma: Correlation between pathological grade and clinical outcome

Gelei Xiao, Zhi Tang, Xianrui Yuan, Jian Yuan, Jie  Zhao, Zhiping Zhang, Zhengwen He, Jingping  Liu
Article Number: 519
Published online on: 10 May 2021

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Article Open Access

Effect of trachea stiffness on tumor distribution in papillary thyroid microcarcinoma

Hua Zhang, Taiyang Li, Xilong Du, Qihang Li, Bo Huo, Rui Jin, Ping Li
Article Number: 518
Published online on: 07 May 2021

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Article Open Access

Downregulation of SOX9 suppresses breast cancer cell proliferation and migration by regulating apoptosis and cell cycle arrest

Yu-Feng Wang, Hui-Feng Dang, Xu Luo, Qian-Qian Wang, Chen Gao, Ying-Xia Tian
Article Number: 517
Published online on: 06 May 2021

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Article Open Access

Regulatory effect of microRNA‑223‑3p on breast cancer cell processes via the Hippo/Yap signaling pathway

Tonghua Du, Dan Wang, Xiaoyu Wan, Jingwei Xu, Qi Xiao, Bin Liu
Article Number: 516
Published online on: 06 May 2021

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Article

MicroRNA‑383‑5p predicts favorable prognosis and inhibits the progression of diffuse large B‑cell lymphoma

Li-Yan Chen, Bi-Qing Han, Xiao-Min Zhang, Xing-Bao Yu, Dan-Dan Yao, Li-Qian Yu
Article Number: 515
Published online on: 06 May 2021

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Review Open Access

Nasopharyngeal carcinoma among the Bidayuh of Sarawak, Malaysia: history and risk factors (Review)

Reagan Entigu Linton, Maelinda Daker, Alan Soo‑Beng Khoo, Diana Chung Yiing Choo, Mignon Viljoen, Paul M. Neilsen
Article Number: 514
Published online on: 06 May 2021

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Article

Differentiation‑related zinc finger protein 750 suppresses cell growth in esophageal squamous cell carcinoma

Sheyne Sta Ana Choi, Josephine Mun‑Yee Ko, Valen Zhuoyou Yu, Lvwen Ning, Maria Li Lung
Article Number: 513
Published online on: 05 May 2021

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Review Open Access

Triple‑negative breast cancer: A run‑through of features, classification and current therapies (Review)

Meghana Manjunath, Bibha Choudhary
Article Number: 512
Published online on: 05 May 2021

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Correction Open Access

[Corrigendum] Trifluridine/tipiracil increases survival rates in peritoneal dissemination mouse models of human colorectal and gastric cancer

Norihiko Suzuki, Fumio Nakagawa, Teiji Takechi
Article Number: 511
Published online on: 05 May 2021

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Review

Multiple strategies to improve the therapeutic efficacy of oncolytic herpes simplex virus in the treatment of glioblastoma (Review)

Zhengjun Zhou, Junjie Tian, Wenyan Zhang, Wei Xiang, Yang Ming, Ligang Chen, Jie Zhou
Article Number: 510
Published online on: 03 May 2021

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Article Open Access

Arsenic trioxide‑induced cell apoptosis and cell cycle arrest are potentiated by 1,25‑dihydroxyvitamin D3 in human leukemia K562 cells

Ya-Li Zhang, Shu-Kai Qiao, Xiao-Nan Guo, Jin-Hai Ren, Jing-Nan Zhang
Article Number: 509
Published online on: 03 May 2021

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Article Open Access

Suppression of circulating AP001429.1 long non‑coding RNA in obese patients with breast cancer

Hani Choudhry, Mohammed A. Hassan, Abdulrahman L. Al‑Malki, Kaltoom A. Al‑Sakkaf
Article Number: 508
Published online on: 03 May 2021

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Article Open Access

MicroRNA‑891a‑5p is a novel biomarker for non‑small cell lung cancer and targets HOXA5 to regulate tumor cell biological function

Nianqing Wan, Jianxiao Zheng
Article Number: 507
Published online on: 02 May 2021

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Article Open Access

Screening and potential role of tRFs and tiRNAs derived from tRNAs in the carcinogenesis and development of lung adenocarcinoma

Jinhua Zhang, Linhui Li, Lilin Luo, Xuantao Yang, Juanjuan Zhang, Yuxin Xie, Rui Liang, Wanpu Wang, Shuaiyao Lu
Article Number: 506
Published online on: 02 May 2021

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Article Open Access

Long non‑coding RNA USP30‑AS1 aggravates the malignant progression of cervical cancer by sequestering microRNA‑299‑3p and thereby overexpressing PTP4A1

Mengyue Chen, Yugang Chi, Hongwei Chen, Limei Zhao
Article Number: 505
Published online on: 29 April 2021

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Review

Role of the IL‑33/ST2 receptor axis in ovarian cancer progression (Review)

Ning Liu, Jintong Chen, Yinghua Zhao, Mingyue Zhang, Li Piao, Siqing Wang, Ying Yue
Article Number: 504
Published online on: 29 April 2021

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Article Open Access

HMGB1 knockdown increases the radiosensitivity of esophageal squamous cell carcinoma by regulating the expression of molecules involved in DNA repair

Guohu Han, Rui Ling, Changchun Sun, Xuefeng Wang, Yuepeng Zhou, Lijiang Yu, Shenzha Liu
Article Number: 503
Published online on: 29 April 2021

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Article Open Access

miR‑4417 targets lncRNA PSMG3‑AS1 to suppress cell invasion and migration in cervical squamous cell carcinoma

Shuhong Man, Xiaohan Li, Wei Zhu
Article Number: 502
Published online on: 29 April 2021

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Article Open Access

Antimicrobial peptide 17BIPHE2 inhibits the proliferation of lung cancer cells in vitro and in vivo by regulating the ERK signaling pathway

Tingting Yang, Jun Li, Qinqin Jia, Shisheng Zhan, Qiannan Zhang, Yarong Wang, Xiuqing Wang
Article Number: 501
Published online on: 28 April 2021

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Article Open Access

Long non‑coding RNA TMPO‑AS1 facilitates chemoresistance and invasion in breast cancer by modulating the miR‑1179/TRIM37 axis

Xiaojie Ning, Jianguo Zhao, Fan He, Yuan Yuan, Bin Li, Jian Ruan
Article Number: 500
Published online on: 28 April 2021

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Article Open Access

Expression and prognostic value of epithelial‑to‑mesenchymal transition and cancer stem cellmarkersin primary lesions and liver metastases of colorectal cancers

Cong Li, Ji-Yan Liu, Dan Jiang, Meng Qiu
Article Number: 499
Published online on: 27 April 2021

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Article Open Access

Comprehensive co‑expression analysis reveals TMC8 as a prognostic immune‑associated gene in head and neck squamous cancer

Bo Lin, Shunji Wang, Youdan Yao, Yuehong Shen, Hongyu Yang
Article Number: 498
Published online on: 27 April 2021

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Article Open Access

SOX9 is associated with advanced T-stages of clinical stage II colon cancer in young Mexican patients

Erik Lizárraga-Verdugo, Tatiana Galicia Carmona, Rosalío Ramos-Payan, Mariana Avendaño-Félix, Mercedes Bermúdez, Maryelv Parra-Niebla, César López-Camarillo, Edith Fernandez-Figueroa, Leonardo Lino-Silva, Herminia Arvelo Saavedra, Itzel Vela-Sarmiento, Roberto Cárdenas Ovando, Erika Ruíz-García, Maribel Aguilar-Medina
Article Number: 497
Published online on: 27 April 2021

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Review Open Access

Possibility of inducing tumor cell senescence during therapy (Review)

Guohui Wang, Xianliang Cheng, Jingyi Zhang, Yuan Liao, Yinnong Jia, Chen Qing
Article Number: 496
Published online on: 27 April 2021

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Article

DUXAP8 knockdown inhibits the development of melanoma by regulating the miR‑3182/NUPR1 pathway

Xige Chen, Juan Gao, Ning Liang
Article Number: 495
Published online on: 27 April 2021

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Journal Cover
April-2026 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Proliferative escalation and possible neuroendocrine carcinoma transformation in pulmonary metastases of a cervical neuroendocrine tumor: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Yuji Nitta, Tomoko Uchiyama, Akihiko Yoshizawa, Ryo Miyata, Masatsugu Hamaji, Hirotaka Kajihara, Masayuki Takeda
Article Number: 148
Published online on: 25 February 2026

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Gliosarcoma of the right cerebellar hemisphere and parahippocampal region: A case report and literature review

Fa Wu, Yulin Yang, Zaiqing Wang, Rui Jiang, Tingting Wu, Ting Yu, Peng Wang
Article Number: 147
Published online on: 25 February 2026

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Article Open Access

Preliminary evidence for the integration of CNAs, CN‑LOH and mutational profiles into the prognostic stratification of elderly patients with NPM1‑mutated acute myeloid leukemia

Li Gao, Chunxia Zhang, Ming Gong, Zhengyi Cao, Chundi Liu, Sijie Wang, Zhenling Li
Article Number: 146
Published online on: 25 February 2026

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Article Open Access

Pro‑tumourigenic effects of DCAF13 on the progression of colorectal cancer

Wenqi Zhang, Rongrong Zhang, Mengxuan Jia, Shuting Lan, Fangyuan Liu, Qin Jin, Liya Su, Gang Liu
Article Number: 145
Published online on: 25 February 2026

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Review Open Access

Histone deacetylases: Function in tumor development and therapeutic prospects (Review)

Runling Lin, Yu Zhang, Hong Li, Fan Liang
Article Number: 144
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Role of EphA2‑PI3K signaling in vasculogenic mimicry induced by cancer‑associated fibroblasts in gastric cancer cells

Hee Sung Kim, You Jin Won, Ju Hee Shim, Hyun Ji Kim, Byung Sik Kim, Hea Nam Hong
Article Number: 143
Published online on: 24 February 2026

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Case Report

Gastric cancer in pregnancy: A case report

Jianhua Niu, Yan Gao, Yu Sun, Huixia Yang
Article Number: 142
Published online on: 24 February 2026

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Correction Open Access

[Corrigendum] Potassium increases the antitumor effects of ascorbic acid in breast cancer cell lines in vitro

Giovanni Vanni Frajese, Monica Benvenuto, Massimo Fantini, Elena Ambrosin, Pamela Sacchetti, Laura Masuelli, Maria Gabriella Giganti, Andrea Modesti, Roberto Bei
Article Number: 141
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑298 inhibits malignant phenotypes of epithelial ovarian cancer by regulating the expression of EZH2

Fenmei Zhou, Juan Chen, Hairong Wang
Article Number: 140
Published online on: 16 February 2026

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Case Report Open Access

Penile metastasis from prostate cancer with CDK12 mutation: A case report and literature review

Qi Xiang, Yanwu Wang, Bin Yao, Huiwen Tang, Qiang Dang
Article Number: 139
Published online on: 16 February 2026

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Case Report

Successful treatment with tepotinib followed by pembrolizumab in pulmonary pleomorphic carcinoma harbouring a MET exon 14 skipping mutation: A case report

Susumu Tanaka, Yu Saida, Yumi Ando, Jun Arinami, Ryo Yamazaki, Tomoya Wakabayashi, Hiroki Watanabe, Kohei Kushiro, Ryo Suzuki, Naohiro Yanagimura, Masashi Arita, Miyuki Sato, Tomohiro Tanaka, Koichiro Nozaki, Satoshi Watanabe, Shuhei Kondo, Hajime Umezu, Toshiaki Kikuchi
Article Number: 138
Published online on: 12 February 2026

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Article Open Access

METTL5‑mediated m6A modification of 18S rRNA drives oral squamous cell carcinoma progression by enhancing CCND3 translation

Lianlian Liu, Surui Sheng, Xin Zheng, Shuojin Huang, Lu Wang, Dalong Shu, Leile Tang, Qianting He
Article Number: 137
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 136
Published online on: 12 February 2026

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Review Open Access

STOML2 promotes hepatocellular carcinoma cell proliferation, invasion and migration by activating the PI3K/AKT signaling pathway (Review)

Mengyan Li, Jianli Chen
Article Number: 135
Published online on: 11 February 2026

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Article

Fatty acid‑induced lipid accumulation promotes radiosensitization in Huh7 hepatocellular carcinoma cells

Haruto Tanaka, Yasushi Mariya, Satoru Monzen
Article Number: 134
Published online on: 11 February 2026

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Article Open Access

Lactylation‑based machine algorithm combined with multi‑omics analysis to predict prognosis in cervical cancer

Ruyue Wang, Li Ning, Xiu Li, Yating Xu, Yu Si, Hongting Zhao, Qingling Ren
Article Number: 133
Published online on: 11 February 2026

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Article Open Access

Potential treatment benefits of a GLP‑1R antagonist in combination with immune checkpoint inhibitors in colorectal cancer

Zengqin Zhan, Chuncha Zhan, Lianqiao Li, Dan Lan, Guya Meng, Fan Chen
Article Number: 132
Published online on: 10 February 2026

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Article

Effect of the hsa‑microRNA 200c‑3p/ZEB1 loop in epithelial‑mesenchymal transition of ovarian cancer cells

Merve Senturk, Ece Gumusoglu‑Acar, Samet Topuz, Tuba Gunel
Article Number: 131
Published online on: 10 February 2026

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Article Open Access

Inhibition of IRE1α kinase increases ferroptosis resistance in triple‑negative breast cancer cells

Shuo Xu, Si-Qi Yang
Article Number: 130
Published online on: 10 February 2026

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Retraction Open Access

[Retracted] MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS

Yi Xiao, Taoran Deng, Changliang Su, Zhen Shang
Article Number: 129
Published online on: 09 February 2026

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Case Report Open Access

Metastatic breast cancer in primary lung cancer with compound EGFR mutations: A case report

Tianyao Yang, Yifan Xu, Xi Lin, Guodong Chen, Fangfang Wang
Article Number: 128
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] miR‑185 enhances the inhibition of proliferation and migration induced by ionizing radiation in melanoma

Jinpeng He, Ning Tian, Yanli Yang, Liangliang Jin, Xiu Feng, Junrui Hua, Sulan Lin, Bing Wang, He Li, Jufang Wang
Article Number: 127
Published online on: 04 February 2026

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Review Open Access

Advances in targeting vasculogenic mimicry in malignant tumors using monomeric compounds from Traditional Chinese Medicine (Review)

Fang-Yuan Liu, Yu-Qian Fu, Dan-Ni Ding, Shao-Xuan Liu, Yu-Xin Zhao, Ying Shen, Jia Li
Article Number: 126
Published online on: 03 February 2026

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Article Open Access

Preoperative lymphocyte‑albumin‑monocyte index as an inflammation‑ and nutrition‑based predictor of overall survival in triple‑negative breast cancer: A retrospective cohort study

Boxiang Zhang, Kuan Wang, Maihemuti Aishanjiang, Fang Lan, Binlin Ma
Article Number: 125
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] Epithelial cell adhesion molecule is overexpressed in hypopharyngeal carcinoma and suppresses the metastasis and proliferation of the disease when downregulated

Yakui Mu, Na Sa, Liang Yu, Sumei Lu, Haibo Wang, Wei Xu
Article Number: 124
Published online on: 02 February 2026

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Review Open Access

Combination of extracellular vesicles and organoids as a prospective model for cancer research (Review)

Jia Cao, Yanan Xu, Yuhan Gao, Xing Li, Libin Wang
Article Number: 123
Published online on: 30 January 2026

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Case Report Open Access

Malignant adenomyoepithelioma with HRAS G13R mutation: A case report

Hiroko Kuwabara, Reika Takeda, Yoshitaka Utsumi, Toshitaka Nagao, Kosei Kimura, Yoshinobu Hirose, Mitsuhiko Iwamoto
Article Number: 122
Published online on: 30 January 2026

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Case Report Open Access

Recurrent microsatellite instability‑high thymic carcinoma showing complete response to immune checkpoint inhibitor: A case report

Tomoki Nakagawa, Naohiro Aruga, Hajime Watanabe, Ryota Masuda, Shunsuke Yamada, Masayuki Iwazaki
Article Number: 121
Published online on: 29 January 2026

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Correction Open Access

[Corrigendum] Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis  

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 120
Published online on: 28 January 2026

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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