|
1
|
Siegel RL, Miller KD, Wagle NS and Jemal
A: Cancer statistics, 2023. CA Cancer J Clin. 73:17–48.
2023.PubMed/NCBI
|
|
2
|
Cao M, Li H, Sun D and Chen W: Cancer
burden of major cancers in China: A need for sustainable actions.
Cancer Commun (Lond). 40:205–210. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Chaffer CL and Weinberg RA: A perspective
on cancer cell metastasis. Science. 331:1559–1564. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Clark AG and Vignjevic DM: Modes of cancer
cell invasion and the role of the microenvironment. Curr Opin Cell
Biol. 36:13–22. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Xu D, Shao F, Bian X, Meng Y, Liang T and
Lu Z: The evolving landscape of noncanonical functions of metabolic
enzymes in cancer and other pathologies. Cell Metab. 33:33–50.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Pan C, Li B and Simon MC: Moonlighting
functions of metabolic enzymes and metabolites in cancer. Mol Cell.
81:3760–3774. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Lv L and Lei Q: Proteins moonlighting in
tumor metabolism and epigenetics. Front Med. 15:383–403. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Martínez-Reyes I and Chandel NS: Cancer
metabolism: Looking forward. Nat Rev Cancer. 21:669–680. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Lin YH, Wu MH, Huang YH, Yeh CT, Cheng ML,
Chi HC, Tsai CY, Chung IH, Chen CY and Lin KH: Taurine up-regulated
gene 1 functions as a master regulator to coordinate glycolysis and
metastasis in hepatocellular carcinoma. Hepatology. 67:188–203.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Warburg O: On the origin of cancer cells.
Science. 123:309–314. 1956. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
He J, Li F, Zhou Y, Hou X, Liu S, Li X,
Zhang Y, Jing X and Yang L: LncRNA XLOC_006390 promotes pancreatic
carcinogenesis and glutamate metabolism by stabilizing c-Myc.
Cancer Lett. 469:419–428. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Robey RB and Hay N: Is Akt the ‘Warburg
kinase’?-Akt-energy metabolism interactions and oncogenesis. Semin
Cancer Biol. 19:25–31. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Xu F, Yan JJ, Gan Y, Chang Y, Wang HL, He
XX and Zhao Q: miR-885-5p negatively regulates warburg effect by
silencing hexokinase 2 in liver cancer. Mol Ther Nucleic Acids.
18:308–319. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yin D, Hua L, Wang J, Liu Y and Li X: Long
Non-Coding RNA DUXAP8 facilitates cell viability, migration, and
glycolysis in non-small-cell lung cancer via regulating HK2 and
LDHA by Inhibition of miR-409-3p. Onco Targets Ther. 13:7111–7123.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Guo T, Peng S, Liu D and Li Y: Long
Non-coding RNA LOXL1-AS1 facilitates colorectal cancer progression
via regulating miR-1224-5p/miR-761/HK2 axis. Biochem Genet.
60:2416–2433. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yu T, Li G, Wang C, Gong G, Wang L, Li C,
Chen Y and Wang X: MIR210HG regulates glycolysis, cell
proliferation, and metastasis of pancreatic cancer cells through
miR-125b-5p/HK2/PKM2 axis. RNA Biol. 18:2513–2530. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Chen X, She P, Wang C, Shi L, Zhang T,
Wang Y, Li H, Qian L and Li M: Hsa_circ_0001806 promotes glycolysis
and cell progression in hepatocellular carcinoma through
miR-125b/HK2. J Clin Lab Anal. 35:e239912021. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ding Z, Guo L, Deng Z and Li P: Circ-PRMT5
enhances the proliferation, migration and glycolysis of hepatoma
cells by targeting miR-188-5p/HK2 axis. Ann Hepatol. 19:269–279.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Hong F, Deng Z, Tie R and Yang S:
Hsa_circ_0045932 regulates the progression of colorectal cancer by
regulating HK2 through sponging miR-873-5p. J Clin Lab Anal.
36:e246412022. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zheng X, Shao J, Qian J and Liu S:
circRPS19 affects HK2-mediated aerobic glycolysis and cell
viability via the miR-125a-5p/USP7 pathway in gastric cancer. Int J
Oncol. 63:982023. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Li S, Zhu K, Liu L, Gu J, Niu H and Guo J:
lncARSR sponges miR-34a-5p to promote colorectal cancer invasion
and metastasis via hexokinase-1-mediated glycolysis. Cancer Sci.
111:3938–3952. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yang W, Xia Y, Hawke D, Li X, Liang J,
Xing D, Aldape K, Hunter T, Alfred Yung WK and Lu Z: PKM2
phosphorylates histone H3 and promotes gene transcription and
tumorigenesis. Cell. 150:685–696. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Alquraishi M, Puckett DL, Alani DS,
Humidat AS, Frankel VD, Donohoe DR, Whelan J and Bettaieb A:
Pyruvate kinase M2: A simple molecule with complex functions. Free
Radic Biol Med. 143:176–192. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Wang L, Wang H, Wu B, Zhang C, Yu H, Li X,
Wang Q, Shi X, Fan C, Wang D, et al: Long Noncoding RNA LINC00551
suppresses glycolysis and tumor progression by regulating
c-Myc-mediated PKM2 expression in lung adenocarcinoma. Onco Targets
Ther. 13:11459–11470. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Liang Y, Zhang D, Zheng T, Yang G, Wang J,
Meng F, Liu Y, Zhang G, Zhang L, Han J, et al: lncRNA-SOX2OT
promotes hepatocellular carcinoma invasion and metastasis through
miR-122-5p-mediated activation of PKM2. Oncogenesis. 9:542020.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ren J, Li W, Pan G, Huang F, Yang J, Zhang
H, Zhou R and Xu N: miR-142-3p modulates cell invasion and
migration via PKM2-mediated aerobic glycolysis in colorectal
cancer. Anal Cell Pathol (Amst). 2021:99277202021.PubMed/NCBI
|
|
27
|
Bian Z, Zhang J, Li M, Feng Y, Wang X,
Zhang J, Yao S, Jin G, Du J, Han W, et al: LncRNA-FEZF1-AS1
promotes tumor proliferation and metastasis in colorectal cancer by
regulating PKM2 signaling. Clin Cancer Res. 24:4808–4819. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Li Q, Pan X, Zhu D, Deng Z, Jiang R and
Wang X: Circular RNA MAT2B promotes glycolysis and malignancy of
hepatocellular carcinoma through the miR-338-3p/PKM2 axis under
hypoxic stress. Hepatology. 70:1298–1316. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gao Y, Yang F, Yang XA, Zhang L, Yu H,
Cheng X, Xu S, Pan J, Wang K and Li P: Mitochondrial metabolism is
inhibited by the HIF1α-MYC-PGC-1β axis in BRAF V600E thyroid
cancer. FEBS J. 286:1420–1436. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Zhou M, He J, Li Y, Jiang L, Ran J, Wang
C, Ju C, Du D, Xu X, Wang X, et al: N6-methyladenosine
modification of REG1α facilitates colorectal cancer progression via
β-catenin/MYC/LDHA axis mediated glycolytic reprogramming. Cell
Death Dis. 14:5572023. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Chen M, Cen K, Song Y, Zhang X, Liou YC,
Liu P, Huang J, Ruan J, He J, Ye W, et al:
NUSAP1-LDHA-Glycolysis-Lactate feedforward loop promotes Warburg
effect and metastasis in pancreatic ductal adenocarcinoma. Cancer
Lett. 567:2162852023. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kotowski K, Rosik J, Machaj F, Supplitt S,
Wiczew D, Jabłońska K, Wiechec E, Ghavami S and Dzięgiel P: Role of
PFKFB3 and PFKFB4 in cancer: Genetic basis, impact on disease
development/progression, and potential as therapeutic targets.
Cancers (Basel). 13:9092021. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lai S, Quan Z, Hao Y, Liu J, Wang Z, Dai
L, Dai H, He S and Tang B: Long Non-coding RNA LINC01572 promotes
hepatocellular carcinoma progression via sponging miR-195-5p to
enhance PFKFB4-mediated glycolysis and PI3K/AKT activation. Front
Cell Dev Biol. 9:7830882021. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Holman GD: Chemical biology probes of
mammalian GLUT structure and function. Biochem J. 475:3511–3534.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Wood IS and Trayhurn P: Glucose
transporters (GLUT and SGLT): Expanded families of sugar transport
proteins. Br J Nutr. 89:3–9. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Yu M, Yongzhi H, Chen S, Luo X, Lin Y,
Zhou Y, Jin H, Hou B, Deng Y, Tu L and Jian Z: The prognostic value
of GLUT1 in cancers: A systematic review and meta-analysis.
Oncotarget. 8:43356–43367. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Macheda ML, Rogers S and Best JD:
Molecular and cellular regulation of glucose transporter (GLUT)
proteins in cancer. J Cell Physiol. 202:654–662. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Shang R, Wang M, Dai B, Du J, Wang J, Liu
Z, Qu S, Yang X, Liu J, Xia C, et al: Long noncoding RNA SLC2A1-AS1
regulates aerobic glycolysis and progression in hepatocellular
carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway. Mol Oncol.
14:1381–1396. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Liu H, Zhang Q, Song Y, Hao Y, Cui Y,
Zhang X, Zhang X, Qin Y, Zhu G, Wang F, et al: Long non-coding RNA
SLC2A1-AS1 induced by GLI3 promotes aerobic glycolysis and
progression in esophageal squamous cell carcinoma by sponging
miR-378a-3p to enhance Glut1 expression. J Exp Clin Cancer Res.
40:2872021. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Cai K, Chen S, Zhu C, Li L, Yu C, He Z and
Sun C: FOXD1 facilitates pancreatic cancer cell proliferation,
invasion, and metastasis by regulating GLUT1-mediated aerobic
glycolysis. Cell Death Dis. 13:7652022. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Song MY, Lee DY, Yun SM and Kim EH: GLUT3
promotes epithelial-mesenchymal transition via TGF-β/JNK/ATF2
signaling pathway in colorectal cancer cells. Biomedicines.
10:18372022. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Shi Y, Zhang Y, Ran F, Liu J, Lin J, Hao
X, Ding L and Ye Q: Let-7a-5p inhibits triple-negative breast tumor
growth and metastasis through GLUT12-mediated warburg effect.
Cancer Lett. 495:53–65. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Brahimi-Horn MC, Chiche J and Pouyssegur
J: Hypoxia and cancer. J Mol Med (Berl). 85:1301–1307. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Adams JM, Difazio LT, Rolandelli RH, Luján
JJ, Haskó G, Csóka B, Selmeczy Z and Németh ZH: HIF-1: A key
mediator in hypoxia. Acta Physiol Hung. 96:19–28. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Nepal M, Choi HJ, Choi BY, Kim SL, Ryu JH,
Kim DH, Lee YH and Soh Y: Anti-angiogenic and anti-tumor activity
of Bavachinin by targeting hypoxia-inducible factor-1α. Eur J
Pharmacol. 691:28–37. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Xu L, Huan L, Guo T, Wu Y, Liu Y, Wang Q,
Huang S, Xu Y, Liang L and He X: LncRNA SNHG11 facilitates tumor
metastasis by interacting with and stabilizing HIF-1α. Oncogene.
39:7005–7018. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Shi Z, Li G, Li Z, Liu J and Tang Y:
TMEM161B-AS1 suppresses proliferation, invasion and glycolysis by
targeting miR-23a-3p/HIF1AN signal axis in oesophageal squamous
cell carcinoma. J Cell Mol Med. 25:6535–6549. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhao Q, Zhu Z, Xiao W, Zong G, Wang C,
Jiang W, Li K, Shen J, Guo X, Cui J, et al: Hypoxia-induced
circRNF13 promotes the progression and glycolysis of pancreatic
cancer. Exp Mol Med. 54:1940–1954. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Xia X, Wang S, Ni B, Xing S, Cao H, Zhang
Z, Yu F, Zhao E and Zhao G: Hypoxic gastric cancer-derived exosomes
promote progression and metastasis via MiR-301a-3p/PHD3/HIF-1α
positive feedback loop. Oncogene. 39:6231–6244. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Jin L and Zhou Y: Crucial role of the
pentose phosphate pathway in malignant tumors. Oncol Lett.
17:4213–4221. 2019.PubMed/NCBI
|
|
51
|
Polat IH, Tarrado-Castellarnau M, Bharat
R, Perarnau J, Benito A, Cortés R, Sabatier P and Cascante M:
Oxidative pentose phosphate pathway enzyme 6-phosphogluconate
dehydrogenase plays a key role in breast cancer metabolism. Biology
(Basel). 10:852021.PubMed/NCBI
|
|
52
|
Lu M, Lu L, Dong Q, Yu G, Chen J, Qin L,
Wang L, Zhu W and Jia H: Elevated G6PD expression contributes to
migration and invasion of hepatocellular carcinoma cells by
inducing epithelial-mesenchymal transition. Acta Biochim Biophys
Sin (Shanghai). 50:370–380. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Chen B, Cai T, Huang C, Zang X, Sun L, Guo
S, Wang Q, Chen Z, Zhao Y, Han Z, et al: G6PD-NF-κB-HGF signal in
gastric cancer-associated mesenchymal stem cells promotes the
proliferation and metastasis of gastric cancer cells by
upregulating the expression of HK2. Front Oncol. 11:6487062021.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Chen B, Hong Y, Gui R, Zheng H, Tian S,
Zhai X, Xie X, Chen Q, Qian Q, Ren X, et al: N6-methyladenosine
modification of circ_0003215 suppresses the pentose phosphate
pathway and malignancy of colorectal cancer through the
miR-663b/DLG4/G6PD axis. Cell Death Dis. 13:8042022. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Yuan M, Zhang X, Yue F, Zhang F, Jiang S,
Zhou X, Lv J, Zhang Z, Sun Y, Chen Z, et al: CircNOLC1 promotes
colorectal cancer liver metastasis by interacting with AZGP1 and
sponging miR-212-5p to regulate reprogramming of the oxidative
pentose phosphate pathway. Adv Sci (Weinh). 10:e22052292023.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Li Z, He Y, Li Y, Li J, Zhao H, Song G,
Miyagishi M, Wu S and Kasim V: NeuroD1 promotes tumor cell
proliferation and tumorigenesis by directly activating the pentose
phosphate pathway in colorectal carcinoma. Oncogene. 40:6736–6747.
2021. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Tseng CW, Kuo WH, Chan SH, Chan HL, Chang
KJ and Wang LH: Transketolase regulates the metabolic switch to
control breast cancer cell metastasis via the α-ketoglutarate
signaling pathway. Cancer Res. 78:2799–2812. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li
K, Shi W, Ding C, Qin L and He F: Transketolase (TKT) activity and
nuclear localization promote hepatocellular carcinoma in a
metabolic and a non-metabolic manner. J Exp Clin Cancer Res.
38:1542019. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Li M, Zhao X, Yong H, Xu J, Qu P, Qiao S,
Hou P, Li Z, Chu S, Zheng J and Bai J: Transketolase promotes
colorectal cancer metastasis through regulating AKT
phosphorylation. Cell Death Dis. 13:992022. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Zhang J, Li Z, Liu L, Wang Q, Li S, Chen
D, Hu Z, Yu T, Ding J, Li J, et al: Long noncoding RNA TSLNC8 is a
tumor suppressor that inactivates the interleukin-6/STAT3 signaling
pathway. Hepatology. 67:171–187. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Zeng X, Guo H, Liu Z, Qin Z, Cong Y, Ren
N, Zhang Y and Zhang N: S100A11 activates the pentose phosphate
pathway to induce malignant biological behaviour of pancreatic
ductal adenocarcinoma. Cell Death Dis. 13:5682022. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Anderson NM, Mucka P, Kern JG and Feng H:
The emerging role and targetability of the TCA cycle in cancer
metabolism. Protein Cell. 9:216–237. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Woolbright BL, Rajendran G, Harris RA and
Taylor JA III: Metabolic flexibility in cancer: Targeting the
pyruvate dehydrogenase kinase: Pyruvate dehydrogenase axis. Mol
Cancer Ther. 18:1673–1681. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Wang G, Liu X, Xie J, Meng J and Ni X:
PDK-1 mediated Hippo-YAP-IRS2 signaling pathway and involved in the
apoptosis of non-small cell lung cancer cells. Biosci Rep.
39:BSR201820992019. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Sun J, Feng M, Zou H, Mao Y and Yu W:
Circ_0000284 facilitates the growth, metastasis and glycolysis of
intrahepatic cholangiocarcinoma through miR-152-3p-mediated PDK1
expression. Histol histopathol. 38:1129–1143. 2022.PubMed/NCBI
|
|
66
|
Wu K, Wang Z, Huang Y, Yao L, Kang N, Ge
W, Zhang R and He W: LncRNA PTPRG-AS1 facilitates glycolysis and
stemness properties of esophageal squamous cell carcinoma cells
through miR-599/PDK1 axis. J Gastroenterol Hepatol. 37:507–517.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
He Z, Li Z, Zhang X, Yin K, Wang W, Xu Z,
Li B, Zhang L, Xu J, Sun G, et al: MiR-422a regulates cellular
metabolism and malignancy by targeting pyruvate dehydrogenase
kinase 2 in gastric cancer. Cell Death Dis. 9:5052018. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Martin-Perez M, Urdiroz-Urricelqui U,
Bigas C and Benitah SA: The role of lipids in cancer progression
and metastasis. Cell Metab. 34:1675–1699. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Bian X, Liu R, Meng Y, Xing D, Xu D and Lu
Z: Lipid metabolism and cancer. J Exp Med. 218:e202016062021.
View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Cheng C, Geng F, Cheng X and Guo D: Lipid
metabolism reprogramming and its potential targets in cancer.
Cancer Commun (Lond). 38:272018.PubMed/NCBI
|
|
71
|
Carbonetti G, Wilpshaar T, Kroonen J,
Studholme K, Converso C, d'Oelsnitz S and Kaczocha M: FABP5
coordinates lipid signaling that promotes prostate cancer
metastasis. Sci Rep. 9:189442019. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Yu CW, Liang X, Lipsky S, Karaaslan C,
Kozakewich H, Hotamisligil GS, Bischoff J and Cataltepe S: Dual
role of fatty acid-binding protein 5 on endothelial cell fate: A
potential link between lipid metabolism and angiogenic responses.
Angiogenesis. 19:95–106. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Ohata T, Yokoo H, Kamiyama T, Fukai M,
Aiyama T, Hatanaka Y, Hatanaka K, Wakayama K, Orimo T, Kakisaka T,
et al: Fatty acid-binding protein 5 function in hepatocellular
carcinoma through induction of epithelial-mesenchymal transition.
Cancer Med. 6:1049–1061. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Wang G, Bonkovsky HL, de Lemos A and
Burczynski FJ: Recent insights into the biological functions of
liver fatty acid binding protein 1. J Lipid Res. 56:2238–2247.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Lin YX, Wu XB, Zheng CW, Zhang QL, Zhang
GQ, Chen K, Zhan Q and An FM: Mechanistic investigation on the
regulation of FABP1 by the IL-6/miR-603 signaling in the
pathogenesis of hepatocellular carcinoma. Biomed Res Int.
2021:85796582021. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Wang H, Chen Y, Liu Y, Li Q, Luo J, Wang
L, Chen Y, Sang C, Zhang W, Ge X, et al: The lncRNA ZFAS1 regulates
lipogenesis in colorectal cancer by binding polyadenylate-binding
protein 2 to stabilize SREBP1 mRNA. Mol Ther Nucleic Acids.
27:363–374. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Yu Y, Dong JT, He B, Zou YF, Li XS, Xi CH
and Yu Y: LncRNA SNHG16 induces the SREBP2 to promote lipogenesis
and enhance the progression of pancreatic cancer. Future Oncol.
15:3831–3844. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Wang H, Zhang Y, Guan X, Li X, Zhao Z, Gao
Y, Zhang X and Chen R: An integrated transcriptomics and proteomics
analysis implicates lncRNA MALAT1 in the regulation of lipid
metabolism. Mol Cell Proteomics. 20:1001412021. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Corn KC, Windham MA and Rafat M: Lipids in
the tumor microenvironment: From cancer progression to treatment.
Prog Lipid Res. 80:1010552020. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Che G, Wang W, Wang J, He C, Yin J, Chen
Z, He C, Wang X, Yang Y and Liu J: Sulfotransferase SULT2B1
facilitates colon cancer metastasis by promoting SCD1-mediated
lipid metabolism. Clin Transl Med. 14:e15872024. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Li H, Chen Z, Zhang Y, Yuan P, Liu J, Ding
L and Ye Q: MiR-4310 regulates hepatocellular carcinoma growth and
metastasis through lipid synthesis. Cancer Lett. 519:161–171. 2021.
View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Wu Y, Zhou Y, Gao H, Wang Y, Cheng Q, Jian
S, Ding Q, Gu W, Yao Y, Ma J, et al: LYAR promotes colorectal
cancer progression by upregulating FSCN1 expression and fatty acid
metabolism. Oxid Med Cell Longev. 2021:99797072021. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Li X, Luo J, Mou K, Peng L, Zhou H, Lei Y,
Wang H, Zhao Z, Wang J, Wu J, et al: SDPR inhibits TGF-β induced
cancer metastasis through fatty acid oxidation regulation in
gastric cancer. Int J Biol Sci. 19:2999–3014. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Zhao P, Yuan F, Xu L, Jin Z, Liu Y, Su J,
Yuan L, Peng L, Wang C and Zhang G: HKDC1 reprograms lipid
metabolism to enhance gastric cancer metastasis and cisplatin
resistance via forming a ribonucleoprotein complex. Cancer Lett.
569:2163052023. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Choi YK and Park KG: Targeting glutamine
metabolism for cancer treatment. Biomol Ther (Seoul). 26:19–28.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
De Vitto H, Perez-Valencia J and
Radosevich JA: Glutamine at focus: Versatile roles in cancer.
Tumour Biol. 37:1541–1558. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Wu B, Chen Y, Chen Y, Xie X, Liang H, Peng
F and Che W: Circ_0001273 downregulation inhibits the growth,
migration and glutamine metabolism of esophageal cancer cells via
targeting the miR-622/SLC1A5 signaling axis. Thorac Cancer.
13:1795–1805. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Qian CJ, Tong YY, Wang YC, Teng XS and Yao
J: Circ_0001093 promotes glutamine metabolism and cancer
progression of esophageal squamous cell carcinoma by targeting
miR-579-3p/glutaminase axis. J Bioenerg Biomembr. 54:119–134. 2022.
View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Coloff JL, Murphy JP, Braun CR, Harris IS,
Shelton LM, Kami K, Gygi SP, Selfors LM and Brugge JS: Differential
glutamate metabolism in proliferating and quiescent mammary
epithelial cells. Cell metabolism. 23:867–880. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Zhou X, Liu K, Cui J, Xiong J, Wu H, Peng
T and Guo Y: Circ-MBOAT2 knockdown represses tumor progression and
glutamine catabolism by miR-433-3p/GOT1 axis in pancreatic cancer.
J Exp Clin Cancer Res. 40:1242021. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Li W, Chen C, Zhao X, Ye H, Zhao Y, Fu Z,
Pan W, Zheng S, Wei L, Nong T, et al: HIF-2α regulates
non-canonical glutamine metabolism via activation of PI3K/mTORC2
pathway in human pancreatic ductal adenocarcinoma. J Cell Mol Med.
21:2896–2908. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Li Y, Li B, Xu Y, Qian L, Xu T, Meng G, Li
H, Wang Y, Zhang L, Jiang X, et al: GOT2 silencing promotes
reprogramming of glutamine metabolism and sensitizes hepatocellular
carcinoma to glutaminase inhibitors. Cancer Res. 82:3223–3235.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Ghosh P, Vidal C, Dey S and Zhang L:
Mitochondria Targeting as an Effective Strategy for Cancer Therapy.
Int J Mol Sci. 21:33632020. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Fu H, Zhang J, Chen H, Hou H, Chen H, Xie
R, Chen Y, Zhang J, Liu D, Yan L, et al: NPR1 promotes lipid
droplet lipolysis to enhance mitochondrial oxidative
phosphorylation and fuel gastric cancer metastasis. Adv Sci
(Weinh). 37:e032332025. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Yang T, Liang N, Zhang J, Bai Y, Li Y,
Zhao Z, Chen L, Yang M, Huang Q, Hu P, et al: OCTN2 enhances
PGC-1α-mediated fatty acid oxidation and OXPHOS to support stemness
in hepatocellular carcinoma. Metabolism. 147:1556282023. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Mookerjee SA, Gerencser AA, Nicholls DG
and Brand MD: Quantifying intracellular rates of glycolytic and
oxidative ATP production and consumption using extracellular flux
measurements. J Biol Chem. 293:12649–12652. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Lissanu Deribe Y, Sun Y, Terranova C, Khan
F, Martinez-Ledesma J, Gay J, Gao G, Mullinax RA, Khor T, Feng N,
et al: Mutations in the SWI/SNF complex induce a targetable
dependence on oxidative phosphorylation in lung cancer. Nat Med.
24:1047–1057. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Wang T, Sun F, Li C, Nan P, Song Y, Wan X,
Mo H, Wang J, Zhou Y, Guo Y, et al: MTA1, a novel ATP synthase
complex modulator, enhances colon cancer liver metastasis by
driving mitochondrial metabolism reprogramming. Adv Sci (Weinh).
10:e23007562023. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Liu Y, Tian W, Ge C, Zhang C, Huang Z,
Zhang C, Yang Y and Tian H: SNX17 mediates STAT3 activation to
promote hepatocellular carcinoma progression via a retromer
dependent mechanism. Int J Biol Sci. 21:2762–2779. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Wang YN, Zeng ZL, Lu J, Wang Y, Liu ZX, He
MM, Zhao Q, Wang ZX, Li T, Lu YX, et al: CPT1A-mediated fatty acid
oxidation promotes colorectal cancer cell metastasis by inhibiting
anoikis. Oncogene. 37:6025–6040. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Xu R, Liu Y, Ma L, Sun Y, Liu H, Yang Y,
Jin T and Yang D: NQO1/CPT1A promotes the progression of pancreatic
adenocarcinoma via fatty acid oxidation. Acta Biochim Biophys Sin
(Shanghai). 55:758–768. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Sun M, Yue Y, Wang X, Feng H, Qin Y, Chen
M, Wang Y and Yan S: ALKBH5-mediated upregulation of CPT1A promotes
macrophage fatty acid metabolism and M2 macrophage polarization,
facilitating malignant progression of colorectal cancer. Exp Cell
Res. 437:1139942024. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Hayes JD, Dinkova-Kostova AT and Tew KD:
Oxidative stress in cancer. Cancer Cell. 38:167–197. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Zeng Q, Lv C, Qi L, Wang Y, Hao S, Li G,
Sun H, Du L, Li J, Wang C, et al: Sodium selenite inhibits cervical
cancer progression via ROS-mediated suppression of glucose
metabolic reprogramming. Life Sci. 357:1231092024. View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Castelli S, De Falco P, Ciccarone F,
Desideri E and Ciriolo MR: Lipid Catabolism and ROS in Cancer: A
Bidirectional Liaison. Cancers (Basel). 13:54842021. View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Tiwari R, Mondal Y, Bharadwaj K, Mahajan
M, Mondal S and Sarkar A: Reactive Oxygen Species (ROS) and their
profound influence on regulating diverse aspects of cancer: A
concise review. Drug Dev Res. 86:e701072025. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Li D, Wang Y, Dong C, Chen T, Dong A, Ren
J, Li W, Shu G, Yang J, Shen W, et al: CST1 inhibits ferroptosis
and promotes gastric cancer metastasis by regulating GPX4 protein
stability via OTUB1. Oncogene. 42:83–98. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Di Gregorio J, Petricca S, Iorio R,
Toniato E and Flati V: Mitochondrial and metabolic alterations in
cancer cells. Eur J Cell Biol. 101:1512252022. View Article : Google Scholar : PubMed/NCBI
|
|
109
|
Vasan K, Werner M and Chandel NS:
Mitochondrial metabolism as a target for cancer therapy. Cell
Metab. 32:341–352. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Pajak B, Siwiak E, Sołtyka M, Priebe A,
Zieliński R, Fokt I, Ziemniak M, Jaśkiewicz A, Borowski R,
Domoradzki T and Priebe W: 2-Deoxy-d-Glucose and its analogs: From
diagnostic to therapeutic agents. Int J Mol Sci. 21:2342019.
View Article : Google Scholar : PubMed/NCBI
|
|
111
|
Luo W, Guo S, Zhou Y, Zhu J, Zhao J, Wang
M, Sang L, Wang B and Chang B: Hepatocellular carcinoma: Novel
understandings and therapeutic strategies based on bile acids
(Review). Int J Oncol. 61:1172022. View Article : Google Scholar : PubMed/NCBI
|
|
112
|
Gagnière J, Raisch J, Veziant J, Barnich
N, Bonnet R, Buc E, Bringer MA, Pezet D and Bonnet M: Gut
microbiota imbalance and colorectal cancer. World J Gastroenterol.
22:501–518. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
113
|
Behnam B and Taghizadeh-Hesary F:
Mitochondrial metabolism: A new dimension of personalized oncology.
Cancers (Basel). 15:40582023. View Article : Google Scholar : PubMed/NCBI
|
