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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2021 Volume 22 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura
Article Number: 744
Published online on: 20 August 2021

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Pioglitazone mediates apoptosis in Caki cells via downregulating c‑FLIP(L) expression and reducing Bcl‑2 protein stability

Ji Hoon Jang, Tae-Jin Lee, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim
Article Number: 743
Published online on: 20 August 2021

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Article Open Access

Gold nanoparticles enhance microRNA 31 detection in colon cancer cells after inhibition with chlorogenic acid

Ana C. Luque‑Badillo, Griselda Hernandez‑Tapia, Dhamar A. Ramirez‑Castillo, Diego Espinoza‑Serrano, Alan M. Cortes‑Limon, Juan P. Cortes‑Gallardo, Daniel A. Jacobo‑Velázquez, Margarita L. Martinez‑Fierro, Clara P. Rios‑Ibarra
Article Number: 742
Published online on: 19 August 2021

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Correction Open Access

[Corrigendum] MicroRNA‑100 functions as a tumor suppressor in cervical cancer via downregulating the SATB1 expression and regulating AKT/mTOR signaling pathway and epithelial‑to‑mesenchymal transition

Cuiping Huang, Xiaobo Qin, Na Zhao, Huijing Jin, Shuangjun Zhang, Haiyan Yang
Article Number: 741
Published online on: 17 August 2021

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Article

Lanatoside C inhibits human cervical cancer cell proliferation and induces cell apoptosis by a reduction of the JAK2/STAT6/SOCS2 signaling pathway

Yingchun Duan, Li Chen, Juan Shao, Cui Jiang, Yingmei Zhao, Yanyi Li, Huihui Ke, Rui Zhang, Jianlong Zhu, Minghua Yu
Article Number: 740
Published online on: 17 August 2021

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Article Open Access

Upregulation of microfibrillar‑associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma

Nu Zhang, Feng Shao, Weidong Jia
Article Number: 739
Published online on: 16 August 2021

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Article Open Access

Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice

Yukino Machida, Toshio Imai
Article Number: 738
Published online on: 16 August 2021

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Article Open Access

TAGLN2 promotes the proliferation, invasion, migration and epithelial‑mesenchymal transition of colorectal cancer cells by activating STAT3 signaling through ANXA2

Zhicheng Zhao, Li Lu, Weidong Li
Article Number: 737
Published online on: 16 August 2021

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Article Open Access

ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway

Shengjin Yu, Shidan Wang, Xiaoxin Sun, Yinshuang Wu, Jun Zhao, Junqiang Liu, Deyong Yang, Yu Jiang
Article Number: 736
Published online on: 12 August 2021

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Article Open Access

Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells

Naoki Ikari, Akiko Serizawa, Etsuko Tanji, Masakazu Yamamoto, Toru Furukawa
Article Number: 735
Published online on: 11 August 2021

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Review

Current evidence on laparoscopic vs. open resection for gastric stromal tumours (Review)

Christos Iordanou, Charalampos A. Theodoridis, Panagis M. Lykoudis, Dimitrios Dimitroulis, Nikolaos Machairas, Eleftherios Spartalis, Pinelopi Kouki, Emmanouil Pikoulis, Nikolaos Nikiteas
Article Number: 734
Published online on: 11 August 2021

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Article Open Access

A nuclear polymorphism at the 8q24 region is associated with improved survival time and chemo‑response in high‑grade serous ovarian cancer

Danielle Ikoma, Nicholas Cardillo, Eric Devor, Jesus Gonzalez‑Bosquet
Article Number: 733
Published online on: 11 August 2021

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Article Open Access

CDK4 has the ability to regulate Aurora B and Cenpp expression in mouse keratinocytes

Sung Hyun Lee, Liliana R.l. Rodriguez, Rima Majumdar, Paula L. Miliani De Marval, Marcelo L. Rodriguez‑Puebla
Article Number: 732
Published online on: 11 August 2021

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Review Open Access

Emerging role of SIRT2 in non-small cell lung cancer (Review)

Mengge Zheng, Changyong Hu, Meng Wu, Yue Eugene Chin
Article Number: 731
Published online on: 11 August 2021

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Article Open Access

Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma

Yasutaka Itashiki, Koji Harada, Takanori Takenawa, Tarannum Ferdous, Yoshiya Ueyama, Katsuaki Mishima
Article Number: 730
Published online on: 11 August 2021

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Article

MicroRNA‑27b‑3p inhibits the proliferation and invasion of cutaneous squamous cell carcinoma by targeting EGFR and MMP‑13

Daning Liang, Zhenning Zhang
Article Number: 729
Published online on: 10 August 2021

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Article

The effects of BAFF and APRIL signaling on non‑small cell lung cancer cell proliferation and invasiveness

Martyna Warakomska, Marlena Tynecka, Dorota Lemancewicz, Kamil Grubczak, Janusz Dzieciol, Marcin Moniuszko, Andrzej Eljaszewicz, Lukasz Bolkun
Article Number: 728
Published online on: 10 August 2021

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Article Open Access

LncRNA GAS6 antisense RNA 1 facilitates the tumorigenesis of clear cell renal cell carcinoma by regulating the AMP‑activated protein kinase/mTOR signaling pathway Retraction in /10.3892/ol.2024.14259

Xiaoyun Guo, Hongjun Li, Mei Zhang, Rong Li
Article Number: 727
Published online on: 10 August 2021

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Article Open Access

Osthole induces apoptosis of the HT‑29 cells via endoplasmic reticulum stress and autophagy

Xing-Hua Zhou, Jian Kang, Zhen-Dong Zhong, Yue Cheng
Article Number: 726
Published online on: 10 August 2021

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Article Open Access

Efficacy of circulating microRNA‑130b and blood routine parameters in the early diagnosis of gastric cancer

Jianlin Chen, Zhaohui Liu, Gan Gao, Yuandong Mo, Hongling Zhou, Wenjie Huang, Lihua Wu, Xiaoling He, Junping Ding, Changjun Luo, Haihua Long, Jingrong Feng, Yifan Sun, Xiaoyong Guan
Article Number: 725
Published online on: 10 August 2021

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Article Open Access

Verteporfin suppresses osteosarcoma progression by targeting the Hippo signaling pathway

Xianliang Yang, Youjia Xu, Chao Jiang, Ziping Ma, Linguang Jin
Article Number: 724
Published online on: 10 August 2021

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Review Open Access

Role of the CTRP family in tumor development and progression (Review)

Mowei Kong, Yu Gao, Xiang Guo, Yuyu Xie, Yamei Yu
Article Number: 723
Published online on: 10 August 2021

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Article Open Access

Circular RNA SLC26A4 regulates the maturation of microRNA‑15a in non‑small cell lung cancer cells

Qiankun Chen, Hua Li, Ji Liu
Article Number: 722
Published online on: 10 August 2021

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Article Open Access

Histone deacetylase 1 facilitates aerobic glycolysis and growth of endometrial cancer

Qiongwei Wu, Wenying Zhang, Yu Liu, Yuhua Huang, Huiheng Wu, Chengbin Ma
Article Number: 721
Published online on: 10 August 2021

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Article Open Access

GADD45α alleviates the CDDP resistance of SK‑OV3/cddp cells via redox‑mediated DNA damage

Qi-Zhu Zhang, Fang Wen, Han-Lin Yang, Yan-Yan Cao, Ren Guo Peng, Yuan-Mei Wang, Lei Nie, Yuan-Kun Qin, Jin-Jian Wu, Xing Zhao, Dan Zi
Article Number: 720
Published online on: 10 August 2021

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Article Open Access

Identification of GNA12‑driven gene signatures and key signaling networks in ovarian cancer

Ji-Hee Ha, Muralidharan Jayaraman, Mingda Yan, Padmaja Dhanasekaran, Ciro Isidoro, Yong-Sang Song, Danny N. Dhanasekaran
Article Number: 719
Published online on: 10 August 2021

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Article Open Access

GATA6‑AS1 inhibits ovarian cancer cell proliferation and migratory and invasive abilities by sponging miR‑19a‑5p and upregulating TET2

Hua Xu, Xiao Wang, Yinghong Zhang, Wei Zheng, Huijie Zhang
Article Number: 718
Published online on: 09 August 2021

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Article Open Access

Identification of prognostic long intergenic non‑coding RNAs as competing endogenous RNAs with KRAS mutations in colorectal cancer

Jun Xu, Qiu-Yun Huang, Cun-Jin Ge
Article Number: 717
Published online on: 09 August 2021

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Article

Interleukin‑22 promotes PD‑L1 expression via STAT3 in colon cancer cells

Xiangpeng Xi, Rui Hu, Qi Wang, Kang Xu, Hui Yang, Zhonghui Cui, Yongbo Zhang, Mujian Teng, Lijian Xia, Jingbo Chen, Yulin Liu
Article Number: 716
Published online on: 08 August 2021

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Article Open Access

Metformin mitigates PLCε gene expression and modulates the Notch1/Hes and androgen receptor signaling pathways in castration‑resistant prostate cancer xenograft models Retraction in /10.3892/ol.2025.15082

Qi Li, Ke Xu, Jianguo Tian, Zhicheng Lu, Jianming Pu
Article Number: 715
Published online on: 08 August 2021

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Article Open Access

Comprehensive analysis of differentially expressed genes reveals the promotive effects of UBE2T on colorectal cancer cell proliferation

Min Luo, Yuqian Zhou
Article Number: 714
Published online on: 06 August 2021

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Article Open Access

SPP1 and FN1 are significant gene biomarkers of tongue squamous cell carcinoma

Xiao-Liang Xu, Hui Liu, Ying Zhang, Su-Xin Zhang, Zhong Chen, Yang Bao, Tian-Ke Li
Article Number: 713
Published online on: 06 August 2021

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Article

FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 712
Published online on: 05 August 2021

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Article Open Access

RNA m6A methyltransferase METTL3 promotes colorectal cancer cell proliferation and invasion by regulating Snail expression

Jianfan Wen, Guowei Zhang, Yuwen Meng, Lei Zhang, Min Jiang, Zhitao Yu
Article Number: 711
Published online on: 05 August 2021

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Article Open Access

Overexpression of E74‑like transformation‑specific transcription factor 3 promotes cellular proliferation and predicts poor prognosis in ovarian cancer

Yao Liu, Shourong Wang, Ruiqi Zhou, Wenxue Li, Guiyu Zhang
Article Number: 710
Published online on: 05 August 2021

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Article Open Access

Association between miR‑212‑3p and SOX11, and the effects of miR‑212‑3p on cell proliferation and migration in mantle cell lymphoma

Yuyang Tian, Li Wang, Yanming Zhang, Lianqiao Li, Yingying Fei, Xingxia Zhang, Guoqiang Lin
Article Number: 709
Published online on: 05 August 2021

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Article Open Access

Small heterodimer partner as a predictor of neoadjuvant radiochemotherapy response and survival in patients with rectal cancer: A preliminary study

Sup Kim, Mina Joo, Min-Kyung Yeo, Moon-June Cho, Jun-Sang Kim, Eun-Kyeong Jo, Jin-Man Kim
Article Number: 708
Published online on: 04 August 2021

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Article Open Access

Effect and mechanism of action of SLP‑2 on the apoptosis and autophagy of gastric cancer cells

Shengsen Yang, Yun Huang, Hongyan Zhang, Fang Wang, Liangui Shao, Xuehong Wang
Article Number: 707
Published online on: 04 August 2021

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Article Open Access

Proteome profiling of formalin‑fixed, paraffin‑embedded lung adenocarcinoma tissues using a tandem mass tag‑based quantitative proteomics approach

Qi Xie, Dan Wang, Xiao Luo, Zhen Li, Aixia Hu, Hui Yang, Jinxing Tang, Peiyu Gao, Tingyi Sun, Lingfei Kong
Article Number: 706
Published online on: 04 August 2021

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Article Open Access

Role of JNK activation in paclitaxel‑induced apoptosis in human head and neck squamous cell carcinoma

Yu-Yan Lan, Ying-Hui Chen, Cheng Liu, Kuo-Lung Tung, Yen-Ting Wu, Sheng-Chieh Lin, Chin-Han Wu, Hong-Yi Chang, Yung-Chia Chen, Bu-Miin Huang
Article Number: 705
Published online on: 03 August 2021

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Article Open Access

Circ_0074027 binds to EIF4A3 and promotes gastric cancer progression

Yuluo Wu, Haiyang Zhao
Article Number: 704
Published online on: 03 August 2021

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Article Open Access

Photosensitizer verteporfin inhibits the growth of YAP‑ and TAZ‑dominant gastric cancer cells by suppressing the anti‑apoptotic protein Survivin in a light‑independent manner

Takashi Hasegawa, Takaaki Sugihara, Yoshiki Hoshino, Ryohei Tarumoto, Yukako Matsuki, Tsutomu Kanda, Tomoaki Takata, Takakazu Nagahara, Tomomitsu Matono, Hajime Isomoto
Article Number: 703
Published online on: 03 August 2021

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Article Open Access

Characterization of tumor‑associated MUC1 and its glycans expressed in mucoepidermoid carcinoma

Eisaku Isaka, Takanori Sugiura, Kazuhiko Hashimoto, Kazutaka Kikuta, Ukei Anazawa, Takeshi Nomura, Akihiko Kameyama
Article Number: 702
Published online on: 03 August 2021

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Article Open Access

Lymphomatosis cerebri: Multimodality imaging features and misdiagnosis analysis

Zhibing Ruan, Lan Chu, Chunfeng Liu, Yu Hu, Jinjin Huang
Article Number: 701
Published online on: 03 August 2021

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Article Open Access

Combination of nigericin with cisplatin enhances the inhibitory effect of cisplatin on epithelial ovarian cancer metastasis by inhibiting slug expression via the Wnt/β‑catenin signalling pathway

Bin Zhou, Changlin Wang, Xiaobei Liu, Bin Wu, Jianwei Li, Shujuan Yao, Shiqian Zhang
Article Number: 700
Published online on: 03 August 2021

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Retraction Open Access

[Retracted] microRNA‑23a promotes cell growth and metastasis in gastric cancer via targeting SPRY2‑mediated ERK signaling

Yingjia Li, Hui Chen, Pengfei She, Ti Chen, Lihua Chen, Jinling Yuan, Botao Jiang
Article Number: 699
Published online on: 02 August 2021

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Correction Open Access

[Corrigendum] lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma

Hideharu Yamada, Masanobu Takahashi, Munenori Watanuki, Mika Watanabe, Sakura Hiraide, Ken Saijo, Keigo Komine, Chikashi Ishioka
Article Number: 698
Published online on: 02 August 2021

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Article Open Access

A micro‑peptide encoded by HOXB‑AS3 promotes the proliferation and viability of oral squamous cell carcinoma cell lines by directly binding with IGF2BP2 to stabilize c‑Myc

Fei Leng, Yan-Yu Miu, Yi Zhang, Hao Luo, Xiao-Li Lu, Hui Cheng, Zhi-Guo Zheng
Article Number: 697
Published online on: 02 August 2021

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Article Open Access

Cancer‑associated fibroblast‑derived CCL5 contributes to cisplatin resistance in A549 NSCLC cells partially through upregulation of lncRNA HOTAIR expression

Xiangjun Sun, Zhijie Chen
Article Number: 696
Published online on: 02 August 2021

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Article Open Access

miR‑425 regulates lipophagy via SIRT1 to promote sorafenib resistance in liver cancer

Gongping Sun, Liang Yang, Shibo Wei, Hongyuan Jin, Bowen Li, Hangyu Li
Article Number: 695
Published online on: 02 August 2021

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Article

Knockdown of NCOA5 suppresses viability, migration and epithelial‑mesenchymal transition, and induces adhesion of breast cancer cells

Yanfang Tan, Fuhui Liu, Pei Xu
Article Number: 694
Published online on: 01 August 2021

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Article Open Access

Identification of differentially expressed genes using microarray analysis and COL6A1 induction of bone metastasis in non‑small cell lung cancer

Nan Li, Ming Liu, Xiaohui Cao, Wei Li, Yunfang Li, Zongmao Zhao
Article Number: 693
Published online on: 01 August 2021

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Article Open Access

Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG‑1 human acute myeloid leukemia cell line and its mechanism

Ping He, Jian Lei, Li-Xin Zou, Gui-Zhen Zhou, Lang Peng, Qian Deng, Xiao-Liu Liu
Article Number: 692
Published online on: 01 August 2021

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Article Open Access

Penicillin disrupts mitochondrial function and induces autophagy in colorectal cancer cell lines

Fei Hu, Yu Wu, Cheng Liu, Yingchao Zhu, Shazhou Ye, Yang Xi, Wei Cui, Shizhong Bu
Article Number: 691
Published online on: 01 August 2021

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Article Open Access

Examination of the differences between sulforaphane and sulforaphene in colon cancer: A study based on next‑generation sequencing

Lei Gao, Fengying Du, Jinshen Wang, Yuhua Zhao, Junhua Liu, Da Cai, Xiao Zhang, Yutao Wang, Shuqiu Zhang
Article Number: 690
Published online on: 01 August 2021

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Article Open Access

Novel bone microenvironment model of castration‑resistant prostate cancer with chitosan fiber matrix and osteoblasts

Masahiro Samoto, Hideyasu Matsuyama, Hiroaki Matsumoto, Hiroshi Hirata, Koji Ueno, Sho Ozawa, Junichi Mori, Ryo Inoue, Seiji Yano, Yoshiaki Yamamoto, Jun Haginaka, Shizuyo Horiyama, Koji Tamada
Article Number: 689
Published online on: 01 August 2021

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Article Open Access

Dihydroartemisinin suppresses proliferation, migration, the Wnt/β‑catenin pathway and EMT via TNKS in gastric cancer Corrigendum in /10.3892/ol.2021.13152

Yanmei Ma, Peng Zhang, Qilong Zhang, Xiaofei Wang, Qiong Miao, Xiaolan Lyu, Bo Cui, Honghong Ma
Article Number: 688
Published online on: 29 July 2021

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Article Open Access

Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Article Open Access

Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Article Open Access

Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Article Open Access

Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Article Open Access

Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Article Open Access

Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Article Open Access

Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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Article Open Access

SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Article Open Access

Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Article Open Access

Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Article Open Access

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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