Open Access

Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report

  • Authors:
    • Andrea Vucetic
    • Belal Ahmad
    • Terence Tang
  • View Affiliations

  • Published online on: August 9, 2022     https://doi.org/10.3892/ol.2022.13454
  • Article Number: 335
  • Copyright: © Vucetic et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

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Abstract

Intracranial recurrence following initial cranial irradiation for extensive‑stage small cell lung cancer (ES‑SCLC) can often be a treatment dilemma given the aggressive nature of the disease, the overall poor prognosis and concerns regarding re‑treatment toxicity. The present report describes the case of a 62‑year‑old man diagnosed with ES‑SCLC and synchronous brain metastases who initially underwent whole brain radiotherapy, chemotherapy and consolidative thoracic radiotherapy. The patient was found to have a solitary intracranial recurrence at both 3.5 and 6 years after his diagnosis. On both occasions, the patient received salvage stereotactic radiation, 30 Gy in 5 fractions, and continues to remain functionally independent. Overall, the present case demonstrates that with the appropriate patient selection, aggressive local salvage of recurrent intracranial ES‑SCLC with stereotactic radiation can yield excellent and durable clinical outcomes.
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October-2022
Volume 24 Issue 4

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Spandidos Publications style
Vucetic A, Ahmad B and Tang T: Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report. Oncol Lett 24: 335, 2022
APA
Vucetic, A., Ahmad, B., & Tang, T. (2022). Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report. Oncology Letters, 24, 335. https://doi.org/10.3892/ol.2022.13454
MLA
Vucetic, A., Ahmad, B., Tang, T."Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report". Oncology Letters 24.4 (2022): 335.
Chicago
Vucetic, A., Ahmad, B., Tang, T."Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report". Oncology Letters 24, no. 4 (2022): 335. https://doi.org/10.3892/ol.2022.13454