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Review

Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)

  • Authors:
    • Xing Xu
    • Xue Zhang
    • Yang Zhao
    • Xiaoyang Zhang
    • Hongfang Tuo
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary Surgery, Hebei General Hospital, Shijiazhuang, Hebei 050057, P.R. China, Department of Pathology, Hebei General Hospital, Shijiazhuang, Hebei 050051, P.R. China
  • Article Number: 332
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    Published online on: May 7, 2025
       https://doi.org/10.3892/ol.2025.15078
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Abstract

Primary hepatocellular carcinoma (HCC) represents a malignancy of notable clinical concern, marked by elevated global incidence and mortality rates. Despite advancements in therapeutic modalities, HCC management remains challenged by the insidious onset of early‑stage disease and the limited efficacy of late‑stage surgical interventions. Transcatheter arterial chemoembolization (TACE) has evolved as a pivotal intervention for HCC, with recent innovations fostering synergistic combination strategies to augment therapeutic outcomes. Synthesizing contemporary clinical evidence and anticipating future advancements in TACE‑based multimodal approaches is imperative to refine therapeutic paradigms and optimize patient prognoses. The present review critically evaluates the current landscape of TACE‑centered multimodal therapies and explores emerging innovations poised to redefine therapeutic frontiers in HCC management.
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Copy and paste a formatted citation
Spandidos Publications style
Xu X, Zhang X, Zhao Y, Zhang X and Tuo H: Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review). Oncol Lett 30: 332, 2025.
APA
Xu, X., Zhang, X., Zhao, Y., Zhang, X., & Tuo, H. (2025). Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review). Oncology Letters, 30, 332. https://doi.org/10.3892/ol.2025.15078
MLA
Xu, X., Zhang, X., Zhao, Y., Zhang, X., Tuo, H."Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)". Oncology Letters 30.1 (2025): 332.
Chicago
Xu, X., Zhang, X., Zhao, Y., Zhang, X., Tuo, H."Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)". Oncology Letters 30, no. 1 (2025): 332. https://doi.org/10.3892/ol.2025.15078
Copy and paste a formatted citation
x
Spandidos Publications style
Xu X, Zhang X, Zhao Y, Zhang X and Tuo H: Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review). Oncol Lett 30: 332, 2025.
APA
Xu, X., Zhang, X., Zhao, Y., Zhang, X., & Tuo, H. (2025). Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review). Oncology Letters, 30, 332. https://doi.org/10.3892/ol.2025.15078
MLA
Xu, X., Zhang, X., Zhao, Y., Zhang, X., Tuo, H."Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)". Oncology Letters 30.1 (2025): 332.
Chicago
Xu, X., Zhang, X., Zhao, Y., Zhang, X., Tuo, H."Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)". Oncology Letters 30, no. 1 (2025): 332. https://doi.org/10.3892/ol.2025.15078
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