|
1
|
Alhazmi N, Pai CP, Albaqami A, Wang H,
Zhao X, Chen M, Hu P, Guo S, Starost K, Hajihassani O, et al: The
promyelocytic leukemia protein isoform PML1 is an oncoprotein and a
direct target of the antioxidant sulforaphane (SFN). Biochim
Biophys Acta Mol Cell Res. 1867:1187072020. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Li S, Yang Y, Sargsyan D, Wu R, Yin R, Kuo
HD, Yang I, Wang L, Cheng D, Ramirez CN, et al: Epigenome,
transcriptome and protection by sulforaphane at different stages of
UVB-induced skin carcinogenesis. Cancer Prev Res (Phila).
13:551–562. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Mastuo T, Miyata Y, Yuno T, Mukae Y,
Otsubo A, Mitsunari K, Ohba K and Sakai H: Molecular mechanisms of
the anti-cancer effects of isothiocyanates from cruciferous
vegetables in bladder cancer. Molecules. 25:5752020. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Zhang Z, Garzotto M, Davis EW II, Mori M,
Stoller WA, Farris PE, Wong CP, Beaver LM, Thomas GV, Williams DE,
et al: Sulforaphane bioavailability and chemopreventive activity in
men presenting for biopsy of the prostate gland: A randomized
controlled trial. Nutr Cancer. 72:74–87. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Gasparello J, Gambari L, Papi C, Rozzi A,
Manicardi A, Corradini R, Gambari R and Finotti A: High levels of
apoptosis are induced in the human colon cancer HT-29 cell line by
co-administration of sulforaphane and a peptide nucleic acid
targeting miR-15b-5p. Nucleic Acid Ther. 30:164–174. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Desai P, Wang KZ, Ann D, Wang J and Prabhu
S: Efficacy and pharmacokinetic considerations of loratadine
nanoformulations and its combinations for pancreatic cancer
chemoprevention. Pharm Res. 37:212020. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Dos Santos PWDS, Machado ART, De Grandis
RA, Ribeiro DL, Tuttis K, Morselli M, Aissa AF, Pellegrini M and
Antunes LMG: Transcriptome and DNA methylation changes modulated by
sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and
suppression of proliferation in human liver cancer cells. Food Chem
Toxicol. 136:1110472020. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ,
Zhu JY, Xie CF, Li XT, Zhong CY and Han HY: Sulforaphane inhibits
epithelial-mesenchymal transition by activating extracellular
signal-regulated kinase 5 in lung cancer cells. J Nutr Biochem.
72:1082192019. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen L, Chan LS, Lung HL, Yip TTC, Ngan
RKC, Wong JWC, Lo KW, Ng WT, Lee AWM, Tsao GSW, et al: Crucifera
sulforaphane (SFN) inhibits the growth of nasopharyngeal carcinoma
through DNA methyltransferase 1 (DNMT1)/Wnt inhibitory factor 1
(WIF1) axis. Phytomedicine. 63:1530582019. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tian M, Tian D, Qiao X, Li J and Zhang L:
Modulation of Myb-induced NF-kB-STAT3 signaling and resulting
cisplatin resistance in ovarian cancer by dietary factors. J Cell
Physiol. 234:21126–21134. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Li S, Chen M, Wu H, Li Y and Tollefsbol
TO: Maternal epigenetic regulation contributes to prevention of
estrogen receptor-negative mammary cancer with broccoli sprout
consumption. Cancer Prev Res (Phila). 13:449–462. 2020.PubMed/NCBI
|
|
12
|
Hussain A, Priyani A, Sadrieh L,
Brahmbhatt K, Ahmed M and Sharma C: Concurrent sulforaphane and
eugenol induces differential effects on human cervical cancer
cells. Integr Cancer Ther. 11:154–165. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Li D, Shao R, Wang N, Zhou N, Du K, Shi J,
Wang Y, Zhao Z, Ye X, Zhang X and Xu H: Sulforaphane activates a
lysosome-dependent transcriptional program to mitigate oxidative
stress. Autophagy. 17:872–887. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Juge N, Mithen RF and Traka M: Molecular
basis for chemoprevention by sulforaphane: A comprehensive review.
Cell Mol Life Sci. 64:1105–1127. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Zhang Y and Talalay P: Mechanism of
differential potencies of isothiocyanates as inducers of
anticarcinogenic phase 2 enzymes. Cancer Res. 58:4632–4639.
1998.PubMed/NCBI
|
|
16
|
Kamal MM, Akter S, Lin CN and Nazzal S:
Sulforaphane as an anticancer molecule: Mechanisms of action,
synergistic effects, enhancement of drug safety, and delivery
systems. Arch Pharm Res. 43:371–384. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Clarke JD, Dashwood RH and Ho E:
Multi-targeted prevention of cancer by sulforaphane. Cancer Lett.
269:291–304. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Xu Y, Han X, Li Y, Min H, Zhao X, Zhang Y,
Qi Y, Shi J, Qi S, Bao Y and Nie G: Sulforaphane mediates
glutathione depletion via polymeric nanoparticles to restore
cisplatin chemosensitivity. ACS Nano. 13:13445–13455. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Pocasap P, Weerapreeyakul N and Thumanu K:
Structures of isothiocyanates attributed to reactive oxygen species
generation and microtubule depolymerization in HepG2 cells. Biomed.
Pharmacother. 101:698–709. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zhang C, Zhang J, Wu Q, Xu B, Jin G, Qiao
Y, Zhao S, Yang Y, Shang J, Li X and Liu K: Sulforaphene induces
apoptosis and inhibits the invasion of esophageal cancer cells
through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro.
Cancer Cell Int. 19:3422019. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Yang M, Wang H, Zhou M, Liu W, Kuang P,
Liang H and Yuan Q: The natural compound sulforaphene, as a novel
anticancer reagent, targeting PI3K-AKT signaling pathway in lung
cancer. Oncotarget. 7:76656–76666. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Byun S, Shin SH, Park J, Lim S, Lee E, Lee
C, Sung D, Farrand L, Lee SR, Kim KH, et al: Sulforaphene
suppresses growth of colon cancer-derived tumors via induction of
glutathione depletion and microtubule depolymerization. Mol Nutr
Food Res. 60:1068–1078. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Mondal A, Biswas R, Rhee YH, Kim J and Ahn
JC: Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric
cancer AGS cells apoptosis and inhibits migration via EGFR,
p-ERK1/2 down-regulation. Gen Physiol Biophys. 35:25–34.
2016.PubMed/NCBI
|
|
24
|
Pawlik A, Wała M, Hać A, Felczykowska A
and Herman-Antosiewicz A: Sulforaphene, an isothiocyanate present
in radish plants, inhibits proliferation of human breast cancer
cells. Phytomedicine. 29:1–10. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Biswas R, Mondal A, Chatterjee S and Ahn
JC: Evaluation of synergistic effects of sulforaphene with
photodynamic therapy in human cervical cancer cell line. Lasers Med
Sci. 31:1675–1682. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Chatterjee S, Rhee Y, Chung PS, Ge RF and
Ahn JC: Sulforaphene enhances the efficacy of photodynamic therapy
in anaplastic thyroid cancer through Ras/RAF/MEK/ERK pathway
suppression. J Photochem Photobiol B. 179:46–53. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Baechler EC, Batliwalla FM, Karypis G,
Gaffney PM, Moser K, Ortmann WA, Espe KJ, Balasubramanian S, Hughes
KM, Chan JP, et al: Expression levels for many genes in human
peripheral blood cells are highly sensitive to ex vivo incubation.
Genes Immun. 5:347–353. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Chen W, Zheng R, Baade PD, Zhang S, Zeng
H, Bray F, Jemal A, Yu XQ and He J: Cancer statistics in China,
2015. CA Cancer J Clin. 66:115–132. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Ko MO, Kim MB and Lim SB: Relationship
between chemical structure and antimicrobial activities of
isothiocyanates from cruciferous vegetables against oral pathogens.
J Microbiol Biotechnol. 26:2036–2042. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Kim KH, Moon E, Kim SY, Choi SU, Lee JH
and Lee KR: 4-Methylthio-butanyl derivatives from the seeds of
raphanus sativus and their biological evaluation on
anti-inflammatory and antitumor activities. J Ethnopharmacol.
151:503–508. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Yang H, Kang MJ, Hur G, Lee TK, Park IS,
Seo SG, Yu JG, Song YS, Park JHY and Lee KW: Sulforaphene
suppresses adipocyte differentiation via induction of
post-translational degradation of CCAAT/enhancer binding protein
beta (C/EBPβ). Nutrients. 12:7582020. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Zhang J, Feng C, Tan X, Hagedoorn PL, Gu
C, Xu H and Zhou X: Effect of aliphatic diamine spacer length on
enzymatic performance of myrosinase immobilized on chitosan
microsphere and its application for sulforaphene production. J
Biotechnol. 299:79–85. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Chen J, Bao C, Kim JT, Cho JS, Qiu S and
Lee HJ: Sulforaphene inhibition of adipogenesis via Hedgehog
signaling in 3T3-L1 adipocytes. J Agric Food Chem. 66:11926–11934.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Rai R, Gong Essel K, Mangiaracina Benbrook
D, Garland J, Daniel Zhao Y and Chandra V: Preclinical efficacy and
involvement of AKT, mTOR, and ERK kinases in the mechanism of
sulforaphane against endometrial cancer. Cancers (Basel).
12:12732020. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Biswas R, Ahn JC and Kim JS: Sulforaphene
synergistically sensitizes cisplatin via enhanced mitochondrial
dysfunction and PI3K/PTEN modulation in ovarian cancer cells.
Anticancer Res. 35:3901–3908. 2015.PubMed/NCBI
|
|
37
|
Farooqi AA, de la Roche M, Djamgoz MBA and
Siddik ZH: Overview of the oncogenic signaling pathways in
colorectal cancer: Mechanistic insights. Semin Cancer Biol.
58:65–79. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Mármol I, Sánchez-de-Diego C, Pradilla
Dieste A, Cerrada E and Rodriguez Yoldi MJ: Colorectal carcinoma: A
general overview and future perspectives in colorectal cancer. Int
J Mol Sci. 18:1972017. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Chiacchiera F, Matrone A, Ferrari E,
Ingravallo G, Lo Sasso G, Murzilli S, Petruzzelli M, Salvatore L,
Moschetta A and Simone C: p38alpha blockade inhibits colorectal
cancer growth in vivo by inducing a switch from HIF1alpha-to
FoxO-dependent transcription. Cell Death Differ. 16:1203–1214.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Li Q, Tang H, Hu F and Qin C: Silencing of
FOXO6 inhibits the proliferation, invasion, and glycolysis in
colorectal cancer cells. J Cell Biochem. 120:3853–3860. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Krishnamurthy N and Kurzrock R: Targeting
the Wnt/beta-catenin pathway in cancer: Update on effectors and
inhibitors. Cancer Treat Rev. 62:50–60. 2018. View Article : Google Scholar : PubMed/NCBI
|
