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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2025 Volume 30 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Chromophobe renal cell carcinoma with sarcomatoid change: A case report

Ae Ri Ahn, Sang Jae Noh, Young Bum Jeong, Kyoung Min Kim
Article Number: 371
Published online on: 28 May 2025

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Review Open Access

Diagnostic methods for pancreatic cancer and their clinical applications (Review)

Juan Zhao, Jiahuan Wang, Yuanlong Gu, Xiaoyi Huang, Linyou Wang
Article Number: 370
Published online on: 27 May 2025

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Case Report Open Access

Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report

Yun He, Huanfang Fan, Zhihua Du, Dehui Li, Yiting Gu, Zihui Liu
Article Number: 369
Published online on: 27 May 2025

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Review Open Access

Gut microbiome versus thyroid cancer: Association and clinical implications (Review)

Mali Wang, Yuchun Zhu
Article Number: 368
Published online on: 27 May 2025

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Case Report Open Access

Six‑year survival after oral temozolomide maintenance therapy in limited‑stage small cell lung cancer: A case report

Daixi Wu, Yangbo Xu, Chao Wang, Tao Xu, Yuqi Gu, Xiaojia Zhang, Aolin Wang, Huijuan Cui
Article Number: 367
Published online on: 27 May 2025

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Article Open Access

Factors influencing pathological complete response to neoadjuvant chemotherapy in resectable breast cancer: A retrospective study

Jian Kang, Huifen Xiong, Xiaoliu Jiang, Zhaohui Huang, Yonghong Guo, Yali Cao, Jingxian Ding
Article Number: 366
Published online on: 27 May 2025

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Retraction Open Access

[Retracted] Upregulation of miR‑34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC‑7901 cells through inhibition of the PI3K/Akt signaling pathway

Guojun Wang, Guanghui Liu, Yanwei Ye, Yang Fu, Xiefu Zhang
Article Number: 365
Published online on: 27 May 2025

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Article Open Access

Changes in thyroid hormone levels indicate immunotherapy efficacy in gastric cancer

Min Xiao, Lan Liu Qian, Qiu Zhao, Jian Ma, Qianxiao Li, Qian Liu, Zhiyan Bi
Article Number: 364
Published online on: 26 May 2025

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Article Open Access

Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 363
Published online on: 23 May 2025

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Article Open Access

Identification and validation of prognostic models and tumor microenvironment infiltration characteristics for tRNA modification regulators in clear cell renal cell carcinoma

Xu Zhu, Cheng Shen, Wei Zhang, Yuanfei Ji, Siyang Xu, Bing Zheng, Zhan Chen
Article Number: 362
Published online on: 22 May 2025

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Article Open Access

OSW‑1 inhibits tumor cell proliferation and migration via uncoupling protein 2 in hepatocellular carcinoma

Kaiwen Shen, Xinglin Jin
Article Number: 361
Published online on: 22 May 2025

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Article Open Access

Application of serum anti‑ENO1 and anti‑SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer

Satoshi Yajima, Masaaki Ito, Takashi Suzuki, Yoko Oshima, Makoto Sumazaki, Fumiaki Shiratori, Hirotaka Takizawa, Shu-Yang Li, Bo-Shi Zhang, Yoichi Yoshida, Tomoo Matsutani, Takaki Hiwasa, Hideaki Shimada
Article Number: 360
Published online on: 22 May 2025

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Article Open Access

Prognosis and influencing factors of patients with different lymph node statuses after pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer

Jianxi Zhou, Yunchuan Sun, Li Xiao, Hongling Lu, Xiaoming Yin, Yaru Kong, Yiyan Zhang, Wei Guo, Yingnan Zhou
Article Number: 359
Published online on: 22 May 2025

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Case Report

Malignant mesothelioma with a novel BAP1 germline frameshift mutation treated with dual immune checkpoint inhibitors: A case report

Na Zhou, Mingying Wu, Chenyu Wang, Mingming Yuan, Yuejuan Cheng, Huanwen Wu, Xin Gao, Shuangni Yu, Lin Zhao
Article Number: 358
Published online on: 21 May 2025

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Article Open Access

In vitro and in silico investigation of the critical role of GABAB receptor activation in human breast cancer and its natural agonists

Mustafa Hussein Ali, Ziyad Tariq Muhseen, Zahraa Yousif Al-Hajjaj, Hussein Hazim Al-Ghanimi, Abdulrahman Alshammari, Norah Abdullah Albekairi
Article Number: 357
Published online on: 21 May 2025

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Article Open Access

Integration of dual‑source dual‑energy CT quantitative parameters and ultrasound image features: A diagnostic method for extraglandular invasion of papillary thyroid carcinoma

Muhammad Asad Iqbal, Nida Fatima Moazzam, Hui Zhou, Jie Hou, Hui Sun, Donggang Pan, Xian Wang
Article Number: 356
Published online on: 21 May 2025

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Correction Open Access

[Corrigendum] Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation

Lina Qiao, Jianbao Zheng, Xianzhen Jin, Guangbing Wei, Guanghui Wang, Xuejun Sun, Xuqi Li
Article Number: 355
Published online on: 21 May 2025

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Review Open Access

Evolving role of deubiquitinating enzymes in oral cancer (Review)

Zidi Wang, Siyuan Cheng, Jianhui Wei, Jiandong Hu, Fenge Li, Wenhua Yang
Article Number: 354
Published online on: 19 May 2025

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Article Open Access

Role of the SPI1/CDKN2A/p53 signaling pathway in cuproptosis of lung adenocarcinoma cells

Jiayue An, Wei Song, Qin Wang, Boyu Tan, Xuan Fei, Ruoxi Wang, Siyan Li, Xiyu Lu, Youjie Li, Ning Xie
Article Number: 353
Published online on: 19 May 2025

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Case Report Open Access

Rechallenge of anti‑PD‑1 antibody combined with chemotherapy shows promising efficacy in the treatment of advanced metastatic hepatocellular carcinoma: A case report

Xiang Tan, Le Kang, Hao Chen, Xingyan Liu, Chi Du
Article Number: 352
Published online on: 19 May 2025

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Retraction Open Access

[Retracted] Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao
Article Number: 351
Published online on: 19 May 2025

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Article Open Access

Comprehensive analysis of a palmitoylation‑related prognostic signature in colorectal cancer: Implications for immune therapy and personalized treatment

Xiaokang Wang, Jian Li, Zi Wang, Qingyun Wu
Article Number: 350
Published online on: 16 May 2025

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Case Report Open Access

Pancreatic metastasis from cervical cancer: A case report and literature review

Hailing Liao, Xiaoyan Chang, Xiaorong Hou, Fuquan Zhang
Article Number: 349
Published online on: 16 May 2025

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Article Open Access

Efficacy and safety of BCG and immune checkpoint inhibitors in non‑muscle invasive bladder cancer: A meta‑analysis with exploratory chemotherapy comparisons

Mohamed Mohamoud Adan, Xudong Mao, Lifeng Ding, Khalid Mohamoud Abdullahi, Gonghui Li
Article Number: 348
Published online on: 16 May 2025

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Case Report Open Access

Arterial perfusion chemoembolization combined with iodine‑125 seeds for stage IIB osteosarcoma: A case report

Linhao Ran, Fan Li, Li Jiang, Li Yang, Ying Liu
Article Number: 347
Published online on: 15 May 2025

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Article Open Access

Long‑term follow‑up outcomes of intraoperative radiotherapy for breast‑conserving treatment in early breast cancer: A retrospective cohort study

Xiaofan Xu, Lu Wang, Yuanyuan Cao, Jingyi Wang, Jie Yao, Liqun Huo, Yuqing Song, Wei Ding, Jun Gu, Qiurong Li
Article Number: 346
Published online on: 15 May 2025

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Article Open Access

Utility of the CPS + EG score with real‑life data in patients with breast cancer undergoing neoadjuvant chemotherapy

Ezgi Yildiz Yurekli, Seval Akay, Olcun Umit Unal
Article Number: 345
Published online on: 15 May 2025

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Case Report Open Access

Fan beam computed tomography‑guided online adaptive external radiotherapy for cervical cancer achieves pathological complete response: A case report

Haibo Peng, Ningyue Xu, Dong Gao, Huigang Tan, Tao Ren
Article Number: 344
Published online on: 14 May 2025

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Case Report Open Access

Spinal cord metastasis in a long‑term survivor of primary malignant glioblastoma: A case report 

Pengwei Hou, Meiyan Liu, Ziqi Li, Mingfa Cai, Chenzhu Cai
Article Number: 343
Published online on: 14 May 2025

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Review Open Access

Combination of radiotherapy and ICIs in advanced hepatocellular carcinoma: A systematic review of current evidence and future prospects (Review)

Cheng Ma, Xinlin Yu, Xialin Zhang, Lihong Su, Ou Jiang, Ran Cui
Article Number: 342
Published online on: 14 May 2025

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Article Open Access

Application and clinical translational value of a predictive model based on N7‑methylguanosine‑related long non‑coding RNAs in cervical squamous cell carcinoma

Jun Zhang, Yingna Bao, Zhilong Yu, Yu Lin
Article Number: 341
Published online on: 14 May 2025

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Case Report Open Access

Cerebral metastasis from anal squamous cell carcinoma: A case report and literature review

Elena Andreea Popa, Vanesa Marisa Tomatis, Esther Quick, Paul Stephen Mitchell, Chrisovalantis Tsimiklis, Annika Reann Mascarenhas
Article Number: 340
Published online on: 13 May 2025

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Article Open Access

AMIGO2 expression at the invasive front of bladder cancer predicts recurrence‑free and overall survival after radical cystectomy

Atsushi Yamamoto, Runa Izutsu, Heekyung Seong, Ryutaro Shimizu, Ryoma Nishikawa, Yusuke Kimura, Noriya Yamaguchi, Shuichi Morizane, Katsuya Hikita, Masashi Honda, Atsushi Takenaka, Futoshi Okada
Article Number: 339
Published online on: 13 May 2025

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Case Report Open Access

Primary pulmonary malignant melanoma with H3K27Me3 loss: A case report

Houqiang Li, Lanqing Zheng, Xunbin Yu, Linfeng Chen, Shanshan Lv, Xin Chen
Article Number: 338
Published online on: 13 May 2025

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Case Report Open Access

Successful robot‑assisted minimally invasive surgery for scirrhous gastric conduit cancer after esophagectomy: A case report

Koichi Okamoto, Yuta Sannomiya, Koki Furuse, Kaori Maruyama, Hisashi Nishiki, Akifumi Hashimoto, Daisuke Kaida, Takashi Miyata, Toshikatsu Tsuji, Hideto Fujita, Noriyuki Inaki, Shinichi Kinami, Itasu Ninomiya, Hiroyuki Takamura
Article Number: 337
Published online on: 12 May 2025

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Retraction Open Access

[Retracted] Metformin mitigates PLCε gene expression and modulates the Notch1/Hes and androgen receptor signaling pathways in castration‑resistant prostate cancer xenograft models

Qi Li, Ke Xu, Jianguo Tian, Zhicheng Lu, Jianming Pu
Article Number: 336
Published online on: 12 May 2025

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Article Open Access

Retroperitoneal growth of high‑grade serous ovarian carcinoma: A case report

Pengnan Hu, Weizhou Pan, Jun Yu, Hua Mi
Article Number: 335
Published online on: 09 May 2025

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Article Open Access

Establishment and evaluation of an automatic multi‑sequence MRI segmentation model of primary central nervous system lymphoma based on the nnU‑Net deep learning network method

Tao Wang, Xingru Tang, Jun Du, Yongqian Jia, Weiwei Mou, Guang Lu
Article Number: 334
Published online on: 09 May 2025

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Case Report

Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report 

Binh Van Pham, Duy Duc Nguyen, Manh Dai Tran, Thanh Duy Nguyen, An Duc Thai, Binh Tien Nguyen, Ky Van Le, Hoa Thi Thanh Nguyen
Article Number: 333
Published online on: 08 May 2025

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Review

Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)

Xing Xu, Xue Zhang, Yang Zhao, Xiaoyang Zhang, Hongfang Tuo
Article Number: 332
Published online on: 07 May 2025

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Case Report Open Access

Breast cancer metastasis to the nasopharynx: A case report

Yandong Bian, Chen Song, Yuhui Nie, Xin Shen, Fu Hui, Guohua Yu
Article Number: 331
Published online on: 07 May 2025

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Article Open Access

Distinguishing acute leukemia subtypes: The role of hsa_circ_0012152 and hsa_circ_0020093 in peripheral blood

Qiming Ying, Dingfeng Lv, Ying Chen, Qitian Mu
Article Number: 330
Published online on: 07 May 2025

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Retraction Open Access

[Retracted] lncRNA‑CD160 decreases the immunity of CD8+ T cells through epigenetic mechanisms in hepatitis B virus infection

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 329
Published online on: 06 May 2025

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Article Open Access

Efficacy and safety of furmonertinib in patients with EGFR‑mutant advanced lung adenocarcinoma after failure of multiple lines of therapy: A single‑center retrospective study

Yumin Zheng, Xingyu Lu, Huijing Dong, Jia Li, Yulei Shen, Zhening Liu, Huijuan Cui
Article Number: 328
Published online on: 02 May 2025

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Article Open Access

Prophylactic cerebral irradiation sensitizes relapsed sensitive small cell lung cancer to temozolomide: A retrospective cohort study

Dan He, Shuxia Wei, Fenghao Geng, Lintao Li, Fengyu Li, Yanli Ge, Ruichang Lv, Weiwei Li, Zhijun Hao, Fengdi Jiang, Chao Meng, Shun Lu, Shuyu Zhang
Article Number: 327
Published online on: 02 May 2025

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Case Report Open Access

Sintilimab‑induced acute erosive hemorrhagic gastritis as an adverse reaction of third‑line therapy in a nasopharyngeal carcinoma patient: A case report

Wenqiang Tang, Yun Lv, Xiyue Yang, Kunyuan Gan, Gang Feng, Jie Li, Lu Ni, Yuxi Bai, Xiaobo Du, Feng Gao
Article Number: 326
Published online on: 02 May 2025

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Review Open Access

Application of multivalent aptamers in tumor diagnosis, analysis and therapy (Review)

Hongyue Zeng, Wenjing Zeng, Yaoyao Liang
Article Number: 325
Published online on: 02 May 2025

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Article

AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells

Gulsum Altiparmak-Ulbegi, Gozde Hasbal-Celikok, Pinar Aksoy-Sagirli
Article Number: 324
Published online on: 02 May 2025

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Article Open Access

Prognostic value of the pretreatment Glasgow prognostic score or modified Glasgow prognostic score in patients with advanced cancer receiving immune checkpoint inhibitors: A systematic review and meta‑analysis

Lianghui Zhang, Lili Lin, Jie Ni, Tao Ling, Lingli Huang
Article Number: 323
Published online on: 02 May 2025

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Article Open Access

Establishment and validation of a clinical prediction model for colorectal adenoma risk factors

Dong-Lin Li, Ling-Ling Ma, Zhong-An Guan, Yu-Xin Zhao, Chuan Jiang
Article Number: 322
Published online on: 02 May 2025

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Case Report Open Access

Pulmonary pleomorphic carcinoma associated with cystic airspace and recurrent spontaneous pneumothorax: A case report

Qiangsheng Li, Jing Zhang, Youjie Gong, Xudong Wan, Song Zhang, Zhongwang Li, Jun Liu
Article Number: 321
Published online on: 02 May 2025

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Case Report Open Access

Composite B‑cell lymphoma and extranodal natural killer/T‑cell lymphoma presenting with distinct clone evolution and tumor microenvironment: A report of two cases

Qiuyue Wen, Qiuhui Li, Wei Yang, Xiaona Chang, Fang Zhu, Huaxiong Pan, Liling Zhang
Article Number: 320
Published online on: 02 May 2025

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Journal Cover
January-2026 Volume 31 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Predictive analysis of BRAF V600E mutation and central lymph node metastasis in papillary thyroid carcinoma

Junhui Peng, Zhihui Wu, Yujun Huang, Runhua Pan, Zhongdai Fu, Jianzhang Wang
Article Number: 44
Published online on: 24 November 2025

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Case Report Open Access

Adverse events induced by the subcutaneous HER2-targeted antibody‑drug conjugate JSKN033 in a male patient with breast cancer: A case report

Rui Yang, Jian Zhang, Yang Wang
Article Number: 43
Published online on: 24 November 2025

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Article Open Access

Prediction of solitary ≤3‑cm small adrenal metastasis based on 18F‑FDG PET/CT using a support vector machine model in lung cancer

Lin Zhao, Haifeng Cai, Jingwu Li, Wenzhe Zhao, Yongliang Liu, Lixiu Cao
Article Number: 42
Published online on: 24 November 2025

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Article Open Access

Transferrin receptor serves a role in promoting PANoptosis in thyroid cancer

Shungao Ma, Zhiqiang Ma, Jingwei Shen, Hong Liu, Hua Yang, Yuqin Hu, Simeng Ying
Article Number: 41
Published online on: 24 November 2025

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Review Open Access

Oxidative stress as a nexus: Integrating mitophagy and ferroptosis in endometrial carcinogenesis (Review)

Qixia Yu, Liangxin Ren, Feng Ren, Fengling Li
Article Number: 40
Published online on: 20 November 2025

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Review Open Access

Astragalin: A promising herbal compound with broad anticancer potential (Review)

Yu-Qian Fu, Chan Li, Dan-Ni Ding, Fang-Yuan Liu, Yu-Fei Zhu, Feng-Juan Han
Article Number: 39
Published online on: 20 November 2025

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Article Open Access

Analysis of prognostic factors influencing brain metastasis in EGFR‑mutant lung adenocarcinoma and comparison of prognostic assessment models

Junjun Miao, Jianwei Hu, Yongxia Zhang, Lei Gao, Xiangkun Yuan
Article Number: 38
Published online on: 18 November 2025

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Case Report

Fumarate hydratase-deficient renal cell carcinoma arising in acquired cystic kidney disease in a hemodialysis patient: Diagnostic clues from percutaneous renal mass core needle biopsy: A case report

Yuki Oba, Hisashi Kamido, Kei Kono, Katsuyuki Miki, Shinji Ito, Akinari Sekine, Shigekazu Kurihara, Masayuki Yamanouchi, Tatsuya Suwabe, Yutaka Takazawa, Kenichi Ohashi, Yoji Nagashima, Yuki Nakamura, Yoshifumi Ubara, Naoki Sawa
Article Number: 37
Published online on: 18 November 2025

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Article Open Access

TIMP1 expression in colorectal cancer: Linking prognosis, tumor immunity and molecular pathways

Jiming Gu, Dongming Zhu, Fan Chen, Tongguo Shi, Suhua Xia
Article Number: 36
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Exosomes from LNCaP cells promote osteoblast activity through miR‑375 transfer

Su-Liang Li, Na An, Bing Liu, Sheng-Yu Wang, Jian-Jun Wang, Yun Ye
Article Number: 35
Published online on: 17 November 2025

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Article

TAS‑102 plus bevacizumab as salvage treatment in colorectal cancer: A retrospective study

Keita Matsumoto, Ryoma Yokoi, Chika Mizutani, Ryuichi Asai, Jesse Yu Tajima, Masahide Endo, Yuji Hatanaka, Takeshi Horaguchi, Masahiro Fukada, Itaru Yasufuku, Yuta Sato, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi
Article Number: 34
Published online on: 14 November 2025

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Review Open Access

Research progress on neutrophil extracellular traps and hepatitis‑to‑hepatocellular carcinoma transformation (Review)

Yiwei Wang, Chengyan Zhang, Haonan Wang, Yali Zhou, Yuanbo Yu, Hui Liu, Chuansha Gu
Article Number: 33
Published online on: 14 November 2025

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Case Report Open Access

Remarkable response to Osimertinib plus Gumarontinib for EGFR mutation and concomitant MET exon 14 skipping in a patient with lung adenocarcinoma: A case report

Xuquan Jing, Li Li, Shuangqing Lu, Xiaoyang Zhai, Hui Zhu
Article Number: 32
Published online on: 12 November 2025

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Article Open Access

Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene

Yufan Zhou, Wei Liu, Zhixue Fang, Ke Zhou, Xing Huang, Shanzheng Lu, Weilin Zhang, Qiaocheng Wen, Xu Chen, Zhigang Xiao
Article Number: 31
Published online on: 12 November 2025

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Case Report Open Access

Dual immune checkpoint inhibitor cardonilumab induces immune myocarditis in a patient with cancer‑related myocardial metastasis: A case report

Tianxing Liu, Qiang Li, Renya Zeng, Baidong Zhang, Zhichao Kang, Pengfei Zhang, Zhe Yang
Article Number: 30
Published online on: 12 November 2025

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Article Open Access

Retrospective analysis of clinical characteristics, treatment outcomes and prognosis of patients with natural killer/T‑cell lymphoma

Pengye Li, Geraldine Esther Awakossa, Lu Zhou, Qiuhui Li, Xinxiu Liu, Fang Zhu, Tao Liu, Liling Zhang
Article Number: 29
Published online on: 11 November 2025

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From mechanism to targeted therapy: Advances in histone lactylation‑driven cancer progression (Review)

Zhe Jia, Shan Lu, Zhenchuan Wang, Pengfei Ge
Article Number: 28
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non‑coding RNA promotes esophageal squamous cell carcinoma progression

Xiaojun Wang, Liangfen Zhou, Huiyun Zhang, Hui Ou, Wenxing Long, Xiaobao Liu
Article Number: 27
Published online on: 10 November 2025

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Review Open Access

Biology of PEST‑containing nuclear proteins as potential targets in ovarian cancer (Review)

Hao Liu, Zhi-Liang Jiang, Yi Liu, Yong-Hao Zhu, Muhammad Usman Akbar, Saadullah Khattak, Zhendong Lu, Muhammad Babar Khawar, Yue Zhang, Umair Ali Khan Saddozai, Xin-Ying Ji
Article Number: 26
Published online on: 07 November 2025

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Article

Survival outcomes and prognostic factors in temporal bone malignancies: A retrospective cohort of 20 patients

Liming Gao, Wenyang Zhang, Ting Ye, Rui Guo, Yin Xia
Article Number: 25
Published online on: 06 November 2025

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Article Open Access

Real‑world performance of the machine learning‑based prediction of chemotherapy‑associated adverse effects in lung cancer

Sha Huang, Zhengwei Huang, Zhoujian Sun, Tianao Xie, Xingyu Zhu, Sheng Lu, Zhengxing Huang, Jian Hu, Zhengfu He
Article Number: 24
Published online on: 06 November 2025

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Article Open Access

Long non‑coding RNA RP11‑196G11.6 inhibits neuroblastoma progression by regulating the miR‑376a‑3p/RYBP signaling axis

Jie Zhang, Kai Huang, Jianwu Zhou, Wenge Liao, Fei Li, Zhenzhen Zhao, Shan Wang
Article Number: 23
Published online on: 06 November 2025

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Review

Cervical cancer immune microenvironment: Mechanisms of HPV‑mediated immune evasion and advances in immunotherapy (Review)

Xiaojing Zhou, Ren An, Xiangjuan Li
Article Number: 22
Published online on: 05 November 2025

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Mesenchymal stem cell‑derived exosomes: Regulators of progression and suppression in pancreatic cancer (Review)

Haoyan Zhuang, Xuewen Shi
Article Number: 21
Published online on: 04 November 2025

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Review Open Access

Advancements in research regarding the influence of the tumor microenvironment on the proliferation and metastasis of osteosarcoma (Review)

Tao Shi, Jianping Kang, Qiyang Wang, Jiamei Song, Xiaofeng He
Article Number: 20
Published online on: 04 November 2025

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Article Open Access

Enhanced expression of CXCL1 in renal cell carcinoma facilitates tumor cell malignancy via PI3K/AKT‑dependent mechanisms

Shiliang Gui, Hongrui Zhang, Huiting Xiao, Chen Liu, Yuhang Wang, Baotian Wang, Hongbin Qiu
Article Number: 19
Published online on: 03 November 2025

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Case Report Open Access

Photodynamic therapy with local‑targeted perfusion for recurrent tracheal adenoid cystic carcinoma achieving 12‑year survival: A case report

Luoqi Yang, Lu Wang, Hongwu Wang, Heng Zou
Article Number: 18
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG‑3‑regulated wnt/β‑catenin signaling pathway

Xin Li, Lei Xue, Qin Peng
Article Number: 17
Published online on: 03 November 2025

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Article Open Access

Non‑targeted metabolomics reveals diagnostic biomarker in the plasma of patients with lung cancer

Yan Liu, Yangmin Li, Haijun Hou, Yanyan Dong, Haitong Tian, Yanan Zhao, Ke Li, Jiayuan Zhou, Fujie Song, Yan Li
Article Number: 16
Published online on: 31 October 2025

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Article Open Access

Primary pulmonary angiosarcoma: A case study with genetic insights and potential therapeutic targets

Yanling Zhu, Chunfang Guo
Article Number: 15
Published online on: 31 October 2025

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Review Open Access

Progress in the treatment of esophageal neuroendocrine carcinoma (Review)

Jie Shi, Bin He, Heng Di Zhang, Chao Yang Jiang, Ling Zhang
Article Number: 14
Published online on: 31 October 2025

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Article Open Access

Sensitive cell‑free DNA assay for accurate detection of RAS and BRAF mutations in liquid biopsies of patients with metastatic colorectal cancer: Final results of the multicentric ColoBEAM study

Alexandre Harlé, Céline Gavoille, Olivier Bouché, Meher Ben Abdelghani, Jérome Plaza, Dominique Spaeth, Axelle Boudrant, François Ghiringhelli, Anne-Laure Villing, Christophe Borg, Marie Rouyer, Marie Husson, Pauline Gilson, Julia Salleron, Aurélien Lambert, Jean-Louis Merlin
Article Number: 13
Published online on: 30 October 2025

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Article

Single‑center retrospective study of factors associated with early discontinuation of tumor‑treating fields therapy in glioblastoma

Kohei Suzuki, Koichiro Sato, Shohei Nagasaka, Ryo Miyaoka, Takeshi Saito, Yoshiteru Nakano, Nayuta Higa, Toshiaki Akahane, Akihide Tanimoto, Ryosuke Hanaya, Junkoh Yamamoto
Article Number: 12
Published online on: 29 October 2025

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Review Open Access

Clinical value of emerging peripheral blood protein biomarkers in prostate cancer (Review)

Mengli Chen, Feng Wang, Weixi Wang, Kangle Feng, Kaihua Xiang, Xubo Gong, Zhihua Tao, Weiwei Liu
Article Number: 11
Published online on: 29 October 2025

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Article Open Access

Intratumoral and peritumoral radiomics of MRI predict pathological differentiation in patients with rectal cancer

Huanhui Liu, Hanjing Zhang, Qian Zou, Jianquan Yang
Article Number: 10
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

Li Deng, Taiyuan Li, Yuanyuan Liao, Shuang Liu, Zhen Xie, Zhixiang Huang, Hua Dai, Jianfeng Li, Xiong Lei
Article Number: 9
Published online on: 27 October 2025

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Case Report Open Access

Combined BRAF/MEK inhibition for BRAF‑mutant melanoma brain metastases in pregnancy: A case report

Jaroslav Melus, Michaela Jezberova, Silvia Mikulajova, Katarina Komaromy Gerincova, Martin Karlik, Igor Straka, Marek Krivosik, Peter Valkovic, Gabriela Timarova
Article Number: 8
Published online on: 24 October 2025

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Case Report Open Access

Synchronous rectal and endometrial cancer: A case report and literature review

Zhuofan Li, Li Peng, Qing Su, Beige Zong
Article Number: 7
Published online on: 24 October 2025

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Article

Predictive significance of thoracic skeletal muscle nutritional status for radiotherapy survival in elderly patients with esophageal squamous cell carcinoma

Shuqin Liu, Qi Li, Dongmei Luo, Caixia Jia, Dingqiang Peng, Guihong Liu
Article Number: 6
Published online on: 24 October 2025

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Review Open Access

Ribosome‑binding protein 1: A multidimensional regulator of cancer progression and a novel target for precision therapy (Review)

Ho Huang, Jia Ouyang
Article Number: 5
Published online on: 23 October 2025

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Case Report Open Access

Brain metastasis of ovarian cancer >20 years after initial diagnosis: A case report

Chihiro Ishizawa, Kazunari Miyazawa, Misaki Tani, Kazuaki Neriishi, Yukari Kambe, Akira Tsuchiya
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Investigating the roles of microRNAs associated with cancer stem cells, drug resistance, metastasis and recurrence in hepatocellular carcinoma: A systematic review, network analysis and experimental verification

Yuanyuan Jiang, Xiaoning Zhu, Qinghua Peng, Paniz Zarghami Dastjerdi, Mengyun Peng, Ding Zheng, Xiaodong Wang, Yoke Kqueen Cheah, Jing Wang
Article Number: 3
Published online on: 23 October 2025

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Case Report Open Access

Advanced dual primary male breast cancer and lung cancer: A case report and literature review

Xiaoxiao Xing, Junyi Li, Yue Wang, Shiyun Zhang, Jun Li, Yun Wang, Dongpo Zhang, Daixiang Liao
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and induces apoptosis of prostate and bladder cancer cells

Lin Hao, Yan Zhao, Zhi-Gang Li, Hou-Guang He, Qing Liang, Zhi-Guo Zhang, Zhen-Duo Shi, Pei-Ying Zhang, Cong-Hui Han
Article Number: 1
Published online on: 22 October 2025

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February-2026 Volume 31 Issue 2

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Tanshinone IIA targets RNF123 to inhibit non‑small cell lung cancer cell proliferation, migration and invasion via KAT2B‑mediated H3K18ac modification

Yongjie He, Yingxin Zhang, Jiangsheng Zhang, Kaican Cai
Article Number: 69
Published online on: 04 December 2025

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Expression profiling reveals coordinated dysregulation of autophagy‑associated proteins in marginal zone lymphoma and therapeutic implications

Jingshu Ruan, Xin Zhou, Ai Li, Ningning Shan
Article Number: 68
Published online on: 03 December 2025

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Article Open Access

Analysis of the TCRβ repertoire characteristics when combining radiotherapy and immunotherapy in cancer

Xueli Yang, Wujun Wei, Zhihui Feng, Biao Zhang, Yi Liu, Fei Yang, Chong Zhang, Minglin Ou, Songbai Liao, Xianliang Hou
Article Number: 67
Published online on: 03 December 2025

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Identification and validation of critical mitochondrial hub genes for prostate cancer

Sha Liu, Liang Huang, Li Lin, Hong Shan, Yueming Wan
Article Number: 66
Published online on: 03 December 2025

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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

Ruibing Yang, Jiali Gao, Yunyun Cheng, Caihong Lu, Juan Li
Article Number: 65
Published online on: 03 December 2025

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Case Report Open Access

Pregnancy with vitrified oocytes after fertility sparing surgery in a patient with fallopian tube cancer and a BRCA2 mutation: A case report and literature review

Guglielmo Stabile, Stefania Cicogna, Gabriella Zito, Anna Vido, Andrea Romano, Alessandro Mangogna, Luigi Nappi, Giuseppe Ricci
Article Number: 64
Published online on: 02 December 2025

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Retraction Open Access

[Retracted] Clinical significance and effect of Sam68 expression in gastric cancer

Jinzhang Xiao, Qiuhong Wang, Qichang Yang, Hua Wang, Fulin Qiang, Song He, Jin Cai, Lei Yang, Yingying Wang
Article Number: 63
Published online on: 02 December 2025

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Article Open Access

Genome‑wide CRISPR screening identifies CLDN1 as a central node in the anticancer mechanisms of berberine and as a therapeutic target in lung cancer

Xiaogang Wang, Benzhong Mi, Jinfeng Lv, Xin Tang, Jingyu Huang, Fei Liu, Yajing Xing, Xingjian Wen, Yongde Wang, Yadong Zhong
Article Number: 62
Published online on: 01 December 2025

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Article Open Access

Construction of a human epidermal growth factor receptor 2‑related gene risk model for predicting breast cancer prognosis

Limin Huang, Chunhong Xu, Yining Song, Furong Sun, Xuemei Sun, Hanyi Yao, Mingchen Liu, Nan Luo
Article Number: 61
Published online on: 01 December 2025

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Article Open Access

Development of a machine learning model for preoperative prediction of spread through air spaces in resectable 
non‑small cell lung cancer: A single‑center retrospective study

Chong Yang, Guozheng Ding, Bicheng Zhan, Lanlan Xuan, Feifei Cheng, Yanguo Yang
Article Number: 60
Published online on: 01 December 2025

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Integrated diagnostic evaluation of multiple malignant neoplasms via 99mTc‑MDP three‑phase bone imaging: A case report

Jing-Yi Lian, Jian-Lin Lu, Hui-Yu Zheng, Si-Xia Yuan, Jin-Shan Zhang
Article Number: 59
Published online on: 01 December 2025

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Article

Retrospective analysis of the association between monocyte percentage and outcomes in newly diagnosed diffuse large B‑cell lymphoma

Chaoqiang Zheng, Xiaoqin Xin
Article Number: 58
Published online on: 28 November 2025

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Review Open Access

Role of HOXA transcript antisense RNA myeloid‑specific 1 in cancer (Review)

Yipei Jing, Xiaoqi Li, Ye Guo
Article Number: 57
Published online on: 28 November 2025

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Article Open Access

Differential gene expression analysis reveals signaling pathways of proliferation, angiogenesis and metastasis is associated with interferon suppression in advanced hypopharyngeal cancer cells

Chia-Wei Kao, Yen-Ping Yeh, Ting-Wen Chen, Min-Ying Lin, Jyh-Der Leu, Yi-Jang Lee
Article Number: 56
Published online on: 27 November 2025

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Case Report Open Access

Unicentric Castleman disease with paraneoplastic pemphigus and follicular dendritic cell sarcoma: A case report

Yukun Li, Fanchen Zeng, Zeyao Wang, Ganjian Zhao, Qi Zhou
Article Number: 55
Published online on: 27 November 2025

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Article Open Access

CRISPR/Cas9‑mediated claudin‑2 knockout in HCT116 cells reveals its key role in colorectal cancer progression

Rana A. Alghamdi, Maryam H. Al‑zahrani
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

Comparative evaluation of microRNA detection in plasma, urine and liquid‑based cytology for high‑grade cervical intraepithelial neoplasia

Stéphanie Calfa, Ana Julia Aguiar De Freitas, Welinton Hirai, Júlio César Possati‑Resende, Rhafaela Lima Causin, Ricardo Dos Reis, Rui Manuel Reis, Márcia Maria Chiquitelli Marques
Article Number: 53
Published online on: 26 November 2025

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Case Report Open Access

Small intestinal SMARCA4‑deficient undifferentiated carcinoma with intussusception: A case report

Xiaoshan Cai, Shanshan Liu, Linqian Li, Yuming Zhang, Qin Guo, Ze Chen, Meihua Qu, Yubing Wang, Ben Yang, Xianwen Yue
Article Number: 52
Published online on: 26 November 2025

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Article Open Access

SENP5 acts as a downstream target of androgen receptor and contributes to prostate cancer growth

Ximin Chen, Xubo Gong, Jingcheng Zhang, Weiwei Liu
Article Number: 51
Published online on: 26 November 2025

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Retraction Open Access

[Retracted] Scutellarein suppresses Aβ‑induced memory impairment via inhibition of the NF‑κB pathway in vivo and in vitro

Xiao-Wei Huang, Yan Xu, Xin Sui, He Lin, Jia-Ming Xu, Dong Han, Dou-Dan Ye, Guang-Fu Lv, Yue-Xin Liu, Xiao-Bo Qu, Ming-Hua Duan
Article Number: 50
Published online on: 26 November 2025

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Article Open Access

Prognostic analysis and expression patterns of programmed cell death ligand 1 and BRAF V600E in esophageal neuroendocrine carcinoma

Chengcheng Zhang, Li Zheng, Binwen Xu, Guidong Shi, Maoyong Fu
Article Number: 49
Published online on: 25 November 2025

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Article

Evaluating computer‑assisted mandibular reconstruction: Outsourced vs. in‑house approaches

Sho Katsura, Yoshihiro Morita, Ryotaro Kakimoto, Tetsuo Miyamoto, Kana Kashima, Emiko Ogasa, Yoshio Ueno, Ayano Tobe‑Nishimoto, Satoko Kishimoto, Yuka Matsumiya‑Matsumoto, Akinori Takeshita, Kazuhide Matsunaga, Narikazu Uzawa
Article Number: 48
Published online on: 25 November 2025

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Case Report Open Access

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report

Qing Ouyang, Bing Sun, Haodong Sun, Jianing Luo, Zhen Xu, Yuan Ma
Article Number: 47
Published online on: 25 November 2025

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Review Open Access

Exploration of immunotherapy modalities in stage III unresectable non‑small cell lung cancer (Review)

Jiayun Ma, Jun Jiang
Article Number: 46
Published online on: 25 November 2025

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Case Report

Massive breast fat necrosis with invasive breast cancer: A case report

Anjie Zhang, Linfeng Song, Xiyao Yang, Xu Chen, Binlin Tian, Yongzhe Li, Guoyuan Jiang, Lin Jiang
Article Number: 45
Published online on: 25 November 2025

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