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Review Open Access

Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)

  • Authors:
    • Ruibing Yang
    • Jiali Gao
    • Yunyun Cheng
    • Caihong Lu
    • Juan Li
  • View Affiliations / Copyright

    Affiliations: Department of Labor, Xingtai City Central Hospital, Xingtai, Hebei 054000, P.R. China, The Second Department of Labor, Xingtai City Central Hospital, Xingtai, Hebei 054000, P.R. China, Department of Obstetrics and Gynecology, Affiliated Hospital of The Noncommissioned Officer School, The Army Medical University, Shijiazhuang, Hebei 050047, P.R. China, The First Department of Labor, Xingtai City Central Hospital, Xingtai, Hebei 054000, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 65
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    Published online on: December 3, 2025
       https://doi.org/10.3892/ol.2025.15418
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Abstract

Epithelial ovarian cancer (EOC) is a leading cause of mortality among gynecological malignancies, predominantly due to late‑stage diagnoses and complex management challenges. Traditional treatment strategies, primarily centered on extensive cytoreductive surgery and platinum‑based chemotherapy, have seen notable improvements through the integration of laparoscopy and robotic‑assisted procedures. The safety and efficacy of minimally invasive techniques (MITs) have been demonstrated in early‑stage EOC, although their applicability in advanced stages requires further investigation. Additionally, molecular‑based and immunotherapies, including poly(ADP‑ribose) polymerase inhibitors, angiogenesis inhibitors and RNA‑based treatments, offer promising adjuncts to MITs by targeting cancer‑specific pathways with precision. Despite these innovations, patient selection, surgical expertise and adherence to oncological safety standards remain key factors in determining the efficacy and safety of MITs in EOC management. Future directions emphasize the need for standardized protocols, enhanced imaging techniques and real‑time molecular monitoring, which aim to transition EOC management toward a minimally invasive, patient‑centered approach. The present review discussed the advancements in MITs and their role in the management of EOC, with a focus on their impact on surgical outcomes, survival rates and patient quality of life.
View Figures

Figure 1

Risk factors associated with the
development of epithelial ovarian cancer.

Figure 2

Schematic illustration of management
methods for epithelial ovarian cancer. CAR, chimeric antigen
receptor.
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Copy and paste a formatted citation
Spandidos Publications style
Yang R, Gao J, Cheng Y, Lu C and Li J: Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review). Oncol Lett 31: 65, 2026.
APA
Yang, R., Gao, J., Cheng, Y., Lu, C., & Li, J. (2026). Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review). Oncology Letters, 31, 65. https://doi.org/10.3892/ol.2025.15418
MLA
Yang, R., Gao, J., Cheng, Y., Lu, C., Li, J."Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)". Oncology Letters 31.2 (2026): 65.
Chicago
Yang, R., Gao, J., Cheng, Y., Lu, C., Li, J."Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)". Oncology Letters 31, no. 2 (2026): 65. https://doi.org/10.3892/ol.2025.15418
Copy and paste a formatted citation
x
Spandidos Publications style
Yang R, Gao J, Cheng Y, Lu C and Li J: Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review). Oncol Lett 31: 65, 2026.
APA
Yang, R., Gao, J., Cheng, Y., Lu, C., & Li, J. (2026). Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review). Oncology Letters, 31, 65. https://doi.org/10.3892/ol.2025.15418
MLA
Yang, R., Gao, J., Cheng, Y., Lu, C., Li, J."Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)". Oncology Letters 31.2 (2026): 65.
Chicago
Yang, R., Gao, J., Cheng, Y., Lu, C., Li, J."Roles of minimally invasive techniques in the management of epithelial ovarian cancer (Review)". Oncology Letters 31, no. 2 (2026): 65. https://doi.org/10.3892/ol.2025.15418
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