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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2025 Volume 30 Issue 1

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Chromophobe renal cell carcinoma with sarcomatoid change: A case report

Ae Ri Ahn, Sang Jae Noh, Young Bum Jeong, Kyoung Min Kim
Article Number: 371
Published online on: 28 May 2025

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Review Open Access

Diagnostic methods for pancreatic cancer and their clinical applications (Review)

Juan Zhao, Jiahuan Wang, Yuanlong Gu, Xiaoyi Huang, Linyou Wang
Article Number: 370
Published online on: 27 May 2025

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Case Report Open Access

Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report

Yun He, Huanfang Fan, Zhihua Du, Dehui Li, Yiting Gu, Zihui Liu
Article Number: 369
Published online on: 27 May 2025

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Review Open Access

Gut microbiome versus thyroid cancer: Association and clinical implications (Review)

Mali Wang, Yuchun Zhu
Article Number: 368
Published online on: 27 May 2025

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Case Report Open Access

Six‑year survival after oral temozolomide maintenance therapy in limited‑stage small cell lung cancer: A case report

Daixi Wu, Yangbo Xu, Chao Wang, Tao Xu, Yuqi Gu, Xiaojia Zhang, Aolin Wang, Huijuan Cui
Article Number: 367
Published online on: 27 May 2025

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Article Open Access

Factors influencing pathological complete response to neoadjuvant chemotherapy in resectable breast cancer: A retrospective study

Jian Kang, Huifen Xiong, Xiaoliu Jiang, Zhaohui Huang, Yonghong Guo, Yali Cao, Jingxian Ding
Article Number: 366
Published online on: 27 May 2025

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Retraction Open Access

[Retracted] Upregulation of miR‑34a by diallyl disulfide suppresses invasion and induces apoptosis in SGC‑7901 cells through inhibition of the PI3K/Akt signaling pathway

Guojun Wang, Guanghui Liu, Yanwei Ye, Yang Fu, Xiefu Zhang
Article Number: 365
Published online on: 27 May 2025

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Article Open Access

Changes in thyroid hormone levels indicate immunotherapy efficacy in gastric cancer

Min Xiao, Lan Liu Qian, Qiu Zhao, Jian Ma, Qianxiao Li, Qian Liu, Zhiyan Bi
Article Number: 364
Published online on: 26 May 2025

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Article Open Access

Efficacy of transarterial chemoembolization‑hepatic arterial infusion chemotherapy combined with targeted therapy and immunotherapy in hepatocellular carcinoma with portal vein tumor thrombosis Corrigendum in /10.3892/ol.2026.15473

Xunbo Hou, Qiannan Xu, Linan Yin, Huiwen Wang, Juan Wu, Bowen Liu, Dongfeng He, Ruibao Liu
Article Number: 363
Published online on: 23 May 2025

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Article Open Access

Identification and validation of prognostic models and tumor microenvironment infiltration characteristics for tRNA modification regulators in clear cell renal cell carcinoma

Xu Zhu, Cheng Shen, Wei Zhang, Yuanfei Ji, Siyang Xu, Bing Zheng, Zhan Chen
Article Number: 362
Published online on: 22 May 2025

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Article Open Access

OSW‑1 inhibits tumor cell proliferation and migration via uncoupling protein 2 in hepatocellular carcinoma

Kaiwen Shen, Xinglin Jin
Article Number: 361
Published online on: 22 May 2025

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Article Open Access

Application of serum anti‑ENO1 and anti‑SSNA1 antibody biomarkers in predicting the prognosis of gastric cancer

Satoshi Yajima, Masaaki Ito, Takashi Suzuki, Yoko Oshima, Makoto Sumazaki, Fumiaki Shiratori, Hirotaka Takizawa, Shu-Yang Li, Bo-Shi Zhang, Yoichi Yoshida, Tomoo Matsutani, Takaki Hiwasa, Hideaki Shimada
Article Number: 360
Published online on: 22 May 2025

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Article Open Access

Prognosis and influencing factors of patients with different lymph node statuses after pathological complete response to neoadjuvant chemoradiotherapy in rectal cancer

Jianxi Zhou, Yunchuan Sun, Li Xiao, Hongling Lu, Xiaoming Yin, Yaru Kong, Yiyan Zhang, Wei Guo, Yingnan Zhou
Article Number: 359
Published online on: 22 May 2025

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Case Report

Malignant mesothelioma with a novel BAP1 germline frameshift mutation treated with dual immune checkpoint inhibitors: A case report

Na Zhou, Mingying Wu, Chenyu Wang, Mingming Yuan, Yuejuan Cheng, Huanwen Wu, Xin Gao, Shuangni Yu, Lin Zhao
Article Number: 358
Published online on: 21 May 2025

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Article Open Access

In vitro and in silico investigation of the critical role of GABAB receptor activation in human breast cancer and its natural agonists

Mustafa Hussein Ali, Ziyad Tariq Muhseen, Zahraa Yousif Al-Hajjaj, Hussein Hazim Al-Ghanimi, Abdulrahman Alshammari, Norah Abdullah Albekairi
Article Number: 357
Published online on: 21 May 2025

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Article Open Access

Integration of dual‑source dual‑energy CT quantitative parameters and ultrasound image features: A diagnostic method for extraglandular invasion of papillary thyroid carcinoma

Muhammad Asad Iqbal, Nida Fatima Moazzam, Hui Zhou, Jie Hou, Hui Sun, Donggang Pan, Xian Wang
Article Number: 356
Published online on: 21 May 2025

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Correction Open Access

[Corrigendum] Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation

Lina Qiao, Jianbao Zheng, Xianzhen Jin, Guangbing Wei, Guanghui Wang, Xuejun Sun, Xuqi Li
Article Number: 355
Published online on: 21 May 2025

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Review Open Access

Evolving role of deubiquitinating enzymes in oral cancer (Review)

Zidi Wang, Siyuan Cheng, Jianhui Wei, Jiandong Hu, Fenge Li, Wenhua Yang
Article Number: 354
Published online on: 19 May 2025

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Article Open Access

Role of the SPI1/CDKN2A/p53 signaling pathway in cuproptosis of lung adenocarcinoma cells

Jiayue An, Wei Song, Qin Wang, Boyu Tan, Xuan Fei, Ruoxi Wang, Siyan Li, Xiyu Lu, Youjie Li, Ning Xie
Article Number: 353
Published online on: 19 May 2025

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Case Report Open Access

Rechallenge of anti‑PD‑1 antibody combined with chemotherapy shows promising efficacy in the treatment of advanced metastatic hepatocellular carcinoma: A case report

Xiang Tan, Le Kang, Hao Chen, Xingyan Liu, Chi Du
Article Number: 352
Published online on: 19 May 2025

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Retraction Open Access

[Retracted] Genistein inhibits lung cancer cell stem‑like characteristics by modulating MnSOD and FoxM1 expression

Zhimin Fu, Xiaocheng Cao, Lihua Liu, Xiaozheng Cao, Yinghong Cui, Xiang Li, Meifang Quan, Kaiqun Ren, A Chen, Chang Xu, Yebei Qiu, Xiangding Chen, Zheng Wang, Jianguo Cao
Article Number: 351
Published online on: 19 May 2025

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Article Open Access

Comprehensive analysis of a palmitoylation‑related prognostic signature in colorectal cancer: Implications for immune therapy and personalized treatment

Xiaokang Wang, Jian Li, Zi Wang, Qingyun Wu
Article Number: 350
Published online on: 16 May 2025

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Case Report Open Access

Pancreatic metastasis from cervical cancer: A case report and literature review

Hailing Liao, Xiaoyan Chang, Xiaorong Hou, Fuquan Zhang
Article Number: 349
Published online on: 16 May 2025

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Article Open Access

Efficacy and safety of BCG and immune checkpoint inhibitors in non‑muscle invasive bladder cancer: A meta‑analysis with exploratory chemotherapy comparisons

Mohamed Mohamoud Adan, Xudong Mao, Lifeng Ding, Khalid Mohamoud Abdullahi, Gonghui Li
Article Number: 348
Published online on: 16 May 2025

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Case Report Open Access

Arterial perfusion chemoembolization combined with iodine‑125 seeds for stage IIB osteosarcoma: A case report

Linhao Ran, Fan Li, Li Jiang, Li Yang, Ying Liu
Article Number: 347
Published online on: 15 May 2025

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Article Open Access

Long‑term follow‑up outcomes of intraoperative radiotherapy for breast‑conserving treatment in early breast cancer: A retrospective cohort study

Xiaofan Xu, Lu Wang, Yuanyuan Cao, Jingyi Wang, Jie Yao, Liqun Huo, Yuqing Song, Wei Ding, Jun Gu, Qiurong Li
Article Number: 346
Published online on: 15 May 2025

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Article Open Access

Utility of the CPS + EG score with real‑life data in patients with breast cancer undergoing neoadjuvant chemotherapy

Ezgi Yildiz Yurekli, Seval Akay, Olcun Umit Unal
Article Number: 345
Published online on: 15 May 2025

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Case Report Open Access

Fan beam computed tomography‑guided online adaptive external radiotherapy for cervical cancer achieves pathological complete response: A case report

Haibo Peng, Ningyue Xu, Dong Gao, Huigang Tan, Tao Ren
Article Number: 344
Published online on: 14 May 2025

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Case Report Open Access

Spinal cord metastasis in a long‑term survivor of primary malignant glioblastoma: A case report 

Pengwei Hou, Meiyan Liu, Ziqi Li, Mingfa Cai, Chenzhu Cai
Article Number: 343
Published online on: 14 May 2025

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Review Open Access

Combination of radiotherapy and ICIs in advanced hepatocellular carcinoma: A systematic review of current evidence and future prospects (Review)

Cheng Ma, Xinlin Yu, Xialin Zhang, Lihong Su, Ou Jiang, Ran Cui
Article Number: 342
Published online on: 14 May 2025

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Article Open Access

Application and clinical translational value of a predictive model based on N7‑methylguanosine‑related long non‑coding RNAs in cervical squamous cell carcinoma

Jun Zhang, Yingna Bao, Zhilong Yu, Yu Lin
Article Number: 341
Published online on: 14 May 2025

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Case Report Open Access

Cerebral metastasis from anal squamous cell carcinoma: A case report and literature review

Elena Andreea Popa, Vanesa Marisa Tomatis, Esther Quick, Paul Stephen Mitchell, Chrisovalantis Tsimiklis, Annika Reann Mascarenhas
Article Number: 340
Published online on: 13 May 2025

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Article Open Access

AMIGO2 expression at the invasive front of bladder cancer predicts recurrence‑free and overall survival after radical cystectomy

Atsushi Yamamoto, Runa Izutsu, Heekyung Seong, Ryutaro Shimizu, Ryoma Nishikawa, Yusuke Kimura, Noriya Yamaguchi, Shuichi Morizane, Katsuya Hikita, Masashi Honda, Atsushi Takenaka, Futoshi Okada
Article Number: 339
Published online on: 13 May 2025

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Case Report Open Access

Primary pulmonary malignant melanoma with H3K27Me3 loss: A case report

Houqiang Li, Lanqing Zheng, Xunbin Yu, Linfeng Chen, Shanshan Lv, Xin Chen
Article Number: 338
Published online on: 13 May 2025

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Case Report Open Access

Successful robot‑assisted minimally invasive surgery for scirrhous gastric conduit cancer after esophagectomy: A case report

Koichi Okamoto, Yuta Sannomiya, Koki Furuse, Kaori Maruyama, Hisashi Nishiki, Akifumi Hashimoto, Daisuke Kaida, Takashi Miyata, Toshikatsu Tsuji, Hideto Fujita, Noriyuki Inaki, Shinichi Kinami, Itasu Ninomiya, Hiroyuki Takamura
Article Number: 337
Published online on: 12 May 2025

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Retraction Open Access

[Retracted] Metformin mitigates PLCε gene expression and modulates the Notch1/Hes and androgen receptor signaling pathways in castration‑resistant prostate cancer xenograft models

Qi Li, Ke Xu, Jianguo Tian, Zhicheng Lu, Jianming Pu
Article Number: 336
Published online on: 12 May 2025

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Article Open Access

Retroperitoneal growth of high‑grade serous ovarian carcinoma: A case report

Pengnan Hu, Weizhou Pan, Jun Yu, Hua Mi
Article Number: 335
Published online on: 09 May 2025

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Article Open Access

Establishment and evaluation of an automatic multi‑sequence MRI segmentation model of primary central nervous system lymphoma based on the nnU‑Net deep learning network method

Tao Wang, Xingru Tang, Jun Du, Yongqian Jia, Weiwei Mou, Guang Lu
Article Number: 334
Published online on: 09 May 2025

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Case Report

Total gastrectomy and extended D2 lymphadenectomy for primary gastric squamous cell carcinoma: A case report 

Binh Van Pham, Duy Duc Nguyen, Manh Dai Tran, Thanh Duy Nguyen, An Duc Thai, Binh Tien Nguyen, Ky Van Le, Hoa Thi Thanh Nguyen
Article Number: 333
Published online on: 08 May 2025

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Review

Comprehensive treatment of intermediate and advanced primary hepatocellular carcinoma based on transcatheter arterial chemoembolization (Review)

Xing Xu, Xue Zhang, Yang Zhao, Xiaoyang Zhang, Hongfang Tuo
Article Number: 332
Published online on: 07 May 2025

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Case Report Open Access

Breast cancer metastasis to the nasopharynx: A case report

Yandong Bian, Chen Song, Yuhui Nie, Xin Shen, Fu Hui, Guohua Yu
Article Number: 331
Published online on: 07 May 2025

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Article Open Access

Distinguishing acute leukemia subtypes: The role of hsa_circ_0012152 and hsa_circ_0020093 in peripheral blood

Qiming Ying, Dingfeng Lv, Ying Chen, Qitian Mu
Article Number: 330
Published online on: 07 May 2025

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Retraction Open Access

[Retracted] lncRNA‑CD160 decreases the immunity of CD8+ T cells through epigenetic mechanisms in hepatitis B virus infection

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 329
Published online on: 06 May 2025

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Article Open Access

Efficacy and safety of furmonertinib in patients with EGFR‑mutant advanced lung adenocarcinoma after failure of multiple lines of therapy: A single‑center retrospective study

Yumin Zheng, Xingyu Lu, Huijing Dong, Jia Li, Yulei Shen, Zhening Liu, Huijuan Cui
Article Number: 328
Published online on: 02 May 2025

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Article Open Access

Prophylactic cerebral irradiation sensitizes relapsed sensitive small cell lung cancer to temozolomide: A retrospective cohort study

Dan He, Shuxia Wei, Fenghao Geng, Lintao Li, Fengyu Li, Yanli Ge, Ruichang Lv, Weiwei Li, Zhijun Hao, Fengdi Jiang, Chao Meng, Shun Lu, Shuyu Zhang
Article Number: 327
Published online on: 02 May 2025

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Case Report Open Access

Sintilimab‑induced acute erosive hemorrhagic gastritis as an adverse reaction of third‑line therapy in a nasopharyngeal carcinoma patient: A case report

Wenqiang Tang, Yun Lv, Xiyue Yang, Kunyuan Gan, Gang Feng, Jie Li, Lu Ni, Yuxi Bai, Xiaobo Du, Feng Gao
Article Number: 326
Published online on: 02 May 2025

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Review Open Access

Application of multivalent aptamers in tumor diagnosis, analysis and therapy (Review)

Hongyue Zeng, Wenjing Zeng, Yaoyao Liang
Article Number: 325
Published online on: 02 May 2025

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Article

AKT1 and CTNNB1 mutations as drivers of paclitaxel resistance in breast cancer cells

Gulsum Altiparmak-Ulbegi, Gozde Hasbal-Celikok, Pinar Aksoy-Sagirli
Article Number: 324
Published online on: 02 May 2025

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Article Open Access

Prognostic value of the pretreatment Glasgow prognostic score or modified Glasgow prognostic score in patients with advanced cancer receiving immune checkpoint inhibitors: A systematic review and meta‑analysis

Lianghui Zhang, Lili Lin, Jie Ni, Tao Ling, Lingli Huang
Article Number: 323
Published online on: 02 May 2025

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Article Open Access

Establishment and validation of a clinical prediction model for colorectal adenoma risk factors

Dong-Lin Li, Ling-Ling Ma, Zhong-An Guan, Yu-Xin Zhao, Chuan Jiang
Article Number: 322
Published online on: 02 May 2025

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Case Report Open Access

Pulmonary pleomorphic carcinoma associated with cystic airspace and recurrent spontaneous pneumothorax: A case report

Qiangsheng Li, Jing Zhang, Youjie Gong, Xudong Wan, Song Zhang, Zhongwang Li, Jun Liu
Article Number: 321
Published online on: 02 May 2025

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Case Report Open Access

Composite B‑cell lymphoma and extranodal natural killer/T‑cell lymphoma presenting with distinct clone evolution and tumor microenvironment: A report of two cases

Qiuyue Wen, Qiuhui Li, Wei Yang, Xiaona Chang, Fang Zhu, Huaxiong Pan, Liling Zhang
Article Number: 320
Published online on: 02 May 2025

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Early postoperative complications and patient‑reported quality of life following breast‑conserving surgery with intraoperative radiotherapy: A prospective cohort study

Hongmei Han, Xuwen Liu, Baozhong Zhang, Jingjing Liu, Jing Wang, Qingsong Pang
Article Number: 268
Published online on: 27 April 2026

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Article Open Access

Exploring the mechanism of action of glaucocalyxin D against acute myeloid leukemia using network pharmacology, molecular docking and cellular experiments

Lian Chen, Weixian Yang, Weiqing Zhang, Heng Luo, Chen Yan
Article Number: 267
Published online on: 27 April 2026

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Review
Special Issue

Advances in cerebrospinal fluid biomarkers for the diagnosis, treatment and monitoring of leptomeningeal metastases (Review)

Huaixu Li, Wenwen Fan, Fengchun Mu, Cheng Fang, Ting Xiao, Jinghai Wan, Hongqing Cai
Article Number: 266
Published online on: 27 April 2026

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Article Open Access

Exploration of the effect and mechanism of Eclipta prostrata L. against gastric cancer based on network pharmacology and experimental verification

Weizhou Yu, Xiaohui Ni, Jing Wang, Wei Xia, Xinya Shen, Fan Qiu, Yuping Chen
Article Number: 265
Published online on: 27 April 2026

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Article Open Access

Neoadjuvant radiotherapy for resectable hepatocellular carcinoma with vascular invasion: A systematic review and meta‑analysis

Yuhao Su, Yuxin Liang, Deyuan Zhong, Hongtao Yan, Qinyan Yang, Xiaolun Huang
Article Number: 264
Published online on: 27 April 2026

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Article Open Access

Computational discovery of novel colony‑stimulating factor‑1 receptor as a potential therapeutic biomarker in osteosarcoma and a novel inhibitor from herbal sources

Hui Zhang, Shiwei Wu, Dan Luo, Jincai Guo
Article Number: 263
Published online on: 24 April 2026

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Article Open Access

Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta‑analysis

Javier Angel Canelas Fernández, Jéssica Alonso‑Molero, Paz Rodríguez‑Cundín, Javier Llorca, Inés Gómez‑Acebo, Trinidad Dierssen‑Sotos
Article Number: 262
Published online on: 24 April 2026

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Article Open Access

Evaluation of smoking status as a prognostic factor under immune checkpoint inhibitor treatment: A single center analysis

Christoph Schaefers, Annika Poch, Anika Forstreuter, Frederike Bokemeyer, Carsten Bokemeyer, Christoph Seidel
Article Number: 261
Published online on: 24 April 2026

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Correction Open Access

[Corrigendum] CDDO, a PPAR‑γ ligand, inhibits TPA‑induced cell migration and invasion through a PPAR‑γ‑independent mechanism

Hye-Yeon Jang, On-Yu Hong, Hyun Jo Youn, Jaeuk Jung, Eun Yong Chung, Sung Hoo Jung, Jong-Suk Kim
Article Number: 260
Published online on: 24 April 2026

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Review Open Access

Dual roles of neutrophil extracellular traps in tumors: From pro‑metastatic mechanisms to immunotherapeutic strategies (Review)

Mingxin Guo, Han Wang, Jiaqi Zeng, Ning Wu, Zhiqiang Hu, Ao Xue, Ting Dai
Article Number: 259
Published online on: 23 April 2026

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Review Open Access

Emerging role of protein arginine methyltransferase 5 in gastrointestinal cancer (Review)

Rui Zhang, Yiwen Lu, Xiaohua Fang, Fengquan Zhang, Weidong Wu, Jie Song, Zhenzhen Liang
Article Number: 258
Published online on: 23 April 2026

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Case Report Open Access

Adjuvant immunotherapy plus chemotherapy and maintenance immunotherapy for pulmonary lymphoepithelioma‑like carcinoma with hepatitis B virus infection, KRAS mutation and high expression of programmed death ligand 1: A case report

Jing Zhu, Qing-Gui Xu, Jiao Zhu, Rui-Xiang Zhou, Yu-Chuan Zhou, Zhi-Ke Li
Article Number: 257
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Interleukin‑17 promotes the development of cisplatin resistance in colorectal cancer

Guolong Sui, Yingna Qiu, Haijuan Yu, Qingbin Kong, Baowen Zhen
Article Number: 256
Published online on: 22 April 2026

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Article Open Access

An m6A‑programmed cell death signature predicts prognosis and identifies STK25 as a therapeutic target in colon adenocarcinoma

Hezhi Yu, Tihui Li, Xiaoyun Huang, Zihan Chen, Zixiang Lin, Fenglin Chen
Article Number: 255
Published online on: 22 April 2026

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Article Open Access

METTL5 reprograms glycolytic metabolism and promotes non‑small cell lung cancer progression by modifying PGAM1

Yuchen Shan, Xiaoyu Duan, Kai Yuan, Ming Lou, Qiyong Wu, Zhaojia Gao
Article Number: 254
Published online on: 20 April 2026

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Article Open Access

Clinical features and outcomes of peripheral T‑cell lymphoma, not otherwise specified: A single institution retrospective analysis of 30 cases

Meng-Xue Ma, Ya-Li Zhang, Li-Na Xing, Qiu-Yi Wang, Shukai Qiao
Article Number: 253
Published online on: 20 April 2026

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Article Open Access

BUD23 is associated with malignancy and correlates with immune infiltration in NSCLC

Yonghuang Tan, Jun Ma, Jiangli Zhou, Jianjun Lu
Article Number: 252
Published online on: 20 April 2026

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Article Open Access

Evaluation of NID2 and CDO1 methylation for ovarian cancer screening

Shuilian Wu, Jing Jin, Yuanyuan Cao, Xiaofan He, Qiang Hou, Mingfeng Jiang
Article Number: 251
Published online on: 20 April 2026

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Retraction Open Access

[Retracted] Improved ataxia telangiectasia mutated kinase inhibitor KU60019 provides a promising treatment strategy for non‑invasive breast cancer

Ying Zhu, Changfei Mao, Jianzhong Wu, Shuchun Li, Rong Ma, Haixia Cao, Minghua Ji, Changwen Jing, Jinhai Tang
Article Number: 250
Published online on: 20 April 2026

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Case Report Open Access

Fever and leukemoid reaction in bladder cancer: A case report

Tianrun Huang, Jiguo Xu, Yuwei He, Yu Shen, Chenlong Chu, Jingyuan Lu, Parehe Alimu, Chunlei Chen, Jianhe Liu
Article Number: 249
Published online on: 20 April 2026

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Article Open Access

Prognostic effect and prognostic factors of TACE for the treatment of unresectable hepatocellular carcinoma: Propensity score matching analysis

Liangliang Zhang, Cancan Li, Hui Guo, Xue Zhang, Wei Liu, Xing Xu
Article Number: 248
Published online on: 16 April 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA BX357664 inhibits cell proliferation and metastasis in human lung cancer

Shu-Hui Xiao, Gong-Xiang Li, Lingli Quan
Article Number: 247
Published online on: 16 April 2026

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Article

Safety and feasibility of total neoadjuvant FLOT chemotherapy in locally‑advanced gastric and gastroesophageal junction cancer

Oleksii Dobrzhanskyi, Andrii Horodetskyi, Mykyta Pepenin, Yurii Kondratskyi
Article Number: 246
Published online on: 16 April 2026

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Article Open Access

Vasculogenic mimicry and breast cancer prognosis: Insights into predictive model development

Zhifeng Wu, Yueyue Teng, Shengchao Huang, Shiming Shi, Pu Qiu, Leyao Shan, Meihua Lin, Yuanqi Zhang
Article Number: 245
Published online on: 15 April 2026

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Article Open Access

Effect and safety analysis of raltitrexed peritoneal perfusion in patients with intermediate and advanced colorectal cancer

Yanhua Wan, Xiaoyun Dai, Liang Chao
Article Number: 244
Published online on: 15 April 2026

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Article Open Access

Mechanism of action of alkaloids in Fritillaria‑induced autophagy and apoptosis in non‑small cell lung cancer

Mengru Teng, Mengrui Zhang, Jun He, Wai Ming Tse, Kathy Wai Gaun Tse, Chengwu Liu, Bengui Ye
Article Number: 243
Published online on: 15 April 2026

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Article Open Access

Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

You Meng, Ze-Xin Han, Jie Zhu, Ying Wang, Yue-Qing Huang, Zhong-Hua Zou, Yu-Yuan Ma, Yi-Fan Li, Han Wang, Ying Li, Lian Lian, Wen-Jie Wang
Article Number: 242
Published online on: 15 April 2026

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Correction Open Access

[Corrigendum] Silencing glioma‑associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro

Zeming Hu, Fangfang Xie, Ang Hu, Mengjing Xu, Yuwen Liu, Jiankang Zhang, Jianbo Xiao, Yunlei Song, Jianing Zhong, Bin Chen
Article Number: 241
Published online on: 15 April 2026

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Article

A novel inflammation and tumor marker‑based prognostic score, neutrophil‑lymphocyte ratio‑C‑reactive protein‑Ca19‑9, in metastatic gastric cancer

Berkan Karabuğa, Osman Bilge Kaya, Ekin Konca Karabuğa, Ergin Aydemir, Mehmet Emin Yilmaz, Sedef Tatar Bolat, Ayşegül Uçkun, Enes Kaptan, Öztürk Ateş, Mustafa Büyükkör
Article Number: 240
Published online on: 15 April 2026

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Article Open Access

KRAS (G12D)‑selective inhibitor MRTX1133 suppresses proliferation and differentially modulates chemosensitivity in ovarian mucinous carcinoma

Ryota Watano, Hiroaki Mizukami, Yasushi Saga
Article Number: 239
Published online on: 15 April 2026

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Article

Intensity‑ and time‑dependent anticancer effects of alternating electric fields in non‑small cell lung cancer cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 238
Published online on: 15 April 2026

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Review Open Access

KLF family of proteins in gastrointestinal tumors (Review)

Jingjing Zhang, Rupu Zhao, Pengjie Yang, Yong Zhu, Benben Zhu
Article Number: 237
Published online on: 15 April 2026

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Article

Establishment and validation of a diagnostic model for evaluating synchronous liver metastasis in pancreatic cancer using comprehensive blood biochemical indicators

Yiyi Jiang, Gaoyao Peng, Songqing He, Jiangfa Li
Article Number: 236
Published online on: 14 April 2026

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Review Open Access

Soluble isoforms of EGFR family in breast cancer: Advances and clinical relevance (Review)

Peng Yang, Xinnong Jiang, Fangguo He
Article Number: 235
Published online on: 14 April 2026

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Article Open Access

Thrombospondin‑1 triggers calreticulin expression in human mucoepidermoid carcinoma MC‑3 cells via the PERK/CHOP pathway

Shengwei Bao, Yuanyuan Zhu, Lijuan Guo, Sen Yang
Article Number: 234
Published online on: 14 April 2026

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Article Open Access

Unveiling the prognostic and immunotherapeutic role of Tregs in lung cancer using integrated analysis of single‑cell and bulk RNA‑sequencing

Hongwei He, Zhiming Xiao, Jijun Xue, Yu Zhang, Jichen Qu, Peng Wu, Qiangjun He
Article Number: 233
Published online on: 14 April 2026

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Review Open Access

Nobiletin in cancer therapy: Emerging insights into multi-target mechanisms, overcoming drug resistance and therapeutic translation (Review)

Yanfang Zhang, Qingcai Li, Wenbin Yu, Bin He, Jiahua Peng, Bin Yao
Article Number: 232
Published online on: 14 April 2026

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Expression of Concern Open Access

[Expression of Concern] Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF‑κB pathway

Wen-Yue Liu, Xu Wu, Cheng-Quan Liao, Jie Shen, Jun Li
Article Number: 231
Published online on: 14 April 2026

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Article

Pretreatment C‑reactive protein‑triglyceride‑glucose index predicts survival in patients with FLOT‑treated locally advanced gastric and gastroesophageal junction cancer

Ayşegül Dumludağ, Mehmet Torun, Osman Sütçüoğlu
Article Number: 230
Published online on: 09 April 2026

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Case Report

Intravascular large B‑cell lymphoma mimicking an orbital mass lesion and bilateral cavernous sinus syndrome: A case report

Qiong Wu, Yiran Jia, Bentao Yang, Xiaojin He, Hongjuan Liu, Libin Jiang
Article Number: 229
Published online on: 09 April 2026

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Correction Open Access

[Corrigendum] FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo

Kun Zhao, Jie Gao, Jihua Shi, Chengcheng Shi, Chun Pang, Jie Li, Wenzhi Guo, Shuijun Zhang
Article Number: 228
Published online on: 09 April 2026

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Article Open Access

Role of CDX2 in the prognosis of colorectal cancer across stages 0‑IV

Guojun Tong, Hai Qian, Yuefeng Fei, Sheng Yu, Kun Guo, Wenwen Yu, Jing Li, Sicheng Yan
Article Number: 227
Published online on: 08 April 2026

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Article Open Access

Exploring multiple biomarkers and constructing ferroptosis‑associated competing endogenous RNA networks as dual targets in retinoblastoma

Zhengjia Kang, Gaoqin Liu
Article Number: 226
Published online on: 08 April 2026

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Review Open Access

Role of mesenchymal stem cells and their derived exosomes in cervical cancer: Bidirectional mechanisms and research progress (Review)

Xue Li, Daqing Wang
Article Number: 225
Published online on: 08 April 2026

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Review Open Access

Hypoxia‑inducible factors: Regulatory functions and status as a therapeutic target in gastric cancer (Review)

Jia Xu, Guangzhi Ding, Yiming Wang, Chang Liu
Article Number: 224
Published online on: 08 April 2026

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Article Open Access

Machine learning‑based programmed cell death gene signature for prognosis and drug sensitivity in breast cancer

Nan Wu, Zhongting Fan
Article Number: 223
Published online on: 08 April 2026

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Article Open Access

Assessing the density of lymph node metastasis in various inguinal regions of penile cancer using the nine‑section method: A prospective study

Chen Hu, Longguo Dai, Hongyi Wu, Yu Bai, Jun Li, Haiyang Jiang, Haoli Yin, Ying Bi, Wenzhao Wu, Ruiqian Li, Hong Shi
Article Number: 222
Published online on: 08 April 2026

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Article Open Access

Overexpression and knockdown of 5‑lipoxygenase regulates the migration and invasion of colorectal cancer cells

Xuyang Li, Jiletu Huge, Xiaoling Wang, Jing Zhou, Xiudan Li, Xiaoyan Gao, Tiewei Shi, Chunying Bai
Article Number: 221
Published online on: 08 April 2026

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Case Report

Targeting TROP‑2 in treatment‑resistant non‑small cell lung cancer harboring the KRAS G12C mutation and TROP‑2 upregulation: A case report

Lu Sun, Ying Xiong, Xiaobing Li, Yi Peng
Article Number: 220
Published online on: 08 April 2026

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Article Open Access

Exosomal‑miR‑32‑5p directly targets FOXN2 to regulate the proliferation, migration and apoptosis of uterine corpus endometrial carcinoma via the PI3K/AKT/BCL‑2 pathway

Xin Chen, Huihui Li, Xiang Cheng, Yirong Cai, Guangyi Guo
Article Number: 219
Published online on: 08 April 2026

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Expression of Concern Open Access

[Expression of Concern] PRKACB is downregulated in non‑small cell lung cancer and exogenous PRKACB inhibits proliferation and invasion of LTEP‑A2 cells

Yong Chen, Ying Gao, Ye Tian, Da-Li Tian
Article Number: 218
Published online on: 07 April 2026

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Review Open Access

Lactylation enzymes in cancer: Mechanisms and novel therapeutic approaches (Review)

Guiyang Tang, Hanrong Zuo, Rou Long, Chaohui Zhang, Yufan Lv, Xinyu Luo, Jieya Qiu, Jianhong Zuo
Article Number: 217
Published online on: 02 April 2026

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Case Report Open Access

Comprehensive treatment for intracranial invasive sinonasal intestinal‑type adenocarcinoma with a focus on radiotherapy dosage and immunological combination therapy: A case report

Lianlian Yang, Qian Zhao, Fang Yi, Wenyan Guo, Qiongwen Zhang, Song Zhou, Dong Li, Zhihui Li
Article Number: 216
Published online on: 02 April 2026

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Review Open Access

Biological basis and clinical translation prospects of circulating cell‑free DNA in precision management of breast cancer (Review)

Li-Zhuang Fan, Ai-Lan Xu, Ya-Ru Xu, Luo Yang, Fang Yuan, Xin Nie
Article Number: 215
Published online on: 02 April 2026

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Review Open Access

Cutting‑edge advances in endocrine therapy for breast cancer (Review)

Yumei Dong, Lihua Shao, Qiong Li, Yuexiao Qi, Tingting Liu, Shihong Wei, Haiyan Qi
Article Number: 214
Published online on: 02 April 2026

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Case Report Open Access

Rapidly progressive squamous lung cancer with peripheral blood eosinophilia in a 25-year-old woman: A case report

Mingrui Zhang, Huanfang Fan, Chunxia Sun, Dehui Li, Jiangya Gan, Yun He, Jiaqi Chen
Article Number: 213
Published online on: 02 April 2026

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Article Open Access

Dynamic curve type serves as an effective tool for the diagnosis of benign or malignant non‑mass enhancements on breast MRI

Tara Farooq Kareem, Areege Mustafa Kamal, Munawar Al Nakash
Article Number: 212
Published online on: 02 April 2026

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Article Open Access

Clinical predictors of leptomeningeal metastasis from lung adenocarcinoma based on retrospective analysis

Yunyun Lu, Yi Lu, Yueyue Zhang, Hongyuan Du, Xuan Cao, Dexi Jin, Guofu Chen, Xiaohui Yang
Article Number: 211
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Delphinidin induces cell cycle arrest and apoptosis in HER‑2 positive breast cancer cell lines by regulating the NF‑κB and MAPK signaling pathways

Ailin Wu, Yanfeng Zhu, Bin Han, Jiayuan Peng, Xiaomin Deng, Wei Chen, Jingchang Du, Yu Ou, Xiaoli Peng, Xiaoping Yu
Article Number: 210
Published online on: 01 April 2026

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Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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July-2026 Volume 32 Issue 1

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Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Expression of Concern Open Access

[Expression of Concern] Rap2B promotes the proliferation and migration of human glioma cells via activation of the ERK pathway

Guohong Shi, Zhen Zhang
Article Number: 290
Published online on: 11 May 2026

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Article Open Access

A novel prognostic biomarker combining TP53 loss‑of‑function and amplification of different combinations of nine genes in lung squamous cell carcinoma treated with chemotherapy

Yuli Li, Ting Hou, Hongjie Liu, Haiwei Du, Li Qiu, Yajing Zhang, Guiping Zhang, Yuan Tang
Article Number: 289
Published online on: 11 May 2026

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Article Open Access

Meta‑analysis of efficacy comparisons between standard‑ and low‑dose Bacillus Calmette‑Guerin vaccines in managing non‑muscular invasive bladder cancer

Xiaoxi Liu, Yige Bao
Article Number: 288
Published online on: 08 May 2026

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Correction Open Access

[Corrigendum] EGFR and ERK activation resists flavonoid quercetin‑induced anticancer activities in human cervical cancer cells in vitro

Xin Chen, Pengli Xu, Huijun Zhang, Xiaosan Su, Lihua Guo, Xuhong Zhou, Junliang Wang, Peng Huang, Qingzhi Zhang, Ruifen Sun
Article Number: 287
Published online on: 08 May 2026

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Article Open Access

Cumulative evidence for associations between matrix metalloproteinase‑1, ‑3 and ‑8 variants and cancer risk

Suqin Xu, Xianping Liu, Chenglu Huang
Article Number: 286
Published online on: 07 May 2026

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Article

PD‑1 inhibitors combined with tyrosine kinase inhibitor‑associated hypothyroidism is a predictive factor for antitumor effectiveness in male patients with hepatocellular carcinoma

Bailu Cao, Min Ai, Ping Huang, Huan Zhong
Article Number: 285
Published online on: 07 May 2026

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Correction Open Access

[Corrigendum] Proliferation, migration and invasion of triple negative breast cancer cells are suppressed by berbamine via the PI3K/Akt/MDM2/p53 and PI3K/Akt/mTOR signaling pathways

Lili Liu, Jiadong Yan, Ying Cao, Yan Yan, Xiang Shen, Binbin Yu, Li Tao, Shusheng Wang
Article Number: 284
Published online on: 06 May 2026

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Article Open Access

Evaluation of ct‑DNA and mutational status in liquid biopsy of patients with metastatic colorectal cancer

George Zarkavelis, Melina Yerolatsite, Panagiotis Ntellas, Aikaterini Tsantikidi, Irene Papadopoulou, Nanteznta Torounidou, Katerina Dadouli, George Nasioulas, Eleftherios Kampletsas, George Pentheroudakis
Article Number: 283
Published online on: 06 May 2026

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Article Open Access

Immunotherapy retreatment with serplulimab vs. chemotherapy in extensive‑stage advanced small cell lung cancer

Xinhang Gu, Xue Wu, Jiaxiao Geng, Yan Wang, Chengxin Liu
Article Number: 282
Published online on: 06 May 2026

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Article Open Access

Next‑generation sequencing elucidates the distinct mutational landscape of SMARCA4‑deficient lung cancer

Feicheng Yang, Yuzhong Yang, Zhihong Chen, Yanchun Li, Yinghui Song
Article Number: 281
Published online on: 05 May 2026

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Correction Open Access

[Corrigendum] Eupafolin inhibits breast cancer cell proliferation and induces apoptosis by inhibiting the PI3K/Akt/mTOR pathway

Jiahui Wei, Xuefeng Zhang, Huihao Pan, Song He, Bao Yuan, Qing Liu, Jiabao Zhang, Yu Ding
Article Number: 280
Published online on: 05 May 2026

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Article

Mutational landscape in the precancerous stages of sporadic colorectal cancer

Anna Valickova, Marketa Urbanova, Josef Horak, Jiri Jungwirth, Jan Kral, Tomas Hucl, Veronika Makajevova, Sandra Summerova, Pavel Kohout, Radoslav Matej, Pavel Vodicka, Veronika Vymetalkova
Article Number: 279
Published online on: 04 May 2026

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Article Open Access

Comparing the efficacy of immune checkpoint inhibitors with and without microwave ablation in advanced hepatocellular carcinoma in real‑world clinical practice: A retrospective cohort study

Chun Wei, Sizhong Chen, Li Ding, Ting Zhou, Fan Huang, Yong Wang, Ou Jiang, Yu Liu
Article Number: 278
Published online on: 04 May 2026

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Expression of Concern Open Access

[Expression of Concern] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 277
Published online on: 29 April 2026

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Review Open Access

Watch‑and‑wait in rectal cancer: A critical appraisal of promise, perils and unresolved contours of organ preservation (Review)

Xinqiang Zhu, Beibei Ge, Linchun Wen, Siwei Shan
Article Number: 276
Published online on: 28 April 2026

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Review Open Access

Multi‑omics profiling of pancreatic neuroendocrine tumors: Interplay of genomic instability and the tumor microenvironment (Review)

Yin Wan, Yingnan Zhang, Philip A. Philip, Herbert Chen, Bassel El‑Rayes, Asfar S. Azmi, Yang Shi
Article Number: 275
Published online on: 28 April 2026

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Article Open Access

SOX2‑positive upper tract urothelial carcinoma: Clinicopathological characteristics and therapeutic implications

Hitomi Yasukawa, Yoshinori Ikehata, Naotaka Nishiyama, Hiroshi Kitamura
Article Number: 274
Published online on: 28 April 2026

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Article Open Access

Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report

Yuping Zeng, Song Mu, Guosheng Li, Zhengzi Liang, Qinghua Ji, Yunhuan Zhen, Wenling Wang, Weiwei Chen
Article Number: 273
Published online on: 28 April 2026

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Article Open Access

LINC00184 promotes esophageal squamous cell carcinoma progression via DNMT1‑mediated methylation of the NDRG2 promoter and PI3K/AKT pathway activation

Junjun Guo, Shenbo Fu, Jia Liu, Lina Li, Jin Zhao, Fenggang Wang, Wenan Wu, Xu Chen, Enxiao Li
Article Number: 272
Published online on: 28 April 2026

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Article Open Access

A clear cell sarcoma tumor of the finger with an unusual presentation misdiagnosed as a glomus tumor in an adolescent patient: A case report

Abdulrahman Alaseem, Hatim Khoja, Khalid Murrad, Sarah Alkhalife, Nouf Altwaijri, Abdullah Almawi, Abdulaziz Bin Dakhil, Abdulaziz Alhammad, Banan Alqady, Eman Najjar
Article Number: 271
Published online on: 28 April 2026

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Case Report Open Access

Primary thyroid lymphoma with Hashimoto's thyroiditis: A case report and literature review

Fangshu Liu, Xueya Xin, Kai Tan, Xinv Chen, Chanjuan Shen, Qiuhong Yang
Article Number: 270
Published online on: 28 April 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo inhibition of tumor cell viability by combined dihydroartemisinin and doxorubicin treatment, and the underlying mechanism

Xiang Tai, Xiao-Bei Cai, Zhang Zhang, Rui Wei
Article Number: 269
Published online on: 28 April 2026

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