Journal Articles

Article Open Access

Repositioning of duloxetine to target pancreatic stellate cells

Akiko Sagara, Kohei Nakata, Sokichi Matsumoto, Weiyu Guan, Tomohiko Shinkawa, Chika Iwamoto, Naoki Ikenaga, Kenoki Ohuchida, Masafumi Nakamura

Article Number: 744 Published online on: 20 August 2021
Article Open Access

Pioglitazone mediates apoptosis in Caki cells via downregulating c‑FLIP(L) expression and reducing Bcl‑2 protein stability

Ji Hoon Jang, Tae-Jin Lee, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim

Article Number: 743 Published online on: 20 August 2021
Article Open Access

Gold nanoparticles enhance microRNA 31 detection in colon cancer cells after inhibition with chlorogenic acid

Ana C. Luque‑Badillo, Griselda Hernandez‑Tapia, Dhamar A. Ramirez‑Castillo, Diego Espinoza‑Serrano, Alan M. Cortes‑Limon, Juan P. Cortes‑Gallardo, Daniel A. Jacobo‑Velázquez, Margarita L. Martinez‑Fierro, Clara P. Rios‑Ibarra

Article Number: 742 Published online on: 19 August 2021
Correction Open Access
Article

Lanatoside C inhibits human cervical cancer cell proliferation and induces cell apoptosis by a reduction of the JAK2/STAT6/SOCS2 signaling pathway

Yingchun Duan, Li Chen, Juan Shao, Cui Jiang, Yingmei Zhao, Yanyi Li, Huihui Ke, Rui Zhang, Jianlong Zhu, Minghua Yu

Article Number: 740 Published online on: 17 August 2021
Article Open Access

ST8SIA1 inhibits the proliferation, migration and invasion of bladder cancer cells by blocking the JAK/STAT signaling pathway

Shengjin Yu, Shidan Wang, Xiaoxin Sun, Yinshuang Wu, Jun Zhao, Junqiang Liu, Deyong Yang, Yu Jiang

Article Number: 736 Published online on: 12 August 2021
Article Open Access

Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells

Naoki Ikari, Akiko Serizawa, Etsuko Tanji, Masakazu Yamamoto, Toru Furukawa

Article Number: 735 Published online on: 11 August 2021
Review

Current evidence on laparoscopic vs. open resection for gastric stromal tumours (Review)

Christos Iordanou, Charalampos A. Theodoridis, Panagis M. Lykoudis, Dimitrios Dimitroulis, Nikolaos Machairas, Eleftherios Spartalis, Pinelopi Kouki, Emmanouil Pikoulis, Nikolaos Nikiteas

Article Number: 734 Published online on: 11 August 2021
Article Open Access

A nuclear polymorphism at the 8q24 region is associated with improved survival time and chemo‑response in high‑grade serous ovarian cancer

Danielle Ikoma, Nicholas Cardillo, Eric Devor, Jesus Gonzalez‑Bosquet

Article Number: 733 Published online on: 11 August 2021
Article Open Access

CDK4 has the ability to regulate Aurora B and Cenpp expression in mouse keratinocytes

Sung Hyun Lee, Liliana R.l. Rodriguez, Rima Majumdar, Paula L. Miliani De Marval, Marcelo L. Rodriguez‑Puebla

Article Number: 732 Published online on: 11 August 2021
Review Open Access

Emerging role of SIRT2 in non-small cell lung cancer (Review)

Mengge Zheng, Changyong Hu, Meng Wu, Yue Eugene Chin

Article Number: 731 Published online on: 11 August 2021
Article Open Access

Antitumor effects of bevacizumab in combination with fluoropyrimidine drugs on human oral squamous cell carcinoma

Yasutaka Itashiki, Koji Harada, Takanori Takenawa, Tarannum Ferdous, Yoshiya Ueyama, Katsuaki Mishima

Article Number: 730 Published online on: 11 August 2021
Article

MicroRNA‑27b‑3p inhibits the proliferation and invasion of cutaneous squamous cell carcinoma by targeting EGFR and MMP‑13

Daning Liang, Zhenning Zhang

Article Number: 729 Published online on: 10 August 2021
Article

The effects of BAFF and APRIL signaling on non‑small cell lung cancer cell proliferation and invasiveness

Martyna Warakomska, Marlena Tynecka, Dorota Lemancewicz, Kamil Grubczak, Janusz Dzieciol, Marcin Moniuszko, Andrzej Eljaszewicz, Lukasz Bolkun

Article Number: 728 Published online on: 10 August 2021
Article Open Access

Osthole induces apoptosis of the HT‑29 cells via endoplasmic reticulum stress and autophagy

Xing-Hua Zhou, Jian Kang, Zhen-Dong Zhong, Yue Cheng

Article Number: 726 Published online on: 10 August 2021
Article Open Access

Efficacy of circulating microRNA‑130b and blood routine parameters in the early diagnosis of gastric cancer

Jianlin Chen, Zhaohui Liu, Gan Gao, Yuandong Mo, Hongling Zhou, Wenjie Huang, Lihua Wu, Xiaoling He, Junping Ding, Changjun Luo, Haihua Long, Jingrong Feng, Yifan Sun, Xiaoyong Guan

Article Number: 725 Published online on: 10 August 2021
Article Open Access

Verteporfin suppresses osteosarcoma progression by targeting the Hippo signaling pathway

Xianliang Yang, Youjia Xu, Chao Jiang, Ziping Ma, Linguang Jin

Article Number: 724 Published online on: 10 August 2021
Review Open Access

Role of the CTRP family in tumor development and progression (Review)

Mowei Kong, Yu Gao, Xiang Guo, Yuyu Xie, Yamei Yu

Article Number: 723 Published online on: 10 August 2021
Article Open Access

Circular RNA SLC26A4 regulates the maturation of microRNA‑15a in non‑small cell lung cancer cells

Qiankun Chen, Hua Li, Ji Liu

Article Number: 722 Published online on: 10 August 2021
Article Open Access

Histone deacetylase 1 facilitates aerobic glycolysis and growth of endometrial cancer

Qiongwei Wu, Wenying Zhang, Yu Liu, Yuhua Huang, Huiheng Wu, Chengbin Ma

Article Number: 721 Published online on: 10 August 2021
Article Open Access

GADD45α alleviates the CDDP resistance of SK‑OV3/cddp cells via redox‑mediated DNA damage

Qi-Zhu Zhang, Fang Wen, Han-Lin Yang, Yan-Yan Cao, Ren Guo Peng, Yuan-Mei Wang, Lei Nie, Yuan-Kun Qin, Jin-Jian Wu, Xing Zhao, Dan Zi

Article Number: 720 Published online on: 10 August 2021
Article Open Access

Identification of GNA12‑driven gene signatures and key signaling networks in ovarian cancer

Ji-Hee Ha, Muralidharan Jayaraman, Mingda Yan, Padmaja Dhanasekaran, Ciro Isidoro, Yong-Sang Song, Danny N. Dhanasekaran

Article Number: 719 Published online on: 10 August 2021
Article Open Access

GATA6‑AS1 inhibits ovarian cancer cell proliferation and migratory and invasive abilities by sponging miR‑19a‑5p and upregulating TET2

Hua Xu, Xiao Wang, Yinghong Zhang, Wei Zheng, Huijie Zhang

Article Number: 718 Published online on: 09 August 2021
Article Open Access

Identification of prognostic long intergenic non‑coding RNAs as competing endogenous RNAs with KRAS mutations in colorectal cancer

Jun Xu, Qiu-Yun Huang, Cun-Jin Ge

Article Number: 717 Published online on: 09 August 2021
Article

Interleukin‑22 promotes PD‑L1 expression via STAT3 in colon cancer cells

Xiangpeng Xi, Rui Hu, Qi Wang, Kang Xu, Hui Yang, Zhonghui Cui, Yongbo Zhang, Mujian Teng, Lijian Xia, Jingbo Chen, Yulin Liu

Article Number: 716 Published online on: 08 August 2021
Article Open Access
Article Open Access

SPP1 and FN1 are significant gene biomarkers of tongue squamous cell carcinoma

Xiao-Liang Xu, Hui Liu, Ying Zhang, Su-Xin Zhang, Zhong Chen, Yang Bao, Tian-Ke Li

Article Number: 713 Published online on: 06 August 2021
Article

FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang

Article Number: 712 Published online on: 05 August 2021
Article Open Access

RNA m6A methyltransferase METTL3 promotes colorectal cancer cell proliferation and invasion by regulating Snail expression

Jianfan Wen, Guowei Zhang, Yuwen Meng, Lei Zhang, Min Jiang, Zhitao Yu

Article Number: 711 Published online on: 05 August 2021
Article Open Access

Overexpression of E74‑like transformation‑specific transcription factor 3 promotes cellular proliferation and predicts poor prognosis in ovarian cancer

Yao Liu, Shourong Wang, Ruiqi Zhou, Wenxue Li, Guiyu Zhang

Article Number: 710 Published online on: 05 August 2021
Article Open Access

Association between miR‑212‑3p and SOX11, and the effects of miR‑212‑3p on cell proliferation and migration in mantle cell lymphoma

Yuyang Tian, Li Wang, Yanming Zhang, Lianqiao Li, Yingying Fei, Xingxia Zhang, Guoqiang Lin

Article Number: 709 Published online on: 05 August 2021
Article Open Access

Small heterodimer partner as a predictor of neoadjuvant radiochemotherapy response and survival in patients with rectal cancer: A preliminary study

Sup Kim, Mina Joo, Min-Kyung Yeo, Moon-June Cho, Jun-Sang Kim, Eun-Kyeong Jo, Jin-Man Kim

Article Number: 708 Published online on: 04 August 2021
Article Open Access

Effect and mechanism of action of SLP‑2 on the apoptosis and autophagy of gastric cancer cells

Shengsen Yang, Yun Huang, Hongyan Zhang, Fang Wang, Liangui Shao, Xuehong Wang

Article Number: 707 Published online on: 04 August 2021
Article Open Access

Proteome profiling of formalin‑fixed, paraffin‑embedded lung adenocarcinoma tissues using a tandem mass tag‑based quantitative proteomics approach

Qi Xie, Dan Wang, Xiao Luo, Zhen Li, Aixia Hu, Hui Yang, Jinxing Tang, Peiyu Gao, Tingyi Sun, Lingfei Kong

Article Number: 706 Published online on: 04 August 2021
Article Open Access

Role of JNK activation in paclitaxel‑induced apoptosis in human head and neck squamous cell carcinoma

Yu-Yan Lan, Ying-Hui Chen, Cheng Liu, Kuo-Lung Tung, Yen-Ting Wu, Sheng-Chieh Lin, Chin-Han Wu, Hong-Yi Chang, Yung-Chia Chen, Bu-Miin Huang

Article Number: 705 Published online on: 03 August 2021
Article Open Access

Circ_0074027 binds to EIF4A3 and promotes gastric cancer progression

Yuluo Wu, Haiyang Zhao

Article Number: 704 Published online on: 03 August 2021
Article Open Access

Photosensitizer verteporfin inhibits the growth of YAP‑ and TAZ‑dominant gastric cancer cells by suppressing the anti‑apoptotic protein Survivin in a light‑independent manner

Takashi Hasegawa, Takaaki Sugihara, Yoshiki Hoshino, Ryohei Tarumoto, Yukako Matsuki, Tsutomu Kanda, Tomoaki Takata, Takakazu Nagahara, Tomomitsu Matono, Hajime Isomoto

Article Number: 703 Published online on: 03 August 2021
Article Open Access

Characterization of tumor‑associated MUC1 and its glycans expressed in mucoepidermoid carcinoma

Eisaku Isaka, Takanori Sugiura, Kazuhiko Hashimoto, Kazutaka Kikuta, Ukei Anazawa, Takeshi Nomura, Akihiko Kameyama

Article Number: 702 Published online on: 03 August 2021
Article Open Access

Lymphomatosis cerebri: Multimodality imaging features and misdiagnosis analysis

Zhibing Ruan, Lan Chu, Chunfeng Liu, Yu Hu, Jinjin Huang

Article Number: 701 Published online on: 03 August 2021
Article Open Access

Combination of nigericin with cisplatin enhances the inhibitory effect of cisplatin on epithelial ovarian cancer metastasis by inhibiting slug expression via the Wnt/β‑catenin signalling pathway

Bin Zhou, Changlin Wang, Xiaobei Liu, Bin Wu, Jianwei Li, Shujuan Yao, Shiqian Zhang

Article Number: 700 Published online on: 03 August 2021
Retraction Open Access

[Retracted] microRNA‑23a promotes cell growth and metastasis in gastric cancer via targeting SPRY2‑mediated ERK signaling

Yingjia Li, Hui Chen, Pengfei She, Ti Chen, Lihua Chen, Jinling Yuan, Botao Jiang

Article Number: 699 Published online on: 02 August 2021
Correction Open Access

[Corrigendum] lncRNA HAR1B has potential to be a predictive marker for pazopanib therapy in patients with sarcoma

Hideharu Yamada, Masanobu Takahashi, Munenori Watanuki, Mika Watanabe, Sakura Hiraide, Ken Saijo, Keigo Komine, Chikashi Ishioka

Article Number: 698 Published online on: 02 August 2021
Article Open Access

A micro‑peptide encoded by HOXB‑AS3 promotes the proliferation and viability of oral squamous cell carcinoma cell lines by directly binding with IGF2BP2 to stabilize c‑Myc

Fei Leng, Yan-Yu Miu, Yi Zhang, Hao Luo, Xiao-Li Lu, Hui Cheng, Zhi-Guo Zheng

Article Number: 697 Published online on: 02 August 2021
Article Open Access

miR‑425 regulates lipophagy via SIRT1 to promote sorafenib resistance in liver cancer

Gongping Sun, Liang Yang, Shibo Wei, Hongyuan Jin, Bowen Li, Hangyu Li

Article Number: 695 Published online on: 02 August 2021
Article
Article Open Access

Identification of differentially expressed genes using microarray analysis and COL6A1 induction of bone metastasis in non‑small cell lung cancer

Nan Li, Ming Liu, Xiaohui Cao, Wei Li, Yunfang Li, Zongmao Zhao

Article Number: 693 Published online on: 01 August 2021
Article Open Access

Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG‑1 human acute myeloid leukemia cell line and its mechanism

Ping He, Jian Lei, Li-Xin Zou, Gui-Zhen Zhou, Lang Peng, Qian Deng, Xiao-Liu Liu

Article Number: 692 Published online on: 01 August 2021
Article Open Access

Penicillin disrupts mitochondrial function and induces autophagy in colorectal cancer cell lines

Fei Hu, Yu Wu, Cheng Liu, Yingchao Zhu, Shazhou Ye, Yang Xi, Wei Cui, Shizhong Bu

Article Number: 691 Published online on: 01 August 2021
Article Open Access

Examination of the differences between sulforaphane and sulforaphene in colon cancer: A study based on next‑generation sequencing

Lei Gao, Fengying Du, Jinshen Wang, Yuhua Zhao, Junhua Liu, Da Cai, Xiao Zhang, Yutao Wang, Shuqiu Zhang

Article Number: 690 Published online on: 01 August 2021
Article Open Access

Novel bone microenvironment model of castration‑resistant prostate cancer with chitosan fiber matrix and osteoblasts

Masahiro Samoto, Hideyasu Matsuyama, Hiroaki Matsumoto, Hiroshi Hirata, Koji Ueno, Sho Ozawa, Junichi Mori, Ryo Inoue, Seiji Yano, Yoshiaki Yamamoto, Jun Haginaka, Shizuyo Horiyama, Koji Tamada

Article Number: 689 Published online on: 01 August 2021
Article Open Access

Dihydroartemisinin suppresses proliferation, migration, the Wnt/β‑catenin pathway and EMT via TNKS in gastric cancer Corrigendum in /10.3892/ol.2021.13152

Yanmei Ma, Peng Zhang, Qilong Zhang, Xiaofei Wang, Qiong Miao, Xiaolan Lyu, Bo Cui, Honghong Ma

Article Number: 688 Published online on: 29 July 2021
Journal Cover

October-2021
Volume 22 Issue 4

Print ISSN: 1792-1074
Online ISSN: 1792-1082

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