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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2024 Volume 28 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Efficacy and safety of anlotinib combined with S‑1 as a third‑ or later‑line treatment for advanced non‑small cell lung cancer in China: A systematic review and meta‑analysis

Haonan Xu, Yuwen Liang, Wenqiang Tang, Xiongxin Yang, Xiaobo Du
Article Number: 613
Published online on: 14 October 2024

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Case Report Open Access

Efficacy of the CV‑MED regimen in treating extramedullary involvement of multiple myeloma: A case report

Jinjie Gao, Fei Dong, Xu Zhang, Hongmei Jing
Article Number: 612
Published online on: 14 October 2024

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Case Report Open Access

Giant spindle cell rhabdomyosarcoma in an adult thorax: A case report

Yuqing Luo, Yao Li, Xue Meng, Shuai Luo, Xiang Huang, Jinjing Wang
Article Number: 611
Published online on: 14 October 2024

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Article Open Access

Dynamic susceptibility contrast‑enhanced perfusion magnetic resonance imaging parameters for predicting MGMT promoter methylation and prognostic value in newly diagnosed patients with glioblastoma 

Daiki Chida, Yoshiko Okita, Reina Utsugi, Hideki Kuroda, Ryuichi Hirayama, Noriyuki Kijima, Atsuko Arisawa, Naoki Kagawa, Yonehiro Kanemura, Shinichi Yoshimura, Noriyuki Tomiyama, Haruhiko Kishima
Article Number: 610
Published online on: 14 October 2024

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Article Open Access

Roles of deubiquitinases in urologic cancers (Review)

Liangpei Wu, Jiahui Wang, Lin Chai, Jun Chen, Xiaofeng Jin
Article Number: 609
Published online on: 14 October 2024

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Case Report Open Access

Recovery of temperature to normal may indicate the best time for surgery in patients with lung cancer complicated by a lung abscess: A case report

Yunbin Li, Yanping Tang, Xiaosong Li, Jian Li
Article Number: 608
Published online on: 14 October 2024

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Case Report Open Access

Plasma exchange as an effective treatment for cytokine release syndrome following T cell receptor‑engineered T cell immunotherapy: A case report

Xixi Zheng, Shuo Zhang, Haiting Wu, Jinghua Xia, Ke Zheng, Ying Wang, Yan Qin
Article Number: 607
Published online on: 14 October 2024

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Review Open Access

Emerging insights into ferroptosis in cholangiocarcinoma (Review)

Xiaoyue Zhao, Miao Zhang, Jing He, Xin Li, Xuewei Zhuang
Article Number: 606
Published online on: 14 October 2024

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Article Open Access

Chromatin accessibility is associated with therapeutic response in prostate cancer

Sanghoon Lee, Da Young Lee, Insuk So, Jung Nyeo Chun, Ju-Hong Jeon
Article Number: 605
Published online on: 14 October 2024

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Article Open Access

Plasmodium infection downregulates hypoxia‑inducible factor 1α expression to suppress the vascularization and tumorigenesis of liver cancer

Runling Wu, Xiao Chen, Huan Chen, Mei Li, Yun Liang
Article Number: 604
Published online on: 14 October 2024

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Article Open Access

Clinical significance of early kinetics of C‑reactive protein in patients with advanced urothelial carcinoma treated with pembrolizumab: Flare response and baseline levels predict oncological outcomes

Ikko Tomisaki, Mirii Harada, Shigeru Sakano, Michikazu Terado, Ryoichi Hamasuna, Shuji Harada, Hiroomi Matsumoto, Soichiro Akasaka, Yujiro Nagata, Akinori Minato, Ken-Ichi Harada, Naohiro Fujimoto
Article Number: 603
Published online on: 11 October 2024

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Review Open Access

Emergence of FLASH‑radiotherapy across the last 50 years (Review)

Menghua Li, Sen Zhou, Guofu Dong, Changzhen Wang
Article Number: 602
Published online on: 11 October 2024

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Article Open Access

Treatment of acute myeloid leukemia with active pulmonary tuberculosis with venetoclax‑based anti‑acute myeloid leukemia regimen combined with an intensive and then individualized anti‑tuberculosis regimen: A report of two cases

Lin Ji, Wei Yang, Liu Jie Gao, Bei Yuan Zhang, Ya Qing Xu, Xiao Feng Xu
Article Number: 601
Published online on: 11 October 2024

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Review Open Access

Biomarkers to predict the benefits of immune‑checkpoint blockade‑based therapy in patients with malignant peritoneal mesothelioma (Review)

Chunhong Wang, Yan Zhao, Wanru Liang
Article Number: 600
Published online on: 09 October 2024

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Case Report Open Access

Primary osteosarcoma of the kidney: A case report

Kun Zhang, Longguo Dai, Huijian Wan, Bingyu Zhu, Yang Wang, Enfa Ning, Feiyu Yin, Ji Li, Chongjina Zhang, Yu Bai
Article Number: 599
Published online on: 09 October 2024

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Case Report Open Access

Good response of stage IV melanoma to high‑dose radiation therapy combined with immunotherapy: A case report

Xuemei Deng, Kewei Xiang, Xingting He, Shuang Chen, Qingxi Guo, Hong Wu, Xiaolong Liu, Qinglian Wen, Hongru Yang
Article Number: 598
Published online on: 09 October 2024

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Article Open Access

Predictive model for acute radiation esophagitis in esophageal carcinoma based on prognostic nutritional index and systemic inflammatory index and its application

Lijun Wu, Wen Li, Xuanxuan Ma, Mengmeng Yuan, Yichun Wang, Shuwen Li
Article Number: 597
Published online on: 09 October 2024

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Review Open Access

Application of imaging technology for the diagnosis of malignancy in the pancreaticobiliary duodenal junction (Review)

Wanyi Yang, Pingsheng Hu, Chaohui Zuo
Article Number: 596
Published online on: 08 October 2024

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Article Open Access

Whole‑exome sequencing insights into synchronous bilateral breast cancer with discordant molecular subtypes

Shi-Han Hu, Bo Gao, Zheng-Jin Li, Ya-Chen Yuan
Article Number: 595
Published online on: 08 October 2024

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Retraction Open Access

[Retracted] Downregulated microRNA‑140‑5p expression regulates apoptosis, migration and invasion of lung cancer cells by targeting zinc finger protein 800

Enqing Zhuo, Changqing Cai, Wenzhe Liu, Kunsong Li, Wenzhen Zhao
Article Number: 594
Published online on: 07 October 2024

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Article Open Access

Expression of nuclear receptors and glucose metabolic pathway proteins in sebaceous carcinoma: Androgen receptor and monocarboxylate transporter 1 have a key role in disease progression

Youn Joo Choi, Min Kyu Yang, Namju Kim, Sang In Khwarg, Hokyung Choung, Ji Eun Kim
Article Number: 593
Published online on: 04 October 2024

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Article Open Access

Construction of a novel platelet‑related gene risk model to predict the prognosis and drug response in virus‑related hepatocellular carcinoma

Jing Zhang, Honglin Xiang, Ling Jiang, Mei Wang, Guodong Yang
Article Number: 592
Published online on: 04 October 2024

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Article Open Access

MicroRNA‑24 alleviates colorectal cancer progression via a rs28382740 single nucleotide polymorphism in the long noncoding region of X‑linked inhibitor of apoptosis protein

Yu-Feng Tian, Chi-Jung Huang, Chih-Yi Liu, Shung-Haur Yang, Chih-Sheng Hung, Kai-Yuan Lin, Ching-Long Lai, Chun-Chao Chang
Article Number: 591
Published online on: 04 October 2024

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Review Open Access

Role of ENPP1 in cancer pathogenesis: Mechanisms and clinical implications (Review)

Lujie Zhao, Yu Zhang, Yahui Tian, Xin Ding, Runling Lin, Lin Xiao, Fujun Peng, Kai Zhang, Zhongfa Yang
Article Number: 590
Published online on: 03 October 2024

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Review Open Access

Targeted gold nanoparticles for ovarian cancer (Review)

Wenjuan He, Fuyuan Yang, Keming Chen, Qingsong Zeng
Article Number: 589
Published online on: 03 October 2024

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Article Open Access

Transcriptomic analysis reveals Streptococcus agalactiae activation of oncogenic pathways in cervical adenocarcinoma

Hong Duc Thi Nguyen, Tan Minh Le, Da-Ryung Jung, Youngjae Jo, Yeseul Choi, Donghyeon Lee, Olive Em Lee, Junghwan Cho, Nora Jee-Young Park, Incheol Seo, Gun Oh Chong, Jae-Ho Shin, Hyung Soo Han
Article Number: 588
Published online on: 03 October 2024

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Article Open Access

Revolutionizing prognostic predictions in colorectal cancer: Macrophage‑driven transcriptional insights from single‑cell RNA sequencing and gene co‑expression network analysis

Yang Feng, Zhuo Cheng, Jingyuan Gao, Tao Huang, Jun Wang, Qian Tang, Ke Pu, Chang Liu
Article Number: 587
Published online on: 03 October 2024

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Article Open Access

α‑Fetoprotein‑positive hepatoid adenocarcinoma of the stomach and a new classification: A case report 

Zhen-Yu Ye, Chuan-Hai Xu, Wang Chen, Zhong-Ming Shao, Xue Zhao, Jin-Ling Tang, Xiang-Su Li, Xin Wang, Chao-Nan Wang, Qing-Qing Yang, Yang Huang, Xue-Yi Xiao, Xu-Dong Wu, Qi-Biao Wu
Article Number: 586
Published online on: 03 October 2024

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Review Open Access

Steroidal saponins: Natural compounds with the potential to reverse tumor drug resistance (Review)

Aiping Cui, Hai Liu, Xiaoxuan Liu, Minhong Zhang, Bang Xiao, Biao Wang, Jianqiong Yang
Article Number: 585
Published online on: 03 October 2024

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Case Report

Confirmed laryngeal sarcomatoid carcinoma after three vocal cord surgeries in a short period of time: A case report and literature review

Di Ji, Xinyu Liang, Li Zhao, Xianbai Zhu, Junjie Yang, Bo Liu, Anchun Deng, Xueqin Zhou
Article Number: 584
Published online on: 03 October 2024

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Case Report Open Access

Hyperbaric oxygen therapy enhances restoration of physical functional in patients with recurrent glioma: A case report

Tengteng Cai, Tao Jin, Yun Guan, Wei Zou, Xin Wang, Yulian Zhu
Article Number: 583
Published online on: 02 October 2024

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Article Open Access

Antitumour activity of oleanolic acid: A systematic review and meta‑analysis

Ying Zeng, Zhonglian Wang, Jing Zhang, Wei Jian, Qiaofen Fu
Article Number: 582
Published online on: 02 October 2024

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Article Open Access

Circulating methylated HOXA9 tumor DNA as a biomarker for mortality in recurrent breast cancer: An exploratory study

Stine Bakkensen Bruun, Rikke Fredslund Andersen, Jonna Skov Madsen, Torben Frøstrup Hansen, Tomasz Piotr Tabor, Troels Bechmann, Ina Mathilde Kjær
Article Number: 581
Published online on: 02 October 2024

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Article Open Access

β‑catenin expression in endometrioid type endometrial cancer: Expression patterns and impact on disease outcomes

Orkun Han, Aysun Alci, Hulya Tosun Yildirim, Mustafa Gokkaya, Necim Yalcin, Selim Kandemir, Mehmet Goksu, Isin Ureyen, Tayfun Toptas
Article Number: 580
Published online on: 02 October 2024

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Correction Open Access

[Corrigendum] Jak3 is involved in CCR7‑dependent migration and invasion in metastatic squamous cell carcinoma of the head and neck

Zhongti Zhang, Fayu Liu, Zhenning Li, Dan Wang, Ruiwu Li, Changfu Sun
Article Number: 579
Published online on: 02 October 2024

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Case Report Open Access

Furosemide‑induced eradication of myeloblasts via the inhibition of tumor necrosis factor‑α expression in a patient with acute biphenotypic leukemia: A case report

Yu-Wei Chang, Wan-Ru Chao, Yen-Ting Lai, Frank Sheng Fan
Article Number: 578
Published online on: 01 October 2024

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Article Open Access

Resveratrol inhibits Lin28A expression and induces its degradation via the proteasomal pathway in NCCIT cells

Sandra Cotino‑Nájera, Enrique García‑Villa, Samantha Cruz‑Rosales, Patricio Gariglio, José Díaz‑Chávez
Article Number: 577
Published online on: 30 September 2024

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Article Open Access

Pre‑operative mean platelet volume is associated with overall survival in patients with IDH‑wildtype glioblastoma undergoing maximal safe resection

Silvia Snider, Pierfrancesco De Domenico, Francesca Roncelli, Andrea Bisoglio, Matteo Braga, Anna Ghelfi, Lina Raffaella Barzaghi, Cinzia Mura, Pietro Mortini, Filippo Gagliardi
Article Number: 576
Published online on: 30 September 2024

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Retraction Open Access

[Retracted] p68 prompts the epithelial‑mesenchymal transition in cervical cancer cells by transcriptionally activating the TGF‑β1 signaling pathway

Ming-Yi Li, Jin-Quan Liu, Dong-Ping Chen, Zhou-Yu Li, Bin Qi, Wen-Jing Yin, Lu He
Article Number: 575
Published online on: 30 September 2024

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Review Open Access

Ferroptosis: Potential therapeutic targets and prognostic predictions for acute myeloid leukemia (Review)

Wenlu Zhang, Wen Wen, Ran Tan, Meirui Zhang, Tantan Zhong, Jianhong Wang, Haiping Chen, Xiaosheng Fang
Article Number: 574
Published online on: 30 September 2024

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Article Open Access

Modeling and prediction of set‑up errors in breast cancer image‑guided radiotherapy using the Gaussian mixture model

Fangfen Dong, Jing Chen, Feiyu Liu, Zhiyu Yang, Yimin Wu, Xiaobo Li
Article Number: 573
Published online on: 30 September 2024

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Article Open Access

USP5 promotes tumor progression by stabilizing SLUG in bladder cancer

Qiang-Kun Wan, Ting-Ting Li, Bei-Bei Liu, Bin He
Article Number: 572
Published online on: 27 September 2024

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Article Open Access

Comparison of postoperative prognoses for resectable colorectal cancer with vs. without oncologic emergency using propensity score‑matched analyses: A single-center retrospective observational study

Ken Imaizumi, Hiroyuki Kasajima, Kentaro Sato, Kentaro Ichimura, Aya Sato, Daisuke Yamana, Yosuke Tsuruga, Minoru Umehara, Michihiro Kurushima, Kazuaki Nakanishi
Article Number: 571
Published online on: 27 September 2024

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Article Open Access

Fotemustine in recurrent high‑grade glioma: MRI neuro‑radiological findings

Anna Paola Savoldi, Elena Anghileri, Marco Moscatelli, Antonio Silvani, Bianca Pollo, Cuccarini Valeria, Riccardo Pascuzzo, Domenico Aquino, Marina Grisoli, Fabio M. Doniselli
Article Number: 570
Published online on: 27 September 2024

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Article Open Access

Evaluation of immune checkpoint inhibitors for colorectal cancer: A network meta‑analysis

Chih-Chen Tzang, Yen-Wei Lee, Wei-Chen Lin, Long-Huei Lin, Yuan-Fu Kang, Ting-Yu Lin, Wei-Ting Wu, Ke-Vin Chang
Article Number: 569
Published online on: 27 September 2024

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Article Open Access

Clinical characteristics of gastrointestinal stromal tumors with hypoglycemia

Akihiko Chida, Kenta Kawasaki, Junko Kuramoto, Hideyuki Hayashi, Toru Kawahara, Satomi Makiuchi, Eiichiro So, Satoko Shimizu, Shotaro Kishimoto, Sara Horie, Yuki Saito, Keitaro Shimozaki, Kai Tsugaru, Kazuhiro Togasaki, Kenro Hirata, Hiroshi Nishihara, Yae Kanai, Takanori Kanai, Yasuo Hamamoto
Article Number: 568
Published online on: 26 September 2024

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Review

PI3K/AKT/mTOR and PD‑1/CTLA‑4/CD28 pathways as key targets of cancer immunotherapy (Review)

Shuangcui Wang, Changyu Liu, Chenxin Yang, Yutong Jin, Qian Cui, Dong Wang, Ting Ge, Guixin He, Wentao Li, Guan Zhang, Aqing Liu, Ying Xia, Yunhe Liu, Jianchun Yu
Article Number: 567
Published online on: 26 September 2024

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Case Report Open Access

Endobronchial lipoma with obstructive pneumonia: A case report

Yinjiao Wang, Peng Du
Article Number: 566
Published online on: 26 September 2024

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Article Open Access

Comparative effectiveness of two abbreviated rectal MRI protocols in assessing tumor response to neoadjuvant chemoradiotherapy in patients with rectal cancer

Filiz Taşçi, Yavuz Metin, Nurgül Orhan Metin, Sema Rakici, Melih Gaffar Gözükara, Erencan Taşçi
Article Number: 565
Published online on: 26 September 2024

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Article Open Access

Association between microsatellite instability status, clinicopathological features and mitochondrial DNA amplification in patients with colorectal cancer

Junmi Lu, Hong Tan, Tao Guo, Xi Chen, Zhongyi Tong
Article Number: 564
Published online on: 26 September 2024

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Review Open Access

Therapeutic efficacy of ferroptosis in the treatment of colorectal cancer (Review)

Zhao Guo, Haoyan Zhuang, Xuewen Shi
Article Number: 563
Published online on: 26 September 2024

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Article Open Access

Impact of infectious complications after gastrectomy on non‑gastric cancer‑related deaths

Chiyo Nakashima, Michihisa Iida, Mitsuo Nishiyama, Yusaku Watanabe, Yoshitaro Shindo, Yukio Tokumitsu, Shinobu Tomochika, Yuki Nakagami, Hidenori Takahashi, Hiroaki Nagano
Article Number: 562
Published online on: 26 September 2024

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Article

Preclinical evaluation of fenretinide against primary and metastatic intestinal type‑gastric cancer

Natalia Ortiz, Cecilia Díaz
Article Number: 561
Published online on: 25 September 2024

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Article Open Access

Therapeutic effects of paeonol on non‑small cell lung cancer cells via regulation of the MAPK pathway

Wen Gan, Chong Chen, Miaolong Huang, Youtao Li
Article Number: 560
Published online on: 24 September 2024

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Retraction Open Access

[Retracted] SRC‑like adaptor protein negatively regulates Wnt signaling in intrahepatic cholangiocarcinoma

Yong Wang, Xinxin He, Yangnian Wei, Ling Liu, Wen Wang, Nianfeng Li
Article Number: 559
Published online on: 23 September 2024

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Review Open Access

Anticancer role of flubendazole: Effects and molecular mechanisms (Review)

Xing Xing, Zongning Zhou, Hongwei Peng, Shaoping Cheng
Article Number: 558
Published online on: 20 September 2024

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Case Report Open Access

Metastatic prostate cancer presenting as generalized lymphadenopathy and progressing with inferior vena cava syndrome: A case report and literature review

Wen Wei, Chunyu Gong, Renjie Wei, Xu Luo, Yuhao Liu, Guo Chen, Ruitu Ran, Fudong Liu
Article Number: 557
Published online on: 19 September 2024

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Article Open Access

Association of human papillomavirus 16 and 18 with ovarian cancer risk: Insights from a meta‑analysis

Tan Minh Le, Hong Duc Thi Nguyen, Junghwan Cho, Nora Jee‑Young Park, Hyung Soo Han, Gun Oh Chong, Incheol Seo
Article Number: 556
Published online on: 19 September 2024

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Case Report Open Access

3D‑printed template‑guided iodine‑125 seed implantation to treat complete occlusion of the superior vena cava in pulmonary sarcomatoid carcinoma: A case report

Xuemin Di, Huimin Yu, Zhen Gao, Jinxin Zhao, Xiaoli Liu, Yansong Liang, Hongtao Zhang
Article Number: 555
Published online on: 19 September 2024

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Article Open Access

Synergistic effect of bazedoxifene and abemaciclib co‑treatment in triple‑negative breast cancer cells in vitro

Kailey Caroland, Changyou Shi, Jiayuh Lin
Article Number: 554
Published online on: 19 September 2024

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[Retracted] Long non‑coding RNA Igf2as controls hepatocellular carcinoma progression through the ERK/MAPK signaling pathway

Han Bao, Chun-Guang Guo, Peng-Cheng Qiu, Xin-Lei Zhang, Qi Dong, Yu-Kun Wang
Article Number: 553
Published online on: 18 September 2024

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January-2026 Volume 31 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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