Open Access

Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report

  • Authors:
    • Junjie Yang
    • Hongsheng Liu
    • Bin Huang
  • View Affiliations

  • Published online on: July 20, 2022     https://doi.org/10.3892/ol.2022.13442
  • Article Number: 322
  • Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Primary retroperitoneal perirenal CIC rearrangement sarcoma is rare. The current case report presents a 69‑year‑old male patient with this pathology, including the clinical features, pathomorphology and immunohistochemistry, and CIC gene rupture detected by fluorescence in situ hybridization (FISH). Furthermore, the relevant literature was reviewed. Histologically, the tumor was composed of diffuse nests of small‑ to medium‑sized juvenile round blue cells with hyperchromatic nuclei, prominent nucleoli and occasional mitotic signs. The tumor involved adipose tissue with no obvious hemorrhagic necrotic foci. Immunohistochemistry indicated scattered expression of CD99 in tumor cells. FISH examination suggested that the CIC gene was fragmented and translocated.
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September-2022
Volume 24 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

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Copy and paste a formatted citation
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Spandidos Publications style
Yang J, Liu H and Huang B: Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncol Lett 24: 322, 2022
APA
Yang, J., Liu, H., & Huang, B. (2022). Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report. Oncology Letters, 24, 322. https://doi.org/10.3892/ol.2022.13442
MLA
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24.3 (2022): 322.
Chicago
Yang, J., Liu, H., Huang, B."Primary retroperitoneal perirenal CIC rearrangement sarcoma: A case report". Oncology Letters 24, no. 3 (2022): 322. https://doi.org/10.3892/ol.2022.13442