Open Access

Predictive value of multiple imaging predictive models for spread through air spaces of lung adenocarcinoma: A systematic review and network meta‑analysis

  • Authors:
    • Cong Liu
    • Yu-Feng Wang
    • Peng Wang
    • Feng Guo
    • Hong-Ying Zhao
    • Qiang Wang
    • Zhi-Wei Shi
    • Xiao-Feng Li
  • View Affiliations

  • Published online on: January 25, 2024     https://doi.org/10.3892/ol.2024.14255
  • Article Number: 122
  • Copyright: © Liu et al. This is an open access article distributed under the terms of Creative Commons Attribution License.

Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

Spread Through Air Spaces (STAS) is involved in lung adenocarcinoma (LUAD) recurrence, where cancer cells spread into adjacent lung tissue, impacting surgical planning and prognosis assessment. Radiomics‑based models show promise in predicting STAS preoperatively, enhancing surgical precision and prognostic evaluations. The present study performed network meta‑analysis to assess the predictive efficacy of imaging models for STAS in LUAD. Data were systematically sourced from PubMed, Embase, Scopus, Wiley and Web of Science, according to the Cochrane Handbook for Systematic Reviews of Interventions) and A Measurement Tool to Assess systematic Reviews 2. Using Stata software v17.0 for meta‑analysis, surface under the cumulative ranking area (SUCRA) was applied to identify the most effective diagnostic method. Quality assessments were performed using Cochrane Collaboration's risk‑of‑bias tool and publication bias was assessed using Deeks' funnel plot. The analysis encompassed 14 articles, involving 3,734 patients, and assessed 17 predictive models for STAS in LUAD. According to comprehensive analysis of SUCRA, the machine learning (ML)_Peri_tumour model had the highest accuracy (56.5), the Features_computed tomography (CT) model had the highest sensitivity (51.9) and the positron emission tomography (pet)_CT model had the highest specificity (53.9). ML_Peri_tumour model had the highest predictive performance. The accuracy was as follows: ML_Peri_tumour vs. Features_CT [relative risk (RR)=1.14; 95% confidence interval (CI), 0.99‑1.32]; ML_Peri_tumour vs. ML_Tumour (RR=1.04; 95% CI, 0.83‑1.30) and ML_Peri_tumour vs. pet_CT (RR=1.04; 95% CI, 0.84‑1.29). Comparative analyses revealed heightened predictive accuracy of the ML_Peri_tumour compared with other models. Nonetheless, the field of radiological feature analysis for STAS prediction remains nascent, necessitating improvements in technical reproducibility and comprehensive model evaluation.
View Figures
View References

Related Articles

Journal Cover

March-2024
Volume 27 Issue 3

Print ISSN: 1792-1074
Online ISSN:1792-1082

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
Liu C, Wang Y, Wang P, Guo F, Zhao H, Wang Q, Shi Z and Li X: Predictive value of multiple imaging predictive models for spread through air spaces of lung adenocarcinoma: A systematic review and network meta‑analysis. Oncol Lett 27: 122, 2024.
APA
Liu, C., Wang, Y., Wang, P., Guo, F., Zhao, H., Wang, Q. ... Li, X. (2024). Predictive value of multiple imaging predictive models for spread through air spaces of lung adenocarcinoma: A systematic review and network meta‑analysis. Oncology Letters, 27, 122. https://doi.org/10.3892/ol.2024.14255
MLA
Liu, C., Wang, Y., Wang, P., Guo, F., Zhao, H., Wang, Q., Shi, Z., Li, X."Predictive value of multiple imaging predictive models for spread through air spaces of lung adenocarcinoma: A systematic review and network meta‑analysis". Oncology Letters 27.3 (2024): 122.
Chicago
Liu, C., Wang, Y., Wang, P., Guo, F., Zhao, H., Wang, Q., Shi, Z., Li, X."Predictive value of multiple imaging predictive models for spread through air spaces of lung adenocarcinoma: A systematic review and network meta‑analysis". Oncology Letters 27, no. 3 (2024): 122. https://doi.org/10.3892/ol.2024.14255