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Case Report Open Access

Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report

  • Authors:
    • Yun He
    • Huanfang Fan
    • Zhihua Du
    • Dehui Li
    • Yiting Gu
    • Zihui Liu
  • View Affiliations / Copyright

    Affiliations: The Graduate School, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050011, P.R. China, Second Department of Oncology, The First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050011, P.R. China
    Copyright: © He et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 369
    |
    Published online on: May 27, 2025
       https://doi.org/10.3892/ol.2025.15115
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Abstract

The present study reports on the case of a middle‑aged female patient who presented with a rapidly progressing pigmented skin lesion on the periphery, combined with multiple intracranial, pulmonary, hepatic and skeletal malignancies. The case was not clear in terms of histopathological manifestations and other aspects, which made the diagnosis of melanoma difficult. The present case details the challenges in the diagnostic process, as well as the importance of multidisciplinary comprehensive diagnosis and treatment, aiming to provide a reference for clinicians when dealing with similar complex pigmented skin lesions.
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Copy and paste a formatted citation
Spandidos Publications style
He Y, Fan H, Du Z, Li D, Gu Y and Liu Z: Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report. Oncol Lett 30: 369, 2025.
APA
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., & Liu, Z. (2025). Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report. Oncology Letters, 30, 369. https://doi.org/10.3892/ol.2025.15115
MLA
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., Liu, Z."Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report". Oncology Letters 30.1 (2025): 369.
Chicago
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., Liu, Z."Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report". Oncology Letters 30, no. 1 (2025): 369. https://doi.org/10.3892/ol.2025.15115
Copy and paste a formatted citation
x
Spandidos Publications style
He Y, Fan H, Du Z, Li D, Gu Y and Liu Z: Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report. Oncol Lett 30: 369, 2025.
APA
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., & Liu, Z. (2025). Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report. Oncology Letters, 30, 369. https://doi.org/10.3892/ol.2025.15115
MLA
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., Liu, Z."Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report". Oncology Letters 30.1 (2025): 369.
Chicago
He, Y., Fan, H., Du, Z., Li, D., Gu, Y., Liu, Z."Pigmented skin lesions with atypical histopathology indicating a diagnosis of multiple metastases of melanoma: A case report". Oncology Letters 30, no. 1 (2025): 369. https://doi.org/10.3892/ol.2025.15115
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