Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
Oncology Letters
Join Editorial Board Propose a Special Issue
Print ISSN: 1792-1074 Online ISSN: 1792-1082
Journal Cover
December-2024 Volume 28 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2024 Volume 28 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data1.pdf
    • Supplementary_Data2.pdf
Article Open Access

MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein

  • Authors:
    • Yu-Feng Tian
    • Chi-Jung Huang
    • Chih-Yi Liu
    • Shung-Haur Yang
    • Chih-Sheng Hung
    • Kai-Yuan Lin
    • Ching-Long Lai
    • Chun-Chao Chang
  • View Affiliations / Copyright

    Affiliations: Department of Surgery, Chi Mei Medical Center, Tainan 710402, Taiwan, R.O.C., Department of Biochemistry, National Defense Medical Center, Taipei 114201, Taiwan, R.O.C., Department of Pathology, Sijhih Cathay General Hospital, New Taipei 221037, Taiwan, R.O.C., Department of Colorectal Surgery, National Yang‑Ming Chiao Tung University Hospital, Yilan 260006, Taiwan, R.O.C., School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei 242062, Taiwan, R.O.C., Department of Medical Research, Chi Mei Medical Center, Tainan 710402, Taiwan, R.O.C., Division of Basic Medical Sciences, Department of Nursing, Chang Gung University of Science and Technology, Taoyuan City 333324, Taiwan, R.O.C., Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei 110301, Taiwan, R.O.C.
    Copyright: © Tian et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 591
    |
    Published online on: October 4, 2024
       https://doi.org/10.3892/ol.2024.14724
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Colorectal cancer (CRC) is one of the most prevalent malignant diseases worldwide. Recurrence is associated with the poor survival of patients with CRC. Targeted therapy and precision medicine for recurrent CRC may improve the clinical outcome. Therefore, finding biomarkers that can detect CRC early, assess its prognosis and survival, and predict its treatment response is key to improving the clinical prognosis. The aim of this study was to assess CRC recurrence by analyzing molecular differences using postoperative specimens. Whole‑exome sequencing was first used to evaluate the molecular differences in CRC tissues from patients with recurrent disease, and the results were then verified with tissue array methods. The regulation of single nucleotide polymorphisms (SNPs) in long noncoding regions of interest was analyzed in the presence of target microRNAs (miRs) using luciferase assays. The results demonstrated that in patients with recurrent CRC, the G allele was mainly detected at the rs28382740 SNP in the 3'‑untranslated region of the X‑linked inhibitor of apoptosis (XIAP)‑encoding gene. From the tissue arrays, 60% (3/5) of patients with the G allele of the rs28382740 SNP were diagnosed with CRC recurrence, whilst only 10% (1/10) of patients without the G allele had recurrent CRC (P=0.077). Furthermore, XIAP levels were high in non‑CRC (50%; 2/4) and CRC (75%; 3/4) tissues of patients with recurrent disease and CRC (54.5%; 6/11) tissues of patients without recurrent disease. However, but only 9.1% (1/11) of non‑CRC tissues of nonrecurrent patients had significantly high XIAP expression levels (P=0.022). Using a luciferase assay, it was demonstrated that miR‑24s (miR‑24‑1‑5p and miR‑24‑2‑5p) targeting the rs28382740 SNP reduced XIAP levels in CRC cells with rs28382740 SNP genotype G. These results indicate that apoptosis‑related proteins, such as XIAP, may be therapeutic targets or biomarkers for tumor development. The data from the present study support an inhibitory effect of miR‑24s on XIAP expression. However, this inhibitory potency depends on the rs28382740 SNP genotype and may alleviate CRC progression by regulating the expression of XIAP.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

View References

1 

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 71:209–249. 2021. View Article : Google Scholar : PubMed/NCBI

2 

Balboa-Barreiro V, Pertega-Diaz S, Garcia-Rodriguez T, González-Martín C, Pardeiro-Pértega R, Yáñez-González-Dopeso L and Seoane-Pillado T: Colorectal cancer recurrence and its impact on survival after curative surgery: An analysis based on multistate models. Dig Liver Dis. 56:1229–1236. 2024. View Article : Google Scholar : PubMed/NCBI

3 

Zare-Bandamiri M, Fararouei M, Zohourinia S, Daneshi N and Dianatinasab M: Risk factors predicting colorectal cancer recurrence following initial treatment: A 5-year cohort study. Asian Pac J Cancer Prev. 18:2465–2470. 2017.PubMed/NCBI

4 

Ogunwobi OO, Mahmood F and Akingboye A: Biomarkers in colorectal cancer: Current research and future prospects. Int J Mol Sci. 21:53112020. View Article : Google Scholar : PubMed/NCBI

5 

Guraya SY: Pattern, stage, and time of recurrent colorectal cancer after curative surgery. Clin Colorectal Cancer. 18:e223–e228. 2019. View Article : Google Scholar : PubMed/NCBI

6 

Jia S, Zhang R, Li Z and Li J: Clinical and biological significance of circulating tumor cells, circulating tumor DNA, and exosomes as biomarkers in colorectal cancer. Oncotarget. 8:55632–55645. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Hao YX, Fu Q, Guo YY, Ye M, Zhao HX, Wang Q, Peng XM, Li QW, Wang RL and Xiao WH: Effectiveness of circulating tumor DNA for detection of KRAS gene mutations in colorectal cancer patients: A meta-analysis. Onco Targets Ther. 10:945–953. 2017. View Article : Google Scholar : PubMed/NCBI

8 

Tiedje V, Ting S, Herold T, Synoracki S, Latteyer S, Moeller LC, Zwanziger D, Stuschke M, Fuehrer D and Schmid KW: NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma. Oncotarget. 8:42613–42620. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Huang Q, Li S, Cheng P, Deng M, He X, Wang Z, Yang CH, Zhao XY and Huang J: High expression of anti-apoptotic protein Bcl-2 is a good prognostic factor in colorectal cancer: Result of a meta-analysis. World J Gastroenterol. 23:5018–5033. 2017. View Article : Google Scholar : PubMed/NCBI

10 

Su P, Yang Y, Wang G, Chen X and Ju Y: Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells. Int J Oncol. 53:1343–1353. 2018.PubMed/NCBI

11 

Sun D, Tao W, Zhang F, Shen W, Tan J, Li L, Meng Q, Chen Y, Yang Y and Cheng H: Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling. Signal Transduct Target Ther. 5:1742020. View Article : Google Scholar : PubMed/NCBI

12 

Zhou Y, Zhang X, Zhang J, Fang J, Ge Z and Li X: LRG1 promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation. PLoS One. 12:e01751222017. View Article : Google Scholar : PubMed/NCBI

13 

Miura K, Fujibuchi W, Ishida K, Naitoh T, Ogawa H, Ando T, Yazaki N, Watanabe K, Haneda S, Shibata C and Sasaki I: Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer. Surg Today. 41:175–182. 2011. View Article : Google Scholar : PubMed/NCBI

14 

Cetraro P, Plaza-Diaz J, MacKenzie A and Abadia-Molina F: A review of the current impact of inhibitors of apoptosis proteins and their repression in cancer. Cancers (Basel). 14:16712022. View Article : Google Scholar : PubMed/NCBI

15 

Hector S and Prehn JH: Apoptosis signaling proteins as prognostic biomarkers in colorectal cancer: A review. Biochim Biophys Acta. 1795:117–129. 2009.PubMed/NCBI

16 

Cheung CHA, Chang YC, Lin TY, Cheng SM and Leung E: Anti-apoptotic proteins in the autophagic world: An update on functions of XIAP, Survivin, and BRUCE. J Biomed Sci. 27:312020. View Article : Google Scholar : PubMed/NCBI

17 

Cao C, Mu Y, Hallahan DE and Lu B: XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer. Oncogene. 23:7047–7052. 2004. View Article : Google Scholar : PubMed/NCBI

18 

Devi Daimary U, Girisa S, Parama D, Verma E, Kumar A and Kunnumakkara AB: Embelin: A novel XIAP inhibitor for the prevention and treatment of chronic diseases. J Biochem Mol Toxicol. 36:e229502022. View Article : Google Scholar : PubMed/NCBI

19 

Devi GR: XIAP as target for therapeutic apoptosis in prostate cancer. Drug News Perspect. 17:127–134. 2004. View Article : Google Scholar : PubMed/NCBI

20 

Tong QS, Zheng LD, Wang L, Zeng FQ, Chen FM, Dong JH and Lu GC: Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells. Cancer Gene Ther. 12:509–514. 2005. View Article : Google Scholar : PubMed/NCBI

21 

Huang Q and Liu F: Ceramide analogue 5cc overcomes TRAIL-resistance by enhancing JNK activation and repressing XIAP expression in metastatic colon cancer cells. Chemotherapy. 68:210–218. 2023. View Article : Google Scholar : PubMed/NCBI

22 

Seo HG, Kim HB, Yoon JY, Kweon TH, Park YS, Kang J, Jung J, Son S, Yi EC, Lee TH, et al: Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. Cell Death Dis. 11:8152020. View Article : Google Scholar : PubMed/NCBI

23 

LaCasse EC: Pulling the plug on a cancer cell by eliminating XIAP with AEG35156. Cancer Lett. 332:215–224. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Oost TK, Sun C, Armstrong RC, Al-Assaad AS, Betz SF, Deckwerth TL, Ding H, Elmore SW, Meadows RP, Olejniczak ET, et al: Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J Med Chem. 47:4417–4426. 2004. View Article : Google Scholar : PubMed/NCBI

25 

Opo F, Rahman MM, Ahammad F, Ahmed I, Bhuiyan MA and Asiri AM: Structure based pharmacophore modeling, virtual screening, molecular docking and ADMET approaches for identification of natural anti-cancer agents targeting XIAP protein. Sci Rep. 11:40492021. View Article : Google Scholar : PubMed/NCBI

26 

Hosseinahli N, Aghapour M, Duijf PHG and Baradaran B: Treating cancer with microRNA replacement therapy: A literature review. J Cell Physiol. 233:5574–5588. 2018. View Article : Google Scholar : PubMed/NCBI

27 

Alves Dos Santos K, Clemente Dos Santos IC, Santos Silva C, Gomes Ribeiro H, de Farias Domingos I and Nogueira Silbiger V: Circulating exosomal mirnas as biomarkers for the diagnosis and prognosis of colorectal cancer. Int J Mol Sci. 22:3462020. View Article : Google Scholar : PubMed/NCBI

28 

Yuan D, Li K, Zhu K, Yan R and Dang C: Plasma miR-183 predicts recurrence and prognosis in patients with colorectal cancer. Cancer Biol Ther. 16:268–275. 2015. View Article : Google Scholar : PubMed/NCBI

29 

Moridikia A, Mirzaei H, Sahebkar A and Salimian J: MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer. J Cell Physiol. 233:901–913. 2018. View Article : Google Scholar : PubMed/NCBI

30 

Wang V and Wu W: MicroRNA-based therapeutics for cancer. BioDrugs. 23:15–23. 2009. View Article : Google Scholar : PubMed/NCBI

31 

Mollaei H, Safaralizadeh R and Rostami Z: MicroRNA replacement therapy in cancer. J Cell Physiol. 234:12369–12384. 2019. View Article : Google Scholar : PubMed/NCBI

32 

He X, Cheng G, Xiao F, Zhang L, Jin G, Zhao X, Liu Y, Liang J, Li Y, Liu Z, et al: miR-4477b gene as a novel pathogenic mutation occurring during the transformation of colorectal adenoma into colorectal cancer. J Gastrointest Oncol. 12:69–78. 2021. View Article : Google Scholar : PubMed/NCBI

33 

Li H and Durbin R: Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics. 26:589–595. 2010. View Article : Google Scholar : PubMed/NCBI

34 

McKenna A, Hanna M, Banks E, Sivachenko A, Cibulskis K, Kernytsky A, Garimella K, Altshuler D, Gabriel S, Daly M and DePristo MA: The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 20:1297–1303. 2010. View Article : Google Scholar : PubMed/NCBI

35 

Razali NN, Raja Ali RA, Muhammad Nawawi KN, Yahaya A and Mokhtar NM: Targeted sequencing of Cytokine-Induced PI3K-Related genes in ulcerative colitis, colorectal cancer and Colitis-Associated cancer. Int J Mol Sci. 23:114722022. View Article : Google Scholar : PubMed/NCBI

36 

Degalez F, Jehl F, Muret K, Bernard M, Lecerf F, Lagoutte L, Désert C, Pitel F, Klopp C and Lagarrigue S: Watch Out for a Second SNP: Focus on Multi-Nucleotide variants in coding regions and rescued Stop-Gained. Front Genet. 12:6592872021. View Article : Google Scholar : PubMed/NCBI

37 

McLaren W, Gil L, Hunt SE, Riat HS, Ritchie GR, Thormann A, Flicek P and Cunningham F: The ensembl variant effect predictor. Genome Biol. 17:1222016. View Article : Google Scholar : PubMed/NCBI

38 

Maran MIJ and Davis GD: Benefits of merging paired-end reads before pre-processing environmental metagenomics data. Mar Genomics. 61:1009142022. View Article : Google Scholar : PubMed/NCBI

39 

Xiang G, Wen X, Wang H, Chen K and Liu H: Expression of X-linked inhibitor of apoptosis protein in human colorectal cancer and its correlation with prognosis. J Surg Oncol. 100:708–712. 2009. View Article : Google Scholar : PubMed/NCBI

40 

Lin ZH, Lu MK, Lo HC, Chang CC, Tseng AJ, Chao CH and Lin TY: ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death. Int J Biol Macromol. 238:1241442023. View Article : Google Scholar : PubMed/NCBI

41 

Huang CJ, Pu CM, Su SY, Lo SL, Lee CH and Yen YH: Improvement of wound healing by capsaicin through suppression of the inflammatory response and amelioration of the repair process. Mol Med Rep. 28:1552023. View Article : Google Scholar : PubMed/NCBI

42 

Huang CJ, Yang SH, Lee CL, Cheng YC, Tai SY and Chien CC: Ribosomal protein S27-like in colorectal cancer: A candidate for predicting prognoses. PLoS One. 8:e670432013. View Article : Google Scholar : PubMed/NCBI

43 

Sherry ST, Ward MH, Kholodov M, Baker J, Phan L, Smigielski EM and Sirotkin K: dbSNP: The NCBI database of genetic variation. Nucleic Acids Res. 29:308–311. 2001. View Article : Google Scholar : PubMed/NCBI

44 

Hanifeh M and Ataei F: XIAP as a multifaceted molecule in cellular signaling. Apoptosis. 27:441–453. 2022. View Article : Google Scholar : PubMed/NCBI

45 

Jiang R, Su G, Chen X, Chen S, Li Q, Xie B and Zhao Y: Esculetin inhibits endometrial cancer proliferation and promotes apoptosis via hnRNPA1 to downregulate BCLXL and XIAP. Cancer Lett. 521:308–321. 2021. View Article : Google Scholar : PubMed/NCBI

46 

Liu F, Dai Z, Cheng Q, Xu L, Huang L, Liu Z, Li X, Wang N, Wang G, Wang L and Wang Z: LncRNA-targeting bio-scaffold mediates triple immune effects for postoperative colorectal cancer immunotherapy. Biomaterials. 284:1214852022. View Article : Google Scholar : PubMed/NCBI

47 

Hossain MS, Karuniawati H, Jairoun AA, Urbi Z, Ooi J, John A, Lim YC, Kibria KMK, Mohiuddin AKM, Ming LC, et al: Colorectal cancer: A review of carcinogenesis, global epidemiology, current challenges, risk factors, preventive and treatment strategies. Cancers (Basel). 14:17322022. View Article : Google Scholar : PubMed/NCBI

48 

Ganz A, Gandhi SR, Schafer J, Singh T, Puleo E, Mullett G and Wilson C: PERCEPT: indoor navigation for the blind and visually impaired. Annu Int Conf IEEE Eng Med Biol Soc. 2011:856–859. 2011.PubMed/NCBI

49 

Wolpin BM, Wei EK, Ng K, Meyerhardt JA, Chan JA, Selhub J, Giovannucci EL and Fuchs CS: Prediagnostic plasma folate and the risk of death in patients with colorectal cancer. J Clin Oncol. 26:3222–3228. 2008. View Article : Google Scholar : PubMed/NCBI

50 

Lygirou V, Fasoulakis K, Stroggilos R, Makridakis M, Latosinska A, Frantzi M, Katafigiotis I, Alamanis C, Stravodimos KG, Constantinides CA, et al: Proteomic analysis of prostate cancer FFPE samples reveals markers of disease progression and aggressiveness. Cancers (Basel). 14:37652022. View Article : Google Scholar : PubMed/NCBI

51 

Walter RF, Mairinger FD, Wohlschlaeger J, Worm K, Ting S, Vollbrecht C, Schmid KW and Hager T: FFPE tissue as a feasible source for gene expression analysis-a comparison of three reference genes and one tumor marker. Pathol Res Pract. 209:784–789. 2013. View Article : Google Scholar : PubMed/NCBI

52 

Lu C, Hong M, Chen B, Liu K, Lv Y, Zhou X and Su G: MicroRNA-215 regulates the apoptosis of HCT116 colon cancer cells by Inhibiting X-Linked inhibitor of apoptosis protein. Cancer Biother Radiopharm. 36:728–736. 2021.PubMed/NCBI

53 

Holcik M, Gibson H and Korneluk RG: XIAP: apoptotic brake and promising therapeutic target. Apoptosis. 6:253–261. 2001. View Article : Google Scholar : PubMed/NCBI

54 

Devi GR, Finetti P, Morse MA, Lee S, de Nonneville A, Van Laere S, Troy J, Geradts J, McCall S and Bertucci F: Expression of X-Linked inhibitor of apoptosis protein (XIAP) in breast cancer is associated with shorter survival and resistance to chemotherapy. Cancers (Basel). 13:28072021. View Article : Google Scholar : PubMed/NCBI

55 

Saha G, Sarkar S, Mohanta PS, Kumar K, Chakrabarti S, Basu M and Ghosh MK: USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma. Oncogene. 41:5061–5075. 2022. View Article : Google Scholar : PubMed/NCBI

56 

Zhang Y, Huang F, Luo Q, Wu X, Liu Z, Chen H and Huang Y: Inhibition of XIAP increases carboplatin sensitivity in ovarian cancer. Onco Targets Ther. 11:8751–8759. 2018. View Article : Google Scholar : PubMed/NCBI

57 

Delbue D, Mendonca BS, Robaina MC, Lemos LGT, Lucena PI, Viola JPB, Magalhães LM, Crocamo S, Oliveira CAB, Teixeira FR, et al: Expression of nuclear XIAP associates with cell growth and drug resistance and confers poor prognosis in breast cancer. Biochim Biophys Acta Mol Cell Res. 1867:1187612020. View Article : Google Scholar : PubMed/NCBI

58 

Gao X, Zhang L, Wei Y, Yang Y, Li J, Wu H and Yin Y: Prognostic value of XIAP level in patients with various cancers: A systematic review and Meta-Analysis. J Cancer. 10:1528–1537. 2019. View Article : Google Scholar : PubMed/NCBI

59 

Liu XG, Xu J, Li F, Li MJ and Hu T: Down-regulation of miR-377 contributes to cisplatin resistance by targeting XIAP in osteosarcoma. Eur Rev Med Pharmacol Sci. 22:1249–1257. 2018.PubMed/NCBI

60 

Jost PJ and Vucic D: Regulation of cell death and immunity by XIAP. Cold Spring Harb Perspect Biol. 12:a0364262020. View Article : Google Scholar : PubMed/NCBI

61 

Vucic D: XIAP at the crossroads of cell death and inflammation. Oncotarget. 9:27319–27320. 2018. View Article : Google Scholar : PubMed/NCBI

62 

Prabhu NB, Vinay CM, Satyamoorthy K and Rai PS: Pharmacogenomics deliberations of 2-deoxy-d-glucose in the treatment of COVID-19 disease: An in silico approach 3. Biotech. 12:2872022.

63 

Noguchi T, Toiyama Y, Kitajima T, Imaoka H, Hiro J, Saigusa S, Tanaka K, Inoue Y, Mohri Y, Toden S and Kusunoki M: miRNA-503 promotes tumor progression and is associated with early recurrence and poor prognosis in human colorectal cancer. Oncology. 90:221–231. 2016. View Article : Google Scholar : PubMed/NCBI

64 

Kou CH, Zhou T, Han XL, Zhuang HJ and Qian HX: Downregulation of mir-23b in plasma is associated with poor prognosis in patients with colorectal cancer. Oncol Lett. 12:4838–4844. 2016. View Article : Google Scholar : PubMed/NCBI

65 

Bonfrate L, Altomare DF, Di Lena M, Travaglio E, Rotelli MT, De Luca A and Portincasa P: MicroRNA in colorectal cancer: New perspectives for diagnosis, prognosis and treatment. J Gastrointestin Liver Dis. 22:311–320. 2013.PubMed/NCBI

66 

Yin Z, Zhou Y, Ma T, Chen S, Shi N, Zou Y, Hou B and Zhang C: Down-regulated lncRNA SBF2-AS1 in M2 macrophage-derived exosomes elevates miR-122-5p to restrict XIAP, thereby limiting pancreatic cancer development. J Cell Mol Med. 24:5028–5038. 2020. View Article : Google Scholar : PubMed/NCBI

67 

Yang L, Zhang L, Lu L and Wang Y: miR-214-3p regulates Multi-Drug resistance and apoptosis in retinoblastoma cells by targeting ABCB1 and XIAP. Onco Targets Ther. 13:803–811. 2020. View Article : Google Scholar : PubMed/NCBI

68 

Cheng Q, Zhang X, Xu X and Lu X: MiR-618 inhibits anaplastic thyroid cancer by repressing XIAP in one ATC cell line. Ann Endocrinol (Paris). 75:187–193. 2014. View Article : Google Scholar : PubMed/NCBI

69 

Chhichholiya Y, Suryan AK, Suman P, Munshi A and Singh S: SNPs in miRNAs and target sequences: Role in cancer and diabetes. Front Genet. 12:7935232021. View Article : Google Scholar : PubMed/NCBI

70 

Preskill C and Weidhaas JB: SNPs in microRNA binding sites as prognostic and predictive cancer biomarkers. Crit Rev Oncog. 18:327–340. 2013. View Article : Google Scholar : PubMed/NCBI

71 

Wang S, Liu N, Tang Q, Sheng H, Long S and Wu W: MicroRNA-24 in cancer: A double side medal with opposite properties. Front Oncol. 10:5537142020. View Article : Google Scholar : PubMed/NCBI

72 

Kohler C: Histochemical localization of caldesmon isoforms in colon adenocarcinoma and lymph node metastases. Virchows Arch. 459:81–89. 2011. View Article : Google Scholar : PubMed/NCBI

73 

Oh J, Oh JM and Cho SY: METTL3-mediated downregulation of splicing factor SRSF11 is associated with carcinogenesis and poor survival of cancer patients. Eur Rev Med Pharmacol Sci. 27:2561–2570. 2023.PubMed/NCBI

74 

Pan YJ, Huo FC, Kang MJ, Liu BW, Wu MD and Pei DS: Alternative splicing of HSPA12A pre-RNA by SRSF11 contributes to metastasis potential of colorectal cancer. Clin Transl Med. 12:e11132022. View Article : Google Scholar : PubMed/NCBI

75 

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ and Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 586:41–47. 2016. View Article : Google Scholar : PubMed/NCBI

76 

Menon A, Abd-Aziz N, Khalid K, Poh CL and Naidu R: miRNA: A promising therapeutic target in cancer. Int J Mol Sci. 23:115022022. View Article : Google Scholar : PubMed/NCBI

77 

Alnuaimi AR, Nair VA, Malhab LJB, Abu-Gharbieh E, Ranade AV, Pintus G, Hamad M, Busch H, Kirfel J, Hamoudi R and Abdel-Rahman WM: Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers. World J Gastrointest Oncol. 14:1637–1653. 2022. View Article : Google Scholar : PubMed/NCBI

78 

Qiao L, Dai Y, Gu Q, Chan KW, Zou B, Ma J, Wang J, Lan HY and Wong BC: Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer. Mol Cancer Ther. 7:2203–2211. 2008. View Article : Google Scholar : PubMed/NCBI

79 

Mukherjee S, Shelar B and Krishna S: Versatile role of miR-24/24-1*/24-2* expression in cancer and other human diseases. Am J Transl Res. 14:20–54. 2022.PubMed/NCBI

80 

Zhang H, Guo J, Mao L, Li Q, Guo M, Mu T, Zhang Q and Bi X: Up-regulation of miR-24-1-5p is involved in the chemoprevention of colorectal cancer by black raspberry anthocyanins. Br J Nutr. 122:518–526. 2019. View Article : Google Scholar : PubMed/NCBI

81 

Vucic D and Fairbrother WJ: The inhibitor of apoptosis proteins as therapeutic targets in cancer. Clin Cancer Res. 13:5995–6000. 2007. View Article : Google Scholar : PubMed/NCBI

82 

Nagaraju GP, Bramhachari PV, Raghu G and El-Rayes BF: Hypoxia inducible factor-1α: Its role in colorectal carcinogenesis and metastasis. Cancer Lett. 366:11–18. 2015. View Article : Google Scholar : PubMed/NCBI

83 

Belardinilli F, Capalbo C, Malapelle U, Pisapia P, Raimondo D, Milanetti E, Yasaman M, Liccardi C, Paci P, Sibilio P, et al: Clinical multigene panel sequencing identifies distinct mutational association patterns in metastatic colorectal cancer. Front Oncol. 10:5602020. View Article : Google Scholar : PubMed/NCBI

84 

Li HD and Liang C: Multigene panel predicting survival of patients with colon cancer. J Cancer. 10:6792–6800. 2019. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Tian Y, Huang C, Liu C, Yang S, Hung C, Lin K, Lai C and Chang C: MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein. Oncol Lett 28: 591, 2024.
APA
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K. ... Chang, C. (2024). MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein. Oncology Letters, 28, 591. https://doi.org/10.3892/ol.2024.14724
MLA
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K., Lai, C., Chang, C."MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein". Oncology Letters 28.6 (2024): 591.
Chicago
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K., Lai, C., Chang, C."MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein". Oncology Letters 28, no. 6 (2024): 591. https://doi.org/10.3892/ol.2024.14724
Copy and paste a formatted citation
x
Spandidos Publications style
Tian Y, Huang C, Liu C, Yang S, Hung C, Lin K, Lai C and Chang C: MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein. Oncol Lett 28: 591, 2024.
APA
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K. ... Chang, C. (2024). MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein. Oncology Letters, 28, 591. https://doi.org/10.3892/ol.2024.14724
MLA
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K., Lai, C., Chang, C."MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein". Oncology Letters 28.6 (2024): 591.
Chicago
Tian, Y., Huang, C., Liu, C., Yang, S., Hung, C., Lin, K., Lai, C., Chang, C."MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein". Oncology Letters 28, no. 6 (2024): 591. https://doi.org/10.3892/ol.2024.14724
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team