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Gastric‑type endocervical adenocarcinoma: A report of two cases

  • Authors:
    • Qian Wang
    • Yanyu Li
    • Guangjuan Kan
    • Xiaofeng Fu
    • Minyan Wang
    • Jiang Zhu
  • View Affiliations / Copyright

    Affiliations: Department of Ultrasound Medicine, The First People's Hospital of Linhai City, Linhai, Zhejiang 317000, P.R. China, Department of Ultrasound Medicine, and State Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China, Department of Ultrasound Medicine, and State Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital School of Medicine Zhejiang University, Hangzhou, Zhejiang 310000, P.R. China
    Copyright: © Wang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 344
    |
    Published online on: May 30, 2024
       https://doi.org/10.3892/ol.2024.14477
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Abstract

Gastric‑type endocervical adenocarcinoma (GEA) is an uncommon and highly aggressive malignancy, characterized by non‑specific clinical manifestations. The limited number of documented cases poses significant challenges in achieving an early preoperative diagnosis. In the present study, two cases of GEA in female patients, aged 46 and 39 years, who presented with the chief complaint of profuse vaginal discharge are described. Both patients underwent a total hysterectomy and bilateral adnexectomy, leading to the definitive diagnosis of GEA through routine pathological and immunohistochemical examination. Following surgery, case one received conventional chemotherapy with paclitaxel and carboplatin, demonstrating no evidence of recurrence during a follow‑up period of >2 years. At present, patient B has been followed up for >1 year without any signs of disease recurrence. Given the rarity and diagnostic challenges associated with GEA, further investigations into its pathogenesis and diagnostic modalities are warranted. Additionally, due to its poor prognosis, close surveillance is essential for monitoring potential recurrences. Reporting such cases is crucial in aiding clinicians to make accurate diagnoses and treatment decisions.
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Copy and paste a formatted citation
Spandidos Publications style
Wang Q, Li Y, Kan G, Fu X, Wang M and Zhu J: Gastric‑type endocervical adenocarcinoma: A report of two cases. Oncol Lett 28: 344, 2024.
APA
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., & Zhu, J. (2024). Gastric‑type endocervical adenocarcinoma: A report of two cases. Oncology Letters, 28, 344. https://doi.org/10.3892/ol.2024.14477
MLA
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., Zhu, J."Gastric‑type endocervical adenocarcinoma: A report of two cases". Oncology Letters 28.2 (2024): 344.
Chicago
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., Zhu, J."Gastric‑type endocervical adenocarcinoma: A report of two cases". Oncology Letters 28, no. 2 (2024): 344. https://doi.org/10.3892/ol.2024.14477
Copy and paste a formatted citation
x
Spandidos Publications style
Wang Q, Li Y, Kan G, Fu X, Wang M and Zhu J: Gastric‑type endocervical adenocarcinoma: A report of two cases. Oncol Lett 28: 344, 2024.
APA
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., & Zhu, J. (2024). Gastric‑type endocervical adenocarcinoma: A report of two cases. Oncology Letters, 28, 344. https://doi.org/10.3892/ol.2024.14477
MLA
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., Zhu, J."Gastric‑type endocervical adenocarcinoma: A report of two cases". Oncology Letters 28.2 (2024): 344.
Chicago
Wang, Q., Li, Y., Kan, G., Fu, X., Wang, M., Zhu, J."Gastric‑type endocervical adenocarcinoma: A report of two cases". Oncology Letters 28, no. 2 (2024): 344. https://doi.org/10.3892/ol.2024.14477
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