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September-2022 Volume 24 Issue 3

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Case Report Open Access

Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report

  • Authors:
    • Junjie Yang
    • Hongsheng Liu
    • Bin Huang
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, The First People's Hospital of Xiaoshan District, Hangzhou, Zhejiang 311200, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 322
    |
    Published online on: July 20, 2022
       https://doi.org/10.3892/ol.2022.13442
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Abstract

Primary retroperitoneal perirenal CIC rearrangement sarcoma is rare. The current case report presents a 69‑year‑old male patient with this pathology, including the clinical features, pathomorphology and immunohistochemistry, and CIC gene rupture detected by fluorescence in situ hybridization (FISH). Furthermore, the relevant literature was reviewed. Histologically, the tumor was composed of diffuse nests of small‑ to medium‑sized juvenile round blue cells with hyperchromatic nuclei, prominent nucleoli and occasional mitotic signs. The tumor involved adipose tissue with no obvious hemorrhagic necrotic foci. Immunohistochemistry indicated scattered expression of CD99 in tumor cells. FISH examination suggested that the CIC gene was fragmented and translocated.
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Copy and paste a formatted citation
Spandidos Publications style
Yang J, Liu H and Huang B: Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncol Lett 24: 322, 2022.
APA
Yang, J., Liu, H., & Huang, B. (2022). Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncology Letters, 24, 322. https://doi.org/10.3892/ol.2022.13442
MLA
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24.3 (2022): 322.
Chicago
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24, no. 3 (2022): 322. https://doi.org/10.3892/ol.2022.13442
Copy and paste a formatted citation
x
Spandidos Publications style
Yang J, Liu H and Huang B: Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncol Lett 24: 322, 2022.
APA
Yang, J., Liu, H., & Huang, B. (2022). Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncology Letters, 24, 322. https://doi.org/10.3892/ol.2022.13442
MLA
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24.3 (2022): 322.
Chicago
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24, no. 3 (2022): 322. https://doi.org/10.3892/ol.2022.13442
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