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Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project

  • Authors:
    • Rai Shimoyama
    • Yoshinori Imamura
    • Kiyoaki Uryu
    • Takahiro Mase
    • Megumi Shiragami
    • Yoshiaki Fujimura
    • Maki Hayashi
    • Megu Ohtaki
    • Keiko Ohtani
    • Nobuaki Shinozaki
    • Hironobu Minami
  • View Affiliations / Copyright

    Affiliations: Department of General Surgery, Shonan Kamakura General Hospital, Kamakura, Kanagawa 247‑8533, Japan, Department of Medical Oncology and Hematology, Kobe University Graduate School of Medicine, Kobe, Hyogo 650‑0017, Japan, Department of Medical Oncology, Yao Tokushukai General Hospital, Osaka 581‑0011, Japan, Department of Breast Surgery, Ogaki Tokushukai Hospital, Ogaki, Gifu 503‑0015, Japan, Tokushukai Information System, Inc., Osaka 530‑0001, Japan, Mirai Iryo Research Center Inc., Tokyo 102‑0074, Japan, deCult Co., Ltd., Hatsukaichi, Hiroshima 739‑0413, Japan
    Copyright: © Shimoyama et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 136
    |
    Published online on: January 31, 2024
       https://doi.org/10.3892/ol.2024.14269
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Abstract

Inflammation‑based prognostic markers based on a combination of blood‑based parameters, including the modified Glasgow prognostic score (mGPS), have been associated with clinical outcomes in patients with various types of cancer. The present study aimed to evaluate and compare the accuracy of these previously reported markers in patients with metastatic pancreatic cancer receiving first‑line chemotherapy. A total of 846 patients were identified between April 2010 and March 2020 as part of a nationwide real‑world study from 46 Tokushukai medical group hospitals in Japan. Blood laboratory data collected within 14 days of starting first‑line chemotherapy assessed 17 inflammation‑based prognostic markers. Information from patients with no missing data was used to compare the accuracy and performance of the inflammation‑based prognostic markers. A total of 487 patients were eligible for this supplemental analysis. The 17 inflammation‑based markers demonstrated significant prognostic value. Among them, the concordance rate with overall survival (OS) was highest for mGPS. The median OS time of patients with mGPS 0, 1 and 2 was 8.2, 6.0 and 2.9 months, respectively. Compared with mGPS 0, mGPS 1 and 2 showed hazard ratios of 1.39 (95% confidence interval, 1.07‑1.81) and 2.63 (2.00‑3.45), respectively. The present real‑world data analysis showed that various previously reported inflammation‑based markers had significant prognostic value in patients with metastatic pancreatic cancer. Among these markers, the mGPS demonstrated the highest level of accuracy. This trial has been registered in the University Hospital Medical Information Network Clinical Trials Registry as UMIN000050590 on April 1, 2023.
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Figure 1

View References

1 

Siegel RL, Miller KD, Fuchs HE and Jemal A: Cancer statistics, 2021. CA Cancer J Clin. 71:7–33. 2021. View Article : Google Scholar : PubMed/NCBI

2 

SEER 5-year relative survival rate, 2012–2018, . Cancer Statistics Explorer Network. National Cancer Institute; United States: https://seer.cancer.gov/statistics-network/explorer/application.htmlApril 1–2023

3 

Cancer Information Service, National Cancer Center, Japan and National Cancer Registry (In Japanese) (Ministry of Health, Labour and Welfare), . https://ganjoho.jp/reg_stat/statistics/data/dl/en.htmlApril 1–2023

4 

Conroy T, Desseigne F, Ychou M, Bouché O, Guimbaud R, Bécouarn Y, Adenis A, Raoul JL, Gourgou-Bourgade S, de la Fouchardière C, et al: FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med. 364:1817–1825. 2011. View Article : Google Scholar : PubMed/NCBI

5 

Okusaka T, Ikeda M, Fukutomi A, Ioka T, Furuse J, Ohkawa S, Isayama H and Boku N: Phase II study of FOLFIRINOX for chemotherapy-naïve Japanese patients with metastatic pancreatic cancer. Cancer Sci. 105:1321–1326. 2014. View Article : Google Scholar : PubMed/NCBI

6 

Ozaka M, Ishii H, Sato T, Ueno M, Ikeda M, Uesugi K, Sata N, Miyashita K, Mizuno N, Tsuji K, et al: A phase II study of modified FOLFIRINOX for chemotherapy-naïve patients with metastatic pancreatic cancer. Cancer Chemother Pharmacol. 81:1017–1023. 2018. View Article : Google Scholar : PubMed/NCBI

7 

Von Hoff DD, Ervin T, Arena FP, Chiorean EG, Infante J, Moore M, Seay T, Tjulandin SA, Ma WW, Saleh MN, et al: Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med. 369:1691–1703. 2013. View Article : Google Scholar : PubMed/NCBI

8 

Shimoyama R, Imamura Y, Uryu K, Mase T, Fujimura Y, Hayashi M, Ohtaki M, Ohtani K, Shinozaki N and Minami H: Real-world treatment outcomes among patients with metastatic pancreatic cancer in Japan: The Tokushukai real-world data project. Mol Clin Oncol. 19:982023. View Article : Google Scholar : PubMed/NCBI

9 

McMillan DC: An inflammation-based prognostic score and its role in the nutrition-based management of patients with cancer. Proc Nutr Soc. 67:257–262. 2008. View Article : Google Scholar : PubMed/NCBI

10 

Buzby GP, Mullen JL, Matthews DC, Hobbs C and Rosato EF: Prognostic nutritional index in gastrointestinal surgery. Am J Surg. 139:160–167. 1980. View Article : Google Scholar : PubMed/NCBI

11 

McMillan DC: Systemic inflammation, nutritional status and survival in patients with cancer. Curr Opin Clin Nutr Metab Care. 12:223–226. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Dolan RD, McSorley ST, Horgan PG, Laird B and McMillan DC: The role of the systemic inflammatory response in predicting outcomes in patients with advanced inoperable cancer: Systematic review and meta-analysis. Crit Rev Oncol Hematol. 116:134–146. 2017. View Article : Google Scholar : PubMed/NCBI

13 

Shimoyama R, Imamura Y, Uryu K, Mase T, Fujimura Y, Hayashi M, Ohtaki M, Ohtani K, Shinozaki N and Minami H: Real-world outcomes of systemic therapy in Japanese patients with cancer (Tokushukai REAl-world data project: TREAD): Study protocol for a nationwide cohort study. Healthcare (Basel). 10:21462022. View Article : Google Scholar : PubMed/NCBI

14 

Eba J and Nakamura K: Overview of the ethical guidelines for medical and biological research involving human subjects in Japan. Jpn J Clin Oncol. 52:539–544. 2022. View Article : Google Scholar : PubMed/NCBI

15 

National Cancer Registry (Ministry of Health, Labour and Welfare), tabulated by Cancer Information Service, National Cancer Center, Japan, . https://ganjoho.jp/reg_stat/statistics/data/dl/en.htmlApril 1–2023

16 

Onodera T, Goseki N and Kosaki G: Prognostic nutritional index in gastrointestinal surgery of malnourished cancer patients. Nihon Geka Gakkai Zasshi. 85:1001–1005. 1984.(In Japanese). PubMed/NCBI

17 

Forrest LM, McMillan DC, McArdle CS, Angerson WJ and Dunlop DJ: Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer. Br J Cancer. 89:1028–1030. 2003. View Article : Google Scholar : PubMed/NCBI

18 

Fairclough E, Cairns E, Hamilton J and Kelly C: Evaluation of a modified early warning system for acute medical admissions and comparison with C-reactive protein/albumin ratio as a predictor of patient outcome. Clin Med (Lond). 9:30–33. 2009. View Article : Google Scholar : PubMed/NCBI

19 

Nakahara K, Monden Y, Ohno K, Fujii Y, Hashimoto J, Kitagawa Y and Kawashima Y: Importance of biologic status to the postoperative prognosis of patients with stage III nonsmall cell lung cancer. J Surg Oncol. 36:155–160. 1987. View Article : Google Scholar : PubMed/NCBI

20 

Smith RA, Bosonnet L, Raraty M, Sutton R, Neoptolemos JP, Campbell F and Ghaneh P: Preoperative platelet-lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma. Am J Surg. 197:466–472. 2009. View Article : Google Scholar : PubMed/NCBI

21 

Wilcox RA, Ristow K, Habermann TM, Inwards DJ, Micallef IN, Johnston PB, Colgan JP, Nowakowski GS, Ansell SM, Witzig TE, et al: The absolute monocyte and lymphocyte prognostic score predicts survival and identifies high-risk patients in diffuse large-B-cell lymphoma. Leukemia. 25:1502–1509. 2011. View Article : Google Scholar : PubMed/NCBI

22 

Proctor MJ, McMillan DC, Morrison DS, Fletcher CD, Horgan PG and Clarke SJ: A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer. Br J Cancer. 107:695–699. 2012. View Article : Google Scholar : PubMed/NCBI

23 

Watt DG, Proctor MJ, Park JH, Horgan PG and McMillan DC: The neutrophil-platelet score (NPS) predicts survival in primary operable colorectal cancer and a variety of common cancers. PLoS One. 10:e01421592015. View Article : Google Scholar : PubMed/NCBI

24 

Dolan RD, McSorley ST, Park JH, Watt DG, Roxburgh CS, Horgan PG and McMillan DC: The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores. Br J Cancer. 119:40–51. 2018. View Article : Google Scholar : PubMed/NCBI

25 

Dolan RD, Alwahid M, McSorley ST, Park JH, Stevenson RP, Roxburgh CS, Horgan PG and McMillan DC: A comparison of the prognostic value of composite ratios and cumulative scores in patients with operable rectal cancer. Sci Rep. 10:179652020. View Article : Google Scholar : PubMed/NCBI

26 

Kasymjanova G, MacDonald N, Agulnik JS, Cohen V, Pepe C, Kreisman H, Sharma R and Small D: The predictive value of pre-treatment inflammatory markers in advanced non-small-cell lung cancer. Curr Oncol. 17:52–58. 2010.PubMed/NCBI

27 

Qi Q, Zhuang L, Shen Y, Geng Y, Yu S, Chen H, Liu L, Meng Z, Wang P and Chen Z: A novel systemic inflammation response index (SIRI) for predicting the survival of patients with pancreatic cancer after chemotherapy. Cancer. 122:2158–2167. 2016. View Article : Google Scholar : PubMed/NCBI

28 

Mezquita L, Auclin E, Ferrara R, Charrier M, Remon J, Planchard D, Ponce S, Ares LP, Leroy L, Audigier-Valette C, et al: Association of the lung immune prognostic index with immune checkpoint inhibitor outcomes in patients with advanced non-small cell lung cancer. JAMA Oncol. 4:351–357. 2018. View Article : Google Scholar : PubMed/NCBI

29 

Müller L, Hahn F, Mähringer-Kunz A, Stoehr F, Gairing SJ, Michel M, Foerster F, Weinmann A, Galle PR, Mittler J, et al: Immunonutritive scoring for patients with hepatocellular carcinoma undergoing transarterial chemoembolization: Evaluation of the CALLY index. Cancers (Basel). 13:50182021. View Article : Google Scholar : PubMed/NCBI

30 

Forrest LM, McMillan DC, McArdle CS, Angerson WJ and Dunlop DJ: Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG) in patients receiving platinum-based chemotherapy for inoperable non-small-cell lung cancer. Br J Cancer. 90:1704–1706. 2004. View Article : Google Scholar : PubMed/NCBI

31 

McMillan DC, Crozier JEM, Canna K, Angerson WJ and McArdle CS: Evaluation of an inflammation-based prognostic score (GPS) in patients undergoing resection for colon and rectal cancer. Int J Colorectal Dis. 22:881–886. 2007. View Article : Google Scholar : PubMed/NCBI

32 

Toiyama Y, Miki C, Inoue Y, Tanaka K, Mohri Y and Kusunoki M: Evaluation of an inflammation-based prognostic score for the identification of patients requiring postoperative adjuvant chemotherapy for stage II colorectal cancer. Exp Ther Med. 2:95–101. 2011. View Article : Google Scholar : PubMed/NCBI

33 

Ferrucci PF, Ascierto PA, Pigozzo J, Del Vecchio M, Maio M, Antonini Cappellini GC, Guidoboni M, Queirolo P, Savoia P, Mandalà M, et al: Baseline neutrophils and derived neutrophil-to-lymphocyte ratio: Prognostic relevance in metastatic melanoma patients receiving ipilimumab. Ann Oncol. 27:732–738. 2016. View Article : Google Scholar : PubMed/NCBI

34 

Weide B, Martens A, Hassel JC, Berking C, Postow MA, Bisschop K, Simeone E, Mangana J, Schilling B, Di Giacomo AM, et al: Baseline biomarkers for outcome of melanoma patients treated with pembrolizumab. Clin Cancer Res. 22:5487–5496. 2016. View Article : Google Scholar : PubMed/NCBI

35 

Huang L, Han H, Zhou L, Chen X, Xu Q, Xie J, Zhan P, Chen S, Lv T and Song Y: Evaluation of the lung immune prognostic index in non-small cell lung cancer patients treated with systemic therapy: A retrospective study and meta-analysis. Front Oncol. 11:6702302021. View Article : Google Scholar : PubMed/NCBI

36 

Zhang Q, Gong X, Sun L, Miao L and Zhou Y: The predictive value of pretreatment lactate dehydrogenase and derived neutrophil-to-lymphocyte ratio in advanced non-small cell lung cancer patients treated with PD-1/PD-L1 inhibitors: A meta-analysis. Front Oncol. 12:7914962022. View Article : Google Scholar : PubMed/NCBI

37 

Banna GL, Di Quattro R, Malatino L, Fornarini G, Addeo A, Maruzzo M, Urzia V, Rundo F, Lipari H, De Giorgi U and Basso U: Neutrophil-to-lymphocyte ratio and lactate dehydrogenase as biomarkers for urothelial cancer treated with immunotherapy. Clin Transl Oncol. 22:2130–2135. 2020. View Article : Google Scholar : PubMed/NCBI

38 

Liu H, Yang XL, Yang XY, Dong ZR, Chen ZQ, Hong JG and Li T: The prediction potential of the pretreatment lung immune prognostic index for the therapeutic outcomes of immune checkpoint inhibitors in patients with solid cancer: A systematic review and meta-analysis. Front Oncol. 11:6910022021. View Article : Google Scholar : PubMed/NCBI

39 

Strijker M, van Veldhuisen E, van der Geest LG, Busch OR, Bijlsma MF, Mohammad NH, Homs MY, van Hooft JE, Verheij J, de Vos-Geelen J, et al: Readily available biomarkers predict poor survival in metastatic pancreatic cancer. Biomarkers. 26:325–334. 2021. View Article : Google Scholar : PubMed/NCBI

40 

Ahmad J, Grimes N, Farid S and Morris-Stiff G: Inflammatory response related scoring systems in assessing the prognosis of patients with pancreatic ductal adenocarcinoma: A systematic review. Hepatobiliary Pancreat Dis Int. 13:474–481. 2014. View Article : Google Scholar : PubMed/NCBI

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Copy and paste a formatted citation
Spandidos Publications style
Shimoyama R, Imamura Y, Uryu K, Mase T, Shiragami M, Fujimura Y, Hayashi M, Ohtaki M, Ohtani K, Shinozaki N, Shinozaki N, et al: Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project. Oncol Lett 27: 136, 2024.
APA
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y. ... Minami, H. (2024). Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project. Oncology Letters, 27, 136. https://doi.org/10.3892/ol.2024.14269
MLA
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y., Hayashi, M., Ohtaki, M., Ohtani, K., Shinozaki, N., Minami, H."Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project". Oncology Letters 27.3 (2024): 136.
Chicago
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y., Hayashi, M., Ohtaki, M., Ohtani, K., Shinozaki, N., Minami, H."Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project". Oncology Letters 27, no. 3 (2024): 136. https://doi.org/10.3892/ol.2024.14269
Copy and paste a formatted citation
x
Spandidos Publications style
Shimoyama R, Imamura Y, Uryu K, Mase T, Shiragami M, Fujimura Y, Hayashi M, Ohtaki M, Ohtani K, Shinozaki N, Shinozaki N, et al: Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project. Oncol Lett 27: 136, 2024.
APA
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y. ... Minami, H. (2024). Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project. Oncology Letters, 27, 136. https://doi.org/10.3892/ol.2024.14269
MLA
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y., Hayashi, M., Ohtaki, M., Ohtani, K., Shinozaki, N., Minami, H."Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project". Oncology Letters 27.3 (2024): 136.
Chicago
Shimoyama, R., Imamura, Y., Uryu, K., Mase, T., Shiragami, M., Fujimura, Y., Hayashi, M., Ohtaki, M., Ohtani, K., Shinozaki, N., Minami, H."Inflammation‑based prognostic markers of metastatic pancreatic cancer using real‑world data in Japan: The Tokushukai REAl‑world Data (TREAD) project". Oncology Letters 27, no. 3 (2024): 136. https://doi.org/10.3892/ol.2024.14269
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