Retroperitoneal malignant solitary fibrous tumor with second recurrence and lymphatic metastases: A case report
- Lei Liu
- Shiqiang Chen
- Lihua Wang
Affiliations: Department of Pathology, Peking University International Hospital, Beijing 102206, P.R. China
- Published online on: December 20, 2022 https://doi.org/10.3892/ol.2022.13643
Copyright: © Liu
et al. This is an open access article distributed under the
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Commons Attribution License.
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Malignant solitary fibrous tumor (SFT) in the retroperitoneum is rare. The present study reported on the case of a 67‑year‑old man who had retroperitoneal SFT for ~13 years, which resulted in two recurrences and lymphatic metastases. After the second recurrence, the patient presented with hematochezia and multiple retroperitoneal masses were found through computed tomography (CT). Histopathological examination showed that the tumor was mainly comprised of short spindle cells, arranged into sparse and dense areas. Mitotic figures were observed, generally 6‑8 mitoses/10 high power fields, along with local necrosis. The tumor invaded the circumferential liver, intestines, lymphatic vessels and lymph nodes. Combined with the immunohistochemical results, it was diagnosed as a malignant SFT, which regrew just 2 months after the latest surgery. Retroperitoneal SFTs with repeated relapses, infiltrative growth and lymphatic metastasis suggest the need for careful and long‑term follow‑up.