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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2022 Volume 24 Issue 4

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

ISG15 is associated with cervical cancer development

Pingping Tao, Liyan Sun, Yanmei Sun, Yuhua Wang, Yumei Yang, Binlie Yang, Fang Li
Article Number: 380
Published online on: 12 September 2022

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Article Open Access

miR‑29a‑3p inhibits the malignant characteristics of non‑small cell lung cancer cells by reducing the activity of the Wnt/β‑catenin signaling pathway

Kang Zhang, Xiaoliang Han, Wenbin Hu, Chao Su, Binjun He
Article Number: 379
Published online on: 12 September 2022

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Article Open Access

A model for the early identification of sentinel lymph node metastasis in patients with breast cancer based on contrast‑enhanced ultrasound and clinical features

Juan Xu, Junzhi Li
Article Number: 378
Published online on: 08 September 2022

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Article Open Access

miR‑5590‑3p inhibits the proliferation and metastasis of renal cancer cells by targeting ROCK2 to inhibit proliferation, migration and invasion

Queling Liu, Anyi Zhu, Weiyin Gao, Fu Gui, Yan Zou, Xiaocheng Zhou, Zhengdong Hong
Article Number: 377
Published online on: 08 September 2022

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Article Open Access

Cancer‑associated gene analysis of cervical cytology samples and liquid‑based cytology significantly improve endometrial cancer diagnosis sensitivity

Ryo Nimura, Eiji Kondo, Kenta Yoshida, Michiko Kubo-Kaneda, Masafumi Nii, Makoto Ikeijiri, Maki Nakamura, Hiroshi Imai, Yoshinaga Okugawa, Kaname Nakatani, Tomoaki Ikeda
Article Number: 376
Published online on: 08 September 2022

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Article Open Access

Prognostic significance of sarcopenia as determined by bioelectrical impedance analysis in patients with advanced pancreatic cancer receiving gemcitabine plus nab‑paclitaxel: A retrospective study

Yuichiro Tozuka, Makoto Ueno, Satoshi Kobayashi, Manabu Morimoto, Taito Fukushima, Yusuke Sano, Kuniyuki Kawano, Akane Hanaoka, Shun Tezuka, Hiroyuki Asama, Satoshi Moriya, Soichiro Morinaga, Shinichi Ohkawa, Shin Maeda
Article Number: 375
Published online on: 08 September 2022

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Article Open Access

Cyclin genes as potential novel prognostic biomarkers and therapeutic targets in breast cancer

Nian-Qiu Liu, Wei-Han Cao, Xing Wang, Junyao Chen, Jianyun Nie
Article Number: 374
Published online on: 05 September 2022

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Article Open Access

Prognostic implications of immune classification using IDO1 expression in extrahepatic bile duct carcinoma

Byeong-Joo Noh, Gun Moo Choi, Hyuk Jai Jang, Chung Hyeun Ma, Ho-Suk Oh, Moonho Kim, Dae-Woon Eom
Article Number: 373
Published online on: 05 September 2022

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Review Open Access

Emerging role of circRNAs in cancer under hypoxia (Review)

Qun Lai, Wenqiang Li, Hongping Wang, Siran Xu, Zhiping Deng
Article Number: 372
Published online on: 05 September 2022

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Article Open Access

Role of STX6 as a prognostic factor associated with immune infiltration in hepatocellular carcinoma

Yang Zhang, Leyan Li, Yi Tu, Zongfeng Feng, Yong Li, Jianbo Xiong
Article Number: 371
Published online on: 05 September 2022

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Case Report Open Access

Contrast‑enhanced ultrasound of ovarian steroid cell tumor, not otherwise specified: A case report

Mai Sun, Bo Zhang
Article Number: 370
Published online on: 05 September 2022

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Review Open Access

Immunosuppressive effects of vascular endothelial growth factor (Review)

Domenico Ribatti
Article Number: 369
Published online on: 01 September 2022

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Article Open Access

Feasibility and safety of platinum‑doublet therapy in patients with small‑cell lung cancer in the third‑line setting:
A multi‑institutional retrospective study

Takashi Fukushima, Tomonori Makiguchi, Yusuke Tanaka, Kei Chubachi, Mina Ishidoya, Sachio Suzuki, Hisashi Tanaka, Kageaki Taima, Yukihiro Hasegawa, Koichi Okudera, Sadatomo Tasaka
Article Number: 368
Published online on: 01 September 2022

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Article Open Access

Six autoantibodies as potential differential biomarkers of hepatocellular carcinoma vs. liver cirrhosis and chronic hepatitis: A prospective multi‑institutional study

Rei Okada, Yuichiro Otsuka, Osamu Yokosuka, Naoya Kato, Fumio Imazaki, Isamu Hoshino, Nobuyuki Sugiura, Hideaki Mizumoto, Ryousaku Azemoto, Kazuki Kato, Hideaki Shimada
Article Number: 367
Published online on: 31 August 2022

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Article Open Access

Comparative effectiveness of interventional therapeutic modalities for unresectable hepatocellular carcinoma: A systematic review and network meta‑analysis

Xin‑Long Chen, Hai‑Chuan Yu, Qi‑Gang Fan, Qi Yuan, Wen‑Kai Jiang, Shao‑Zhen Rui, Wen-Ce Zhou
Article Number: 366
Published online on: 31 August 2022

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Article

KDM5B expression in cisplatin resistant neuroblastoma cell lines

Marie Belhajova, Natalia Podhorska, Ales Vicha, Tomas Eckschlager
Article Number: 365
Published online on: 31 August 2022

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Article Open Access

Clinicopathological characteristics predicting advanced stage and surgical margin invasion of oral squamous cell carcinoma: A single‑center study on 10 years of cancer registry data

Nur Rahadiani, Muhammad Habiburrahman, Diah Rini Handjari, Marini Stephanie, Ening Krisnuhoni
Article Number: 364
Published online on: 31 August 2022

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Article Open Access

Inter‑component immunohistochemical assessment of proliferative markers in uterine carcinosarcoma

Andrzej Pyra, Aneta Adamiak‑Godlewska, Dorota Lewkowicz, Beata Bałon, Marek Cybulski, Anna Semczuk‑Sikora, Andrzej Semczuk
Article Number: 363
Published online on: 31 August 2022

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Article Open Access

Age does matter in adolescents and young adults vs. older adults with lung adenocarcinoma: A retrospective analysis comparing clinical characteristics and outcomes in response to systematic treatments

Lin Zhou, Huiwu Li, Shuhui Yang
Article Number: 362
Published online on: 31 August 2022

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Article Open Access

Influence of anesthetic technique on survival after tumor debulking surgery of elderly patients with ovarian cancer:
Results of a retrospective cohort study

Katharina Anic, Mona Wanda Schmidt, Annika Droste, Roxana Schwab, Marcus Schmidt, Slavomir Krajnak, Miriam Renz, Erik Kristoffer Hartmann, Roland Hardt, Annette Hasenburg, Marco Johannes Battista
Article Number: 361
Published online on: 26 August 2022

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Retraction Open Access

[Retracted] MicroRNA‑302a inhibits osteosarcoma cell migration and invasion by directly targeting IGF‑1R

Chunhong Zhang, Guomin Song, Weisheng Ye, Baoshan Xu
Article Number: 360
Published online on: 26 August 2022

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Article Open Access

Norcantharidin induces ferroptosis via the suppression of NRF2/HO‑1 signaling in ovarian cancer cells Retraction in /10.3892/ol.2025.14861

Xiaoyan Zhu, Xiaohong Chen, Longshan Qiu, Jianhua Zhu, Jiancai Wang
Article Number: 359
Published online on: 25 August 2022

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Review Open Access

Current progress in CAR‑T cell therapy for tumor treatment (Review)

Lei Chen, Ting Xie, Bing Wei, Da-Lin Di
Article Number: 358
Published online on: 25 August 2022

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Article Open Access

Predictors of treatment failure for adenocarcinoma in situ of the uterine cervix: Up to 14 years of recorded follow‑up

Karen Belkić, Sonia Andersson, Susanna Alder, Miriam Mints, David Megyessi
Article Number: 357
Published online on: 25 August 2022

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Article Open Access

Tumor‑associated macrophage‑derived exosomes promote EGFR‑TKI resistance in non‑small cell lung cancer by regulating the AKT, ERK1/2 and STAT3 signaling pathways

Shiyang Yuan, Wenjun Chen, Jian Yang, Yuanhai Zheng, Wen Ye, Hui Xie, Lie Dong, Junping Xie
Article Number: 356
Published online on: 24 August 2022

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Article Open Access

Sarcopenia does not predict outcome in patients with CNS lymphoma undergoing systemic therapy

Vincenzo Ferraro, Maximilian Thormann, Mattes Hinnerichs, Maciej Pech, Denise Wolleschak, Dimitrios Mougiakakos, Andreas Wienke, Alexandra Strobel, Vanja Zeremski, Alexey Surov, Jazan Omari
Article Number: 355
Published online on: 22 August 2022

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Article Open Access

CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism Corrigendum in /10.3892/ol.2026.15615

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 354
Published online on: 22 August 2022

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Article Open Access

Local recurrence for phyllodes tumours of the breast: Systematic review and meta‑analysis

Ioannis Boutas, Adamandia Kontogeorgi, Dionysios Dimas, Nektarios Koufopoulos, Sofia-Maria Genitsaridi, Kyparissia Sitara, Sophia Kalantaridou, Constantine Dimitrakakis
Article Number: 353
Published online on: 22 August 2022

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Case Report Open Access

Craniopharyngioma resection and aneurysm clipping performed simultaneously by pure endoscopic endonasal approach: A case report and literature review

Mingchao Zhang, Jian Wen Liao, Jingyang Chi, Huan Yu, Jianmin Kang
Article Number: 352
Published online on: 22 August 2022

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Article Open Access

Comprehensive bioinformatics analysis of the E2F family in human clear cell renal cell carcinoma

Zhi-Guo Liu, Jing Su, Hao Liu, Xue-Jian Yang, Xue Yang, Ye Wei, Xin-Yao Zhu, Yong Song, Xian-Cheng Zhao, Hong-Lin Guo
Article Number: 351
Published online on: 19 August 2022

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Case Report Open Access

Pulmonary thromboembolic disease or pulmonary artery intimal sarcoma: Case report and literature review

Nan Shao, Chaosheng Deng
Article Number: 350
Published online on: 19 August 2022

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Review

Roles of ABCA1 in cancer (Review)

Kun Wu, Longwei Zou, Xiaoyong Lei, Xiaoyan Yang
Article Number: 349
Published online on: 19 August 2022

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Article Open Access

Associations of C‑X‑C motif chemokine ligands 1/2/8/13/14 with clinicopathological features and survival profile in patients with colorectal cancer

Xiaofan Luo, Jiandong Tai, Yuhang Zhao, Pingwei Zhao, Di Sun, Lei Wang
Article Number: 348
Published online on: 18 August 2022

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Article Open Access

Lidocaine inhibits the proliferation and migration of endometrial cancer cells, and promotes apoptosis by inducing autophagy

Dingde Long, Yayu Chen, Liangchao Qu, Yang Dong
Article Number: 347
Published online on: 17 August 2022

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Article Open Access

RNA binding protein PUM2 promotes hepatocellular carcinoma proliferation and apoptosis via binding to the 3'UTR of BTG3

Zhenhua Liu, Chunye Lv
Article Number: 346
Published online on: 17 August 2022

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Article Open Access

Effect of bacterium in the malignant wounds of soft tissue sarcoma

Eiji Nakata, Tomohiro Fujiwara, Haruyoshi Katayama, Takuto Itano, Toshiyuki Kunisada, Toshifumi Ozaki
Article Number: 345
Published online on: 17 August 2022

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Case Report Open Access

Metastatic ovarian tumor from pancreatic cancer treated with combined immunotherapy: A case report

Yiying Tao, Lei Tang, Li Zuo, Yue Ma, Fengchun Zhang, Yingchun Xu
Article Number: 344
Published online on: 17 August 2022

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Case Report Open Access

Synchronal pulmonary sarcomatoid carcinoma and lung adenocarcinoma EML4‑ALK fusion: A case report

Mingting Wang, Yifan Gong, Yun Cheng, Lei Yang, Wenhui Wang, Xiaolin Lei
Article Number: 343
Published online on: 17 August 2022

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Retraction Open Access

[Retracted] miR‑150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1

Chang-Hui Li, Teng-Bo Yu, Hong-Wei Qiu, Xia Zhao, Chuan-Li Zhou, Chao Qi
Article Number: 342
Published online on: 17 August 2022

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Article Open Access

Radiological classification of meningiomas with hemorrhagic onset and its clinical significance

Zuo-Run Xie, Hong-Cai Wang, Yi-Lei Tong, Shi-Wei Li, Mao-Song Chen, Bo-Ding Wang
Article Number: 341
Published online on: 12 August 2022

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Article Open Access

ABO blood classification and the risk of lung cancer: A meta‑analysis and trial sequential analysis

Haotian Yang, Ziqi Tan, Yizhen Zhang, Jiaqi Sun, Peng Huang
Article Number: 340
Published online on: 12 August 2022

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Case Report Open Access

Long‑term remission under Disitamab Vedotin (RC48) in HR‑positive/HER2‑positive metastatic breast cancer with brain meningeal, and bone marrow involvement: A case report

Qifeng Wu, Lina He, Jing Luo, Wen Jin, Yingchun Xu, Chen Wang
Article Number: 339
Published online on: 12 August 2022

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Article

Tumor‑treating fields in combination with sorafenib restrain the proliferation of liver cancer in vitro

Yoonjung Jang, Won Seok Lee, Sei Sai, Jeong Yub Kim, Jong-Ki Kim, Eun Ho Kim
Article Number: 338
Published online on: 11 August 2022

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Article Open Access

Clinical impact of remnant lymphatic invasion on the recurrence of esophageal squamous cell carcinoma after esophagectomy with neoadjuvant chemotherapy

Sho Okuda, Kenoki Ohuchida, Koji Shindo, Taiki Moriyama, Jun Kawata, Koji Tamura, Masafumi Sada, Kinuko Nagayoshi, Yusuke Mizuuchi, Naoki Ikenaga, Kohei Nakata, Yoshinao Oda, Masafumi Nakamura
Article Number: 337
Published online on: 11 August 2022

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Article Open Access

Immunoexpression of p62/SQSTM1/Sequestosome‑1 in human primary and recurrent IDH1/2 wild‑type glioblastoma: A pilot study

Antonio Ieni, Cristina Pizzimenti, Giuseppe Broggi, Rosario Caltabiano, Antonino Germanò, Giuseppe Maria Vincenzo Barbagallo, Paolo Vigneri, Giuseppe Giuffrè, Giovanni Tuccari
Article Number: 336
Published online on: 11 August 2022

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Case Report Open Access

Long‑term survival in a patient with extensive‑stage small cell lung cancer treated with multiple courses of salvage stereotactic radiation after whole brain radiotherapy: A case report

Andrea Vucetic, Belal Ahmad, Terence Tang
Article Number: 335
Published online on: 09 August 2022

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Article Open Access

tRNA‑derived fragment tRF‑Glu49 inhibits cell proliferation, migration and invasion in cervical cancer by targeting FGL1 Retraction in /10.3892/ol.2025.15150

Yang Wang, Wenying Xia, Fangrong Shen, Jinhua Zhou, Yanzheng Gu, Youguo Chen
Article Number: 334
Published online on: 09 August 2022

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Article Open Access

Androgen receptor axis‑targeted agents are not superior to conventional hormonal therapy for treatment of metastatic prostate cancer

Akinori Wada, Mitsuhiro Narita, Masayuki Nagasawa, Takuto Kusaba, Shigehisa Kubota, Tetsuya Yoshida, Kazuyoshi Johnin, Akihiro Kawauchi, Susumu Kageyama
Article Number: 333
Published online on: 09 August 2022

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Article Open Access

Efficacy of a combined tool for stage I non‑small cell lung cancer against lymph node metastasis

Takeo Nakada, Mitsuo Yabe, Takashi Ohtsuka
Article Number: 332
Published online on: 09 August 2022

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Article Open Access

Impact on breast cancer susceptibility and clinicopathological traits of common genetic polymorphisms in TP53, MDM2 and ATM genes in Sardinian women

Matteo Floris, Giovanna Pira, Paolo Castiglia, Maria Laura Idda, Maristella Steri, Maria Rosaria De Miglio, Andrea Piana, Andrea Cossu, Antonio Azara, Caterina Arru, Giovanna Deiana, Carlo Putzu, Valeria Sanna, Ciriaco Carru, Antonello Serra, Marco Bisail, Maria Rosaria Muroni
Article Number: 331
Published online on: 08 August 2022

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Article Open Access

MicroRNA‑181b‑5p insufficiency predicts treatment response failure risk and unfavorable event‑free survival as well as overall survival in acute myeloid leukemia patients

Huina Lu, Yi Ding, Yan Dong, Xiu Luo, Xiuqin Wang, Bing Xiu, Aibin Liang, Wenjun Zhang
Article Number: 330
Published online on: 05 August 2022

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Article

S‑phase fraction, lymph node status and disease staging as the main prognostic factors to differentiate between young and older patients with invasive breast carcinoma

António E. Pinto, João Matos, Teresa Pereira, Giovani L. Silva, Saudade André
Article Number: 329
Published online on: 04 August 2022

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Article Open Access

Isolinderalactone inhibits glioblastoma cell supernatant‑induced angiogenesis

Seo-Yeon Lee, Jung Hwa Park, Kang-Hyun Cho, Huiseon Kim, Hwa Kyoung Shin
Article Number: 328
Published online on: 02 August 2022

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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