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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2025 Volume 30 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Chromophobe renal cell carcinoma with sarcomatoid change: A case report

Ae Ri Ahn, Sang Jae Noh, Young Bum Jeong, Kyoung Min Kim
Article Number: 371
Published online on: 28 May 2025

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Review Open Access

Diagnostic methods for pancreatic cancer and their clinical applications (Review)

Juan Zhao, Jiahuan Wang, Yuanlong Gu, Xiaoyi Huang, Linyou Wang
Article Number: 370
Published online on: 27 May 2025

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Case Report Open Access

Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report

Yun He, Huanfang Fan, Zhihua Du, Dehui Li, Yiting Gu, Zihui Liu
Article Number: 369
Published online on: 27 May 2025

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Review Open Access

Gut microbiome versus thyroid cancer: Association and clinical implications (Review)

Mali Wang, Yuchun Zhu
Article Number: 368
Published online on: 27 May 2025

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Case Report Open Access

Six‑year survival after oral temozolomide maintenance therapy in limited‑stage small cell lung cancer: A case report

Daixi Wu, Yangbo Xu, Chao Wang, Tao Xu, Yuqi Gu, Xiaojia Zhang, Aolin Wang, Huijuan Cui
Article Number: 367
Published online on: 27 May 2025

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Article Open Access

Factors influencing pathological complete response to neoadjuvant chemotherapy in resectable breast cancer: A retrospective study

Jian Kang, Huifen Xiong, Xiaoliu Jiang, Zhaohui Huang, Yonghong Guo, Yali Cao, Jingxian Ding
Article Number: 366
Published online on: 27 May 2025

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Retraction Open Access

[Retracted] Upregulation of miR‑34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC‑7901 cells through inhibition of the PI3K/Akt signaling pathway

Guojun Wang, Guanghui Liu, Yanwei Ye, Yang Fu, Xiefu Zhang
Article Number: 365
Published online on: 27 May 2025

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Article Open Access

Changes in thyroid hormone levels indicate immunotherapy efficacy in gastric cancer

Min Xiao, Lan Liu Qian, Qiu Zhao, Jian Ma, Qianxiao Li, Qian Liu, Zhiyan Bi
Article Number: 364
Published online on: 26 May 2025

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Article Open Access

Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis Corrigendum in /10.3892/ol.2026.15473

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 363
Published online on: 23 May 2025

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Article Open Access

Identification and validation of prognostic models and tumor microenvironment infiltration characteristics for tRNA modification regulators in clear cell renal cell carcinoma

Xu Zhu, Cheng Shen, Wei Zhang, Yuanfei Ji, Siyang Xu, Bing Zheng, Zhan Chen
Article Number: 362
Published online on: 22 May 2025

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Article Open Access

OSW‑1 inhibits tumor cell proliferation and migration via uncoupling protein 2 in hepatocellular carcinoma

Kaiwen Shen, Xinglin Jin
Article Number: 361
Published online on: 22 May 2025

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Article Open Access

Application of serum anti‑ENO1 and anti‑SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer

Satoshi Yajima, Masaaki Ito, Takashi Suzuki, Yoko Oshima, Makoto Sumazaki, Fumiaki Shiratori, Hirotaka Takizawa, Shu-Yang Li, Bo-Shi Zhang, Yoichi Yoshida, Tomoo Matsutani, Takaki Hiwasa, Hideaki Shimada
Article Number: 360
Published online on: 22 May 2025

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Article Open Access

Prognosis and influencing factors of patients with different lymph node statuses after pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer

Jianxi Zhou, Yunchuan Sun, Li Xiao, Hongling Lu, Xiaoming Yin, Yaru Kong, Yiyan Zhang, Wei Guo, Yingnan Zhou
Article Number: 359
Published online on: 22 May 2025

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Case Report

Malignant mesothelioma with a novel BAP1 germline frameshift mutation treated with dual immune checkpoint inhibitors: A case report

Na Zhou, Mingying Wu, Chenyu Wang, Mingming Yuan, Yuejuan Cheng, Huanwen Wu, Xin Gao, Shuangni Yu, Lin Zhao
Article Number: 358
Published online on: 21 May 2025

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Article Open Access

In vitro and in silico investigation of the critical role of GABAB receptor activation in human breast cancer and its natural agonists

Mustafa Hussein Ali, Ziyad Tariq Muhseen, Zahraa Yousif Al-Hajjaj, Hussein Hazim Al-Ghanimi, Abdulrahman Alshammari, Norah Abdullah Albekairi
Article Number: 357
Published online on: 21 May 2025

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Article Open Access

Integration of dual‑source dual‑energy CT quantitative parameters and ultrasound image features: A diagnostic method for extraglandular invasion of papillary thyroid carcinoma

Muhammad Asad Iqbal, Nida Fatima Moazzam, Hui Zhou, Jie Hou, Hui Sun, Donggang Pan, Xian Wang
Article Number: 356
Published online on: 21 May 2025

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Correction Open Access

[Corrigendum] Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation

Lina Qiao, Jianbao Zheng, Xianzhen Jin, Guangbing Wei, Guanghui Wang, Xuejun Sun, Xuqi Li
Article Number: 355
Published online on: 21 May 2025

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Review Open Access

Evolving role of deubiquitinating enzymes in oral cancer (Review)

Zidi Wang, Siyuan Cheng, Jianhui Wei, Jiandong Hu, Fenge Li, Wenhua Yang
Article Number: 354
Published online on: 19 May 2025

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Article Open Access

Role of the SPI1/CDKN2A/p53 signaling pathway in cuproptosis of lung adenocarcinoma cells

Jiayue An, Wei Song, Qin Wang, Boyu Tan, Xuan Fei, Ruoxi Wang, Siyan Li, Xiyu Lu, Youjie Li, Ning Xie
Article Number: 353
Published online on: 19 May 2025

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Case Report Open Access

Rechallenge of anti‑PD‑1 antibody combined with chemotherapy shows promising efficacy in the treatment of advanced metastatic hepatocellular carcinoma: A case report

Xiang Tan, Le Kang, Hao Chen, Xingyan Liu, Chi Du
Article Number: 352
Published online on: 19 May 2025

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Retraction Open Access

[Retracted] Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao
Article Number: 351
Published online on: 19 May 2025

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Article Open Access

Comprehensive analysis of a palmitoylation‑related prognostic signature in colorectal cancer: Implications for immune therapy and personalized treatment

Xiaokang Wang, Jian Li, Zi Wang, Qingyun Wu
Article Number: 350
Published online on: 16 May 2025

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Case Report Open Access

Pancreatic metastasis from cervical cancer: A case report and literature review

Hailing Liao, Xiaoyan Chang, Xiaorong Hou, Fuquan Zhang
Article Number: 349
Published online on: 16 May 2025

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Article Open Access

Efficacy and safety of BCG and immune checkpoint inhibitors in non‑muscle invasive bladder cancer: A meta‑analysis with exploratory chemotherapy comparisons

Mohamed Mohamoud Adan, Xudong Mao, Lifeng Ding, Khalid Mohamoud Abdullahi, Gonghui Li
Article Number: 348
Published online on: 16 May 2025

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Case Report Open Access

Arterial perfusion chemoembolization combined with iodine‑125 seeds for stage IIB osteosarcoma: A case report

Linhao Ran, Fan Li, Li Jiang, Li Yang, Ying Liu
Article Number: 347
Published online on: 15 May 2025

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Article Open Access

Long‑term follow‑up outcomes of intraoperative radiotherapy for breast‑conserving treatment in early breast cancer: A retrospective cohort study

Xiaofan Xu, Lu Wang, Yuanyuan Cao, Jingyi Wang, Jie Yao, Liqun Huo, Yuqing Song, Wei Ding, Jun Gu, Qiurong Li
Article Number: 346
Published online on: 15 May 2025

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Article Open Access

Utility of the CPS + EG score with real‑life data in patients with breast cancer undergoing neoadjuvant chemotherapy

Ezgi Yildiz Yurekli, Seval Akay, Olcun Umit Unal
Article Number: 345
Published online on: 15 May 2025

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Case Report Open Access

Fan beam computed tomography‑guided online adaptive external radiotherapy for cervical cancer achieves pathological complete response: A case report

Haibo Peng, Ningyue Xu, Dong Gao, Huigang Tan, Tao Ren
Article Number: 344
Published online on: 14 May 2025

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Case Report Open Access

Spinal cord metastasis in a long‑term survivor of primary malignant glioblastoma: A case report 

Pengwei Hou, Meiyan Liu, Ziqi Li, Mingfa Cai, Chenzhu Cai
Article Number: 343
Published online on: 14 May 2025

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Review Open Access

Combination of radiotherapy and ICIs in advanced hepatocellular carcinoma: A systematic review of current evidence and future prospects (Review)

Cheng Ma, Xinlin Yu, Xialin Zhang, Lihong Su, Ou Jiang, Ran Cui
Article Number: 342
Published online on: 14 May 2025

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Article Open Access

Application and clinical translational value of a predictive model based on N7‑methylguanosine‑related long non‑coding RNAs in cervical squamous cell carcinoma

Jun Zhang, Yingna Bao, Zhilong Yu, Yu Lin
Article Number: 341
Published online on: 14 May 2025

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Case Report Open Access

Cerebral metastasis from anal squamous cell carcinoma: A case report and literature review

Elena Andreea Popa, Vanesa Marisa Tomatis, Esther Quick, Paul Stephen Mitchell, Chrisovalantis Tsimiklis, Annika Reann Mascarenhas
Article Number: 340
Published online on: 13 May 2025

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Article Open Access

AMIGO2 expression at the invasive front of bladder cancer predicts recurrence‑free and overall survival after radical cystectomy

Atsushi Yamamoto, Runa Izutsu, Heekyung Seong, Ryutaro Shimizu, Ryoma Nishikawa, Yusuke Kimura, Noriya Yamaguchi, Shuichi Morizane, Katsuya Hikita, Masashi Honda, Atsushi Takenaka, Futoshi Okada
Article Number: 339
Published online on: 13 May 2025

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Case Report Open Access

Primary pulmonary malignant melanoma with H3K27Me3 loss: A case report

Houqiang Li, Lanqing Zheng, Xunbin Yu, Linfeng Chen, Shanshan Lv, Xin Chen
Article Number: 338
Published online on: 13 May 2025

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Case Report Open Access

Successful robot‑assisted minimally invasive surgery for scirrhous gastric conduit cancer after esophagectomy: A case report

Koichi Okamoto, Yuta Sannomiya, Koki Furuse, Kaori Maruyama, Hisashi Nishiki, Akifumi Hashimoto, Daisuke Kaida, Takashi Miyata, Toshikatsu Tsuji, Hideto Fujita, Noriyuki Inaki, Shinichi Kinami, Itasu Ninomiya, Hiroyuki Takamura
Article Number: 337
Published online on: 12 May 2025

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Retraction Open Access

[Retracted] Metformin mitigates PLCε gene expression and modulates the Notch1/Hes and androgen receptor signaling pathways in castration‑resistant prostate cancer xenograft models

Qi Li, Ke Xu, Jianguo Tian, Zhicheng Lu, Jianming Pu
Article Number: 336
Published online on: 12 May 2025

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Article Open Access

Retroperitoneal growth of high‑grade serous ovarian carcinoma: A case report

Pengnan Hu, Weizhou Pan, Jun Yu, Hua Mi
Article Number: 335
Published online on: 09 May 2025

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Article Open Access

Establishment and evaluation of an automatic multi‑sequence MRI segmentation model of primary central nervous system lymphoma based on the nnU‑Net deep learning network method

Tao Wang, Xingru Tang, Jun Du, Yongqian Jia, Weiwei Mou, Guang Lu
Article Number: 334
Published online on: 09 May 2025

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Case Report

Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report 

Binh Van Pham, Duy Duc Nguyen, Manh Dai Tran, Thanh Duy Nguyen, An Duc Thai, Binh Tien Nguyen, Ky Van Le, Hoa Thi Thanh Nguyen
Article Number: 333
Published online on: 08 May 2025

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Review

Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)

Xing Xu, Xue Zhang, Yang Zhao, Xiaoyang Zhang, Hongfang Tuo
Article Number: 332
Published online on: 07 May 2025

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Case Report Open Access

Breast cancer metastasis to the nasopharynx: A case report

Yandong Bian, Chen Song, Yuhui Nie, Xin Shen, Fu Hui, Guohua Yu
Article Number: 331
Published online on: 07 May 2025

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Article Open Access

Distinguishing acute leukemia subtypes: The role of hsa_circ_0012152 and hsa_circ_0020093 in peripheral blood

Qiming Ying, Dingfeng Lv, Ying Chen, Qitian Mu
Article Number: 330
Published online on: 07 May 2025

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Retraction Open Access

[Retracted] lncRNA‑CD160 decreases the immunity of CD8+ T cells through epigenetic mechanisms in hepatitis B virus infection

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 329
Published online on: 06 May 2025

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Article Open Access

Efficacy and safety of furmonertinib in patients with EGFR‑mutant advanced lung adenocarcinoma after failure of multiple lines of therapy: A single‑center retrospective study

Yumin Zheng, Xingyu Lu, Huijing Dong, Jia Li, Yulei Shen, Zhening Liu, Huijuan Cui
Article Number: 328
Published online on: 02 May 2025

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Article Open Access

Prophylactic cerebral irradiation sensitizes relapsed sensitive small cell lung cancer to temozolomide: A retrospective cohort study

Dan He, Shuxia Wei, Fenghao Geng, Lintao Li, Fengyu Li, Yanli Ge, Ruichang Lv, Weiwei Li, Zhijun Hao, Fengdi Jiang, Chao Meng, Shun Lu, Shuyu Zhang
Article Number: 327
Published online on: 02 May 2025

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Case Report Open Access

Sintilimab‑induced acute erosive hemorrhagic gastritis as an adverse reaction of third‑line therapy in a nasopharyngeal carcinoma patient: A case report

Wenqiang Tang, Yun Lv, Xiyue Yang, Kunyuan Gan, Gang Feng, Jie Li, Lu Ni, Yuxi Bai, Xiaobo Du, Feng Gao
Article Number: 326
Published online on: 02 May 2025

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Review Open Access

Application of multivalent aptamers in tumor diagnosis, analysis and therapy (Review)

Hongyue Zeng, Wenjing Zeng, Yaoyao Liang
Article Number: 325
Published online on: 02 May 2025

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Article

AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells

Gulsum Altiparmak-Ulbegi, Gozde Hasbal-Celikok, Pinar Aksoy-Sagirli
Article Number: 324
Published online on: 02 May 2025

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Article Open Access

Prognostic value of the pretreatment Glasgow prognostic score or modified Glasgow prognostic score in patients with advanced cancer receiving immune checkpoint inhibitors: A systematic review and meta‑analysis

Lianghui Zhang, Lili Lin, Jie Ni, Tao Ling, Lingli Huang
Article Number: 323
Published online on: 02 May 2025

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Article Open Access

Establishment and validation of a clinical prediction model for colorectal adenoma risk factors

Dong-Lin Li, Ling-Ling Ma, Zhong-An Guan, Yu-Xin Zhao, Chuan Jiang
Article Number: 322
Published online on: 02 May 2025

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Case Report Open Access

Pulmonary pleomorphic carcinoma associated with cystic airspace and recurrent spontaneous pneumothorax: A case report

Qiangsheng Li, Jing Zhang, Youjie Gong, Xudong Wan, Song Zhang, Zhongwang Li, Jun Liu
Article Number: 321
Published online on: 02 May 2025

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Case Report Open Access

Composite B‑cell lymphoma and extranodal natural killer/T‑cell lymphoma presenting with distinct clone evolution and tumor microenvironment: A report of two cases

Qiuyue Wen, Qiuhui Li, Wei Yang, Xiaona Chang, Fang Zhu, Huaxiong Pan, Liling Zhang
Article Number: 320
Published online on: 02 May 2025

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Journal Cover
July-2026 Volume 32 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Clinicopathological characterization of cervical squamous cell carcinoma with PIK3CA hotspot mutation: A single‑institution study

Jason Murray, Harsimar Kaur, Colton Smith, Annie A. Wu, Lee Shu-Fune Wu, Ya-Chea Tsai, Chien-Fu Hung, T.-C. Wu, Deyin Xing
Article Number: 321
Published online on: 02 June 2026

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Correction Open Access

[Corrigendum] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 320
Published online on: 02 June 2026

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Case Report Open Access

Immune checkpoint inhibitors for invasive mucinous adenocarcinoma: A case series

Tatsuya Kato, Takahiro Mitsumura, Eiyu Tsuboi, Hiroshi Nakahama, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 319
Published online on: 29 May 2026

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Article Open Access

Development and validation of a prognostic nomogram incorporating preoperative NLR, CEA and CA19‑9 for overall survival in colorectal cancer

Bo Shi, Haoran Guo, Junjie Chen, Zhijian Peng, Suo Wang, Guoliang Chen, Qingliang Tai, Xinyu Shi, Songbing He
Article Number: 318
Published online on: 29 May 2026

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Article

Survival prediction in stage II/III rectal cancer: Role of immune‑inflammatory biomarkers post neoadjuvant chemoradiotherapy

Bingjie Li, Taotao Huang, Shijing Xu, Yuhuan Ye, Yong Liu, Xiaoyu Wang, Yongsheng Wang
Article Number: 317
Published online on: 29 May 2026

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Article Open Access

LATS2 expression differences in lung adenocarcinoma and lung squamous cell carcinoma analyzed using bioinformatics and experimental approaches

Zhen Zhang, Shaoyan Zhang, Yalai Xu, Changyu Zhang, Xudong Zhang
Article Number: 316
Published online on: 28 May 2026

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Expression of Concern Open Access

[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial‑mesenchymal transition by forming a positive feedback loop with c‑Myc

Yang Tang, Fang Ji
Article Number: 315
Published online on: 26 May 2026

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Article Open Access

Lectin‑captured plasma microRNAs predict response and survival in patients with non‑small cell lung cancer treated with nivolumab

Eiji Narusawa, Yukiko Nakano, Seshiru Nakazawa, Kanji Hori, Yoichi Ohtaki, Natsuko Kawatani, Tomohiro Yazawa, Ryohei Yoshikawa, Kazuki Numajiri, Ryo Kuriyama, Hiroshi Kurokawa, Yoshihiro Taguchi, Seyed Mostafa Mostafavi Zadeh, Haruka Okami, Takuya Shiraishi, Nobuhiro Nakazawa, Takamichi Igarashi, Kyoichi Kaira, Hiroshi Saeki, Ken Shirabe, Takehiko Yokobori
Article Number: 314
Published online on: 25 May 2026

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Review

Cancer stem cells and their molecular signaling mechanisms in tongue squamous cell carcinoma (Review)

Xuqiang Guo, Xuan Zhou, Wen Ran, Qiao Zhu, Wei Chen, Chengcheng Ma
Article Number: 313
Published online on: 25 May 2026

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Article Open Access

Pathological response and tumor regression grading following neoadjuvant chemo‑immunotherapy and chemotherapy in resectable non‑small cell lung cancer

Özge Kaya Korkmaz, Yaren Sari Çataldaş, Nazlican Saltik Barel, Mehmet Büyükevli
Article Number: 312
Published online on: 22 May 2026

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Article Open Access

D‑salicin induces oxidative stress‑mediated ERK1/2 suppression and apoptosis in endometrial cancer cells

Neziha Senem Ari, Ayşe Çakir Gündoğdu
Article Number: 311
Published online on: 22 May 2026

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Article Open Access

Decoding the role of polyamine metabolism in lung adenocarcinoma prognosis: A triangulated approach combining transcriptome, single‑cell and Mendelian randomization analyses

Hua Yang, Lemeng Zhang, Jianhua Chen, Junjie Zhang
Article Number: 310
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] Antitumor effects of dioscin in A431 cells via adjusting ATM/p53‑mediated cell apoptosis, DNA damage and migration

Peng Wang, Chun Wang, Chunying Liu
Article Number: 309
Published online on: 21 May 2026

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Review Open Access

Targeting non‑small cell lung cancer: Molecular mechanisms and clinical studies (Review)

Ying Luo, Guofang Yin, Xiaoqin Luo, Yue Liu, Kaiyu Jin, Zhiguo Wang
Article Number: 308
Published online on: 20 May 2026

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Article Open Access

Histopathological changes in primary extramammary Paget disease with emphasis on syringomatous structures and syringocystadenocarcinoma papilliferum in situ‑like changes

Yutaro Fukuma, Mitsuaki Ishida, Yoshinobu Hirose
Article Number: 307
Published online on: 20 May 2026

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Case Report Open Access

Durable response to selpercatinib in HOOK3‑RET fusion positive, α‑fetoprotein producing metastatic pancreatic ductal adenocarcinoma with intestinal‑type differentiation

Harsahib Singh Sandhu, Aparna Natarajan, Smiley Joshi
Article Number: 306
Published online on: 20 May 2026

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Correction Open Access

[Corrigendum] PVT1 promotes resistance to 5‑FU in colon cancer via the miR‑486‑5p/CDK4 axis

Zhuhe Luo, Ruijun Chen, Shen Hu, Xibin Huang, Zhenyi Huang
Article Number: 305
Published online on: 20 May 2026

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Case Report Open Access

Pelvic schwannoma misdiagnosed as colorectal cancer metastasis and the corresponding diagnostic lessons: A report of two cases

Shilong Wang, Kaixiang Zhang, Xiangwu Lin, Feilai Xie, Jian Yang, Jie Li
Article Number: 304
Published online on: 19 May 2026

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Case Report

Multidetector computed tomography detection of perineural infiltration around the superior mesenteric artery in intrahepatic cholangiocarcinoma: A case report

Myeong Hun Oh, Byeong Gwan Noh, Hyung Il Seo, Young Mok Park, Suk Kim, Nam Kyung Lee, Seung Baek Hong
Article Number: 303
Published online on: 19 May 2026

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Review Open Access

Clinical implications of lactylation modification in digestive system tumors (Review)

Lin Pan, Fengye Liu, Wenjing Yu
Article Number: 302
Published online on: 19 May 2026

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Article Open Access

Rare BRCA1 c.3418_3419insTGACTACT:p.S1140Mfs*18 germline mutation in a family with breast and ovarian cancer

Chao Zhai, Long Jia, Chaoyang Wang, Liang Chen, Tuo Han, Dong Xiao
Article Number: 301
Published online on: 19 May 2026

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Expression of Concern Open Access

[Expression of Concern] miR‑148a inhibits cell proliferation and migration through targeting ErbB3 in colorectal cancer

Wei Zhao, Jianbao Zheng, Guangbing Wei, Kui Yang, Guanghui Wang, Xuejun Sun
Article Number: 300
Published online on: 19 May 2026

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Article Open Access

Prognostic significance of squamous differentiation in pT2N0 urothelial bladder cancer

Alper Coskun, Ahmet Bilgehan Sahin, Selva Kabul, Mehmet Emin Dagtekin, Seda Sali, Buket Erkan Ozmarasali, Adem Deligonul, Erdem Cubukcu, Meral Kurt, Gursel Savci, Turkkan Evrensel, Ismet Yavascaoglu
Article Number: 299
Published online on: 18 May 2026

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Article

Jaceosidin inhibits cell viability and induces apoptosis in non‑small cell lung cancer by inhibiting the Ras/Raf/MEK/ERK and Akt pathways

Xiaodie Cao, Chong Ma, Xin Wang, Cui Wang, Lanlin Shen, Jingru Wei, Rongmin Yang, Yan Li, Xu He, Li Chen
Article Number: 298
Published online on: 18 May 2026

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Review Open Access

Ubiquitination and N6‑methyladenosine in cancer: Convergent regulation of oncogenic signaling pathways (Review)

Hailong Li, Xuelin Lu
Article Number: 297
Published online on: 18 May 2026

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Correction Open Access

[Corrigendum] TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells

Chao Zhou, Jie Ma, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Yongjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao
Article Number: 296
Published online on: 15 May 2026

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Case Report Open Access

Primary endometrioid adenocarcinoma of the vagina after total hysterectomy for adenomyosis: A case report

Tingting Wang, Xin Li, Liping Chen, Jing Zhang, Lina Peng, Haitao Yang
Article Number: 295
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Tanshinol upregulates the expression of aquaporin 5 in lung tissue of rats with sepsis

Jianfeng Xu, Lei Yang, Liang Dong
Article Number: 294
Published online on: 14 May 2026

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Article Open Access

Weekly cisplatin and nab‑paclitaxel neoadjuvant chemoradiotherapy increases pathological complete response in locally advanced esophageal squamous cell carcinoma: A real‑world study

Li Li, Xuquan Jing, Jiling Niu, Yan Yi, Yujie Wang, Ke Zhao, Jingyu Luo, Jinming Yu, Hui Zhu
Article Number: 293
Published online on: 13 May 2026

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Article Open Access

Gastrointestinal cancer with indeterminate 18F‑FDG PET/CT findings: Diagnostic efficacy analysis of 68Ga‑FAPI‑04 PET/MRI

Jingxuan Miao, Yifei Xu, Feng Qiao, Ni Chen, Muhammad Imran Khan, Ye Zhao, Hui Wang
Article Number: 292
Published online on: 13 May 2026

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Article Open Access

Breaking senescence restriction: MAFK‑AREG axis promotes NSCLC cells to resist doxorubicin

Ningning Fan, Guanying Liang, Jiayue Shao, Qi Wang, Lu Fu
Article Number: 291
Published online on: 13 May 2026

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Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Case Report Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Case Report Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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August-2026 Volume 32 Issue 2

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Impact Factor: 2.2

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report

Initial chemotherapy decreases transfusion dependence and enables definitive therapy in metastatic thymoma complicated by pure red cell aplasia: A case report

Nobuhito Hara, Rika Sasaki, Yoshiki Kojitani, Yumi Yoshii, Masahide Ota, Shunsuke Okazaki, Shinichi Ochi, Ryo Miyata, Masatsugu Hamaji, Sayaka Ando, Maiko Takeda, Akihiko Yoshizawa, Masayuki Takeda
Article Number: 354
Published online on: 16 June 2026

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Article Open Access

Bioinformatics analysis of proteins in the complement and coagulation cascades in colon cancer: Discovering the potential biomarker SERPINA1

Da Lian, Daixin Hou, Kunpeng Liu, Hao Jiang, Pengyu Xie
Article Number: 353
Published online on: 16 June 2026

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Article

Circulating miRNA‑30a is associated with favorable therapeutic outcome in patients with gastric cancer treated with neoadjuvant chemotherapy

Vasileia Kokala‑dimitropoulou, Alexandros Mitrousias, Athanasios Tsiatouras, Aigli Vakrakou, Pantelis T. Antonakis, Manousos M. Konstantoulakis
Article Number: 352
Published online on: 16 June 2026

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Case Report Open Access

Salvage robotic‑assisted subtotal esophagectomy after chemoradiotherapy for unresectable locally advanced esophageal sarcoma: A case report

Masaaki Yamamoto, Atsushi Takeno, Kiyoshi Mori, Yumiko Hirose, Shinji Tokuyama, Yuki Matsui, Reishi Toshiyama, Kenji Kawai, Yusuke Takahashi, Kenji Sakai, Naoki Hama, Takeshi Kato, Koji Takami, Motohiro Hirao
Article Number: 351
Published online on: 16 June 2026

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Article Open Access

A prognostic senescence‑related long non‑coding RNA signature identifies cold and hot tumors of stomach adenocarcinoma

Chenxi He, Fanting Kong, Baojuan Han, Litao Lv, Xiaoling Wang, Xiangguang Kong, Qingjiao Zeng, Peipei Zhou
Article Number: 350
Published online on: 16 June 2026

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Article Open Access

Double vs. single autologous stem cell transplantation in patients with multiple myeloma and high‑risk factors: A systematic review and meta‑analysis

Sibei Qin, Yusi Liu, Peng Zhang, Qionglin Zhou, Xiayan Xu, Danbo Liu, Fang Du, Jiao Chen, Lingyun Zhou, Weiling Cao, Haifei Chen
Article Number: 349
Published online on: 16 June 2026

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Retraction Open Access

[Retracted] Long non‑coding RNA CCAT2 promotes prostate cancer cell proliferation and invasion by regulating the Wnt/β‑catenin signaling pathway

Peng He, Guoguang Xiong, Wei Guo, Guanjun Jiang, Yun Li, Hao Li
Article Number: 348
Published online on: 15 June 2026

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Review Open Access

Advantages and research progress of three‑dimensional culture systems for lung cancer drug screening (Review)

Yihe Tian, Hai Liu, Minhong Zhang, Aiping Cui, Hao Chen, Lei Shi, Junyao Zhu, Mingchun Li, Biao Wang, Hao Huang, Jianqiong Yang
Article Number: 347
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑182 promotes epithelial‑mesenchymal transition by targeting FOXN3 in gallbladder cancer

Jianhong Zhang, Zeming Hu, Chao Wen, Qicheng Liao, Baoqing He, Jing Peng, Xin Tang, Zhixi Chen, Yuankang Xie
Article Number: 346
Published online on: 12 June 2026

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Article Open Access

Lactate‑to‑albumin ratio as an independent predictor of short‑ and long‑term mortality in ICU patients with malignant tumors: A retrospective cohort study

Jingchao Bai, Yihan Xu, Ke Wang, Xin Fu
Article Number: 345
Published online on: 12 June 2026

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Case Report

Long‑term survival with tocilizumab treatment for tislelizumab‑related pneumonitis in a patient with non‑small cell lung cancer: A case report

Lan Yu, Qing-Ming Guo, Li Liu, Yu Wang, Fei Chen, Xiao-Tao Zhang
Article Number: 344
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration

Yanting Duan, Bo Hu, Chunxia Qiao, Xinying Li, Jing Wang, Hao Liu, Tingting Zhou, Beifen Shen, Ming Lv, Jiannan Feng
Article Number: 343
Published online on: 11 June 2026

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Review

Spatiotemporal heterogeneity in non‑small cell lung cancer: A paradigm shift from characterization to dynamic management (Review)

Li Cao, Wei Zhang
Article Number: 342
Published online on: 11 June 2026

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Article Open Access

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer

Yuxiu Huang, Kang Kang, Qian Zhuo, Qianqian Ma, Yujie Xue, Yaning Zhu, Mingde Huang
Article Number: 341
Published online on: 11 June 2026

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Case Report Open Access

Diffuse peritoneal mesothelioma presenting with the appearance of mesenteric panniculitis: A case report

Yunfeng Chen, Qiong Fu, Jialing Xu, Rong Wang, Yongxiang Mo, Yuan Liu
Article Number: 340
Published online on: 11 June 2026

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Article Open Access

Construction and validation of a predictive model of pathological complete response combined with MRI and tumor indicators for HER2‑positive breast cancer after neoadjuvant targeted therapy

Keying Zhu, Zeying Li, Jiaqian Liao, Changan Wang, Rong Guo, Yiyin Tang, Shaoqiang Zhou, Yingying Ding, Dedian Chen, Jiankui Wang, Jianyun Nie, Sheng Huang
Article Number: 339
Published online on: 11 June 2026

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Article Open Access

Tanshinone IIA suppresses cancer metastasis by modulating tumor cell‑platelet‑endothelial cell interactions

Judan Xu, Lin Luo, Feiyang Li, Siying Wang, Chengbin Fu, Guihua Wang, Yanhong Wang, Yusheng Lu
Article Number: 338
Published online on: 11 June 2026

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Article Open Access

RTA‑408 induces JNK‑dependent apoptosis and autophagy in breast cancer cells

Yu-Jen Chen, Hung-Pei Tsai, Mei-Yin Chen, I-Hsiang Chen, Wei-Chieh Chen, Tzu-Ting Tseng, Chen-Yu Wang, Jia-Hau Lee
Article Number: 337
Published online on: 11 June 2026

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Case Report Open Access

Vanishing liver metastases in pancreatic cancer: A case report

Evangelia Florou, Paul Ross, Parthi Srinivasan, Andreas Prachalias
Article Number: 336
Published online on: 11 June 2026

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Case Report Open Access

Long survival of PD‑L1‑positive mediastinal sarcomatoid carcinoma after immunotherapy and anti‑angiogenic target therapy: A case report

Shuling Wu, Danping Wang, Qiong Fu, Yingying Ding
Article Number: 335
Published online on: 11 June 2026

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Case Report

Primary malignant melanoma of the common bile duct: An unexpected finding at pancreaticoduodenectomy: A case report

Evangelia Florou, Hamad Almakinzy, Yoh Zen, Parthi Srinivasan, Andreas Prachalias
Article Number: 334
Published online on: 11 June 2026

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Correction Open Access

[Corrigendum] Imatinib mesylate and nilotinib decrease synthesis of bone matrix in vitro

Lysann Michaela Kroschwald, Osephine Tabea Tauer, Sonja Ingrid Kroschwald, Meinolf Suttorp, Anne Wiedenfeld, Stefan Beissert, Andrea Bauer, Martina Rauner
Article Number: 333
Published online on: 10 June 2026

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Retraction Open Access

[Retracted] Combined application of Embelin and tumor necrosis factor‑related apoptosis‑inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase‑induced apoptosis

Hao Qian, Yao Chen, Tao Huang, Tiemin Liu, Xiucheng Li, Guangjian Jiang, Wei Zhang, Shuo Cheng, Pengcheng Li
Article Number: 332
Published online on: 08 June 2026

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Article Open Access

Cepharanthine suppresses lung adenocarcinoma through targeting glutathione peroxidase 4

Ruoxue Cao, Sun Kang, Kun Wang, Yan Wang, Minghui Li, Qian Liu, Ying Zhang, Mei Fu
Article Number: 331
Published online on: 08 June 2026

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Case Report Open Access

Adrenal lymphoma with hypertension: A report of three cases

Kunlei Tan, Zhijun Han, Yali Zhou, Miduo Tan, Lei Chen, Yinchun Deng
Article Number: 330
Published online on: 05 June 2026

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Case Report

Undifferentiated pelvic sarcoma 5 years post‑radiochemotherapy for rectal adenocarcinoma: A case report

Yang Yang, Yubin Long
Article Number: 329
Published online on: 05 June 2026

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Case Report Open Access

Locally advanced breast cancer in an elderly male with end‑stage renal disease: A case report

Mengfan Chen, Ming Feng, Xiaoyu Li, Huanhuan Wang, Ke Hong, Chang Yao
Article Number: 328
Published online on: 05 June 2026

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Case Report

Warm autoimmune hemolytic anemia following definitive chemoradiotherapy for cervical cancer: A case report

Yuanyuan Kong, Liangxue Zhu, Yuelan Xiao
Article Number: 327
Published online on: 05 June 2026

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Article Open Access

A cross‑platform transcriptomic risk score integrating LymphoMAP microenvironment archetypes and immune evasion‑associated programs in diffuse large B‑cell lymphoma

Xiaochang Chen, Jin Zhang, Shenhe Jin, Luqiao Wang, Ye Zhang
Article Number: 326
Published online on: 03 June 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of fibroblast co‑culture on the proliferation, viability and drug response of colon cancer cells

Byumseok Koh, Hyojin Jeon, Dahee Kim, Dukjin Kang, Kwang Rok Kim
Article Number: 325
Published online on: 03 June 2026

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Review

Biological and pathogenic roles of major genes harbored in intrachromosomal amplification of chromosome 21 in childhood acute lymphoblastic leukemia (Review)

Conrado Emilio Uría‑Gómez, Hugo Mendieta‑Zerón, Jazmín Arteaga‑Vázquez, Antonio Sandoval‑Cabrera
Article Number: 323
Published online on: 03 June 2026

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Article Open Access

IL‑37 drives temozolomide resistance in glioblastoma via MAPK pathway activation

Yu Wang, Ying Liu, Jingyi Wang, Wei Rong, Xue Song
Article Number: 322
Published online on: 03 June 2026

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