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Case Report Open Access

Imaging of Merkel cell carcinoma of the eyelid: A case report

  • Authors:
    • Guangwen Zhu
    • Liting Xie
    • Xianwen Hu
  • View Affiliations / Copyright

    Affiliations: Department of Endocrinology, Zunyi Hospital of Traditional Chinese Medicine, Zunyi, Guizhou 563003, P.R. China, Department of Gynecology, Zunyi Hospital of Traditional Chinese Medicine, Zunyi, Guizhou 563000, P.R. China, Department of Nuclear Medicine, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China
    Copyright: © Zhu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 119
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    Published online on: January 23, 2024
       https://doi.org/10.3892/ol.2024.14252
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Abstract

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine carcinoma commonly found in older adults in areas of the skin that are susceptible to ultraviolet ray damage. The current study reports the case of a 79‑year‑old woman who presented to the Affiliated Hospital of Zunyi Medical University (Zunyi, China) with a painless lump in the lower eyelid of the left eye accompanied by photophobic tears for 4 months. Head computed tomography (CT) and magnetic resonance imaging (MRI) showed a space‑occupying lesion ~2.8x2.4 cm in size outside the left orbital muscle cone, which was poorly demarcated from the surrounding normal tissues. Markedly intense and tortuous walking vascular shadows were observed within the tumor tissues. Fluorine‑18‑fluorodeoxyglucose positron emission tomography (18F‑FDG PET)/CT revealed increased 18F‑FDG uptake in the corresponding lesions. Based on these imaging features, a malignant tumor was suspected. The patient subsequently underwent surgery. Postoperative pathology and immunohistochemistry revealed MCC. The clinical presentation of MCC is usually a painless soft‑tissue nodule or mass that grows rapidly over a short period and is flesh‑colored, bluish red or purple. A slightly hyperdense mass on CT, with equal T1‑weighted and slightly longer T2‑weighted MRI signals, and mild enhancement on contrast‑enhanced scans, accompanied by significantly enhanced distorted vascular shadows and increased 18F‑FDG uptake on PET/CT, are valuable in the diagnosis of eyelid MCC.
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Copy and paste a formatted citation
Spandidos Publications style
Zhu G, Xie L and Hu X: Imaging of Merkel cell carcinoma of the eyelid: A case report. Oncol Lett 27: 119, 2024.
APA
Zhu, G., Xie, L., & Hu, X. (2024). Imaging of Merkel cell carcinoma of the eyelid: A case report. Oncology Letters, 27, 119. https://doi.org/10.3892/ol.2024.14252
MLA
Zhu, G., Xie, L., Hu, X."Imaging of Merkel cell carcinoma of the eyelid: A case report". Oncology Letters 27.3 (2024): 119.
Chicago
Zhu, G., Xie, L., Hu, X."Imaging of Merkel cell carcinoma of the eyelid: A case report". Oncology Letters 27, no. 3 (2024): 119. https://doi.org/10.3892/ol.2024.14252
Copy and paste a formatted citation
x
Spandidos Publications style
Zhu G, Xie L and Hu X: Imaging of Merkel cell carcinoma of the eyelid: A case report. Oncol Lett 27: 119, 2024.
APA
Zhu, G., Xie, L., & Hu, X. (2024). Imaging of Merkel cell carcinoma of the eyelid: A case report. Oncology Letters, 27, 119. https://doi.org/10.3892/ol.2024.14252
MLA
Zhu, G., Xie, L., Hu, X."Imaging of Merkel cell carcinoma of the eyelid: A case report". Oncology Letters 27.3 (2024): 119.
Chicago
Zhu, G., Xie, L., Hu, X."Imaging of Merkel cell carcinoma of the eyelid: A case report". Oncology Letters 27, no. 3 (2024): 119. https://doi.org/10.3892/ol.2024.14252
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