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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2025 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

SBEM confers paclitaxel resistance in breast cancer via DUSP16‑mediated MAPK/AMPK pathway activation

Liang Liu, Ning Lu, Xiaomei Liu, Qingting Yi, Shengnan Li, Jie Wen, Huijuan Sun, Yuanming Du
Article Number: 607
Published online on: 21 October 2025

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Article Open Access

Role and molecular mechanisms of hypoxia‑derived exosomal miR‑301a on gemcitabine resistance in pancreatic cancer

Weiwei Qu, Wanyi Tan, Mengjie Ye, Weixiang Tang, Lijun Zhang, Guangtao Luo
Article Number: 606
Published online on: 21 October 2025

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Case Report

Multiple primary malignant neoplasms and long‑term survival: A case report

Biao Xie, Ke Huang, Shuibo Zhu
Article Number: 605
Published online on: 21 October 2025

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Article Open Access

m6A RNA methylation regulator‑associated genes drive metastasis and immune cell infiltration in skin cutaneous melanoma

Yi Geng, Sijia Zhao, Tianxiang Geng, Xiu-Lian Xu, Xiaodie Zhang
Article Number: 604
Published online on: 21 October 2025

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Article Open Access

Analysis of the efficacy and prognostic factors of gemcitabine combined with oxaliplatin in non‑Hodgkin lymphoma

Xiaobo Zhang, Guang Li, Feng Liu, Rui Shi, Jing Wen, Wen Wu, Jinqian Dai
Article Number: 603
Published online on: 21 October 2025

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Article Open Access

Stimulator of interferon genes signaling network‑driven prognostic signature for pancreatic cancer: Hub gene discovery with multimodal validation

Wenjing Yu, Junqun Liao, Jiayan Li, Yongquan Wu
Article Number: 602
Published online on: 21 October 2025

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Article Open Access

Gamma Knife consolidation therapy improves prognosis in patients with advanced epidermal growth factor receptor‑mutant lung adenocarcinoma treated with first‑generation epidermal growth factor receptor‑tyrosine kinase inhibitors

Bin Xu, Donghui Lu, Dongmei Wang, Huan Ma, Zhijie Li, Lijie Zhang, Meiqin Liu, Donglai Lv
Article Number: 601
Published online on: 17 October 2025

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Article Open Access

Identification of EFNA3 as candidate prognosis marker and potential therapeutic target for adrenocortical carcinoma

Yanghao Tai, Xinzhe Liu, Yifan Zhou, Jiwen Shang
Article Number: 600
Published online on: 17 October 2025

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Article Open Access

Inhibition of apoptosis in breast cancer cells by si‑FoxO3a through the protein digestion and absorption signaling pathway

Liying Sun, Zhongxu Wang, Yanxi Liu, Jiaxin Lv, Xiaotong Shao, Haoming Tang, Cheng Hu, Liang Cao, Yundong Zhao, Shuang Chen
Article Number: 599
Published online on: 17 October 2025

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Review Open Access

CCL2/CCR2 signaling pathway in tumorigenesis and metastasis (Review)

Ya Zhang, Bin Fan, Hang Yang, Gangxian Chen, Zhou Huang, Ying Li, Xiang Ma, Tiying Wang, Weiquan Wang, Linhao Cai, Lei Han, Yan Liu, Dongqi Li, Xianwei Chen, Yihao Yang, Zuozhang Yang
Article Number: 598
Published online on: 17 October 2025

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Article Open Access

Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma Corrigendum in /10.3892/ol.2026.15489

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 597
Published online on: 16 October 2025

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Case Report Open Access

Submandibular adenoid cystic carcinoma presenting with liver metastasis as the initial symptom: A case report

Tianyi Li, Tingyao Ma, Yue Zhao, Shujing Zhang, Guoliang Yang, Xuelian Wang, Xudong Wang, Mingzhu Wang, Xi Zhao, Hongfei Liu, Jun Wu, Xiaoli Zhao, Xiaohong Chen
Article Number: 596
Published online on: 15 October 2025

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Case Report Open Access

Esophageal perforation in a patient with lung cancer after administration of bevacizumab combined with radiotherapy and chemotherapy: A case report

Qiang Jia, Yun-Long Zhou, Lan-Ying Duan, Hui-Chao Li, Gaowu Hu
Article Number: 595
Published online on: 15 October 2025

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Case Report

Gastrointestinal metastasis in prostate cancer and therapeutic implications: A case report

Marie-Anne Audisio, Anh-Tuan Nguyen, Evelyne Peroux, Jean-Laurent Lamboley, David Lussato, Marie Pautas, Hugo Picchi, Audrey Le Roy, Aline Barhli, Marie Dusaud, Hélène Vanquaethem, Antoine Schernberg, Carole Helissey
Article Number: 594
Published online on: 15 October 2025

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Review Open Access

Advancements in research on the role of the key glycolytic enzyme hexokinase 2 in the regulation of tumor immune evasion (Review)

Yiyang Qian, Xiaodan Zhu, Dong Niu, Quan Tang, Chunhui Jin
Article Number: 593
Published online on: 14 October 2025

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Review Open Access

Cellular senescence in cancer: Unveiling dual roles, tumor microenvironment dynamics and therapeutic innovations (Review)

Yatsu Lam, Jiaming Gu, Peihao Yin
Article Number: 592
Published online on: 14 October 2025

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Article Open Access

A novel defined cuproptosis‑related signature score to predict prognosis and immunotherapy efficacy in pancreatic cancer

Weiyu Ge, Yongchao Wang, Daiyuan Shentu, Ming Yue, Yanling Wang
Article Number: 591
Published online on: 14 October 2025

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Article Open Access

Multi‑omics and experimental validation unveil BDNF as a diagnostic biomarker and therapeutic target in endoplasmic reticulum stress‑driven lung adenocarcinoma: Therapeutic potential of Esketamine

Xiujuan Deng, Yujun Tan, Guangbo Tan, Heli Ning
Article Number: 590
Published online on: 14 October 2025

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Review Open Access

Role of signaling pathways in lung cancer development and advances in targeted therapies (Review)

Zhang Tao, Weiwei Shao, Haiyang Zhou, Shujing Xia, Jie Zeng, Jing Ren, Xueyang Wang, Hua Zhu
Article Number: 589
Published online on: 14 October 2025

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Article Open Access

Bortezomib overcomes TRAIL resistance in Burkitt's lymphoma by enhancing apoptosis via reactive oxygen species‑mediated DR5 upregulation and MAPK pathway activation

Jiajie Chen, Yujia You, Wei Zhao, Yichuan Zhou, Shiqi Pu, Xiaoyu Bai, Ping Yang, Minhui Li
Article Number: 588
Published online on: 14 October 2025

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Article Open Access

Prognostic role and mutational characteristics of N6‑methyladenosine‑related genes in lung adenocarcinoma

Jiahao Yang, Xiangpeng Chu, Zihao Chen, Yi Long, Jinghua Chen
Article Number: 587
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Nerve growth factor and its receptors on onset and diagnosis of ovarian cancer

Xiaolin Yu, Zhaoxia Liu, Rui Hou, Yijun Nie, Rensheng Chen
Article Number: 586
Published online on: 13 October 2025

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Case Report

Severe fluoropyrimidine toxicity in a patient with rectal adenocarcinoma with DPYD c.2846A>T heterozygous mutation: A case report

Sezai Tunc, Ogur Karhan
Article Number: 585
Published online on: 13 October 2025

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Article

Prognostic value of the postoperative CALLY index in T1/T2 clear cell renal cell carcinoma

Hiroshi Hirata, Nakanori Fujii, Takanori Tokunaga, Kosuke Shimizu, Keita Kobayashi, Koji Shiraishi
Article Number: 584
Published online on: 10 October 2025

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Review

Role and mechanistic study of long non‑coding RNA maternally expressed gene 3 in gastric cancer (Review)

Buyun Jia, Hui Cheng, Peizheng Yang, Xiangyu Wang, Shanshan Li, Jinghui Wang
Article Number: 583
Published online on: 10 October 2025

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Article Open Access

Survival and recurrence characteristics of patients with esophageal cancer with a pathological complete response after neoadjuvant immunochemotherapy followed by surgery: A multicenter propensity score matching study

Feng Wang, Xiangyang Yu, Dongjie Yan, Lei Yang, Jianfei Zhu, Ran Yang, Yi Han
Article Number: 582
Published online on: 10 October 2025

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Article

Machine learning‑based programmed cell death‑related index to predict prognosis and immunotherapy response in skin cutaneous melanoma

Xinyi Wang, Yuzhi Zheng, Shan Yang, Hongli Si, Wenqiu Chen, Siyuan Shen
Article Number: 581
Published online on: 09 October 2025

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Correction Open Access

[Corrigendum] UBE2T silencing suppresses proliferation and induces cell cycle arrest and apoptosis in bladder cancer cells

Yan Qing Gong, Ding Peng, Xiang Hui Ning, Xin Yu Yang, Xue Song Li, Li Qun Zhou, Ying Lu Guo
Article Number: 580
Published online on: 09 October 2025

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Article Open Access

Dynamic changes in tumor blood flow during chemotherapy: Implications in customized treatment for pancreatic cancer

Hiromitsu Maehira, Takeru Maekawa, Yoshihisa Tsuji, Haruki Mori, Nobuhito Nitta, Takeshi Sonoda, Reiko Otake, Soichiro Tani, Katsushi Takebayashi, Masatsugu Kojima, Sachiko Kaida, Toru Miyake, Masaji Tani
Article Number: 579
Published online on: 08 October 2025

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Review Open Access

Abnormal metabolic networks participate in invasion and migration of tumors of the digestive system (Review)

Jianxin Li, Weidong Zhang
Article Number: 578
Published online on: 08 October 2025

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Article Open Access

A clinical feature‑based nomogram for the personalized prediction of radioactive iodine therapy outcomes in patients with papillary thyroid carcinoma

Jingjia Cao, Huazhen Liang, Xiang Li, Xin Guan, Hao Xu
Article Number: 577
Published online on: 07 October 2025

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Review Open Access

Immune checkpoint biology in hepatocellular carcinoma (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 576
Published online on: 07 October 2025

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Article Open Access

Preoperative PD‑1+CD4+ lymphocytes reflect immunological and physical frailty and are associated with postoperative infectious complications following gastrectomy for gastric cancer

Naoyuki Uehata, Hironori Tsujimoto, Nozomi Ito, Toru Kubo, Hiromi Miyazaki, Hiroyuki Horiguchi, Keita Kouzu, Seiichiro Fujishima, Takafumi Suzuki, Risa Kariya, Asuma Ide, Yoshihisa Yaguchi, Hideki Ueno
Article Number: 575
Published online on: 07 October 2025

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Case Report Open Access

Primary retroperitoneal squamous cell carcinoma: A case report

Fang Zhang, Yuan Gui, Jing Zhang
Article Number: 574
Published online on: 06 October 2025

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Case Report

Papillary thyroid carcinoma with metastasis to the femur as a rare cause of femoral fracture: A case report

Jiahua Chen, Mi Zhang
Article Number: 573
Published online on: 06 October 2025

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Retraction Open Access

[Retracted] Effect of interventional embolotherapy on FHIT and p16 expression in hepatocellular carcinoma patients

Wei Xu, Xiaogai Qi, Xia Wang, Jize Sun
Article Number: 572
Published online on: 06 October 2025

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Article Open Access

GBP5 as a prognostic biomarker associated with immune cell infiltration, migration and invasion in clear cell renal cell carcinoma

Xiaobao Cheng, Shujiang Ye, Xiang Xu, Shuo Yang, Wei Zhao, Zhenquan Lu, Caiyong Lai
Article Number: 571
Published online on: 03 October 2025

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Article Open Access

FBXL22, a circadian‑regulated immune biomarker with pan‑cancer prognostic value and therapeutic potential in prostate cancer

Jin Liu, Maoyuan Feng, Jian Zhou, Shijie Yang, Yue Shi, Wenping Li
Article Number: 570
Published online on: 03 October 2025

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Article Open Access

Deciphering site‑specific histopathological parameters with potential clinical value in head and neck squamous cell carcinomas

Sofia-Eleni Tzorakoleftheraki, Vassiliki Kotoula, Georgios Karakatsoulis, Konstantinos Markou, Stavroula Pervana, Konstantinos Vlachtsis, Sofia Chrisafi, Amanda Psyrri, George Fountzilas, Prodromos Hytiroglou, Triantafyllia Koletsa
Article Number: 569
Published online on: 03 October 2025

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Article Open Access

Non‑surgical breast‑conserving treatment using Kochi oxydol‑radiation therapy for unresectable carcinomas II for patients with stage 0 to IIIC breast cancer

Akihiro Hori, Taiju Shimbo, Jun Ikenaga, Takaaki Itami, Mari Mukai, Kazuma Kobata, Takashi Ogawa, Ayaka Kihara, Mio Nakata, Yuuki Yoshino, Satoshi Takeno, Kanabu Nawa, Hiroto Yoshioka, Keiji Nihei, Hironori Akiyama, Ken Yoshida, Kosei Kimura, Mitsuhiko Iwamoto
Article Number: 568
Published online on: 02 October 2025

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Review Open Access

Pathogenic role and therapeutic targets of nuclear factor‑κB signaling pathway in cancer (Review)

Xing Li, Lu Chen, Ming Zeng, Jialun Deng, Fan Chen, Lingying Yu, Mingyue Ao
Article Number: 567
Published online on: 02 October 2025

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Case Report Open Access

Multimodal treatment for multifocal metastatic maxillary adenoid cystic carcinoma: A case report

Bin He, Jie Shi, Qing-Yan Yan, Ling Zhang
Article Number: 566
Published online on: 01 October 2025

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Review Open Access

Roles of β‑catenin protein in non‑small cell lung cancer (Review)

Lina Peng, Ran Gao, Liping Han, Tian Fu, Cuixia Bian
Article Number: 565
Published online on: 01 October 2025

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Article Open Access

Application value and safety of trilaciclib in first‑line chemotherapy combined with immunotherapy for extensive‑stage small cell lung cancer: A real‑world study

Yanping Cui, Hongjuan Zhang, Lizhi Wang, Xingyi Lou
Article Number: 564
Published online on: 01 October 2025

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Case Report Open Access

Multicentric Castleman disease detected during the evaluation of tongue cancer: A case report

Yuta Yasui, Satoshi Shimohama, Manabu Yamada, Kenichiro Suga, Masafumi Nishikawa, Seiji Asoda
Article Number: 563
Published online on: 01 October 2025

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Case Report Open Access

Sequential microwave ablation combined with radioactive iodine‑125 seed implantation successfully cured multiple metastases of gallbladder cancer: A case report

Wenjun Li, Yanwei Chen, Shuangshuang Zhao, Maohui An, Huajiao Zhao, Yun Cai, Jiayan Bao, Jiwen Qian, Baoding Chen
Article Number: 562
Published online on: 01 October 2025

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Article Open Access

Signature of immune infiltration‑related ferroptosis genes to predict the prognosis of patients with osteosarcoma

Ling-Rong Zeng, Guang-Hui Zhu, Hai-Bo Mei, Ge Yang
Article Number: 561
Published online on: 01 October 2025

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Article Open Access

Anticancer effects of the Kiperin Purple Collagen complex: Evidence from HCT116 and MIA PaCa‑2 cell models

Lutfiye Karcioglu Batur, Cuneyd Yavas, Nezih Hekim
Article Number: 560
Published online on: 01 October 2025

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Expression of Concern Open Access

[Expression of Concern] microRNA‑99a is downregulated and promotes proliferation, migration and invasion in non‑small cell lung cancer A549 and H1299 cells

Changjin Chen, Ziyi Zhao, Yu Liu, Dezhi Mu
Article Number: 559
Published online on: 01 October 2025

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Article Open Access

Leucine‑rich repeat‑containing G protein‑coupled receptor 4 promotes proliferation, invasion and migration, and inhibits apoptosis in non‑small cell lung cancer cells

Xiaoyu Duan, Xiangsen Liu, Yuchen Shan, Songfu Zhou, Ming Lou, Zhaojia Gao, Kai Yuan
Article Number: 558
Published online on: 30 September 2025

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Retraction Open Access

[Retracted] Treatment with a selenium‑platinum compound induced T‑cell acute lymphoblastic leukemia/lymphoma cells apoptosis through the mitochondrial signaling pathway

Feifei Wu, Wei Cao, Huaping Xu, Mingxia Zhu, Jing Wang, Xiaoyan Ke
Article Number: 557
Published online on: 29 September 2025

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Article Open Access

Serum fucosylated receptor expression‑enhancing protein 5 as a biomarker for early stage pancreatic cancer

Kazuyuki Sogawa, Riko Yonekubo, Momori Shimizu, Satoshi Muraoka, Jun Adachi, Shigetsugu Takano, Hirotaka Takizawa, Masayuki Ohtsuka, Takeshi Tomonaga
Article Number: 556
Published online on: 26 September 2025

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Case Report Open Access

Primary squamous thyroid cancer: A case report

Shuchang Dong, Xuewen Wang, Ziwen Zhou, Lingjun Feng, Qingliang Xu
Article Number: 555
Published online on: 26 September 2025

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Article Open Access

Transarterial infusion chemotherapy for severe hepatic dysfunction and poor performance status in diffuse hepatic metastasis: A case report

Xiao-Chun Chen, Xian-Qin Li, Yi Liu, Xu Zhang, Chuan Lin, Zhi-Ping Yuan
Article Number: 554
Published online on: 25 September 2025

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Article Open Access

Real‑world investigation for camrelizumab combined with apatinib in patients with advanced hepatocellular carcinoma

Liyang Yin, Yuanyuan Shi, Ruijia An, Yajing Hao, Haoran Huo, Jiadong Xue, Ruifeng Qin, Zengjiang Yuan
Article Number: 553
Published online on: 25 September 2025

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Article Open Access

Impact of SAMHD1 and phosphorylated ATM levels on the progression and prognosis of patients with soft tissue sarcoma

Yun Jae Kim, Young Jae Moon, Ae Ri Ahn, Ho Sung Park, Myoung Ja Chung, Woo Sung Moon, Kyu Yun Jang, Kyoung Min Kim
Article Number: 552
Published online on: 24 September 2025

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Article Open Access

Methionine‑MAT2A‑SAM axis controls lipid levels by regulating ACSL4

Chaoyi Xia, Jingshu Min
Article Number: 551
Published online on: 24 September 2025

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Article Open Access

Favorable survival of patients with nasopharyngeal carcinoma associated with metachronous multiple primary cancers: A retrospective study

Xin Huang, Ying Kong, Tianyu Wu, Zhen Meng, Min Kang
Article Number: 550
Published online on: 23 September 2025

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Article Open Access

Protein arginine methyltransferase 7 regulates the cell cycle and promotes the progression of prostate cancer

Hongyuan Wan, Hangshen Zhou, Jiandong Gui, Dongjie Yang, Rong Wang, Jiang Ni, Sheng Wu, Yan Qin, Qiaowei Qi, Lijie Zhu, Ninghan Feng, Yuanyuan Mi
Article Number: 549
Published online on: 23 September 2025

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Case Report Open Access

Adrenal cyst misdiagnosed with cystic renal cell carcinoma: A case report

Xin Huang, Mengyu Zhang, Yijun Zhan, Ce Chen, Xinhua Zhang, Yaozhong Xu
Article Number: 548
Published online on: 23 September 2025

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Correction Open Access

[Corrigendum] Characteristics of primary side population cervical cancer cells

Zhen-Tong Wei, Xiao-Wei Yu, Jia-Xue He, Yan Liu, Song-Ling Zhang
Article Number: 547
Published online on: 23 September 2025

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Article Open Access

Clinicopathological characteristics and treatment of patients with colorectal neuroendocrine carcinoma: A retrospective study of 157 cases

Meng Dai, Shuang Sun, Xin Liu, Hulun Li
Article Number: 546
Published online on: 23 September 2025

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Article Open Access

Peripheral blood tumor marker levels can indicate the location of lung cancer metastasis

Jiahao Wang, Xiaobo Wang, Yingjia Mao, Hongmei Niu, Fuqian Zhao, Daofu Shen, Lei Wang
Article Number: 545
Published online on: 23 September 2025

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Retrospective comparisons of the dosimetric differences between coplanar and non‑coplanar volume‑modulated arc therapy in patients with pediatric brainstem glioma

Zhanquan Lei, Junjie Jing, Yuequan Shi, Bo Gao, Kongfeng Shao, Yiqun Liu, Junjin Yan
Article Number: 544
Published online on: 22 September 2025

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Preoperative peripheral blood routine indicators as predictors of prognosis and diagnosis in glioma under the 2021 World Health Organization classification

Qing Yang, Jiaying Ni, Jiandong Zhu, Xiao Fan, Xing Cheng, Yun Yu, Zhumei Shi, Yingyi Wang, Yongping You
Article Number: 543
Published online on: 22 September 2025

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Case Report Open Access

Efficacy of combined immunotherapy and chemotherapy in recurrent non‑small cell lung cancer during durvalumab maintenance therapy: A case report

Yuki Maze, Takahiro Mitsumura, Hiroshi Nakahama, Tatsuya Kato, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 542
Published online on: 22 September 2025

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Efficacy and safety of fruquintinib combined with immunotherapy in later‑line treatment of metastatic colorectal cancer

Ying Peng, Sheng Li, Liangjun Zhu
Article Number: 541
Published online on: 22 September 2025

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Prognostic value of M2 macrophage‑related genes and their importance in the immunotherapy response in hepatocellular carcinoma

Aiping Wang, Xiaojing Li, Zi Wang, Lan Chen
Article Number: 540
Published online on: 22 September 2025

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Histone acetyltransferase 1 promotes ovarian cancer progression by regulating cell proliferation and the cell cycle

Xiao Han, Ling Liu, Jing Li, Yunxiao Zhi, Lanlan Zhao, Limin Yuan, Xuezhe Ouyang, Jie Liu
Article Number: 539
Published online on: 22 September 2025

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Retraction Open Access

[Retracted] MicroRNA‑320a downregulation mediates human liver cancer cell proliferation through the Wnt/β‑catenin signaling pathway

Caicheng Lu, Zengwei Liao, Minxian Cai, Guirong Zhang
Article Number: 538
Published online on: 22 September 2025

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September-2026 Volume 32 Issue 3

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article

FOXA2 enhances anoikis sensitivity in lung adenocarcinoma cells: Dual role of ABCA8 upregulation and NOX4 suppression

Nina Hu, Ling Li, Jianqing Hao, Lifang Li, Mengmeng Pan, Jia He
Article Number: 422
Published online on: 22 July 2026

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Correction Open Access

[Corrigendum] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells

Chengfei Jiang, Binbin Yuan, Bo Hang, Jian-Hua Mao, Xiaoping Zou, Pin Wang
Article Number: 421
Published online on: 21 July 2026

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Review Open Access

Neoadjuvant therapy for stage II‑III triple‑negative breast cancer: Current evidence, clinical boundaries and emerging strategies (Review)

Bingchen Li, Xinchen Tian, Qing-Qing Yu, Hongxia Cui
Article Number: 420
Published online on: 21 July 2026

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Keratin gene expression signature predicts prognosis and immunotherapy efficacy in lung adenocarcinoma

Aohui Chen, Ting Gao, Fengqi Liu, Mingyue Zhao, Ruizhen Bai, Quan Liu
Article Number: 419
Published online on: 21 July 2026

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Prognostic value of nutritional and inflammatory biomarkers in patients with non‑small cell lung cancer and bone metastasis: A retrospective study

Yuanjiao Chen, Lu Zhang, Shuting Wang, Huangren Zou, Yanlin Liu, Yuke Bai, Zhiyong Deng, Chao Liu, Suyun Yang
Article Number: 418
Published online on: 21 July 2026

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Retraction Open Access

[Retracted] Effects of FHIT gene on proliferation and apoptosis of osteosarcoma cells

Zhengfeng Xu, Jiajun Wu, Pan Cai, Xiaoxiao Zhou, Cunguo Yi, Bin Wang
Article Number: 417
Published online on: 20 July 2026

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Review

Ferroptosis regulatory networks as therapeutic sensitizers in combination therapy for hepatocellular carcinoma (Review)

Mengxiao Zhu, Xiaoxiong Hu
Article Number: 416
Published online on: 17 July 2026

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 Establishment of extrahepatic bile duct cancer organoids using suspension culture and their application in clinical drug screening

Wei Huang, Yuanhui Su, Cheng Yu, Yanlong Zhang, Hao Xu, Wence Zhou
Article Number: 415
Published online on: 17 July 2026

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Systems biology of Wnt signaling in glioma chemotherapy resistance: Integrating multi‑omics mechanisms and emerging therapeutic vulnerabilities (Review)

Qianru Zeng, Zhuojun Chen, Rendong Zhang, Hongchao Pan
Article Number: 414
Published online on: 17 July 2026

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A three‑gene signature correlated with MAPK/ERK activation characterizes acquired resistance to EGFR‑tyrosine kinase inhibitors in non‑small cell lung cancer

Changtai Qin, Wei Zhang, Dongfang Tang, Yuxi Yang, Binghui Liang, Zhiming Hu, Yuxiao Zhang, Tingjie Ye, Wei Xu
Article Number: 413
Published online on: 17 July 2026

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Review Open Access

Role of PCSK9 in hallmarks of cancer: From mechanisms to interventions (Review)

Lijuan Tang, Shu Yao, Yongheng Zhu, Zongsheng He, Bruno Ramos‑Molina, Yuanchun Xu
Article Number: 412
Published online on: 15 July 2026

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PRR11 expression in early ER+/HER2‑low breast cancer: Association with estrogen receptor positivity and exploratory analysis of prognostic significance

Alper Turkel, Mutlu Dogan, Sultan Cigdem Irkkan, Haktan Bagis Erdem, Nazan Bozdogan, Taha Bahsi
Article Number: 411
Published online on: 15 July 2026

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Expression of Concern Open Access

[Expression of Concern] Elevated microRNA‑125b levels predict a worse prognosis in HER2‑positive breast cancer patients  

Yanwei Luo, Xinye Wang, Weihong Niu, Heran Wang, Qiuyuan Wen, Songqing Fan, Ran Zhao, Zheng Li, Wei Xiong, Shuping Peng, Zhaoyang Zeng, Xiaoling Li, Guiyuan Li, Ming Tan, Ming Zhou
Article Number: 410
Published online on: 15 July 2026

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Article Open Access

Association between the presence of EGFR or ALK mutations and the location of primary non‑small cell lung cancer, as well as metabolic activity observed on 18F‑FDG PET/CT scans

Inci Uslu Biner, Tuba Inal Cengiz, Ulku Yilmaz, Nalan Akyurek, Suna Kavurgaci, Pinar Akin Kabalak, Derya Kizilgoz, Ezgi Gurel Akan
Article Number: 409
Published online on: 14 July 2026

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Review Open Access

Advances in Helicobacter pylori-mediated oncogenic signaling pathways in gastric cancer: From pathological evolution to clinical application prospects (Review)

Tingting Ding, Wenjun Hu, Xiaogai Qi, Yakun Zhang, Hui Wang
Article Number: 408
Published online on: 14 July 2026

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Article

Clinical and biological significance of TROY (TNFRSF19) splice variants in colorectal cancer

Mitsuaki Nishioka, Yuki Kunimune, Yutaka Suehiro, Masaki Kodama, Akiyo Ishiguro, Tatsuya Takagi, Jun Nishikawa, Hidenori Takahashi, Hiroto Matsui, Shinobu Tomochika, Koichi Hamabe, Shinichi Hashimoto, Hiroaki Nagano, Taro Takami, Takahiro Yamasaki
Article Number: 407
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Sirtuin 7 promotes glioma proliferation and invasion through activation of the ERK/STAT3 signaling pathway

Pengfei Mu, Kun Liu, Qingyuan Lin, Wensheng Yang, Dan Liu, Zhen Lin, Wei Shao, Tianhai Ji
Article Number: 406
Published online on: 13 July 2026

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Article

Molecular signatures of triple‑negative breast cancer cells acquiring palbociclib resistance via continuous exposure

Daichi Enomoto, Yumika Iwasa, Natsuho Irie, Haruki Ohata, Yuki Uemichi, Miyuki Mabuchi, Tadashi Shimizu, Kohji Takara
Article Number: 405
Published online on: 10 July 2026

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Review Open Access

Gastrointestinal conventional carcinoma with neuroendocrine differentiation: From pathological phenomenon to clinical importance (Review)

Chenyang Zhou, Shizheng Tong, Danfeng Zhou, Yixin Pan, Jingjing Xu, Sunbin Ling, Wei Wu, Tingting Feng
Article Number: 404
Published online on: 09 July 2026

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Cell‑cycle reactivation and hepatocyte identity loss in hepatocellular carcinoma: Transcriptomic hallmarks and validation strategies (Review)

Jichen Hou, Bing Zhu, Lu Liang
Article Number: 403
Published online on: 09 July 2026

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Case Report Open Access

Primary thymic papillary adenocarcinoma with a rare CD5/CD117‑negative and PAX8/WT1‑positive immunophenotype: A case report

Dequan Zhu, Chuanzhen Wan, Jialong Guo, Tao Zeng, Wei Wang
Article Number: 402
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Fatty acids inhibit anticancer effects of 5‑fluorouracil in mouse cancer cell lines

Eriko Tanabe, Misaho Kitayoshi, Kiyomu Fujii, Hitoshi Ohmori, Yi Luo, Yui Kadochi, Shiori Mori, Rina Fujiwara, Yukiko Nishiguchi, Takamitsu Sasaki, Hiroki Kuniyasu
Article Number: 401
Published online on: 09 July 2026

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Article Open Access

A nomogram prediction model for brain metastases in patients with lung adenocarcinoma 

Hao Liu, Lan Wang, Xiaolei Zhuo, Yucheng Hu, Ziming Li, Huishan Deng, Mingshu Mo
Article Number: 400
Published online on: 08 July 2026

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Article Open Access

Survival benefits of non‑surgical triple therapy in hepatocellular carcinoma with inferior vena cava/right atrial tumor thrombus: A retrospective analysis from a multidisciplinary team

Peng Tang, Jin Li, Jiayu Duan, Xin Wang, Jin Zhou, Yu Yang, Yong Zeng
Article Number: 399
Published online on: 08 July 2026

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Article Open Access

A bioinformatics analysis of KIF transcriptomic subtyping reveals prognostic heterogeneity and differential therapeutic responses in cervical cancer

Xinyi Zhao, Jie Wu, Lan Li, Haohan Zhang, Jing Li, Hao Zhong, Yuchao Dan, Qibin Song, Hongbin Chen, Bin Xu
Article Number: 398
Published online on: 08 July 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA OIP5‑AS1 promotes the progression of esophageal cancer by regulating miR‑30a/VOPP1 expression

Jiajun Xu, Zhixi Chen, Zheng Fang, Shixiong Chen, Ying Guo, Xianfeng Liu, Kai Chen, Shengjia Chen
Article Number: 397
Published online on: 08 July 2026

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Article Open Access

FUBP3 regulates expression and alternative splicing of genes associated with cell proliferation and apoptosis in cancer cells

Lingyu Kong, Chaoxu Fu, Xuesong Li, Mingxin Chen, Xinqi Liu, Min Zhou, Tongshu Wang, Hongxin Piao
Article Number: 396
Published online on: 07 July 2026

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Article

Pan‑immune‑inflammation value as a prognostic and predictive biomarker in metastatic non‑small cell lung cancer treated with nivolumab: A real‑world study

Nedim Turan, Hacer Sahika Yildiz, Sedat Yildirim, Ezgi Turkoglu, Ugur Ozkerim, Sila Oksuz, Neslihan Buyukmurat, Hamit Bal, Heves Surmeli, Hatice Odabas
Article Number: 395
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] miR‑5590‑3p inhibits the proliferation and metastasis of renal cancer cells by targeting ROCK2 to inhibit proliferation, migration and invasion

Queling Liu, Anyi Zhu, Weiyin Gao, Fu Gui, Yan Zou, Xiaocheng Zhou, Zhengdong Hong
Article Number: 394
Published online on: 06 July 2026

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Article

Logistic regression analysis of risk factors for abdominal adhesion during hyperthermic intraperitoneal chemotherapy for ovarian cancer

Jinfen Yao, Jie Chen
Article Number: 393
Published online on: 03 July 2026

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Review Open Access

Regulatory roles of N6‑methyladenosine methylation factors in melanoma invasion and metastasis (Review)

Zhijie Xu, Wanqun Yu, Jie Liu, Xiyue Chang, Shiraz Manji Laeeqa, Zerong Xu, Qi Yang, Wanan Xiao
Article Number: 392
Published online on: 03 July 2026

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Review

Microbiota in pancreatic cancer: Roles in tumor initiation and progression (Review)

Yanjun Lou, Yiqun Fan
Article Number: 391
Published online on: 03 July 2026

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Review Open Access

Role of long non‑coding RNA HCG11 in human cancers: From molecular mechanisms to clinical applications (Review)

Qiong-Feng Tan, Bo Chen, Hai-Feng Hu, Huang Liu, Wen Huang, Wei Mu
Article Number: 390
Published online on: 03 July 2026

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Expression of Concern Open Access

[Expression of Concern] Endosialin/CD248 may be a potential therapeutic target to prevent the invasion and metastasis in osteosarcoma

Yumiko Kondo, Kanya Honoki, Shingo Kishi, Shiori Mori, Rina Fujiwara‑Tani, Shinji Tsukamoto, Hiromasa Fujii, Hiroki Kuniyasu, Yasuhito Tanaka
Article Number: 389
Published online on: 03 July 2026

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Review Open Access

Emerging roles of O‑GlcNAcylation in tumorigenesis, immunosuppression and drug resistance (Review)

Yuntong Liu, Yumo Han, Shumei Ding, Han Deng, Shiyue Li, Yingyu Zhang, Haimeng Yin, Bo You
Article Number: 388
Published online on: 02 July 2026

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Article Open Access

Efficacy and safety of immune checkpoint inhibitors combined with anti‑angiogenic agents for advanced cervical cancer: A systematic review and meta‑analysis

Hengchang Chen, Xue Yang, Yulu Qin, Wentong Xu, Mingzhu Jiao, Xinyu Lu, Yaxu Su, Fengjuan Zhou, Yong Xin
Article Number: 387
Published online on: 02 July 2026

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Expression of Concern Open Access

[Expression of Concern] In vitro and in vivo targeting of bladder carcinoma with metformin in combination with cisplatin

Dong Wang, Xiaohou Wu
Article Number: 386
Published online on: 02 July 2026

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Article Open Access

Lymphocyte‑to‑C‑reactive protein ratio as a clinically feasible nutrition‑inflammation marker for predicting outcomes in patients with gastric cancer

Kai Liu, Lai Chang
Article Number: 385
Published online on: 02 July 2026

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Article Open Access

Identification and validation of aging‑related genes in patients with multiple myeloma

Huajing Liu, Senhua Song, Yingtao Wu, Yu Wang, Yueping Liu, Ying Liu
Article Number: 384
Published online on: 02 July 2026

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Retraction Open Access

[Retracted] miR‑331‑3p suppresses cell invasion and migration in colorectal carcinoma by directly targeting NRP2

Hongye Zhang, Ruiyu Wang, Mingxia Wang
Article Number: 383
Published online on: 01 July 2026

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Article Open Access

Air pollution and hepatocellular carcinoma: Integrated network toxicology, machine learning, molecular docking and multiomics analysis

Xiaorong Wang, Huihao Qin, Jing Jing, Yun Liu, Lei Guo, Hongquan Liu, Wei Zhang
Article Number: 382
Published online on: 30 June 2026

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Case Report Open Access

Cervical metastasis in breast cancer: A case report

Xinru Liu, Ke Sun, Hongming Zhu, Tonghua Du, Liyang Sheng, Bin Liu
Article Number: 381
Published online on: 30 June 2026

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Review Open Access

New and emerging strategies for targeting cancers: Challenges and opportunities (Review)

Sreenivasa R. Chinni, Arun K. Rishi, Kaladhar B. Reddy
Article Number: 380
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] MicroRNA‑663b enhances migration and invasion by targeting adenomatous polyposis coli 2 in colorectal carcinoma cells

Fenqiang Xiao, Wangbin Chen, Chao Yu, Gang Zhao
Article Number: 379
Published online on: 29 June 2026

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Journal Cover
October-2026 Volume 32 Issue 4

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Journal Metrics

Impact Factor: 2.1

CiteScore: 3.7

CiteScore Rank: Q3: #233/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

Evaluation of limb function after treatment with chemotherapy and carbon ion radiotherapy for Ewing sarcoma of the scapula: A report of three cases 

Noriko Kato, Takashi Yanagawa, Masahiko Okamoto, Tatsuya Ohno, Hirotaka Chikuda
Article Number: 424
Published online on: 23 July 2026

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Correction Open Access

[Corrigendum] Effect of antioxidants coenzyme Q10 and β‑carotene on the cytotoxicity of vemurafenib against human malignant melanoma

Changkun Hu, Yuan Huang, Peixiao Luo, Yixin Yang
Article Number: 423
Published online on: 23 July 2026

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