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Oncology Letters
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Print ISSN: 1792-1074 Online ISSN: 1792-1082
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December-2025 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

SBEM confers paclitaxel resistance in breast cancer via DUSP16‑mediated MAPK/AMPK pathway activation

Liang Liu, Ning Lu, Xiaomei Liu, Qingting Yi, Shengnan Li, Jie Wen, Huijuan Sun, Yuanming Du
Article Number: 607
Published online on: 21 October 2025

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Article Open Access

Role and molecular mechanisms of hypoxia‑derived exosomal miR‑301a on gemcitabine resistance in pancreatic cancer

Weiwei Qu, Wanyi Tan, Mengjie Ye, Weixiang Tang, Lijun Zhang, Guangtao Luo
Article Number: 606
Published online on: 21 October 2025

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Case Report

Multiple primary malignant neoplasms and long‑term survival: A case report

Biao Xie, Ke Huang, Shuibo Zhu
Article Number: 605
Published online on: 21 October 2025

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Article Open Access

m6A RNA methylation regulator‑associated genes drive metastasis and immune cell infiltration in skin cutaneous melanoma

Yi Geng, Sijia Zhao, Tianxiang Geng, Xiu-Lian Xu, Xiaodie Zhang
Article Number: 604
Published online on: 21 October 2025

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Article Open Access

Analysis of the efficacy and prognostic factors of gemcitabine combined with oxaliplatin in non‑Hodgkin lymphoma

Xiaobo Zhang, Guang Li, Feng Liu, Rui Shi, Jing Wen, Wen Wu, Jinqian Dai
Article Number: 603
Published online on: 21 October 2025

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Article Open Access

Stimulator of interferon genes signaling network‑driven prognostic signature for pancreatic cancer: Hub gene discovery with multimodal validation

Wenjing Yu, Junqun Liao, Jiayan Li, Yongquan Wu
Article Number: 602
Published online on: 21 October 2025

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Article Open Access

Gamma Knife consolidation therapy improves prognosis in patients with advanced epidermal growth factor receptor‑mutant lung adenocarcinoma treated with first‑generation epidermal growth factor receptor‑tyrosine kinase inhibitors

Bin Xu, Donghui Lu, Dongmei Wang, Huan Ma, Zhijie Li, Lijie Zhang, Meiqin Liu, Donglai Lv
Article Number: 601
Published online on: 17 October 2025

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Article Open Access

Identification of EFNA3 as candidate prognosis marker and potential therapeutic target for adrenocortical carcinoma

Yanghao Tai, Xinzhe Liu, Yifan Zhou, Jiwen Shang
Article Number: 600
Published online on: 17 October 2025

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Article Open Access

Inhibition of apoptosis in breast cancer cells by si‑FoxO3a through the protein digestion and absorption signaling pathway

Liying Sun, Zhongxu Wang, Yanxi Liu, Jiaxin Lv, Xiaotong Shao, Haoming Tang, Cheng Hu, Liang Cao, Yundong Zhao, Shuang Chen
Article Number: 599
Published online on: 17 October 2025

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Review Open Access

CCL2/CCR2 signaling pathway in tumorigenesis and metastasis (Review)

Ya Zhang, Bin Fan, Hang Yang, Gangxian Chen, Zhou Huang, Ying Li, Xiang Ma, Tiying Wang, Weiquan Wang, Linhao Cai, Lei Han, Yan Liu, Dongqi Li, Xianwei Chen, Yihao Yang, Zuozhang Yang
Article Number: 598
Published online on: 17 October 2025

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Article Open Access

Mechanistic role of the ILK‑S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma Corrigendum in /10.3892/ol.2026.15489

Yang Yang, Jia-Xin Luo, Yuan-Yang Li, Ke-Hong Guo, Lin Ye, Dan Zhao
Article Number: 597
Published online on: 16 October 2025

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Case Report Open Access

Submandibular adenoid cystic carcinoma presenting with liver metastasis as the initial symptom: A case report

Tianyi Li, Tingyao Ma, Yue Zhao, Shujing Zhang, Guoliang Yang, Xuelian Wang, Xudong Wang, Mingzhu Wang, Xi Zhao, Hongfei Liu, Jun Wu, Xiaoli Zhao, Xiaohong Chen
Article Number: 596
Published online on: 15 October 2025

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Case Report Open Access

Esophageal perforation in a patient with lung cancer after administration of bevacizumab combined with radiotherapy and chemotherapy: A case report

Qiang Jia, Yun-Long Zhou, Lan-Ying Duan, Hui-Chao Li, Gaowu Hu
Article Number: 595
Published online on: 15 October 2025

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Case Report

Gastrointestinal metastasis in prostate cancer and therapeutic implications: A case report

Marie-Anne Audisio, Anh-Tuan Nguyen, Evelyne Peroux, Jean-Laurent Lamboley, David Lussato, Marie Pautas, Hugo Picchi, Audrey Le Roy, Aline Barhli, Marie Dusaud, Hélène Vanquaethem, Antoine Schernberg, Carole Helissey
Article Number: 594
Published online on: 15 October 2025

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Review Open Access

Advancements in research on the role of the key glycolytic enzyme hexokinase 2 in the regulation of tumor immune evasion (Review)

Yiyang Qian, Xiaodan Zhu, Dong Niu, Quan Tang, Chunhui Jin
Article Number: 593
Published online on: 14 October 2025

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Review Open Access

Cellular senescence in cancer: Unveiling dual roles, tumor microenvironment dynamics and therapeutic innovations (Review)

Yatsu Lam, Jiaming Gu, Peihao Yin
Article Number: 592
Published online on: 14 October 2025

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Article Open Access

A novel defined cuproptosis‑related signature score to predict prognosis and immunotherapy efficacy in pancreatic cancer

Weiyu Ge, Yongchao Wang, Daiyuan Shentu, Ming Yue, Yanling Wang
Article Number: 591
Published online on: 14 October 2025

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Article Open Access

Multi‑omics and experimental validation unveil BDNF as a diagnostic biomarker and therapeutic target in endoplasmic reticulum stress‑driven lung adenocarcinoma: Therapeutic potential of Esketamine

Xiujuan Deng, Yujun Tan, Guangbo Tan, Heli Ning
Article Number: 590
Published online on: 14 October 2025

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Review Open Access

Role of signaling pathways in lung cancer development and advances in targeted therapies (Review)

Zhang Tao, Weiwei Shao, Haiyang Zhou, Shujing Xia, Jie Zeng, Jing Ren, Xueyang Wang, Hua Zhu
Article Number: 589
Published online on: 14 October 2025

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Article Open Access

Bortezomib overcomes TRAIL resistance in Burkitt's lymphoma by enhancing apoptosis via reactive oxygen species‑mediated DR5 upregulation and MAPK pathway activation

Jiajie Chen, Yujia You, Wei Zhao, Yichuan Zhou, Shiqi Pu, Xiaoyu Bai, Ping Yang, Minhui Li
Article Number: 588
Published online on: 14 October 2025

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Article Open Access

Prognostic role and mutational characteristics of N6‑methyladenosine‑related genes in lung adenocarcinoma

Jiahao Yang, Xiangpeng Chu, Zihao Chen, Yi Long, Jinghua Chen
Article Number: 587
Published online on: 14 October 2025

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Retraction Open Access

[Retracted] Nerve growth factor and its receptors on onset and diagnosis of ovarian cancer

Xiaolin Yu, Zhaoxia Liu, Rui Hou, Yijun Nie, Rensheng Chen
Article Number: 586
Published online on: 13 October 2025

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Case Report

Severe fluoropyrimidine toxicity in a patient with rectal adenocarcinoma with DPYD c.2846A>T heterozygous mutation: A case report

Sezai Tunc, Ogur Karhan
Article Number: 585
Published online on: 13 October 2025

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Article

Prognostic value of the postoperative CALLY index in T1/T2 clear cell renal cell carcinoma

Hiroshi Hirata, Nakanori Fujii, Takanori Tokunaga, Kosuke Shimizu, Keita Kobayashi, Koji Shiraishi
Article Number: 584
Published online on: 10 October 2025

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Review

Role and mechanistic study of long non‑coding RNA maternally expressed gene 3 in gastric cancer (Review)

Buyun Jia, Hui Cheng, Peizheng Yang, Xiangyu Wang, Shanshan Li, Jinghui Wang
Article Number: 583
Published online on: 10 October 2025

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Article Open Access

Survival and recurrence characteristics of patients with esophageal cancer with a pathological complete response after neoadjuvant immunochemotherapy followed by surgery: A multicenter propensity score matching study

Feng Wang, Xiangyang Yu, Dongjie Yan, Lei Yang, Jianfei Zhu, Ran Yang, Yi Han
Article Number: 582
Published online on: 10 October 2025

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Article

Machine learning‑based programmed cell death‑related index to predict prognosis and immunotherapy response in skin cutaneous melanoma

Xinyi Wang, Yuzhi Zheng, Shan Yang, Hongli Si, Wenqiu Chen, Siyuan Shen
Article Number: 581
Published online on: 09 October 2025

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Correction Open Access

[Corrigendum] UBE2T silencing suppresses proliferation and induces cell cycle arrest and apoptosis in bladder cancer cells

Yan Qing Gong, Ding Peng, Xiang Hui Ning, Xin Yu Yang, Xue Song Li, Li Qun Zhou, Ying Lu Guo
Article Number: 580
Published online on: 09 October 2025

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Article Open Access

Dynamic changes in tumor blood flow during chemotherapy: Implications in customized treatment for pancreatic cancer

Hiromitsu Maehira, Takeru Maekawa, Yoshihisa Tsuji, Haruki Mori, Nobuhito Nitta, Takeshi Sonoda, Reiko Otake, Soichiro Tani, Katsushi Takebayashi, Masatsugu Kojima, Sachiko Kaida, Toru Miyake, Masaji Tani
Article Number: 579
Published online on: 08 October 2025

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Review Open Access

Abnormal metabolic networks participate in invasion and migration of tumors of the digestive system (Review)

Jianxin Li, Weidong Zhang
Article Number: 578
Published online on: 08 October 2025

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Article Open Access

A clinical feature‑based nomogram for the personalized prediction of radioactive iodine therapy outcomes in patients with papillary thyroid carcinoma

Jingjia Cao, Huazhen Liang, Xiang Li, Xin Guan, Hao Xu
Article Number: 577
Published online on: 07 October 2025

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Review Open Access

Immune checkpoint biology in hepatocellular carcinoma (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 576
Published online on: 07 October 2025

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Article Open Access

Preoperative PD‑1+CD4+ lymphocytes reflect immunological and physical frailty and are associated with postoperative infectious complications following gastrectomy for gastric cancer

Naoyuki Uehata, Hironori Tsujimoto, Nozomi Ito, Toru Kubo, Hiromi Miyazaki, Hiroyuki Horiguchi, Keita Kouzu, Seiichiro Fujishima, Takafumi Suzuki, Risa Kariya, Asuma Ide, Yoshihisa Yaguchi, Hideki Ueno
Article Number: 575
Published online on: 07 October 2025

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Case Report Open Access

Primary retroperitoneal squamous cell carcinoma: A case report

Fang Zhang, Yuan Gui, Jing Zhang
Article Number: 574
Published online on: 06 October 2025

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Case Report

Papillary thyroid carcinoma with metastasis to the femur as a rare cause of femoral fracture: A case report

Jiahua Chen, Mi Zhang
Article Number: 573
Published online on: 06 October 2025

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Retraction Open Access

[Retracted] Effect of interventional embolotherapy on FHIT and p16 expression in hepatocellular carcinoma patients

Wei Xu, Xiaogai Qi, Xia Wang, Jize Sun
Article Number: 572
Published online on: 06 October 2025

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Article Open Access

GBP5 as a prognostic biomarker associated with immune cell infiltration, migration and invasion in clear cell renal cell carcinoma

Xiaobao Cheng, Shujiang Ye, Xiang Xu, Shuo Yang, Wei Zhao, Zhenquan Lu, Caiyong Lai
Article Number: 571
Published online on: 03 October 2025

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Article Open Access

FBXL22, a circadian‑regulated immune biomarker with pan‑cancer prognostic value and therapeutic potential in prostate cancer

Jin Liu, Maoyuan Feng, Jian Zhou, Shijie Yang, Yue Shi, Wenping Li
Article Number: 570
Published online on: 03 October 2025

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Article Open Access

Deciphering site‑specific histopathological parameters with potential clinical value in head and neck squamous cell carcinomas

Sofia-Eleni Tzorakoleftheraki, Vassiliki Kotoula, Georgios Karakatsoulis, Konstantinos Markou, Stavroula Pervana, Konstantinos Vlachtsis, Sofia Chrisafi, Amanda Psyrri, George Fountzilas, Prodromos Hytiroglou, Triantafyllia Koletsa
Article Number: 569
Published online on: 03 October 2025

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Article Open Access

Non‑surgical breast‑conserving treatment using Kochi oxydol‑radiation therapy for unresectable carcinomas II for patients with stage 0 to IIIC breast cancer

Akihiro Hori, Taiju Shimbo, Jun Ikenaga, Takaaki Itami, Mari Mukai, Kazuma Kobata, Takashi Ogawa, Ayaka Kihara, Mio Nakata, Yuuki Yoshino, Satoshi Takeno, Kanabu Nawa, Hiroto Yoshioka, Keiji Nihei, Hironori Akiyama, Ken Yoshida, Kosei Kimura, Mitsuhiko Iwamoto
Article Number: 568
Published online on: 02 October 2025

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Review Open Access

Pathogenic role and therapeutic targets of nuclear factor‑κB signaling pathway in cancer (Review)

Xing Li, Lu Chen, Ming Zeng, Jialun Deng, Fan Chen, Lingying Yu, Mingyue Ao
Article Number: 567
Published online on: 02 October 2025

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Case Report Open Access

Multimodal treatment for multifocal metastatic maxillary adenoid cystic carcinoma: A case report

Bin He, Jie Shi, Qing-Yan Yan, Ling Zhang
Article Number: 566
Published online on: 01 October 2025

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Review Open Access

Roles of β‑catenin protein in non‑small cell lung cancer (Review)

Lina Peng, Ran Gao, Liping Han, Tian Fu, Cuixia Bian
Article Number: 565
Published online on: 01 October 2025

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Article Open Access

Application value and safety of trilaciclib in first‑line chemotherapy combined with immunotherapy for extensive‑stage small cell lung cancer: A real‑world study

Yanping Cui, Hongjuan Zhang, Lizhi Wang, Xingyi Lou
Article Number: 564
Published online on: 01 October 2025

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Case Report Open Access

Multicentric Castleman disease detected during the evaluation of tongue cancer: A case report

Yuta Yasui, Satoshi Shimohama, Manabu Yamada, Kenichiro Suga, Masafumi Nishikawa, Seiji Asoda
Article Number: 563
Published online on: 01 October 2025

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Case Report Open Access

Sequential microwave ablation combined with radioactive iodine‑125 seed implantation successfully cured multiple metastases of gallbladder cancer: A case report

Wenjun Li, Yanwei Chen, Shuangshuang Zhao, Maohui An, Huajiao Zhao, Yun Cai, Jiayan Bao, Jiwen Qian, Baoding Chen
Article Number: 562
Published online on: 01 October 2025

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Article Open Access

Signature of immune infiltration‑related ferroptosis genes to predict the prognosis of patients with osteosarcoma

Ling-Rong Zeng, Guang-Hui Zhu, Hai-Bo Mei, Ge Yang
Article Number: 561
Published online on: 01 October 2025

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Article Open Access

Anticancer effects of the Kiperin Purple Collagen complex: Evidence from HCT116 and MIA PaCa‑2 cell models

Lutfiye Karcioglu Batur, Cuneyd Yavas, Nezih Hekim
Article Number: 560
Published online on: 01 October 2025

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Expression of Concern Open Access

[Expression of Concern] microRNA‑99a is downregulated and promotes proliferation, migration and invasion in non‑small cell lung cancer A549 and H1299 cells

Changjin Chen, Ziyi Zhao, Yu Liu, Dezhi Mu
Article Number: 559
Published online on: 01 October 2025

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Article Open Access

Leucine‑rich repeat‑containing G protein‑coupled receptor 4 promotes proliferation, invasion and migration, and inhibits apoptosis in non‑small cell lung cancer cells

Xiaoyu Duan, Xiangsen Liu, Yuchen Shan, Songfu Zhou, Ming Lou, Zhaojia Gao, Kai Yuan
Article Number: 558
Published online on: 30 September 2025

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Retraction Open Access

[Retracted] Treatment with a selenium‑platinum compound induced T‑cell acute lymphoblastic leukemia/lymphoma cells apoptosis through the mitochondrial signaling pathway

Feifei Wu, Wei Cao, Huaping Xu, Mingxia Zhu, Jing Wang, Xiaoyan Ke
Article Number: 557
Published online on: 29 September 2025

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Article Open Access

Serum fucosylated receptor expression‑enhancing protein 5 as a biomarker for early stage pancreatic cancer

Kazuyuki Sogawa, Riko Yonekubo, Momori Shimizu, Satoshi Muraoka, Jun Adachi, Shigetsugu Takano, Hirotaka Takizawa, Masayuki Ohtsuka, Takeshi Tomonaga
Article Number: 556
Published online on: 26 September 2025

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Case Report Open Access

Primary squamous thyroid cancer: A case report

Shuchang Dong, Xuewen Wang, Ziwen Zhou, Lingjun Feng, Qingliang Xu
Article Number: 555
Published online on: 26 September 2025

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Article Open Access

Transarterial infusion chemotherapy for severe hepatic dysfunction and poor performance status in diffuse hepatic metastasis: A case report

Xiao-Chun Chen, Xian-Qin Li, Yi Liu, Xu Zhang, Chuan Lin, Zhi-Ping Yuan
Article Number: 554
Published online on: 25 September 2025

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Article Open Access

Real‑world investigation for camrelizumab combined with apatinib in patients with advanced hepatocellular carcinoma

Liyang Yin, Yuanyuan Shi, Ruijia An, Yajing Hao, Haoran Huo, Jiadong Xue, Ruifeng Qin, Zengjiang Yuan
Article Number: 553
Published online on: 25 September 2025

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Article Open Access

Impact of SAMHD1 and phosphorylated ATM levels on the progression and prognosis of patients with soft tissue sarcoma

Yun Jae Kim, Young Jae Moon, Ae Ri Ahn, Ho Sung Park, Myoung Ja Chung, Woo Sung Moon, Kyu Yun Jang, Kyoung Min Kim
Article Number: 552
Published online on: 24 September 2025

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Article Open Access

Methionine‑MAT2A‑SAM axis controls lipid levels by regulating ACSL4

Chaoyi Xia, Jingshu Min
Article Number: 551
Published online on: 24 September 2025

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Article Open Access

Favorable survival of patients with nasopharyngeal carcinoma associated with metachronous multiple primary cancers: A retrospective study

Xin Huang, Ying Kong, Tianyu Wu, Zhen Meng, Min Kang
Article Number: 550
Published online on: 23 September 2025

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Article Open Access

Protein arginine methyltransferase 7 regulates the cell cycle and promotes the progression of prostate cancer

Hongyuan Wan, Hangshen Zhou, Jiandong Gui, Dongjie Yang, Rong Wang, Jiang Ni, Sheng Wu, Yan Qin, Qiaowei Qi, Lijie Zhu, Ninghan Feng, Yuanyuan Mi
Article Number: 549
Published online on: 23 September 2025

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Case Report Open Access

Adrenal cyst misdiagnosed with cystic renal cell carcinoma: A case report

Xin Huang, Mengyu Zhang, Yijun Zhan, Ce Chen, Xinhua Zhang, Yaozhong Xu
Article Number: 548
Published online on: 23 September 2025

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Correction Open Access

[Corrigendum] Characteristics of primary side population cervical cancer cells

Zhen-Tong Wei, Xiao-Wei Yu, Jia-Xue He, Yan Liu, Song-Ling Zhang
Article Number: 547
Published online on: 23 September 2025

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Article Open Access

Clinicopathological characteristics and treatment of patients with colorectal neuroendocrine carcinoma: A retrospective study of 157 cases

Meng Dai, Shuang Sun, Xin Liu, Hulun Li
Article Number: 546
Published online on: 23 September 2025

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Article Open Access

Peripheral blood tumor marker levels can indicate the location of lung cancer metastasis

Jiahao Wang, Xiaobo Wang, Yingjia Mao, Hongmei Niu, Fuqian Zhao, Daofu Shen, Lei Wang
Article Number: 545
Published online on: 23 September 2025

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Retrospective comparisons of the dosimetric differences between coplanar and non‑coplanar volume‑modulated arc therapy in patients with pediatric brainstem glioma

Zhanquan Lei, Junjie Jing, Yuequan Shi, Bo Gao, Kongfeng Shao, Yiqun Liu, Junjin Yan
Article Number: 544
Published online on: 22 September 2025

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Preoperative peripheral blood routine indicators as predictors of prognosis and diagnosis in glioma under the 2021 World Health Organization classification

Qing Yang, Jiaying Ni, Jiandong Zhu, Xiao Fan, Xing Cheng, Yun Yu, Zhumei Shi, Yingyi Wang, Yongping You
Article Number: 543
Published online on: 22 September 2025

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Case Report Open Access

Efficacy of combined immunotherapy and chemotherapy in recurrent non‑small cell lung cancer during durvalumab maintenance therapy: A case report

Yuki Maze, Takahiro Mitsumura, Hiroshi Nakahama, Tatsuya Kato, Yui Takahashi, Yuichiro Nei, Shigeo Hanada, Atsushi Miyamoto, Hironori Uruga, Takeshi Fujii, Meiyo Tamaoka
Article Number: 542
Published online on: 22 September 2025

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Efficacy and safety of fruquintinib combined with immunotherapy in later‑line treatment of metastatic colorectal cancer

Ying Peng, Sheng Li, Liangjun Zhu
Article Number: 541
Published online on: 22 September 2025

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Prognostic value of M2 macrophage‑related genes and their importance in the immunotherapy response in hepatocellular carcinoma

Aiping Wang, Xiaojing Li, Zi Wang, Lan Chen
Article Number: 540
Published online on: 22 September 2025

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Histone acetyltransferase 1 promotes ovarian cancer progression by regulating cell proliferation and the cell cycle

Xiao Han, Ling Liu, Jing Li, Yunxiao Zhi, Lanlan Zhao, Limin Yuan, Xuezhe Ouyang, Jie Liu
Article Number: 539
Published online on: 22 September 2025

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Retraction Open Access

[Retracted] MicroRNA‑320a downregulation mediates human liver cancer cell proliferation through the Wnt/β‑catenin signaling pathway

Caicheng Lu, Zengwei Liao, Minxian Cai, Guirong Zhang
Article Number: 538
Published online on: 22 September 2025

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Journal Cover
May-2026 Volume 31 Issue 5

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Article Open Access

TBX20 regulates epithelial‑mesenchymal transition, maintains tumor stemness and immune factor expression, and promotes immune escape in lung cancer

Chuncai Xu, Peng Zhou, Yanting Zhang, Lili Li, Guowen Wang
Article Number: 207
Published online on: 30 March 2026

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Silencing of small nuclear ribonucleoprotein polypeptide B inhibits the progression of esophageal squamous cell carcinoma

Haiyang Guo, Ji Zuo, Guangbing Hu, Yong Tang, Liuyi Lu, Zichen Luo, Xinrui Chen, Xiaobo Wang, Xianfei Wang
Article Number: 206
Published online on: 30 March 2026

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Article

Prognostic and diagnostic significance of serum p53 antibody levels in patients with surgically treated pancreatic cancer

Rei Okada, Yuichiro Otsuka, Yoji Kajiwara, Yu Matsumoto, Yuko Ito, Hideaki Shimada
Article Number: 205
Published online on: 30 March 2026

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Update on the clinical features, treatment and histogenesis of combined hepatocellular-cholangiocarcinoma

Junwen Hu, Jiahao Chen, Chenglei Yang, Yapeng Qi, Jie Zhang, Rui Song, Jianhong Zhong, Bangde Xiang
Article Number: 204
Published online on: 30 March 2026

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Lung squamous cell carcinoma downregulates haptoglobin expression to inhibit M2 macrophage ferroptosis via the hemoglobin‑dependent CD163/HO‑1 pathway

Weijing Xie, Ying-Ying Lin, Guang-Hong Tan, Feng-Ying Huang
Article Number: 203
Published online on: 30 March 2026

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Immune‑imaging biomarkers: Prognostic value of splenic volume and circulating lymphocytes in upper tract urothelial carcinoma

Chien-Hsiung Lo, Kun-Che Lin, Chu-An Wang, Che-Yuan Hu, Chien-Hui Ou, Hau-Chern Jan
Article Number: 202
Published online on: 30 March 2026

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Whole‑exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma

Yang Wang, Lizhi Zhang, Xueyan Xia, Xiancheng Li
Article Number: 201
Published online on: 30 March 2026

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Efficacy and safety of concurrent chemoradiotherapy following neoadjuvant chemoimmunotherapy in patients with stage III NSCLC who experienced neoadjuvant failure: A real-world study

Ruoxuan Li, Luping Pan, Fujuan Zeng, Jingyu Huang, Ziye Chen, Chengyi Liu, Zhimin Zeng
Article Number: 200
Published online on: 30 March 2026

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Curcumin induces and enhances the PARP1‑mediated parthanatos in diffuse large B cell lymphoma

Yayun Wang, Ruili Qi, Xuanzhu Zhao, Hanwei Mei, Minghan Qiu, Fengting Liu, Huaqing Wang
Article Number: 199
Published online on: 30 March 2026

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Immunotherapy‑based treatment patterns and clinical outcomes across lines of therapy in microsatellite stable metastatic colorectal cancer: A real‑world study

Wen-Si Zhao, Shi-Jing Ma, Tao Zhang, De-Dong Cao
Article Number: 198
Published online on: 27 March 2026

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Efficacy and safety of blinatumomab combination therapy in high‑risk B‑cell acute lymphoblastic leukemia: A systematic review and meta‑analysis

Mei Wang, Xinlin Yu, Zhongqing Zou, Yan He, Lvlin Chen, Ying Lan
Article Number: 197
Published online on: 26 March 2026

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Article Open Access

Schisandrin B suppresses cholangiocarcinoma by targeting the ROS/p38 MAPK/NF‑κB axis

Junhao Yang, Wenying Long, Xiaoxiao Wu, Xiaohui Yang, Qiang Hong, Shuai Wang
Article Number: 196
Published online on: 26 March 2026

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Review Open Access

Role of non‑coding RNAs in O6‑methylguanine‑DNA methyltransferase‑positive glioblastoma (Review)

Yunyan Guo, Jun Guo, Wenyan Xiao, Yanxin Lu
Article Number: 195
Published online on: 26 March 2026

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Case Report Open Access

A rare case of uterine carcinosarcoma in a 21‑year‑old woman with hereditary breast and ovarian cancer syndrome: A case report

Yasushi Iida, Ayane Kosuge, Yoko Saito, Taichi Irie, Jun Matsushima, Makoto Iizuka, Satoshi Takakura
Article Number: 194
Published online on: 26 March 2026

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Article Open Access

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta‑analysis

Yu Qiao, Huiyao Li, Yanping Feng, Shuai Liang, Dong Hua
Article Number: 193
Published online on: 26 March 2026

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Review Open Access

Dual role of exosomes in pancreatic cancer: Underlying mechanisms and research advances (Review)

Zhao Guo, Qingfeng Liu
Article Number: 192
Published online on: 26 March 2026

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Article Open Access

Pomegranate peel‑derived exosome‑like nanoparticles: A discarded treasure trove for colorectal cancer treatment

Yifei Dong, Qin Yuan, Chao Chen, Zheng Zhang
Article Number: 191
Published online on: 26 March 2026

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SETD4 as a marker of disease burden and treatment response in childhood acute lymphoblastic leukemia

Luis Augusto Muniz Telles, Mariana Braccialli De Loyola, Luis Henrique Toshihiro Sakamoto, Doralina Do Amaral Ramos Rabello, Andrea Barretto Motoyama, Fabio Pittella‑Silva
Article Number: 190
Published online on: 24 March 2026

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Case Report Open Access

Comprehensive treatment for two patients with small cell neuroendocrine carcinoma of the liver: A case report and literature review

Ruizeng Feng, Hao Wang, Yang Zhao, Xue Zhang, Hongfang Tuo, Xing Xu
Article Number: 189
Published online on: 24 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑like growth factor‑1 receptor knockdown enhances radiosensitivity via the HIF‑1α pathway and attenuates ATM/H2AX/53BP1 DNA repair activation in human lung squamous carcinoma cells

Xiaoxing Liu, Haiyan Chen, Xin Xu, Ming Ye, Hongbin Cao, Lei Xu, Yanli Hou, Jianmin Tang, Di Zhou, Yongrui Bai, Xiumei Ma
Article Number: 188
Published online on: 23 March 2026

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Case Report Open Access

Painless perianal mucinous adenocarcinoma: A case report and literature review

Jianping Shi, Xiaoying Wang, Junjie Yang, Guofeng Li, Yanjie Zhang
Article Number: 187
Published online on: 20 March 2026

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Methylglyoxal‑derived glycated albumin enhances the stemness potential of invasive ductal carcinoma‑derived breast cancer stem‑like cell line KAIMRC1

Maram Aldawood, Mariam K. Alamoudi, Abdulmonem A. Alsaleh, Nouf Alharbi, Sarah Huwaizi, Rehab Alroshody, Rizwan Ali, Rafa Almeer, Sabine Matou-Nasri
Article Number: 186
Published online on: 19 March 2026

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Article Open Access

Proteomic and immunocytochemical analyses of squamous components in two‑ and three‑dimensional‑cultured pancreatic ductal adenocarcinoma cell lines

Yuuki Shichi, Hiroki Tsumoto, Masakazu Fujiwara, Keisuke Nonaka, Yasuko Hasegawa, Seiichi Shinji, Hirofumi Rokutan, Kimimasa Takahashi, Tomio Arai, Yuri Miura, Toshiyuki Ishiwata
Article Number: 185
Published online on: 19 March 2026

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Review Open Access

Metabolic reprogramming‑a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review)

Xueting Zhao, Fang Chen, Huibin Li
Article Number: 184
Published online on: 18 March 2026

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Article Open Access

Efficacy of induction chemotherapy combined with standard chemoradiotherapy vs. standard chemoradiotherapy monotherapy in locally advanced cervical cancer:  A systematic review and meta‑analysis

Xinyu Lu, Yaxu Su, Wentong Xu, Tianyou Tang, Fengjuan Zhou, Dehong Yu, Yilong Guo, Yong Xin
Article Number: 183
Published online on: 18 March 2026

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Article Open Access

Predictive performance of image processing techniques in the diagnosis of bone metastasis: A meta‑analysis of a confusion matrix

Yupeng Hu, Wen Liao, Ying Er, Qifeng Tao
Article Number: 182
Published online on: 18 March 2026

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Expression of Concern Open Access

[Expression of Concern] Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma 

Yun-Bao Guo, Yi-Meng Shao, Jing Chen, Song-Bai Xu, Xing-Dong Zhang, Mao-Ren Wang, Hai-Yan Liu
Article Number: 181
Published online on: 18 March 2026

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Article Open Access

Optimizing safety and efficacy in radiotherapy for external auditory canal cancer

Yuto Imai, Taiki Takaoka, Natsuo Tomita, Mayu Kuno, Akifumi Miyakawa, Chikao Sugie, Shinya Otsuka, Kaoru Uchiyama, Dai Okazaki, Masanari Niwa, Akira Torii, Nozomi Kita, Masanosuke Oguri, Seiya Takano, Takuma Matoba, Daisuke Kawakita, Shinichi Iwasaki, Akio Hiwatashi
Article Number: 180
Published online on: 17 March 2026

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Correction Open Access

[Corrigendum] Inhibition of microRNA‑221‑5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells   

Fang-Yi Fan, Rui Deng, Si-Han Lai, Qin Wen, Yunjing Zeng, Lei Gao, Yao Liu, Peiyan Kong, Jiangfan Zhong, Yi Su, Xi Zhang
Article Number: 179
Published online on: 17 March 2026

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Article

DNA hypermethylation of nonspecific cytotoxic cell receptor protein 1 and poor prognosis of pancreatic cancer

Mai Nakamura, Teruki Hagiwara, Kazuhiko Yamada, Toru Igari, Yuki Fukumura, Akio Saiura, Nobuyuki Takemura, Norihiro Kokudo, Yuki I. Kawamura
Article Number: 178
Published online on: 17 March 2026

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Case Report

Limbic encephalitis associated with anti‑Hu antibody induced by atezolizumab treatment for small cell lung cancer: A case report

Zhaohui Li, Hanping Wang
Article Number: 177
Published online on: 17 March 2026

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Case Report

Administration of tirabrutinib suspension in a patient with primary central nervous system lymphoma: A case report

Takeo Yasu, Hiroaki Ohta, Yoshito Gando, Masayuki Kobayashi
Article Number: 176
Published online on: 17 March 2026

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Review

Postoperative complications in patients with chemotherapy‑induced acute myeloid leukemia (Review)

Cen-Hung Lin, Hang-Tsung Liu, Ching-Hua Hsieh
Article Number: 175
Published online on: 17 March 2026

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Retraction Open Access

[Retracted] MicroRNA-27a functions as an oncogene in human osteosarcoma by targeting CCNG1  

Tao Lin, Quanping Ma, Yuefeng Zhang, Hongfei Zhang, Jiapeng Yan, Changhong Gao
Article Number: 174
Published online on: 16 March 2026

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Case Report Open Access

Bone marrow metastasis from gastric cancer: A case report

Xinyi Wei, Wenli Dai, Pengyi Deng
Article Number: 173
Published online on: 12 March 2026

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Article

Effect of apalutamide dosage on the incidence of cutaneous adverse events and prostate‑specific antigen reduction in patients with prostate cancer

Takuya Matsuyama, Michio Kimura, Makiko Go, Shiori Yamada, Mitsuhiro Nishimura, Hiromi Murase, Rina Matsuyama, Eiseki Usami
Article Number: 172
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first  

Ning Liu, Rui Zhang, Xiaoming Zhao, Jiaming Su, Xiaolei Bian, Jinsong Ni, Ying Yue, Yong Cai, Jingji Jin
Article Number: 171
Published online on: 12 March 2026

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Article Open Access

Skeletal muscle index at the third lumbar vertebra/BMI are positively associated with 1‑year overall survival in male patients with hepatocellular carcinoma treated with immune checkpoint inhibitors

Juan Li, Yang Wang, Songtao Liu, Huili Wu, Xin Hua, Qinghua Meng
Article Number: 170
Published online on: 11 March 2026

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Correction Open Access

[Corrigendum] Inhibition of Rac1 reverses enzalutamide resistance in castration‑resistant prostate cancer

Xiaoliang Chen, Lili Yin, Gan Qiao, Yanhua Li, Baoyuan Li, Yunfeng Bai, Feng Feng
Article Number: 169
Published online on: 11 March 2026

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Article Open Access

Integrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non‑functioning pituitary adenomas

Jianyao Mao, Xi Chen, Wentao Zheng, Bosen Liu, Zhangyu Li, Yukui Li, Ping Zhong, Sifang Chen, Guowei Tan, Chen Wang, Jinli Sun
Article Number: 168
Published online on: 10 March 2026

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Retraction Open Access

[Retracted] MSK1 downregulation is associated with neuronal and astrocytic apoptosis following subarachnoid hemorrhage in rats

Bo Ning, Geng Guo, Hong Liu, Lei Ning, Bao-Liang Sun, Zhen Li, Shuo Wang, Zheng-Wen Lv, Cun-Dong Fan
Article Number: 167
Published online on: 09 March 2026

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Article Open Access

CANT1 as a novel prognostic biomarker in triple‑negative breast cancer

Doğan Bayram, Aysel Çolak, Şefi̇ka Karabulut, Sema Nur Özsan Çelebi̇, Emre Hafizoğlu, Duri̇ye Özer Türkay, Öznur Bal, Efnan Algin, Şebnem Yücel, Mehmet Ali̇ Nahi̇t Şendur, Burak Ci̇velek, Gökhan Uçar
Article Number: 166
Published online on: 09 March 2026

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Article Open Access

RNA methyltransferase NSUN2 enhances vasculogenic mimicry and malignant progression of cervical cancer through upregulation of MMP‑9

Jun Luo, Guang Li, Mei Ye, Xiaoqing Xu, Mengwen Qi, Jian Huang, Kong Shan, Lili Qu, Hengchuan Shi
Article Number: 165
Published online on: 06 March 2026

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Article Open Access

Long-term effects of using pegylated recombinant human granulocyte colony-stimulating factor following chemotherapy: A real-world study on patients with ovarian cancer

Weimin Zhang, Nenghuan Tang, Yiyue Wang, Tiantian Feng, Min Yong, Yuhua Zeng
Article Number: 164
Published online on: 06 March 2026

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Case Report Open Access

Primary clear‑cell carcinoma of the liver with gastric antrum metastasis: Integrated management with targeted therapy, immunotherapy and salvage surgery: A case report

Lianshan Zhan, Qianwei Li, Tian Tian, Long Wang
Article Number: 163
Published online on: 06 March 2026

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Case Report

Diagnostic and surgical challenges of a lymph node metastasis from occult gastric cancer mimicking a pancreatic head tumor: A case report

Takuya Ando, Yuki Hirose, Kazuyasu Takizawa, Jun Sakata, Hirosuke Ishikawa, Shun Abe, Yusuke Kawachi, Mae Nakano, Hiroshi Ichikawa, Yoshifumi Shimada, Toshifumi Wakai
Article Number: 162
Published online on: 05 March 2026

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Article Open Access

Integrated analysis of therapeutic strategies and prognostic factors in advanced lung adenocarcinoma: Retrospective study with emphasis on gene assays, multimodality treatment approaches and predictive machine learning models

Shingchern You, Shiuan-Wen Chen, Irene Chen, Wei-Teing Chen
Article Number: 161
Published online on: 05 March 2026

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Review Open Access

Tumor‑muscle communication in cancer‑associated cachexia (Review)

Lily Berríos‑Contreras, Matías Meza‑Valenzuela, Nelson Brown, Claudio Valenzuela, Silvia Busquets, Francisco Javier López‑Soriano, Andrew Fg Quest, Rodrigo Moore‑Carrasco
Article Number: 160
Published online on: 05 March 2026

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Case Report Open Access

Pseudocirrhosis due to liver metastasis from lung squamous cell carcinoma: A case report

Qian Liu, Yufeng Lu, Dan Wang, Juan Yao, Ying Liu
Article Number: 159
Published online on: 04 March 2026

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Case Report

Malignant mesothelioma of the tunica vaginalis testis: A case report

Yuanchen Lu, Junjun Miu, Zhongru Fan, Zheng Zhi, Lei He, Junpeng Deng, Xianhua Shao, Jingqi Hua, Yichen Qian, Jianjun Xie
Article Number: 158
Published online on: 04 March 2026

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Case Report Open Access

Metachronous primary non‑small cell lung cancer and mucinous tubular and spindle cell carcinoma of the left kidney: A case report

Jin-Xia Zhao, Wei Zhu, Jie-Bin Pan, Peng-Fei Sun
Article Number: 157
Published online on: 04 March 2026

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Article Open Access

Telomere maintenance mechanisms are activated in ganglioneuroblastoma and ganglioneuroma

Motoki Sugawara, Masayuki Haruta, Miki Ohira, Jesmin Akter, Ritsuko Onuki, Ryuichi P. Sugino, Kiyohiro Ando, Atsuko Nakazawa, Hajime Okita, Tetsuya Takimoto, Tomoko Iehara, Tsugumichi Koshinaga, Shuichiro Uehara, Takehiko Kamijo
Article Number: 156
Published online on: 04 March 2026

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Article Open Access

Leucovorin enhances curcumin‑induced inhibition of cell viability and ferroptosis in colorectal cancer cells

Rui Meng, Qianqian Xu, Xue Wang, Hongwei Xu
Article Number: 155
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Effects of 17‑allylamino‑17‑demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT‑116  cells

Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Ding
Article Number: 154
Published online on: 03 March 2026

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Review

Application of carbonic anhydrase IX‑targeted radiopharmaceuticals in the diagnosis and treatment of clear cell renal cell carcinoma (Review)

Min Wang, Yuqin Li, Wenbo Yang, Bin Liu
Article Number: 153
Published online on: 02 March 2026

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Review Open Access

Targeting ICMT: A promising strategy in cancer treatment (Review)

Jinghong Hu, Ying Xiao, Jingyi Tang
Article Number: 152
Published online on: 02 March 2026

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Review Open Access

Orchestrating organotropism: miRNA‑driven mechanisms of site‑specific metastasis in triple‑negative breast cancer (Review)

Rigude Bu, Liu Bo
Article Number: 151
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple‑negative breast carcinomas

Rong-Hui Li, Wen-He Huang, Jun-Dong Wu, Cai-Wen Du, Guo-Jun Zhang
Article Number: 150
Published online on: 02 March 2026

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Case Report Open Access

Adenoid cystic carcinoma of the vulva: A case report and literature review

Zhiying Ding, Guiqiu Liu, Chuanshan Zhang
Article Number: 149
Published online on: 26 February 2026

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Journal Cover
June-2026 Volume 31 Issue 6

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Journal Metrics

Impact Factor: 2.2

CiteScore: 4.6

CiteScore Rank: Q2: #178/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.568

SCImago Journal Rank (SJR): 0.663

Case Report Open Access

Primary thoracic synovial sarcoma in a 45‑year‑old male: A case report and literature review

Baolei Liang, Jichun Zhang, Mingqiang Shen, Cuilian Li, Mingxiao Hou, Yunen Liu, Qingyong Cai
Article Number: 209
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] Pseudomonas aeruginosa‑mannose‑sensitive hema-gglutinin inhibits proliferation and induces apoptosis in a caspase‑dependent manner in human bladder cancer cell lines

Yi-Ping Zhu, Xiao-Jie Bian, Ding-Wei Ye, Xu-Dong Yao, Shi-Lin Zhang, Bo Dai, Yi-Jun Shen
Article Number: 208
Published online on: 31 March 2026

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